1.prevention and treatment of surgical infection

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    INTRODUCTION

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    The risk factors for developing awound infection

    The preoperative (prehospital) component The operative environment

    The microbial factors

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    CLASSIFICATION OF SURGICAL WOUNDS

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    CLASSIFICATION OF SURGICAL WOUNDS

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    Classification of Operative Wounds

    and Surgical infection rates

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    Health care-associated infection (HAI) /Nosocomial Infections in Surgical Patients

    Potential sites: UTIs Pneumonia surgical site (wound) infections (SSIs) bloodstream infection bacteremia

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    Principles Of Prevention To Infection

    Preoperative Shower Remote-Site Infection and Shaving Hand Washing Shoe Covers, Caps, Masks, Gowns, and Gloves Core Body Temperature Postoperative Care Surgical Wound Management and Surgical

    Wound Infection Care

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    Remote-Site Infection and Shaving

    The presence of a remote-site infection,whether it is a pustule, an upper respiratoryinfection, or urinary tract infection, needs to beidentified and treated prior to any surgicalintervention

    A patient whose surgical site has been shavedhas an infection rate two to three times higher than patients who are not shaved

    The need for shaving a surgical site should beconsidered not for sanitary reasons but only forthe convenience of the patients wound care .

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    Hand Washing

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    Shoe Covers, Caps, Masks, Gowns,

    and Gloves

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    Core Body Temperature

    The presence of the cold environment in theoperating room reduces the patients core bodytemperature

    This reduction in the patients core temperaturesignificantly increases the risk of postoperativeinfection

    This requires meticulous attention to keeping thepatient warm

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    Postoperative Care

    Supportive therapy Monitoring Postoperative Fever

    Blood and radiographic tests Surgical Wound Management

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    Surgical Wound Management and

    Surgical Wound Infection Care Topical Wound Treatment

    CLOSED WOUNDS

    OPEN WOUNDS

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    Closed wound

    Healing by primary intention Closed wounds should be kept sterile for 24-48 h until

    epithelialization is complete Tensile strength is only 200/0 of normal skin at 3 weeks

    when collagen cross-linking is becoming significant. At 6weeks, wounds are at 70% of the tensile strength of normalskin, which is nearly the maximal tensile strength achievedby scar (75%-80% of normal).

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    Open Wound Necrotic material should be removed Open wounds heal optimally in a moist, sterile environment The wound is open, and the edges are not approximated The suture closed as delayed primary closure after 2 5 days These wounds heal by contraction and epithelialization.

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    Secondary closure of wound

    The wound is open, and the edges are not approximated. A

    potentially contaminated wound is best left open lightly packedwith damp saline soaked gauze and the suture closed as delayedprimary closure after 2 5 days

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    MICROBIAL FACTORS OF IMPORTANCE IN

    THE DEVELOPMENT OF INFECTION

    Two major reservoirs :(1) host endogenous microflora

    (2) microbes within the external milieu, whichoften represents the nosocomialenvironment for hospitalized individuals

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    Prophylactic antibiotics Empirical cover against expected pathogens with local

    hospital guidelines Single-shot intravenous administration at induction of

    anaesthesia

    Repeat only in prosthetic surgery, long operations or ifthere is excessive blood loss Continue as therapy if there is unexpected

    contamination Patients with heart valve disease or a prosthesis should

    be protected from bacteraemia caused by dental work,urethral instrumentation or visceral surgery

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    Prophylactic antibiotics

    Medical considerations that compromise thehealing capacity or increase the infection risk :

    Diabetes Peripheral vascular disease Possibility of gangrene or tetanus Immunocompromise

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    Prophylactic antibiotics

    High-risk wounds or situations: Penetrating wounds Abdominal trauma Compound fractures Wounds with devitalized tissue Lacerations greater than 5 cm or stellate lacerations

    Contaminated wounds High risk anatomical sites such as hand or foot Biliary and bowel surgery.

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    Antibiotic Therapy

    A narrow-spectrum antibiotic may be used totreat a known sensitive infection

    Combinations of broad-spectrum antibioticscan be used when the organism is not known

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    Principles for the use of antibiotictherapy

    Antibiotics do not replace surgical drainage ofinfection

    Only spreading infection or signs of systemic

    infection justifies the use of antibiotics Whenever possible, the organism and sensitivity

    should be Determined

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    HIV, AIDS AND THE SURGEON

    Involvement of surgeons with HIV patients(universal precautions):

    use of a full face mask ideally, or protective spectacles; use of fully waterproof, disposable gowns and drapes,particularly during seroconversion; boots to be worn, not clogs, to avoid injury from dropped

    sharps; double gloving needed allow only essential personnel in theatre; avoid unnecessary movement in theatre; respect is required for sharps, with passage in a kidney dish; a slow meticulous operative technique is needed with

    minimised bleeding .

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    Thank You