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UNIVERSITY OF MAIDUGURI

OFFICE OF THE VICE-CHANCELLOR

CENTRE FOR RESEARCH AND INNOVATION FORMAT FOR COMPILING RESEARCH COMPENDIUM

Research Title:- Rubella virus infection among pregnant women in Zaria, Kaduna, Nigeria: An association between antibody level and community setting.

The association between rubella IgG antibody level and community setting was investigated among pregnant women attending antenatal clinic in some health centres in Zaria using Enzyme Linked Immunosorbent Assay. Out of four hundred and sixty nine samples (469) assayed, 62.7% of pregnant women in the low socio-economic setting were found to be seropositive. T-test analysis (p<0.05) revealed a significant statistical association between antibody level and community setting. Vaccination against rubella need therefore be included in the Nigerian immunization policy to prevent any possible outbreak.

Impact Factor:-

Researchers Name(s):- (Lead Researcher First)

Oyinloye, S. O., Ahmad, A.A. and Jatau, E.D

Researchers Address(es):- Department of Microbiology, Ahmadu Bello University Zaria, Nigeria.

Correspondence Address:- (Tel. No., Email, Physical)

Department of Microbiology, Ahmadu Bello University Zaria, Nigeria. [email protected] +234803 616 1371

Publication Status:- (published/unpublished)

Published

Source of Publication:- (Journal, Periodical etc, Vol. page Nos)

Biological and Environmental Sciences Journal for the Tropics. 6(1): 154 – 156

Year of Publication:- 2009 Source of Funding and Amount ($, £, # )

Self-funded N3000

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Research Title:- A community based seroepidemiologic survey of hepatits B surface antigen among pregnant women in Taraba state, Nigeria.

Abstract:- This preliminary study was conducted to determine the seroprevalence of HBV infection among pregnant women (single and married) attending antenatal clinic at a community health centre in Taraba State, Nigeria. Blood samples from volunteers (n=100) were collected and analysed for detection of hepatitis B surface antigen (HBsAg) by Enzyme Linked Immunosorbent Assay (Standard Diagnostic, Inc, Korea). An overall seroprevalence of 6% was found. There was a significant association among two age groups: 21 – 23years (X2 cal 16.34//X2 table 15.51p<0.05) and 28 – 34 years (X2 cal 11.25//X2 table 11.07p<0.05). Previous studies have shown statistical association between seropositivity and some risk factors. This preliminary study has shown that seroprevalence of HBV infection is of intermediate endemicity. Therefore HBV vaccine needs to be introduced to alleviate impact of the disease.

Impact Factor:-


Oyinloye, S.O1., Dahiru, A1., Ajayi, B2. and Lawan, M.A2

Researchers Address(es):- (1)Department of Microbiology, Faculty of Science, University of Maiduguri, Nigeria. (2)Department of Immunology, UMTH, Maiduguri, Nigeria.


Department of Microbiology, Faculty of Science, University of Maiduguri, [email protected] +234803 616 1371


Published




Self-funded N3000

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Research Title:- Seroprevalence of cytomegalovirus IgG antibody among pregnant women in Nguru, Yobe State, Nigeria.

Abstract:- Cytomegalovirus is a major public problem throughout the world especially in individuals whose immune systems are immature or weakened such as AIDs patients, organ transplant patients and pregnant women. The virus remains the leading cause of congenital infectious viral cause of birth defects such as mental retardation and deafness. A cross sectional study was carried out to determine the seroprevalence of the immunoglobulin G (IgG) antibody to cytomegalovirus among pregnant women attending antenatal clinic in Nguru, Yobe state. Ninety samples were screened using Enzyme Linked Immunosorbent Assay (Standard Diagnostic, Inc, USA). An overall prevalence of 90% (X2 cal 13.43 p=0.05) was obtained. There was no correlation between miscarriage and still (r= 0.43). socioeconomic condition did not influence rate of infection ( t cal 0.30//t-tab 1.9). It is concluded that rate of cytomegalovirus infection in the study area is high and protends potentials health hazard pregnant women and their fetuses are exposed to.

