1st Joint Meeting

14th International Congressfor Bioengineering and the Skin

and

8th Congress of the InternationalSociety for Skin Imaging

Hamburg, May 21-24, 2003

Program

1Cover-Picture: © Tourismus-Zentrale Hamburg GmbH

TABLE OF CONTENTS

Imprint

PublisherProfessor Dr. Klaus-P. WilhelmproDERM Institute for Applied Dermatological Research GmbHIndustriestr. 1, 22869 Schenefeld/Hamburg, Germany

Publishing houseWecom Gesellschaft für Kommunikation mbH & Co. KGLerchenkamp 11, 31137 Hildesheim, GermanyTelefon ++49 (0) 51 21/20 666-0, Fax ++49 (0) 51 21/20 666-02E-Mail: info@we-com.org

The publishing house does not take over guarantee for the correctness of the data.

Layout & sentencetypotime Digitale Druckvorlagenherstellung GbRIn den Sieben Äckern 2, 31162 Bad Salzdetfurth, GermanyTelefon ++49 (0) 50 64/8 55 14, Fax ++49 (0) 50 64/8 55 15E-Mail: info@typotime.de

Date of print: April 1, 2003

Invitation ......................................................................................................................... 2Greeting word................................................................................................................. 3Contacts .......................................................................................................................... 4Program at a Glance ...................................................................................................... 6Program ........................................................................................................................ 10Posters........................................................................................................................... 27Index of authors ........................................................................................................... 35General Information ..................................................................................................... 40City of Hamburg ........................................................................................................... 45Social program ............................................................................................................. 47Social Events ................................................................................................................ 48Hotel Reservation Form ............................................................................................... 49List of Sponsors............................................................................................................ 52List of Exhibitors........................................................................................................... 53Exhibition Floor Plan .................................................................................................... 54City Map ........................................................................................................................ 55

2

INVITATION

DEAR COLLEAGUES,

it is my great pleasure to invite you on behalf of theOrganizing Committee to this first joint meeting of twoscientific societies focussing on measurement andvisualization of skin function, structure and physiology: theInternational Society for Bioengineering and the Skin (ISBS)and the International Society for Skin Imaging (ISSI), to beheld in Hamburg, May 21-24, 2003.

ISBS and ISSI focus on neighbouring research topics andshare since 1995 a successful common official journal: SkinResearch and Technology.

This first joint meeting will truly be very stimulating by this interaction and willcertainly further increase attention to the facinating and rapidly developing field ofskin bioengineering and imaging.

It is the aim of this meeting to stimulate discussion between clinicians, engineers,basic and industrial researchers, to exchange ideas and to make and renewfriendships.

Hamburg is truly one of the most beautiful cities in Germany. Although stillunknown to many foreign tourists Hamburg has to offer an unparalleled, excitingmixture of world city culture, harbour flair, Alster romance and townscape full ofparks and tree-lined boulevards.

The CCH Convention Center is located in the heart of the city, allowing you toexplore many of the city attractions by foot.

We look forward to your participating in this exciting event.

Klaus-P. WilhelmChairman of the Organizing Committee

3

GREETING WORD

LADIES AND GENTLEMEN,

as the Minister for Science and Research and on behalf ofthe government it is my great pleasure to welcome you allto the Free and Hanseatic City of Hamburg. We feel proudand honored to host this international conference. I am surethat Hamburg will present itself at its best and will contrib-ute our experience as an international science and businesscentre.

Within the next four days scientists, physicians andengineers will engage in an exchange on the latest findingsin the field of skin bioengineering and imaging. The topicsbioengineering, medical technology and basic and appliedmedical research are also important for the city of Hamburg. Our scientific andeconomic policy aims at strengthening our know-how in the field of life sciencesand thus contributing further to our development as a competitive and successfullife science centre in Europe. The perspectives for this are excellent. We have witha sound mixture of medical- and biotech-companies, excellent medical andbiological research institutes and well known hospitals such as the UniversityHospital Eppendorf the right environment for this development. It is of specialconcern to me as the Minister for Science and Research to further the alreadyexisting potential of Hamburg by supporting international meetings like this tobring so many internationally renowned experts to our city.

I would like to express my gratitude to Prof. Dr. Klaus-P. Wilhelm for organisingthis meeting and wish you all fruitful discussions, exciting scientific insights, andinteresting new contacts. But I hope that you will have here not only successfulconference days but will also take home something of the spirit of our beautifulcity.

Sincerely yours

Jörg Dräger, Ph.D.Minister for Science and Researchof the Free and Hanseatic City of Hamburg

4

CONTACTS

VenueCCH Congress Centrum HamburgAm Dammtor/Marseiller Straße20355 Hamburg

Organizing Committee

Klaus-P. Wilhelm, Schenefeld/Hamburg (D) (Chairman)Peter Elsner, Jena (D)Stephan El Gammal, Freudenberg (D)Howard I. Maibach, San Francisco (USA)Gert Nilsson, Linköping (S)Hubert Pehamberger, Wien (A)Randy Wickett, Cincinnati (USA)Walter Wigger-Alberti, Schenefeld/Hamburg (D)

Scientific Committee

Peter Elsner, Jena (D) (Chairman ISBS)Stephan El Gammal, Freudenberg (D) (Chairman ISSI)Bernard Gabard, Münchenstein (CH)Philippe Humbert, Besançon (F)Jean-Luc Lévêque, Paris (F)Jørgen Serup, Linköping (S)

Scientific Advisory Board

Members of the Board of the International Society for Bioengineer-ing and the Board of the International Society for Skin Imaging

Contact

Professor Dr. Klaus-P. WilhelmproDERMInstitute for Applied Dermatological Research GmbHIndustriestr. 122869 Schenefeld/HamburgPhone: ++49 (0) 40-83 93-58 17Fax: ++49 (0)40-83 93-58 39E-Mail: KPW@proderm.de

Administration Secretariat(before/after the congress)

AKM Congress Service GmbHHauptstr. 1879576 Weil am Rhein/GermanyPhone: ++49 (0) 7621-98 33 0Fax: ++49 (0) 7621-78 714E-Mail: akmweil@akmcongress.com

Congress Office (during congress)

1st Joint Meeting14th International Congressfor Bioengineering and theSkin and

8th Congress of theInternational Society for SkinImaging

c/o AKM Congress ServiceGmbHCCH Congress CentrumHamburgAm Dammtor/Marseiller Straße20355 HamburgPhone: ++49(0)40-3569-4230Fax: ++49(0)40-3569-3530

Language

English (without translation)

Internet

www.akm.ch/ISBS/ISSI2003

CONTACTS

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PROGRAM AT A GLANCE

WEDNESDAY, MAY 21Room 5 Room 9/10 Room 8

12:00-12:3012:30-13:0013:00-13:3013:30-14:00 Satellite14:00-14:30 Symposium14:30-15:00 Optiscan Pty. Ltd.15:00-15:30 (page 10)15:30-16:0016:00-16:3016:30-17:0017:00-17:3017:30-18:0018:00-18:30 Opening Ceremony18:30-19:00 Opening Lecture19:00-19:30 (page 12)19:30-20:0020:00-20:30 Welcome Reception20:30-21:00 on Rickmer Rickmers21:00- (page 12/48)

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PROGRAM AT A GLANCE

THURSDAY, MAY 22Room 6 Room 5

07:30-08:0008:00-08:3008:30-08:4508:45-09:05 Plenary I09:05-09:25 Optical Coherance09:25-09:40 Tomography and09:40-10:00 High Resolution10:00-10:15 Ultrasound10:15-10:30 (page 13)10:30-11:00 Coffee-Break / Poster / Exhibition11:00-11:20 Plenary II11:20-11:40 Skin11:40-11:55 Bioengineering11:55-12:10 New Developments I12:10-12:25 (page 14)12:30-13:00 Poster / Exhibition13:00-13:3013:30-14:0014:00-14:20 Plenary III14:20-14:40 In Vivo Confocal14:40-15:00 Microscopy and15:00-15:15 Skin Imaging15:15-15:30 (page 15)15:30-15:4515:45-16:15 Coffee-Break / Poster / Exhibition16:15-16:35 Symposium 1A Symposium 1B16:35-16:50 Friction & Elasticity Telemedicine and16:50-17:05 (page 16) Microdialysis17:05-17:20 (page 17)17:20-17:4517:45-18:00 Business Meeting18:00-18:30 of ISBS and ISSI18:30-19:00 (page 17)19:00-19:30

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PROGRAM AT A GLANCE

FRIDAY, MAY 23Room 6 Room 5 In the Poster Area

07:30-08:0008:00-08:3008:30-08:45 Plenary IV08:45-09:05 Skin Bioengineering09:05-09:25 New Developments09:25-09:40 II09:40-10:00 (page 18)10:00-10:15 Coffee-Break / Poster / Exibition10:15-10:3010:30-11:00 Symposium 2A Symposium 2B11:00-11:20 Imaging of Skin Claims Support11:20-11:40 Malignoma and in Cosmetology11:40-11:55 Inflammation and Pharmacology11:55-12:00 (page 19) (page 20)12:00-12:30 Poster / Exibition12:30-13:00 Lunch-Symposium13:00-13:30 GF-Messtechnik13:30-14:00 GmbH14:00-14:30 (page 21)14:30-14:40 Plenary V14:40-15:00 Poster Viewing15:00-15:15 (page 22)15:15-15:3015:30-15:45 Poster Discussion15:45-16:15 and Poster Prizes16:15-16:35 Coffee-Break / Poster / Exibition16:35-16:4516:45-17:05 Symposium 3A Symposium 3B17:05-17:20 Epiluminescence New Bioengineering17:20-17:45 Microscopy & Multi- Techniques17:45-18:00 modal Skin Imaging (page 24)18:00-18:05 (page 23)18:05-18:3018:30-19:3019:30-20:0020:00-20:30 Congress Dinner20:30-21:00 at Zippelhaus21:00- (page 24)

PROGRAM AT A GLANCE

SATURDAY, MAY 24Room 6

07:30-08:0008:00-08:3008:30-09:0009:00-09:20 Plenary VI09:20-09:40 MRI and Skin Surface09:40-09:55 Imaging09:55-10:10 (page 25)10:10-10:2510:25-10:4010:40-11:15 Coffee-Break11:15-11:30 Plenary VII11:30-12:00 Ultrasound and12:00-12:30 Functional Imaging12:30-12:45 (page 26)12:45-13:00 Closing13:00-13:30 Ceremony13:30-13:45 (page 26)13:45-14:00

