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36
GBD 2004 SUMMARY TABLES October 2008 Health statistics and informatics Department, World Health Organization, Geneva, Switzerland http://www.who.int/evidence/bod NOTES for Tables a Income categories are as defined by the World Bank's World Development Report 2004. Countries are divided among income groups according to 2004 gross national income (GNI) per capita. The groups are low income (US$825 or less), lower middle income (US$826–3255), upper middle income (US$3256–10 065), and high income (US$10 066 or more). A list of countries and territories by income category is given below. b World totals for males and females include residual populations not included in the World Bank income categories. c For the WHO regions of the Americas, Europe and Western Pacific, these figures include late effects of polio cases with onset prior to regional certification of polio eradication in 1994, 2000 and 2002, respectively. d Does not include liver cancer and cirrhosis resulting from chronic hepatitis virus infection. THE GLOBAL BURDEN OF DISEASE: UPDATED PROJECTIONS This workbook contains summary projections of mortality by cause, sex, age and region. These projections are an up projections released in 2006 (1), and use methods similar to those applied in the original GBD study (2). A set of simple models have been used to project future health trends for baseline, optimistic and pessimistic scenarios, b projections of economic and social development, and using the historically observed relationships of these with ca mortality rates. These updated projections have been prepared using the GBD 2004 results as a starting-point (3). The methods used the same as those previously published (1), with the following changes: (1) Projections of income per capita were revised to take account of World Bank revisions to purchasing power pari conversion rates (4) and latest World Bank regional projections of real growth per annum in income per capita (5); (2) Countries for which low-income regression coefficients were used were revised to take account of revised count and projections; (3) The projection regression equations were recalibrated so that back projections of child mortality rates from 2 matched observed trends for World Bank regions. In the recalibrated projections, the regression coefficient for human capital was left un regression coefficient for time (a proxy for technological change) was set to zero for low-income countries in the WHO African, European, So Western Pacific Regions; (4) Baseline, optimistic and pessimistic projections for HIV incidence and mortality were based on updated UNAIDS incorporating different assumptions about future trends in scale-up of antiretroviral therapy coverage (see below); (5) Relative risks for diabetes mellitus mortality associated with increasing levels of body mass index (kg/m2) we downwards based on latest information from the Asia Pacific Cohorts study (6). Optimistic projections for HIV are based on UNAIDS projections under a "phased scale-up to universal access" scena assumes different rates of scale-up for coverage of antiretroviral treatment (ART) for each country based on curre coverage and capacity, with countries reaching universal access (80% coverage for those "in need of treatment") by latest (7). From 2016 to 2030, coverage is assumed to remain constant and HIV incidence to decrease by around 6% p children and 4.5% per annum for adults. These projections are less firm than the base year assessments for 2004, and provide “business as usual” projectio specified assumptions that do not specifically take account of trends in major risk factors apart from tobacco smo limited extent, overweight and obesity. This spreadsheet includes point estimates for projected deaths by region, sex. Explicit uncertainty ranges are not included here, uncertainty in projections is better conveyed through comp optimistic and pessimistic scenarios with varying input assumptions. The number of significant figures displayed i in this this Excel workbook do not provide information on uncertainty ranges of projected estimates. The optimist pessimistic projection scenarios provide an indication of the sensitivity of the projections to variations in inpu regarding projected income per capita, human capital, smoking intensity, and TB and HIV mortality. These scenarios necessarily represent the best predictions or potential range of future global and regional health trends; it is p sophisticated causal models incorporating projections of important determinants may provide better predictions for diseases. The preparation of these statistics was undertaken by the WHO Department of Health Statistics and Informatics in c WHO technical programs. Documentation and GBD regional-level summary tables are available on the WHO website (http://www.who.int/evidence/bod). For other queries, please send an email to [email protected]. References 1. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Medicine, 2 2. Murray CJL, Lopez AD, eds. The global burden of disease: a comprehensive assessment of mortality and disability injuries and risk factors in 1990 and projected to 2020. Cambridge, Harvard School of Public Health on behalf of the World Health Organi World Bank, 1996. 3. World Health Organization. The global burden of disease: 2004 update. Geneva, World Health Organization, 2008. 4. 2005 International Comparison Programme preliminary results. Washington, DC, World Bank, 2007. 5. Global economic prospects 2008. Washington, DC, The World Bank, 2008. 6. Asia Pacific Cohort Studies Collaboration. Body mass index and risk of diabetes mellitus in the Asia-Pacific re Pacific Journal of Clinical Nutrition, 2006, 15:127-133. 7. 20. UNAIDS, WHO. Resource needs for AIDS in low- and middle-income countries: estimation process and methods. M Annex II: Revised

