ZBIGNIEW J. WITCZAK

Department of Pharmaceutical Sciences Nesbitt School of Pharmacy, Wilkes University,

Wilkes-Barre, PA 18766 Phone: (570) 408-4276; Fax:(570) 408-7828

E-mail: zbigniew.witczak@wilkes.edu;

ACADEMIC AND PROFESSIONAL APPOINTMENTS 2013 - present Professor and Chair, Department of Pharmaceutical Sciences, School of Pharmacy, Wilkes University, Wilkes-Barre, Pennsylvania 2007 – 2013 Professor of Medicinal Chemistry, Department of Pharmaceutical Sciences, School of Pharmacy, Wilkes University, Wilkes-Barre, Pennsylvania 2000 - 2007 Associate Professor, Department of Pharmaceutical Sciences, School of Pharmacy, Wilkes University, Wilkes-Barre, Pennsylvania 1991 - 1999 Associate Professor, Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, Storrs, Connecticut. 1987 - 1991 Senior Research Chemist, Project Leader, Food and Industrial, Research & Development,

A. E. Staley Manufacturing Company, Decatur, Illinois. 1983 - 1987 Research Associate, Department of Biochemistry, Purdue University, West Lafayette, Indiana. 1981 - 1983 Post-Doctoral Training (with Prof. R. L. Whistler), Dept. of Biochemistry, Purdue University, EDUCATION 1979 Ph.D. Organic Chemistry of Natural Products, “Reaction of Flavones and their Precursors, Chalcones

and β-diketones with Hydroxylamine,” Department of Natural Products Chemistry, Faculty of Pharmacy, Medical University, Lódz, Poland.

1973 M.S. Organic Chemistry, Hydrogenolysis of N, N-α,β-Dicyanoethylhydrazine, Medical University, Lódz. HONORS AND AWARDS

• Elected US Representative as President of the International Carbohydrate Organization 2016-2018 • Distinguished fellow of the Collegium of Eminent Scientists, The Kosciuszko Foundation, 2015 • Selected 2011 ACS Fellow, American Chemical Society, Washington DC. 2011 • Outstanding Faculty, Nesbitt School of Pharmacy and Nursing, Wilkes University, September 2006 • Elected US Representative to the International Carbohydrate Organization, 2006 • Elected Teacher of the Year, Nesbitt School of Pharmacy, Wilkes University, 2003. • Melville L. Wolfrom Award of the Division of Carbohydrate Chemistry of the ACS, 2000. For outstanding

research contribution to carbohydrate chemistry and service to the Division of Carbohydrate Chemistry. • John S. Burlew, Connecticut Valley Section Award of American Chemical Society, 1997. For outstanding

research contribution to carbohydrate chemistry. • Elected Teacher of the Year, School of Pharmacy, University of Connecticut, 1996. • 2nd Prize-Paper presentation at 1st International Glupor Meeting, Lisbon, Portugal, Sep. 26, 1995

• Annual Inventor Award 1980 • 1st Class honors in Ph.D. 1979 . • Outstanding Teacher Award, 1979.

PROFESSIONAL SERVICE IN GRADUATE EDUCATION • External Examiner, Ph.D. Dissertation Committee, Dep. of Chem. Binghamton Univ. May 9, 2013.

• External Examiner, M.Sc. Examination Committee, Dep. of Chem. Lodz Univ. July 6, 2014. • External Examiner, M.Sc. Examination Committee, Dep. of Molecular Genetics Lodz Univ. July 2, 2014. • External Examiner, Ph.D. Dissertation Committee, Dep. of Chem. Univ. of Cape Town, May 9, 2015.

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• External Examiner, Ph.D. Examination Committee, Dep. of Molecular Genetics Lodz Univ. June 6, 2016.

PROFESSIONAL SOCIETIES • American Chemical Society 1986 -present

• Polish Chemical Society 2012-present • Argentinian Chemical Society- Honorary member 2005- present • American Association of Colleges of Pharmacy 1991- present

PROFESSIONAL EDITORIAL APPOINTMENTS • Member of the Editorial Board of the - SOJ Pharmacy & Pharmaceutical Sciences, 2013-. • Associate Editor & Member of the Editorial Board of Current Organic Synthesis, 2003- • Associate Editor & Member of the Editorial Board of Mini Reviews in Organic Synthesis, 2003- • Member of the Editorial Board of the - Open Glycoscience, 2007- • Member of the Editorial Board of the - Carbohydrate Research, 2003-2009. • Member of the Editorial Board of the -Letters in Organic Chemistry, 2003-. • Associate Guest Editor of –Special Anthracyclines Issue Current Medicinal Chemistry, 1999- • Member of the Editorial Board & Associate Guest Editor of Carbohydrate Chemistry Topics -Current Organic Chemistry, 1999-2008 • Associate Guest Editor of –Special Carbohydrate Issue Current Medicinal Chemistry, 1999- • Member of the Editorial Board of the – The Investigational Drugs Journal, 1998-2002 • Member of the Editorial Board & Associate Guest Editor of -Current Medicinal Chemistry, 1997-

• Book Review Editor-Coordinator -Journal of Carbohydrate Chemistry, 1995-. • Member of the Editorial Board of the -Journal of Carbohydrate Chemistry, 1994-. CITATIONS

• American Men and Women in Science • Who is Who in Polish Americans CONSULTANTSHIPS/SCIENTIFIC ADVISORY BOARDS

• Cultor Food Science Inc. Research Center, Ardsley, NY, 1998-1999 • Glycogenesis (formerly Safe Science Inc.), Boston, MA, 1996-2000 • Proctor & Gamble Pharmaceuticals, Miami Research Center, Cincinnati, 1996 • Grain Processing Corporation Research Center, Muscatine, Iowa, 1995-1997 • Biorefining Inc. Minneapolis, MN, 2000-2008. • Pro-Pharmaceuticals, Inc. Newton, MA, 2003-2010. • Boston Therapeutics Inc. Manchester, NH, 2014

PROFESSIONAL SOCIETY SERVICE AND AFFILIATIONS

• Member of the Selection Committee for the ACS Ernest Guenther Award in Chem. of Natural Products 2012 • Member of the Award Committee for the ICO Young Researcher Award in Carbohydr. Chem. 2013 • Treasurer, Division of Carbohydrate Chemistry, American Chemical Society 2005-2009, 2009-2013 • Chair Award Committee, Division of Carbohydrate Chemistry, American Chemical Society 2003-2005 • Past-Chair, Division of Carbohydrate Chemistry, American Chemical Society 2002. • Chair, Division of Carbohydrate Chemistry, American Chemical Society 2002. • Elected Chair-Elect, Division of Carbohydrate Chemistry, American Chemical Society 2001-2002. • Elected Executive Secretary, Division of Carbohydrate Chemistry, American Chemical Society ‘98-’2000. • Elected Secretary, Division of Carbohydrate Chemistry, American Chemical Society ‘96-’98. • Elected Chairman Membership Committee, Division of Carbohydrate Chemistry, 1994 -

• Elected to the Executive Committee of the Division of Carbohydrate Chemistry, ‘90-’92 and ‘92-’94. • Member of American Society of Pharmacognosy 1992-.

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• Member of International Union of Pure and Applied Chemistry (IUPAC). 1992-. AD HOC REVIEWER FOR PEER GRANT REVIEW COMMITTEES • Petroleum Research Fund ACS, Washington, DC. Feb. 1999, Jan. 2000. Aug. 2000. Jun. 2001, Aug. 2002

• Engineering & Physical Sciences Research Council, Swindon, England, September 1998. • Research Corporation, Tucson, Arizona, August 1998. • National Science Foundation, Washington D.C. September 1997. January 2002, May 2002, August, 2003 • Australian Research Council, Canberra, Australia, May 1997. • Hunter College, CUNY, New York, December 1996, 2012. • Monash University, Melbourne, Victoria, Australia, February 1996, February 1997

• Israel Science Foundation, Jerusalem, Israel, March 1996.March 2002, March 2007 • Mississippi-Alabama Sea Grant Consortium, June 1995, March, 1996, April, 1996, June 1997. July 2000. • International Foundation for Science, Stockholm, Sweden, May 2002

• FWF Der Wissenschaftsfonds, Vienna, Austria, May 2003 • European Research Council, Brussels, Belgium, April 2017 AD HOC REFEREE OF CHAPTERS AND MANUSCRIPTS FOR • American Chemical Society Books • Journal of Natural Products • Chemistry & Biology • Bioorganic & Med. Chem. Letters • Journal of Carbohydrate Chem. • Letters in Organic Chem • Bioorganic & Medicinal Chemistry • Carbohydrate Research • Biopolymers • Journal of Organic Chemistry • Tetrahedron • • Tetrahedron Letters • FEBS Letters • • Journal of Medicinal Chemistry • Current Medicinal Chemistry • Organic Letters • Current Pharmaceutical Design • Current Organic Synthesis • Chemistry A Eur. Journal • Current Organic Chemistry • Advanced Synthesis & Catalysis • Chemical Papers • Archive der PHARMAZIE • Pure and Applied Chemistry • Eur Journal of Org Chem • Synlett • Marine Drugs • Molecules • ACS Catalysis • Synthesis • INTERNATIONAL/NATIONAL SYMPOSIUMS ORGANIZED (19)

• Vice-Chair of the 28th International Carbohydrate Symposium, New Orleans, July 17-22, 2016, USA, • Organizer and Chairman of the Symposium “Derek Horton Memorial Symposium” at 28th International

Carbohydrate Symposium, New Orleans, July 17-22, 2016, USA, • Organizer and Chairman of the Symposium “Strategies for Coupling and Decoupling Diverse Molecular

Units in the Glycosciences” Pacifichem 2015, December 15-20, 2015, Honolulu, Hawaii. • Organizer and Chairman of the Symposium “Rearrangement and Domino Reactions in Carbohydrate

Chemistry” (ACS Sponsored) August 11, 2014, San Francisco, CA. • Organizer and Chairman of the Symposium “Click Chemistry Approaches in Carbohydrate Chemistry”

(ACS Sponsored) March 28, 2011, Anaheim, CA. • Organizer and Chairman of the Symposium “Carbohydrate Organic Intermediates” (ACS Sponsored)

March 21-22, 2009, Salt Lake City, UT. • Organizer and Chairman of the Symposium “Sugars as Organic Intermediates” (ACS Sponsored) August

19-23, 2007, Boston, MA. • Organizer and Co-Chairman of the Symposium “Organic Chemistry of Carbohydrates: Legacy of

Aleksander Zamojski” (ACS Sponsored) March 26-27, 2007, Chicago, IL. • Organizer and Chairman of the Symposium, “Wolfrom/Isbell/New Investigator Award Symposium” (ACS

Sponsored) September 10, 2006, San Francisco CA. • Organizer and Chairman of the Symposium “Carbohydrate Chemistry” MARM 2006, June 4-6, 2006 Hershey, PA

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• Organizer and Chairman of the Symposium, “Wolfrom/Isbell/New Investigator Award Symposium” (ACS Sponsored) August 29, 2005, Washington DC.

• Organizer and Chairman of the Symposium, “Wolfrom/Isbell/New Investigator Award Symposium” (ACS Sponsored) August 23, 2004, Philadelphia, PA.

• Organizer and Chairman of the Symposium, “Wolfrom/Isbell/New Investigator Award Symposium” (ACS Sponsored) September, 5, 2003, New York,, NY

• Organizer and Chairman of the Symposium, “Claude Hudson Award Symposium” (ACS Sponsored) March 23, 2003, New Orleans, LA

• Organizer and Co-Chairman of the Symposium, “Carbohydrates as Precursors for Multiple Synthetic Targets” (ACS Sponsored) August 23, 2002, Boston. MA

• Organizer and Chairman of the Symposium “Carbohydrate Synthons in Natural Product Synthesis” (ACS Sponsored), March 22-25, 2000, San Francisco, California,

• Organizer and Chairman of the Symposium “Glucosidase & Fucosidase Inhibitors” (ACS Sponsored), April 1, 1998, Dallas Texas,

• Organizer and Co-Chairman of the Symposium, “Thio Sugars: Their Chemistry and Biological Importance,” (ACS Sponsored) April 5, 1995, Anaheim California.

• Organizer and Chairman of the Symposium “Levoglucosenone and Levoglucosans: Chemistry and Application” (ACS Sponsored), August 24, 1992, Washington, D.C.

