FoodMicroSystems A Roadmap Towards Applications in the Food Industry Workshop – Madrid (Spain), 29 November 2013 Christophe Cotillon Deputy Manager ACTIA

16, rue Claude Bernard, 75005 Paris, France Phone: +33 1 44088615, E-mail: c.cotillon@actia-asso.eu www.actia-asso.eu FoodMicroSystems has been supported by the European Union’s Seventh Framework Programme ([FP7/2007-2013] under grant agreement n°287634

FoodMicroSystems

European Commission funded Support Action

(798 K€ EC contribution)

2 years from September 2011

Coordination: ACTIA (France)

9 partners

Objective: initiate the implementation of

microsystems in food and drink sector

Main results: 4 roadmaps

Project ID

3

4

The consortium

Challenge Unite two remote areas

Food

Micro systems

How? Promote cooperation between the two communities

Overview

5

13 meetings

3 technological roadmaps

+ 1 application roadmap

5 Reports Needs of food industry

Potential of microsystems + consumer perception +

ethics + regulation

Website

6

Approach

Microsystems (MST): From a

chip… to an instrument

device

Miniaturised and cost-effective instruments

Component or subsystem

wafer

portable benchtop

on-line

Food industry needs and demands

• Food safety (fast, portable, cheap and easy-to-

use devices)

• Food quality (continuous and simultaneous

measurements of several parameters)

• Food sustainability (water and energy

consumption, cleaning operations…)

• Authentification, traceability, detection of

frauds, adulteration…)

• Intelligent packaging

8

Foodchain monitoring and traceability: safety and quality assessment stages

Consumption Recollection Transport Transport Storage

Storage

Processing

Farmers Industrials Retailers Consumers

(transforming, poisoning)

(active-evolving, degrading)

(degrading)

(multi-sensing, multipoint sensing, continuous monitoring, automation/non-specialist intervention)

MST contribution: closeness to the foodstuff & power of analysis & speed

Safety and Quality Assessment with MST

to eat, or not to eat.

Where can MST be used?

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Synthesis table of technological needs for Microsystems development in the different activity of the dairy sector:

Dairy sector activities

Milk collection, transport,

storage

Treatment of milk

Transformation Conditioning

Thematics or

Technologies

Process optimization Ability indicator of milk to the growth of lactic acid bacteria

Process optimization Ability indicator of milk to the clotting Control online of pH kinetic (acidification during cheesemaking, deacidification during ripening) Control online of the drainage in curd and cheeses Control online of clotting properties (firmness, rate of firming) Control of the maturity of cheeses during the ripening Control of the opening characteristics (hard cheeses)

Intelligent packaging Leak indicator (ripening under film, vacuum packaging) Cold logistics: Time/Temperature indicator

Analyzing Online indicative measurement of microbiological quality of products (Pathogens, Total Flora, Bacteriophage)

Measure/evaluation of the lipolysis in milk

Control of residual antibiotics on the farm

Measure of whey proteins denatured

Measure/evaluation of the fermentation activities (lactates, volatile fatty acids) Measure/evaluation of the mineralization (soluble and colloidal calcium) Measure of the rate of salt and its distribution Measure/evaluation of the proteolysis in cheese

Cleaning Online indicative measurement of cleaning and/or disinfection efficiency Online indicative measurement of the presence of biofilms

Traceability

Miniaturized systems for products tracking along the production lines (Ex : RFID chips)

Miniaturized systems for tracking the thermal history of milk

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Microsystem Techn. Application Meat Fish Dairy Fruit & Vegetables Beverages

Biosensors

Volatile detection/quantification to monitor quality deterioration, e.g. in the headspace of the packaged product

Real time determination of use-by-date of packaged

products

Real time determination of use-by-date of packaged

products

Process control in dairy industry and real time

determination of use-by-date

Monitoring of storage conditions and real time

determination of use-by-date of packaged products

Process monitoring

Micro-organism detection/quantification

Food safety, usually off-line or near-line determination of pathogens and/or spoilage organisms

Food safety assurance and shelf life determination in combination with spoilage

models

Food safety assurance and shelf life determination in combination with spoilage

models

Spoilage detection

Food safety assurance and shelf life determination in combination with spoilage

models

Food safety, spoilage detection and process

monitoring (fermentation)

Chemical contaminant detection/quantification

Food safety and regulatory compliance, usually off-line lab-on-a-chip in combination with sampling

Detection of antibiotics, dioxins, etc.

