a-1d diabetes an update on american diabetes association guidelines

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    Diabetes: Updates on ADA Guidelines

    January 2012

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    Objectives

    State the standards of diabetic care put forth by the

    American Diabetes Association Discuss the co-morbidities of diabetes, the standards

    of care that influence their management andstrategies to achieve the goals of care

    Discuss ways correctional institutions can improve

    compliance with the recommendations for diabetic

    care in correctional institutions

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    Diabetes Facts

    Diabetes affects 25.8 million people in the United

    States 18.8 million diagnosed

    7 million undiagnosed

    Diabetes is the leading cause of kidney failure, non-

    traumatic lower limb amputations, and new cases ofblindness among adults in the United States

    Diabetes is a major cause of heart disease and stroke

    Diabetes is the seventh leading cause of death in theUnited States

    Source: CDC Fact Sheet, 2011

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    Diabetes Facts

    Every 1% drop in A1c blood test results can decrease

    the risk of microvascular complications of diabetesby 40%

    Blood pressure control reduces the risk ofcardiovascular disease (heart disease or stroke)among people with diabetes by 33% to 50%, and the

    risk of microvascular complications by 33%. In general, for every 10 mmHg reduction in systolic

    blood pressure, the risk for any complications relatedto diabetes is reduced by 12%.

    Reducing diastolic blood pressure from 90 mmHg to80 mmHg in people with diabetes reduces the risk ofmajor cardiovascular events by 50%.

    Source: CDC Fact Sheet, 2011

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    Diabetes Facts

    Improved control of LDL cholesterol can reduce

    cardiovascular complications by 20% to 50%. Detecting and treating diabetic eye disease can reduce

    development of severe vision loss by an estimated 50%to 60%.

    Comprehensive foot care programs risk assessment,

    foot care education and preventive therapy, treatment offoot problems and referral to specialists can reduceamputation rates by 45% to 85%.

    Detecting and treating early diabetic kidney disease bylowering blood pressure can reduce the decline in kidney

    function by 30% to 70%. ACEIs and ARBs are moreeffective than other antihypertensive medications inreducing the decline in kidney function

    Source: CDC Fact Sheet, 2011

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    Magnitude of Complications

    Diabetic

    Retinopathy

    Leading cause

    of blindnessin working age

    adults

    Diabetic

    Nephropathy

    Leading cause ofend-stage renal disease

    Stroke

    Cardiovascular

    Disease

    2-fold to 4-foldincrease incardiovascularmortalityand stroke

    Diabetic

    Neuropathy

    Leading cause of nontraumatic

    lower extremity amputationsNational Diabetes Information Clearinghouse. At:http://www.niddk.nih.gov/health/diabetes/pubs/dmstats/dmstats.htm

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    Guidelines 2011

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    Diabetes Disease Management

    Intake Medical Assessment

    Complete medical historyand intake physical exam bylicensed health professionalin a timely manner

    Insulin-dependent diabeticsshould have capillary bloodglucose (CBG) within 1 to 2hours of arrival

    Medications and medical

    nutrition therapy (MNT)continued withoutinterruption

    Screening for Diabetes

    Evaluate for diabetes risk

    factors at intake physical and

    as appropriate thereafter

    BMI 25 with history of

    hypertension or hyperlipidemia BMI 25 and additional risk

    factors or age > 45 with or

    without risk factors

    If pregnant, risk assessment

    for gestational diabetesmellitus (GDM) at first pre-

    natal visit

    Re-screen at 24-28 weeks

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    Criteria for Testing for Diabetes

    Adults who are overweight (BMI 25) and have additional riskfactors: Physical inactivity

    First-degree relative with diabetes

    High-risk race/ethnicity

    Women who delivered a baby weighing > 9 lb or were diagnosed withGDM

    Hypertension on therapy for hypertension HDL cholesterol < 35 mg/dl and/or triglyceride > 250 mg/dl

    Women with polycystic ovarian syndrome (PCOS)

    A1c > 5.7% on previous testing

    History of cardiovascular disease

    Other clinical conditions associated with insulin resistance If results are normal, repeat testing at three-year intervals or

    more frequently depending on initial results and risk status

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    Criteria for Diagnosis of Diabetes

    A1c 6.5% - NEW!