INTERNATIONAL AND NATIONAL MEETINGS SYMPOSIA CHAIR (29)

• 28th International Carbohydrate Symposium, New Orleans, July 17-22, 2016, USA, • Pacifichem 2015, Honolulu, Hawaii, USA, December 16, 2015. • 18th European Carbohydrate Symposium, Moscow, Russia, August 2-6, 2015 • 19th European Symposium of Organic Chemistry (ESOC 2015), Lisbon, Portugal July 12, 2015 • American Chemical Society Carbohydrate Division, San Francisco, CA, August 11, 2014 • American Chemical Society Carbohydrate Division, New Orleans, LA, April 6-11, 2013 • American Chemical Society Carbohydrate Division, Philadelphia, PA, August 19-24, 2012 • 27th International Carbohydrate Symposium, Madrid, Spain, July, 22-27, 2012 • 25th International Symposium on the Organic Chemistry of Sulfur, Czestochowa, Poland, June 24-29, 2012 • American Chemical Society Carbohydrate Division, Anaheim, CA, March 28, 2011 • American Chemical Society Carbohydrate Division, Salt Lake, UT, March 21, 2009 • 1st International Conference of Drug Discovery & Development, Dubai, UAE, February 4-7, 2008 • American Chemical Society Carbohydrate Division, Boston, MA, August 19-22, 2007. • American Chemical Society Carbohydrate Division, Chicago, IL, March 19-23, 2007. • American Chemical Society Carbohydrate Division, San Francisco, CA, September 10, 2006. • American Chemical Society Carbohydrate Division, Philadelphia, PA, August 22, 2004. • American Chemical Society Carbohydrate Division, New York, NY, September, 5, 2003. • American Chemical Society Carbohydrate Division, New Orleans, LA March 23, 2003. • American Chemical Society Carbohydrate Division, Boston, MA August 18-22, 2002. • American Chemical Society Carbohydrate Division, Orlando, FL, April 7-11, 2002. • American Chemical Society Carbohydrate Division, San Diego, CA, April, 2001. • American Chemical Society Carbohydrate Division, San Francisco, CA, March, 2000. • American Chemical Society Carbohydrate Division, New Orleans, LA, August, 1999. • American Chemical Society Carbohydrate Division, Anaheim, CA, March, 1999. • American Chemical Society Carbohydrate Division, Dallas, TX, April 1998. • American Chemical Society Carbohydrate Division, Anaheim, CA, April 1995.

• 19th IUPAC Symposium on Chemistry of Natural Products, Karachi, Pakistan, January, 1994. • American Chemical Society Carbohydrate Division, Washington DC, August 1994. • American Chemical Society Carbohydrate Division, Washington, DC, August 1992.

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INVITED LECTURES AT INTERNATIONAL MEETINGS (16) 1. “Synthesis of C-glycosyl Compounds and Other Natural Products from Levoglucosenone,” 19th IUPAC

Symposium on Chemistry of Natural Products, Karachi, Pakistan, January, 1994. Abstract # CARB 00. 2. “Synthesis of C-Trisaccharide Analogues of Sialyl Lewisx from Levoglucosenone,” Z. J. Witczak,

presented at XVIIth International Carbohydrate Symposium, July 17- 22, 1994, Ottawa, Canada. Abstract # CARB 0038.

3. “Levoglucosenone: Chiral Synthon for the Synthesis of C- S- and N-Glycosides,” presented at the XVIII the IUPAC International Carbohydrate Symposium, Milano, Italy, July 21st-26th, 1996. Abstract # CARB 00.

4. “Stereoselective Synthesis of C-, S-, and N-Glycosides of Therapeutic Potential from Levoglucosenone,” Glupor II- 2nd International Meeting of the Portuguese Carbohydrate Chemistry Group, Porto, Portugal, Sept. 21-25, 1997. Abstract # CARB 00.

5. “Thio-sugars: New Synthetic Approaches and Importance of Sulfur Bridge for Design of Biological Activity” First Euroconference on Carbohydrates in Drug Research, Stintino, Sardinia, Italy, September 16-19, 1999. Abstract # CARB 00.

6. “Novel Thio-disaccharides as Potential Therapeutics of Diverse Biological Activities: Synthetic Studies and New Developments,” presented at 22th International Carbohydrate Symposium, Cairns, Australia, July 5, 2002. Abstract # CARB 00.

7. “A New Paradigm for Carbohydrate Therapeutics Discovery: Nonhydrolyzable Bioisosters of N, S-Thio-disaccharides,” XV SINAQO National Organic Chemistry Symposium, Mar-del Plata, Argentina, November 6, 2005. Abstract # CARB 00.

8. "Synthesis of S-, C-linked Thiodisaccharide Mimics as Potentials Tools for Glycobiology" Pacifichem 2005, Honolulu, Hawaii, December 15, 2005. Abstract # BIOL 0008.

9. "New Stereoselective Functionalization of Cellulose Derived Pyrolysis Derivatives: Levoglucosenone and its Dimer." Pacifichem 2005, Honolulu, Hawaii, December 19, 2005. Abstract # AGRO 0356.

10. “Thio-sugars as Emerging Targets for Carbohydrate Therapeutics Discovery” 1stInternational Conference on Drug Design & Discovery, Dubai, United Arab Emirates, February 4-7, 2008. Abstract # CARB 00.

11. “New Analogs of Thiolactomycin as Emerging Targets for Antitubercular and Antimalarial Carbohydrate Drug Discovery” Invited Lecture at 23th International Carbohydrate Symposium, Oslo, Norway, July 27-August 1, 2008. Abstract # CARB 00.

12. “Thio-sugars as Emerging Targets for Antimalarial and Antitubercular Carbohydrate Therapeutics Discovery” Plenary Lecture at Glupor 8 International Meeting of the Portuguese Carbohydrate Group. University of Minho, Braga, Portugal, September 6-10, 2009. Abstract # CARB 00.

13. “Thio-click and domino reaction approach in carbohydrate chemistry” Z. J. Witczak, presented at 27th International Carbohydrate Symposium, January 12-17, 2014, Bangalore, India, Abstract # I-A-LL-4.

14. “Thio-sugar motif of carbohydrate functionalized pharmacophore as strategic approach to the design of carbohydrate therapeutics” Z. J. Witczak, presented at 18th European Carbohydrate Symposium, August 2-6, 2015, Moscow, Russia, Abstract # KL-12.

15. “Sequential thiols recognition in coupling of functionalized carbohydrates” Z. J. Witczak, presented at the Pacifichem 2015, Honolulu, Hawaii, December 15-20 2015, Abstract BIOL-220

16. “Derek Horton; Prolific scientist, Editor, and wise mentor” Invited Lecture at 28th International Carbohydrate Symposium, New Orleans, LA, USA, July 17- 21, 2017. Abstract # 379.

INVITED LECTURES AT INTERNATIONAL SCIENTIFIC INSTITUTIONS (11)

1. “Synthesis and Structural Study of Anhydrosugars as Useful Synthons,” Department of Chemistry, Gifu University, Japan, August, 1990.

2. “Synthetic Approaches to C-Glycosyl Compounds and C-Oligosaccharides from Levoglucosenone,” Institute of Organic Chemistry, Polish Academy of Science, Warsaw, Poland, August, 1993.

3. “Synthetic Approaches to C-, S-, and N-, Glycosyl Compounds and C-Oligosaccharides from Levoglucosenone,” Institute of Organic Chemistry, Polish Academy of Science, Warsaw, Poland, August 13, 1996.

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4. “Levoglucosan, Levoglucosenone and Rare Sugars As Convenient Chiral Precursors for the Synthesis of Value Added Products in Food Industry,” Cultor Food Science Inc. Research Center, Kantvik, Finland, December 2, 1998.

5. “Novel Thio-disaccharides as Potential Therapeutics of Diverse Biological Activities: Synthetic Studies and New Developments,” Institute of Organic Chemistry, Polish Academy of Science, Warsaw, Poland, August 14, 2002.

6. “Thio-Disaccharides and their Potential Biological Activity”, Department of Organic Chemistry, Faculty of Science and Natural Products, University of Buenos Aires, Buenos Aires, Argentina, November 5, 2005.

7. “Carbohydrate Therapeutics -Thio-Disaccharides and their branch-chain analogs, Potential and Biological Activity” Department of Chemistry and Pharmaceutical Sciences, National University of Argentina, Rosario, Argentina, November 11, 2005.

8. “Novel Thio-sugars as Potential Drug Candidates” Institute of Organic Chemistry, Warsaw, Poland, May 8, 2009.

9. “Flavonoids and Rare Sugars and Their thio-analogs as Potential Low Calorie Sweeteners” Department of Chemistry, University of Lisbon, Lisbon, Portugal, September 11, 2009.

10. “Thio-click functionalization of Unsaturated Sugars.” Department of Chemistry, Lodz University, Poland, July 6, 2012.

11. “New Paradigm in the Development of New Targets for Galectin-3 Inhibitors.” Department of Chemistry, Lodz University, Poland, July 19, 2013.

INVITED LECTURES AT NATIONAL MEETINGS (18) 1. “(1-4)-Thiodisaccharides as Fucosidase Inhibitors” ACS Symposium on Glucosidase & Fucosidase

Inhibitors, 216th ACS National Meeting, April 1, 1998, Dallas, TX 2. “New Approaches to Stereoselective Functionalization of Levoglucosenone” ACS Symposium on

Chemicals and Materials from Renewable Resources, 218th ACS National Meeting, August 23-24, 1999, New Orleans, LA. Abstract # CARB 0xx.

3. “Synthesis of New Chiral Building Blocks from Levoglucosenone”. Z. J. Witczak, presented at 4th Annual Green Chemistry and Engineering Conference, Jun 27-29, 2000, Washington D.C. Abstract 13.

4. “New Functionalized Synthons from Levoglucosenone, Isolevoglucosenone and L-arabinose”. Z. J. Witczak, presented at 219th ACS National Meeting, March 25-30, 2000, San Francisco, CA.

5. “Thiosugars and Levoglucosenone- A Chalcone Connection 25 Years of New Perspectives”. Z. J. Witczak, Wolfrom Award Address presented at 220th ACS National Meeting, August 20-25, 2000, Washington, D.C. Abstract CARB 01.

6. “Levoglucosenone: New Chemistry and Applications: Green Chemistry Challenge” Z. J. Witczak, presented at Gordon Research Conference on Green Chemistry, Connecticut College, July 15-20, 2000, New London, CT,

7. “Carbohydrate Enones as Precursors for the Synthesis of thiodeoxy- and aminodeoxy sugars thiosugars”. Z. J. Witczak, presented at 221st ACS National Meeting, April 1-5, 2001, San Diego, CA. Abstract # CARB 0069.

8. “A New Approach to Chiral Carbohydrate Scaffolds via Stereoselective Functionalization of Levoglucosenone”. Z. J. Witczak, presented at 222th ACS National Meeting, August 26-30, 2001, Chicago, IL. Abstract # CARB 0049.

9. “From 6-Thiofructofuranose to Thiodisaccharides”. Z. J. Witczak, presented at 223rd ACS National Meeting, April 7-11, 2002, Orlando, FL. Abstract # CARB 0051.

10. “New Approach to Oligomerization/Functionalization of Levoglucosenone Dimer and Its Derivatives”. Z. J. Witczak, presented at 223rd ACS National Meeting, August 18-22, 2002, Boston, MA. Abstract # CARB 043.

11. “New Frontiers in Carbohydrate based Drug Development: Thiodisaccharides-Emerging Concept and Potential Therapeutic Applications” Z. J. Witczak, presented at Gordon Research Conference on Carbohydrates, June 22-27, 2003, Tilton, NH,

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12. “Carbohydrate-based drugs: New Developments and strategies. Z. J. Witczak, presented at 227th ACS National Meeting, March 28-April, 2004, Anaheim, CA. Abstract # CARB 0002.

13. “1,5-C-Thio-sugars as selective inhibitors of thioredoxins”. Z. J. Witczak, presented at 238th ACS National Meeting, August 16-20, 2009, Washington, D.C. Abstract # CARB 0128.

14. “Thio-click Michel addition (TCMA) approach to second generation of functionalized (1-5)-S-C-thio-oligosaccharides as anew specific inhibitors of galectin-3.” Z. J. Witczak, presented at 243th ACS National Meeting, March 25-29, 2012, San Diego, CA, Abstract # CARB 0126.

15. “Thio-enone Michel addition (TEMA) click approach to new selective inhibitors of galectin-3”. Z. J. Witczak, presented at 244th ACS National Meeting, August 19-23, 2012, Philadelphia, PA, Abstract # CARB 0065.

16. “Chiral building blocks from L-arabinose for thio-click functionalization” Z. J. Witczak, presented at 245th ACS National Meeting, April 7-11, 2013, New Orleans, LA, Abstract # CARB 0088

17. “New thio-click and domino approach to glycomimetics”. Z. J. Witczak, presented at 247th ACS National Meeting, March 16-20, 2014, Dallas, TX, Abstract # CARB 0038.

18. “Thio-click and domino approach to carbohydrate heterocycles.” Z. J. Witczak, presented at 248th ACS National Meeting, August 10-14, 2014, San Francisco, CA, Abstract # CARB 0023.

INVITED LECTURES AT NATIONAL SCIENTIFIC INSTITUTIONS (37) 1. “Synthetic Approaches to Selenosugars and their Application in Organic Synthesis,” Department of

Chemistry, Cleveland State University, Cleveland, Ohio, July 23, 1982. 2. “Synthetic Approaches to Chlorodeoxyketoses a Chlorinated Carbohydrate Sweeteners,” A. E. Staley Mfg.