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PROGRAM

CONFOCAL MICROSCOPY IN-VIVO IMAGING OF SKINLatest Advances in:Technology, Techniques & ApplicationsScientific Convener: Professor Jørgen Serup, Linköping UniversityHospital, Linköping, SwedenMeeting Chairs: Professor Jørgen Serup; Dr. Salvador Gonzalez,Massachusetts General Hospital

CLINICAL PRESENTATIONS

Introduction to Fluorescent and Reflective in-vivo confocal microscopicimagingM. Rajadhyaksha (USA)

Recent achievements in the field of fibre-optic Live Micro Imaging (LMI)S. Thomas (Australia)

Confocal microscopy imaging of normal skinL. Swindle (USA)

Correlation of confocal microscopy imaging and histologyK. Busam (USA)

Clinical applications of confocal microscopyS. Gonzalez (USA)

Confocal microscopy of pre-malignant and malignant skin diseasesA. Halpern (USA)

Live Micro Imaging of the cutaneous vasculatureK. Sauermann (Germany)

Confocal microscopy of bullous skin diseasesM. Fleming (USA)

WEDNESDAY, MAY 21, 2003 Room 9/10

12:30 - 17:30

Satellite Symposium

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PROGRAM

PRODUCT TESTING & BASIC RESEARCH APPLICATIONS

In-vivo confocal microscopy for monitoring the effect of anti-neoplastictherapy of BCCA. Torres (USA)

In-vivo confocal microscopy for testing of cosmetic productsM. Takahashi (Japan)

Application of in-vivo laser scanning microscopy in skin physiologyJ. Ladermann (Germany)

The use of live micro imaging to monitor skin barrier functionR. Isseroff (USA)

Confocal microscopy as an imaging tool in animal experimentationS. Watkins (USA)

Conclusion & inauguration of the in-vivo confocal microscopy of skininterest group under the patronage of the ISBS.J. Serup (Sweden)

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WEDNESDAY, MAY 21, 2003 Room 8

18:00 - 19:30

Opening CeremonyChair: S. El Gammal, Freudenberg, D; P. Elsner, Jena, D;K.-P. Wilhelm, Hamburg, D

18:00 Opening Ceremony

18:15 Opening lecture: p < 0.05! - So, what? 1H.-H. Dubben, University of Hamburg (Hamburg, D)

19:30 Shuttle bus to “Rickmer Rickmers” available (one way)

20:00 Welcome ReceptionMuseum Ship „Rickmer Rickmers“

(see page 48)

PROGRAM

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PROGRAM

THURSDAY, MAY 22, 2003 Room 6

08:45 - 10:30

Plenary I

Optical coherance tomography & high resolution ultrasoundChair: A. Knüttel, Mannheim, D; H. Ermert, Bochum, D

08:45 High resolution OCT and hydration imaging of the skin 2A. Knüttel, S. Bonev, A. Höpfner, ISIS optronics GmbH (Mannheim, D)

09:05 OCT of skin tumors and inflammatory diseases 3J. Welzel, C. Winter, University of Lübeck, 4optics AG (Lübeck, D)

09:25 High-resolution sonography of the epidermis 4S. El Gammal1, K. Kaspar1, M. Vogt2, H. Ermert21 Krankenhaus Bethesda (Freudenberg, D)2 Institut für Hochfrequenztechnik Ruhr-Universität (Bochum, D)

09:45 A high frequency ultrasound based system for spatially resolved 5imaging of skin elasticity in vivoM. Vogt1, S. Scharenberg2, R. Scharenberg2, K. Hoffmann3,P. Altmeyer3, H. Ermert11 Ruhr-University (Bochum, D)2 taberna pro medicum GmbH (Lüneburg, D)3 Dermatologic University Hospital (Bochum, D)

10:00 Ultrasound imaging and optical coherence tomography of skin: 6a comparisonA.M. Nuijs, S. Neerken, G.W. Lucassen, Philips Research,Personal Care Institute (Eindhoven, NL)

10:15 The use of fluorescence in-vivo confocal imaging in the evaluation of 7transdermal delivery methodsS. Thomas, E. Murr, P. Anikijenko, A. Reese, P. Delaney,Optiscan Pty Ltd (Notting Hill, AUS)

10:30 Coffee break, visit exhibition and posters

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PROGRAM

THURSDAY, MAY 22, 2003 Room 6

11:00 - 12:25

Plenary II

Skin bioengineering: New developments IChair: G. Pièrard, Liège, B; R. Wickett, Cincinnati, USA

11:00 Guidelines in skin bioengineering: are they useful, are they used? 8G. Pièrard, University Medical Center (Liège, B)

11:20 The follicular cast - new techniques 9A. Thielitz, H. Gollnick, Department of Dermatology and Venereology(Magdeburg, D)

11:40 Assessment of permeability barrier function measuring trans- 10epidermal water loss: comparing 3 closed-loop systems and4 open-loop systems in vivo and in vitroJ.W. Fluhr1, L. Bankova1, P.M. Elias2, K.R. Feingold21 Friedrich-Schiller-University (Jena, D)2 UCSF (San Francisco, USA)

11:55 Analysis of water in human skin and nails using a portable 11near-infrared spectrometerM. Egawa1, T. Fukuhara1, T. Hirao1, M. Takahashi1, Y. Ozaki21 Shiseido (Yokohama-shi, JP)2 Kwansei Gakuin University (Sanda-shi, JP)

12:10 Osmotic effects in human skin 12P.M. Vankemenade1, M.M.J. Houben21 Personal Care Institute, Philips Research (Eindhoven, NL)2 Eindhoven University of Technology (Eindhoven, NL)

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PROGRAM

THURSDAY, MAY 22, 2003 Room 6

14:00 - 15:45

Plenary III

In vivo confocal microscopy & skin imagingChair: S. Gonzalez, Boston, USA; J. Fluhr, Jena, D;C. Edwards, Cardiff, UK

14:00 Confocal microscopy for the evaluation of the skin disorders 13S. Gonzalez, Wellman Labs, MGH, Harvard Medical School(Boston, USA)

14:20 High resolution laser speckle perfusion imaging 14K.R. Forrester1, J. Tulip2, C. Stewart1, C. Leonard1, R.C. Bray11 University Of Calgary (Calgary, CAN)2 University Of Alberta (Edmonton, CAN)

14:40 Applications of multiphoton microscopes in skin imaging 15K. König, Friedrich Schiller University (Jena, D)

15:00 In vivo-subsurface deformation measurements in human epidermis 16F.M. Hendriks1, J.A.M. Schuurman1, D. Brokken2, C.W.J. Oomens1,F.P.T. Baaijens11 Eindhoven University of Technology,2 Philips Research Laboratories (Eindhoven, NL)

15:15 Fluorescence confocal microscopy of normal human skin and 17skin lesions in vivoL. Swindle1, M. Freeman1, B. Jones2, S. Thomas31 Gold Coast Hospital (Gold Coast, AUS)2 The Skin Centre (Benowa, USA)3 Optiscan Pty Ltd (Notting Hill, AUS)

15:30 Photographic scales documenting features of skin aging based 18on digital imagesF. Morizot1, S. Guehenneux1, C. Guinot1, E. Mauger1, M. Binder2,E. Tschachler11 C.E.R.I.E.S. (Neuilly Sur Seine, F)2 University of Vienna (Vienna, A)

15:45 Coffee break, visit exhibition and posters

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PROGRAM

THURSDAY, MAY 22, 2003 Room 6

16:15 - 17:45

Symposium 1 A

Friction & elasticityChair: R. Marks, Cardiff, UK; P. Humbert, Besançon, F

16:15 The frictional feel analyzer 19M. Takahashi, M. Egawa, T. Hirao, Shiseido Research Center(Yokohama, JP)

16:35 Finger perception metrology. Correlation between friction force 20and acoustic emissionF. Flament1, R. Vargiolu1, A. Mavon2, P. Humbert3, H. Zahouani11 Ecole Centrale de Lyon (Ecully, F)2 Laboratoires Pierre Fabre (Toulouse, F)3 Laboratoire d’Ingénierie Cutanée (Besançon, F)

16:50 Miniaturized probe for in vivo assessment of stratum corneum 21biomechanical properties by microtorsionV. Gillon1, G. Perié1, W. Seipel2, G. Pauly11 Laboratoires Sérobiologiques, Division de Cognis (Pulnoy, F)2 Care Chemicals, Cognis Deutschland GmbH & Co.KG (Düsseldorf, D)

17:05 Study of the mechanical properties of human skin using the 22shear wave propagation methodA. Barel, R. Lambrecht, P. Clarys, Vrije Universiteit Brussel(Brussels, B)

17:20 Transient sonoelastography: a new method for measuring skin 23mechanical propertiesT. Baldeweck1, J.L. Génisson2, C. Cornillon1, M. Tanter2, S. Catheline2,M. Fink2, B. Querleux11 L’Oréal Recherche (Aulnay-sous-bois, F)2 ESPCI-LOA, UMR CNRS 1503 (Paris, F)

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PROGRAM

THURSDAY, MAY 22, 2003 Room 5

16:15 - 17:45

Symposium 1 B

Telemedicine & microdialysisChair: M. Fleming, Milwaukee, USA; E. Benfeldt, Copenhagen, DK

16:15 Mobile, multimedia computing for improved clinicopathologic 24correlation in dermatopathologyM. Fleming, Medical College of Wisconsin (Milwaukee, USA)

16:30 Tele-education and storage of multimedia-data 25J. Tittelbach, U. Metzner, J. Präßler, P. Elsner, Friedrich SchillerUniversity Hospital (Jena, D)

16:45 Microdialysis: an update 26E. Benfeldt, University of Copenhagen Department of Dermatology(Copenhagen, DK)

17:05 A new in vitro microdialysis technique for the assessment of 27percutaneous absorption of hazardous substances at theworkplaceG. Korinth1, T. Göen2, K.H. Schaller1, H. Drexler11 University of Erlangen-Nuremberg (Erlangen D)2 University of Technology (Aachen, D)

17:20 Development and usage of an open internet platform for 28distributed image processing applied to dermoscopyJ. Guillod1, F. Decaillet2, P. Schmid-Saugeon1, R. Panizzon1,M. Kunt2, J.P. Thiran21 University Hospital (Lausanne, CH)2 Swiss Federal Institute of Technology (Lausanne, CH)

17:45 Business Meeting of ISBS and ISSI Room 6

18

PROGRAM

FRIDAY, MAY 23, 2003 Room 6

08:30 - 10:00

Plenary IV

Skin bioengineering: New developments IIChair: S. Dikstein, Jerusalem, IL; D. Miller, Dallas, USA

08:30 Use and misuse of bioengineering techniques in dermatology 29H.I. Maibach, University of California Medical School(San Francisco, USA)

