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CCEENNLLEEEnd-of-Life Nursing Education Consortium

International CurriculumInternational Curriculum

Symptom Management

Symptom Management

EE NN EE CCLL International CurriculumInternational Curriculum

Essential Elements of Symptom Management Essential Elements of

Symptom Management

• Ongoing assessment and evaluation

• Requires interdisciplinary teamwork

• Financial concerns (affordable options)

• Research is needed

Coyne et al., 2010

• Ongoing assessment and evaluation

• Requires interdisciplinary teamwork

• Financial concerns (affordable options)

• Research is needed

Coyne et al., 201022

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Symptoms and SufferingSymptoms and Suffering

• Symptoms create suffering and distress

• Need for interdisciplinary care• Determine clinical intervention– Benefit (s)– Burden (s)– Risk (s)

• Symptoms create suffering and distress

• Need for interdisciplinary care• Determine clinical intervention– Benefit (s)– Burden (s)– Risk (s)

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Common SymptomsCommon Symptoms• Respiratory– Dyspnea, cough

• GI– Anorexia/cachexia, constipation, diarrhea,

nausea/vomiting• Psychological– Depression, anxiety,

delirium/agitation/confusion• General/Systemic– Fatigue/weakness– Seizures– Fevers– Malaria

• Respiratory– Dyspnea, cough

• GI– Anorexia/cachexia, constipation, diarrhea,

nausea/vomiting• Psychological– Depression, anxiety,

delirium/agitation/confusion• General/Systemic– Fatigue/weakness– Seizures– Fevers– Malaria

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DyspneaDyspnea

• Distressing shortness of breath• Associated diseases

Dudgeon, 2010

• Distressing shortness of breath• Associated diseases

Dudgeon, 2010

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Causes of DyspneaCauses of Dyspnea

• Major pulmonary causes• Major cardiac causes• Major neuromuscular causes• Other causes

• Major pulmonary causes• Major cardiac causes• Major neuromuscular causes• Other causes

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Assessment of DyspneaAssessment of Dyspnea

• Use subjective report• Clinical assessment– Physical exam– Diagnostic tests

Dudgeon, 2010

• Use subjective report• Clinical assessment– Physical exam– Diagnostic tests

Dudgeon, 2010

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Treatment of DyspneaTreatment of Dyspnea

• Treating symptoms or underlying cause

• Pharmacologic treatments– Opioids– Bronchodilators– Diuretics– Other

Dudgeon, 2010; Jacobs, 2003

• Treating symptoms or underlying cause

• Pharmacologic treatments– Opioids– Bronchodilators– Diuretics– Other

Dudgeon, 2010; Jacobs, 2003

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Treatment of DyspneaTreatment of Dyspnea

• Nonpharmacologic– Oxygen– Counseling– Pursed lip breathing– Energy conservation– Fans, elevation– Other

Dudgeon, 2010; Kravits & Berenson, 2010

• Nonpharmacologic– Oxygen– Counseling– Pursed lip breathing– Energy conservation– Fans, elevation– Other

Dudgeon, 2010; Kravits & Berenson, 2010

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CoughCough

• Common symptom in advanced disease

• Causes pain, fatigue, insomnia

Dudgeon, 2010

• Common symptom in advanced disease

• Causes pain, fatigue, insomnia

Dudgeon, 2010

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Causes of CoughCauses of Cough

• Assess underlying cause (e.g. infection, sinusitis, reflux)

• Assess type of cough• Assess associated symptoms• Diagnostic tests may be needed

Dudgeon, 2010

• Assess underlying cause (e.g. infection, sinusitis, reflux)

• Assess type of cough• Assess associated symptoms• Diagnostic tests may be needed

Dudgeon, 2010

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Pharmacologic Interventions for Cough

Pharmacologic Interventions for Cough

• Suppressants/expectorants• Antibiotics• Steroids• Anticholinergics

• Suppressants/expectorants• Antibiotics• Steroids• Anticholinergics

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Non-Pharmacologic Interventions for Cough

Non-Pharmacologic Interventions for Cough

• Chest PT• Humidifier• Positioning

• Chest PT• Humidifier• Positioning

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Anorexia and CachexiaAnorexia and Cachexia

