a-1d diabetes an update on american diabetes association guidelines
TRANSCRIPT
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Diabetes: Updates on ADA Guidelines
January 2012
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Objectives
State the standards of diabetic care put forth by the
American Diabetes Association Discuss the co-morbidities of diabetes, the standards
of care that influence their management andstrategies to achieve the goals of care
Discuss ways correctional institutions can improve
compliance with the recommendations for diabetic
care in correctional institutions
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Diabetes Facts
Diabetes affects 25.8 million people in the United
States 18.8 million diagnosed
7 million undiagnosed
Diabetes is the leading cause of kidney failure, non-
traumatic lower limb amputations, and new cases ofblindness among adults in the United States
Diabetes is a major cause of heart disease and stroke
Diabetes is the seventh leading cause of death in theUnited States
Source: CDC Fact Sheet, 2011
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Diabetes Facts
Every 1% drop in A1c blood test results can decrease
the risk of microvascular complications of diabetesby 40%
Blood pressure control reduces the risk ofcardiovascular disease (heart disease or stroke)among people with diabetes by 33% to 50%, and the
risk of microvascular complications by 33%. In general, for every 10 mmHg reduction in systolic
blood pressure, the risk for any complications relatedto diabetes is reduced by 12%.
Reducing diastolic blood pressure from 90 mmHg to80 mmHg in people with diabetes reduces the risk ofmajor cardiovascular events by 50%.
Source: CDC Fact Sheet, 2011
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Diabetes Facts
Improved control of LDL cholesterol can reduce
cardiovascular complications by 20% to 50%. Detecting and treating diabetic eye disease can reduce
development of severe vision loss by an estimated 50%to 60%.
Comprehensive foot care programs risk assessment,
foot care education and preventive therapy, treatment offoot problems and referral to specialists can reduceamputation rates by 45% to 85%.
Detecting and treating early diabetic kidney disease bylowering blood pressure can reduce the decline in kidney
function by 30% to 70%. ACEIs and ARBs are moreeffective than other antihypertensive medications inreducing the decline in kidney function
Source: CDC Fact Sheet, 2011
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Magnitude of Complications
Diabetic
Retinopathy
Leading cause
of blindnessin working age
adults
Diabetic
Nephropathy
Leading cause ofend-stage renal disease
Stroke
Cardiovascular
Disease
2-fold to 4-foldincrease incardiovascularmortalityand stroke
Diabetic
Neuropathy
Leading cause of nontraumatic
lower extremity amputationsNational Diabetes Information Clearinghouse. At:http://www.niddk.nih.gov/health/diabetes/pubs/dmstats/dmstats.htm
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Guidelines 2011
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Diabetes Disease Management
Intake Medical Assessment
Complete medical historyand intake physical exam bylicensed health professionalin a timely manner
Insulin-dependent diabeticsshould have capillary bloodglucose (CBG) within 1 to 2hours of arrival
Medications and medical
nutrition therapy (MNT)continued withoutinterruption
Screening for Diabetes
Evaluate for diabetes risk
factors at intake physical and
as appropriate thereafter
BMI 25 with history of
hypertension or hyperlipidemia BMI 25 and additional risk
factors or age > 45 with or
without risk factors
If pregnant, risk assessment
for gestational diabetesmellitus (GDM) at first pre-
natal visit
Re-screen at 24-28 weeks
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Criteria for Testing for Diabetes
Adults who are overweight (BMI 25) and have additional riskfactors: Physical inactivity
First-degree relative with diabetes
High-risk race/ethnicity
Women who delivered a baby weighing > 9 lb or were diagnosed withGDM
Hypertension on therapy for hypertension HDL cholesterol < 35 mg/dl and/or triglyceride > 250 mg/dl
Women with polycystic ovarian syndrome (PCOS)
A1c > 5.7% on previous testing
History of cardiovascular disease
Other clinical conditions associated with insulin resistance If results are normal, repeat testing at three-year intervals or
more frequently depending on initial results and risk status
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Criteria for Diagnosis of Diabetes
A1c 6.5% - NEW!
OR
Fasting plasma glucose (FPG) 126 mg/dl (7.0
mmol/l) no caloric intake for at least 8 hours
OR Two-hour plasma glucose 200 mg/dl (11.1 mmol/l)
during an oral glucose tolerance test (OGTT)
OR
A random plasma glucose 200 mg/dl (11.1 mmol/l)
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Goals of Treatment - Glucose
A1c < 7.0%
Pre-prandial CBG 70 130 mg/dl Peak postprandial CBG < 180 mg/dl
Less stringent A1c goals may be appropriate for patients
with History of severe hypoglycemia, limited life expectancy,
advanced microvascular or macrovascular complications,extensive co-morbid conditions
Those with longstanding diabetes in whom general goal isdifficult to attain despite education, glucose monitoring andeffective doses of multiple glucose lowering agents includinginsulin
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Correlation of A1c with Estimated Average Glucose
Mean plasma glucose
A1C (%) mg/dl mmol/l
6 126 7.0
7 154 8.6
8 183 10.2
9 212 11.8
10 240 13.4
11 269 14.9
12 298 16.5
ADA. V. Diabetes Care. Diabetes Care 2011;34(suppl 1):S18. Table 9.