08:55 Quality management in the skin bioengineering laboratory: 30a strategic approachK.P. Wilhelm, proDERM GmbH (Schenefeld, D)

09:15 The stratum corneum spy 31R. Marks, P. Dykes, Cutest Systems Ltd (Cardiff, UK)

09:30 The new technique and device for the measurement of skin 32elasticity by the non-contact compressed air type skin analyzer(CASA)O. Osanai, T. Fujimura, T. Tsugita, S. Akasaki, S. Moriwaki, K. Hori,Y. Takema, Kao Corporation (Tokyo, Tochigi, JP)

09:45 Assessment of attractive and adhesive properties of skin surface 33film by contact mechanics approachH. Zahouani, C. Pailler, R. Vargiolu, Ecole Centrale de Lyon (Ecully, F)

10:00 Coffee break, visit exhibition and posters

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PROGRAM

FRIDAY, MAY 23, 2003 Room 6

10:30 - 12:00

Symposium 2 A

Imaging of skin malignoma & inflammationChair: K. Hoffmann, Bochum, D; H. Pehamberger, Vienna, A

10:30 Diagnosis of skin cancer using image analytical tools and neural 34networks for classificationK. Hoffmann, Ruhr-University (Bochum, D)

10:50 How successful are the generally accepted criteria for classification 35for skin cancer?H. Pehamberger, University of Vienna (Vienna, A)

11:10 Objective assessment of involved area in patients with atopic 36dermatitisH.-C. Kim, H.-S. Oh, Y.-M. Yoon, J.-S. Moon, S.-Y. Park, C.-H. Oh,M.-G. Kim, Korea University (Seoul, KOR)

11:25 An approach to the discrimination of benign common nevi and 37malignant melanoma from two different views: wavelet textureanalysis versus co-occurrence matrixM. Wiltgen, A. Gerger, J. Smolle, University of Graz (Graz, A)

11:40 Automated tissue classification, lesional identification and pattern 38indicators of melanocytic skin tumors at the microscopic levelA. Gerger, J. Smolle, Department of Dermatology, University of Graz(Graz, A)

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PROGRAM

FRIDAY, MAY 23, 2003 Room 5

10:30 - 12:00

Symposium 2 B

Claims support in cosmetology and pharmacologyChair: J. Welzel, Lübeck, D; E. Berardesca, Rome, I

10:30 Ethics of skin bioengineering studies 39P. Elsner, Friedrich Schiller University (Jena, D)

10:50 The science of the score in dermatology 40L. Naldi, Ospedali Riuniti (Bergamo, I)

11:10 Development of active barrier skin creams that protect against 41chemical warfare agentsE.H. Braue, Jr., U.S. Army Medical Research Institute of ChemicalDefense (Aberdeen Proving Ground, USA)

11:25 Anti-inflammatory efficacy of Poria cocos in SLS induced irritant 42contact dermatitis and UVB-induced erythemaS.M. Fuchs1, C. Heinemann1, J.W. Fluhr1, S. Schliemann-Willers1,U. Gräfe2, P. Elsner11 Friedrich-Schiller-University (Jena, D)2 Hans-Knöll-Institute for Natural Products Research (Jena, D)

11:40 Evidence for the phenomenon of acquired cutaneous hyper- 43irritability after previous eczemaS.M. John, H.J. Schwanitz, University of Osnabrück (Osnabrück, D)

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PROGRAM

FRIDAY, MAY 23, 2003 Room 6

12:00 - 14:00

Lunchsymposium: GF-Messtechnik GmbH

Optical 3D in vivo skin measurement by PRIMOS-technology and applicationChair: G. Frankowski, Berlin, D

12:00 WelcomeG. Frankowski (Berlin, D)

12:05 Experiences in the application of the projected fringe method in cosmeticresearchS. Jaspers (Hamburg, D)

12:45 Experiences of the application of the PRIMOS in clinical applicationH.-P. Berlien, B. Algermissen (Berlin, D)

13:15 Computer aided 3D modelling of skin surfaces in vivo measured byPRIMOSN. Deichmann (Copenhagen, DK); M. Chen, (Berlin, D)

13:30 New fields of development and application of the PRIMOS technologyG. Frankowski (Berlin, D); D. Canfield (Fairfield, USA)

13:50 SummaryG. Frankowski (Berlin, D)

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PROGRAM

FRIDAY, MAY 23, 2003 Room 6

14:30 - 16:15

Plenary V

Poster ViewingChair: H.I. Maibach, San Francisco, USA; J. Serup, Linköping, S

14:30 Poster Viewing in the Poster Area

15:30 Moderated session including announcement of poster prizes in room 5

For full listing of posters to be presented please refer to page 27The poster authors must be present by their poster as follows:Even numbers: Friday 23 10:00 - 10:30 & 14:30 - 15:00Odd numbers: Friday 23 12:00 - 12:30 & 15:00 - 15:30

16:15 Coffee break and exhibition visit

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PROGRAM

FRIDAY, MAY 23, 2003 Room 6

16:45 - 18:05

Symposium 3 A

Epiluminescence microscopy & multimodal skin imagingChair: W. Stolz, Munich, D; H. Voigt, Hamburg, D

16:45 Basics of dermatoscopy 44W. Stolz, Krankenhaus Munich-Schwabing (Munich, D)

17:05 Substructure Cohesion Analysis (SCA) in borderline melanocytic 45lesionsH. Voigt, Melanoma Research Project (Hamburg, D)

17:20 Videocapillaroscopy allows assessment of scalp capillary loops 46increase due to a hair lotion containing VEGF stimulating agentA. Degouy1, J.M. Sainthillier2, A.M. Schmitt3, P. Creidi2, V. ErmosillaMichel4, P. Humbert11 CHU de Besançon (Besançon, F)2 Laboratory of Engineering and Cutaneous Biology (Besançon, F)3 Laboratoires Pierre Fabre (Lavaur, F)4 Laboratoires Pierre Fabre (Vigoulet Auzil, F)

17:35 A spectroscopic study of the borders of UV-induced skin erythema 47E. Häggblad, H. Petersson, M.A. Ilias, C. Anderson, E.G. Salerud,Linköpings University (Linköping, S)

17:50 Applications of ATR-IR spectroscopic imaging to skin 48S. Kazarian, A. Chan, Imperial College (London, UK)

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PROGRAM

FRIDAY, MAY 23, 2003 Room 5

16:45 - 18:05

Symposium 3 B

New bioengineering techniquesChair: G. Grove, Media, USA; S. Jaspers, Hamburg, D

16:45 News in itch measurements 49G. Yosipovitch, Wake Forest Medical Center (Winston Salem, USA)

17:05 Measurement of water evaporation rates with a closed chamber 50TEWL meterJ. Nuutinen1, E. Alanen1, T. Lahtinen21 Delfin Technologies Ltd (Kuopio, FIN)2 University of Kuopio (Kuopio, FIN)

17:20 Electrical impedance for evaluation of different skin tumours 51I. Nicander, U. Holmgren, P. Åberg, S. Ollmar, Huddinge UniversityHospital, Läkarmottagningen Hötorgscity, Karolinska Institutet(Huddinge, Stockholm, S)

17:35 EdemaMeter - a new device to detect tissue edema in skin and 52subcutaneous tissuesT. Lahtinen1, R. Ikäheimo2, E. Lampainen2, J. Nuutinen31 University of Kuopio (Kuopio, FIN)2 University Hospital of Kuopio (Kuopio, FIN)3 Delfin Technologies Ltd (Kuopio, FIN)

17:50 Skin surface pH fluctuates in function of skin sites, populations, 53age, season and daytimeS. Guehenneux, F. Morizot, J. Latreille, C. Guinot, E. Tschachler,C.E.R.I.E.S (Neuilly sur Seine, F)

20:00 Congress dinner at Zippelhaus(see page 48)

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PROGRAM

SATURDAY, MAY 24, 2003 Room 6

09:00 - 10:40

Plenary VI

MRI & skin surface imagingChair: J.-L. Lévèque, Clichy, F; A. Zemtsow, Muncie, USA

09:00 Optical analysis of skin surface - approach to the skin radiance 54P. Humbert, T. Gharbi, University Hospital St Jacques, University ofFranche-Comté (Besançon, F)

09:20 State of the art of magnetic resonance imaging of the skin 55B. Querleux, L’Oréal Recherche (Aulnay-sous-bois, F)

09:40 SAFIR - Skin Analysing Fluorescence Imaging Recorder: 56an extended fluorescent view into the human follicleA. Herpens1, S. Scheede1, S. Schagen1, B. Timmermann1,V. Schreiner1, H. Wenck1, K. Wittern1, A. Klose2, R. Kruse21 Beiersdorf AG (Hamburg, D)2 Otto-von-Guericke-Universität (Magdeburg, D)

09:55 Three-dimensional imaging representations. A method to 57visualize subtle changes of the human cutaneous structuresM.D. Vazquez-Duchêne, V. Gillon, J.L. Contet-Audonneau, O. Freis,G. Perié, C. Jeanmaire, D. Gauché, G. Pauly, LaboratoiresSerobiologiques Division de Cognis (Pulnoy, F)

10:10 Signal versus noise: the interest of new methods for hair growth - 58hair loss monitoring in human skin in vivoD.J.J. Van Neste, Skinterface (Tournai, B)

10:25 Directions for in vivo fibre optic confocal microscopy 59P. Delaney, R. Pattie, S. Thomas, Optiscan Pty Ltd (Notting Hill, AUS)

26

PROGRAM

SATURDAY, MAY 24, 2003 Room 6

11:15 - 12:45

Plenary VII

Ultrasound & functional imagingChair: J. C. Bamber, Sutton, UK; M. Stücker, Bochum, D

11:15 Multimodal imaging - what can we expect? 60H. Ermert, Ruhr-University (Bochum, D)

11:35 Sonographic reflex-transmission imaging and co-registered optical 61surface feature analysisJ.C. Bamber1, N.L. Bush1, M. Dickson1, C. Guittet1, Z. She2, P. Fish2,D. Rallen3, C.C. Harland3, P.S. Mortimer11 Institute of Cancer Research (Sutton, UK)2 University of Wales (Bangor, UK)3 Sutton Hospital (Sutton, UK)

11:55 Visualisation of skin oxygenation 62M. Stücker, Ruhr-University Bochum (Bochum, D)

12:15 Automatic measurement of dermal thickness from B-scan 63ultrasound images using active contoursJ.-M. Lagarde, J. George, R. Soulcié, D. Black, S. Diridollou,Institut de Recherche Pierre Fabre (Toulouse, F)