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Page 1: [XLS] · Web view951.76 7557.57 37890.50 46705.37 55845.14 15744.90 164747.57 1714528.99 0.38 1.17 2.15 90003.16 492472.67 386293.23 197363.69 55913.32 1222049.77 0.22 1.01 1.16 39686.92

GBD 2004 SUMMARY TABLES

October 2008

Health statistics and informatics Department, World Health Organization,Geneva, Switzerland

http://www.who.int/evidence/bod

NOTES for Tables

a Income categories are as defined by the World Bank's World Development Report 2004. Countries are divided among income groups according to 2004 gross national income (GNI) per capita. The groups are low income (US$825 or less), lower middle income (US$826–3255), upper middle income (US$3256–10 065), and high income (US$10 066 or more). A list of countries and territories by income category is given below.b World totals for males and females include residual populations not included in the World Bank income categories.c For the WHO regions of the Americas, Europe and Western Pacific, these figures include late effects of polio cases with onset prior to regional certification of polio eradication in 1994, 2000 and 2002, respectively. d Does not include liver cancer and cirrhosis resulting from chronic hepatitis virus infection.e This category includes 'Causes arising in the perinatal period' as defined in the International Classification of Diseases, and does not include all conditions occurring in the perinatal period.f Includes severe neonatal infections and other non-infectious causes arising in the perinatal period.g Includes macular degeneration and other age-related causes of vision loss not correctable by provision of glasses or contact lenses, together with deaths due to other sense organ disorders.h Includes myocarditis, pericarditis, endocarditis and cardiomyopathy.

THE GLOBAL BURDEN OF DISEASE: UPDATED PROJECTIONS

This workbook contains summary projections of mortality by cause, sex, age and region. These projections are an update of previous projections released in 2006 (1), and use methods similar to those applied in the original GBD study (2). A set of relatively simple models have been used to project future health trends for baseline, optimistic and pessimistic scenarios, based largely on projections of economic and social development, and using the historically observed relationships of these with cause-specific mortality rates.

These updated projections have been prepared using the GBD 2004 results as a starting-point (3). The methods used are essentially the same as those previously published (1), with the following changes:

(1) Projections of income per capita were revised to take account of World Bank revisions to purchasing power parity (PPP) conversion rates (4) and latest World Bank regional projections of real growth per annum in income per capita (5);(2) Countries for which low-income regression coefficients were used were revised to take account of revised country income levels and projections;(3) The projection regression equations were recalibrated so that back projections of child mortality rates from 2004 to 1990 matched observed trends for World Bank regions. In the recalibrated projections, the regression coefficient for human capital was left unchanged and the regression coefficient for time (a proxy for technological change) was set to zero for low-income countries in the WHO African, European, South East Asia and Western Pacific Regions;(4) Baseline, optimistic and pessimistic projections for HIV incidence and mortality were based on updated UNAIDS projections, incorporating different assumptions about future trends in scale-up of antiretroviral therapy coverage (see below);(5) Relative risks for diabetes mellitus mortality associated with increasing levels of body mass index (kg/m2) were revised downwards based on latest information from the Asia Pacific Cohorts study (6).

Optimistic projections for HIV are based on UNAIDS projections under a "phased scale-up to universal access" scenario, which assumes different rates of scale-up for coverage of antiretroviral treatment (ART) for each country based on current service coverage and capacity, with countries reaching universal access (80% coverage for those "in need of treatment") by 2015 at the latest (7). From 2016 to 2030, coverage is assumed to remain constant and HIV incidence to decrease by around 6% per annum for children and 4.5% per annum for adults.

These projections are less firm than the base year assessments for 2004, and provide “business as usual” projections under specified assumptions that do not specifically take account of trends in major risk factors apart from tobacco smoking, and to a limited extent, overweight and obesity. This spreadsheet includes point estimates for projected deaths by region, cause, age and sex. Explicit uncertainty ranges are not included here, uncertainty in projections is better conveyed through comparison of optimistic and pessimistic scenarios with varying input assumptions. The number of significant figures displayed in worksheet cells in this this Excel workbook do not provide information on uncertainty ranges of projected estimates. The optimistic and pessimistic projection scenarios provide an indication of the sensitivity of the projections to variations in input assumptions regarding projected income per capita, human capital, smoking intensity, and TB and HIV mortality. These scenarios do not necessarily represent the best predictions or potential range of future global and regional health trends; it is possible that more sophisticated causal models incorporating projections of important determinants may provide better predictions for specific diseases.