Detection of antibiotics (aquaculture) and

environmental residues

Detection of residues and environmental substances

Detection of residues and bacterio- and mycotoxins

Processing technology

Filtration, fractionation, emulsification using MST devices that combine uniformity with high accuracy

Pasteurisation by filtration; fractionation of milk into constituents; high quality

and/or multiple emulsions

Removal of yeast or bacteria

Microfluidics

Micro-channel emulsification; inkjet emulsification/particlre production; production of fine chemicals

emulsification; ingredient

production Ingredient production

Tracking and tracing

Communication of product specific information to logistic systems in the chain and/or retail (cassier) or consumer systems (refrigerator, microwave)

Chain management; primary production management;

origine determination; authentication;

communication of sensor data

Chain management; time/temperature

monitoring

Time/temperature monitoring

Chain management

Authentication; in combination with sensors:

primary production management

Aroma/Gas sensors and sensing systems

Volatile detection/quantification to monitor quality deterioration, e.g. in the headspace of the packaged product

Indirect pathogen detection via volatile by-products;

meat quality discrimination according to escatol and

androsterona odours

Fish freshness monitoring by volatiles; differentiation between fresh fish and

frozen/thawed fish

i.e. Fruit Rippenes

monitoring by ethilene vapours detection

identification of raw materials, for quality and

antifraud in fruit juices, oils,..

pH sensors and sensing systems

pH and other ion detection as potential contaminants in food; pH sensors as part of e-tongues for quality assurance

pH detection in pork meat for quality determination

Process control of dairy

product factories

Identification and quality control of beverages;

antifraud,…

Roadmapping methodology

NEXUS Methodology

technology 1

technology x

2000 20102005

Product/Component trendsProduct/Component trends

Fu

nc

tio

na

lity

/perf

orm

an

ce

device

1

device

2

device

x

....

device 1

device x

2000 20102005

Functional trendsFunctional trends

Fu

nc

tio

na

lity

/cu

sto

me

r b

en

efi

t

func.

1

func.

2

func.

x

....

Dairy industry: from drivers to technologies needed

Time

Dairy technology priorities

Drivers

Industry priorities

Capabilities needed

Devices needed

Higher priority Lower priority

Better emulsions

HealthAuthenticityQualityCost

Proven provenance

Reduction of waste

Efficient usage of resources

Control of purity

Detection of unwanted

content

Condition based

maintenance

Cold filtration

Profiling & ripeness

Better emulsification technologies

Pathogen detection

Other detection

Fouling detection

Other testing

New processing

technologies

Protein detection?

Dairy Roadmap for the detection of chemical

contamination, residues and other Detection of chemical contamination,

residues and other

Processing contaminants:

chemicals or metal parts / chips from the

equipment used

Processing contaminants:

chemicals or metal parts / chips from the

equipment used

Melamine Melamine

Metal detector

Lateral flowsensor

Lateral flowsensor

Antibiotics Antibiotics

Quantitative assays

Allergens Allergens

Mobile chromato-graphic systems

Pesticides / HerbicidesPesticides / Herbicides Microfluidic

lab-on-chip sensor

Multi-AnalyteMulti-

Analyte

Lateral flowsensor Lactose Lactose

Microfluidic lab-on-chip sensor

Time

3 5 10 years

Fu

nc

tio

na

lity

/ c

us

tom

er

be

ne

fit

Devices/functions needed for cheese quality control Quality control for cheese

Time

3 5 10 years

Fu

nc

tio

na

lity

/ c

us

tom

er

be

ne

fit

Profiling (origin)Profiling (origin)