Co. Research Center, Decatur, Illinois, November 15, 1986. 3. “Industrial Aspects of Synthetic Carbohydrate Chemistry: From Starches to Sugar Alcohols,” Department of

Chemistry, Creighton University, Omaha, Nebraska, March 5, 1989. 4. “Synthetic Approaches to Carbohydrate Sweeteners,” Eastman-Kodak Research Center, Kingsport,

Tennessee, June 15, 1989. 5. “Synthetic Carbohydrate Chemistry, New Challenge, and Targets for Carbohydrate Based Therapeutics,”

School of Pharmacy, University of Connecticut, July 27, 1990. 6. “Synthetic Approaches to C-Glycosides and C-Disaccharides,” Department of Medicinal Chemistry and

Pharmacognosy, University of Rhode Island, February 28, 1992. 7. “Development of High Intensity Sweeteners,” Pepsi-Cola Tech. Center, Valhalla, New York, Feb. 29, 1992. 8. “Levoglucosenone: A Versatile Precursor for the Synthesis of Natural Products,” Sloan-Kettering Cancer

Center, New York, February, 1993. 9. “Levoglucosenone: Chiral Precursor for the Synthesis of C-Di- and C-Trisaccharides and Natural Products,”

Pfizer Central Research Division, Groton, Connecticut, February 7, 1995. 10. “Levoglucosan: A Chiral Raw Material with a Wide Range of Potential Applications,” Grain Processing

Corporation Research Center, Muscatine, Iowa, July 25, 1995. 11. “New Routes to S- and C-disaccharides from Levoglucosenone,” Invited Presentation at the New Orleans

Carbohydrate Symposium, Sugar Processing Research Institute Inc., March 21th-23th, 1996, New Orleans, Louisiana.

19. “Carbohydrate Synthons- Targets for Drug Design,” Proctor & Gamble Pharmaceuticals, Miami Research Center, Cincinnati, Ohio, April 2, 1996.

20. “Synthetic Carbohydrate Antigens - New Targets and Potential Therapeutics,” School of Pharmacy, University of Connecticut, Storrs, CT, September 12, 1996.

21. “Levoglucosenone: A Convenient Precursor for the Synthesis of Complex Carbohydrates of Medicinal Interests,” Sloan-Kettering Cancer Center, New York, April 1, 1997.

22. “Cellulose, “Levoglucosan and Carbohydrate Drugs Prototypes: Dreams and Reality. Carbohydrate-based Drugs from Cellulose. Is this Possible? John S. Burlew Connecticut Valley Section of American Chemical Society Award Address. University of Connecticut, Storrs, CT, November 19, 1997.

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23. “Levoglucosan: A Convenient Chiral Precursor for the Synthesis of Value Added Products in Food Industry,” Cultor Food Science Inc. Research Center, Ardsley, NY, February, 13, 1998.

24. “Cellulose, Levoglucosenone and Carbohydrate Drugs Prototypes” Chemistry Department, Villanova University, Villanova, PA, March 17, 1998.

25. “Synthetic Analogs of Cell Surface Carbohydrates and Antigens as Potential Anticancer Agents. Dreams and Reality.” Boston Glycobiology Discussion Group, MIT, Faculty Club, Cambridge, MA, March 24, 1998.

26. “Stereoselective Approaches to S- thio and C-Disaccharides from Levoglucosenone” Department of Chemistry University of Rhode Island, September, 25, 1998.

27. “Thio-sugars Biological Relevance as New Potential Anticancer and Antimetastasis Agents” Department of Chemistry, University of Massachusetts at Dartmouth, MA, March, 3, 1999.

28. “Synthetic Thio- Analogs of Cell Surface Carbohydrates and Antigens as Potential Anticancer Agents.” Department of Pharmaceutical Chemistry, St. John’s University, Jamaica, NY, June, 3, 1999.

29. “Thio-sugars as New Potential Therapeutic Agents” School of Pharmacy, Department of Pharmaceutical Sciences, Wilkes University, Wilkes-Barre, PA, September 24, 1999.

30. “Thiodisaccharides: Biological Relevance as New Potential Therapeutics” Z. J. Witczak, presented at 219th ACS National Meeting, March 25-30, 2000, San Francisco, CA.

31. “Thiodisaccharides: New Synthetic Approaches and Importance of Sulfur Bridge for the Design of Biological Activity” Department of Chemistry, Wayne State University, Detroit, MI, October 4, 2000.

32. “Thio sugars Chemistry and Potential Therapeutic Applications” Z. J. Witczak, presented in the Department of Chemistry and Biochemistry, Florida International University, October 15, 2004, Miami, Florida.

33. “A New Paradigm for Carbohydrate Therapeutics Discovery: Non-Hydrolyzable Bioisosters of N, S-thiodisaccharides” Department of Chemistry, University of Connecticut, October 12, 2006, Storrs, Connecticut.

34. “Thio sugars as Emerging Targets for Carbohydrate Therapeutics Discovery,” Invited Presentation at the New Orleans Carbohydrate Symposium, Sugar Processing Research Institute Inc., April 12, 2008, New Orleans, Louisiana.

35. “A New Paradigm for Carbohydrate Therapeutics Discovery: Non-Hydrolyzable Bioisosters of Natural Thio Sugars” Department of Chemistry, Wayne State University, October 21, 2009, Detroit, Michigan.

36. “Thio-click functionalization of carbohydrate enones” Department of Chemistry, Binghamton University, September, 7, 2012, Binghamton, New York.

37. “Thio-click and domino functionalization of carbohydrate enones” Department of Chemistry, University of Toledo, September, 16, 2013, Toledo, Ohio.

LIST OF SELECTED PUBLICATIONS

Google Scholar Total Citation 1735, h-index 24 BOOKS (8) 1. Levoglucosenone and Levoglucosans: Chemistry and Applications, Edited by Z. J. Witczak, ATL Press,

Inc. Science Publishers, Mount Prospect, Illinois, 1994. 2. Carbohydrates in Drug Design, Edited by Z. J. Witczak and K. A. Nieforth, Marcel Dekker Inc. New

York, 1997 3. Carbohydrates Synthons in Natural Products Synthesis, Edited by Z. J. Witczak and K. Tatsuta, Oxford

University Press/ACS, Symposium Series # 841, Washington D.C., 2002 4. Carbohydrate Drug Design, Edited by A. Klyosov, Z. J. Witczak, and D. Platt Oxford University

Press/ACS, Symposium Series # 932, Washington D.C., 2006. 5. Galectins, Edited by A. Klyosov, Z. J. Witczak and D. Platt, John Wiley & Sons, New York, 2008 6. Click Chemistry in Glycoscience: New Development and Strategies, Edited by Z. J. Witczak and R.

Bielski, John Wiley & Sons, New York, 2013 7. Domino and Rearrangement Reaction in Carbohydrate Chemistry: New Development and Strategies in

Glycoscience, Edited by Z. J. Witczak and R. Bielski, John Wiley & Sons, New York, 2016

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8. Strategies for Coupling and Decoupling Molecular units in Glycoscience, Edited by Z. J. Witczak, R. Bielski, Springer, Heidelberg, 2017.

BOOKS CHAPTERS (28) 9. “Structure and Antitumor Activity of Polysaccharides,” Z. J. Witczak and R.L. Whistler, in Industrial

Polysaccharides: The Impact of Biotechnology and Advanced Methodologies, Ed. by S. S. Strivala, V. Crescenzi, and I.C.M. Dea, Gordon and Breach, N.Y., pg. 157-173, 1987.

10. “Selenium And Tellurium Derivatives of Carbohydrates and Nucleoside Analogs,” Z. J. Witczak in The Chemistry of Organic Selenium and Tellurium Compounds, S. Patai, Ed., Vol. II, pg. 756-793, John Wiley & Sons, New York, 1987.

11. “Recent Developments in Modern Synthetic Carbohydrate Chemistry,” Z. J. Witczak, in Studies in Natural Products Chemistry, Vol. III, Ed. by HEJ Atta-ur-Rahman, Elsevier: Amsterdam, pg. 209-232, 1989.

12. “Levoglucosenone: A Versatile Carbohydrate Precursor for the Synthesis of Natural Products,” Z. J. Witczak in Studies in Natural Products Chemistry, Vol. XIV, Ed. by Atta-ur-Rahman, Elsevier, Amsterdam, pg.267-282, 1994.

13. “Stereoselective Protection of Levoglucosan Derivatives” Z. J. Witczak in Levoglucosenone and Levoglucosans: Chemistry and Application, ATL Press, Inc. Science Publishers, Mount Prospect, Illinois, U.S.A. pg. 3-17, 1994.

14. “Levoglucosenone: Past, Present and Further Applications,” Z. J. Witczak in Levoglucosenone and Levoglucosans: Chemistry and Application" ATL Press, Inc. Science Publishers, Mount Prospect, Illinois, U.S.A. pg. 128-144, 1994. 61 Citations

15. “Carbohydrates: New and Old Targets for Rational Drug Design” Z. J. Witczak in Carbohydrates in Drug Design, Marcel Dekker Inc., New York, pg. 1-37, 1997.

16. “Levoglucosenone: Chiral Building Block with New Perspectives” Z. J. Witczak, In Chemicals and Materials from Renewable Resources, J. J. Bozell, Ed. ACS Books Washington D.C. pg.81-97, 2001.

17. “Monosaccharides Physical and Chemical Properties” Z. J. Witczak Chapter 4.2 in Glycoscience Chemistry and Chemical Biology, Springer, Heidelberg, pg.885-906, 2001.

18. “Di- and Oligosaccharides Physical and Chemical Properties” Z. J. Witczak Chapter 6.2 in Glycoscience Chemistry and Chemical Biology, Springer, Heidelberg, pg.1445-1461, 2001.

19. “Polysaccharides Physical and Chemical Properties” Z. J. Witczak Chapter 6.2 in Glycoscience Chemistry and Chemical Biology, Springer, Heidelberg, pg.1883-1894, 2001.

20. “Chiral Building Blocks with a New Perspectives, Revisited” Z. J. Witczak, in “Carbohydrate Synthons in Natural Products Chemistry, Synthesis Functionalization and Applications” Edited by Z. J Witczak, K. Tatsuta, Oxford University Press/ACS, Symposium Series # 841, Washington D.C. pg. 4-23, 2003.

21. “Carbohydrate Therapeutics: New Developments and Strategies”. Z. J. Witczak, in “Carbohydrate Drug Design” Edited by A. Klyosov, D. Platt and Z. J. Witczak, Oxford University Press/ACS, Symposium Series # 932, Washington D.C. pg. 4-26, 2006.

22. “New Stereoselective Functionalization of Cellulose-derived Pyrolysis Derivatives: Levoglucosenone and its Dimer” Z. J. Witczak, In “ Edited by D. Argyropoulos, Oxford University Press/ACS, Symposium Series # 954, Washington D.C. pg. 332-349, 2006.

23. “New Glycosyl Thio-carboamino Peptides as New Tools for Glycobiology” Z. J. Witczak, In “Chemical Glycobiology” Edited by C. Chen, Oxford University Press/ACS, Symposium Series # 990, Washington D.C. pg. 62-78, 2008.

24. “Monosaccharides: Occurrence, Significance and Properties” Z. J. Witczak Chapter 19 in Glycoscience Chemistry and Chemical Biology II Edition, Springer, Heidelberg, pg. 815-840, 2008.

25. “Oligosaccharides: Occurrence, Significance and Properties” Z. J. Witczak Chapter 26 in Glycoscience Chemistry and Chemical Biology II edition, Springer, Heidelberg, pp.1143-1162, 2008.

26. “Recent Advances in the Synthesis of Functionalized Carbohydrate Azides” Z. J. Witczak, Royal Chemical Society. Report, Vol. 36, 176-193, 2010. 5 Citations,

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27. “Paradigm and Advantage of Carbohydrate Click Chemistry Strategy for Future Decoupling” R. Bielski, Z. J. Witczak, in “Click Chemistry in Glycoscience: New Developments and Strategies” Edited by Z. J. Witczak, R. Bielski, John Wiley & Sons, New York, pg. 3-30, 2013.

28. “Thio-Click Chemistry Overview and Perspectives” Z. J. Witczak, in “Click Chemistry in Glycoscience: New Developments and Strategies” Edited by Z. J. Witczak, R. Bielski, John Wiley & Sons, New York, pg. 33-43, 2013.

29. “Pederin, Psymberin and the Structurally Related Mycalamides: Synthetic Aspects and Biological Activities” Z. J. Witczak, A. Bommareddy, A. L. VanWert, in “Handbook of Anticancer Drugs from Marine Origin” Edited by Se-Kwon Kim, Springer, Heidelberg, pg. 683-700, 2015.

