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Introductory Biochemistry Bioch 200 Course Outline and Objectives

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Page 1: 1 Introduction

Introductory Biochemistry

Bioch 200

Course Outline and Objectives

Page 2: 1 Introduction

Biochemistry 200Introductory Biochemistry

Section A3

TR 12:30-1:50 amTelus 150

Dr. Jonathan Parrish

Source: http://xkcd.com

Page 3: 1 Introduction

How to contact your instructor

Dr. Jonathan Parrish

Department of Biochemistry

Room 5-79 MSB

[email protected]

780-492-2866

Office Hours:

Wednesday 10:00am-12:00noon

Page 4: 1 Introduction

Other ContactsDr. A. Wright

Biochemistry 200 Course Coordinator5-81A Medical Sciences [email protected]; 492-8065

Ms. Shannon Swan Biochemistry Student Services

5-81 Medical Sciences [email protected]; 492-5006

Page 5: 1 Introduction

Prerequisites

CHEM 101: Introductory University Chemistry I

CHEM 164 or 261: Organic Chemistry I

Check your registration, contact Shannon Swan if you have concerns regarding your registration status.

The add/withdraw deadline for Winter term is September 21!

Page 6: 1 Introduction

Course Content1. Introduction

2. Biomolecules

3. Nucleotides and Nucleic Acids

4. Protein Structure and Function

5. Enzymes

6. Biological Membranes

7. Introduction to Metabolism

8. Glucose Metabolism

Page 7: 1 Introduction

BIOCH 200: Course Objectives

A one-term overview of the scope of biochemistry.

An introduction to the subject’s extensive terminology.

Emphasis on relevance to other fields (medicine, nutrition, athletic performance).

A foundation for further study in diverse subjects (medicine, pharmacy/pharmacology, kinesiology, nutrition, agriculture).

Page 8: 1 Introduction

Who takes Bioch 200?

Page 9: 1 Introduction

Who wants to take Bioch 200?

Page 10: 1 Introduction

Support Materials Textbook “Essential Biochemistry”

by Charlotte W. Pratt & Kathleen Cornely

Practice Questions Recommended from the textbook Problem Sets

Posted on WebCT Exam Questions

Posted on WebCT

Learning Objectives Posted on WebCT and in PowerPoint lectures

Page 11: 1 Introduction

iClickers

• These can be obtained at the Bookstore.• Other courses may also use them• There is a refund/return policy for the

iClickers

Answers will not be graded or assessed, but participation will be evaluated.

Page 12: 1 Introduction

iClicker Assessment Answers will not be graded

Participation will be assessed 1% if participate 25-50% 3% if participate 51-75% 5% if participate >75%

Page 13: 1 Introduction

Register your iclicker

http://www.iclicker.com/registration/ First Name:

Last Name: Student ID: User ID for eClassClicker ID:

Register by September 14th 2010 If you purchase your iClicker and it has already been registered please follow the

same directions as if it were new. If the barcode has faded please bring your iClicker to me after class or to

Shannon in Rm 5-81 MSB.

Page 14: 1 Introduction

Brainspan Game System

https://maggie.srv.ualberta.ca/brainspan/

Practice Exam Questions

YOU MUST change your alias (Starts as userid)

Page 15: 1 Introduction

Exam Schedule: BIOCH 200 Midterm I – October 7th

20%

Midterm II – November 10th

20%

Final Exam – December 22nd

55% (Cumulative) Consolidated exam

Check the University exam schedule when it is posted.

Page 16: 1 Introduction

Introductory Biochemistry

eClasswww.ualberta.ca/ELEARNING/

www.ualberta.ca/helpCall the Help Desk at 492-9400

[email protected]

Page 17: 1 Introduction

Regulations Pertaining to Deferred Examinations

Do not miss exams. Medical excuse required. See Dr. Wright for permission to write

deferred exams. All deferred midterm examinations will

occur on December 9th. Deferred exams are short answer, not

multiple choice.

Page 18: 1 Introduction

How to do well in this course

Attend class. Review learning objectives and make sure

you can meet them all. Do the practice questions. Read the text and do the recommended

exercises.

Page 19: 1 Introduction

Study!

http://www.youtube.com/watch?v=2ArIj236UHs

Page 20: 1 Introduction

Fundamentals of Biochemistry

1. IntroductionWhat is Biochemistry?

Page 21: 1 Introduction

What is Biochemistry?

The scientific discipline that seeks to explain life at the molecular level.

A means for determining how organisms “work” using the tools and terminology of chemistry.

A practical science with wide-ranging applications in a range of life science subjects, in treatment of diseases, and in industry.

Page 22: 1 Introduction

Levels of Organization in Organisms

Page 23: 1 Introduction

Fundamentals of Biochemistry

1. IntroductionBiomolecules

Page 24: 1 Introduction

Elements in Biological Systems

Page 25: 1 Introduction

Biomolecules

simple molecules H2O, CO2, NH3, O2, N2

building blocks amino acids, carbohydrates, nucleotides, lipids

polymers proteins, polysaccharides, nucleic acids

supra-molecular assemblies ribosomes, chromatin, membranes, etc.

organelles

cells

tissues, organs

Page 26: 1 Introduction

The Four Major Classes of Biomolecule

amino acids

carbohydrates

nucleotides

lipids

Page 27: 1 Introduction

Representing Biomolecules

Page 28: 1 Introduction

Functional Groups and Linkages

Page 29: 1 Introduction

Table 1.1

Page 30: 1 Introduction

Table 1.1

Page 31: 1 Introduction

Biopolymers

Page 32: 1 Introduction
Page 33: 1 Introduction

Biopolymers

Page 34: 1 Introduction

Functions of Biopolymers

Biopolymer Encode Information

Metabolic Reactions

Store Energy

Cellular Structures

Proteins No Yes Somewhat Yes

Nucleic Acids Yes No No No

Polysaccharides Somewhat No Yes Yes

Page 35: 1 Introduction

Introductory Biochemistry

1. IntroductionWater

Page 36: 1 Introduction

Water

Page 37: 1 Introduction

Water

Page 38: 1 Introduction
Page 39: 1 Introduction
Page 40: 1 Introduction

Van der Waal’s Interactions

Page 41: 1 Introduction
Page 42: 1 Introduction

Bond Strength in Biological Molecules

Page 43: 1 Introduction

The Electronegativity of Atoms

Page 44: 1 Introduction

Groups That Can Make H Bonds

Page 45: 1 Introduction

Solubility in Water: Hydrophilic Interactions

Page 46: 1 Introduction

The Hydrophobic Effect

Page 47: 1 Introduction

The Hydrophobic Effect

Page 48: 1 Introduction

Amphiphilic molecules experience hydrophilic interactions and the hydrophobic effect.

Page 49: 1 Introduction

Amphiphilic molecules experience hydrophilic interactions and the hydrophobic effect.


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