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CCEENNLLEEEnd-of-Life Nursing Education Consortium
International CurriculumInternational Curriculum
Symptom Management
Symptom Management
EE NN EE CCLL International CurriculumInternational Curriculum
Essential Elements of Symptom Management Essential Elements of
Symptom Management
• Ongoing assessment and evaluation
• Requires interdisciplinary teamwork
• Financial concerns (affordable options)
• Research is needed
Coyne et al., 2010
• Ongoing assessment and evaluation
• Requires interdisciplinary teamwork
• Financial concerns (affordable options)
• Research is needed
Coyne et al., 201022
EE NN EE CCLL International CurriculumInternational Curriculum
Symptoms and SufferingSymptoms and Suffering
• Symptoms create suffering and distress
• Need for interdisciplinary care• Determine clinical intervention– Benefit (s)– Burden (s)– Risk (s)
• Symptoms create suffering and distress
• Need for interdisciplinary care• Determine clinical intervention– Benefit (s)– Burden (s)– Risk (s)
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Common SymptomsCommon Symptoms• Respiratory– Dyspnea, cough
• GI– Anorexia/cachexia, constipation, diarrhea,
nausea/vomiting• Psychological– Depression, anxiety,
delirium/agitation/confusion• General/Systemic– Fatigue/weakness– Seizures– Fevers– Malaria
• Respiratory– Dyspnea, cough
• GI– Anorexia/cachexia, constipation, diarrhea,
nausea/vomiting• Psychological– Depression, anxiety,
delirium/agitation/confusion• General/Systemic– Fatigue/weakness– Seizures– Fevers– Malaria
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DyspneaDyspnea
• Distressing shortness of breath• Associated diseases
Dudgeon, 2010
• Distressing shortness of breath• Associated diseases
Dudgeon, 2010
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Causes of DyspneaCauses of Dyspnea
• Major pulmonary causes• Major cardiac causes• Major neuromuscular causes• Other causes
• Major pulmonary causes• Major cardiac causes• Major neuromuscular causes• Other causes
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Assessment of DyspneaAssessment of Dyspnea
• Use subjective report• Clinical assessment– Physical exam– Diagnostic tests
Dudgeon, 2010
• Use subjective report• Clinical assessment– Physical exam– Diagnostic tests
Dudgeon, 2010
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Treatment of DyspneaTreatment of Dyspnea
• Treating symptoms or underlying cause
• Pharmacologic treatments– Opioids– Bronchodilators– Diuretics– Other
Dudgeon, 2010; Jacobs, 2003
• Treating symptoms or underlying cause
• Pharmacologic treatments– Opioids– Bronchodilators– Diuretics– Other
Dudgeon, 2010; Jacobs, 2003
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Treatment of DyspneaTreatment of Dyspnea
• Nonpharmacologic– Oxygen– Counseling– Pursed lip breathing– Energy conservation– Fans, elevation– Other
Dudgeon, 2010; Kravits & Berenson, 2010
• Nonpharmacologic– Oxygen– Counseling– Pursed lip breathing– Energy conservation– Fans, elevation– Other
Dudgeon, 2010; Kravits & Berenson, 2010
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CoughCough
• Common symptom in advanced disease
• Causes pain, fatigue, insomnia
Dudgeon, 2010
• Common symptom in advanced disease
• Causes pain, fatigue, insomnia
Dudgeon, 2010
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Causes of CoughCauses of Cough
• Assess underlying cause (e.g. infection, sinusitis, reflux)
• Assess type of cough• Assess associated symptoms• Diagnostic tests may be needed
Dudgeon, 2010
• Assess underlying cause (e.g. infection, sinusitis, reflux)
• Assess type of cough• Assess associated symptoms• Diagnostic tests may be needed
Dudgeon, 2010
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Pharmacologic Interventions for Cough
Pharmacologic Interventions for Cough
• Suppressants/expectorants• Antibiotics• Steroids• Anticholinergics
• Suppressants/expectorants• Antibiotics• Steroids• Anticholinergics
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Non-Pharmacologic Interventions for Cough
Non-Pharmacologic Interventions for Cough
• Chest PT• Humidifier• Positioning
• Chest PT• Humidifier• Positioning
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Anorexia and CachexiaAnorexia and Cachexia
• Anorexia - loss of appetite, usually with decreased intake
• Cachexia - lack of nutrition and wasting
Wholihan & Kemp, 2010
• Anorexia - loss of appetite, usually with decreased intake
• Cachexia - lack of nutrition and wasting
Wholihan & Kemp, 2010
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Causes of Anorexia and Cachexia
Causes of Anorexia and Cachexia
• Disease related• Psychological• Treatment related