• Anorexia - loss of appetite, usually with decreased intake

• Cachexia - lack of nutrition and wasting

Wholihan & Kemp, 2010

• Anorexia - loss of appetite, usually with decreased intake

• Cachexia - lack of nutrition and wasting

Wholihan & Kemp, 2010

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Causes of Anorexia and Cachexia

Causes of Anorexia and Cachexia

• Disease related• Psychological• Treatment related

Fearon et al., 2010; Wholihan & Kemp, 2010

• Disease related• Psychological• Treatment related

Fearon et al., 2010; Wholihan & Kemp, 2010

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Assessment of Anorexia and Cachexia

Assessment of Anorexia and Cachexia

• Physical findings• Impact on function and quality of life• Calorie counts/daily weights• Lab tests• Skin breakdown

Wholihan & Kemp, 2010

• Physical findings• Impact on function and quality of life• Calorie counts/daily weights• Lab tests• Skin breakdown

Wholihan & Kemp, 2010

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Treatment of Anorexia and Cachexia

Treatment of Anorexia and Cachexia

• Dietary consultation• Medications• Parenteral/enteral nutrition• Odor control• Counseling

Earthman, 2002; MacDonald, 2003; Wholihan & Kemp, 2010

• Dietary consultation• Medications• Parenteral/enteral nutrition• Odor control• Counseling

Earthman, 2002; MacDonald, 2003; Wholihan & Kemp, 2010

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ConstipationConstipation

• Infrequent passage of stool• Frequent symptom in palliative

care• Prevention is key

• Infrequent passage of stool• Frequent symptom in palliative

care• Prevention is key

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Causes of ConstipationCauses of Constipation

• Disease related (e.g. obstruction, hypercalcemia, neurologic, inactivity)

• Treatment related (e.g. opioids, other meds)

• Disease related (e.g. obstruction, hypercalcemia, neurologic, inactivity)

• Treatment related (e.g. opioids, other meds)

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Assessment of ConstipationAssessment of Constipation

• Bowel history• Abdominal assessment• Rectal assessment• Medication review

Economou, 2010

• Bowel history• Abdominal assessment• Rectal assessment• Medication review

Economou, 2010

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Treatment of ConstipationTreatment of Constipation

• Medications• Dietary/fluids• Other approaches

Economou, 2010

• Medications• Dietary/fluids• Other approaches

Economou, 2010

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DiarrheaDiarrhea

• Frequent passage of loose, nonformed stool

• Effects (e.g. fatigue, caregiver burden, skin breakdown)

• Frequent passage of loose, nonformed stool

• Effects (e.g. fatigue, caregiver burden, skin breakdown)

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Causes of DiarrheaCauses of Diarrhea

• Disease related• Malabsorption• Concurrent diseases• Psychological• Treatment related

• Disease related• Malabsorption• Concurrent diseases• Psychological• Treatment related

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Assessment of DiarrheaAssessment of Diarrhea

• Bowel history• Medication review• Infectious processes

• Bowel history• Medication review• Infectious processes

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Treatment of DiarrheaTreatment of Diarrhea

• Treat underlying cause• Dietary modifications• Hydration• Pharmacologic agents

• Treat underlying cause• Dietary modifications• Hydration• Pharmacologic agents

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Nausea and VomitingNausea and Vomiting

• Common in advanced disease• Assessment of etiology is

important• Acute, anticipatory or delayed

Mannix, 2010

• Common in advanced disease• Assessment of etiology is

important• Acute, anticipatory or delayed

Mannix, 2010

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Causes of Nausea and Vomiting

Causes of Nausea and Vomiting

• Physiological (gastrointestinal, metabolic, central nervous system)

• Psychological• Disease related• Treatment related• Other

• Physiological (gastrointestinal, metabolic, central nervous system)

• Psychological• Disease related• Treatment related• Other

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Assessment of Nausea and Vomiting

Assessment of Nausea and Vomiting

• Physical exam• History• Lab values

• Physical exam• History• Lab values

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Pharmacologic Treatment of Nausea and Vomiting

Pharmacologic Treatment of Nausea and Vomiting

• Anticholinergics• Antihistamines• Steroids• Prokinetic agents• Other

• Anticholinergics• Antihistamines• Steroids• Prokinetic agents• Other

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Non-Drug Treatment of Nausea and Vomiting