12:30 Sensitive skin objectivation by functional MRI 64B. Querleux1, R. Jourdain2, K. Dauchot3, Y. Burnod4, J. Bittoun2,P. Bastien2, O. de Lacharrière11 L’Oréal Recherche (Aulnay-sous-bois, F)2 L’Oréal Recherche (Clichy, F)3 INSERM U483, Université Paris VII (Paris, F)4 CIERM - CNRS ESA 8081 (Le Kremlin-Bicêtre, F)

12:45 Closing CeremonyChair: S. El Gammal, Freudenberg, D; P. Elsner, Jena, D;K.-P. Wilhelm, Hamburg, D

27

POSTERS

The poster authors must be present by their poster as follows:Even numbers: Friday 23, 10:00 - 10:30 & 14:30 - 15:00Odd numbers: Friday 23, 12:00 - 12:30 & 15:00 - 15:30

P65 Investigation of the phase behavior of the different alpha and betahydroxycarboxylic acidsA. Al-Bawab, University of Jordan (Amman, JOR)

P66 Classification of fluorescence images of skin lesions based on PCA andlocal ICAH.G. Stockmeier, C. Bauer, F. Theis, W. Bäumler, C. Abels, E.W. Lang,University of Regensburg (Regensburg, D)

P67 Neural representations in videomicroscopyJ.-M. Sainthillier, P. Humbert, T. Gharbi, LIBC, Laboratoire d’Optique PMDuffieux (Besançon, F)

P68 Automatic nevus counting: a pilot studyT.K. Lee, M. King, S. Lau, M.S. Atkins, D.I. McLean, BC Cancer Agency,Simon Fraser University, Vancouver Hospital and Health Sciences Centre(Vancouver, Burnaby, CAN)

P69 Pilosebaceal unit. Histometry and 3D featuresZ. Milosavljevic, S. Jancic, G. Samardzic, University Medical School(Kragujevac, YU)

P70 Non- and semi-invasive quantitative and qualitative assessment ofepidermal regeneration by the use of an in vivo wound healing modelD. Haentschel, M. Gorath, J. Degwert, SIT Skin Investigation andTechnology Hamburg GmbH (Hamburg, D)

P71 Two-dimensional modeling of the mechanical properties of human skinT. Heinrich, University of the German Armed Forces (Hamburg, D)

P72 The skin electrophysiological imaging (SEI): methodological and phenom-enological findingsY. Babich, Institute for Applied Problems of Physics & Biophysics(Kiev, UKR)

P73 Skin microrelief topography measurements of ageing skin using a lighttransmission methodK. De Paepe, J.-P. Hachem, E. Houben, J.-M. Lagarde, Y. Galle, D. Roseeuw,V. Rogiers, Vrije Universiteit Brussel, Academic Hospital-Jette, Pierre FabreResearch Institute (Brussels, B; Toulouse, F)

P74 Quantifying skin ashing using cross-polarized imagingH. Santanastasio, S. Zhang, S. Krishnan, R. Velthuizen, P. Shah, L. Tsaur,Unilever Research US (Edgewater, USA)

28

POSTERS

P75 Changes in mechanical properties of the skin caused by photoagingA. Oba, POLA Chemical Industries Inc. (Yokohama, JP)

P76 A mechanical model for the skin suction experimentD. Brokken, L.J.M. Schlangen, P.M. van Kemenade, Philips ResearchLaboratories (Eindhoven, NL)

P77 Hair cycle transitions: in vivo monitoring using contrast enhanced photo-trichogramD.J.J. Van Neste, Y. Demortier, Skinterface (Tournai, B)

P78 Blue light visualizes the degree of solar elastosis in photodamagedhuman facial skinI. Sadiq, T. Stoudemayer, A. Kligman, S.K.I.N., Incorporated(Conshohocken, USA)

P79 Use of trans-cutaneous oxygen and carbon dioxide monitoring to assessthe breathability of the skin and skin formulationsL. Ilardi, V. Foy, C. Penksa, I. Flores, S. Burke, Unilever Research andDevelopment (Edgewater, USA)

P80 In vivo study of skin mechanical properties in Raynaud’s phenomenonH. Dobrev, Medical University (Plovdiv, BG)

P81 Objective evaluation of severity in SLS-induced irritant dermatitis:comparing the studies between new skin color analysis technique andother bioengineering toolsH.-C. Kim, S.-J. Hong, M.-H. Lee, J.-S. Moon, H.-S. Oh, M.-G. Kim,C.-H. Oh, S.-Y. Park, Korea University (Seoul, KOR)

P82 Objective evaluation for lesional severity in atopic dermatitisH.-S. Oh, S.-W Son, Y.-M. Yoon, S.-Y. Park, H.-C. Kim, J.-S. Moon,M.-G. Kim, C.-H. Kim, Korea University (Seoul, KOR)

P83 Human hair follicle organ culture as a screening tool for „hair drug’’discoveryA. Zambon Bertoja, A. Mescalchin, P. Pertile, R. Paus, Cutech Srl,University of Hamburg (Padua, I; Hamburg, D)

P84 Real time spatial compound imaging versus conventional high frequencyultrasonography of normal and psoriatic nailsE.A. Holm, X. Wortsman, M. Gniadecka, H.C. Wulf, G.B.E. Jemec,Division of Dermatology, Imaging Department (Roskilde, DK; Santiago, CL;Copenhagen, DK)

29

POSTERS

P85 The effect of urea from dermo-cosmetic emulsions on skin hydration andits barrier function: a vehicle-controlled studyS. Savic, N. Cekic, S. Tamburic, J. Milic, G. Vuleta, Belgrade Faculty ofPharmacy, DCP Hemigal, The London Institute (Belgrade, Leskovac, YU;London, UK)

P86 Measurement of skin hydration in the diapered area of infants with aclosed chamber TEWL meterE. Alanen, F. Wiesemann, J. Nuutinen, T. Lahtinen, Delfin TechnologiesLtd, Procter & Gamble, University of Kuopio (Kuopio, FIN; Schwalbach, D)

P87 In-vivo determination of mechanical properties of human dermis, using anumerical-experimental techniqueF.M. Hendriks, D. Brokken, J.T.W.M. van Eemeren, C.W.J. Oomens,F.P.T. Baaijens, Eindhoven University of Technology, Philips ResearchLaboratories (Eindhoven, NL)

P88 Comparisons of skin characteristics between men and women usingnon-invasive methods in young healthy AsiansH.K. Lee, S.Y. Ahn, J.H. Bae, S.J. Moon, I.S. Chang,Amore Pacific R&D Center (Yongin, KOR)

P89 Skin mapping using a low-cost digital imaging systemJ. Smolle, G. Paar, A. Gerger, University of Graz, Joanneum Research(Graz, A)

P90 Bioengineered characterization of the thermal burn injury healing processL. Monteiro Rodrigues, J. Martins Magro, M. Mouzinho, P. Pinto,M. Almeida, University of Lisbon , Hospital S. José (Lisbon, P)

P91 The plastic occlusion stress test as a tool to assess damage inflicted tothe skin barrier functionC. Rosado, P.C. Pinto, L. Monteiro Rodrigues, University of Lisbon,UDE-ULHT (Lisbon, P)

P92 Pressure-controlled measurement of skin surface hydration withMoistureMeterJ. Nuutinen, E. Alanen, K. Nicklen, Delfin Technologies Ltd (Kuopio, FIN)

P93 Free radical scavenging effectiveness of dermally applied ascorbylpalmitateM. Gasperlin, P. Jurkovic, M. Sentjurc, J. Kristl, University of Ljubljana,J. Stefan Institute (Ljubljana, SLO)

P94 Improvement of dermal extracellular matrix structure and compositionafter treatment with Imedeen Time Perfection in an in vitro skin equivalentC. Bouez, O. Damour, J. Vicanova, Banque de Tissus et Cellules HLC,Ferrosan A/S (Lyon, F; Soeborg, DK)

30

POSTERS

P95 Visioscan VC 98 application: a comparison study between coarse andsmooth skin surfaceR. Pena Ferreira, P. Costa, F. Bahia, FFUP (Porto, P)

P96 Moisturizing properties of two oleogels following single applicationI.F. Almeida, D. Endo, M.F. Bahia, Faculty of Pharmacy, State University(Porto, P; Maringá, BR)

P97 Percutaneous penetration of diclofenac: comparison between the in vivoiontophoretic delivery and passive diffusionR. Lambrecht, P. Clarys, A.O Barel, Vrije Universiteit Brussel (Brussels, B)

P98 Skin microtopography: age-related changes in Caucasian and JapanesewomenS. Guehenneux, I. Le Fur, H. Zahouani, R. Vargiolu, L. Ambroisine,C. Guinot, E. Tschachler, C.E.R.I.E.S., Ecole Centrale de Lyon (Neuilly surSeine, Lyon, F)

P99 Short-term glucocorticoid treatment compromises both permeabilitybarrier homeostasis and stratum corneum integrity: inhibition of epider-mal lipid synthesis accounts for functional abnormalitiesJ.W. Fluhr, J.S. Kao, P.M. Elias, K.R. Feingold, Skin Physiology Laboratory,UCSF (Jena, D; San Francisco, USA)

P100 Improvement of penetration of a topical corticoid by waterfiltered infra-red A (wIRA)L. Bankova, C. Heinemann, J.W. Fluhr, G. Hoffmann, P. Elsner,Friedrich-Schiller-University, Johann-Wolfgang-v.-Goethe University(Jena, Frankfurt, D)

P101 Capacitance measurement of skin moisture: sophisticated calibrationof instrumentsS. Bielfeldt, M. Brandt, A. Gerstenkorn, K.-P. Wilhelm, proDERM(Schenefeld, D)

P102 Validation of improved texture and elasticity measures using benchmarkcosmetic and dermatological anti-aging treatmentsS.S. Hawkins, C. Feinberg, M. Matzke, U. Santhanam, R.L. Weinkauf,Unilever R&D (Edgewater, USA)

P103 Measuring technique of the facial pore size and its evaluation in KoreanwomenS. Park, S.-J. Kim, Y. Yoo, S. Kang, LG Household & Health Care, ChonnamNational University Medical School (Taejeon, Kwangju, KOR)

31

POSTERS

P104 Detection of oxidative processes and the effectiveness of antioxidants(vitamin C) in/on the skin using UVA-induced UPE measurementtechniquesF. Khabiri, W. Mei, R. Hagens, V. Schreiner, H. Wenck, K.-P. Wittern,H.-J. Duchstein, Beiersdorf AG, University of Hamburg (Hamburg, D)