30. “Thio-Click and Domino Approach to Carbohydrate Heterocycles” Z. J. Witczak, R. Bielski, in “Domino and Rearrangement Reactions in Carbohydrate Chemistry: New Developments and Strategies in Glycoscience” Edited by Z. J. Witczak, R. Bielski, John Wiley & Sons, New York, pg. 114-120, 2016.

31. “Introduction to Rearrangement Reactions in Carbohydrate Chemistry” Z. J. Witczak, R. Bielski, in “Domino and Rearrangement Reactions in Carbohydrate Chemistry: New Developments and Strategies in Glycoscience” Edited by Z. J. Witczak, R. Bielski, John Wiley & Sons, New York, pg. 209-218, 2016.

32. “Novel Levoglucosenone derivatives” Z. J. Witczak, R. Bielski, in “Domino and Rearrangement Reactions in Carbohydrate Chemistry: New Developments and Strategies in Glycoscience” Edited by Z. J. Witczak, R. Bielski, John Wiley & Sons, New York, pg. 240-247, 2016.

33. “Organosulfur Compounds Derived from Allium Vegetables in Cancer Prevention and Therapy” A. Bommareddy, A. L. VanWert, D.F. McCune, S. L. Brozena, Z. J. Witczak, S.V. Singh in “Critical Dietary Factors in Cancer Chemoprevention” Edited by M. F. Ullah, A. Ahmad, Springer, Heidelberg, pg. 111-153, 2016.

34. “Recent examples of novel synthetic approaches to diverse amino-sugars” Z. J. Witczak, R. Bielski, in Royal Chemical Society. Report, Carbohydr.Chem. 42, 344-367, 2017

35. “Sequential thiols recognition in coupling of functionalized carbohydrates” Z. J. Witczak, R. Bielski, in “ “Strategies for Coupling and Decoupling Molecular Units in Glycoscience” Edited by Z. J. Witczak, R. Bielski, Springer, Heidelberg, pg. xx-xx, 2017.

36. Sacrificial units in coupling and decoupling (CAD) of diverse molecules” R. Bielski, Z. J. Witczak, in “ “Strategies for coupling and decoupling Molecular units in Glycoscience” Edited by Z. J. Witczak, R. Bielski, Springer, Heidelberg, pg. xx-xx, 2017.

PUBLISHED AND ACCEPTED ARTICLES 37. “Reaction of 2'-Hydroxy-4-methoxychalcone with Hydroxylamine,” M. Krolikowska and Z. Witczak,

Roczniki Chem., 50, 1205-1208, 1976. 2 Citations, IF 0.444 38. “Reaction of 2'-Hydroxy-4-methylchalcone with Hydroxylamine,” M. Krolikowska and Z. Witczak,

Roczniki Chem., 51, 611-615, 1977. 2 Citations, IF 0.444 39. “Chalcone Oximes, Part III, The Beckman Rearrangement of 2'-Hydroxychalcone Oxime,” Z. Witczak

and M. Krolikowska, Polish J. Chem., 52, 2479-2482, 1978. 3 Citations, IF 0.444 40. “Chalcone Oximes, Part IV, Studies of the Beckman Rearrangement, New Synthesis of 2-

Styrylbenzoxazoles,” Z. Witczak M. Krolikowska, Polish J. Chem., 53, 1033-1047, 1979. 1 Citation, IF 0.444

41. “Synthesis of 4'-Amidoximeflavones,” Z. Witczak M. Krolikowska, Acta Poloniae Pharmaceutica, 37, 591-593, 1980.

42. “Chalcone Oximes, Part V, Reaction of Hydroxylamine with 4-Substituted 2-Hydroxychalcones,” Z. Witczak M. Krolikowska, Polish J. Chem., 55, 89-100, 1981. 1 Citation, IF 0.444

43. “Chalcone Oximes, Part VI, Novel Rearrangement of 2,3-Dihydro-Benzo-γ-Pyrone Oximes into Δ2 -Isoxazoline Derivatives,” Z. Witczak, Heterocycles, 14, 1319-1323, 1980. 1 Citation, IF 0.951

44. “Reaction of Hydroxylamine with 4'-Substituted Flavone Derivatives,” Z. Witczak M. Krolikowska, Polish J. Chem., 55, 763-773, 1981. X Citations, IF 0.444

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45. “2,3-Dihydro-Benzo-γ-Pyrone Oximes, Part VII, A Simple Method of Differentiation of Isomeric Derivatives of Δ2-Isoxazoline and Flavanone Oxime, A Correction of Some Structures,” Z.J. Witczak, Heterocycles, 19, 551-558, 1982. DOI: 10.3987/R-1982-03-0551 X Citations, IF 0.951

46. “A Convenient Synthesis of 3-Deoxy-D-erythro-Pentose,” Z. J. Witczak and R.L. Whistler, Carbohydr. Res., 110, 326-329, 1982. 8 Citations, IF 2.040

47. “Carbohydrates Containing Selenium" by Z. J. Witczak and R.L. Whistler, Heterocycles, 19, 1719-1734, 1982. 17 Citations, IF 0.951

48. “Monosaccharides with Phosphorus in the Sugar Ring" by Z. J. Witczak and R.L.Whistler, J. Carbohydr. Chem., 2, 351-371, 1983. 10 Citations, IF 0.847

49. “Synthesis and Preparative Applications of Monosaccharide Thiocyanates,” Z. J. Witczak, Heterocycles, 20, 1435-1448, 1983. DOI: 10.3987/R-1983-07-1435 1 Citation IF 0.951

50. “Nucleosides Containing Selenium II,” Z. J. Witczak, Nucleosides and Nucleotides, 2, 295-318, 1983. 8 Citations, IF 0.713

51. “Synthesis of 3-C-(Hydroxymethyl)-Erythritol and 3-C-Methylerythritol,” Z. J. Witczak, R. L. Whistler, and J. R. Daniel, Carbohydr. Res., 133, 235-246, 1984. 10 Citations, IF 2.040

52. “Monosaccharide Isocyanides, Synthesis, Chemistry and Application,” Z. J. Witczak, J. Carbohydr.Chem.,3, 359-380, 1984. 12 Citations, IF 0.847

53. “An Approach to a New Class of Selenosugars, A Convenient Synthesis of Glycosyl Isoselenocyanates,” Z. J. Witczak, Tetrahedron, 41, 4781-4785, 1985. 18 Citations, IF 2.899

54. “Nuclear Magnetic Resonance Determination of the Site of Acylation of the Tautomeric Nucleophile 4- Thioxopyridine,” F. Jordan, Z. Kudzin, Z. J. Witczak, and P. Hoops, J. Org. Chem., 51, 571-573, 1986. 13 Citations, IF 4.564

55. “Desulfurization of Glycosyl Isothiocyanates with Tributyltin Hydride,” Z. J. Witczak, Tetrahedron Lett. 155-158, 1986. 29 Citations, IF 2.397

56. “Synthesis of Some Derivatives of 6-Amino-1, 5-anhydro-6-deoxy-D-glucitol and 2-amino-1, 5-anhydro-2-deoxy-D-glucitol,” Z. J. Witczak and R.L. Whistler, Carbohydr. Res., 150, 121-131, 1986. 2 Citations, IF 2.040

57. “Monosaccharides Thio- and Isothiocyanates Synthesis, Chemistry and Preparative Application,” Z. J. Witczak, Adv. Carbohydr. Chem. Biochem., 44, 91-145, 1986. 70 Citations, IF 7.643

58. “Branched-Chain Alditols, A Convenient Synthesis of 6-Deoxy-2-C-Methyl-D-Mannitol and 2-C-(Hydroxymethyl)-D-Mannitol,” Z. J. Witczak and R. L. Whistler, Carbohydr. Res., 162, 252-257, 1987. 3 Citations, IF 2.040

59. “Synthesis of C-glycosyl Compounds and Other Natural Products from Levoglucosenone,” Z. J. Witczak Pure and Appl.Chem. 66, 2189-2192, 1994. 33 Citations, IF 3.386

60. “Carbohydrates as Drugs and Potential Therapeutics,” Z. J. Witczak, Current Med. Chem., 2, 392-405, 1995. 59 Citations, IF 4.471

61. “New Stereoselective Approach to (-)-(δ)-Multistriatin,” Z. J. Witczak, and Y. Li, Tetrahedron Lett.36, 2595-2598, 1995. 29 Citations, IF 2.397

62. “Synthesis of L-Fucopyranosyl-4-S-Thiodisaccharides from Levoglucosenone and Their Inhibitory Activity on L-Fucosidase,” Z. J. Witczak, J. Sun, R. Mielguj, Bioorganic & Med. Chem. Lett., 5, 2169-2175, 1995. 63 Citations, IF 2.427

63. “A Convenient Synthesis of (+) Enantiomer of Levoglucosenone and Its 5-Hydroxymethyl Analog,” Z. J. Witczak, R. Mielguj, Synlett. 108-110, 1996. 9 Citations, IF 2.655

64. “Thio-sugars II. The Novel Approach to Thiodisaccharides. The Synthesis of 3-deoxy-4-thiocellobiose from Levoglucosenone,” Z. J. Witczak, R. Chhabra, H. Chen, X-Q. Xie, Carbohydr.Res.301, 167-175, 1997. 73 Citations, IF 2.040

65. “C-Disaccharides I. Stereoselective Approach to β-(1-4)-3-Deoxy-C-Disaccharides from Levoglucosenone,” Z. J. Witczak, R. Chhabra, J. Chojnacki, Tetrahedron Lett., 38, 2215-2218, 1997. 43 Citations, IF 2.397

66. “Synthetic Application of Selenium-Containing Sugars,” Z. J. Witczak and S. Czernecki, Adv.Carb.Chem. Biochem. 53, pg.143-199, 1998. 26 Citations, IF 7.643

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67. “Thio-sugars IV. Design and Synthesis of S-Linked Fucoside Analogs as New Class of α-L-Fucosidase Inhibitors” Z. J. Witczak, D. Boryczewski, Bioorganic & Med. Chem. Lett., 8, 3265-3268, 1998. 24 Citations, IF 2.427

68. “Thio-sugars: Biological Relevance as New Potential Therapeutics” Z. J. Witczak, Current Med. Chem., 6, 159-172, 1999. 106 Citations, IF 4.471

69. “Thio-sugars III. Stereoselective Approach to β-(1,2)-2,3-Dideoxy-2-C-acetamidomethyl-2-S-thiodisaccharides from Levoglucosenone Z. J. Witczak, R. Chhabra, D. Boryczewski, J.Carb.Chem.19, 543-553, 2000. 15 Citations, IF 0.847

70. “Thio-sugars V. From D-Glucal to 3-deoxy-(1-2')-2-S-thiodisaccharides through Isolevoglucosenone- a Simple Approach.,” Z. J. Witczak, H. Chen, and P. Kaplon, Tetrahedron: Asymmetry, 11, 519-532, 2000. 27 Citations, IF 2.143

71. “Synthesis and Biological Properties of Monothiosaccharides” I. Robina, P. Vogel, Witczak Z. J. Curr. Org. Chem., 5, 1177-1214, 2001. 55 Citations, IF 3.222

72. “A New Approach to Isolevoglucosenone via 2, 3-Sigmatropic Rearrangement of an Allylic Selenide” Z. J. Witczak, P. Kaplon, M. Kolodziej. J. Carbohydr. Chem., 21, 143-148, 2002. 7 Citations, IF 0.847

73. “Thio-sugars VI. A Simple Stereoselective Approach to (1-3)-3-S-Thiodisaccharides from Levoglucosenone,” Z. J. Witczak, P. Kaplon, M. Kolodziej, Monatshefte fur Chemie, 20, 521-530, 2002. Citations, IF 2.040

74. “Thio-sugars VII. Effects of α-(1-4)-3’deoxythiodisaccharides and Their Sulfoxides and Sulfones on the Viability and Growth of Selected Murine and Human Tumor Cell Line” Z. J. Witczak, P. Kaplan. P. M. Dey, Carbohydr. Res., 338, 11-18, 2003. 33 Citations, IF 2.040

75. “Functionalized S-Thio-di- and S-Oligosaccharide Precursors as Templates for Novel SLex/a Mimetics Antimetastatic Agents.” P. M. Dey, Z. J. Witczak, Mini Review in Medicinal Chemistry. 3, 257-261, 2003. 23 Citations, IF 2.921

76. “Thio-sugars; New Perspectives Regarding Availability and Potential Biochemical and Medicinal applications” Z. J. Witczak, J.M. Culhane, Appl. Microbiol. & Biotech, 69, 237-244, 2005. 79 Citations, IF 3.613

77. “Click chemistry approach to glycomimetics. Michael addition of 1-β-thioglucose to 4,6-dideoxy-1, 2-O-isopropylidene-D-glycero-pent-4-enopyranos-3-ulose. A convenient route to novel 4-deoxy-(1→5)-5-C-thiodisaccharides.” Z. J. Witczak, D. Lorchak, N. Nguyen, Carbohydr. Res., 342, 1929-1931, 2007. 30 citations, IF 2.040

78. “New Strategies and Targets in the Development of Carbohydrate Therapeutics”. Witczak Z.J., Chemistry Today, 25, (4), 86-90, 2007. 1 citation, IF 0.539

79. “Mycalamides, Pederin and Psymberin as Natural Carbohydrates and Potential Antitumor Agents: Past and Future Perspectives” Z. J. Witczak, R. M. Rampulla, A. Bommareddy, Mini Review in Medicinal Chemistry, 12, (14), 1520-1532, 2012. 5 Citations, IF 2.921

80. “Thio-click Approach to Glycomimetics” Z. J. Witczak, Phosporus, Sulfur & Silicon and the related Elements, 188, 237-244, 2012. 4 citations, IF 0.716

81. “Strategies of Coupling Molecular Units when later Decoupling is needed” R. Bielski, Z. J. Witczak, Chem. Rev, 113, 2205-2243, 2013. DOI: 10.1021/cr200338q. 19 Citation, IF 41.298

82. “Prostate cancer chemoprevention by major dietary phytochemicals: A minireview”. A. Bommareddy*, W. Eggleston, S. Prelewicz, A. Antal, Z. J. Witczak, D. F. McCune and A. L. VanWert, Anticancer Res., 33, 4163-4174, 2013. 36 citations, IF 1.725

83. “A Potential CARB-pharmacophore for antineoplastic activity. Part I.” Z. J. Witczak, T. Poplawski A. Czubatka, J. Sarnik, P. Tokarz, A. L. VanWert, R. Bielski, Bioorganic & Med. Chem. Lett., 2014, 24, 1752-1757, 4 citations IF 2.338.