    OR

    Fasting plasma glucose (FPG) 126 mg/dl (7.0

    mmol/l) no caloric intake for at least 8 hours

    OR Two-hour plasma glucose 200 mg/dl (11.1 mmol/l)

    during an oral glucose tolerance test (OGTT)

    OR

    A random plasma glucose 200 mg/dl (11.1 mmol/l)

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    Goals of Treatment - Glucose

    A1c < 7.0%

    Pre-prandial CBG 70 130 mg/dl Peak postprandial CBG < 180 mg/dl

    Less stringent A1c goals may be appropriate for patients

    with History of severe hypoglycemia, limited life expectancy,

    advanced microvascular or macrovascular complications,extensive co-morbid conditions

    Those with longstanding diabetes in whom general goal isdifficult to attain despite education, glucose monitoring andeffective doses of multiple glucose lowering agents includinginsulin

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    Correlation of A1c with Estimated Average Glucose

    Mean plasma glucose

    A1C (%) mg/dl mmol/l

    6 126 7.0

    7 154 8.6

    8 183 10.2

    9 212 11.8

    10 240 13.4

    11 269 14.9

    12 298 16.5

    ADA. V. Diabetes Care. Diabetes Care 2011;34(suppl 1):S18. Table 9.

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    Components of Management

    Blood sugar control

    Patient education Nutrition counseling

    Medication

    Physical activity

    Foot care

    Retinopathy

    Nephropathy

    Cardiac

    Lipid Management

    Smoking cessation

    Vaccines

    Transfer and discharge

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    Blood Sugar Control

    Goal is A1c < 7.0%

    Chronic care clinic for management

    Every 3 6 months if A1c consistently < 7.0%

    Every 2 3 months if A1c is 7.0% - 9.0%

    Every month if A1c > 9.0% until better control is achieved Achieving good control requires:

    Patient education and motivation

    Effective combination of medications

    Appropriate diet and compliance

    Daily blood glucose monitoring

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    Patient Education

    Nutrition including commissary choices

    Medication

    Empowerment for self-management

    Choice

    Control Consequences

    Peer groups

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    Nutritional Counseling

    Individuals who have diabetes or pre-diabetes should

    receive individualized medical nutrition therapy Include counseling regarding the better choices

    from items available in the commissary

    Use commissary purchase list as an additional

    opportunity for education and counseling Encourage weight loss if BMI 25

    Education regarding portion control

    Think about implementing a heart healthy diet forALL inmates benefits everyone and reduces needfor special medical diets

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    Medication

    Formularies should provide access to usual and

    customary oral medications and insulins to treatdiabetes and related conditions

    Patients should have access to medications at dosing

    frequencies that are consistent with their treatment

    plan and direction

    Correctional institutions and police lock-ups should

    implement policies and procedures to diminish the

    risk of hypo- and hyperglycemia during off-site travel

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    Physical Activity

    Exercise 150 minutes/week of moderate intensity

    aerobic activity Almost everyone can walk

    If there isnt sufficient place to walk on the grounds,consider setting aside gym time for walking around

    the court or running laps Exercise does not mean everyone has to work out in

    the weight room

    In absence of contraindications, people with type 2diabetes should be encouraged to perform resistancetraining three times per week

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    Foot care

    Instruct the patient with diabetes to examine his/her

    feet daily and report to medical at the first sign ofbreakdown

    Examine the patients feet at every encounter

    Annual comprehensive foot exam to includeinspection, assessment of pulses, testing for loss of

    protective sensation (monofilament, pinprick, etc.)