P105 A rapid, accurate, and facile method to quantify the antioxidative capacityof topical formulationsH. Zhai, M.J. Choi, M. Arens-Corell, B.A. Neudecker, H.I. Maibach,University of California, Sebapharma GmbH & Co(San Francisco, USA; Boppard, D)

P106 Visibility of facial wrinkle reduction as assessed by various types ofobserversJ.H.D.M. Westerink, Personal Care Institute, Philips Research(Eindhoven, NL)

P107 Versatility of the skin sorption-desorption test in assessing personalcare productsP.Y. Kazmi, G.L. Grove, B.M. Morrison, Jr, Colgate-Palmolive Co., KGL’sSkin Study Center (Piscataway, USA)

P108 Combination of textile and cosmetic sun protectionH. Tronnier, B. Hölzner, U. Heinrich, DermaTronnier (Witten, D)

P109 Validation of a compartmental model to quantitatively describe trans-epidermal water lossP. C. Pinto, R. Minhós, L. M. Pereira, L. Monteiro Rodrigues, UDE-ULHT,University of Lisbon (Lisbon, P)

P110 Skin water dynamics: disposition-decomposition analysis (DDA) of trans-epidermal water loss (TEWL) and epidermal capacitanceP. C. Pinto, L. M.Pereira, L. Monteiro Rodrigues, UDE-ULHT, University ofLisbon (Lisbon, P)

P111 Assessment of irritant skin reactions using electrical impedance -a comparison between two laboratoriesN. Kuzmina, C. Duval, S. Johnsson, A. Boman, L. Emtestam, M. Lindberg,Karolinska Institutet (Stockholm, S)

P112 Principles and practices for the DermaLab suction cupG. Grove, J. Damia, E. Pierce, C. Zerweck, cyberDERM, inc., Skin StudyCenter (Media, Broomall, USA)

P113 Experimental models for testing the efficacy and bioequivalence of lowdose dermatocorticoidsW. Wigger-Alberti, D. Wilhelm, S. Bielfeldt, K.-P. Wilhelm, proDERM(Schenefeld, D)

32

POSTERS

P114 Site variations in susceptibility to SLS at the volar forearm evaluated byTEWL measurementM. Bock, H.J. Schwanitz, University of Osnabruck (Osnabruck, D)

P115 A comparative study on the skin penetration of pure Tryptanthrin andTryptanthrin in Isatis tinctoria extract by subcutaneous microdialysiscoupled with isotope dilution ESI-LC-MSC. Heinemann, C. Oberthür, E. Benfeldt, M. Hamburger, P. Elsner, Friedrich-Schiller-University, University of Copenhagen (Jena, D; Copenhagen, DK)

P116 Melanoma biology in human skin reconstructsC. Berking, K. Hoelzle, M. Herlyn, Ludwig-Maximilians-University ofMunich, The Wistar Institute (Munich, D; Philadelphia, USA)

P117 Is it possible to define a „biological age’’ of the skin?M. Setaro, A. Sparavigna, DermIng (Monza, I)

P118 New skin colour analysis techniqueH.-S. Oh, M.-H. Lee, S.-Y. Park, H.-C. Kim, J.-S. Moon, M.-G. Kim,C.-H. Oh, Korea University (Seoul, KOR)

P119 Experiences with in vitro evaluation of sun care productsH. Tronnier, D. Kockott, U. Heinrich, DermaTronnier (Witten, D)

P120 Frictiometry on human skinH. Tronnier, M. Wiebusch, U. Heinrich, DermaTronnier (Witten, D)

P121 Is skin sensitivity predictable by bioengineering methods?N. Kuzmina, L. Hagströmer, M. Nyrén, L. Emtestam, Karolinska Institute(Stockholm, S)

P122 Fringes projection for the study of the morphological modification of eye-bags under the effect of a treatmentJ.C. Pittet, P. Beau, Spincontrol (Tours, F)

P123 A new in vivo screening method for UV-B and UV-A protection avoidingerythemal skin reactionsS. Bielfeldt, K. Wilhelm, proDERM Institute for Applied Dermatol. Research(Schenefeld, D)

P124 Opto-thermal hydration measurements for in-vitro stratum corneumsamplesP. Xiao, X. Guo, R.E. Imhof, South Bank University, University of Toronto(London, UK; Toronto, CAN)

P125 Opto-thermal in-vivo skin depth profiling using neural network methodsY. Cui, P. Xiao, R.E. Imhof, C. Glorieux, South Bank University, KatholiekeUniversiteit (London, UK; Leuven, B)

33

POSTERS

P126 New method for measuring water desorption rates of in-vitrobiomaterialsL.I. Ciortea, E.P. Berg, P. Xiao, R.E. Imhof, South Bank University, BioxSystems Ltd (London, UK)

P127 Dermatoscopic images investigated with morphometric measurementsby tissue counter analysisA. Gerger, W. Stolz, R. Pompl, J. Smolle, University of Graz,University of Regensburg, Max-Planck Institute for Extraterrestrial Physics(Graz, A; Regensburg, Garching, D)

P128 Dermoscopic features of nevus-associated melanomaM. Stante, P. Carli, D. Massi, V. De Giorgi, University of Florence(Florence, I)

P129 Evaluation of skin surface structure after UV-exposures using opticalprofilometryA. Orlikov, T. Gambichler, R. Vasa, M. Stücker, P. Altmeyer, K. Hoffmann,Ruhr-University Bochum (Bochum, D)

P130 Arterial audiophotoplethysmography (aPPG) is a simple and reliablemethod to measure digital blood pressureS. El Gammal, B. Lambotte, C. El Gammal, V. Blazek, KrankenhausBethesda, Institut für Hochfrequenztechnik, Technical Universität(Freudenberg, Aachen, D)

P131 Three dimensional ultrasound imaging for the study of the dermis/hypodermis interfaceJ.C. Pittet, P. Beau, Spincontrol (Tours, F)

P132 Assessment of epidermal modifications after repeated ultraviolet A and Birradiation by optical coherence tomography (OCT): preliminary resultsR. Vasa, T. Gambichler, A. Orlikov, P. Altmeyer, M. Stücker, K. Hoffmann,Ruhr-University Bochum (Bochum, D)

P133 Assessment of identical morphologic structures investigated with stand-ard histology and optical coherence tomographyA. Orlikov, T. Gambichler, R. Vasa, M. Stücker, P. Altmeyer, K. Hoffmann,Ruhr-University Bochum (Bochum, D)

P134 Optical coherence tomography of wound healingU. Rades, Y. Gaber, J. Welzel, University of Lübeck (Lübeck, D)

P135 Measurement of the epidermal thickness using optical coherencetomographyM. Cossmann, C. Reinhardt, J. Welzel, University of Lübeck (Lübeck, D)

34

POSTERS

P136 OCT measurement of epidermal thickness. Regional differences and thechange with aging of Japanese womenT. Tsugita, T. Nishijima, T. Kitahara, Y. Takema, Kao Corporation(Ichikai-Machi, Haga-Gun, JP)

P137 Monitoring product induced changes in skin hydration by near-infraredreflectance spectroscopy and multispectral imagingS.L. Zhang, C.L. Meyers, D. Palatini, T. Hancewicz, K. Subramanyan, B. VanBlarcom, S.S. Hawkins, P. Kaplan, Unilever Research and Development(Edgewater, USA)

P138 Non-invasive analysis of the internal structure of human pores in the skinusing in-vivo confocal microscopyT. Kitahara, K. Sugata, T. Nishijima, Y. Takema, Kao Corporation(Haga Tochigi, JP)

P139 Comparison of two different suction cup methods - a methodologicalstudyL. Pedersen, B. Hansen, G.B.E Jemec, Division of Dermatology,Osteoporosis Reserach Laboratorium (Roskilde, Hvidovre, DK)

35

Abels, C. ............................................ P66Åberg, P. .............................................. 51Ahn, S.Y. ............................................ P88Akasaki, S. ........................................... 32Alanen, E. ............................ 50, P86, P92Al-Bawab, A. ..................................... P65Almeida, I.F. ...................................... P96Almeida, M........................................ P90Altmeyer, P. ............ 6, P129, P132, P133Ambroisine, L. .................................. P98Anderson, C. ....................................... 47Anikijenko, P. ......................................... 7Arens-Corell, M. .............................. P105Atkins, M.S. ....................................... P68Baaijens, F.P.T. ............................. 16, P87Babich, Y. ........................................... P72Bae, J.H. ............................................ P88Bahia, M.F. ................................. P95, P96Baldeweck, T. ...................................... 23Bamber, J.C. ........................................ 61Bankova, L. ................................ 10, P100Barel, A. ....................................... 22, P97Bastien, P. ............................................ 64Bauer, C. ............................................ P66Bäumler, W........................................ P66Beau, P. ..................................P122, P131Benfeldt, E. ................................ 26, P115Berg, E.P. ......................................... P126Berking, C. ....................................... P116Bielfeldt, S. ................. P101, P113, P123Binder, M. ............................................ 18Bittoun, J. ............................................ 64Black, D. ............................................... 63Blazek, V. ......................................... P130Bock, M............................................ P114Boman, A. ....................................... P111Bonev, S. ............................................... 2Bouez, C. ........................................... P94Brandt, M. ....................................... P101Braue, Jr., E.H. .................................... 41Bray, R.C. ............................................. 14Brokken, D. .......................... 16, P76, P87Burke, S. ............................................ P79

Burnod, Y. ............................................ 64Bush, N.L. ............................................ 61C. Pinto, P. .............................P109, P110Carli, P. ............................................. P128Catheline, S. ........................................ 23Cekic, N. ............................................ P85Chan, A. ............................................... 48Chang, I.S. ......................................... P88Choi, M.J. ........................................ P105Ciortea, L.I. ...................................... P126Clarys, P. ...................................... 22, P97Contet-Audonneau, J.L. ..................... 57Cornillon, C. ........................................ 23Cossmann, M. ................................. P135Costa, P. ............................................. P95C.Pinto, P. .......................................... P91Creidi, P. ............................................... 46Cui, Y. ............................................... P125Damia, J. ......................................... P112Damour, O. ........................................ P94Dauchot, K. .......................................... 64De Giorgi, V. .................................... P128de Lacharrière, O. ............................... 64De Paepe, K. ...................................... P73Decaillet, F. .......................................... 28Degouy, A. ........................................... 46Degwert, J. ........................................ P70Delaney, P. ....................................... 7, 59Demortier, Y. ..................................... P77Dickson, M. ......................................... 61Diridollou, S. ....................................... 63Dobrev, H. ......................................... P80Drexler, H. ........................................... 27Dubben, H.-H. ....................................... 1Duchstein, H.-J. .............................. P104Duval, C. .......................................... P111Dykes, P. .............................................. 31Egawa, M. ..................................... 11, 19El Gammal, C. ................................. P130El Gammal, S. ............................. 4, P130Elias, P.M. .................................... 10, P99Elsner, P. .............. 25, 39, 42, P100, P115Emtestam, L. ......................... P111, P121

