2 3...on implant surfaces: a review of current knowledge and opinions. wennerberg a, albrektsson t....

2 3

The future is now

I m p l a n t S y s t e mw w w. s i n p l a n t . c o m

HAnano ® Surface

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SimplicityInnovationNanotechnology

2 3

HAnano® SURFACEThe goal of continuous search for implant surfaces

improvement is to boost scar response quality and hasten bone response, creating the possibility of an aesthetic and functional rehabilitation in short time compared to what is conventionally proposed25. Hydroxyapatite (HA), which is the main mineral present in the natural bone structure, when applied on the surface of nanostructured titanium implants, forms a homogeneous and stable coating func-tioning as a scar catalyst that speeds up Osseointegration when compared to conventional surfaces. This coating dif-fers significantly in thickness, application method, clinical predictability and scientific support when compared to the HA surfaces used in the past*.

From 2005 on, HAnano® surfaces have been develo-ped by researchers from leading universities in Gothenburg (Sweden). Scientists from several countries have tested and approved its effectiveness, the results of which have been published in dozens of articles in world-renowned scientific journals1;3;4. The HAnano® coating is formed by hydroxyapatite nanocrystals, with size and shape similar to those of human bone, sintered on a microrough titanium measuring 20 nm thick that promotes a change on surface energy, increasing the hydrophilicity and providing substrate that stimulates a greater osteoblasts multiplication25;†. These crystals are applied to the titanium implant surface after a chemical tre-atment with double thermal acid attack (DAA), which brin-gs a series of benefits to the Unitite implants, such as the healing process acceleration, high hydrophilicity, increased bone formation (BIC - Bone Implant Contact ) and the quality improvement of the new bone formed (BAFO - Bone Area Fraction Occupancy), keeping the original implant microto-pography 24;27.

The HAnano® present on the surface of the Unitite im-plant has shown an improvement in scar response in mole-cular tests of signal transduction, where the proteins invol-ved in the scar process recorded a substantial increase in concentration, presenting the coating positive effect on the interaction with the pre-osteoblastic cells36. Likewise, there was an increase in the concentration of important osteoge-nic markers, such as alkaline phosphatase and ostecalcin, in a clear signaling of the mineralization process acceleration §.

Among the most relevant aspects, with the greatest clinical significance, is the bone mechanical quality which is

The positive effects of HAnano's surface have been evaluated and proven in numerous scientific publications, some

examples of publications are:

SCIENTIFIC PUBLICATIONS

formed around this highly hydrophilic Unitite surface, which derives from the resulting ionic potential of the HAnano®.

It has been shown that the bone mechanical pro-perties, such as modulus of elasticity and hardness in the fraction of bone area formed (BAFO), increased significantly HAnano® 16;14;27, not only in the vicinity of the bone implant interface (BIC), but also within the healing chambers and es-pecially in distant areas of the implants. According to a in vivo study, published by Coelho and collaborators, there was an increase of +% BIC and +% BAFO - indexes superior to traditional surfaces implants¶ .

A comparative study published by Wennerberg A. **, assessing different types of surfaces in animals, has shown that HAnano® greatly improves the quality of the bone formed and accelerates the healing process. Following the same line of research, Cavalcanti and colleagues compared grade IV titanium implants without surface treatment, with a double acid attack and with HAnano® coating; and the result demons-trated complete mineralization of the latter in 28 days45. Other clinical studies recently published by Pessoa and col-leagues, evaluating systemically healthy patients with no local bone involvement, point to the same result in humans, emphasizing the need to associate an ideal macrogeometry, microgeometry and nanometric surface to achieve satisfac-tory results in time as in the case of the Unitite implant29.

The resulting ionic potential of the HAnano® coating as-sociated with its microtopography generate an increase in the titanium surface energy, making the implant highly hydrophi-lic, which guarantees the presence of blood and its compo-nents in the healing chamber, in additon to generating greater adsorption of the proteins involved in the Osseointegration process, demonstrating its bioactive potential.

Unlike technologies used in past decades, the HAnano® surface coating has a nanometric thickness that does not alter its surface roughness, is reabsorbable and functions as a scar catalyst so that the bone tissue can in-teract directly with the titanium in shorter periods of time. The use of a patented and proven method of coating appli-cation ensures its stability and surface homogeneity †, which is paramount to ensure its use in several types of bone densi-ty and to guarantee the success of rehabilitation treatment with high levels of predictability.

"NANO HYDROXYAPATITE STRUCTURES INFLUENCE EARLY BONE FORMATION."

"THE EFFECT OF CHEMICAL AND NANOTOPOGRAPHICAL MODIFICATIONS ON THE EARLY STAGES OF OSSEOINTEGRATION."

Meirelles L, Arvidsson A, Andersson M, Kjellin P, Albrektsson T, Wennerberg A.

Journal of Biomedical Materials Research Part A Volume 87A, Issue 2,2008, pp. 299-307

Meirelles L, Currie F, Jacobsson M, Albrektsson T, Wennerberg A.

The International Journal of Oral and Maxillofacial Implants Volume 23, Issue 4, 2008, pp. 641-647

*. HA particles can be released from well-fixed HA-coated stems: histopathology of biopsies from 20 hips 2-8 years after implantation. Røkkum M, Reigstad A, Johansson CB. Acta Orthop Scand 73 (3), 298-306. 6 2002

†. On implant surfaces: a review of current knowledge and opinions. Wennerberg A, Albrektsson T. Int J Oral Maxillofac Implants. 2010 Jan-Feb;25(1):63-74.

§. Different patterns of bone fixation with hydroxyapatite and resorbable CaP coatings in the rabbit tibia at 6, 12, and 52 weeks. Reigstad O, Johansson C, Stenport V, Wennerberg A, Reigstad A, Røkkum M. J Biomed Mater Res B Appl Biomater. 2011 Oct;99(1):14-20.

¶. Biomechanical and bone histomorphologic evaluation of four surfaces on plateau root form implants: an experimental study in dogs. Coelho PG, Granato R, Marin C, Bonfante EA, Janal MN, Suzuki M. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 May;109(5):e39-45.

**. A histomorphometric and removal torque study of screw-shaped titanium implants with three different surface topographies. Wennerberg A, Albrektsson T, Andersson B, Krol JJ. Clin Oral Implants Res. 1995 Mar;6(1):24-30.

4 5

UNITITE PRIMEDiameter (mm)

8.5

10.0

11.5

13.0

15.0

Length (mm)

3.5

4.3

5.0

UNITITE SLIMDiameter (mm)

10.0

11.5

13.0

Length (mm)

2.9

UNITITE COMPACTDiameter (mm)

4.0

5.0

6.0

Length (mm)

5.0

6.0

7.0

PRIME, SLIM and COMPACT: three implant lines, which meet the most

diverse needs.

High hydrophilicity: HAnano® surface combined with implant

macrogeometry expands surface energy and accelerates the

Osseointegration process.

Healing chambers: while the larger coils touch the bone, guaranteeing

primary stability, the smaller coils create a chamber that increases the

contact between the clot and the implant, favoring the speed and quality

of the healing process.

Hybrid Macrogeometry: at first, the implant presents a cylindrical shaped

body and becomes progressively conical, suitable for all bone densities.

4 5

6 7

SURGICAL

BONE EXPANDER

The same kit fits the entire Unitite line.

SAFE DRILL

ROTARY EXPANDER

SHORT DRILLOSTEOTHES

PROSTHETIC

BONE GRAFTSINUS LIFT

OUR KITS

Color coded to simplify clinical use.

Small number of drills

needed for osteotomy.

Torque wrench with torque gauge.

DLC* coated drills: increased durability and cutting power.

Duo-digital key included

* Diamond like carbon

8 9

CODE DIAM. LENGTH

3.5 8.5

3.5 10.0

3.5 11.5

3.5 13.0

3.5 15.0

4.3 8.5

4.3 10.0

4.3 11.5

4.3 13.0

4.3 15.0

5.0 8.5

5.0 10.0

5.0 11.5

5.0 13.0

5.0 15.0

CODE DIAM. LENGTH

CODE

CODE

CIMU 3308 3.3 0.8

CIMU 3315 3.3 1.5

CIMU 3325 3.3 2.5

CIMU 3335 3.3 3.5

CIMU 3345 3.3 4.5

CIMU 3355 3.3 5.5

CIMU 4508 4.5 0.8

CIMU 4515 4.5 1.5

CIMU 4525 4.5 2.5

CIMU 4535 4.5 3.5

CIMU 4545 4.5 4.5

CIMU 4555 4.5 5.5

TMFMU

ANMU

CODE DIAM.