    Multidisciplinary approach at the first sign of foot

    ulcer and for those with high-risk feet

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    Monofilament Testing

    Upper panel

    To perform the 10-gmonofilament test, place thedevice perpendicular to theskin, with pressure applieduntil the monofilamentbuckles

    Hold in place for 1 secondand then release

    Lower panel

    The monofilament testshould be performed at thehighlighted sites while thepatients eyes are closed

    Boulton AJM, et al. Diabetes Care.2008;31:1679-1685

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    Retinopathy

    Initial dilated retinal and comprehensive eye exam by

    an ophthalmologist or optometrist shortly afterdiagnosis

    Subsequent examinations annually

    High quality fundus photographs can detect most

    clinically significant diabetic retinopathy.Interpretation should be performed by a trained eyecare provider. This is not a substitute for acomprehensive eye exam.

    Eye exam in the first trimester with close follow upthroughout pregnancy and for one year postpartum

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    Nephropathy

    Annual test to assess urine albumin excretion in type 1

    diabetic patients with diabetes duration of 5 years Annual test to assess urine albumin excretion in all type 2

    diabetic patients starting at diagnosis

    Serum Creatinine at least annually in all adults with

    diabetes regardless of the degree of urine albuminexcretion

    GFR at least annually to stage level of chronic kidneydisease

    If micro- or macroalbuminuria, treat with ACE or ARB(contraindicated in pregnancy)

    Reduction of protein intake if patient has CKD

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    Stages of Chronic Kidney Disease

    Stage Description

    GFR (ml/min per

    1.73 m

    2

    bodysurface area)

    1 Kidney damage* with normal or

    increased GFR

    90

    2 Kidney damage* with mildly decreased

    GFR

    6089

    3 Moderately decreased GFR 3059

    4 Severely decreased GFR 1529

    5 Kidney failure

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    Cardiovascular Disease

    BP at every encounter goal is < 130/80

    If not at goal: Lifestyle therapy for maximum of 3 months if systolic 130

    139 or diastolic 80 89

    Weight loss if overweight

    Dietary Approaches to Stop Hypertension (DASH) diet

    Increased physical activity

    Moderation of alcohol intake

    If systolic 140 or diastolic 90 at diagnosis or follow up,begin pharmacologic therapy in addition to lifestyle

    therapyACE or ARB and diuretic (thiazide if GFR 30 andloop if GFR < 30)

    Monitor kidney function and serum potassium levels

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    Antiplatelet Agents

    Consider aspirin therapy (75 to 162 mg/day) as a primaryprevention strategy in those with type 1 and type 2 diabetesat increased cardiovascular risk (10-yr risk > 10%)

    Includes men > 50 years or women > 60 years with at least oneadditional major risk factor (family history of CVD, HTN, smoking,dyslipidemia, albuminuria)

    ASA not recommended for those at low cardiovascular risk

    Use aspirin as a secondaryprevention strategy in patientswith diabetes and history of CVD

    For patients with CVD and documented ASA allergy,clopidogrel (75 mg/day) should be used

    Combination therapy with ASA and clopidogrel is reasonablefor up to one year after an acute coronary syndrome

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    Lipid Management

    Fasting lipid profile at least annually

    Goal is LDL-C < 100 mg/dl

    Goal for those with CVD is < 70 mg/dl

    If goal is not met on maximum drug therapy, reduction of30% - 40% from baseline is an alternative goal

    Lifestyle therapy for all diabetic patients Statin therapy should be added to lifestyle therapy,

    regardless of lipid levels, for diabetic patients:

    With overt CVD

    Without CVD who are over the age of 40 and have one or moreother CVD risk factor

    Statin therapy is contraindicated in pregnancy

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    Smoking Cessation

    Advise all patients not to smoke

    Include smoking cessation counseling and otherforms of treatment as a routine component of

    diabetes care

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    Immunizations

    Provide an influenza vaccine annually to all diabetic

    patients 6 months of age Administer pneumococcal polysaccharide vaccine to

    all diabetic patients 2 years

    One-time revaccination recommended for those > 64

    years previously immunized at < 65 years ifadministered 5 years ago

    Other indications for repeat vaccination:

    Nephrotic syndrome

    Chronic renal disease

    Immunocompromised states

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    Transfer and Discharge

    For all inter-institutional transfers, complete a

    medical transfer summary to be transferred with thepatient

    Diabetes supplies and medication should accompany

    the patient during transfer

    Begin discharge planning with adequate lead time to

    ensure continuity of care and facilitate entry into

    community diabetes care

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    Diabetic Emergencies

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    Diabetes Emergencies

    People experiencing diabetes emergencies may:

