11. – 13. 9. 2014, athens 8th european conference on medical physics dosimetry audits in...

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11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl Ivana Horáková Vladimír Dufek Michaela Kapuciánová National Radiation Protection Institute Prague, Czech Republic

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Page 1: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

11. – 13. 9. 2014, Athens

8th European Conference on Medical Physics

DOSIMETRY AUDITS IN RADIOTHERAPY

IN THE CZECH REPUBLIC

Irena KoniarováDaniela EkendahlIvana HorákováVladimír Dufek

Michaela Kapuciánová

National Radiation Protection InstitutePrague, Czech Republic

Page 2: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

Situation in the Czech Republic

Population ≈ 10 million

Radiotherapy patients ≈ 22 thousand per year

Radiotherapy departments

Total number 36

- using high energy beams 28

- using IMRT or IMAT 18

Page 3: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

Irradiation units infrastructure

Page 4: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

Independent audits

Physical segment of radiotherapy

TLD postal audit

On-site audit

performed regularly for purposes of the State Office for Nuclear Safety or on request of radiotherapy centres

Whole system of radiotherapy

Clinical audit

in progress

National Radiation Protection Institute

License holder

Page 5: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

TLD auditBiennial

LA, Co-60, Cs-137 (1435 beams)

Beam calibration check

Dose checks for various non-reference conditions

Assymetric fields

Rectangular fields

Wedge fields

Oblique incidence

inhomogeneities

Basic TLD audit TLD audit using phantoms

Dose checks in radiation fields formed by MLC

TLD audit of LA with MLC

Methodologies were developed in the frame of IAEA’s CRP

Page 6: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

On-site audits of radiotherapy equipment after acceptance test

LA and gamma units (535 beams), X-ray units (103), BRT (32)

Checks of selected dosimetric and geometric parameters

Check of non-dosimetric parameters and imaging functions of TPS using QUASAR phantoms

Basic audit TPS audit

LA with MLC and IMRT

Check of selected parameters

Advanced audit

Page 7: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

On-site audits of IMRT prostate treatment21 plans verified in 2013

Check of dose to PTV and rectum, evaluation of DVH

use of a special pelvic phantom representing standard patient

measurements with ionizing chambers and gafchromic films

use of QUASAR phantoms (CT numbers to RED)

DVH analysis – gEUD (PTV, rectum, bladder), HI, NTCP (rectum)

Page 8: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

TLD audit – Results of beam calibration checks in 1997 - 2012

< -10 -10 -6 -3 0 3 6 100

10

20

30

40

50

60

70

80

1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

[%]DD

Nu

mb

er

of

be

am

s

N = 1332 m = -0.2% s = 3.0%

D = (DTLD/Ds - 1) · 100%D 3% - acceptance level

Page 9: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

On-site audit – Results in 1996 - 2000

Page 10: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

On-site audit – Results in 2001 - 2004

Page 11: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

On-site audit – Results in 2005 - 2008

Page 12: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

On-site audit – Results in 2009 - 2013

Page 13: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

End-to-end audit results21 plans evaluated

Mean total deviation from planned dose in PTV 0,991 ±0,004 (deviation expressed as measured to planned doses) Mean deviation for beam calibration

in water 1,008 ± 0,002

Mean deviation due to the transition from water to phantom material 0,981± 0,002

Mean deviation due to the transition from a square field in the phantom to IMRT field in the phantom 1,003 ± 0,003

4 plans out of tolerance limit (3%) for total dose in PTV

Gamma criteria 4%/3 mm, tolerance: 95% pixels in the dose matrix to satisfy

5 plans out of tolerance (in 4 cases because of the uncertainties in phantom positioning on the couch)

Dosimetry part Planning part

Comparison to QUANTEC

Prescription according to ICRU except 2 cases

Homogeneity in PTV was outstanding

Different doses to rectum (based on gEUD intercomparison, regarding the uncertainty in the parameter a)

Page 14: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

On-site and TLD audits - experience

to pay more attention to acceptance tests of RT equipment

to reserve enough time for commissioning of new equipment and new methods

relevant education, experience and training of the staff

On-site audits: prevention of accidental exposure

All serious errors were caused by human mistakes and were related to the performance of acceptance test.

TLD audit contributes to improvement of clinical dosimetry, and it is appreciated by most of radiotherapy departments

The more advanced versions of TLD audit are very useful for dose verification in non-reference conditions, they can help to reveal some potential problems

The role of TLD audit

Page 15: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

Future plans

Continue with on-site audits after acceptance test and regular TLD postal audits

Implement end-to-end test with prostate phantom into the system of audits (i.e. after implementation of new technology in department)

Repeat end-to-end test for more complex techniques – IMRT of head and neck (dosimetry and planning)

Participate in the IAEA activities – audit with CIRS Thorax Phantom

Page 16: 11. – 13. 9. 2014, Athens 8th European Conference on Medical Physics DOSIMETRY AUDITS IN RADIOTHERAPY IN THE CZECH REPUBLIC Irena Koniarová Daniela Ekendahl

Thank you!