The preparation of these statistics was undertaken by the WHO Department of Health Statistics and Informatics in collaboration with WHO technical programs. Documentation and GBD regional-level summary tables are available on the WHO website (http://www.who.int/evidence/bod). For other queries, please send an email to [email protected].

References1. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Medicine, 2006, 3(11):e442.2. Murray CJL, Lopez AD, eds. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020. Cambridge, Harvard School of Public Health on behalf of the World Health Organization and the World Bank, 1996.3. World Health Organization. The global burden of disease: 2004 update. Geneva, World Health Organization, 2008.4. 2005 International Comparison Programme preliminary results. Washington, DC, World Bank, 2007.5. Global economic prospects 2008. Washington, DC, The World Bank, 2008.6. Asia Pacific Cohort Studies Collaboration. Body mass index and risk of diabetes mellitus in the Asia-Pacific region. Asian Pacific Journal of Clinical Nutrition, 2006, 15:127-133.7. 20. UNAIDS, WHO. Resource needs for AIDS in low- and middle-income countries: estimation process and methods. Methodological Annex II: Revised projections of the number of people in need of ART. Geneva, Joint United Nations Programme on HIV/AIDS, 2007..

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List of countries in income categories

Income category Countries and territories includedHigh income Andorra

ArubaAustraliaAustriaBahamasBahrainBelgiumBermudaBrunei DarussalamCanadaCayman IslandsChannel IslandsCyprusDenmarkFaeroe IslandsFinlandFranceFrench PolynesiaGermanyGreeceGreenlandGuamIcelandIrelandIsle of ManIsraelItalyJapanKuwaitLiechtensteinLuxembourgMaltaMonacoNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNorwayPortugalPuerto RicoQatarRepublic of KoreaSan MarinoSaudi ArabiaSingaporeSloveniaSpainSwedenSwitzerlandUnited Arab EmiratesUnited KingdomUnited States Virgin IslandsUnited States of America

Upper middle income American SamoaAntigua and BarbudaArgentinaBarbadosBelizeBotswanaChileCosta Rica

NOTES for Tables

a Income categories are as defined by the World Bank's World Development Report 2004. Countries are divided among income groups according to 2004 gross national income (GNI) per capita. The groups are low income (US$825 or less), lower middle income (US$826–3255), upper middle income (US$3256–10 065), and high income (US$10 066 or more). A list of countries and territories by income category is given below.b World totals for males and females include residual populations not included in the World Bank income categories.c For the WHO regions of the Americas, Europe and Western Pacific, these figures include late effects of polio cases with onset prior to regional certification of polio eradication in 1994, 2000 and 2002, respectively. d Does not include liver cancer and cirrhosis resulting from chronic hepatitis virus infection.e This category includes 'Causes arising in the perinatal period' as defined in the International Classification of Diseases, and does not include all conditions occurring in the perinatal period.f Includes severe neonatal infections and other non-infectious causes arising in the perinatal period.g Includes macular degeneration and other age-related causes of vision loss not correctable by provision of glasses or contact lenses, together with deaths due to other sense organ disorders.h Includes myocarditis, pericarditis, endocarditis and cardiomyopathy.

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CroatiaCzech RepublicDominicaEquatorial GuineaEstoniaGabonGrenadaHungaryLatviaLebanonLibyan Arab JamahiriyaLithuaniaMalaysiaMauritiusMexicoNorthern Mariana IslandsOmanPalauPanamaPolandRussian FederationSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSeychellesSlovakiaSouth AfricaTrinidad and TobagoTurkeyUruguayVenezuela (Bolivarian Republic of)

Lower middle income AlbaniaAlgeriaAngolaArmeniaAzerbaijanBelarusBoliviaBosnia and HerzegovinaBrazilBulgariaCape VerdeChinaColombiaCubaDjiboutiDominican RepublicEcuadorEgyptEl SalvadorFijiGeorgiaGuatemalaGuyanaHondurasIndonesiaIran (Islamic Republic of)IraqJamaicaJordanKazakhstanKiribatiMaldivesMarshall IslandsMicronesia (Federated States of)MoroccoNamibiaParaguayPeruPhilippinesRomaniaSamoaSerbia and Montenegro