CODE

CPTMU 3501-H

CPTMU 3502-H

CPTMU 3503-H

CPTMU 3504-H

CPTMU 4501-H

CPTMU 4502-H

CPTMU 4503-H

CPTMU 4504-H

CODE DIAM. LENGTH EUCLAMU 3501-H 3.8 1.0

EUCLAMU 3502-H 3.8 2.0

EUCLAMU 3503-H 3.8 3.0

EUCLAMU 3504-H 3.8 4.0

EUCLAMU 4501-H 4.5 1.0

EUCLAMU 4502-H 4.5 2.0

EUCLAMU 4503-H 4.5 3.0

EUCLAMU 4504-H 4.5 4.0

LENGTH 1.0

2.0

3.0

4.0

1.0

2.0

3.0

4.0

1.8PTM 181.8PTM 1816

For temporary cylinder

Immediate loading: Recommend torque above 45 N.cm.

Early loading (as from 28 days)**: Recommended torque from 30 to 45 N.cm.

Late loading: Torque less than 30 N.cm.

* In bone types I and II the bone tap is required to not exceed the recommended torque, and ensure the correct healing process. ** Contraindicated for patients with diabetes, smokers, pos extraction alveolus, active periodontaldisease and osteoporosis. Also in patients during radiotherapy and chemotherapy.

Analog

Closed tray transfer

Healing capTemporary

titanium cylinder Plastic/Co-Cr UCLA Retaining screw

Includes cover screw of 2.0 mm.

Recommended from 1.5 mm to 2.0 mm

For installation at bone level it is necessary to use cover screw TIMU 0012.

Indicated for all type of bones.

Internal angle of 11.5°.

All measurements in mm

UCM 3585N

UCM 3510N

UCM 3511N

UCM 3513N

UCM 3515N

UCM 4385N

UCM 4310N

UCM 4311N

UCM 4313N

UCM 4315N

UCM 5085N

UCM 5010N

UCM 5011N

UCM 5013N

UCM 5015N

Maximum Torque: 60 N.cm.

Speed of the initial drills: 1,200 rpm.

Speed of the drills 2.7 to 5.0mm: 800 rpm.

Speed of the bone tap: 20 rpm*.

Insertion speed: 20 to 40 rpm.

CODE

TMAMU

Open traytransfer

20 N.cm 20 N.cm 20 N.cm

Hex Screw

Anti-Rotational Component

Squared Screw

Abutment Screw

Rotational Component

DIAM.

3.5

3.5

3.5

3.5

4.5

4.5

4.5

4.5

For UCLA

PRIM

E

* Coming soon. Check availability with your distributer.

UNITITE PRIMERESTORATIVE OPTIONSTEMPORARY/CEMENTED/SCREW RETAINED

10 11

DIAM. DIAM. CODECODE LENGTH

CODE DIAM. LENGTH

CPSIT 3340 3.3 4.0

CPSIT 3360 3.3 6.0

CPSIT 4540 4.5 4.0

CPSIT 4560 4.5 6.0

CODE DIAM. LENGTH

3.3 4.0

3.3 6.0

4.5 4.0

4.5 6.0

CODE DIAM. LENGTH

3.5 8.5

3.5 10.0

3.5 11.5

3.5 13.0

3.5 15.0

4.3 8.5

4.3 10.0

4.3 11.5

4.3 13.0

4.3 15.0

5.0 8.5

5.0 10.0

5.0 11.5

5.0 13.0

5.0 15.0

DIAM. LENGTH

3.3 0.8

3.3 1.5

3.3 2.5

3.3 3.5

3.3 4.5

3.3 5.5

4.5 0.8

4.5 1.5

4.5 2.5

4.5 3.5

4.5 4.5

4.5 5.5

CODE DIAM. TRANSMUCOSAL LENGTH

CEMENTATION LENGTH

3.3 0.8 4.0

3.3 1.5 4.0

3.3 2.5 4.0

3.3 3.5 4.0

3.3 4.5 4.0

3.3 5.5 4.0

3.3 0.8 6.0

3.3 1.5 6.0

3.3 2.5 6.0

3.3 3.5 6.0

3.3 4.5 6.0

3.3 5.5 6.0

4.5 0.8 4.0

4.5 1.5 4.0

4.5 2.5 4.0

4.5 3.5 4.0

4.5 4.5 4.0

4.5 5.5 4.0

4.5 0.8 6.0

4.5 1.5 6.0

4.5 2.5 6.0

4.5 3.5 6.0

4.5 4.5 6.0

4.5 5.5 6.0

CODE DIAM. HIGHER TRANSMUCOSALLENGTH

LOWERTRANSMUCOSAL LENGTH

CEMENTATION LENGTH

3.3 2.6 1.5 4.0 17°

3.3 3.6 2.5 4.0 17°

3.3 4.6 3.5 4.0 17°

3.3 3.15 1.5 4.0 30°

3.3 4.15 2.5 4.0 30°

3.3 5.15 3.5 4.0 30°

3.3 2.6 1.5 6.0 17°

3.3 3.6 2.5 6.0 17°

3.3 4.6 3.5 6.0 17°

3.3 3.15 1.5 6.0 30°

3.3 4.15 2.5 6.0 30°

3.3 5.15 3.5 6.0 30°

4.5 3.0 1.5 4.0 17°

4.5 4.0 2.5 4.0 17°

4.5 5.0 3.5 4.0 17°

4.5 3.75 1.5 4.0 30°

4.5 4.75 2.5 4.0 30°

4.5 5.75 3.5 4.0 30°

4.5 3.0 1.5 6.0 17°

4.5 4.0 2.5 6.0 17°

4.5 5.0 3.5 6.0 17°

4.5 3.75 1.5 6.0 30°

4.5 4.75 2.5 6.0 30°

4.5 5.75 3.5 6.0 30°

UCM 3585N

UCM 3510N

UCM 3511N

UCM 3513N

UCM 3515N

UCM 4385N

UCM 4310N

UCM 4311N

UCM 4313N

UCM 4315N

UCM 5085N

UCM 5010N

UCM 5011N

UCM 5013N

UCM 5015N

CODE

CIMU 3308

CIMU 3315

CIMU 3325

CIMU 3335

CIMU 3345

CIMU 3355

CIMU 4508

CIMU 4515

CIMU 4525

CIMU 4535

CIMU 4545

CIMU 4555


Healing cap Analog

One-Piece StraightUniversal Abutment

AISIT 334008

AISIT 334015

AISIT 334025

AISIT 334035

AISIT 334045

AISIT 334055

AISIT 336008

AISIT 336015

AISIT 336025

AISIT 336035

AISIT 336045

AISIT 336055

AISIT 454008

AISIT 454015

AISIT 454025

AISIT 454035

AISIT 454045

AISIT 454055

AISIT 456008

AISIT 456015

AISIT 456025

AISIT 456035

AISIT 456045

AISIT 456055

Angled universal abutment*

PolyacetalImpression Transfer

APASIT 341715

APASIT 341725

APASIT 341735

APASIT 343015

APASIT 343025

APASIT 343035

APASIT 361715

APASIT 361725

APASIT 361735

APASIT 363015

APASIT 363025

APASIT 363035

APASIT 441715

APASIT 441725

APASIT 441735

APASIT 443015

APASIT 443025

APASIT 443035

APASIT 461715

APASIT 461725

APASIT 461735

APASIT 463015

APASIT 463025

APASIT 463035

TSIT 3340 3.3

TSIT 3360 3.3

TSIT 4540 4.5

TSIT4560 4.5

3.3 4.0

3.3 6.0

4.5 4.0

4.5 6.0

LENGTH

4.0

6.0

4.0

6.0

ASIT 3340

ASIT 3360

ASIT 4540

ASIT 4560

ANG.