Fearon et al., 2010; Wholihan & Kemp, 2010
• Disease related• Psychological• Treatment related
Fearon et al., 2010; Wholihan & Kemp, 2010
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Assessment of Anorexia and Cachexia
Assessment of Anorexia and Cachexia
• Physical findings• Impact on function and quality of life• Calorie counts/daily weights• Lab tests• Skin breakdown
Wholihan & Kemp, 2010
• Physical findings• Impact on function and quality of life• Calorie counts/daily weights• Lab tests• Skin breakdown
Wholihan & Kemp, 2010
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Treatment of Anorexia and Cachexia
Treatment of Anorexia and Cachexia
• Dietary consultation• Medications• Parenteral/enteral nutrition• Odor control• Counseling
Earthman, 2002; MacDonald, 2003; Wholihan & Kemp, 2010
• Dietary consultation• Medications• Parenteral/enteral nutrition• Odor control• Counseling
Earthman, 2002; MacDonald, 2003; Wholihan & Kemp, 2010
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ConstipationConstipation
• Infrequent passage of stool• Frequent symptom in palliative
care• Prevention is key
• Infrequent passage of stool• Frequent symptom in palliative
care• Prevention is key
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Causes of ConstipationCauses of Constipation
• Disease related (e.g. obstruction, hypercalcemia, neurologic, inactivity)
• Treatment related (e.g. opioids, other meds)
• Disease related (e.g. obstruction, hypercalcemia, neurologic, inactivity)
• Treatment related (e.g. opioids, other meds)
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Assessment of ConstipationAssessment of Constipation
• Bowel history• Abdominal assessment• Rectal assessment• Medication review
Economou, 2010
• Bowel history• Abdominal assessment• Rectal assessment• Medication review
Economou, 2010
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Treatment of ConstipationTreatment of Constipation
• Medications• Dietary/fluids• Other approaches
Economou, 2010
• Medications• Dietary/fluids• Other approaches
Economou, 2010
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DiarrheaDiarrhea
• Frequent passage of loose, nonformed stool
• Effects (e.g. fatigue, caregiver burden, skin breakdown)
• Frequent passage of loose, nonformed stool
• Effects (e.g. fatigue, caregiver burden, skin breakdown)
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Causes of DiarrheaCauses of Diarrhea
• Disease related• Malabsorption• Concurrent diseases• Psychological• Treatment related
• Disease related• Malabsorption• Concurrent diseases• Psychological• Treatment related
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Assessment of DiarrheaAssessment of Diarrhea
• Bowel history• Medication review• Infectious processes
• Bowel history• Medication review• Infectious processes
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Treatment of DiarrheaTreatment of Diarrhea
• Treat underlying cause• Dietary modifications• Hydration• Pharmacologic agents
• Treat underlying cause• Dietary modifications• Hydration• Pharmacologic agents
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Nausea and VomitingNausea and Vomiting
• Common in advanced disease• Assessment of etiology is
important• Acute, anticipatory or delayed
Mannix, 2010
• Common in advanced disease• Assessment of etiology is
important• Acute, anticipatory or delayed
Mannix, 2010
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Causes of Nausea and Vomiting
Causes of Nausea and Vomiting
• Physiological (gastrointestinal, metabolic, central nervous system)
• Psychological• Disease related• Treatment related• Other
• Physiological (gastrointestinal, metabolic, central nervous system)
• Psychological• Disease related• Treatment related• Other
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Assessment of Nausea and Vomiting
Assessment of Nausea and Vomiting
• Physical exam• History• Lab values
• Physical exam• History• Lab values
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Pharmacologic Treatment of Nausea and Vomiting
Pharmacologic Treatment of Nausea and Vomiting
• Anticholinergics• Antihistamines• Steroids• Prokinetic agents• Other
• Anticholinergics• Antihistamines• Steroids• Prokinetic agents• Other
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Non-Drug Treatment of Nausea and Vomiting
Non-Drug Treatment of Nausea and Vomiting
• Distraction/relaxation• Dietary• Small/slow feeding• Invasive therapies
• Distraction/relaxation• Dietary• Small/slow feeding• Invasive therapies
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FatigueFatigue
• Subjective, multidimensional experience of exhaustion