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Sri LankaSurinameSwazilandSyrian Arab RepublicThailandThe former Yugoslav Republic of MacedoniaTongaTunisiaTurkmenistanUkraineVanuatuWest Bank and Gaza Strip

Low income AfghanistanBangladeshBeninBhutanBurkina FasoBurundiCambodiaCameroonCentral African RepublicChadComorosCongoCôte d'IvoireDemocratic People's Republic of KoreaDemocratic Republic of the CongoEritreaEthiopiaGambiaGhanaGuineaGuinea-BissauHaitiIndiaKenyaKyrgyzstanLao People's Democratic RepublicLesothoLiberiaMadagascarMalawiMaliMauritaniaMongoliaMozambiqueMyanmarNepalNicaraguaNigerNigeriaPakistanPapua New GuineaRepublic of MoldovaRwandaSao Tome and PrincipeSenegalSierra LeoneSolomon IslandsSomaliaSudanTajikistanTimor-LesteTogoUgandaUnited Republic of TanzaniaUzbekistanViet NamYemenZambiaZimbabwe

Not included Anguilla

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British Virgin IslandsCook IslandsFalkland Islands (Malvinas)French GuianaGibraltarGuadeloupeHoly SeeMartiniqueMontserratNauruNiuePitcairnRéunionSaint HelenaSaint Pierre et MiquelonTokelauTurks and Caicos IslandsTuvaluWallis and Futuna IslandsWestern Sahara

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Summary: Projected DALYs (000s) by cause, and income group (a), optimistic scenario 2030

Cause WORLD (b)Population (000) 8 195 881 1 044 862 634 987 2 847 752 3 668 148

(000) % total (000) (000) (000) (000)TOTAL DALYs 1 265 434 100.0 117 355 90 504 399 690 657 868

199 627 15.8 4 090 8 764 29 558 157 211

Infectious and parasitic diseases 84 211 6.7 1 891 5 952 11 156 65 209 Tuberculosis 12 033 1.0 56 616 1 617 9 744 STDs excluding HIV 4 878 0.4 112 267 742 3 756 Syphilis 738 0.1 3 27 71 637 Chlamydia 1 901 0.2 84 126 372 1 320 Gonorrhoea 2 133 0.2 24 110 278 1 720 HIV/AIDS 23 213 1.8 873 4 132 3 142 15 065 Diarrhoeal diseases 14 544 1.1 224 345 2 454 11 521 Childhood diseases 4 615 0.4 20 21 249 4 325 Pertussis 1 463 0.1 17 14 88 1 344 Poliomyelitis (c) 8 0.0 3 0 1 5 Diphtheria 28 0.0 0 0 1 26 Measles 2 201 0.2 0 4 95 2 100 Tetanus 915 0.1 0 2 64 850 Meningitis 2 132 0.2 30 53 287 1 762 Hepatitis B (d) 584 0.0 35 21 184 343 Hepatitis C (d) 302 0.0 69 13 85 135 Malaria 8 917 0.7 13 112 454 8 339 Tropical diseases 3 755 0.3 4 69 301 3 381 Trypanosomiasis 579 0.0 0 1 22 556 Chagas disease 141 0.0 0 39 101 1 Schistosomiasis 643 0.1 3 24 40 576 Leishmaniasis 382 0.0 1 2 27 352 Lymphatic filariasis 1 809 0.1 0 3 110 1 696 Onchocerciasis 201 0.0 0 1 1 200 Leprosy 68 0.0 0 3 8 56 Dengue 62 0.0 1 1 24 36 Japanese encephalitis 109 0.0 1 2 33 73 Trachoma 603 0.0 0 4 162 437 Intestinal nematode infections 1 216 0.1 9 41 291 875 Ascariasis 544 0.0 2 10 89 443 Trichuriasis 247 0.0 2 12 59 174 Hookworm disease 419 0.0 6 19 140 255Respiratory infections 33 282 2.6 1 032 819 4 864 26 567 Lower respiratory infections 32 077 2.5 945 751 4 546 25 834 Upper respiratory infections 792 0.1 48 40 207 497 Otitis media 413 0.0 40 28 110 236Maternal conditions 9 035 0.7 186 259 1 437 7 152 Maternal haemorrhage 985 0.1 1 9 100 874 Maternal sepsis 1 272 0.1 41 37 254 941 Hypertensive disorders 375 0.0 1 14 58 302 Obstructed labour 1 186 0.1 7 31 176 972 Abortion 1 745 0.1 7 52 261 1 425Perinatal conditions (e) 60 722 4.8 609 1 132 9 378 49 602 Prematurity and low birth weight 20 002 1.6 258 456 3 288 15 999 Birth asphyxia and birth trauma 20 288 1.6 165 358 3 407 16 357 Neonatal infections and other conditions (f) 20 433 1.6 186 318 2 683 17 246Nutritional deficiencies 12 377 1.0 372 602 2 723 8 680 Protein-energy malnutrition 5 416 0.4 54 151 914 4 297 Iodine deficiency 1 249 0.1 1 166 319 762 Vitamin A deficiency 141 0.0 0 2 8 131 Iron-deficiency anaemia 5 351 0.4 310 268 1 450 3 323II. Noncommunicable conditions 861 283 68.1 103 846 69 527 308 133 379 765Malignant neoplasms 100 300 7.9 17 030 9 138 39 733 34 398 Mouth and oropharynx cancers 5 208 0.4 391 295 1 195 3 328 Oesophagus cancer 6 450 0.5 473 262 3 354 2 362 Stomach cancer 9 140 0.7 983 838 5 236 2 083 Colon/rectum cancer 6 915 0.5 2 078 906 2 456 1 475 Liver cancer 8 111 0.6 819 304 4 585 2 402 Pancreas cancer 2 546 0.2 844 337 812 552 Trachea/bronchus/lung cancers 19 015 1.5 3 289 1 715 10 048 3 964 Melanoma and other skin cancers 826 0.1 300 136 153 237 Breast cancer 7 914 0.6 1 658 854 2 349 3 052 Cervix uteri cancer 4 902 0.4 182 374 1 029 3 318