Temporary acrylic cylinder

Calcinable polyacetal cylinder

CCSIT 3340

CCSIT 3360

CCSIT 4540

CCSIT 4560

CODE

**Two-Pieces StraightUniversal Abutment

APSIT 334008

APSIT 334015

APSIT 334025

APSIT 334035

APSIT 334045

APSIT 334055

APSIT 336008

APSIT 336015

APSIT 336025

APSIT 336035

APSIT 336045

APSIT 336055

APSIT 454008

APSIT 454015

APSIT 454025

APSIT 454035

APSIT 454045

APSIT 454055

APSIT 456008

APSIT 456015

APSIT 456025

APSIT 456035

APSIT 456045

APSIT 456055

10 N.cm

PRIM

E

* Use hexagonal driver 0.9 mm

** Coming soon. Check availability with your distributer.

10 N.cm20 N.cm

Hex Screw


Squared Screw

Abutment Screw


UNITITE PRIMEUNIVERSAL ABUTMENT - PRE-MADE POSTSCEMENTED RETAINED RESTORATIONS

12 13


CODE DIAM LENGTH

3.5 8.5

3.5 10.0

3.5 11.5

3.5 13.0

3.5 15.0

4.3 8.5

4.3 10.0

4.3 11.5

4.3 13.0

4.3 15.0

5.0 8.5

5.0 10.0

5.0 11.5

5.0 13.0

5.0 15.0

CODE

CODE

CODE

PRH 30

LENGTH

3.0

CODE

ANAC

CODE

TMFA 4800

TMFA 4806

Healing cap

UCM 3585N

UCM 3510N

UCM 3511N

UCM 3513N

UCM 3515N

UCM 4385N

UCM 4310N

UCM 4311N

UCM 4313N

UCM 4315N

UCM 5085N

UCM 5010N

UCM 5011N

UCM 5013N

UCM 5015N

CODE DIAM LENGTH

3.3 0.8

3.3 1.5

3.3 2.5

3.3 3.5

3.3 4.5

3.3 5.5

4.5 0.8

4.5 1.5

4.5 2.5

4.5 3.5

4.5 4.5

4.5 5.5

CIMU 3308

CIMU 3315

CIMU 3325

CIMU 3335

CIMU 3345

CIMU 3355

CIMU 4508

CIMU 4515

CIMU 4525

CIMU 4535

CIMU 4545

CIMU 4555

Conical abutment AnalogConical abutment protector

Retainingscrew

Polishing protector

Open tray transfer

Temporarytitanium cylinder


Calcinable Co-Cr cylinder

CODE DIAM LENGTH

4.8 0.8

4.8 1.5

4.8 2.5

4.8 3.5

4.8 4.5

4.8 5.5

CODE

PPAC 01

ACMU 4808

ACMU 4815

ACMU 4825

ACMU 4835

ACMU 4845

ACMU 4855

PA 4855

Laboratoryscrew

CODE

TMAA 4800

TMAA 4806 CODE

CODE

CPAC 06-3

CPAC 00-3

CALE 06-3 Cobalt-chrome

CALE 00-3 Cobalt-chrome

PL 1405 Short

PTMA 13-1 Long

20 N.cm

10 N.cm

10 N.cm

10 N.cm

PTA 4800-3

PTA 4806-3

PRIM

E

Hex Screw


Squared Screw

Abutment Screw


UNITITE PRIMECONICAL ABUTMENTSINGLE/MULTIPLE SCREW RETAINED RESTORATIONS

14 15

PRIM

E

Retainingscrew

Retainingscrew

PRH 20 2.0

CODE LENGTH

PRH 30 3.0

Laboratoryscrew

Laboratoryscrew

PL 1405 short

CODE

PTMA 13-1 long

10 N.cm

CODE DIAM. LENGTH

3.3 0.8

3.3 1.5

3.3 2.5

3.3 3.5

3.3 4.5

3.3 5.5

4.5 0.8

4.5 1.5

4.5 2.5

4.5 3.5

4.5 4.5

4.5 5.5

CODE DIAM. LENGTH4.8 0.8

4.8 1.5

4.8 2.5

4.8 3.5

4.8 4.5

4.8 5.5

Angled multi-unit abutment*

Straight multi-unit abutment

DIAM. LENGTH3.5 0.8

3.5 1.5

3.5 2.5

3.5 3.5

3.5 4.5

CODE

CODE

CODE CODE

CODE

CODECODE CODE

CODE

For angled multi-unit

For straight multi-unit

CODE

Cobalt-chrome

Plastic

CODE

CODE

Healing cap

Micro multi-unit Abutment

CODE DIAM. LENGTH4.8 1.5

4.8 2.5

4.8 3.5

4.8 1.5

4.8 2.5

4.8 3.5

ANG.17º

17º

17º

30º

30º

30º

Abutment protector

Open tray transfer

Analog

CODE

PPMM 33

Abutment protector

Open tray transfer


Polishing protector

Polishing protector


Temporary titanium cylinder

Analog



CPM 4800-2 For angled multi-unit

CPM 4800-3 For straight multi-unit

CLEM 4800-2 Cobalt-chrome/For angled multi-unit

CLEM 4800-3 Cobalt-chrome/For straight multi-unit

15 N.cm

20 N.cm

10 N.cm

10 N.cm

10 N.cm

10 N.cm

CODE

CODE10 N.cm

20 N.cm


PRIM

E

CODE DIAM. LENGTH

3.5 8.5

3.5 10.0

3.5 11.5

3.5 13.0

3.5 15.0

4.3 8.5

4.3 10.0

4.3 11.5

4.3 13.0

4.3 15.0

5.0 8.5

5.0 10.0

5.0 11.5

5.0 13.0

5.0 15.0


UCM 3585N

UCM 3510N

UCM 3511N

UCM 3513N

UCM 3515N

UCM 4385N

UCM 4310N

UCM 4311N

UCM 4313N

UCM 4315N

UCM 5085N

UCM 5010N

UCM 5011N

UCM 5013N

UCM 5015N

CIMU 3308

CIMU 3315

CIMU 3325

CIMU 3335

CIMU 3345

CIMU 3355

CIMU 4508

CIMU 4515

CIMU 4525

CIMU 4535

CIMU 4545

CIMU 4555

MAMU 4808

MAMU 4815

MAMU 4825

MAMU 4835

MAMU 4845

MAMU 4855

MAMA 1715

MAMA 1725

MAMA 1735

MAMA 3015

MAMA 3025

MAMA 3035

CODEMMAM 3308

MMAM 3315

MMAM 3325

MMAM 3335

MMAM 3345

PMM 33 TMM 33 AMMA 33

TMFM 4800

ANMA 4800

TMAM 4800

P MA 4855

PTM 4800-2

PTM 4800-3

PPM 01

CPMT 33

CPMC 33

CPMM 33

PTMMA 14

PRH 3035

Hex Screw


Squared Screw

Abutment Screw


UNITITE PRIMEMULTI-UNIT ABUTMENTSMULTIPLE SCREW RETAINED RESTORATIONS

16 17

Overdenturebar

13mmØ 1.95mm

Ø 4.2mm

CODE DIAM. LENGTH

MAMU 4808 4.8 0.8

MAMU 4815 4.8 1.5

MAMU 4825 4.8 2.5

MAMU 4835 4.8 3.5

MAMU 4845 4.8 4.5

MAMU 4855 4.8 5.5

DIAM. CODE LENGTH

CIMU 3308 3.3 0.8

CIMU 3315 3.3 1.5

CIMU 3325 3.3 2.5

CIMU 3335 3.3 3.5

CIMU 3345 3.3 4.5

CIMU 3355 3.3 5.5

CIMU 4508 4.5 0.8

CIMU 4515 4.5 1.5

CIMU 4525 4.5 2.5

CIMU 4535 4.5 3.5

CIMU 4545 4.5 4.5

CIMU 4555 4.5 5.5

CODE

PMA 4855

CODE

TMFM 4800

CODE

ANMA 4800

CODE

FO 01

CODE

CLIPP

CODE

TMAM 4800Healing cap

Straight multi-unitabutment


CODE DIAM. LENGTH

3.5 8.5

3.5 10.0

3.5 11.5

3.5 13.0

3.5 15.0

4.3 8.5

4.3 10.0

4.3 11.5

4.3 13.0

4.3 15.0

5.0 8.5

5.0 10.0

5.0 11.5

5.0 13.0

5.0 15.0

UCM 3585N

UCM 3510N

UCM 3511N

UCM 3513N

UCM 3515N

UCM 4385N

UCM 4310N

UCM 4311N

UCM 4313N

UCM 4315N

UCM 5085N

UCM 5010N

UCM 5011N

UCM 5013N

UCM 5015N

Abutmentprotector


Open traytransfer

Plastic clip

Angled multi-unit abutment*

Closed traytransfer

Analog

CODE

CLEM 4800-2 Cobalt-chromeFor angled multi-unit

CLEM 4800-3 Cobalt-chromeFor straight multi-unit

CPM 4800-2 PlasticFor angled multi-unit

CPM 4800-3 PlasticFor straight multi-unit

45mm

Ø 2.5mm

CODE DIAM. LENGTH

4.8 1.5

4.8 2.5

4.8 3.5

4.8 1.5

4.8 2.5

MAMA 1715

MAMA 1725

MAMA 1735

MAMA 3015

MAMA 30254.8 3.5

ANG.