INDEX OF AUTHORS

36

Endo, D. ............................................. P96Ermert, H. .................................... 4, 5, 60Ermosilla Michel, V. ............................ 46Feinberg, C. ..................................... P102Feingold, K.R. .............................. 10, P99Fink, M. ................................................ 23Fish, P. .................................................. 61Flament, F. ........................................... 20Fleming, M. ......................................... 24Flores, I. ............................................. P79Fluhr, J.W. ................... 10, 42, P99, P100Forrester, K.R. ..................................... 14Foy, V. ................................................ P79Freeman, M. ........................................ 17Freis, O. ............................................... 57Fuchs, S.M. ......................................... 42Fujimura, T. ......................................... 32Fukuhara, T. ........................................ 11Gaber, Y. .......................................... P134Galle, Y. ............................................. P73Gambichler, T. ............ P129, P132, P133Gasperlin, M. .................................... P93Gauché, D. ........................................... 57Génisson, J.L. ..................................... 23George, J. ............................................ 63Gerger, A. .................... 37, 38, P89, P127Gerstenkorn, A. ............................... P101Gharbi, T. ..................................... 54, P67Gillon, V. ........................................ 21, 57Glorieux, C. ..................................... P125Gniadecka, M. ................................... P84Göen, T. ............................................... 27Gollnick, H. ............................................ 9Gonzalez, S. ........................................ 13Gorath, M. ......................................... P70Gräfe, U. .............................................. 42Grove, G.L. ............................P107, P112Guehenneux, S. .................... 18, 53, P98Guillod, J. ............................................ 28Guinot, C. ........................ 18, 53, P98, 61Guo, X. ............................................ P124Hachem, J.-P. .................................... P73Haentschel, D. ................................... P70

Hagens, R. ....................................... P104Häggblad, E. ........................................ 47Hagströmer, L. ................................ P121Hamburger, M. ................................ P115Hancewicz, T. .................................. P137Hansen, B. ....................................... P139Harland, C.C. ....................................... 61Hawkins, S.S. ........................ P102, P137Heinemann, C. ................ 42, P100, P115Heinrich, T. ........................................ P71Heinrich, U. ................ P108, P119, P120Hendriks, F.M. ............................. 16, P87Herlyn, M. ........................................ P116Herpens, A. ......................................... 56Hirao, T. ......................................... 11, 19Hoelzle, K. ....................................... P116Hoffmann, G. .................................. P100Hoffmann, K. .... 5, 34, P129, P132, P133Holm, E.A. ......................................... P84Holmgren, U. ...................................... 51Hölzner, B. ....................................... P108Hong, S.-J. ........................................ P81Höpfner, A. ............................................ 2Hori, K. ................................................. 32Houben, E. ......................................... P73Houben, M.M.J. .................................. 12Humbert, P. ...................... 20, 46, 54, P67Ikäheimo, R. ........................................ 52Ilardi, L. .............................................. P79Ilias, M.A. ............................................ 47Imhof, R.E. .................. P124, P125, P126Jancic, S. ........................................... P69Jeanmaire, C. ...................................... 57Jemec, G.B.E...........................P84, P139John, S.M. ........................................... 43Johnsson, S. ................................... P111Jones, B. .............................................. 17Jourdain, R. ......................................... 64Jurkovic, P. ........................................ P93Kang, S. ........................................... P103Kao, J.S. ............................................ P99Kaplan, P. ......................................... P137Kaspar, K. .............................................. 4

INDEX OF AUTHORS

37

Kazarian, S. ......................................... 48Kazmi, P.Y. ....................................... P107Khabiri, F. ........................................ P104Kim, C.-H. .......................................... P82Kim, H.-C. ................. 36, P81, P82, P118Kim, M.-G. ................ 36, P81, P82, P118Kim, S.-J. ......................................... P103King, M. ............................................. P68Kitahara, T. ............................ P136, P138Kligman, A. ....................................... P78Klose, A. .............................................. 56Knüttel, A. ............................................. 2Kockott, D. ....................................... P119König, K. .............................................. 15Korinth, G. ........................................... 27Korthagen, E.J.M ................................ 16Krishnan, S. ....................................... P74Kristl, J. ............................................. P93Kruse, R. .............................................. 56Kunt, M. ............................................... 28Kuzmina, N. ........................... P111, P121Lagarde, J.-M. ............................. 63, P73Lahtinen, T. ........................... 50, 52, P86Lambotte, B. .................................... P130Lambrecht, R. .............................. 22, P97Lampainen, E. ..................................... 52Lang, E.W. ......................................... P66Latreille, J. ........................................... 53Lau, S. ................................................ P68Le Fur, I. ............................................. P98Lee, H.K. ............................................ P88Lee, M.-H. ................................P81, P118Lee, T.K. ............................................. P68Leonard, C. .......................................... 14Lindberg, M. .................................... P111Lucassen, G.W. ..................................... 6M. Pereira, L. ................................... P109Maibach, H.I. ............................. 29, P105Marks, R. ............................................. 31Martins Magro, J. ............................. P90Massi, D. .......................................... P128Matzke, M. ....................................... P102Mauger, E. ........................................... 18

Mavon, A. ............................................ 20McLean, D.I. ...................................... P68Mei, W. ............................................ P104Mescalchin, A. .................................. P83Metzner, U. .......................................... 25Meyers, C.L. .................................... P137Milic, J. .............................................. P85Milosavljevic, Z. ................................ P69Minhós, R. ....................................... P109Monteiro Rodrigues, L. ............ P90, P91...............................................P109, P110Moon, J.-S. ............... 36, P81, P82, P118Moon, S.J. ......................................... P88Moriwaki, S. ........................................ 32Morizot, F. ...................................... 18, 53Morrison, Jr, B.M. ........................... P107Mortimer, P.S. ..................................... 61Mouzinho, M. .................................... P90M.Pereira, L. .................................... P110Murr, E. .................................................. 7Naldi, L. ............................................... 40Neerken, S. ............................................ 6Neudecker, B.A. .............................. P105Nicander, I. .......................................... 51Nicklen, K. ......................................... P92Nishijima, T. ..........................P136, P138Nuijs, A.M. ............................................ 6Nuutinen, J. .................. 50, 52, P86, P92Nyrén, M. ........................................ P121Oba, A. ............................................... P75Oberthür, C. ..................................... P115Oh, C.-H. ............................ 36, P81, P118Oh, H.-S. ................... 36, P81, P82, P118Ollmar, S. ............................................ 51Oomens, C.W.J. .......................... 16, P87Orlikov, A. ................... P129, P132, P133Osanai, O. ............................................ 32Ozaki, Y. ............................................... 11Paar, G. .............................................. P89Pailler, C. ............................................. 33Palatini, D. ....................................... P137Panizzon, R. ......................................... 28Park, S.G. ......................................... P103

INDEX OF AUTHORS

38

Park, S.-Y. ................. 36, P81, P82, P118Pattie, R. .............................................. 59Pauly, G. ........................................ 21, 57Paus, R. .............................................. P83Pedersen, L. .................................... P139Pehamberger, H. ................................. 35Pena Ferreira, R. ............................... P95Penksa, C. .......................................... P79Perié, G. ......................................... 21, 57Pertile, P. ............................................ P83Petersson, H. ....................................... 47Pierard, G. ............................................. 8Pierce, E. .......................................... P112Pinto, P. .............................................. P90Pittet, J.C. ..............................P122, P131Pompl, R. ......................................... P127Präßler, J. ............................................ 25Querleux, B. ............................ 23, 55, 64Rades, U. ......................................... P134Rallen, D. ............................................. 61Reese, A. ............................................... 7Reinhardt, C. ................................... P135Rogiers, V. ......................................... P73Rosado, C. ......................................... P91Roseeuw, D. ...................................... P73Sadiq, I. ............................................. P78Sainthillier, J.-M. ........................ 46, P67Salerud, E.G. ....................................... 47Samardzic, G. .................................... P69Santanastasio, H. .............................. P74Santhanam, U. ................................ P102Savic, S. ............................................. P85Schagen, S. ......................................... 56Schaller, K.H. ....................................... 27Scharenberg, R. .................................... 5Scharenberg, S. .................................... 5Scheede, S. ......................................... 56Schlangen, L.J.M. ............................. P76Schliemann-Willers, S. ....................... 42Schmid-Saugeon, . ............................. 28Schmitt, A.M. ...................................... 46Schreiner, V. .............................. 56, P104Schuurman, A.M. ............................... 16

Schwanitz, H.J. ......................... 43, P114Seipel, W. ............................................ 21Sentjurc, M........................................ P93Setaro, M. ........................................ P117Shah, P. .............................................. P74She, Z. ................................................. 61Smolle, J. .................... 37, 38, P89, P127Son, S.-W .......................................... P82Soulcié, R. ........................................... 63Sparavigna, A. ................................ P117Stante, M. ........................................ P128Stewart, C. ........................................... 14Stockmeier, H.G. ............................... P66Stolz, W. .................................... 44, P127Stoudemayer, T. ................................ P78Stücker, M. ........... 62, P129, P132, P133Subramanyan, K. ............................ P137Sugata, K. ........................................ P138Swindle, L. .......................................... 17Takahashi, M. ................................ 11, 19Takema, Y. ....................... 32, P136, P138Tamburic, S. ...................................... P85Tanter, M. ............................................ 23Theis, F. ............................................. P66Thielitz, A. ............................................. 9Thiran, J.P. ........................................... 28Thomas, S. ................................ 7, 17, 59Timmermann, B. ................................. 56Tittelbach, J. ........................................ 25Tronnier, H. ................. P108, P119, P120Tsaur, L. ............................................. P74Tschachler, E. ........................ 18, 53, P98Tsugita, T. .................................. 32, P136Tulip, J. ................................................ 14Van Blarcom, B. .............................. P137van Eemeren, T.W.M. ....................... P87van Kemenade, M. ........................... P76Van Neste, D.J.J. ........................ 58, P77Vankemenade, M. ............................... 12Vargiolu, R. ............................ 20, 33, P98Vasa, R. ....................... P129, P132, P133Vazquez-Duchêne, M.D. ..................... 57Velthuizen, R. .................................... P74

INDEX OF AUTHORS

39

Vicanova, J. ....................................... P94Vogt, M. ............................................. 4, 5Voigt, H. ............................................... 45Vuleta, G. ........................................... P85Weinkauf, R.L. ................................. P102Welzel, J. ........................... 3, P134, P135Wenck, H. .................................. 56, P104Westerink, H.D.M. ........................... P106Wiebusch, M. .................................. P120Wiesemann, F. .................................. P86Wigger-Alberti, W. .......................... P113Wilhelm, D. ..................................... P113Wilhelm, K.-P. ....... 30, P101, P123, P113Wiltgen, M........................................... 37

INDEX OF AUTHORS

Winter, C. ............................................... 3Wittern, K.-P. ............................. 56, P104Wortsman, X. .................................... P84Wulf, H. C. ......................................... P84Xiao, P. ........................ P124, P125, P126Yoo, Y. .............................................. P103Yoon, Y.-M. .................................. 36, P82Yosipovitch, G. .................................... 49Zahouani, H. .......................... 20, 33, P98Zambon Bertoja, . ............................. P83Zerweck, C. ...................................... P112Zhai, H. ............................................ P105Zhang, S. ................................. P74, P137

40

GENERAL INFORMATION

Registration Hours (on-site)

Wednesday, May 21, 2003 12.00-19.00Thursday, May 22, 2003 08.00-18.00Friday, May 23, 2003 08.00-18.00Saturday, May 24, 2003 08.30-13.00

Registration Deadlines

March 31, 2003 (reduced fee - Deadline 2)

Of course you can still register after March 31, 2003 including on-site registration at the meeting. Save time and money: Register inadvance!

