TABLE 1. Research interest by FDA Race category

FDA Race Category

S380 Abstracts

N

% Research Interest OR 95% CI

Caucasian

550 75% 1 Asian 252 55% 0.41 (0.30; 0.56) Black or African-

American

23 74% 0.93 (0.36; 2.41)

Latino/Hispanic

55 78% 1.06 (0.55; 2.04) American Indian or

Alaska Native

2 100%

Native Hawaiian or OtherPacific Islander

1

100%

Other

9 78% 1.15 (0.24; 5.60) Unknown 77 74% 0.94 (0.54; 1.61) Total 969 70%

Of the sub-categories, patients self-identifying as Middle Eastern wereleast willing to be contacted (45%), and of all Asian sub-categories thoseof Japanese origin were least willing to be contacted (40%). African-Amer-icans and Hispanic/Latino had similar responses to Caucasians about re-search interest. Age and gender were not statistically significant in theregression models and patients born outside the US were equally likely tobe willing to be contacted.

CONCLUSIONS: There are significant differences among patients intheir willingness to be contacted about research. Patients self-reportingAsian or Middle Eastern are much less willing to consider research thanCaucasian patients, regardless of county of birth. These findings empha-size the racial disparity in medical research participation and highlightthe need to develop strategies to encourage diverse participation in medi-cal research.

Supported by: None.

P-809

ADNEXAL TORSION: EVALUATION OF RISK FACTORS ANDMODE OF TREATMENT. Z. Tsafrir, E. Solomon, I. Levin, J. Lessing,F. M. D. Azem. Obstetric & Gynecology, Tel Aviv Sourasky Medical Center,Kiriat Ono, Israel; Sackler Faculty of Medicine, Tel Aviv University, Herze-lya, Israel.

OBJECTIVE: To assess risk factors, clinical findings and mode of treat-ment in women with surgically proven ovarian torsion.

DESIGN: A retrospective case review of surgically proven ovarian torsionat the Tel-Aviv Medical Center between 1997-2007.

MATERIALS AND METHODS: All patients who were operated forproven adnexal torsion between 1997-2007. Statistical analysis was per-formed with the use of SASS statistical software.

RESULTS: Ninety one cases were identified. Median age was 29. Twowere postmenopausal, 37 underwent In Vitro Fertilization/ Embryo Trans-plant (IVF/ET), 33 were pregnant with a median gestational age of 7weeks. The most common risk factor at presentation was a history of ovar-ian cyst (14%). Sixty two cases (68%) were seen first in the gynecologicalER. The main clinical features included: sudden pain (77%), non-constantpain (85%), nausea/vomiting (33%). Median symptom duration was 4hours. In 40% of cases an advanced imaging studies (Dopler US, CT)were done. 43% of dopler examinations demonstrated normal arterial andvenous flow. Median time from admission to diagnosis was 6 hours.Time to diagnoses was significantly longer when patients underwent doplerUS (mean of 17.2 hr’s vs.6.3 hr’s, p¼0.003). In addition, Patients who wereexamined first in the general ER, had a significant delay in diagnosis, com-paring to those who presented first to the gynecological ER (mean of 19.5hr’s and 8 hr’s respectively, p¼0.04). Laparoscopic procedures were con-ducted in 80 cases (88%), laparoscopy converted to laparotomy in 3 cases(3.2%) and initial laparotomy in 8 cases (8.8%). None of the cases was ma-lignant. Concerning the treatment, 35 cases (38.5%) underwent detorsionprocedure, in 42 cases (46%) a combined detorsion and cystectomy or fen-estration were performed and 4 patients (4.5%) underwent either adnexec-tomy or Bilateral Salpingo-Oophorectomy (BSO), 2 of which werepostmenopausal.Adnexal fixation was conducted in 10 cases (11%). Ninecases of recurrent torsion were documented, following fixation. Medianstay in hospital was 4 days.