17°

17°

17°

30°

30°30°MAMA 3035

15 N.cm

10 N.cm

20 N.cm


PRIM

E

Hex Screw


Squared Screw

Abutment Screw


UNITITE PRIMEOVERDENTURE SOLUTIONSMULTI-UNIT + BAR-CLIP RESTORATIONS

18 19

UNITITE PRIMEOVERDENTURE SOLUTIONSO´RING ATTACHMENT

Open traytransfer

Abutment O’Ring

O’Ring attachment torque driver

O’Ring attachment hand driver

O’Ring insert hand driver

O’Ring removal hand driver


DIAM. LENGTH

3.5 8.5

3.5 10.0

3.5 11.5

3.5 13.0

3.5 15.0

4.3 8.5

4.3 10.0

4.3 11.5

4.3 13.0

4.3 15.0

5.0 8.5

5.0 10.0

5.0 11.5

5.0 13.0

5.0 15.0

CODE

UCM 3585N

UCM 3510N

UCM 3511N

UCM 3513N

UCM 3515N

UCM 4385N

UCM 4310N

UCM 4311N

UCM 4313N

UCM 4315N

UCM 5085N

UCM 5010N

UCM 5011N

UCM 5013N

UCM 5015N

Healing cap Analog

CODE DIAM. LENGTH

CIMU 3308 3.3 0.8

CIMU 3315 3.3 1.5

CIMU 3325 3.3 2.5

CIMU 3335 3.3 3.5

CIMU 3345 3.3 4.5

CIMU 3355 3.3 5.5

CIMU 4508 4.5 0.8

CIMU 4515 4.5 1.5

CIMU 4525 4.5 2.5

CIMU 4535 4.5 3.5

CIMU 4545 4.5 4.5

CIMU 4555 4.5 5.5

CODE

TMAMU

CODE

ANMU

CODE DIAM. LENGTH

AOM 4815 4.0 1.5

AOM 4825 4.0 2.5

AOM 4835 4.0 3.5

AOM 4845 4.0 4.5

CODECCAO 20

CCAO 24

CODECDAO 20

CDAO 24

CODEMOR

CODEROR

Titanium cap+O’Ring O’Ring Directional

rings

CODE

AFROM

CODE

OCAN

CODE

POS01 0º White

POS02 7º Yellow

POS03 14º Blue


CODE

TMFMU

20 N.cm

PRIM

E

Hex Screw


Squared Screw

Abutment Screw


*Coming soon. Check availability with your distributer.

20 21

Analog

Temporaryacrylic Cylinder

CODE DIAM. LENGTH

2.9 10.0

2.9 11.5

2.9 13.0

CODE DIAM. LENGTH

3.3 4.03.3 6.0

CODE DIAM. LENGTH

ASIT 3340 3.3 4.0

ASIT 3360 3.3 6.0

CODE DIAM. LENGTH

3.3 4.0

3.3 6.0

Healing cap

CODE DIAM. LENGTH

3.3 1.5

3.3 2.5

3.3 3.5

3.3 4.5


CEMENTATION LENGTH

3.3 0.8 4.0

3.3 1.5 4.0

3.3 2.5 4.0

3.3 3.5 4.0

3.3 4.5 4.0

3.3 5.5 4.0

3.3 0.8 6.0

3.3 1.5 6.0

3.3 2.5 6.0

3.3 3.5 6.0

3.3 4.5 6.0

3.3 5.5 6.0

Straight universal abutment

Calcinablepolyacetal cylinder

Suitable for late loading: As from 60 days.


Recommended 1.5 mm infra-bone installation.

Indicated for all type of bones.

Internal angle of 3°.


* In bone types I and II the bone tap is required to not exceed the recommended torque, and ensure the correct healing process.



Speed of the drill 2.7mm: 800 rpm.



15 N.cm

PolyacetalImpression Transfer

SLIM

Hex Screw


Squared Screw

Abutment Screw


UCMS 2910N

UCMS 2911N

UCMS 2913N

CIMUS 3315

CIMUS 3325

CIMUS 3335

CIMUS 3345

AISITS 334008

AISITS 334015

AISITS 334025

AISITS 334035

AISITS 334045

AISITS 334055

AISITS 336008

AISITS 336015

AISITS 336025

AISITS 336035

AISITS 336045

AISITS 336055

TSIT 3340TSIT 3360

CPSIT 3340

CPSIT 3360

CODE DIAM. LENGTH

3.3 4.0

3.3 6.0

CCSIT 3340

CCSIT 3360

UNITITE SLIMUNIVERSAL ABUTMENT - PRE-MADE POSTSCEMENTED RETAINED RESTORATIONS

22 23


3.5 1.5

3.5 2.5

3.5 3.5

CODE

PMM 33

CODE DIAM. LENGTH

CIMUS 3315 3.3 1.5

CIMUS 3325 3.3 2.5

CIMUS 3335 3.3 3.5

CIMUS 3345 3.3 4.5

CODE CODE

CODE

CPMC 33

CODE

PRH 3035 1.4

CODE

1.4

Abutment protector

Open traytransfer

PolishingprotectorAnalog


Laboratoryscrew

Retaining screw

LENGTH

LENGTH

CODE

PPMM 33

15 N.cm

10 N.cm

Hex Screw


Squared Screw

Abutment Screw


10 N.cm

10 N.cm

CPMM 33 Cobalt-chrome

SLIM

Healing cap Micro multi-unit Abutment

CODE DIAM. LENGTH

2.9 10.0

2.9 11.5

2.9 13.0


UCMS 2910N

UCMS 2911N

UCMS 2913N

MMAMS 3315

MMAMS 3325

MMAMS 3335

TMM 33 AMMA 33

CODE


CPMT 33

PTMMA 14

UNITITE SLIMMICRO MULTI-UNIT ABUTMENTMULTIPLE SCREW RETAINED RESTORATIONS

24 25

Temporaryacrylic cylinder

Calcinablepolyacetal cylinder


Recommended bone level installation.

Indicated for all type of bones

Internal angle of 4°


Polyacetal Impression Transfer Healing cap Straight universal abutment Analog

CODE DIAM. LENGTH

4.0 5.0

4.0 6.0

4.0 7.0

5.0 5.0

5.0 6.0

5.0 7.0

6.0 5.0

6.0 6.0

6.0 7.0

CODE DIAM. LENGTH

4.0 2.0

4.0 4.0

4.0 6.0

UCMC 4005N

UCMC 4006N

UCMC 4007N

UCMC 5005N

UCMC 5006N

UCMC 5007N

UCMC 6005N

UCMC 6006N

UCMC 6007N

Suitable for late loading: As from 60 days.

* In bone types I and II the bone tap is required to not exceed the recommended torque and ensure the correct healing process.

4.5 1.0 4.0

4.5 2.0 4.0

4.5 3.0 4.0

4.5 4.0 4.0

4.5 5.0 4.0

4.5 1.0 6.0

4.5 2.0 6.0

4.5 3.0 6.0

4.5 4.0 6.0

4.5 5.0 6.0


CEMENTATION LENGTH

AIMC 45401

AIMC 45402

AIMC 45403

AIMC 45404

AIMC 45405

AIMC 45601

AIMC 45602

AIMC 45603

AIMC 45604

AIMC 45605

CODE DIAM. LENGTH

TSIT 4540 4.5 4.0

TSIT 4560 4.5 6.0

CODE DIAM. LENGTH

4.5 4.0

4.5 6.0

CODE DIAM. LENGTH

CCSIT 4540 4.5 4.0

CCSIT 4560 4.5 6.0

CODE DIAM. LENGTH

4.5 4.0

4.5 6.0

ASIT 4540

ASIT 4560


Speed of the drills 2.7 to 5.8mm: 800 rpm.