Registration fees

Registration and payment receivedas from January 16, 03 as from April 1, 03to March 31, 03

ISBS/ISSI Members7 400.00 7 450.00

Non Members7 450.00 7 500.00

Scientists in training*; Students*Retirees* 7 230.00 7 280.00

Dayticket7 225.00 7 250.00

DayticketScientists in training*; Students*Retirees* 7 120.00 7 140.00

Congress Dinner**7 60.00 7 60.00

Congress Dinner**Scientists in training*; Students*Retirees* 7 40.00 7 40.00* Copy of official document required** Number of available Seats is limited

41

Included in the registration fee:

• Congress Bag• Final Program• Abstract Book (Copy of Skin Research and Technology Journal)• Admission to all Scientific Sessions of the Congress/ Satellite Symposium/Lunch Symposium• Opening Ceremony and Opening Lecture• Get-together• Coffee-Break

Registration for other educational parts of the congress and social events has tobe made and paid for separately (see registration form).

You also may wish to register via internet using the homepage:www.akm.ch/ISBS/ISSI2003

Payment

Add the registration and social program fees on the registration form todetermine the entire amount of payment due. Please pay this amount by creditcard, bank transfer or check payable in Euro funds. If using a credit card, indicatethe card type (Visa, Mastercard, American Express) entire card number (checkdigits), expiration date, and the cardholder’s signature. We recommend to effectremittance from other countries by credit card because of the bank and checkcharges. Expenses will be recharged as per actual costs.

If you are remitting fees by bank transfer, ensure that the full amount due in Eurofunds, is remitted free of charge to:

Deutsche Bank, Weil am Rhein, Germany,Account No 275 99 59.05 (BLZ 683 700 24).(Swift Code: Deut De 6F 679)

Be sure to instruct the financial institute to include the registrant’s name andaddress on the document.

Do not send registration forms or checks to any other address than to AKMCongress Service GmbH. Your registration will not be processed without payment.

Confirmation

Upon receipt of the full registration fee, each participant will receive a confirma-tion of registration and payment. Please present this confirmation at the registra-tion desk as proof of your advance registration.

GENERAL INFORMATION

42

Cancellation/Refund Policy

If you must cancel your registration and tickets, your written request must bereceived by April 10, 2003, at the Administrative Secretariat c/o AKM CongressService GmbH, in Weil am Rhein/Germany, to receive a refund, less 25% adminis-trative charge. After April 10, 2003, no refund can be made for cancellations.Vouchers for the official dinner cannot be replaced if lost. For any name changes,a fee of 7 15.00 will be charged.

The participant acknowledges that she/he has no rights to lodge damage claimsagainst the organisers should the holding of the Congress be hindered or prevent-ed by unexpected political or economic events or generally by force majeure, orshould non-appearance of speakers or other reasons necessitate programchanges. With her/his registration, the participant accepts this proviso.

Certification

The congress has been given certification by the German Dermatological Acade-my (DDA). For each 1/2 day attended you receive 3 advanced training pointswithin category A and for each full day, 6 advanced training points within categoryA. Please make sure you bring your membership card and have your detailsregistered at the congress secretariat each day.

Documentation

Advance registrants may pick up their registration packets (congress wallet,personal name badge, vouchers, final program, abstract booklet) at theregistration desk in the CCH Congress Centrum Hamburg.

Hotel reservation

Hotel rooms of various categories are preliminarily booked for the participants.Please send the enclosed hotel reservation form (page 21) to:

Hamburg Messe und Congress GmbHP.O. Box 302 48020308 Hamburg - GermanyFax: ++49 (0) 40 - 3569-2269

May is a very popular time for tourists as well as for other conventions.Please make your reservation early in advance!

Visa

The organizers recommend all participants to check the Visa-Agreement ofGermany with the respective country of origin. Participants may wish to contactthe German embassy of their country.

GENERAL INFORMATION

43

GENERAL INFORMATION

Coffee Break

Coffee service will be provided free of charge for registered participants in theexhibition area during the official coffee breaks.

Luncheons

Lunch will be available at the CCH Congress Center Hamburg or in several restau-rants nearby (not included in Congress-Fee).

Exhibition

An exhibition of the latest technical equipment and pharmaceutical products willbe open from May 22-24, 2003. For information on exhibition please contact:

AKM Congress Service GmbHMs. H. BrabecHauptstr. 1879576 Weil am RheinGermanyPhone: ++49 (0) 7621-9833-33Fax: ++49 (0) 7621-787 14E-mail: brabec.h@akmcongress.com

Travel

The Congress Center Hamburg is centrally located with easy transport links forfast and reliable travel. It is in the centre of Hamburg, right next to the Hamburg-Dammtor Intercity main line train station, at the edge of Planten un Blomen park.

AirHamburg Airport serves 114 destinations worldwide, with direct links to 52 Euro-pean cities. It is located in the North of the city, with easy connections by airportbuses, scheduled buses and taxis. Travel time from CCH to the airport is between20 and 30 minutes.Hamburg Airport online: www.ham.airport.de

RoadThe CCH ist already signposted at Hamburg’s motorway exits. The signpostsindicate the shortest route to CCH, which has 900 parking spaces in its ownunderground car park.

RailThe CCH is directly linked with the ICE, IC and Interregio network of Deutsche Bahn,with its own Intercity main line train station, Dammtor, just a few steps away.Timetable information of Deutsche Bahn: bahn.hafas.de

44

Public transportThe CCH is also easily accessible via public transport, linking it with the whole ofthe city areas.

S-Bahn: Rapid transmit lines S11, S21, S31 to Hamburg DammtorU-Bahn: Metro lines U1 to Stephansplatz or U2 to GänsemarktBuses: 102 and 109 to Dammtor, or 112 to StephansplatzExpress Buses: 34 to Dammtor, 35 to Heinrich-Hertz-Turm or 36 to Stephansplatz

Hamburg public transport online: www.hvv.de

Technical Equipment

Computer projection (beamer) ist preferred. Data beamer are available in eachroom. There will be no possibility for the use of slide projection or overheadprojector. Speakers are urged to bring their media on a Windows readable orMacintosh CD-ROM. Speakers wishing to use their own laptops have to make sureto have a VGA output.

Posters

All posters will remain hanging during the entire meeting.Postersize is max. 150 cm (high) x 98 cm (width).Mounting time: Wednesday, May 21, from 12.00 hr.Poster removal: Saturday, May 24, between 11.00 and 13.00 hr.Posters not removed by 13.00 h will be thrown away.

Media-Check

Speakers are required to bring their CD-ROM at least 45 minutes prior to thebeginning of their session to the Media-Check. Kindly leave the CD-ROM with theprojectionist who will take it to the lecture hall. Please remember to collect theCD-ROM from the projectionist after the session at the Media-Check.

No Smoking Policy

The Organizing Committee maintains its policy that the ISBS/ISSI Meeting be atotally non-smoking environment. Smoking will not be permitted anywhere at theMeeting.

Evaluation Forms

Evaluation and Suggestion Forms will be available at the registration area. Pleaseprovide any comments, criticism, suggestions, or anything else of value incritiquing the Meeting. The forms may be signed or remain anonymous.

GENERAL INFORMATION

45

Hamburg is one of the most beautiful cities in Germany - it has everything.

With its population of 1.7 million, the free and hanseatic city of Hamburg issituated some 60 miles from the North Sea estuary of the river Elbe.

Hamburg is unparalleled for its exciting mixture of world city culture, harbour flair,Alster romance and its townscape full of parks and tree-lined boulevards. Ham-burg is the second greatest city in Germany and boasts more bridges than Venice,London and Amsterdam put together.

In the heart of the city the Alster lake invites for rowing, sailing or simply for post-meeting relaxing. The other main water experience is the Elbe. The river is busywith huge overseas ships heading for Europe’s second largest port or already ontheir way back to the sea after a short rest, allowing the sailors a few hours ofleisure, mostly spend at St. Pauli, one of the worlds most famous entertainmentdistricts.

In its center lies the Reeperbahn, known for its reputation of being the worlds„most sinful mile“, although nowadays you will find the most exciting disco-theques, pubs and theaters in this area as well.

The city’s daytime attractions are no less unique. Take the network of some dozenarcades between Jungfernstieg and City Hall Square or Mönckebergstraße with itsdepartment stores and the shopping mall Levantehaus - shopping in Hamburg is

CITY OF HAMBURG

Landungsbrücken

46

fun. And if you are more interested in art and culture, Hamburg offers the finestexhibitions and performances in 40 museums and theaters.

During the summer months Hamburg has a very attractive climate with anaverage day temperature of around 20 degrees Celsius (70 degree Fahrenheit).

If you would like more information about Hamburg, you can visit the followingweb sites:

www.hamburg.de What’s on in Hamburgwww.hamburg-magazin.de What’s on in Hamburgwww.hamburg-tourism.de What to see and where to stay in Hamburg

Binnenalster

CITY OF HAMBURG

47

Discover Hamburg off your own bat!

Culturally Hamburg offers anything and everything starting at the Great Hall of Artand the State Opera, and continuing on to the music clubs on the Reeperbahn.