Impact Factor:-


Oyinloye, S.O1., Sunji, A1., Ajayi, B2. and Lawan, M.A2



Department of Microbiology, Faculty of Science, University of Maiduguri, Borno State, Nigeria. [email protected] +234803 616 1371

Publication Status:- Published Source of Publication:- (Journal, Periodical etc, Vol. page Nos)



Self-funded: N5000

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Research Title:- Hepatitis C and human immunodeficiency virus co-infection among pregnant women attending a private hospital in Gombe state, North-eastern Nigeria.

Abstract:- Human immunodeficiency virus/ Hepatitis C (HIV/HCV) co-infection has a negative impact on the disease caused by HCV, accelerating its evolution while some studies have asscoaited HCV co-infection with a faster HIV progression. The risk of a pregnant woman passing the hepatitis C virus to her unborn child has been related to the levels of quantitative RNA in the blood and also whether she is HIV positive. This seroepidemiologic cross-sectional study was carried out to determine the sero-prevalence of hepatitis C as well as the HCV/HIV co-infection in pregnant women attending antenatal care. Samples were analysed colorimetrically using ELISA microwell reader at 450nm (Standard Diadnostics, Inc, Korea). Information obtained included age, trimester, blood group, surgical and blood transfusion history. The data was presented in tables and percentages of the total participants (n=100) selected at random, seroprevalence was estimated for HCV, HIV and HCV/HIV as 6%, 1% and 1% respectively. This study highlights that HCV infection is prevalent among pregnant women with some co-infected with HIV, hence the need to ensure proper management strategy in order to truncate possibilities of infecting the unborn fetus.

Impact Factor:-


Oyinloye, S.O1., Babadidi, M.H2., Sarkin Shanu, M1. and Ajayi, B3.




Publication Status:- Published Source of Publication:- (Journal, Periodical etc, Vol. )



Self-funded: N5000

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Research Title:- Seroprevalence herpes simplex-1 specific IgM amongst pregnant women in Maiduguri, Borno State, Nigeria.

Abstract:-, Genital herpes is a viral infection caused by herpes simplex virus type 1 and type 2 (HSV-1 or 2). The acquisition of genital herpes during pregnancy has been associated with spontaneous abortion, intrauterine growth retardation, preterm labour, congenital and neonatal herpes infections (infection in a new born within 28 days of birth). This research was designed to evaluate seroprevalence of HSV-1 IgM antibodies among pregnant women using Enzyme Linked Immunosorbent Assay (Standard Diagnostic, Inc, USA). A structured questionnaire was used to collect socio-demographic data. A prevalence of 58.7% ((X2 cal 13.66//X2 table 67.50, p=0.05) was obtained. Pregnant women within 20 – 24 years had the prevalence of 65% ((X2 cal 2.08//X2 tab 37.65, p=0.05), while socioeconomic status was not a factor in infection (t- cal 0.91// t-tab 1.98, p=0.05). Thirty one of fifty four pregnant women (57.4%) in late pregnancy term were IgM seropositive. The frequency of acute HSV-1 infcetion among these pregnant women poses serious health hazard to their fetuses and other women of child bearing age who are unexposed as yet.

Impact Factor:-


Oyinloye, S.O1., Abdulmalik, B1., Ajayi, B2. and Lawan, M.A2



Department of Microbiology, Faculty of Science, University of Maiduguri, Nigeria. [email protected] +234803 616 1371

Publication Status:- Published Source of Publication:- (Journal, Periodical etc, Vol. )



Self-funded: N5000

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Research Title:- Sero-Evidence Of Hepatitis B Surface Antigen Among Expectant Mothers In Nguru, Yobe state, Nigerias such as induced premature

