a concise synthesis of 8-oxoberberine and oxychelerythrine, natural isoquinoline alkaloids through...

2007 Alkaloids U 0600 A Concise Synthesis of 8-Oxoberberine and Oxychelerythrine, Natural Isoquino- line Alkaloids Through Biomimetic Synthetic Way. — Berberine is used in the tra- ditional oriental medicine. The substance exhibits antidiabetic, anticancer and anti- microbial activities as well as a strong cholesterol-lowering effect. Chelerythrine shows antitumor and protein kinase C inhibitory activities. — (LE, T. N.; CHO*, W.-J.; Bull. Korean Chem. Soc. 27 (2006) 12, 2093-2096; Coll. Pharm., Chonnam Natl. Univ., Gwangju 500-757, S. Korea; Eng.) — K. Woydowski 19- 176

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Page 1: A Concise Synthesis of 8-Oxoberberine and Oxychelerythrine, Natural Isoquinoline Alkaloids Through Biomimetic Synthetic Way

2007

AlkaloidsU 0600 A Concise Synthesis of 8-Oxoberberine and Oxychelerythrine, Natural Isoquino-

line Alkaloids Through Biomimetic Synthetic Way. — Berberine is used in the tra-ditional oriental medicine. The substance exhibits antidiabetic, anticancer and anti-microbial activities as well as a strong cholesterol-lowering effect. Chelerythrine shows antitumor and protein kinase C inhibitory activities. — (LE, T. N.; CHO*, W.-J.; Bull. Korean Chem. Soc. 27 (2006) 12, 2093-2096; Coll. Pharm., Chonnam Natl. Univ., Gwangju 500-757, S. Korea; Eng.) — K. Woydowski

19- 176

ISOQUINOLINE SYNTHESES

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