• Commonly associated with many diseases
• Impacts all dimensions of quality of life
Anderson et al., 2010; Ferrell et al., 1996
• Subjective, multidimensional experience of exhaustion
• Commonly associated with many diseases
• Impacts all dimensions of quality of life
Anderson et al., 2010; Ferrell et al., 1996
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Causes of FatigueCauses of Fatigue
• Disease related• Psychological• Treatment related
• Disease related• Psychological• Treatment related
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Assessment of FatigueAssessment of Fatigue
• Subjective• Objective• Laboratory data
• Subjective• Objective• Laboratory data
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Treatment of FatigueTreatment of Fatigue
• Pharmacologic• Nonpharmacologic (rest, energy
conservation, involve physical therapy/occupational therapy)
Anderson et al., 2010
• Pharmacologic• Nonpharmacologic (rest, energy
conservation, involve physical therapy/occupational therapy)
Anderson et al., 2010
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DepressionDepression
• Ranges from sadness to suicidal• Often unrecognized and
undertreated• Distinguish normal vs. abnormal• Should not be dismissed
Pasacreta et al., 2010
• Ranges from sadness to suicidal• Often unrecognized and
undertreated• Distinguish normal vs. abnormal• Should not be dismissed
Pasacreta et al., 2010
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Causes of DepressionCauses of Depression
• Disease related• Psychological• Medication related• Treatment related
• Disease related• Psychological• Medication related• Treatment related
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Assessment of DepressionAssessment of Depression
• Situational factors/symptoms• Previous psychiatric history• Other factors (e.g. lack of
support system, pain)
Pasacreta et al., 2010
• Situational factors/symptoms• Previous psychiatric history• Other factors (e.g. lack of
support system, pain)
Pasacreta et al., 2010
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Example Questions for Depression AssessmentExample Questions for
Depression Assessment
• How have your spirits been lately?
• What do you see in your future?• What is the biggest problem you
are facing?
Pasacreta et al., 2010
• How have your spirits been lately?
• What do you see in your future?• What is the biggest problem you
are facing?
Pasacreta et al., 2010
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Suicide AssessmentSuicide Assessment
• Do you think life isn’t worth living?
• Have you thought about how you would kill yourself?
• Do you think life isn’t worth living?
• Have you thought about how you would kill yourself?
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Pharmacologic Interventions for Depression
Pharmacologic Interventions for Depression
• Antidepressants• Stimulants• Non-benzodiazepines• Steroids
• Antidepressants• Stimulants• Non-benzodiazepines• Steroids
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Non-Pharmacologic Interventions for Depression
Non-Pharmacologic Interventions for Depression
• Promote autonomy• Grief counseling• Draw on strengths• Use cognitive strategies
• Promote autonomy• Grief counseling• Draw on strengths• Use cognitive strategies
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AnxietyAnxiety
• Subjective feeling of apprehension• Often without specific cause• Categories of mild, moderate,
severe
• Subjective feeling of apprehension• Often without specific cause• Categories of mild, moderate,
severe
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Causes of AnxietyCauses of Anxiety
• Medications and substances• Uncertainty
Pasacreta et al., 2010
• Medications and substances• Uncertainty
Pasacreta et al., 2010
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Assessment of AnxietyAssessment of Anxiety
• Physical symptoms• Cognitive symptoms• Questions for assessment
APA, 2000
• Physical symptoms• Cognitive symptoms• Questions for assessment
APA, 2000
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Pharmacologic Interventions for Anxiety
Pharmacologic Interventions for Anxiety
• Antidepressants• Benzodiazepines/anticonvulsants• Neuroleptics• Non-benzodiazepines
• Antidepressants• Benzodiazepines/anticonvulsants• Neuroleptics• Non-benzodiazepines
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Non-pharmacologic Interventions for Anxiety
Non-pharmacologic Interventions for Anxiety
• Empathetic listening• Assurance and support• Concrete information/warning• Relaxation/imagery
• Empathetic listening• Assurance and support• Concrete information/warning• Relaxation/imagery