Abstract:- Acute/chronic hepatitis in pregnancy has been shown to be associated with vertical transmission or high risk of maternal complication such as induced premature labour, and prematurity with its attendant effects. This study was designed to establish the serological evidence of hepatitis b surface antigen among expectant mothers attending antenatal care at a tertiary hospital in Nguru, Yobe state. Ninety one samples were screened using the enzyme linked immunosorbent Assay (ELISA) (Diagnostic automation/Cortez Diagnostics, Inc, USA). Of these, 8.8% (X2 cal 90.97, p=0.05) of them were positive for hepatitis B surface antigen. An increase in prevalence based on age group was observed, those within 17-21 , 22-26, 27-31, 32-36 and >36 years had prevalence of 3.2%, 4.8%, 5.9%, 20% and 28.6% respectively. Expectant mothers in the second trimester had the highest prevalence of 16.7% (4/24). There is no association between infection and socioeconomic status of the expectant mothers (t cal 0.65/t tab 1.98 p=0.05). This result indicates that hepatitis B infection is of high endemicity in the study area and the rate of infection increases with age. Vaccination of women of all age group and susceptible new born is hereby recommended.

Impact Factor:- 5


Oyinloye, S.O1., Mohd-Taki, B1.and Lawan, M.A2





Published

Source of Publication:-

Conference Proceeding, 1st International Conference of School of Technology Education (STE), FUT Minna,

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(Journal, Periodical etc, Vol. page Nos) Year of Publication:- 2013 Source of Funding and Amount ($, £, # )

Self-funded; N13,000

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Research Title:- Bacteria contamination of automated teller machine keypads in university of Maiduguri, Borno state, Nigeria.

Abstract:- Automated Teller Machines (ATMs) just like microbes are becoming ubiquitous and are having an increased influence in everyday activity due to their conveniences for financial transactions. They may act as source of bacteria contamination. This pilot study was designed to isolate and identify the bacteria on the keypads of the ATMs in university of Maiduguri main campus. A total of 168 samples were collected by swabbing, within the month of June 2013, the surfaces of four randomly selected ATMs keypads and cultured aseptically on Manitol salt agar, Eosin methylene blue and MacConkey agar. Species identified by standard biochemical methods included Staphylococcus aureus: 82(48.8%), Klebsiella sp. 62( 36.9%) and Escherichia coli 24(14.3%). Coagulase positive 60(73.5%) and coagulase negative 22(26.5%) S. aureus were identified. These findings suggest bacteria contamination of keypads of ATMs and portends possibility of infection and transmission among users.

Impact Factor:- 5


Oyinloye, S.O1. and Momoh, R

Researchers Address(es):- Department of Microbiology, Faculty of Science, University of Maiduguri, Borno State, Nigeria.




Published


Conference Proceeding, 1st International Conference of School of Technology Education (STE), FUT Minna,


Self-funded; N13,000

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Research Title:- Malaria Parasitaemia among Different Genotypic Groups in Idah Metropolis, Kogi State,Nigeria

Abstract:- This work is aimed at investigating the distribution of malaria parasites among the different genotypic groups in Idah metropolis. The blood specimens were collected in each while presence or absence of malaria parasite was determined between August to October 2011 using blood smear microscopic methods and the haemoglobin type were determined using the gel electrophoresis methods. A total of 714 blood samples and their slides were examined out of which 414(42.3%) were Hb AA, 75 (40%) were Hb SS, while 231(32.5%) were Hb AS, with the male population having greater prevalence 189 (53.4%). The malaria parasites had much prevalence in the AA genotype than any other group in this study.

Impact Factor:- 6.5


1Yahaya O., 1Umar I.O., 2Dashen M.M., 3Oyinloye S.O., 4Yabefa J.A., & 1Okwunjo, O.C.