84. “Thio-sugar motif of functional CARB-pharmacophore for antineoplastic activity. Part II. Z. J. Witczak, J. Sarnik, A. Czubatka, T. Poplawski, Bioorganic & Med. Chem. Lett., 2014, 24, 5606-5611, 1 citation IF 2.338.

85. “New Developments in the synthesis of deoxy- and branched-chain sugars” R. Bielski, Z. J. Witczak, Current Org Chem. 2014, 18, (14) 1897-1912, 4 citations, IF 3.222

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86. “A novel carbohydrate derived compound FCP5 causes DNA strand breaks and oxidative modifications of DNA bases in cancer cells”. A. Czubatka, J. Sarnik, D. Lucent, Z. J. Witczak, T. Poplawski, Chemico-Biological Interaction., 2015, 227, 77-88, 3 citations, IF 2.967.

87. “Hetero Oxa-Claisen Rearrangement: Perspective on New Synthetic Pathways and Structures” R. Bielski, Z. J. Witczak, Current Organic Synthesis, 2016, 13, 750-760.

88. “Tiocukry jako Leki” J. Sarnik, A. Czubatka-Bienkowska, J. Dziadek, Z. J. Witczak, T. Poplawski, Postepy Biochemii, 2016, 62, (4) 1-9.

89. “The oxidative induction of DNA lesions in cancer cells by 5-thio-D-glucose and 6-thio-D-fructopyranose and their genotoxic effects. Part 3.” J. Sarnik, A. Czubatka-Bienkowska, A. Macieja, Z. J. Witczak, T. Poplawski, Bioorganic & Med. Chem. Lett., 2017, 27, 1210-1214.

90. “The induction of oxidative stress in cervix carcinoma by levoglucosenone derived 4-S-salicyl derivative and (1-4)-S-thiodisaccharides”. Part 4. J. Sarnik, A. Czubatka-Bienkowska, A. Macieja, R. Bielski, Z. J. Witczak, T. Poplawski, Bioorganic & Med. Chem. Lett., 2017, 27, 1215-1219.

91. “Evaluation of the Mycobactericidal Effect of Thio-functionalized Carbohydrate Derivatives”. M. Korycka, Machala, A. Brzostek, B. Dziadek, M. Kawka, T. Poplawski, Z. J. Witczak, J. Dziadek, Molecules, 2017, 22, 812-827.

92. “Thio-functionalized thiosemicarbazones and their evaluation of anticancer activity”. A. Czubatka-Bienkowska, J. Sarnik, A. Macieja, G. Galita, Z. J. Witczak, T. Poplawski, Bioorganic & Med. Chem. Lett., 2017, 27, 2713-2720.

93. “Carbohydrate exo-cyclic enones. Part I. Direct Aldol Condensation of Dihydrolevoglucosenone and Five-membered Heterocyclic Aldehydes: Stereoselective formation of E-isomers of exo-cyclic Carbohydrate Enones” Z. J. Witczak, R. Bielski, D. Mencer, Tetrahedron Lett., 2017, 58, 4089-4073.

94. “Carbohydrate exo-cyclic enones. Part II. Direct Aldol Condensation of Dihydrolevoglucosenone and Aromatic Aldehydes: Stereoselective formation of E-isomers of exo-cyclic Carbohydrate Enones” R. Hohol, H Arcure Z. J. Witczak, R. Bielski, D. Mencer, Org. Lett., 2017, In press.

95. “Drug Delivery as it should be: Chemist’s perspective” R. Bielski, Z. J. Witczak, Nature Review Drug Discovery, 2017, In press.

BOOKS REVIEWS (17) 1. “Gums and Stabilizers for the Food Industry,” Vol. III, Ed. by G.O. Philips, Elsevier Appl. Sci. Publishers,

London, 1986. Book Review: Z. J. Witczak Carbohydr. Res., 155, C11, 1986. 2. “Selenium in Natural Product Synthesis,” K.C. Nicolaou and N.A. Petasis, CIS, Inc. Philadelphia, 1984.

Book Review: Z. J. Witczak, J. Med. Chem., 28, 1967, 1986. 3. “Cellulose Hydrolysis,” L.T. Fan, M.M. Gharpuray, Y.H. Lee, Springer-Verlag, Berlin, Heidelberg, 1987.

Book Review: Z. J. Witczak, J. Am. Chem. Soc., 109, 625, 1987. 4. “Carbohydrate Chemistry,” Vol. 17, Ed, by N.R. Williams, R.S.C. London 1985, Book Review: Z. J.

Witczak, J. Am. Chem. Soc., 109, 625, 1987. 5. “Starch: Properties and Potential. Critical Reports on Applied Chemistry,” Vol. 13, Ed. by T. Galliard, John

Wiley & Sons: New York, 1987. Book Review: Z. J. Witczak, J.Am.Chem.Soc. 111, 797, 1989. 6. “Synthetic Oligosaccharides Indispensable Probes for the Life Sciences,” P. Kovac, Ed., ACS Symposium

Series No. 560, ACS Washington, D.C., 1994. Book Review: Z. J. Witczak, J. Carbohydr. Chem., 14, 271, 1995.

7. “Monosaccharides: Their Chemistry and Their Roles in Natural Products,” P. Collins and R. Ferrier, John Wiley & Sons, Inc., New York, 1995. Book Review: Z. J. Witczak, J. Nat. Products, 58, 1797, 1995.

8. “C-Glycoside Synthesis,” M.H.D. Postema, CRC Press, Inc, Boca Raton. 1995. Book Review by Z. J. Witczak, J.Carbohydr.Chem. 14, 1692, 1995.

9. “The Chemistry of C-Glycosides,” D. E. Levy and C. Tang, Pergamon-Elsevier Science Ltd. Oxford, 1995. Book Review: Z. J. Witczak, J.Carbohydr. Chem., 15, 651, 1996.

10. “Enediyne Antibiotics as Antitumor Agents,” T. Borders and T. Doyle, Eds., Marcel Dekker Inc., New York, 1995. Book Review: Z. J. Witczak, J.Carbohydr. Chem., 15, 649, 1996.

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11. “Polysaccharides in Medicinal Applications,” S. Dumitriu, Ed., Marcel Dekker Inc. New York, 1995. Book Review: Z. J. Witczak, J.Carbohydr. Chem., 16, 245, 1997.

12. “Modern Methods in Carbohydrate Synthesis,” S. H. Khan and R. O’Neill Eds., Harwood Academic Publishers, Amsterdam, 1996. Book Review: Z. J. Witczak, J.Carbohydr. Chem., 16, 715, 1997.

13. “Carbohydrates Structure and Biology” by Jochen Lehmann, Translated by Alan H. Haines, Thieme, New York, 1998. Book Review Z. J. Witczak, Synthesis, 1390, 1998.

14. “Monosaccharide Sugars Chemical Synthesis by Chain Elongation, Degradation and Epimerization” Z. Györgydeák and I. F. Pelyvás, Academic Press, San Diego, 1998. Book Review: Z. J. Witczak, J. Nat. Products, 61, 1317, 1998.

15. “Glycopeptides and Related Compounds. Synthesis, Analysis and Applications” D. G. Large, and C. D. Warren, Eds., Marcel Dekker, New York, 1999. Book Review Z. J. Witczak, J. Carbohydr. Chem., 18, 116-118, 1999.

16. “Analytical Chemistry of Carbohydrates” by H. Scherz, and G. Bonn, Thieme, New York, 1998. Book Review Z. J. Witczak, J. Carbohydr. Chem., 18, 478, 1999.

17. “Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries” by P.H. Seeberger, Wiley-Interscience, New York, 2001. Book Review Z. J. Witczak, J. Carbohydr. Chem., 21, 178, 2002.

MEETING NEWS REPORTS (9)

1. “Glucosidase and Fucosidase Inhibitors” & “Advances in Nucleosides and Nucleotides” Meeting Report, 215th ACS, Z. J. Witczak, IDrugs, 1, 1, 30-31, 1998.

2. “Glucosidase and Fucosidase Inhibitors” & “Advances in Nucleosides and Nucleotides” Symposiums at 215th American Chemical Society Meeting, Dallas, TX, Meeting News Report, Z. J. Witczak Current Drugs, 4, 39-41, 1998.

3. “Recent Developments in Oligonucleotide Therapeutics” & “Anthracyclines from bench to the clinic” Symposiums at 217th American Chemical Society Meeting, Anaheim, CA, Meeting News Report, Z. J. Witczak Current Drugs, 5, 39-41, 1999.

4. “Carbohydrate Vaccines” & “Advances in Nucleosides and Oligonucleotides” Symposiums at 218th American Chemical Society Meeting, New Orleans, LA, Meeting News Report, Z. J. Witczak, ID weekly highlights, 9, 30-32, 1999.

5. “First Euroconference on Carbohydrates in Drug Research (ECCDRI)”Stintino, Sardinia, Italy, Meeting News Report, Z. J. Witczak, ID weekly highlights, 10, 38-41, 1999.

6. “Oligonucleotide Therapeutics” & “Carbohydrate Therapeutics” Symposiums at 219th American Chemical Society Meeting, San Francisco, CA, Meeting News Report, Z. J. Witczak, ID weekly highlights, 11, 50-51, 2000.

7. “Inosine Monophosphate Dehydrogenase (IMPDH) Perspectives on Major Therapeutic Target” Symposium at 220th American Chemical Society, Washington D.C. Meeting News Report, Z.J. Witczak, ID Drugs ,4, 1283-1284 2000.

8. “Nucleic Acid Based Therapeutics and Related Technologies” Symposium at 221th American Chemical Society, San Diego, CA. Meeting News Report, Z. J. Witczak, ID weekly highlights, 12, 60-62, 2001.

9. “Carbohydrate Therapeutics” Symposiums at 223rd American Chemical Society Meeting, Orlando, FL, Meeting News Report, Z. J. Witczak, ID weekly highlights, 12, 50-51, 2002.

PAPERS PRESENTED AT MEETINGS AND SYMPOSIUMS (126) 1. “Reaction of 4'-Cyanoflavones with Hydroxylamine,” Z. J. Witczak, M. Krolikowska, presented at the XI

Scientific Meeting of the Polish Pharmaceutical Association, 17 - 19 September 1979, Gdansk, Poland. 2. “Reaction of Hydroxylamine with ω-Thiocyanatoacetophenone,” Z. J. Witczak, presented at the XXX

Scientific Meeting of the Polish Chemical Society, 12 -15 September 1981, Gdansk, Poland. Abstract # 3. “The Preparation and Chemical Transformation of Glucopyranosyl Selenocyanates,” Z. J. Witczak,

presented at the X International Meeting of Heterocyclic Chemistry, 8-12 August 1985, Waterloo, Canada. Abstract #

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4. “Relative Sweeteners of Several Chlorodexy Ketoses,” Z. J. Witczak, J. R. Daniel, and R. L. Whistler, presented at the 190th American Chemical Society Meeting, 9-13 September 1985, Chicago, U.S.A. Abstract #

5. “1,4-Anhydro and 1,4-3,6-Dianhydro-α-D-Glucopyranoses; Isolation, Synthetic and Structural Study,” Z. J. Witczak, presented at the XV International Carbohydrate Symposium-Yokohama, Fuji 90, Post-Symposium, 18 - 21 August 1990, Susono City, Japan. Abstract #

6. “A Concise Approach to C-Sucrose and C-Isosucrose,”Z. J. Witczak, presented at the 203rd American Chemical Society Meeting in San Francisco, California, April 5-10, 1992. Abstract #

7. “Synthesis of New Carbohydrate Analogs of (+)-Hernandulcin,” Z. J. Witczak, presented at the IUPAC XVI International Carbohydrate Symposium, 5-10 July 1992, Paris, France. Abstract # 115

8. “The Synthesis of Carbocyclic Analog of Levoglucosenone,” Z. J. Witczak, presented at the 204th American Chemical Society Meeting in Washington D.C., August 23-28, 1992. Abstract #

9. “The Synthesis of C-Trisaccharide from Levoglucosenone,” Z. J. Witczak, presented at 205th American Chemical Society Meeting in Denver, Colorado, March 25-31, 1993. Abstract #

10. “A New Sucrose Synthons for C-C Coupling,” Z. J. Witczak, presented at the 205th American Chemical Society Meeting in Denver, Colorado, March 25-31, 1993. Abstract #

11. “Synthesis of C-Disaccharides from Levoglucosenone,” Z. J. Witczak, presented at the VIIth European Carbohydrate Symposium, August 22-28, 1993, Cracow, Poland. Abstract # A103.