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Components of Management
Blood sugar control
Patient education Nutrition counseling
Medication
Physical activity
Foot care
Retinopathy
Nephropathy
Cardiac
Lipid Management
Smoking cessation
Vaccines
Transfer and discharge
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Blood Sugar Control
Goal is A1c < 7.0%
Chronic care clinic for management
Every 3 6 months if A1c consistently < 7.0%
Every 2 3 months if A1c is 7.0% - 9.0%
Every month if A1c > 9.0% until better control is achieved Achieving good control requires:
Patient education and motivation
Effective combination of medications
Appropriate diet and compliance
Daily blood glucose monitoring
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Patient Education
Nutrition including commissary choices
Medication
Empowerment for self-management
Choice
Control Consequences
Peer groups
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Nutritional Counseling
Individuals who have diabetes or pre-diabetes should
receive individualized medical nutrition therapy Include counseling regarding the better choices
from items available in the commissary
Use commissary purchase list as an additional
opportunity for education and counseling Encourage weight loss if BMI 25
Education regarding portion control
Think about implementing a heart healthy diet forALL inmates benefits everyone and reduces needfor special medical diets
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Medication
Formularies should provide access to usual and
customary oral medications and insulins to treatdiabetes and related conditions
Patients should have access to medications at dosing
frequencies that are consistent with their treatment
plan and direction
Correctional institutions and police lock-ups should
implement policies and procedures to diminish the
risk of hypo- and hyperglycemia during off-site travel
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Physical Activity
Exercise 150 minutes/week of moderate intensity
aerobic activity Almost everyone can walk
If there isnt sufficient place to walk on the grounds,consider setting aside gym time for walking around
the court or running laps Exercise does not mean everyone has to work out in
the weight room
In absence of contraindications, people with type 2diabetes should be encouraged to perform resistancetraining three times per week
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Foot care
Instruct the patient with diabetes to examine his/her
feet daily and report to medical at the first sign ofbreakdown
Examine the patients feet at every encounter
Annual comprehensive foot exam to includeinspection, assessment of pulses, testing for loss of
protective sensation (monofilament, pinprick, etc.)
Multidisciplinary approach at the first sign of foot
ulcer and for those with high-risk feet
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Monofilament Testing
Upper panel
To perform the 10-gmonofilament test, place thedevice perpendicular to theskin, with pressure applieduntil the monofilamentbuckles
Hold in place for 1 secondand then release
Lower panel
The monofilament testshould be performed at thehighlighted sites while thepatients eyes are closed
Boulton AJM, et al. Diabetes Care.2008;31:1679-1685
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Retinopathy
Initial dilated retinal and comprehensive eye exam by
an ophthalmologist or optometrist shortly afterdiagnosis
Subsequent examinations annually
High quality fundus photographs can detect most
clinically significant diabetic retinopathy.Interpretation should be performed by a trained eyecare provider. This is not a substitute for acomprehensive eye exam.
Eye exam in the first trimester with close follow upthroughout pregnancy and for one year postpartum
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Nephropathy
Annual test to assess urine albumin excretion in type 1
diabetic patients with diabetes duration of 5 years Annual test to assess urine albumin excretion in all type 2
diabetic patients starting at diagnosis
Serum Creatinine at least annually in all adults with
diabetes regardless of the degree of urine albuminexcretion
GFR at least annually to stage level of chronic kidneydisease
If micro- or macroalbuminuria, treat with ACE or ARB(contraindicated in pregnancy)
Reduction of protein intake if patient has CKD
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Stages of Chronic Kidney Disease
Stage Description
GFR (ml/min per
1.73 m
2
bodysurface area)
1 Kidney damage* with normal or
increased GFR
90
2 Kidney damage* with mildly decreased
GFR
6089
3 Moderately decreased GFR 3059
4 Severely decreased GFR 1529
5 Kidney failure
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Cardiovascular Disease
BP at every encounter goal is < 130/80
If not at goal: Lifestyle therapy for maximum of 3 months if systolic 130
139 or diastolic 80 89
Weight loss if overweight
Dietary Approaches to Stop Hypertension (DASH) diet
Increased physical activity
Moderation of alcohol intake
If systolic 140 or diastolic 90 at diagnosis or follow up,begin pharmacologic therapy in addition to lifestyle
therapyACE or ARB and diuretic (thiazide if GFR 30 andloop if GFR < 30)
Monitor kidney function and serum potassium levels
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Antiplatelet Agents
Consider aspirin therapy (75 to 162 mg/day) as a primaryprevention strategy in those with type 1 and type 2 diabetesat increased cardiovascular risk (10-yr risk > 10%)
Includes men > 50 years or women > 60 years with at least oneadditional major risk factor (family history of CVD, HTN, smoking,dyslipidemia, albuminuria)
ASA not recommended for those at low cardiovascular risk
Use aspirin as a secondaryprevention strategy in patientswith diabetes and history of CVD
For patients with CVD and documented ASA allergy,clopidogrel (75 mg/day) should be used