Researchers Address(es):- 1Department of Science Laboratory Technology, Federal Polytechnic, Idah, Kogi State. 2Department of Microbiology, University of Jos, Nigeria 3Department of Microbiology, University of Maiduguri, Nigeria. 4Department of Chemistry, Collage of Education, Brass-Island, Bayelsa State, Nigeria


1Department of Science Laboratory Technology, Federal Polytechnic, Idah, Kogi State E-mail: [email protected]


Published


Journal of Medical and Applied Biosciences, 5(1): 94 – 99

Year of Publication:- 2013 Source of Funding and Amount ($, £, #

Self-funded :

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Research Title:- Serological Screening for Ante-Natal Toxoplasmosis in Maiduguri Municipal Council, Borno State, Nigeria

Abstract:- Toxoplasma gondii infection causes devastating defects including, blindness, neurological impairment and mental retardation in congenitally infected children. Congenital infection occurs when a woman becomes infected during pregnancy; and the severity of the illness is related to the trimester period. This research was designed to evaluate the seroprevalence of toxoplasmosis amongst pregnant women (n=90) using enzyme linked immunosorbent assay (ELISA) kit (Cortez Diagnostics Inc. USA). A structured questionnaire was used to collect socio-demographic data. A significant (x2 Cal 233.0/ x2 tab 124.1, p=0.01) overall prevalence of 22.2% (20/90) was obtained. Pregnant women within 25-29years had the highest prevalence of 33.3% (3/9); this was significant (x2 Cal 35.85/ x2 tab 9.21, p=0.01). An association between high levels of toxoplasma IgG and miscarriage was established in four of twenty five women who had suffered miscarriage (t cal 5.3/t tab 2.81, p=0.01). The results presented indicate that toxoplasmosis is a significant public health burden in the area of study, which requires drastic remedial measures.

Impact Factor:- 7.8


Oyinloye, S.O1., Igila-Atsibee, M1., Ajayi, B2. and Lawan, M.A2.

Researchers Address(es):- (1)Department of Microbiology, Faculty of Science, University of Maiduguri, Nigeria. (2)Department of Immunology, UMTH, Maiduguri.




Published

Source of Publication:- African Journal of Experimental Microbiology. Vol 15(2) : 91-96


Self-funded: N30,000

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Research Title:- Seroprevalence survey of rubella antibodies among pregnant women in Maiduguri, Borno State, Nigeria.

Abstract:- Rubella is a vaccine- preventable viral infection. Its etiologic agent, rubella virus was identified as a human teratogen capable of causing spectrum of birth defects described as congenital rubella syndrome (CRS) if the pregnant mother is infected within the first trimester of pregnancy. A total of 90 pregnant women attending a secondary health care facility in Maiduguri were screened for IgM and IgG antibodies using enzyme linked immunosorbent assay (ELISA) kit (Cortez Diagnostics Inc. USA). Of these, 37.8% (34/90) and 83.3% (75/90) were seropositive for anti-rubella IgM (x2 Cal 5.1; p=0.05) and IgG respectively. Chi-square analysis (x2 Cal 38.38, p=0.05// x2 tab 31.41, p=0.05) revealed an association between miscarriage and IgG antibody level in twenty-one subjects. Pregnant women within 20-24years had the highest prevalence of 40% (36/90)( x2 Cal 4.22, p=0.05) : 44.4% (16/36) of them were seropositive for IgM (x2 Cal 4.31, p=0.05). A marked surge in IgG antibody level, which tantamount acute infection, was observed in 15.6% (14/90)( x2 Cal 19.85, p=0.05) of the pregnant women. Pregnant women in the first trimester seropositive for anti-rubella IgM were 36.4% (4/11), inferring that the fetuses of these women are susceptible to sequelae of rubella. This result highlights the consequence of rubella infection and confirms continuous circulation of rubella virus in the study area. There is need for vaccination of vulnerable population in order to ensure the control /elimination of rubella virus in Nigeria.