12. “Synthesis of C-Glycosyl Compounds and other Natural Products from Levoglucosenone,” Z. J. Witczak, presented at the 19th IUPAC Symposium on Natural Products, January 16 -20 1994, Karachi, Pakistan. Abstract #

13. “A New Carbohydrate Analogues of (+)-Hernandulcin,” Z. J. Witczak, presented at the 19th IUPAC Symposium on Chemistry of Natural Products, January 16-20, 1994, Karachi, Pakistan. Abstract #

14. “Synthesis of (+) Levoglucosenone and its Applications,” Z. J. Witczak, presented at the 207th American Chemical Society Meeting in San Diego, California, March 13-18, 1994. Abstract #

15. “Synthesis of Carba-2-Deoxysucrose Derivatives: Potential Inhibitors of α-Glucofuranosidase,” Z. J. Witczak, and J. Sun, presented at the 207th American Chemical Society Meeting in San Diego, California, March 13-18, 1994. Abstract #

16. “Synthesis of C-Trisaccharide Analogues of Sialyl Lewisx from Levoglucosenone,” Z. J. Witczak, presented at XVIIth International Carbohydrate Symposium, July 17- 22, 1994, Ottawa, Canada. Abstract #

17. “A Convenient Synthesis of (-)-δ-Multistriatin from Levoglucosenone,” Z. J. Witczak, presented at International Research Congress on Natural Products, July 31-August 4, 1994, Halifax, Nova Scotia, Canada. Abstract #

18. “New Analogs of Sucrose,” J. Sun and Z. J. Witczak, presented at the 208th American Chemical Society Meeting, Washington D.C. August 21-25, 1994. Abstract #

19. “C-trisaccharide of Sialyl Lewisx from Levoglucosenone,” Z. J. Witczak, J. Sun, Y. Li, presented at 208th American Chemical Society Meeting, Washington D.C. August 21-25, 1994. Abstract #

20. “New Routes to Glycosyl Nitromethanes from Aldonolactones,” Z. J. Witczak, Y. Li, I. Fokt, T. Przewloka, W. Priebe, presented at 209th American Chemical Society Meeting, Anaheim, CA, April 2nd -7th, 1995. Abstract #

21. “New Routes to Sugar Thio- and Isothiocyanates and Thiosugars from Levoglucosenone,” Z. J. Witczak, presented at 209th American Chemical Society Meeting, Anaheim, CA, April 2 - 7, 1995. Abstract #

22. “Inhibitory Effects of Epstein-Barr Virus Activation and Anti-tumor Promoting Activities of Synthetic Flavonoids,” Z. J. Witczak, H. Tokuda, H. Nishino, presented at American Society of Pharmacognosy National Meeting, Oxford, Mississippi, July, 21-24, 1995. Abstract # A-.

23. “Leucrose as New Precursor for the Synthesis of α-Glucosidase Inhibitors,” J. Sun, Z. J. Witczak, presented at 210th American Chemical Society Meeting, Chicago, IL, August 20-24, 1995. Abstract # CARB

24. “C-Di-and C-S-Thiosaccharide analogs of Lewisx from Levoglucosenone,” Z. J. Witczak, J. Sun, Y Li, presented at Glupor I -1st International Meeting of Portuguese Carbohydrate Chemistry Group, Lisbon, Portugal, September 26-30, 1995. Abstract #

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25. “C-Trisaccharide of Sialyl Lewisx from Levoglucosenone,” Z. J. Witczak, J. Sun, presented at the 1995 International Chemical Congress of Pacific Basin Societies, December 17-22, 1995, Honolulu, Hawaii. Abstract #

26. “New Approaches to S- and N-Linked Disaccharides from Levoglucosenone and Maltol,” Z. J. Witczak, R. Chhabra, presented at 211th American Chem. Soc. Meeting, New Orleans, LA, March 24-28, 1996. Abstract #

27. “Levoglucosenone: A Convenient Synthon to S- and S-,N-linked Disaccharides,” Z. J. Witczak, presented at the 30th ACS Middle Atlantic Regional Meeting, May 22-24, 1996, Villanova University, Villanova, PA.

28. “A Convenient Synthesis of Methyl Analog of (-)-δ-Multistriatin from Sedoheptulosan,” Z. J. Witczak, R. Chhabra, J. Chojnacki, presented at Gordon Research Conference on Natural Products, June 30-July 5, 1996, Henniker, New Hampshire. Abstract #

29. “Levoglucosenone: chiral Synthon for the Synthesis of C- S- and N- Glycosides,” Z. J. Witczak, Invited lecture presentation at the XVIIIth Iupac International Carbohydrate Symposium, July 21-26, 1996, Milano, Italy. Abstract #

30. “New Approaches to mixed C-S-, and N-trisaccharide Analogs of Lewisx from Levoglucosenone,” Z. J. Witczak, R. Chhabra, J. Chojnacki, Poster Presentation at the XVIIIth Iupac International Carbohydrate Symposium, July 21-26, 1996, Milano, Italy. Abstract #

31. “(2-4)-Thioglycosides of Sialic Acid from Levoglucosenone,” Z. J. Witczak, R. Chhabra, H. Chen, presented at the 213th American Chemical Society Meeting, April 13-17, 1997, San Francisco, CA. Abstract # CARB-039.

32. “Stereoselective New Approaches to mixed C-S-, Trisaccharide Analogs of Lewisx from Levoglucosenone,” Z. J. Witczak, R. Chhabra, J. Chojnacki, D. Boryczewski, H. Chen, presented at the International Conference on Glycoconjugates and Matrix Molecules in Health & Disease, August 20-22, 1997, Bethesda, MD. Abstract #

33. “4-Azido-4-Deoxy and 4-Amino-4-deoxysugars from Levoglucosenone,” Z. J. Witczak, H. Chen, presented at the 214th American Chemical Society Meeting, September 7-11, 1997, Las Vegas, NV. Abstr, # CARB 063.

34. “Stereoselective Synthesis of C-Di-and C-,S-, and N-Glycosides of Therapeutic Potential from Levoglucosenone,” Z. J. Witczak, presented at Glupor II-2nd International Meeting of Portuguese Carbohydrate Chemistry Group, September 21-25, 1997, Porto, Portugal. Abstract #

35. “(1-4)-3-Deoxy-selenodisaccharides from Levoglucosenone”, Z. J. Witczak, R. Chhabra, H. Chen, presented at the 5th American Chemical Congress of North America, November 11-15, 1997, Cancun, Mexico.

36. “Novel Thiosugars as α-L-Fucosidase Inhibitors. Design, Synthesis and Substituent Effect on Inhibitory Activity" Z. J. Witczak, H. Chen, I. Fokt, T. Przewloka, M. Krawczyk and W. Priebe, presented at 216th ACS National Meeting, March 29-April 3, 1998, Dallas, TX. Abstract # CARB-0049.

37. “Novel Thiotrisaccharides of L-fucose as α-L-Fucosidase Inhibitors”. Z. J. Witczak, R. Chhabra, M. Klodziej, presented at 26th National Medicinal Chemistry, June 14-18, 1998, Richmond, VA. Abstract #

38. “Stereoselective New Approaches to (1-4) and (1-2)-S-Thiodisaccharides from Levoglucosenone,” Z. J. Witczak, R. Chhabra, J. Chojnacki, and P Kaplon, presented at the XXI, International Carbohydrate Symposium, August 9-14, 1998, San Diego, CA. Abstract BP122.

39. “Novel Thio derivatives of L-fucose as α-L-Fucosidase Inhibitors”, Z. J. Witczak, R. Chhabra, M. Klodziej, 216th ACS National Meeting, August 23-27, 1998, Boston, MA. Abstract # MEDI-.

40. “New Approach to S-Thiotrisaccharides from Levoglucosenone”. R. Chhabra, Z. J. Witczak, presented at 217th ACS National Meeting, March 21-25, 1999, Anaheim, CA. Abstract # CARB-049.

41. “New Stereoselective Approaches to Functionalization of Levoglucosenone” Z. J. Witczak, presented at 218th ACS National Meeting, August 22-26, 1999, New Orleans, LA. Abstract # CELL.

42. “Thiodisaccharides: Biological Relevance as New Potential Therapeutics” Z. J. Witczak, presented at 219th ACS National Meeting, March 25-30, 2000, San Francisco, CA. Abstract # CARB-0061.

43. “New Functionalized Synthons from Levoglucosenone, Isolevoglucosenone and L-arabinose”. Z. J. Witczak presented at 219th ACS National Meeting, March 25-30, 2000, San Francisco, CA. Abstract # CARB 086.

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44. “Synthesis of New Chiral Building Blocks from Levoglucosenone”. Z. J. Witczak presented at 4th Annual Green Chemistry and Engineering Conference, Jun 27-29, 2000, Washington D.C. Abstract # 49.

45. “Levoglucosenone: New Chemistry and Applications: Green Chemistry Challenge” Z. J. Witczak, presented at Gordon Research Conference on Green Chemistry, Connecticut College, July 15-20, 2000, New London, CT, Abstract #

46. “Thiosugars and Levoglucosenone a Chalcone Connection: Twenty-five Years of New Perspectives”. Z. J. Witczak, presented at 220th ACS National Meeting, August 20-25, 2000, Washington, D.C. Abstract # CARB-0001.

47. “Carbohydrate Enones as Precursors for the Synthesis of thiodeoxy- and Aminodeoxy sugars thiosugars”. Z. J. Witczak, presented at 221st ACS National Meeting, April 1-5, 2001, San Diego, CA. Abstract # CARB 0069.

48. “A New Approach to Chiral Carbohydrate Scaffolds via Stereoselective Functionalization of Levoglucosenone”. Z. J. Witczak, presented at 222th ACS National Meeting, August 26-30, 2001, Chicago, IL. Abstract # CARB-49.

49. “From 6-Thiofructofuranose to Thiodisaccharides”. Z. J. Witczak, presented at 223rd ACS National Meeting, April 7-11, 2002, Orlando, FL. Abstract # CARB-0051.

50. “New Approach to Oligomerization/Functionalization of Levoglucosenone Dimer and Its Derivatives”. Z. J. Witczak, presented at 223rd ACS National Meeting, August 18-22, 2002, Boston, MA. Abstract # CARB 043.

51. “New Thiodisaccharides as Modulators of vascular Smooth Muscle Proliferation”. J.M. Culhane, Z. J. Witczak, J. Kukel, M. Remmel, A. Soares, C. Rock, P.M. Dey, presented at 225th ACS National Meeting, March 23-27, 2003, New Orleans, LA. Abstract # CARB-032.

52. “Stereoselective New Approaches to (1-4) and (1-2)-S-Thiodisaccharides from Levoglucosenone,” Z. J. Witczak, presented at the XXII, International Carbohydrate Symposium, July 25-28, 2004, Glasgow, United Kingdom, Abstract # P-19

53. “Stereoselective Synthesis of 1, 5 S-thiodisaccharides from L-Arabinose Enones” Z. J. Witczak, D. Lorchak, presented at the 2005 MARM ACS, Rutgers University New Brunswick, NJ May 22-25, 2005. Abstract #

54. “Synthesis of C-S-thiodisaccharides from L-Arabinose and D-Galactose Nitro-enones” Z. J. Witczak, D. Lorchak, J. Danowski, J. Dwyer, presented at 230th ACS National Meeting, August 29-Sept. 1, 2005.Washington D.C. Abstract # CARB-056.

55. “A New Stereoselective Functionalization of Cellulose Derived Pyrolysis Derivatives Levoglucosenone and Its Dimer” Z. J. Witczak, presented at the Pacifichem 2005, Honolulu, Hawaii, December 15-20 2005, Abstract # AGRC-0356.