Non-Drug Treatment of Nausea and Vomiting

• Distraction/relaxation• Dietary• Small/slow feeding• Invasive therapies

• Distraction/relaxation• Dietary• Small/slow feeding• Invasive therapies

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FatigueFatigue

• Subjective, multidimensional experience of exhaustion

• Commonly associated with many diseases

• Impacts all dimensions of quality of life

Anderson et al., 2010; Ferrell et al., 1996

• Subjective, multidimensional experience of exhaustion

• Commonly associated with many diseases

• Impacts all dimensions of quality of life

Anderson et al., 2010; Ferrell et al., 1996

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Causes of FatigueCauses of Fatigue

• Disease related• Psychological• Treatment related

• Disease related• Psychological• Treatment related

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Assessment of FatigueAssessment of Fatigue

• Subjective• Objective• Laboratory data

• Subjective• Objective• Laboratory data

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Treatment of FatigueTreatment of Fatigue

• Pharmacologic• Nonpharmacologic (rest, energy

conservation, involve physical therapy/occupational therapy)

Anderson et al., 2010

• Pharmacologic• Nonpharmacologic (rest, energy

conservation, involve physical therapy/occupational therapy)

Anderson et al., 2010

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DepressionDepression

• Ranges from sadness to suicidal• Often unrecognized and

undertreated• Distinguish normal vs. abnormal• Should not be dismissed

Pasacreta et al., 2010

• Ranges from sadness to suicidal• Often unrecognized and

undertreated• Distinguish normal vs. abnormal• Should not be dismissed

Pasacreta et al., 2010

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Causes of DepressionCauses of Depression

• Disease related• Psychological• Medication related• Treatment related

• Disease related• Psychological• Medication related• Treatment related

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Assessment of DepressionAssessment of Depression

• Situational factors/symptoms• Previous psychiatric history• Other factors (e.g. lack of

support system, pain)

Pasacreta et al., 2010

• Situational factors/symptoms• Previous psychiatric history• Other factors (e.g. lack of

support system, pain)

Pasacreta et al., 2010

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Example Questions for Depression AssessmentExample Questions for

Depression Assessment

• How have your spirits been lately?

• What do you see in your future?• What is the biggest problem you

are facing?

Pasacreta et al., 2010

• How have your spirits been lately?

• What do you see in your future?• What is the biggest problem you

are facing?

Pasacreta et al., 2010

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Suicide AssessmentSuicide Assessment

• Do you think life isn’t worth living?

• Have you thought about how you would kill yourself?

• Do you think life isn’t worth living?

• Have you thought about how you would kill yourself?

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Pharmacologic Interventions for Depression

Pharmacologic Interventions for Depression

• Antidepressants• Stimulants• Non-benzodiazepines• Steroids

• Antidepressants• Stimulants• Non-benzodiazepines• Steroids

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Non-Pharmacologic Interventions for Depression

Non-Pharmacologic Interventions for Depression

• Promote autonomy• Grief counseling• Draw on strengths• Use cognitive strategies

• Promote autonomy• Grief counseling• Draw on strengths• Use cognitive strategies

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AnxietyAnxiety

• Subjective feeling of apprehension• Often without specific cause• Categories of mild, moderate,

severe

• Subjective feeling of apprehension• Often without specific cause• Categories of mild, moderate,

severe

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Causes of AnxietyCauses of Anxiety

• Medications and substances• Uncertainty

Pasacreta et al., 2010

• Medications and substances• Uncertainty

Pasacreta et al., 2010

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Assessment of AnxietyAssessment of Anxiety

• Physical symptoms• Cognitive symptoms• Questions for assessment

APA, 2000

• Physical symptoms• Cognitive symptoms• Questions for assessment

APA, 2000

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Pharmacologic Interventions for Anxiety

Pharmacologic Interventions for Anxiety

• Antidepressants• Benzodiazepines/anticonvulsants• Neuroleptics• Non-benzodiazepines

• Antidepressants• Benzodiazepines/anticonvulsants• Neuroleptics• Non-benzodiazepines

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Non-pharmacologic Interventions for Anxiety

Non-pharmacologic Interventions for Anxiety

• Empathetic listening• Assurance and support• Concrete information/warning• Relaxation/imagery