Impact Factor:- 6.7


Oyinloye, S.O1., Amama, C.A1., Daniel, R., Ajayi, B. B2. and Lawan, M.A2

Researchers Address(es):- (1)Department of Microbiology, Faculty of Science, University of Maiduguri, Nigeria. (2)Department of Immunology, UMTH, Maiduguri




Published

Source of Publication:- African Journal of Experimental Microbiology. Vol 15(1) : 151-157


Self-funded: N30,000

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Research Title:- Serological evidence of HBV and HDV Co-infection among pregnant women in Maiduguri, Borno State, Nigeria

Abstract:- Hepatitis Delta Virus (HDV) infections only patient that are already infected by hepatitis B Virus (HBV) because this is sub satellite virus which depends on and propagate only in the present of HBV. HDV causes co-infection or super infection which severs complication as compared to only HBV infection. therefore the aim of this study was determine the seroprevalance of HDV (as a co-infection with HBV) in Maiduguri, Borno state , by using CORTEZ DIAGNOSTIC , INC .,USA. Hepatitis B virus (HBV) and hepatitis delta virus (HDV) are highly endemic in Africa however, little information is available on the origin, circulation and genetic diversity of those viruses in Central Africa: this hepatitis B virus Infection is a pandemic and chronic infection may lead to chronic liver diseases which often lethal, HDV base on my study 6.6% one seropositive while 1 co-infection with HBsAg and HDsAg are seropositive. Key Words: Serological, HBV, HDV and Infection.

Impact Factor:- 5.8


Jidda H.D., Oyinloye, S.O., Bello, H., Isa, M.A. and Goni, H.Y.

Researchers Address(es):- Department of Microbiology, Faculty of Science, University of Maiduguri, Borno State, Nigeria.


Department of Microbiology, P. M. B. 1069, University of Maiduguri, Borno State, Nigeria. [email protected] +234803 616 1371


Published

Source of Publication:-

Journal of Biological and Chemical Research. 33(2): 686-691


Self-funded: $100

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Research Title:- Maternal Seroprevalence of Hepatitis B Virus Serologic Markers among Attendees of a Secondary Health Facility in Maiduguri, Nigeria.

Abstract:- The profile of four hepatitis B virus markers [Hepatitis B surface antigen (HBsAg), antibodies of the immunoglobulin M (IgM) class against the hepatitis B core antigen (IgM anti-HBc), Hepatitis B surface antibody (Anti-HBs) and Hepatitis B envelop antigen (HBeAg)] among pregnant women (n=91), with mean age of 25.96 years, were determined using Enzyme linked immunosorbent assay kit. A significant (p=0.00001) overall sero-prevalence of 8.79%, 36.26%, 6.59% and 7.65% were observed for HBsAg, Anti-HBs, IgM anti-HBc and HBeAg respectively. Forty seven point three percent were susceptible (HBsAg -Ve, IgM anti-HBc -ve and anti-HBs-ve) to hepatitis B virus infection. One of thirteen pregnant women tested positive for HBsAg and HBeAg; this portends high risk of transmission to the fetus. This result portrays the unreliability of using presence of HBsAg as the sole marker for hepatitis B virus infection, high susceptibility to hepatitis B virus infection and the risk of transmission of HBV to fetuses.

Impact Factor:- 6.8


Oyinloye, S. O1., Osunkwo, M1., Taki-Mohd, B1., Ajayi, B. B2. and Lawan, M. A2

Researchers Address(es):- (1)Department of Microbiology, Faculty of Science, University of Maiduguri, Nigeria. (2)Department of Immunology, UMTH, Maiduguri




Published


British Microbiology Research Journal. 11(3): 1-7

Year of Publication:- Source of Funding and Amount ($, £, # )

Self-funded: $100

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Research Title:- A Preliminary Survey of Norovirus And Astrovirus Antigen In Diarrheic Stools Of Children In Borno State, Nigeria