Combination therapy with ASA and clopidogrel is reasonablefor up to one year after an acute coronary syndrome
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Lipid Management
Fasting lipid profile at least annually
Goal is LDL-C < 100 mg/dl
Goal for those with CVD is < 70 mg/dl
If goal is not met on maximum drug therapy, reduction of30% - 40% from baseline is an alternative goal
Lifestyle therapy for all diabetic patients Statin therapy should be added to lifestyle therapy,
regardless of lipid levels, for diabetic patients:
With overt CVD
Without CVD who are over the age of 40 and have one or moreother CVD risk factor
Statin therapy is contraindicated in pregnancy
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Smoking Cessation
Advise all patients not to smoke
Include smoking cessation counseling and otherforms of treatment as a routine component of
diabetes care
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Immunizations
Provide an influenza vaccine annually to all diabetic
patients 6 months of age Administer pneumococcal polysaccharide vaccine to
all diabetic patients 2 years
One-time revaccination recommended for those > 64
years previously immunized at < 65 years ifadministered 5 years ago
Other indications for repeat vaccination:
Nephrotic syndrome
Chronic renal disease
Immunocompromised states
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Transfer and Discharge
For all inter-institutional transfers, complete a
medical transfer summary to be transferred with thepatient
Diabetes supplies and medication should accompany
the patient during transfer
Begin discharge planning with adequate lead time to
ensure continuity of care and facilitate entry into
community diabetes care
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Diabetic Emergencies
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Diabetes Emergencies
People experiencing diabetes emergencies may:
Appear intoxicated
Appear under the influence of drugs
Appear uncooperative
When in doubt, ask the person or his/her
companions if the person has diabetes and check for
medical identification bracelet, necklace, or card
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Warning Signs that Require Action
Hypoglycemia
Sweating
Shakiness
Anxiety
Confusion
Difficulty speaking Uncooperative behavior
Paleness
Irritability
Dizziness
Inability to swallow
Seizure
Loss of consciousness
Hyperglycemia
Flushed skin
Labored breathing
Confusion
Cramps Very weak
Sweet breath
Nausea
Loss of consciousness
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Emergency Treatment
Hypoglycemia
Give can sugared (non-
diet) soda unless the
person cannot swallow
Obtain immediate
assistance from a qualifiedhealth care professional
Continue to give sugar
source every 15 minutes
until blood sugar > 70
If unconscious, give
Glucagon or D50 IV
Hyperglycemia
Give access to water
Give access to bathroom
Give access to medication
Obtain immediateassistance from a qualified
health care professional
Give regular NOT LONG-
ACTINGinsulin
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How to Ensure Safety of Patients with Diabetes
Identification Promptly identify patients with diabetes and ensure that this information
accompanies the patient to all facilities while he/she is in custody Location
Patients with diabetes should only be held where there is immediate access tohealth care professionals who are able to manage their care and respond todiabetes emergencies
Access to diabetes medication and food Patients with diabetes must continue their medication without interruption and
must alwayshave access to food. In addition, it is important to coordinate mealsand medication to maintain blood glucose levels in a safe range
Sugar If a patient with diabetes requests a source of sugar, immediatelyprovide that
person with a sugared soft drink, juice, or another fast-acting source of sugar,followed by bread or crackers
Emergencies If a patient with diabetes requests medical care or exhibits symptoms of diabetic
illness, immediatelyobtain assistance from a qualified health care professional.Know the fastest way to obtain medical help in the case of an emergency thatcannot be handled by on-site personnel
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Summary and Key Points
People with diabetes should receive care that meets nationalstandards. Being incarcerated does not change these standards.
Patients must have access to medication and nutrition needed tomanage their diabetes.
In patients who do not meet treatment targets, medical andbehavioral plans should be adjusted by health care professionals incollaboration with the custody staff.
It is critical for correctional institutions to identify particularly high-risk patients in need of more intensive evaluation and therapy,including pregnant women, patients with advanced complications, ahistory of repeated severe hypoglycemia, or recurrent DKA.
A comprehensive, multidisciplinary approach to the care of peoplewith diabetes can be an effective mechanism to improve overall
health and delay or prevent the acute and chronic complications ofthis disease.
R f
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References
Diabetes Management in Correctional Institutions. Agency forHealthcare Research and Quality. Available online athttp://guideline.gov
Standards of medical care in diabetes. VI. Prevention andmanagement of diabetes complications. Agency forHealthcare Research and Quality. Available online at
http://guideline.gov American Diabetes Association. Standards of medical care in
diabetes 2011. Diabetes Care 2011;34(suppl 1):S11-12.Available online athttp://care.diabetesjournals.org/content/34/Supplement_1
National Diabetes Fact Sheet, 2011. National Center forChronic Disease Prevention and Health Promotion. Division ofDiabetes Translation. Available online at http://www.cdc.gov
C I f i
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Contact Information
Sr. Mary Jane Bookstaver:
mailto:[email protected]:[email protected]