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Delirium/Agitation/Confusion
Delirium/Agitation/Confusion
• Delirium - Acute change in cognition/awareness
• Agitation - accompanies delirium
• Confusion - disorientation, inappropriate behavior, hallucinations
Heidrich & English, 2010
• Delirium - Acute change in cognition/awareness
• Agitation - accompanies delirium
• Confusion - disorientation, inappropriate behavior, hallucinations
Heidrich & English, 2010
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CausesCauses
• Infection• Medications• Hypoxemia• Bladder distention
• Infection• Medications• Hypoxemia• Bladder distention
Examples:Examples:
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AssessmentAssessment
• Physical exam• History• Spiritual distress• Other symptoms
Heidrich & English, 2010
• Physical exam• History• Spiritual distress• Other symptoms
Heidrich & English, 2010
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TreatmentTreatment
• Pharmacologic• Evaluate medications• Reorientation• Relaxation/distraction• Hydration
• Pharmacologic• Evaluate medications• Reorientation• Relaxation/distraction• Hydration
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WoundsWounds
• Patients at risk• Prevention as key• Patients at risk• Prevention as key
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Assessment of WoundsAssessment of Wounds
• Characteristics• Pain• Psychosocial• Caregivers
• Characteristics• Pain• Psychosocial• Caregivers
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Treatment of WoundsTreatment of Wounds
• Wound cleaning• Dressings• Provide analgesia• Seek consultation
• Wound cleaning• Dressings• Provide analgesia• Seek consultation
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SeizuresSeizures
• Definition• Causes– Infections– Trauma– HIV– Tumors– Medications– Metabolic imbalances
• Definition• Causes– Infections– Trauma– HIV– Tumors– Medications– Metabolic imbalances
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Assessment for SeizuresAssessment for Seizures
• Manifestations– Aura– Mental status changes– Sensory changes
• Physical exam• Labs
• Manifestations– Aura– Mental status changes– Sensory changes
• Physical exam• Labs
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Treatment for SeizuresTreatment for Seizures
• Limit trauma• Anticonvulsant treatments– Phenytoin– Phenobarbital– Lorazepam, diazepam
• Limit trauma• Anticonvulsant treatments– Phenytoin– Phenobarbital– Lorazepam, diazepam
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FeversFevers
• Definition• Causes– Infection– Tissue injury– Altered thermoregulation
• Definition• Causes– Infection– Tissue injury– Altered thermoregulation
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Assessment/Treatment of FeversAssessment/Treatment of Fevers
• Clinical– Flushing– Malaise/fatigue
• Rigors/shaking• Treatment– Antibiotics– Antipyretics– Cooling measures
• Clinical– Flushing– Malaise/fatigue
• Rigors/shaking• Treatment– Antibiotics– Antipyretics– Cooling measures
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MalariaMalaria
• High morbidity/mortality• Caused by a parasite• Use of prompt and effective
treatment WHO, 2010
• High morbidity/mortality• Caused by a parasite• Use of prompt and effective
treatment WHO, 2010
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Symptoms/Treatment of MalariaSymptoms/Treatment of Malaria
• Fever• Chills• Headache• Nausea/vomiting
• Fever• Chills• Headache• Nausea/vomiting
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Key RolesKey Roles
• Patient advocacy• Assessment• Pharmacologic treatments• Non-pharmacologic treatments• Patient/family teaching
• Patient advocacy• Assessment• Pharmacologic treatments• Non-pharmacologic treatments• Patient/family teaching
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ConclusionConclusion
• Multiple symptoms common• Coordination of care with
physicians and others• Use drug and nondrug treatment• Patient/family teaching and support
• Multiple symptoms common• Coordination of care with
physicians and others• Use drug and nondrug treatment• Patient/family teaching and support
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Give the answers to the following questions please
Give the answers to the following questions please
1. List the respiratory symptoms that occur in palliative care patients?
2. What Non-pharmacologic Interventions for Anxiety do you know?
3. What are the causes of Delirium?
1. List the respiratory symptoms that occur in palliative care patients?
2. What Non-pharmacologic Interventions for Anxiety do you know?
3. What are the causes of Delirium?
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