Advanced Core DecompressionThe Comprehensive Solution

™ and ® denote Trademarks and Registered Trademarks of Wright Medical Group N.V. or its affiliates. ©2016 Wright Medical Group N.V. or its affiliates. All Rights Reserved. 009783A 04-Mar-2014

Instrumentation and Grafting

Treatment of Avascular Necrosis (AVN) of the hip can be a life-altering event,particularly for younger, active patients that may face a prosthetic jointarthroplasty. Core decompressions have been used with success in ficatstage I and II AVN.1,2,3,4

The Advanced Core Decompression System includes the reusable X-REAM® Percutaneous Expandable Reamer that allows optimized debridement when used in conjunction with a standard core decompression, a single-use, disposable instrument kit (sold separately) designed to efficiently facilitate a standard core decompression, and PRO-DENSE® Injectable Graft for backfilling the surgically-created defect.

These instruments have been carefully selected and tested to simplify the technique for efficiency and consistency and to possibly provide a more cost effective outcome.5

All-inclusive, single use procedure kits for standard core decompressions

PRO-DENSE® and PRO-STIM® Core Decompression Kits

9.0mm Drill Bit

Tissue Protector

TampCurette3.2mm Fluted

Guidewire

Working Cannula & Obturator

The Comprehensive Solutionfor Core Decompression

Advanced Core Decompression: Debride more through the same hole with the X-REAM® Expandable Reamer

X-REAM® Percutaneous Expandable Reamer

Predicatable Bone Regeneration

PRO-DENSE® Injectable Regenerative Graft has a unique triphasic resorption profile that provides an ideal environment for the direct deposition of bone by binding growth factors6 and by providing a slow-resorbing matrix that supports healing across the defect.

Accelerate Healing7

PRO-STIM® Injectable Inductive Graft is the next step in composite grafting technology. Built on the PRO-DENSE® material platform as a combination of calcium sulfate and calcium phosphate, PRO-STIM® graft adds demineralized bone matrix (DBM) for osteoinductive factors to speed the healing and remodeling process.

Note: Published data suggests that core decompressions in later stage AVN (Stage IIB, III, or IV) may result in poorer outcomes. The included PRO-DENSE® or PRO-STIM® Graft should not be used in late stage AVN where the graft may be subject to loading.

PRO-STIM® Injectable Inductive Graft

PRO-DENSE® Injectable Regenerative Graft

SetsResorbsInduces Bone Formation

AccelerateHealing7

Osteonecrosis: Bilateral Hips | Forty-Two Year-Old Female with idiopathic AVN of both hips (both Stage II AVN)7

Images courtesy of Robert Heck, MD Campbell Clinic, Memphis, TN

Post-op: RightPre-op MRI Post-op: Left 1 Year Post-op: Right 1 Year Post-op: Left

Over 4 years of clinical performance in challenging applications

Synthetic, Hard Setting Option

DBM-Containing, Setting Option

REFERENCES 1. Bozic KJ, et al. Survivorship analysis of hips treated with core

decompression for nontraumatic osteonecrosis of the femoral head. J. Bone Joint Surg. Am. 1999; 81-A(2): 200-209.

2. Lavernia CJ, et al. Core decompression in a traumatic osteonecrosis of the hip. J. Arthroplasty 2000; 15(2): 171-178.

3. Simank HG, et al. Comparison of results of core decompression on intertrochanteric osteotomy for nontraumatic osteonecrosis of the femoral head using cox regression and survivorship analysis. J. Arthroplasty 2001; 16(6): 790-794.

4. Steinberg ME, et al. Core decompression with bone grafting for osteonecrosis of the femoral head. Clin. Orthop. 2001; 386: 71-78.

5. SooHoo NF, et al. Cost-effectiveness analysis of core decompression. J Arthroplasty 2006; 21(5):670-681.

6. Growth factor binding based on in vitro data of BMP-2 and VEGF. Data on file at Wright.

7. All claims based on a canine critical size defect model. The accelerated rate of healing of the PRO-DENSE® treated defects compared to those treated with autograft is principally evident by the higher density bone and superior average mechanical properties at 13 weeks. It is unknown how results from the canine model compare with clinical results in humans. Data on file at Wright.

Ordering InformationX-REAM® Percutaneous Expandable Reamer

1000-KIT2 WRIGHT EXPRESS® Kit20BL1200 X-REAM® Blade

Core Decompression Kits

87SR-CK15 PRO-DENSE® Core Decompression Kit – 15cc86SR-CK15 PRO-STIM® Core Decompression Kit – 15cc

PRO-DENSE® Injectable Regenerative Graft

87SR-0404 4cc87SR-0410 10cc87SR-0420 20cc

PRO-STIM® Injectable Inductive Graft

86SR-0404 4cc68SR-0410 10cc86SR-0420 20cc

™ and ® denote Trademarks and Registered Trademarks of Wright Medical Group N.V. or its affiliates. ©2016 Wright Medical Group N.V. or its affiliates. All Rights Reserved. 009783A 04-Mar-2014

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