    Appear intoxicated

    Appear under the influence of drugs

    Appear uncooperative

    When in doubt, ask the person or his/her

    companions if the person has diabetes and check for

    medical identification bracelet, necklace, or card

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    Warning Signs that Require Action

    Hypoglycemia

    Sweating

    Shakiness

    Anxiety

    Confusion

    Difficulty speaking Uncooperative behavior

    Paleness

    Irritability

    Dizziness

    Inability to swallow

    Seizure

    Loss of consciousness

    Hyperglycemia

    Flushed skin

    Labored breathing

    Confusion

    Cramps Very weak

    Sweet breath

    Nausea

    Loss of consciousness

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    Emergency Treatment

    Hypoglycemia

    Give can sugared (non-

    diet) soda unless the

    person cannot swallow

    Obtain immediate

    assistance from a qualifiedhealth care professional

    Continue to give sugar

    source every 15 minutes

    until blood sugar > 70

    If unconscious, give

    Glucagon or D50 IV

    Hyperglycemia

    Give access to water

    Give access to bathroom

    Give access to medication

    Obtain immediateassistance from a qualified

    health care professional

    Give regular NOT LONG-

    ACTINGinsulin

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    How to Ensure Safety of Patients with Diabetes

    Identification Promptly identify patients with diabetes and ensure that this information

    accompanies the patient to all facilities while he/she is in custody Location

    Patients with diabetes should only be held where there is immediate access tohealth care professionals who are able to manage their care and respond todiabetes emergencies

    Access to diabetes medication and food Patients with diabetes must continue their medication without interruption and

    must alwayshave access to food. In addition, it is important to coordinate mealsand medication to maintain blood glucose levels in a safe range

    Sugar If a patient with diabetes requests a source of sugar, immediatelyprovide that

    person with a sugared soft drink, juice, or another fast-acting source of sugar,followed by bread or crackers

    Emergencies If a patient with diabetes requests medical care or exhibits symptoms of diabetic

    illness, immediatelyobtain assistance from a qualified health care professional.Know the fastest way to obtain medical help in the case of an emergency thatcannot be handled by on-site personnel

    d i

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    Summary and Key Points

    People with diabetes should receive care that meets nationalstandards. Being incarcerated does not change these standards.

    Patients must have access to medication and nutrition needed tomanage their diabetes.

    In patients who do not meet treatment targets, medical andbehavioral plans should be adjusted by health care professionals incollaboration with the custody staff.

    It is critical for correctional institutions to identify particularly high-risk patients in need of more intensive evaluation and therapy,including pregnant women, patients with advanced complications, ahistory of repeated severe hypoglycemia, or recurrent DKA.

    A comprehensive, multidisciplinary approach to the care of peoplewith diabetes can be an effective mechanism to improve overall

    health and delay or prevent the acute and chronic complications ofthis disease.

    R f

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    References

    Diabetes Management in Correctional Institutions. Agency forHealthcare Research and Quality. Available online athttp://guideline.gov

    Standards of medical care in diabetes. VI. Prevention andmanagement of diabetes complications. Agency forHealthcare Research and Quality. Available online at

    http://guideline.gov American Diabetes Association. Standards of medical care in

    diabetes 2011. Diabetes Care 2011;34(suppl 1):S11-12.Available online athttp://care.diabetesjournals.org/content/34/Supplement_1

    National Diabetes Fact Sheet, 2011. National Center forChronic Disease Prevention and Health Promotion. Division ofDiabetes Translation. Available online at http://www.cdc.gov

    C I f i

    http://guideline.gov/http://guideline.gov/http://care.diabetesjournals.org/content/34/Supplement_1http://www.cdc.gov/http://www.cdc.gov/http://care.diabetesjournals.org/content/34/Supplement_1http://guideline.gov/http://guideline.gov/
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    Contact Information

    Sr. Mary Jane Bookstaver:

    [email protected]

    mailto:[email protected]:[email protected]