There are 31 theatres in Hamburg, 6 musical performing halls, 10 cabarets as wellas 50 public and private museums. Of the 4000 restaurants to choose from, 2400offer a wide range of international cuisine.

The banks of the Elbe and the Alster Rivers readily invite you to promenade alongtheir shores to your heart’s desire. Harbor sight-seeing boat trips are more thanimpressive and let you enjoy a view of the panorama from a very special vantagepoint.

There’s a grand lake right in the heart of the city center, the Alster. At the very endof a sight-seeing boat trip on the Alster, you are actually in the center of town,where you may shop to you heart’s content or take a much needed rest in a street-side café. You may go anywhere you like, very fast, for a small charge, if you hopon to any of the modern subway trains or the metro busses waiting there for you.

The countryside of Hamburg is especially charming and attractive. First the fruitplantations of the Altes Land with their fascinating antique farm houses, arewithout doubt worth the trip of getting there by bus or by bike. Then the historicold town centers of Stade or Lüneburg may be reached within half an hour. Finallyit will take you just an hour to get to Lübeck and the Baltic Sea coast by car.

Explore beautiful Hamburg on the weekend after the congress. We have arrangeda spectacular event for you on May 24 afternoon:

Dialogue in the dark® (www.dialog-im-dunkeln.de)An exhibition to discover the unseen. A fascinating journey challenging yoursenses. Please make your ticket reservation in advance (latest April 30, 2003 atschlachter.a@akmcongress.com or use the registration form). All guided tours arein english language.

Guided Tour No. 1 15:00 o’clockGuided Tour No. 2 15:45 o’clockGuided Tour No. 3 16:15 o’clockGuided Tour No. 4 16:45 o’clockGuided Tour No. 5 17:30 o’clock

Price per person: EUR 12,00

SOCIAL PROGRAM

48

SOCIAL EVENTS

Wednesday, May 21, 2003

20:00 hr Welcome Reception

Location: Historical Museum Ship(Rickmer Rickmers)

Joja Wendt live „sehr schwer zu spielen“(quite difficult to play)

The pianist and entertainer Joja Wendt is justas popular at international festivals as at hismany concerts in Germany. The Hamburgnative studied piano at the Conservatory inHilversum and at the Manhattan School ofMusic/New York. After that, he has gained alarge following primarily through his highlyindividual live interpretation of a wide rangeof musical styles including classical, blues,swing, boogie, ragtime and jazz. Joja Wendt isable to bridge the gaps between the variousgenres with an unique inspired sound withreflects both his virtuosity and creativity.

Joja Wendt has appeared on stage with international stars such as Chuck Berry,Jerry Lee Lewis, Lou Rawls, Fats Domino and Joe Cocker. He received the LouisArmstrong Jazz Prize in November 2000. Last Year he was admitted to the legendarycircle of the Steinway Artists, an honor usually reserved for classical pianists.

Piano music which appeals all generations and provides entertainment for all. Weconsider it as a great honor that Joja Wendt will entertain us during the Welcomereception with his energetic, enthusiastic and virtuoso mastering of the piano.Please note: For security reasons high heels are not allowed on the ship.

Admission free, Pre-registrationrecommendedFrom 19:30 hr Shuttle Bus available(one way)

Friday, May 23, 2003

20:00 hr Congress DinnerLocation: “Zippelhaus“

Price/Person: 7 60.00Students, Scientists in training: 7 40.00Pre-registration recommended

HOTEL RESERVATION FORM

1st Joint Meeting -14th Congress for Bioengineering and the Skin

and 8th Congress of the International Society for Skin ImagingHamburg, May, 21 – 24, 2003

Please return this form before April 22, 2003 to:Hamburg Messe und Congress GmbH (HMC), P.O. Box 302480, 20308 Hamburg – Germany

Phone: +49 (0)40 3569-2345 Fax: +49 (0)40 3569-2269 e-mail: ankevan.zuetphen@cch.de

Please use typewriter or capital letters

Surname Firstname

Company

Address

Postal Code City

Country e-mail

Phone Telefax

Hotel ReservationPlease reserve accommodation: ❑ single room ❑ double room

from __________________ to __________________ nights __________________ date of arrival date of departure

Hotel Single room Double room Deposit / Room

Radisson SAS Hotel EUR 158.00 173.00 150.00Elysée EUR 132.00 152.00 130.00Böttcherhof EUR 100.00 120.00 100.00Baseler Hof EUR 199.00 119.00 195.00

Rates are per room/night, incl. service, 16% VAT. – Rates don’t include breakfast, except at Baseler Hof – Hotel rooms will onlybe reserved after receipt of a guarantee only. - Rates are subject to change.

Preferred hotel ________________________ 2nd choice hotel ________________________

Deposit payment/Guarantee

❑ I have transferred the deposit to your bank account: Hamburg Messe und Congress GmbH,w / proderm 2003 Hamburgische Landesbank (BLZ 200 500 00) Account no. 228 130 240

❑ Please take my credit card as a guarantee: (a deposit is not required)

❑ Eurocard/Mastercard ❑ Visa ❑ Diners Club ❑ American Express

Credit card no.

Expiry date /

month year

Card holder’s name __________________________________________

_____________________________________________________________________________________________Date Signature

With my signature I accept the conditions mentioned on this reservation form – see other side.✁

EXHIBITION ANDCONGRESS MANAGEMENTA JOB FORSPECIALISTSAKM experts are always therewhen you need them

AKM Congress Service GmbH, Hauptstrasse 18, D-79576 Weil am RheinTelefon (+7621) 98 33-0, Telefax (+7621) 78 714, E-mail: akmweil@akmcongress.com

A •K •MCongress ServiceGmbH

SOCIAL/CULTURALEVENTS

PLANNING

FINANCING

VENUE

EXHIBITION

ADMINISTRATION

51

HOTEL RESERVATION FORM

PLEASE NOTE:

All reservations received later than April 22, 2003 must be confirmedby a credit card number.

(Bank transfers are longer possible.)Reservations without a credit card number will not be handled.

CONDITIONS FOR HOTEL RESERVATIONSDeadline: April 22, 2003

Confirmation/Deposits:

Hotel rooms can only be reserved upon receipt of a deposit or a credit cardnumber. All requests for hotel reservations and all deposits must be received bythe HMC no later than April 22, 2003. If the desired hotel is fully booked, the HMCreserves the right to arrange accommodation in a different hotel.

For reservations and payments received later than the above mentioned date, allnecessary efforts to procure a hotel room for you will be done. Please be awarethat a guarantee for your hotel preference and/or the rates indicated cannot begiven by the HMC. Upon receipt of the deposit, the guest will receive a hotelvoucher with the amount of the deposit. This voucher must be presented uponarrival at the hotel. Any further hotel expenses are to be paid directly at the hotelby the guests themselves.

Changes/Cancellation:

Changes in reservations and cancellations must be reported in writing to the HMC.Upon receipt of the reservation confirmation, the guest automatically becomes thelegally binding contract partner of the hotel. HMC acts exclusively as an agent forhotel reservations. In the event of an early departure, the hotel is entitled tocharge the entire reserved period, unless the room is taken by another guest. If theguest cancels a reservation prior to April 22, 2003, the deposit minus a cancella-tion fee of EUR 26,00 (incl. 16% VAT) per room reservation on behalf and for theaccount of HMC will be refunded; any bank charges that may arise as a result ofsuch a cancellation will be covered by the guest him-/herself. No refund will bemade after this date. If however the hotel is able to rebook the room for anotherguest, the deposit minus the cancellation fee will be refunded. All costs must beborne by the guest.

Credit card guarantee:

The guest guaranteeing his hotel reservation by credit card herewith entitles theHMC to forward the data of the credit card to the hotel as a guarantee for the roomreservation. A deposit is not required.

52

LIST OF SPONSORS

The organizing committee expresses its thanks and appreciation to all those whoare generously contributing to the success of the 1st Joint Meeting, 14th Interna-tional Congress for Bioengineering and the Skin and 8th Congress of the Interna-tional Society for Skin Imaging:

Gold-Sponsors:

CuDerm Corporation

Leo Pharmaceutical Products Ltd.

L’Oréal

Sponsors:

Aco Hud AB

Ajinomoto Co. Inc.

Authority for commerce and Labour of the free and hanseaticcity of Hamburg

Beiersdorf AG

BioTesys GmbH

Colgate Palmolive

Courage & Khazaka Elektronik GmbH

GF Messtechnik GmbH

ISIS optronics GmbH

Pentapharm Ltd.

Procter & Gamble GmbH

Spirig Pharma Ltd.

As of: March 31, 2003

An actualized list is available on the homepage of the meeting.

53

LIST OF EXHIBITORS

in numerical order

101 SIT Skin Investigation and Technology, Hamburg/D103 Delfin Technologies Ltd., Kuopio/SF105 taberna pro medicum GmbH, Lüneburg/D111 ISIS optronics GmbH, Mannheim/D115 Biox Systems Ltd., London/UK117 Breuckmann GmbH, Meersburg/D119 BioSkin GmbH, Hamburg/D, Berlin/D123 Courage + Khazaka electronic GmbH, Köln/D131 Perimed AB, Järfälla/S135 Cardiff Biometrics Ltd., Cardiff/UK137 Lawrenz Medizinelektronik GmbH, Bad Soden/D139 Aster Cosmetology, Paris/F143 CORTEX Technology, Hadsand/DK151 Optiscan, Melbourne/AUS153 proDERM Institute for Applied Dermatological Research, Schenefeld/D155 m.u.t GmbH, Wedel/D157 GFMesstechnik GmbH, Teltow/D159 Canfield Clinical Systems, Fairfield/USA

in alphabetical order

139 Aster Cosmetology, Paris/F119 BioSkin GmbH, Hamburg/D, Berlin/D115 Biox Systems Ltd., London/UK117 Breuckmann GmbH, Meersburg/D159 Canfield Clinical Systems, Fairfield/USA135 Cardiff Biometrics Ltd., Cardiff/UK143 CORTEX Technology, Hadsand/DK123 Courage + Khazaka electronic GmbH, Köln/D103 Delfin Technologies Ltd., Kuopio/SF157 GFMesstechnik GmbH, Teltow/D111 ISIS optronics GmbH, Mannheim/D137 Lawrenz Medizinelektronik GmbH, Bad Soden/D155 m.u.t GmbH, Wedel/D151 Optiscan, Melbourne/AUS131 Perimed AB, Järfälla/S153 proDERM Institute for Applied Dermatological Research, Schenefeld/D101 SIT Skin Investigation and Technology, Hamburg/D105 taberna pro medicum GmbH, Lüneburg/D

54

EXHIBITON FLOOR PLAN

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