HIGH INCOME

UPPER MIDDLE INCOME

LOWER MIDDLE INCOME

LOW INCOME

I. Communicable diseases, maternal and perinatal conditions and nutritional deficiencies

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Cause WORLD (b)Population (000) 8 195 881 1 044 862 634 987 2 847 752 3 668 148

(000) % total (000) (000) (000) (000)

HIGH INCOME

UPPER MIDDLE INCOME

LOWER MIDDLE INCOME

LOW INCOME

Corpus uteri cancer 1 049 0.1 395 222 238 195 Ovary cancer 1 968 0.2 386 226 479 877 Prostate cancer 2 915 0.2 844 374 731 967 Bladder cancer 2 091 0.2 490 223 784 594 Lymphomas, multiple myeloma 5 476 0.4 899 392 1 444 2 741 Leukaemia 4 946 0.4 642 431 1 846 2 027Other neoplasms 2 549 0.2 361 208 756 1 224Diabetes mellitus 27 296 2.2 4 249 3 539 10 059 9 448Nutritional/endocrine disorders 9 230 0.7 1 530 728 2 714 4 258Neuropsychiatric disorders 234 314 18.5 33 706 18 967 79 134 102 504 Unipolar depressive disorders 85 307 6.7 10 360 5 910 27 441 41 596 Bipolar affective disorder 15 185 1.2 1 421 1 079 4 963 7 721 Schizophrenia 18 084 1.4 1 455 1 272 6 271 9 087 Epilepsy 7 288 0.6 476 591 1 999 4 222 Alcohol use disorders 25 475 2.0 4 041 3 023 11 604 6 806 Alzheimer and other dementias 19 502 1.5 6 809 1 728 7 162 3 804 Parkinson disease 2 078 0.2 808 121 649 499 Multiple sclerosis 1 684 0.1 292 137 551 703 Drug use disorders 9 729 0.8 1 846 766 2 896 4 222 Post-traumatic stress disorder 4 277 0.3 495 309 1 417 2 056 Obsessive-compulsive disorder 6 339 0.5 576 669 1 898 3 196 Panic disorder 7 683 0.6 757 556 2 462 3 907 Insomnia (primary) 4 958 0.4 805 436 1 353 2 364 Migraine 7 627 0.6 1 337 616 2 407 3 268Sense organ disorders 123 425 9.8 10 727 7 430 45 104 60 164 Glaucoma 8 428 0.7 490 702 3 477 3 760 Cataracts 23 085 1.8 447 1 246 8 660 12 732 Refractive errors 36 180 2.9 2 895 1 571 13 591 18 123 Hearing loss, adult onset 40 032 3.2 5 005 2 769 13 481 18 777 Macular degeneration and other (g) 15 701 1.2 1 891 1 143 5 895 6 772Cardiovascular diseases 165 078 13.0 16 373 14 953 57 980 75 768 Rheumatic heart disease 3 914 0.3 101 134 1 209 2 470 Hypertensive heart disease 9 533 0.8 848 694 4 590 3 401 Ischaemic heart disease 69 424 5.5 7 307 7 017 20 149 34 951 Cerebrovascular disease 54 617 4.3 4 290 4 978 23 922 21 428 Inflammatory heart disease (h) 5 575 0.4 566 412 1 631 2 966Respiratory diseases 77 868 6.2 5 895 3 865 32 187 35 919 Chronic obstructive pulmonary disease 46 647 3.7 2 533 1 545 22 