xy = xx= female male female karyotype male karyotype
TRANSCRIPT
SEX DETERMINATION AND SEX-LINKED INHERITANCE
Sex Determination
Xy =
XX= female
male
Female karyotype
Male karyotype
X and Y chromosomes
Nondisjunction- Jigsaw
Nondisjunction: failure of chromosomes to separate during meiosis 1 or 2
Results in an extra chromosome or a missing chromosome
http://glencoe.mcgraw-hill.com/olcweb/cgi/pluginpop.cgi?it=swf::550::400::/sites/dl/free/0078757134/383925/Chapter11_NGS_VisualizingNondisjunction_10_10_06.swf::Visualizing%20Nondisjunction
XO- Turner Syndrome XXX- Trisomy X XXY- klinefelter Syndrome XYY- Jacob Syndrome
Very often, symptoms are slight due to X-inactivation and the small amount of genes found on the Y chromosome
SEX CHROMOSOMES CONTAIN GENES THAT CODE FOR TRAITS
=SEX LINKED TRAITS
Both Males and Females Inherit X Chromosomes: Males XY; Females
XX
X-LINKED GENES: Genes carried on the X chromosomeHemophilia
Color blindnessBaldness Muscular Dystrophy
Mother Without hemophilia = X X
Without hemophilia = X X
With hemophilia = X X Father
Without hemophilia = X y
With hemophilia = X y
H H
H h
h h
CARRIER
H
h
Key!