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“You’ll Never Walk Alone”Duchene Muscular Dystrophy

By Zsanell Go

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+Thesis Statement

“With the help of supporters, modern research advances in therapeutic management of Duchene muscular dystrophy increase survival and quality of life of today’s patients and bring realistic optimism towards its ultimate cure for the next generation.”http://hcms-renaissance-research.wikispaces.com/file/view/thesis_funnel.png

+IntroductionDiscuss Jerry Lewis’ dedication to the Muscular Dystrophy

Association (MDA).

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+Intro +: Darius Goes West!

Add this equally inspiring experience of Darius Weems, who he himself experienced Duchene Muscular Dystrophy.

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+Brief definition &Detection/ Diagnosis Duchene muscular dystrophy is a progressive muscular

disease caused by the deficiency of dystrophin, a muscle protein, leading to complete loss of ambulation and death by heart or pulmonary deterioration in the late teens or early twenties.

How to determine what causes MD. Scientific Analysis.

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+Symptoms of DMD In as early as the preschool years, boys with DMD will

experience trouble standing or walking, Muscle weakness, & enlarged calves called pseudohypertrophy.

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+Progression of Symptoms Additional common symptoms include scoliosis, toe-

walking, and permanent shortening or deformity of the ankles, knees, and hips. By ages 8 to 13 years of age, they would be unable to walk and require wheelchairs.

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+Future Treatment Possibilities:What advances in Research/Treatments/Cure/Clinical Trials? Doctors worldwide have made encouraging breakthroughs like: Glucocorticoid corticosteroid therapy, Myoblast transplantation, Genetic and pharmacologic therapy, & axon skipping method.

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+ Conclude!Restate of thesis & brief note to

leave the reader with.

How can we help and be the vehicle towards the cure?Lewis and Weems changed the lives of those with DMD and so can we. “The big fat road connects us all.” •Understand DMD•Make a donation•Sponsor a DMD screening test•Support fundraisers like purchasing an award-winning DVD Darius Goes West