• Empathetic listening• Assurance and support• Concrete information/warning• Relaxation/imagery

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Delirium/Agitation/Confusion

Delirium/Agitation/Confusion

• Delirium - Acute change in cognition/awareness

• Agitation - accompanies delirium

• Confusion - disorientation, inappropriate behavior, hallucinations

Heidrich & English, 2010

• Delirium - Acute change in cognition/awareness

• Agitation - accompanies delirium

• Confusion - disorientation, inappropriate behavior, hallucinations

Heidrich & English, 2010

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CausesCauses

• Infection• Medications• Hypoxemia• Bladder distention

• Infection• Medications• Hypoxemia• Bladder distention

Examples:Examples:

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AssessmentAssessment

• Physical exam• History• Spiritual distress• Other symptoms

Heidrich & English, 2010

• Physical exam• History• Spiritual distress• Other symptoms

Heidrich & English, 2010

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TreatmentTreatment

• Pharmacologic• Evaluate medications• Reorientation• Relaxation/distraction• Hydration

• Pharmacologic• Evaluate medications• Reorientation• Relaxation/distraction• Hydration

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WoundsWounds

• Patients at risk• Prevention as key• Patients at risk• Prevention as key

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Assessment of WoundsAssessment of Wounds

• Characteristics• Pain• Psychosocial• Caregivers

• Characteristics• Pain• Psychosocial• Caregivers

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Treatment of WoundsTreatment of Wounds

• Wound cleaning• Dressings• Provide analgesia• Seek consultation

• Wound cleaning• Dressings• Provide analgesia• Seek consultation

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SeizuresSeizures

• Definition• Causes– Infections– Trauma– HIV– Tumors– Medications– Metabolic imbalances

• Definition• Causes– Infections– Trauma– HIV– Tumors– Medications– Metabolic imbalances

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Assessment for SeizuresAssessment for Seizures

• Manifestations– Aura– Mental status changes– Sensory changes

• Physical exam• Labs

• Manifestations– Aura– Mental status changes– Sensory changes

• Physical exam• Labs

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Treatment for SeizuresTreatment for Seizures

• Limit trauma• Anticonvulsant treatments– Phenytoin– Phenobarbital– Lorazepam, diazepam

• Limit trauma• Anticonvulsant treatments– Phenytoin– Phenobarbital– Lorazepam, diazepam

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FeversFevers

• Definition• Causes– Infection– Tissue injury– Altered thermoregulation

• Definition• Causes– Infection– Tissue injury– Altered thermoregulation

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Assessment/Treatment of FeversAssessment/Treatment of Fevers

• Clinical– Flushing– Malaise/fatigue

• Rigors/shaking• Treatment– Antibiotics– Antipyretics– Cooling measures

• Clinical– Flushing– Malaise/fatigue

• Rigors/shaking• Treatment– Antibiotics– Antipyretics– Cooling measures

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MalariaMalaria

• High morbidity/mortality• Caused by a parasite• Use of prompt and effective

treatment WHO, 2010

• High morbidity/mortality• Caused by a parasite• Use of prompt and effective

treatment WHO, 2010

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Symptoms/Treatment of MalariaSymptoms/Treatment of Malaria

• Fever• Chills• Headache• Nausea/vomiting

• Fever• Chills• Headache• Nausea/vomiting

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Key RolesKey Roles

• Patient advocacy• Assessment• Pharmacologic treatments• Non-pharmacologic treatments• Patient/family teaching

• Patient advocacy• Assessment• Pharmacologic treatments• Non-pharmacologic treatments• Patient/family teaching

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ConclusionConclusion

• Multiple symptoms common• Coordination of care with

physicians and others• Use drug and nondrug treatment• Patient/family teaching and support

• Multiple symptoms common• Coordination of care with

physicians and others• Use drug and nondrug treatment• Patient/family teaching and support

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Give the answers to the following questions please

Give the answers to the following questions please

1. List the respiratory symptoms that occur in palliative care patients?

2. What Non-pharmacologic Interventions for Anxiety do you know?

3. What are the causes of Delirium?

1. List the respiratory symptoms that occur in palliative care patients?

2. What Non-pharmacologic Interventions for Anxiety do you know?

3. What are the causes of Delirium?

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