56. “Synthesis of S-C-Linked Thio-disaccharide Mimics as Potential Tools for Glycobiology” Z. J. Witczak, presented at the Pacifichem 2005, Honolulu, Hawaii, December 15-20, 2005, Abstract # GLYC-8.

57. “Stereoselective Synthesis of 1,5-S-thiodisaccharides from L-Arabinose Enones” Z. J. Witczak, presented at the 2006 MARM ACS, Hershey, PA, June 4, 2006. Abstract # CARB-219.

58. “New glycosyl carboaminopeptides as new tools for glycobiology” Z. J. Witczak, presented at 232th ACS National Meeting, September 5-29, 2006, San Francisco, CA, Abstract # CARB-69.

59. “Novel Synthetic Approach to 1,2-thiodisaccharides from 3-nitro-and 3-cyano- Carbohydrate Enones” C. Cassett, Z. J. Witczak, R. Spanevello, M.I. Mangione, A. Suarez, presented at 233th ACS National Meeting, March 25-29, 2007, Chicago, Abstract # CARB-0069.

60. “New Synthetic Approach to C-S-thiodisaccharides from C-disaccharide Enones” Z. J. Witczak, J. Danowski J. Dwyer, S. Jarosz, E. Kozlowska, presented at 233th ACS National Meeting, March 25-29, 2007, Chicago, Abstract # CARB-0068.

61. “Carbohydrate Enones. New Stereoselective Approaches to Thiosugars. 3-5- and 5,5’-S-thiodisaccharides from L-Arabinose Enone”. Z. J. Witczak, presented at 233th ACS National Meeting, March 25-29, 2007, Chicago, Abstract # CARB-0032.

62. “Exploration of functionalized carbohydrate enones to the synthesis of Tagetitoxin” Z. J. Witczak, presented at 234th ACS National Meeting, August 19-23, 2007, Boston, MA, Abstract # CARB-

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63. “Thio-sugars as Emerging Targets for Carbohydrate Therapeutics Discovery ” Z. J. Witczak, presented at 1st International Conference on Drug Design & Discovery, February 4-7, 2008, Dubai, URE, Abstract # A-157

64. “New Analogs of Thiolactomycin as Emerging Targets for Antimalarial and Antitubercular Carbohydrate Drug Discovery” Z. J. Witczak, presented at 24th International Carbohydrate Symposium, July 27-August 1, 2008, Oslo, Norway, Abstract # AO 013

65. “New Carbohydrate Synthons from L-Arabinose and their Stereoselective Functionalization” Z. J. Witczak, A. Jankowski, presented at 235th ACS National Meeting, August 17-21, 2008, Philadelphia, PA, Abstract # CARB-76.

66. “New Analogs of (1-5)-5-C-thiodisaccharides as Potential Carbohydrate Therapeutics” Z. J. Witczak, presented at 236th ACS National Meeting, March 22-26, 2009. Salt Lake City, UT, Abstract # CARB-32.

67. “Conformational and NMR Studies of (1-5)-5-C-thiodisaccharide ” H. Castejon, C. Bernecker, J. Huff, Z. J. Witczak, presented at 236th ACS National Meeting, March 22-26, 2009. Salt Lake City, UT, Abstract # CARB-33.

68. "Natural thio sugars and their bioisosteres functionalizations" Z. J. Witczak, presented at 238th ACS National Meeting, August 15-19, 2009. Washington D.C. Abstract # CARB-0003.

69. "1,5-C-Thio sugars as selective inhibitors of thioredoxins" Z. J. Witczak, presented at 238th ACS National Meeting, August 15-19, 2009. Washington D.C. Abstract # CARB-0128.

70. “Thio-sugars as Emerging Targets for Antimalarial and Antitubercular Carbohydrate Therapeutics Discovery” Z. J. Witczak, presented as Plenary Lecture at Glupor 8 International Meeting of the Portuguese Carbohydrate Group. University of Minho, Braga, Portugal, September 6-10, 2009. Abstract # PL-3

71. “Stable isosteres of thio sugar templates as the new targets for galectin-3 inhibitors” Z. J. Witczak, presented at 239th ACS National Meeting, March 21-25, 2010, San Francisco, CA, Abstract # CARB-0105.

72. “Thio-click chemistry approach to glycomimetics: Novel Stereoselective Synthesis of (1,3)-S- thiodisaccharides” I. Bak-Sypien, Z. J. Witczak, presented at 240th ACS National Meeting, August 22-26, 2010, Boston, MA, Abstract # CARB-0105.

73. “How to Marry sugar Molecules (Missaliance Included) using Click Chemistry? How to Divorce Them? R. Bielski, Z. J. Witczak, presented at 241th ACS National Meeting, March 27-30, 2011, Anaheim, CA, Abstract # CARB-0013.

74. “Thiol-click chemistry approach to glycomimetics revisited: Synthesis of multifunctional templates to new families of thio sugars” Z. J. Witczak, presented at 241th ACS National Meeting, March 27-30, 2011, Anaheim, CA, Abstract # CARB-0023.

75. “Thio-click chemistry approach to glycomimetics: Synthesis of multifunctional templates to new families of thio sugars” Z. J. Witczak, A. Jankowski Invited presentation at 16th European Carbohydrate Symposium, July 3-5, 2011, Sorrento, Italy, Abstract # AO 013

76. “Thio-click Michael Addition (TCMA) Approach to Second Generation of Functionalized (1-5)-S-C-thio-oligosaccharides as New Specific Inhibitors of Galectin-3” Z. J. Witczak, presented at 243th ACS National Meeting, March 25-29, 2012, San Diego, CA, Abstract # CARB-0126.

77. “Thio-click addition approach to glycomimetics” Z. J. Witczak, presented at 25th International Symposium on the Organic Chemistry of Sulfur (ISOCS), June 24-29, 2012, Czestochowa. Poland, Abstract # OC-A-16.

78. “Thio-click chemistry approach to glycomimetics. Synthesis and design of new thio sugars as potential inhibitors of galectin-3.” Z. J. Witczak, A. Jankowski, S. Silvi, presented at 26th International Carbohydrate Symposium, July 22-27, 2012, Madrid, Spain, Abstract # O-76

79. “Thiol-enone Michael addition (TEMA) click approach to new selective inhibitors of galectin-3.” Z. J. Witczak, presented at 244th ACS National Meeting, August 19-23, 2012, Philadelphia, PA, Abstract # CARB-0065

80. “Thio-click functionalization of 4-Deoxy-1,2-O-isopropylidene-D-glycero-pent-4-enopyranos-3-ulose” Z. J. Witczak, S. Silvi, T. Bridges, B. Dudeck, presented at 244th ACS National Meeting, August 19-23, 2012, Philadelphia, PA, Abstract # CARB-0047

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81. “Chiral building blocks from L-arabinose for thio-click functionalization” Z. J. Witczak, presented at 245th ACS National Meeting, April 7-11, 2013, New Orleans, LA, Abstract # CARB-0088.

82. “Thio-click approach to glycomimics: Design and Synthesis of novel thio-sugars as potential inhibitors of galectin-3” Z. J. Witczak, N. Patel presented at 17th European Carbohydrate Symposium, July 7-11, 2013, Tel-Aviv, Israel, Abstract # AO 013.

83. “Induction of DNA double strand breaks (DBS) in cancer cells by new functionalized sugar analogs” A. Czubatka, K. Salamon, M. Tosik, Z. J. Witczak, T. Poplawski, presented at 48th Congress of the Polish Biochemical Society, September 2-5, 2013, Torun, Poland, Abstract # O4.1

84. “Thio-click domino approach to thio-sugar glycomimetics” Z. J. Witczak, A. Jankowski, N. Patel, S. Silvi, presented at 246th ACS National Meeting, September 9-13, 2013, Indianapolis, IN, Abstract # CARB-10.

85. “Sugar analogs as a novel therapeutic agents against cancer” A. Czubatka, P. Tokarz, Z. J. Witczak, T. Poplawski, presented at 5th Central European Congress of Life Sciences EUROBIOTECH 2013, October 8-11, 2013, Cracow, Poland. Abstract # P5.13.

86. “Thio-click and domino reaction approach in carbohydrate chemistry” Z. J. Witczak, presented at 27th International Carbohydrate Symposium, January 12-17, 2014, Bangalore, India, Abstract # I-A-LL-4.

87. “Cytotoxicity and genotoxicity of thio-sugars and their derivatives” A. Czubatka, P. Tokarz, Z. J. Witczak, T. Poplawski, presented at 27th International Carbohydrate Symposium, January 12-17, 2014, Bangalore, India, Abstract # I-P108.

88. “Thio-click and domino approach to glycomimetics” Z. J. Witczak, presented at 247th ACS National Meeting, March 16-20, 2014, Dallas, TX, Abstract # CARB-0038.

89. “Levoglucosenone derivatives with amino and thiol groups via allylic rearrangements” Roman Bielski, Z. J. Witczak, presented at 248th ACS National Meeting, August 12-17, 2014, San Francisco, CA, Abstract # CARB-0012

90. “Thio-click and domino approach to carbohydrate heterocycles” Z. J. Witczak, presented at 248th ACS National Meeting, August 12-17, 2014, San Francisco, CA, Abstract # CARB-0023

91. “Modification of glucose for targeted cellular delivery. H. Jacobs, Z. J. Witczak, presented at 249th ACS National Meeting, March 12-17, 2015, Denver, CO, Abstract # CARB-0056

92. “Thio-sugars can sensitize human cervix adenocarcinoma (Hela) cancer cells to Bleomycin and ROS generator. J. Sarnik, A. Czubatka, T. Poplawski, Z.J. Witczak, presented at 249th ACS National Meeting, March 12-17, 2015, Denver, CO, Abstract # MEDI-0308

93. “Low glucose level enhances the cytotoxicity of CARB-pharmacophore to cancer cells. A. Czubatka, J. Sarnik, T. Poplawski, Z.J. Witczak Z. J. Witczak, presented at 249th ACS National Meeting, March 12-17, 2015, Denver, CO, Abstract # MEDI-0309.

94. “Thio-sugar motif of carbohydrate functionalized pharmacophore as strategic approach to the design of carbohydrate therapeutics” Z. J. Witczak, presented at 18th European Carbohydrate Symposium, August 2-6, 2015, Moscow, Russia, Abstract # KL-12.

95. “Thio-click and domino approaches to carbohydrate heterocycles” Z. J. Witczak, R. Bielski, T. Grove presented at 18th European Carbohydrate Symposium, August 2-6, 2015, Moscow, Russia, Abstract # PS1-3.

96. “Possible genotoxic effect exerted by thio-sugars in cancer cells via oxidative induction of DNA” A. Czubatka, A. Macieja, J. Sarnik, T. Poplawski, Z. J. Witczak, presented at the 250th ACS National Meeting, August 16-20, 2015, Boston, MA, Abstract # MED-0192.

97. “First synthesis of 2-aminoacetyl-2,3-dideoxy-D-glucose” T. Grove, Z. J. Witczak, R. Bielski, presented at the 250th ACS National Meeting, August 16-20, 2015, Boston, MA, Abstract # CARB-0098.

98. “Novel synthesis of Methyl- 2 acetamido- 2,3-dideoxy-D-glucopyranoside as subsequent unit of non-resistant aminoglycoside antibiotics T. Grove, Z. J. Witczak, R. Bielski, presented at the 14th International Conference of Antibiotics and other Bioactive Compounds ACS National Meeting, October 13-16, 2015, Galveston, TX, Abstract # P-29

99. ”Sequential thiols recognition in coupling of functionalized carbohydrates” Z. J. Witczak, R. Bielski, presented at the Pacifichem 2015, Honolulu, Hawaii, December 15-20 2015, Abstract # BIOL 220.

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100. “Sacrificial units in coupling and decoupling (CAD) of diverse molecules” R. Bielski, Z. J. Witczak, presented at the Pacifichem 2015, Honolulu, Hawaii, December 15-20 2015, Abstract # BIOL 224.

101. “Thio-click and domino approaches to thio-glycomimetics” Z. J. Witczak, presented at the Pacifichem 2015, Honolulu, Hawaii, December 15-20 2015, Abstract # ORGN-2160.

102. “Thio-disaccharides induces an oxidative stress that kills cervix epitheloid carcinoma cells” Z. J. Witczak, J. Sarnik, A. Czubatka, A. Macieja, T. Poplawski, presented at the 251th ACS National Meeting, March 12-17, 2016, San Diego, CA, Abstract # MEDI-0052

103. “Evaluation of functional carb-pharmacophores as a potential inhibitors of tubercle bacilli” M. Korycka-Machala, A. Brzostek, Z. J. Witczak, J. Dziadek, presented at the 251th ACS National Meeting, March 12-17, 2016, San Diego, CA, Abstract # MEDI-0131

104. “Synthesis of fluorinated glucopyranosyl selenoureas as new generation of glucosidase inhibitors” Z. J. Witczak, G. Mloston, M. Celeda, presented at the 251th ACS National Meeting, March 12-17, 2016, San Diego, CA, Abstract # ORGN-0455

105. “Thio-click tools and coupling strategies for synthesis of carbohydrate glycomimetics” Z. J. Witczak, presented at the 251th ACS National Meeting, March 12-17, 2016, San Diego, CA, Abstract # CARB-093.