20 N.cm

COM

PACT

CIC 4002

CIC 4004

CIC 4006

Hex Screw


Squared Screw

Abutment Screw


CPSIT 4540

CPSIT 4560

UNITITE COMPACTUNIVERSAL ABUTMENT - PRE-MADE POSTSCEMENTED RETAINED RESTORATIONS

26 27


Laboratory screw

Retainingscrew

PL 1405 Short

PTMA 13-1 Long

CODE

Healing cap Multi-unitAbutment

Analog

CODE DIAM. LENGTH

4.0 5.0

4.0 6.0

4.0 7.0

5.0 5.0

5.0 6.0

5.0 7.0

6.0 5.0

6.0 6.0

6.0 7.0

CODE DIAM.

CIC 4002 4.0

CIC 4004 4.0

CIC 4006 4.0

UCMC 4005N

UCMC 4006N

UCMC 4007N

UCMC 5005N

UCMC 5006N

UCMC 5007N

UCMC 6005N

UCMC 6006N

UCMC 6007N

CODE

CODE

TMAM 4800

CODE

TMFM 4800

2.0

4.0

6.0

LENGTH

MAC 4801 4.8 1.0

MAC 4802 4.8 2.0

MAC 4803 4.8 3.0

MAC 4804 4.8 4.0

MAC 4805 4.8 5.0


Abutmentprotector

Open tray transfer

Closed traytransfer

CODECODEANMA 4800

CODE

CPM 4800-3 For straight multi-unit

CLEM 4800-3 Cobalt-chrome/For straight multi-unit


CODE

PTM 4800 -3 For straight multi-unit


Polishing protector

CODE LENGTH

PRH 30 3.0

10 N.cm

10 N.cm

10 N.cm

COM

PACT

20 N.cm

PMA 4855

Hex Screw


Squared Screw

Abutment Screw


PPM 01

UNITITE COMPACTMULTI-UNIT ABUTMENTMULTIPLE SCREW RETAINED RESTORATIONS

28 29

DRILLING SEQUENCE GUIDE TECHNICAL INFORMATION

Unitite Compact

Unitite Prime

PLAT. (mm)

1.200 RPM 800 RPM 20 RPM

FRLD 2005

FHCD 2015

FUM 2915

FUM 3515

FUM 4315

FUM 5015

CMRU 35

CMRU 43

CMRU 50

3.5 ● ● ● ● ●

4.3 ● ● ● ● ● ●

5.0 ● ● ● ● ● ● ●

Unitite Slim

PLAT. (mm)

1.200 RPM 800 RPM 20 RPM

FRLD 2005 FHCD 2015 FUM 2915 CMRU 29

2.9 ● ● ● ●

Unitite Compact

PLAT. mm )

1.200 RPM 800 RPM 20 RPM

FRLD 2005

FHCD 2015

FUM 2915

FUM 3515

FHCD 3215

FHCD 4215

FHCD 5215

CMRUC 40

CMRUC 50

CMRUC 60

4.0 ● ● ● ● ● ●

5.0 ● ● ● ● ● ● ●

6.0 ● ● ● ● ● ● ● ●

(

2.50 11.5°

3.50

2.50 11.5°

4.30

2.50 11.5°

5

8.5mm10mm

11.5mm13mm15mm

1.8 2.3 3

UCM 35xxN UCM 43xxN UCM 50xxN

Hex. 2

Hex. 2

Hex. 2

3.50

4.30

5

UCMS 29xxN

3°

2

2.90

10mm11.5mm13mm

2.4

Qua

d. 1,3

0

2,90

03/01/2017

Unitite Slim 8:1Código: Escala:

Data:

mmUnidade

3° 2

2,90

10mm11,5mm13mm

2,4

UCMS 29xxN

Quad

. 1.30

2.90

03/01/2017


Data:

mmUnidade

2.50 4°

4

2.50 4°

5

2.50 4°

6

5mm6mm7mm

UCMC 40xxN UCMC 50xxN UCMC 60xxN

4 5 6

Hex. 2 Hex. 2 Hex. 2

2.50 11.5°

3.50

2.50 11.5°

4.30

2.50 11.5

° 5

8.5mm

10mm

11.5mm

13mm

15mm

1.8 2.3

3

UCM

35xxNU

CM 43xxN

UCM

50xxN

Hex. 2

Hex. 2

Hex. 2

3.50

4.30

5

UCM

S 29xxN

3° 2

2.90

10mm

11.5mm

13mm

2.4

Quad. 1,30

2,90

03/01/2017

Un

itite Slim8:1

Código:

Escala:

Data:

mm

Unidade

3° 2

2,90

10mm

11,5mm

13mm

2,4

UCM

S 29xxN

Quad. 1.30

2.90

03/01/2017

Un

itite Slim8:1

Código:

Escala:

Data:

mm

Unidade

2.50 4° 4

2.50 4° 5

2.50 4° 6

5mm

6mm

7mm

UCM

C 40xxNU

CMC 50xxN

UCM

C 60xxN

4 5

6

Hex. 2 Hex. 2

Hex. 2

2.50 11.5°

3.50

2.50 11.5°

4.30

2.50 11.5°

5

8.5mm10mm

11.5mm13mm15mm

1.8 2.3 3


Hex. 2

Hex. 2

Hex. 2

3.50

4.30

5

UCMS 29xxN

3°

2

2.90

10mm11.5mm13mm

2.4

Qua

d. 1,3

0

2,90

03/01/2017


Data:

mmUnidade

3° 2

2,90

10mm11,5mm13mm

2,4

UCMS 29xxN

Quad

. 1.30

2.90

03/01/2017


Data:

mmUnidade

2.50 4°

4

2.50 4°

5

2.50 4°

6

5mm6mm7mm


4 5 6


2.50 11.5°

3.50

2.50 11.5°

4.30

2.50 11.5°

5

8.5mm10mm

11.5mm13mm15mm

1.8 2.3 3


Hex. 2

Hex. 2

Hex. 2

3.50

4.30

5

UCMS 29xxN

3°

2

2.90

10mm11.5mm13mm

2.4

Qua

d. 1,3

0

2,90

03/01/2017


Data:

mmUnidade

3° 2

2,90

10mm11,5mm13mm

2,4

UCMS 29xxN

Quad

. 1.30

2.90

03/01/2017


Data:

mmUnidade

2.50 4°

4

2.50 4°

5

2.50 4°

6

5mm6mm7mm


4 5 6


2.50 11.5°

3.50

2.50 11.5°

4.30

2.50 11.5°

5

8.5mm10mm

11.5mm13mm15mm

1.8 2.3 3


Hex. 2

Hex. 2

Hex. 2

3.50

4.30

5

UCMS 29xxN

3°

2

2.90

10mm11.5mm13mm

2.4

Qua

d. 1,3

0

2,90

03/01/2017


Data:

mmUnidade

3° 2

2,90

10mm11,5mm13mm

2,4

UCMS 29xxN

Quad

. 1.30

2.90

03/01/2017


Data:

mmUnidade

2.50 4°

4

2.50 4°

5

2.50 4°

6

5mm6mm7mm


4 5 6


Unitite Prime Unitite Slim

For all implants, in bone types I and II the bone tap is required to not exceed the recommended torque and ensure the correct healing process.

Unitite Prime

PLAT. (mm)

1.200 RPM 800 RPM 20 RPM

FRLD 2005

FHCD 2015

FUM 2915

FUM 3515

FUM 4315

FUM 5015

CMRU 35

CMRU 43

CMRU 50

3.5 ● ● ● ● ●

4.3 ● ● ● ● ● ●

5.0 ● ● ● ● ● ● ●

Unitite Slim

PLAT. (mm)

1.200 RPM 800 RPM 20 RPM


2.9 ● ● ● ●

Unitite Compact

PLAT. mm )

1.200 RPM 800 RPM 20 RPM

FRLD 2005

FHCD 2015

FUM 2915

FUM 3515

FHCD 3215

FHCD 4215

FHCD 5215

CMRUC 40

CMRUC 50

CMRUC 60

4.0 ● ● ● ● ● ●

5.0 ● ● ● ● ● ● ●

6.0 ● ● ● ● ● ● ● ●

(

Unitite Prime

PLAT. (mm)

1.200 RPM 800 RPM 20 RPM

FRLD 2005

FHCD 2015

FUM 2915

FUM 3515

FUM 4315

FUM 5015

CMRU 35

CMRU 43

CMRU 50

3.5 ● ● ● ● ●

4.3 ● ● ● ● ● ●

5.0 ● ● ● ● ● ● ●

Unitite Slim

PLAT. (mm)

1.200 RPM 800 RPM 20 RPM


2.9 ● ● ● ●

Unitite Compact

PLAT. mm )

1.200 RPM 800 RPM 20 RPM

FRLD 2005

FHCD 2015

FUM 2915

FUM 3515

FHCD 3215

FHCD 4215

FHCD 5215

CMRUC 40

CMRUC 50

CMRUC 60

4.0 ● ● ● ● ● ●

5.0 ● ● ● ● ● ● ●

6.0 ● ● ● ● ● ● ● ●

(

30 31

ANN WENNERBERGWHAT THE SPECIALISTS SAY

DDS/PhD and Director of the Department of Dental Prosthesis at the Malmö University, Sweden. Specia-lized in Implant Surface and author of more than 220 scientific articles published in renowned magazines on this subject.