Abstract:- Background: Noroviruses and astroviruses are important agents of acute gastroenteritis among children. Acute gastroenteritis (AGE) is a major cause of morbidity and mortality in pediatric populations world-wide. Globally, an estimated 800 000 infants and young children die from diarrhea every year. Aims: This was a cross-sectional study that included acute diarrheic children presenting in Specialist Hospital, Nursing Home Health Centre and Ngamdu pediatric clinic in Borno state with the aim of detecting norovirus and astrovirus antigen. Two hundred children whose parent/ guardian consented were enrolled in the study. Methodology: Two hundred acute diarrheic and forty one nondiarrheic fecal samples were collected from children aged 5 or less between June 2013 – May 2014. Samples were screened for norovirus and astrovirus antigen using 3rd generation RIDASCREEN ELISA test kit. Demographic data of the children were obtained. Results: All non-diarrheic stools were negative for both antigens whileof the two hundred diarrheic stools screened, a prevalence of 8% and 5% were obtained for norovirus and astrovirus respectively. The proportion of males (6/130) positive for norovirus antigen relative to female (10/70) was found to be significant (p < 0.016199). No significant difference was observed between male and female positive for Astrovirus (p =0.307574). A significant prevalence of norovirus (p = 0.00001) and astrovirus (p = 0.013321) based on age group were obtained. Clinical sign and symptoms of infection with norovirus and Astrovirus between male and female showed no significant difference (p=0.42018). Keywords: norovirus, astrovirus, diarrhea, borno state, nigeria.

Impact Factor:- 7.0


Oyinloye, S. O1., Jatau, E.D2., Aminu, M2. and Ella, E.E2.

Researchers Address(es):- (1)Department of Microbiology, Faculty of Science, University of Maiduguri, Nigeria. (2)Department of Microbiology, Ahmadu Bello University Zaria, Nigeria.

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Published


Global Journal of Medical Research 16(1): 33-37


Self-funded: $210

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Research Title:- The prevalence and predisposing factors of norovirus and astrovirus infection among diarrheic children in north east, Nigeria

Abstract:- This is a case-control study design that aims to determine the prevalence of norovirus and astrovirus infections in diarrheic children in Northeast region of Nigeria. Six hundred diarrheic stools (which were neither mucoid nor blood tinged) of children of 5 years or below were collected between May 2013 – April 2014. They were screened according to the manufacturer’s instruction, using a 3rd generation Ridascreen ELISA kit (R-Biopharm AG, Germany). The control group comprised thirty five non-diarrheic stools. Demographic data were collected via questionnaire administered to parents/guardians of the subjects and analysis was done using online Easy-Chi-square (p<0.05) statistical package. An overall norovirus and astrovirus prevalence of 6.7% (40/600) and 5.0% (30/600) respectively across the Northeast region was obtained. The prevalence of norovirus in Taraba, Bauchi and Borno states was 7 (14/200), 5 (10/200) and 8% (16/200), while that of astrovirus was 5.5 (11/200) 4.5 (9/200) and 5% (10/200), respectively. The sex distribution of number of male relative to female children sampled reveals a preponderance of male (336/600) over female (264/600). Prevalence of norovirus and astrovirus antigen was high in children aged 1 to 2 years across the region. Source of drinking water, nearness of toilet to source of drinking water, hand washing after toilet use, playing with toys, attendance of day care center and educational status of parents were statistically (p<0.05) and significantly contributory factors to infection. The prevalence of norovirus (6.7%) and astrovirus (5.0%) in diarrhea in Northeast Nigeria has shown that both viruses contribute to childhood diarrhea, with most of the children infected below age 2.

Impact Factor:- 7.8


Oyinloye, S. O1., Aminu, M2., Ella, E. E2. and Jatau, E. D2


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Published


Journal of Public Health and Epidemiology. 8(10): 204-210.


Self-funded: $330

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Research Title:- Dengue virus infection in northeast Nigeria: Case study of a squatters’ Camp.