CONCLUSIONS: Two main sub-groups at risk for ovarian torsion weredocumented: a) IVF/ET, b) pregnant women during their 1st trimester. Com-

paring to other researches, our study shows an extremely short time intervalfrom admission to diagnosis. Although imaging studies helped in diagnosisof ovarian cysts, mostly it caused a delay in the surgical procedure. Further-more, fewer cases of adnexectomies were reported (4.4%).

Supported by: None.

P-810

ADVANCED REPRODUCTIVE TECHNOLOGIES FOR HIV-POSI-TIVE INDIVIDUALS AND COUPLES IN CANADA. M. H. Yudin,H. M. Shapiro, M. R. Loutfy. Obstetrics and Gynecology, St. Michael’s Hos-pital, University of Toronto, Toronto, ON, Canada; Obstetrics and Gynecol-ogy, Mt. Sinai Hospital, University of Toronto, Toronto, ON, Canada;Medicine, Women’s College Hospital, University of Toronto, Toronto, ON,Canada.

OBJECTIVE: To determine the types of advanced reproductive technolo-gies (ART) that are available and would be offered at fertility clinics in Can-ada for HIV-infected individuals and couples.

DESIGN: A survey was sent to all fertility clinics in Canada by email orfax. The survey contained questions regarding the availability of services (in-vestigations and treatment) for HIV-positive men and women for infertilityand/or risk reduction in achieving pregnancy. Non-responders were re-con-tacted twice.

MATERIALS AND METHODS: Results were tabulated and the propor-tion of clinics providing services was calculated.

RESULTS: There are a total of 28 fertility clinics across eight Canadianprovinces, and completed surveys were received from 20 of 28 (71%) clinicsin all eight provinces. 4/20 (20%) reported being unwilling to see HIV-pos-itive individuals, and sixty per cent (12/20) of clinics had seen at least oneHIV-positive male or female within the previous year. The most commontype of ART available was intrauterine insemination (IUI) for couples inwhich the female partner was HIV-positive, with 12/20 (60%) clinics offeringthis service. Less commonly available services included sperm washing forHIV-positive males (6/20 clinics, 30%) and in vitro fertilization (IVF) forcouples with an HIV-positive female (4/20 clinics, 20%). 8/20 (40%) ofclinics were willing to offer some combination of ART to HIV-infected cou-ples. Sixty per cent (12/20) of clinics were willing to offer donor sperm tosingle HIV-positive women. Finally, a small number of clinics used separatetimes of the day or week (3/20, 15%) or had separate facilities (2/20, 10%) tohandle potentially infectious specimens.

CONCLUSIONS: In this national survey of fertility clinics across Canada,ART were offered by a limited number of facilities. The most commonlyavailable service was IUI, with sperm washing and IVF being more difficultto access. Increased availability of these services is important for HIV posi-tive men and women to assist with pregnancy planning.

Supported by: AIDS Bureau, Ontario Ministry of Health and Long-TermCare.

P-811

ASSOCIATION OF ENDOMETRIAL THICKNESS AND PATTERNON PREGNANCY OUTCOME IN SUPEROVULATION CYCLES.A. D. Eyvazzadeh, S. Beck, E. Rillamas-Sun, M. Moravek, M. Lanham,D. I. Lebovic. Obstetrics and Gynecology, University of Michigan, Ann Ar-bor, MI; Department of Epidemiology, University of Michigan, School ofPublic Health, Ann Arbor, MI.

OBJECTIVE: Limited data exist concerning the relationship between en-dometrial thickness and pregnancy outcome in superovulation cycles. Thisstudy sought to determine whether endometrial thickness and pattern as ob-served by transvaginal sonography was predictive of pregnancy outcome orrelated to first-trimester bleeding in those who conceived with superovulation.

DESIGN: Retrospective analysis of endometrial thickness and pattern forpatients who became pregnant while undergoing infertility treatment at theUniversity of Michigan.

MATERIALS AND METHODS: Between 1999-2007, 162 pregnancieswere identified. Demographic data, infertility diagnosis, treatment type,bleeding history, endometrial thickness/texture on day of hCG, and

Vol. 90, Suppl 1, September 2008