“Our research group has worked with the HAnano®

surface for over 10 years. Until now this research has resulted in two doctoral theses and another one is in progress. Our experimental results in 17 in vivo studies, mostly on rabbits, usually shows an improved bone response for the titanium with the HAnano® surface and PEEK implants when compared with implants without this surface.”

STUDIES

FÁBIO BEZERRAWHAT THE SPECIALISTS SAY

"Surface coating HAnano®, used in the Unitite implant, and 20 nanometers thick, homogeneously coating the en-tire surface, significantly increases surface energy, hy-drophilicity and scar response in the early stages of the Osseointegration process. The positive impact of its bio-availability has been demonstrated by different advan-ced methods of research, such as signal transduction and atomic force microscopy. Higher protein adsorption, as-sociated to a statistically significant presence of proteins related to the bone healing process in the presence of a biological catalyst for mineralization, make this surface one of the most advanced in the implants global market.”

A Graduate of Bauru School of Dentistry - USPSpecialist in Periodontics, Bauru School of Dentistry - USPSpecialist in Implantology by INEPO - SPMaster in Implantology by UNIP - São PauloDoctor in Biotechnology by IBB - UNESP

STUDIES

For original titles of the articles mentioned herein, please refer to the Scientific Publications page.

2

3

13

12

11

Functional evaluation of implants by bone mineralization in vitro.Lima JHC; Tanaka MN; Bezerra FJ; Maia VTG; Robbs PCMRev. bras. odontol., Rio de Janeiro, v. 72, n. 1/2, p. 92-5, jan./jun. 2015

Titanium-based dental implants favor cell-signaling pathway involved in the survival and proliferation of os-teoblasts.Bezerra FJ, Rossi MC, Fernandes CJC, Nascimento A, Ferreira MR, Zambuzzi WFInnov Implant J, Biomater Esthet. 2014;9(2/3):8-12

Microtomographic evaluation of a new nanometric hydroxyapatite covered implant surface. In vivo study in diabetic rats.Scombatti de Souza S, Oliveira P, Borges C, Reino D, Novaes Jr A, Taba Jr M, Bezerra FJ.Clin. Oral Impl. Res. 27 (Suppl. 13), 2016

Evaluation of a new nanometric hydroxyapatite covered implant surface. In vivo study in diabetic rats analy-sing osteogenesis gene expression.Oliveira P, Scombatti de Souza S, Sales M, Novaes Jr A, Palioto D, Messora M, Santos F, Bezerra FJ.Clin. Oral Impl. Res. 27 (Suppl. 13), 2016

Nano hydroxyapatite-blasted titanium surface affects pre-osteoblast morphology by modulating critical intra-cellular pathways.Bezerra FJ, Ferreira MR, Fontes GN, da Costa Fernandes C Jr; Andia DC, Cruz NC, da Silva RA; Zambuzzi WF. Biotechnol Bioeng. 2017 Apr 12

45

46

37

38

36

Genetic Responses to Nanostructured Calcium-phosphate-coated Implants.Jimbo R, Xue Y, Hayashi M, Schwartz-Filho HO, Andersson M, Mustafa K, Wennerberg A.J DENT RES published online 20 September 2011

Histological and three-dimensional evaluation of osseointegration to nanostructured calcium phosphate-coa-ted implants.Jimbo R, Coelho PG, Vandeweghe S, Humberto Osvaldo Schwartz-Filho HO, Hayashi M, Ono D, Andersson M, Wennerberg A.Acta Biomater. 2011 Dec;7(12):4229-34.

Nano hydroxyapatite-coated implants improve bone nanomechanical properties.Jimbo R, Coelho PG, Bryington M, Baldassarri M, Tovar N, Currie F, Hayashi M, Janal MN, Andersson M, Ono D, Vandeweghe S, Wennerberg A. J Dent Res. 2012;91(12):1172-7

The biological response to three different nanostructures applied on smooth implant surfaces.Jimbo R, Sotres J, Johansson C, Breding K, Currie F, Wennerberg A. Clin Oral Implants Res. 2012;23(6):706-12

The effect of chemical and nanotopographical modifications on the early stages of osseointegration.Meirelles L, Currie F, Jacobsson M, Albrektsson T, Wennerberg A. Int J Oral Maxillofac Implants. 2008 Jul-Aug;23(4):641-7

32 33

CTO of Promimic, Co-inventor of the HAnano® surface,PhD in Materials and Chemical Surfaces by the ChalmersUniversity in Gothenburg, Sweden, and author of severalstudies in the area of nanomaterials.

“The HAnano® surface is an ultrathin layer of synthetic bone on the surface of the implant. Each crystal of syn-thetic bone is extremely small, 10 to 14 nm in length and about 5nm in thickness. What makes these crystals so special is that they have the same size and shape as those found in human bone and are recognized by the bone cells, as well as by the bone tissue, which activates the catalyzer and starts a huge process of building bone around the implant. This effect has been proven in more than 20 pre-clinical studies with the best researchers in the world in the area of implants.”

PER KJELLIN WHAT THE SPECIALISTS SAY

STUDIES

Researcher in the Bme - KULeuven, Belgium. Post-PhD inBiomechanics by the FEMEC/UFU and Researcher in the Bme- KULeuven, Belgium. PhD in Periodontics/Dental Implant -FOAr/UNESP - Araraquara, Brazil. Master in Oral Rehabilitation- FOUFU - Uberlândia, Brazil.

"UNITITE implants have made the results of current major clinical demands more predictable, such as shortening the time between implant installation and final patient reha-bilitation, maintaining peri-implant bone height, which has a large impact on long-term aesthetic predictability and the rehabilitation of areas with poor bone availability in an efficient and minimally invasive way, in many cases avoiding the need for bone grafts. I am very flattered to have participated actively in this project. "

ROBERTO PESSOA WHAT THE SPECIALISTS SAY

STUDIES

1

4

5

7

Nano hydroxyapatite structures influence early bone formation.Meirelles L, Arvidsson A, Andersson M, Kjellin P, Albrektsson T, Wennerberg A. J Biomed Mater Res A. 2008 Nov;87(2):299-307

Bone reaction to nano hydroxyapatite modified titanium implants placed in a gap-healing model.Meirelles L, Albrektsson T, Kjellin P, Arvidsson A, Franke-Stenport V, Andersson M, Currie F, Wennerberg A. J Biomed Mater Res A. 2008 Dec 1;87(3):624-31

Effect of hydroxyapatite and titania nanostructures on early in vivo bone response.Meirelles L, Melin L, Peltola T, Kjellin P, Kangasniemi I, Currie F, Andersson M, Albrektsson T, Wennerberg A. Clin Implant Dent Relat Res. 2008 Dec;10(4):245-54

Evaluation of bone healing on sandblasted and acid etched implants coated with nanocrystalline hydroxyapa-tite: an in vivo study in rabbit femur.Svanborg LM, Meirelles L, Franke-Stenport V, Kjellin P, Currie F, Andersson M, Wennerberg A.International Journal of Dentistry 2014;2014:197581. Epub 2014 Mar 2

Bone Remodeling Around Implants with External Hexagon and Morse-Taper Connections: A Randomized, Con-trolled, Split-Mouth, ClinicalTrial.Pessoa RS, Sousa RM, Pereira LM, Neves FD, Bezerra FJ, Jaecques SV, Sloten JV, Quirynen M, Teughels W, Spin-Neto R.Clin Implant Dent Relat Res. 2017 Feb;19(1):97-110