106. “Thio-linked glycoside ketones and heterocycles as new generation of glucosidase inhibitors” Z. J. Witczak, presented at the 251th ACS National Meeting, March 12-17, 2016, San Diego, CA, Abstract # CARB-019.

107. “Thio-and thio-bromo "click" approaches to carbohydrate functionalized thioglycosides” A. Mauger, Z. J. Witczak, R. Bielski, D. Mencer, presented at the 2016 MARM, College of Mount Saint Vincent, June 9-12, 2016, Riverdale, NY, Abstract # 419.

108. “Thio-functionalization of dihydrolevoglucosenone at C-3 via aldol condensation with thienyl aldehydes” Z. J. Witczak, R. Bielski, presented at the 28th International Carbohydrate Symposium, July 17-22, 2016, New Orleans, LA, Abstract # 286.

109. “Novel S-glycosylated thiosemicarbazide act as potent anticancer agent in breast, cervix and ovarian cancer cells” J. Sarnik, A. Czubatka-Bienkowska, A. Macieja, Z. J. Witczak, T. Poplawski, presented at the 28th International Carbohydrate Symposium, July 17-22, 2016, New Orleans, LA, Abstract # 287

110. “Novel thio-sugar analog act as potent anticancer agent in cervical cancer cells through induction of oxidative stress” A. Czubatka-Bienkowska, J. Sarnik, A. Macieja, Z. J. Witczak, T. Poplawski, presented at the 28th International Carbohydrate Symposium, July 17-22, 2016, New Orleans, LA, Abstract # 288

111. “The novel adamantane derivatives selectively and efficiently inhibits cis-platin resistant ovarian cancer cell line growth” A. Czubatka-Bienkowska, J. Sarnik, A., Macieja, Z. J. Witczak, T. Poplawski, presented at the 252th ACS National Meeting, August 20-24, 2016, Philadelphia, PA, Abstract # MEDI-0331

112. “The synthesis and cytotoxic effect of novel glycosylated thiosemicarbazides and their analogs as anticancer agents” A. Czubatka-Bienkowska, J. Sarnik, A., Macieja, Z. J. Witczak, T. Poplawski, presented at the 252th ACS National Meeting, August 20-24, 2016, Philadelphia, PA, Abstract # MEDI-0332

113. "The synthesis characterization, molecular modeling and potential anticancer activities of novel 1,3,4-thiadiazole derivative” A. Czubatka-Bienkowska, J. Sarnik, A., Macieja, Z. J. Witczak, T. Poplawski, presented at the 252th ACS National Meeting, August 20-24, 2016, Philadelphia, PA, Abstract # MEDI-0323

114. “Thio-and thio-bromo click approach to new carbohydrate functionalized adamantanes” A. Mauger, Z. J. Witczak, R. Bielski, D. Mencer, presented at the 252th ACS National Meeting, August 20-24, 2016, Philadelphia, PA, Abstract # ORGN-0689

115. “Anticancer activity of exo-cyclic carbohydrate enones containing thiophene and pyrolle moieties” J. Sarnik, A. Czubatka-Bienkowska, A. Macieja, Z. J. Witczak, R. Bielski, T. Poplawski, presented at the 253th ACS National Meeting, April 2-6, 2017, San Francisco, CA, Abstract # MEDI-0173.

116. “Novel carbohydrate functionalized thiosemicarbazones evoked DNA damage in cancer cell lines” J. Sarnik, A. Czubatka-Bienkowska, A. Macieja, Z. J. Witczak, T. Poplawski, presented at the 253th ACS National Meeting, April 2-6, 2017, San Francisco, CA, Abstract # MEDI-0174.

117. “Synthesis of novel exo-cyclic α,β-unsturated dihydrolevoglucosenone derivatives via direct aldol condensation” R. Hohol. Z. J. Witczak, D. E. Mencer, presented at the 253th ACS National Meeting, April 2-6, 2017, San Francisco, CA, Abstract # ORGN- 774.

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118. “Functional CARB-Pharmacophores with sulfur bridge modulate Redox homeostasis in glioblastoma cells” J. Sarnik, A. Czubatka-Bienkowska, A. Macieja, Z. J. Witczak, T. Poplawski, presented at the 19th European Carbohydrate Symposium, July 2-6, 2017, Barcelona, Spain, Abstract # P 157.

119. “Thio-click functionalization of unsaturated enones as strategic approach to the design of new carbohydrate therapeutics” Z. J. Witczak, R. Bielski, presented at the 19th European Carbohydrate Symposium, July 2-6, 2017, Barcelona, Spain, Abstract # P234.

120. “Anticancer activity and mechanism of action of novel S-glycosylated thiosemicarbazides” A. Czubatka-Bienkowska, J. Sarnik, A. Macieja, Z. J. Witczak, T. Poplawski, presented at the 19th European Carbohydrate Symposium, July 2-6, 2017, Barcelona, Spain, Abstract # P 327.

121. “Thio-functionalization of levoglucosenone via thiol enone Michaela addition (TEMA)” Z. J. Witczak, A. Mauger, R. Bielski, presented at the 19th European Carbohydrate Symposium, July 2-6, 2017, Barcelona, Spain, New, Abstract # P 388.

122. “Characterization of the degree of substitution of sodium carboxymethyl cellulose by conductometric titration” H. Jacobs, Z. J. Witczak, T. Hodle, presented at the 254th ACS National Meeting, August 20-24, 2017, Washington DC, Abstract # CARB-43.

123. “Thio-click functionalization of carbohydrate exo-cyclic enones via thiol enone Michael addition (TEMA)” W. McLay, Z. J. Witczak, R. Bielski, presented at the 254th ACS National Meeting, August 20-24, 2017, Washington DC, Abstract # CARB-44.

124. “Stereoselective thio-click functionalization of conjugated heterocyclic chalcone synthons with 1-thiosugars” S. Jang, E. Kweiba-Yamouth, Z. J. Witczak, presented at the 254th ACS National Meeting, August 20-24, 2017, Washington DC, Abstract # CARB-45

125. “Synthesis of novel exo-cyclic carbohydrate enones from dihydrolevoglucosenone via direct aldol condensation with aromatic aldehydes” R. Hohol. Z. J. Witczak, D. E. Mencer, presented at the 254th ACS National Meeting, August 20-24, 2017, Washington DC, Abstract # CARB-46.

126. “Novel carbohydrate functionalized thiosemicarbazones evoked DNA damage in cancer cell lines” J. Sarnik, A. Czubatka-Bienkowska, A. Macieja, Z. J. Witczak, T. Poplawski, presented at the 254th ACS National Meeting, August 20-24, 2017, Washington DC, Abstract # MEDI-317.

PATENTS GRANTED (5) 1. “Synthesis of 2-Styrylbenzoxazoles,” Z. J. Witczak and M. Krolikowska, Polish Patent No. PL. 110,039:

Chem. Abstr., 96, 141837j, (1982). 2. “Synthesis of 2-Styrylbenzoxazoles,” Z. J. Witczak and M. Krolikowska, Polish Patent No. PL. 110,464:

Chem. Abstr., 96, 142838k, (1982). 3. “R.G. Chiou, C.C. Brown, J. A. Little, A. H. Young R.V. Schanefelt, D.W. Harris, K. D. Stanley, H. D.

Coontz, C. J. Hamdan, J. A. Wolf-Rueff, L.A. Slowinski. K. R. Anderson, W. F. Lehnhardt, Z. J. Witczak, Method of Preparing Reduced Fat Foods U.S. Patent 5,378,286: January 3, 1995.

4. “R.G. Chiou, C.C. Brown, J. A. Little, A. H. Young R.V. Schanefelt, D.W. Harris, K. D. Stanley, H. D. Coontz, L.A. Slowinski. K. R. Anderson, W. F. Lehnhardt, Z. J. Witczak, Method of Preparing Reduced Fat Foods, US Patent 6,113,976; September 5. 2000.

5. “Boron conjugated saccharide analogs, and methods of use for charged particle radiotherapy” Z. J. Witczak, F.W. Fischer, U.S Patent Application # (2006).

TEACHING 1991- 1999, The University of Connecticut, School of Pharmacy, undergraduate and graduate courses in Natural

Products Chemistry, Biosynthesis and Pharmacognosy. Adviser to M.S. and Ph.D. students, postdoctoral fellows: medicinal & natural product chemistry, biotechnology, bioorganic and organic chemistry.

Pharm 212- Physico-chemical Principals of Pharmacy (Vitamins, Carbohydrates, Antibiotics -Immunology, Immunotherapy, Glycobiology, Vaccines, Antigen-antibody reaction, Carbohydrate vaccines- immunotherapeutics, & pharmacology). Pharm 217- Laboratory Course for Pharm 212. Pharm 318- Chemistry of Natural Products (Synthesis & biosynthesis)

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Pharm 377- Biosynthesis (Carbohydrate metabolism & Gluconeogenesis, biotechnology). Pharm 234- Bioorganic Chem. II (Immunochemistry, carbohydrate antigens -vaccines). 1991- 1997 Seminar Program Coordinator at the Department of Pharmaceutical Sciences, Medicinal and Natural

Products Chemistry Discipline, School of Pharmacy, University of Connecticut. 2000-present- Wilkes University, Nesbitt School of Pharmacy,

PHA 552-Principles of Bioorganic and Medicinal Chemistry. PHA 421, 423, 428, Pharmacotherapeutics,

SUPERVISORY TEACHING ADVISORY COMMITTEES

Medical University of Lodz, Department of Organic Chemistry M. Sc. directly supervised:

Joanna Sygula-Kociolek M.Sc. 1974 Maria Mietkiewicz M.Sc. 1976 Maria Golaszewska, M.Sc. 1977 Halina Jasko M.Sc. 1978 Eleonora Bogut-Rawska M.Sc. 1979 Henryk Cierpikowski, M.Sc. 1980

Major Advisor, Ph.D. Thesis Advisory Committee,

Jianmin Sun, The University of Connecticut, School of Pharmacy, 1992-1994. (MS. 1994), (Ph.D 1998) Hong Chen, The University of Connecticut, School of Pharmacy, 1995-1997. (MS. 1997), Ying Li, The University of Connecticut, School of Pharmacy, 1994-1996. (MS. 1996), Xin-Zhong Lai, The University of Connecticut, School of Pharmacy, 1996-1998. (MS 1997)

Major Advisor, M.S. UConn Honor Scholar, Thesis Advisory Committee,

R. Chhabra* The University of Connecticut, School of Pharmacy, (MS. 1996)

Students (Undergraduate and Graduate) Directly Supervised & Graduated:

H. Chen 1995- 1997 (MS 1997) R. Chhabra* 1995-1998(MS Honor student) J. Chojnacki 1995- 1998 (MS Honor student) D. Boryczewski 1996-1998 (MS 1998) S. Chow 1996- 1998 (MS Honor student) X. Z. Lai 1996-1998 R. Mielguj# 1992, Zeinab El-Said, 1992-1993 Y. Li, 1994- 1995 (MS 1995) P. Kaplon 1998- 1999 (MS 1999) M. Kolodziej 1998- 1999 (MS 1997)

Wilkes University, School of Pharmacy

K. Cassidy 2003-2004 G. Milewich 2002-2004 S. Bortz 2004-2005 M.Tovbina 2004-2005 P. Hlavinka 2003-2006 J. Danowski 2003-2006 D. Lorchak 2004-2007 J Dwyer 2003-2006 N. Nguyen 2005-2007 P. Pham 2003-2006

*1996 Undergraduate Research Scholarship Recipient of American Society of Pharmacognosy, UConn University Scholar. # Deceased, April 12, 2010.

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Y. Kimura 2004-2005 C. Cassett 2006-2007 J. Ritter 2007-2009 A. Jankowski 2007-2011 S. Silvi 2009-2011 R. Rampulla 2009-2011 N. Patel 2010-2013 T. Bridges 2012-2012 B. Dudeck 2012-2012 A. Lopez 2012-2013 N. Kocon 2013-2014 E. Takin 2013-2014 T. Grove 2014-2016 A. Mauger 2015-2016 S. Mullen 2015-2016 S. Jang 2016-2017 R. Hohol 2016-2017 E. Kweiba-Yamoah 2016-2017 W. McLay 2016- C. Oldt 2017- H. Arcure 2017- J. Lorenzo 2017- N. Jankowski 2017- Post-doctoral Research Associates and Industrial associates directly supervised:

Dr. Chi-Cheng Chen 1984-1986 Dr. Xien-Qun Xie 1993-1995 Dr. Shiwei Lin 1985-1987 Peter Churukian 1987-1991

James Anderson 1998-1999

* Updated October 5, 2017.