ColourColour

Holes / openingsHoles /

openings

Tenderness / firmness

Tenderness / firmness

Ripeness / bacteria activity

Ripeness / bacteria activity

TextureTexture

Temperature / humidityTemperature / humidity

Taste qualityTaste

quality

Aromatic quality

Aromatic quality

Moisture and salt contentMoisture and salt contentDielectric sensors

Tactile sensors

Physical

Sensors for ions and organic molecules

Biosensors

Gas sensors

Physical sensors

GC/MS

Integrate in package label

Imaging

Mid infrared spectroscopy

Ultrasound

SpectrometricImaging

Chemical sensors

Technological trends for gas sensors Gas Sensors

Level of

Inte

gra

tion/F

unctio

nalit

y

Time(years)

3 5 10

MOX SensorsNew sensitive materials

NanoWires, CNTs…for higher LOD: ppb

Integration of low cost microhotplates on standard

CMOS- SOI, < 10 mW

New polymer substrates + low temp. materials for

ultra low power systems

Nanomaterials as post-processing at wafer level

MOX SensorsArrays

Ultra Low Power

MOX SensorArrays

NDIR Optical Systems

New materials for more performant IR detectors

Integrable low cost CMOS compatible IR emitters

(< 1W)

System Integration. Passive Filters, Fabry-Perot.

Development of More efficient absorption cells

Integration with analogelectronics, FPGAs,…

Technological trends for e-noses E-nose

Time (years)

3 5 10

Simple e-nose for portability

Integration of optimised sensor arrays

Better types of gas sensors:MOX, SAW, cantilever, optical,…

Development of new olfactory models based on human

perception

Improvement of electronics control systems

Better Data Processing algorithms

Level of

Inte

gra

tion/F

unctio

nalit

y

Complete Sensing systems

Combination with complementary systems

(GC…)

Technological trends for bio-chemical sensors Bio-Chemical Sensors

Level of

Inte

gra

tion/F

unctio

nalit

y

Time(years)

3 5 10

New chemical membranes for higher sensitivity and fast

response

FIA systems for making calibration easy

Miniaturisation of chemical transducers, for portability

Chemical Sensors

Multiparametric systems

BioSensors

Non-silicon substratesfor low cost

Better surface immobilisation techniques, membranes,

magnetic beads, for multiple use

Novel microfluidics, sample processing, for

avoiding culturing.FIA systems

Multi sensing integration

New nano and biomaterials for improving selectivity and

reducing interferences

Microorganism detection using

the example of µPCR

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Trend from lab to in-line measurement:

Example of pathogene detection

Industry constraints

• Robustness of devices

• Reliability of measurements

• Compatibility with food processes

• Time to process information and provide results

• Cost per measurement

• Sampling strategy (number of measures, when,

where, (pre)treatment of samples…)

• Cleanability

• Compatibility with current regulations for food 22

Consumer perception and ethical issues

• Limited trust towards the food chain

• Control of the technology

• Use to track consumers after purchase (privacy violation)

• Health concerns (chemical contamination, foreign

particles…)

• Incidence on the price of food product

• Effects on environment (bio-accumulation of particles,

packaging…)

• Transparancy about application and clear regulatory

frame

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Overall conclusions from the Microsystems for

Food Roadmapping

=> the food sector is a significant market to MST

developers

– MST can help the food sector to address its key

challenges (safety, quality, authenticity and optimise

the use of resources)

– There are strong needs for new solutions (FMS has

many examples in its reports)

=> FMS provides ideas for H2020 (Innovation projects)

– Roadmaps on 3 sectors can be used as source of

inspiration by the EC in H2020

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MNT for Food – The way forward…

• Opportunities for MNT: – Technologies to increase shelflife & improve taste / nutritional value

– Even new food products are possible (e.g. through emulsification)

– Bring Lab analytics to the manufacturing line

– Re-use results from other sectors (medical) research

• How to move forward: – Funding: national, EC - coordinate ICT and food funding?

– Networking / communication along the “MNT - Food industry”

– Continue FoodMicroSystems roadmapping process

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Thank you for your attention!

Preliminary FoodMicroSystems roadmaps have been published at: http://www.foodmicrosystems.eu/?page_id=1159 FoodMicroSystems: EC-funded Coordination Action to provide a Roadmap of the "Microsystems for Food" Sector www.foodmicrosystems.eu

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