Influence of implant design on the biomechanical environment of immediately placed implants: computed to-mography-based nonlinear three-dimensional finite element analysis.Pessoa RS, Coelho PG, Muraru L, Marcantonio Jr E, Vaz LG, Sloten JV, Jaecques SV. Int J Oral Maxillofac Implants. 2011 Nov-Dec;26(6):1279-87

Biomechanical evaluation of platform switching: different mismatch sizes, connection types, and implant pro-tocols.Pessoa RS, Bezerra FJ, Sousa RM, Vander Sloten J, Casati MZ, Jaecques SV.J Periodontol. 2014 Sep;85(9):1161-71

Influence of Connection Types and Implant Number on the Biomechanical Behavior of Mandibular Full-Arch Rehabilitation.Sousa RM, Simamoto-Junior PC, Fernandes-Neto AJ, Sloten JV, Jaecques SV, Pessoa RS. Int J Oral Maxillofac Implants. 2016 Jul-Aug;31(4):750-60

Influence of implant connection type on the biomechanical environment of immediately placed implants - CT--based nonlinear, three-dimensional finite element analysis.Pessoa RS, Muraru L, Júnior EM, Vaz LG, Sloten JV, Duyck J, Jaecques SV.Clin Implant Dent Relat Res. 2010 Sep;12(3):219-34.

30

26

34

29

35

For original titles of the articles mentioned herein, please refer to the Scientific Publications page.

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SCIENTIFIC PUBLICATIONSNano hydroxyapatite structures influence early bone formation.Meirelles L, Arvidsson A, Andersson M, Kjellin P, Albrektsson T, Wennerberg A. J Biomed Mater Res A. 2008 Nov;87(2):299-307

The effect of chemical and nanotopographical modifications on the early stages of osseointegration. Meirelles L, Currie F, Jacobsson M, Albrektsson T, Wennerberg A. Int J Oral Maxillofac Implants. 2008 Jul-Aug;23(4):641-7

Nano hydroxyapatite-coated implants improve bone nanomechanical properties. Jimbo R, Coelho PG, Bryington M, Baldassarri M, Tovar N, Currie F, Hayashi M, Janal MN, Andersson M, Ono D, Vandeweghe S, Wennerberg A. J Dent Res. 2012;91(12):1172-7

Effect of hydroxyapatite and titania Nanostructures on early in vivo bone response.Meirelles L, Melin L, Peltola T, Kjellin P, Kangasniemi I, Currie F, Andersson M, Albrektsson T, Wennerberg A. Clin Implant Dent Relat Res. 2008 Dec;10(4):245-54

Evaluation of bone healing on sandblasted and acid etched implants coated with nanocrystalline hydroxyapa-tite: an in vivo study in rabbit femur. Melin Svanborg L, Meirelles L, Franke-Stenport V, Kjellin P, Currie F, Andersson M, Wennerberg A.International Journal of Dentistry 2014;2014:197581.

Classification of osseointegrated implant surfaces: materials, chemistry and topography. Donhan Ehrenfest DM, Coelho PG, Kang BS, Sul YT, Albrektsson T. Trends Biotechnol. 2010 Apr;28(4):198-206

Bone reaction to nano hydroxyapatite modified titanium implants placed in a gap-healing model.Meirelles L, Albrektsson T, Kjellin P, Arvidsson A, Franke-Stenport V, Andersson M, Currie F, Wennerberg A. J Biomed Mater Res A. 2008 Dec 1;87(3):624-31

Nanohydroxyapatite-coated PEEK implants: a pilot study in rabbit bone. Barkarmo S, Wennerberg A, Hoffman M, Kjellin P, Breding K, Handa P, Stenport V. J Biomed Mater Res A. 2013 Feb;101(2):465-71

An in vitro comparison of possibly bioactive titanium implant surfaces.Göransson A, Arvidsson A, Currie F, Franke-Stenport V, Kjellin P, Mustafa K, Sul YT, Wennerberg A. J Biomed Mater Res A. 2009 Mar 15;88(4):1037-47

Formation of calcium phosphates on titanium implants with four different bioactive surface preparations. An in vitro study.Arvidsson A, Franke-Stenport V, Andersson M, Kjellin P, Sul YT, Wennerberg A. J Mater Sci Mater Med. 2007 Oct;18(10):1945-54.

The biological response to three different nanostructures applied on smooth implant surfaces. Jimbo R, Sotres J, Johansson C, Breding K, Currie F, Wennerberg A. Clin Oral Implants Res. 2012;23(6):706-12

Genetic Responses to nanostructured calcium-phosphate-coated Implants.Jimbo R, Xue Y, Hayashi M, Schwartz-Filho HO, Andersson M, Mustafa K, Wennerberg A.J DENT RES published online 20 September 2011

Histological and three-dimensional evaluation of osseointegration to nanostructured calcium phosphate-coated implants.Jimbo R, Coelho PG, Vandeweghe S, Humberto Osvaldo Schwartz-Filho HO, Hayashi M, Ono D, Andersson M, Wennerberg A.Acta Biomater. 2011 Dec;7(12):4229-34.

Precipitation of calcium phosphate in the presence of albumin on titanium implants with four different possi-bly bioactive surface preparations. An in vitro study. Stenport V , Kjellin P, Andersson M, Currie F, Sul Y-T, Wennerberg A, Arvidsson A.J Mater Sci: Mater Med. 2008;19:3497–505

Nucleation and growth of calcium phosphates in the presence of fibrinogen on titanium implants with four poten-tially bioactive surface preparations. an in vitro study. Arvidsson A, Currie F, Kjellin P, Sul YT, Stenport V. J Mater Sci Mater Med. 2009 Sep;20(9):1869-79

Early bone healing and biomechanical fixation of dual acidetched and as-machined implants with healing cham-bers: an experimental study in dogs. Bonfante EA, Granato R, Marin C, Suzuki M, Oliveira SR, Giro G, Coelho PG.Int J Oral Maxillofac Implants. 2011 Jan-Feb;26(1):75-82

Osseointegration: hierarchical designing encompassing the macrometer, micrometer, and nanometer length scales. Coelho PG, Jimbo R, Tovar N, Bonfante EA. Dent Mater. 2015;31(1):37-52

Are insertion torque and early osseointegration proportional? A histologic evaluation. Baires-Campos FE, Jimbo R, Bonfante EA, Barbosa DZ, Oliveira MT, Janal MN, Coelho PG. Clin Oral Implants Res. 2015 Nov;26(11):1256-60.

Fracture strength and probability of survival of narrow and extra-narrow dental implants after fatigue testing: In vitro and in silico analysis. Bordin D, Bergamo ETP, Fardin VP, Coelho PG, Bonfante EA.J Mech Behav Biomed Mater. 2017 Jul;71:244-249

Drilling dimension effects in early stages of osseointegration and implant stability in a canine model. Baires-Campos FEB, Jimbo R, Bonfante EA, Oliveira MTF, Moura C, Barbosa DZ, Coelho PG.Med Oral Patol Oral Cir Bucal. 2015 Jul 1;20(4):e471-9

Osseointegration of metallic devices: current trends based on implant hardware design. Coelho PG, Jimbo R. Archives of biochemistry and biophysics. 2014;561:99-108

Buccal and lingual bone level alterations after immediate implantation of four implant surfaces: a study in dogs. Bonfante EA, Janal MN, Granato R, Marin C, Suzuki M, Tovar N, Coelho PG. Clin Oral Implants Res. 2013 Dec;24(12):1375-80

Alveolar buccal bone maintenance after immediate implantation with a surgical flap approach: a study in dogs. Coelho PG, Marin C, Granato R, Bonfante EA, Lima CP, Oliveira S, Dohan Ehrenfest DM, Suzuki M. The International Journal of Periodontics & Restorative Dentistry 2011;31:e80–e86

Influence of clinically relevant factors on the immediate biomechanical surrounding for a series of dental im-plant designs. Shunmugasamy VC, Gupta N, Pessoa RS, Janal MN, Coelho PG. J Biomech Eng. 2011;133(3):031005

Basic research methods and current trends of dental implant surfaces.Coelho PG, Granjeiro JM, Romanos GE, Suzuki M, Silva NR, Cardaropoli G, Thompson VP, Lemons JE. J Biomed Mater Res B Appl Biomater. 2009;88(2):579-96

