aspirin mindmap
Post on 20-Apr-2015
36 Views
Preview:
DESCRIPTION
TRANSCRIPT
Organic Molecules and Medicine
Aspirin
from SALICILIN
leaves & barks of
Willow trees
Human body
converts it to
Salicylic Acid
active substance
reduce fever
painkiller
more effective
acidic
unpleasant taste
irritates lining
Felix Hoffmanmodified salicylic acid
coal tarcoal heated with no air
replaced the -O-Hwith ester functional group
becomes ACETYLSALICYLIC ACID
Acetysalicylic Acidesterification process
with ethanolslow reaction
low yield
ethanoic anhydridefaster reaction
higher yield
seperatedpurified
packaged tablet Tastelessless irritating to liningactive
after hydrolysisin stomach
alkaline conditions
an active salicylic acid
Soluble Aspirin
not pure
replace -COOHsodium salt becomes ion
more soluble
=Buffered aspirin
Polyaspirin via condensationsalicylic acid + suberic acidprevent pain
largerenter bloodstram hydrolyse salicylic acid
no stomach irritationAdvantage
controlled release painkiller breaks down slowlysimiliar to POLYESTERS
can stitch woundsfight pain & inflammation where needed
plastic coating for injured bonepromote bone growth
heal & ease pain
top related