525 20 044 Asthma 18 637 1.5 1 863 1 383 5 318 10 072Digestive diseases 31 177 2.5 4 235 3 082 8 969 14 890 Peptic ulcer disease 4 196 0.3 191 247 1 090 2 668 Cirrhosis of the liver 10 550 0.8 1 431 1 298 3 444 4 377 Appendicitis 319 0.0 24 24 85 186Diseases of the genitourinary system 17 118 1.4 1 433 1 148 6 191 8 346 Nephritis/nephrosis 9 962 0.8 722 631 3 171 5 438 Benign prostatic hypertrophy 4 287 0.3 378 331 1 717 1 860Skin diseases 5 349 0.4 296 441 1 747 2 865Musculoskeletal diseases 40 201 3.2 6 014 3 917 15 681 14 588 Rheumatoid arthritis 6 415 0.5 1 045 730 2 391 2 249 Osteoarthritis 22 007 1.7 3 388 2 305 8 752 7 561Congenital abnormalities 16 091 1.3 1 063 1 058 3 668 10 302Oral diseases 11 287 0.9 933 1 053 4 210 5 090 Dental caries 6 137 0.5 532 572 2 169 2 863 Periodontal disease 456 0.0 36 36 112 272 Edentulism 4 546 0.4 356 437 1 885 1 868III. Injuries 204 524 16.2 9 419 12 213 61 998 120 892Unintentional injuries 149 110 11.8 5 589 5 892 44 273 93 355 Road traffic accidents 81 810 6.5 2 379 2 774 26 059 50 597 Poisoning 5 123 0.4 439 326 873 3 485 Falls 11 660 0.9 1 112 655 3 893 6 001 Fires 8 116 0.6 125 208 951 6 832 Drowning 7 214 0.6 174 215 2 162 4 662 Other unintentional injuries 35 188 2.8 1 360 1 715 10 334 21 778Intentional injuries 55 414 4.4 3 830 6 320 17 726 27 537 Self-inflicted 20 571 1.6 2 891 1 868 5 591 10 220 Violence 26 389 2.1 862 4 154 9 161 12 212 War and civil conflict 8 029 0.6 51 259 2 834 4 886

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05/08/2023 + ^

GBD 2004: Projected DALYs by age, sex and cause for the year 2030, optimistic scenarioWorld (b)

Male FemaleCode Cause Total 0-4 5-14 15-29 30-44 45-59 60-69 70-79 80+ Total 0-4 5-14 15-29 30-44 45-59U000 All Causes 1265 434 160 91 673 012 37 373 249 127 583 199 133 507 436 144 847 548 83 794 936 48 533 796 20 850 606 688 163 783 74 076 515 31 195 132 94 620 189 95 180 586 106 569 598

U001 I.199 627 246 63 931 027 5 675 404 9 385 260 13 557 509 7 969 196 3 208 116 1 976 825 997 704 106 701 041 49 362 767 5 085 511 14 597 004 13 155 348 4 990 643

U002 A. Infectious and parasitic diseases 84 210 765 16 029 470 3 560 375 7 677 977 11 404 076 5 915 035 1 734 624 785 161 279 906 47 386 625 11 344 314 2 919 926 7 078 065 9 417 008 3 564 351

U003 1. Tuberculosis 12 033 351 287 936 262 459 1 864 634 2 803 342 1 666 741 476 102 158 426 37 244 7 556 885 280 538 287 667 1 449 848 1 363 441 671 418