Influence of implant design on the biomechanical environment of immediately placed implants: computed to-mography-based nonlinear three-dimensional finite element analysis. Pessoa RS, Coelho PG, Muraru L, Marcantonio Jr E, Vaz LG, Sloten JV, Jaecques SV. Int J Oral Maxillofac Implants. 2011 Nov-Dec;26(6):1279-87

Fatigue reliability of three single-unit implant-abutment designs. Martins LM, Martins LM, Bonfante EA, Zavanelli RA, Freitas AC Jr, Silva NR, Marotta L, Coelho PG. Implant Dent. 2012 Feb;21(1):67-71

Immediate or early loading of implants with healing chambers and nano-surface: a non-interferential longitudi-nal prospective studyCarregamento funcional imediato ou precoce de implantes com câmara de cicatrização e superfície nanométrica: estudo clínico prospectivo longitudinal.Bezerra FJ, Pessoa RS, Zambuzzi WF.Innov Implant J, Biomater Esthet. 2014;9(2/3):13-7

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SCIENTIFIC PUBLICATIONSInfluence of connection types and implant number on the biomechanical behavior of mandibular full-arch rehabilitation. Sousa RM, Simamoto-Junior PC, Fernandes-Neto AJ, Sloten JV, Jaecques SV, Pessoa RS. Int J Oral Maxillofac Implants. 2016 Jul-Aug;31(4):750-60

Bone remodeling around implants with external hexagon and morse-taper connections: a randomized, control-led, split-mouth, clinical trial.Pessoa RS, Sousa RM, Pereira LM, Neves FD, Bezerra FJ, Jaecques SV, Sloten JV, Quirynen M, Teughels W, Spin-Neto R.Clin Implant Dent Relat Res. 2017 Feb;19(1):97-110

Bone remodeling of implants with external hexagon connection and retention elements at the crestal module under immediate loading – a 1-year longitudinal prospective clinical trial.Remodelação óssea de implantes com conexão hexágono externo e elementos de retenção no módulo da crista sob car-regamento imediato – estudo clínico prospectivo longitudinal de um ano.Pessoa RS, Souza RM, Pereira LM, Neves FD, Jaecques SVN, Sloten JV, Quirynen M, Teughels W, Spin-Neto R. ImplantNews 2015;12(4):E2-E7

Soft and hard tissue maintenance following placement of immediate-loaded implants in the aesthetic zone: a prospective longitudinal clinical trial.Avaliação da estabilidade dos tecidos duros e moles em implantes imediatos com carga imediata em área estética: estudo clínico.Pessoa RS, Sousa RM, Pereira LM, Silva TD, Bezerra FJ, Spin-Neto R. Dental Press Implantol. 2015 Apr-Jun;9(2):100-9

Edentulism impact assessment and rehabilitation mandibular total fixed on implants with immediate loading in patients’ quality of life of elderly.Avaliação do impacto do edentulismo total mandibular e da reabilitação fixa sobre implantes com carga imediata na qualidade de vida de pacientes idosos.Bezerra FJ, Lenharo A, Pessoa RS, Duarte LRS, Granjeiro JM. Rev Dental Press Periodontia Implantol. 2011 jul-set;5(3):101-10

Biomechanical evaluation of platform switching: different mismatch sizes, connection types, and implant protocols.Pessoa RS, Bezerra FJ, Sousa RM, Vander Sloten J, Casati MZ, Jaecques SV.J Periodontol. 2014 Sep;85(9):1161-71

Influence of implant connection type on the biomechanical environment of immediately placed implants - CT--based nonlinear, three-dimensional finite element analysis.Pessoa RS, Muraru L, Júnior EM, Vaz LG, Sloten JV, Duyck J, Jaecques SV.Clin Implant Dent Relat Res. 2010 Sep;12(3):219-34.

Nano hydroxyapatite-blasted titanium surface affects pre-osteoblast morphology by modulating critical intra-cellular pathways.Bezerra FJ, Ferreira MR, Fontes GN, da Costa Fernandes C Jr; Andia DC, Cruz NC, da Silva RA; Zambuzzi WF. Biotechnol Bioeng. 2017 Apr 12

Microtomographic evaluation of a new nanometric hydroxyapatite covered implant surface. In vivo study in diabetic rats.Scombatti de Souza S, Oliveira P, Borges C, Reino D, Novaes Jr A, Taba Jr M, Bezerra FJ.Clin. Oral Impl. Res. 27 (Suppl. 13), 2016

Evaluation of a new nanometric hydroxyapatite covered implant surface. In vivo study in diabetic rats analysing osteogenesis gene expression.Oliveira P, Scombatti de Souza S, Sales M, Novaes Jr A, Palioto D, Messora M, Santos F, Bezerra FJ.Clin. Oral Impl. Res. 27 (Suppl. 13), 2016

Biofilm formation on nanostructured hydroxyapatite-coated titanium.Westas E, Gillstedt M, Lönn-Stensrud J, Bruzell E, Andersson M.Biomed Mater Res A. 2014 Apr;102(4):1063-70

Nanocrystalline hydroxyapatite/titania coatings on titanium improves osteoblast adhesion. Sato M, Aslani A, Sambito MA, Kalkhoran NM, Slamovich EB, Webster TJ.J Biomed Mater Res. 2008;84A:265–72

Topography and surface energy of dental implants: a methodological approach.Barbosa TP, Naves MM, Menezes HHM, Pinto PHC, de Mello JDB, Costa HL. Journal of The Brazilian Society of Mechanical Sciences and Engineering 2017. June 2017, Volume 39, Issue 6, pp 1895–1907

Influence of macro-geometry in the primary stability of implants.Influência da macrogeometria na estabilidade primária dos implantes.Bezerra FJ, Ribeiro EP, Bittencourt S, Lenharo A.Innov Implant J 2010; 5:29-34

Influence of implant geometry on primary stability at diferent bone density.Influência da macrogeometria na estabilidade primária dos implantes em diferentes densidades ósseas.Bezerra FJ, Ribeiro EP, Bittencourt S, Lenharo A. Implant News 2010;7(5):671-6.

A multi-center prospective longitudinal study evaluating the clinical success rates of osseointegrated implants with a new macro-geometry: 6 to 12 months follow-up.Estudo prospectivo longitudinal multicêntrico avaliando o sucesso clínico de uma nova macrogeometria de implantes osseointegráveis: acompanhamento de 06 a 12 meses.Lenharo A, Granjeiro JM, Leão L, Bezerra FJ, Oliva MA. Revista Fluminense de Odontologia 2010; 34: 43-48

Functional evaluation of implants by bone mineralization in vitro.Avaliação funcional de implantes por mineralização óssea in vitro.Lima JHC; Tanaka MN; Bezerra FJ; Maia VTG; Robbs PCMRev. bras. odontol., Rio de Janeiro, v. 72, n. 1/2, p. 92-5, jan./jun. 2015

Titanium-based dental implants favor cell-signaling pathway involved in the survival and proliferation of os-teoblasts.Implantes dentários à base de titânio favorecem via de sinalização celular envolvidas com sobrevivência e proliferação de osteoblastosBezerra FJ, Rossi MC, Fernandes CJC, Nascimento A, Ferreira MR, Zambuzzi WFInnov Implant J, Biomater Esthet. 2014;9(2/3):8-12

Influence of operador experience on primary stability of implants with different geometry: in vitro study.Influência da experiência do operador na estabilidade primária de implantes com diferentes macrogeometrias – estudo in vitro.Bezerra FJ, Ribeiro EDP, Bittencourt S, Lenharo A.IJD, Int. j. dent. 2010, vol.9, n.2, pp. 63-67. ISSN 1806-146X.

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ABOUT US

Established in 2003, S.I.N. Implant System is one of the largest dental implant companies in the global market today, with 700,000 implants sold annually, offering a wide range of pro-ducts and with a strong global presence.

The combination of the latest in cutting-edge technologies with results of scientific investigations conducted alongside the world's leading dentistry universities has led us to produce sim-ple solutions that meet the needs of our customers, simplify processes, leading to a positive and safe experience for both professional and patient.

There are hundreds of publications and in-ternational research studies; in addition to trials conducted in over 40 universities.

Our factory is equipped with more than 50 imported lathes with the latest tech-nology and manufactures a total 5 million products per year.

We maintain a strict control process, pro-ven by national and international certifi-cations, in order to guarantee quality.

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