Abstract:- Dengue, a mosquito-borne viral disease, has been reported to

be endemic in Nigeria. Yet it isnot a reportable disease and

diagnosis is neglected. In this cross-sectional study, we

conducted sero-survey of dengue virus specific antibodies

among internally displaced persons. Blood samples were

collected from 90 consenting antenatal subjects and non-

pregnant women/males with febrile complaints. Serological

determination of dengue specific antibodies was carried out

using the enzyme linked Immunosorbent assay (DIAsource

Immuno Assay SA, Belgium). Structured questionnaire was

administered to obtain demographic data. Overall IgM and IgG

prevalence was 74.4% (67/90) and 90% (81/90) respectively.

Also, 85.7% of the pregnant women in 1st trimester was positive

for IgM while 95.2% of them had IgG but there was no

significant difference (p=0.632) between the pregnancy terms

and the antibodies status. The highest proportion (28.9%;13/45)

of the non-pregnant women/males were within the 19-23 years

age bracket. Age stratified distribution of the antibodies was not

found to be significant

(p=0.7562). This finding establishes occurrence of both acute

and chronic infections with dengue virus in Maiduguri and it

corroborates reports from other parts of Nigeria suggesting its

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endemicity. Dengue screening should be included in routine

antenatal test; febrile patients

should also be screened for dengue in order to initiate

appropriate treatment regimen. Impact Factor:- 8.2


Oyinloye, S. O., Wajiroko, M., Lawan, A. M., Umar-Faruq, A, Samuel-Bumba, M., Yusuf, S., Anjikwi, N and Abu-Mohammad, K





Published


International Journal of Perceptions in Public Health 1(1):59-65.


Self-funded US Dollars ($ )

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Research Title:- Prevalence of rotavirus infection in infants and young children with gastroenteritis in two North-East States, Nigeria

Abstract:- Introduction: Rotavirus, is an eleven segmented double stranded ribonucleic acid virus in the family of Reoviridae, and is a leading cause of gastroenteritis among infants and young children.Aims: This study was aimed at conducting a preliminary survey of rotavirus antigen in diarrheic stool of children (< 5 years) in Taraba and Yobe states in Nigeria to determine the prevalence. Methodology: One hundred and fifty children, each, in two north east states (Taraba (TR) and Yobe (YB) Nigeria with acute diarrhea were selected by random sampling in a cross-sectional, hospital-based study. Fifty two non-diarrheic and three hundred diarrheic tool samples from children less than five years old were assayed for rotavirus antigen by enzyme linked immunosorbent assay (Cortez Diagnostic Automation, Inc, USA) kit. Demographic data of the children were collected and result analysed using chi-square.Result: All non-diarrheic stool (n=52) were negative for rotavirus antigen while of the total of 300 children sampled, overall prevalence of 4.0% and 9.3% were obtained in Taraba (mean age = 25.85months) and Yobe (mean age = 25.65months) respectively. Type of toilet used in both states was a factor in infection (TR p=0.007; YB p=0.00004). There was preponderance of infected male over female children in both states but this was not significant (p=0.55; p=0.48). Also, the source of drinking water had no significant effect on the prevalence of infection in both states (TR:

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p=0.177; YB: p=0.134). Playing with toys was found to serve as a predisposing factor of infection in Yobe state only (p=0.001). Conclusion: The result of this study shows that rotavirus is a significant aetiologic agent of diarrhea among infants and young children in the study area. Public enlightenment on the predisposing factors to infection should be emphasized in order to mitigate transmission. Also, determination of the circulating genotypes in the study area is recommended.

Impact Factor:- 7.5


Oyinloye, S. O., Idika, J., Abdullahi, M., Lawan M.A., Dahiru, A. and Salihu, A.

Researchers Address(es):- Correspondence Address:- (Tel. No., Email, Physical)



Published


British Journal of Medicine and Medical Research: 20(2): 1-7.


Self-funded US Dollars ($ 100)

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Research Title:-

Abstract:- Impact Factor:-


Researchers Address(es):- Correspondence Address:- (Tel. No., Email, Physical)

Department of Microbiology, P. M. B. 1069, University of Maiduguri, Borno State, Nigeria.


Published


Journal


Self-funded US Dollars ($ )

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