U004 2. STDs excluding HIV 4 877 982 505 178 12 560 702 276 362 042 86 039 36 706 25 518 10 574 1 740 893 405 234 40 708 2 003 744 587 899 57 061

U005 a. Syphilis 738 179 214 628 1 084 73 509 51 476 44 858 30 686 19 612 7 697 443 550 154 005 1 248 71 491 43 922 3 198

U006 b. Chlamydia 1 900 995 715 3 320 155 396 40 634 1 130 139 0 0 201 334 628 28 694 1 372 734 256 820 35 052

U007 c. Gonorrhoea 2 132 580 286 185 8 132 472 421 256 713 4 529 538 0 0 1 028 519 247 996 10 743 557 905 281 963 4 002

U008 d. Other STDs 106 229 3 650 24 950 13 219 35 522 5 343 5 906 2 876 67 490 2 605 23 1 615 5 195 14 809

U009 3. HIV/AIDS 23 212 781 615 183 755 907 2 538 543 5 131 551 1 855 787 487 995 43 878 2 384 11 431 228 622 541 801 591 2 224 153 6 249 628 1 544 871

U010 4. Diarrhoeal diseases 14 544 293 5 885 805 529 199 526 749 651 527 498 690 218 325 141 232 70 969 8 522 496 4 136 958 410 950 403 455 322 099 309 559

U011 5. Childhood-cluster diseases 4 615 117 2 705 829 70 067 31 189 28 723 14 982 4 703 1 609 725 2 857 826 1 670 485 50 152 12 929 12 993 4 939

U012 a. Pertussis 1 462 954 855 162 7 352 798 9 5 127 4 2 863 458 591 449 7 265 421 356 0

U013 b. Poliomyelitis (c) 8 307 1 236 26 990 588 1 090 334 492 295 5 051 1 076 20 27 367 518

U014 c. Diphtheria 27 655 14 610 832 204 37 491 70 5 59 16 308 9 982 1 180 77 34 34

U015 d. Measles 2 200 773 1 249 897 56 317 10 345 11 19 3 0 7 1 316 599 838 752 38 585 6 413 303 0

U016 e. Tetanus 915 428 584 924 5 540 18 852 28 079 13 376 4 169 1 109 361 656 410 229 227 3 101 5 990 11 933 4 386

U017 6. Meningitis 2 132 098 538 003 182 599 201 047 162 931 134 278 36 374 24 078 7 682 1 286 992 380 256 195 263 111 310 48 230 57 921

U018 7. Hepatitis B (d) 583 846 31 985 4 772 50 674 125 095 160 313 38 609 18 819 5 521 435 788 23 903 3 536 21 420 20 966 35 607

U019 Hepatitis C (d) 302 196 12 839 1 807 18 262 54 998 85 777 21 884 12 665 3 482 211 714 9 628 1 376 8 347 10 161 22 910

U020 8. Malaria 8 917 305 4 285 682 419 136 218 813 179 872 99 351 21 854 9 384 2 130 5 236 223 2 993 505 307 069 160 054 116 338 70 311

U021 9. Tropical-cluster diseases 3 754 758 108 828 537 871 949 360 789 882 396 382 60 382 21 540 4 268 2 868 512 72 583 178 972 226 998 167 588 185 041

U022 a. Trypanosomiasis 578 736 15 358 120 899 108 020 103 348 67 618 4 035 1 603 108 420 988 11 510 44 497 44 300 34 071 21 064

U023 b. Chagas disease 140 718 7 12 32 883 17 220 18 234 9 395 4 995 1 687 84 432 12 13 23 502 5 799 11 942

U024 c. Schistosomiasis 642 592 37 172 111 613 61 152 122 413 79 552 25 088 7 088 857 444 936 21 600 58 589 25 942 46 255 29 359

U025 d. Leishmaniasis 381 808 14 383 62 332 92 795 79 458 26 870 5 932 2 069 137 283 975 9 385 26 887 32 539 14 930 8 973

U026 e. lymphatic filariasis 1 809 474 38 418 236 757 633 420 419 022 156 471 7 129 2 255 423 1 493 895 27 739 44 146 88 368 48 276 97 111

U027 f. Onchocerciasis 201 429 3 491 6 258 21 090 48 421 47 637 8 802 3 531 1 056 140 285 2 337 4 840 12 348 18 257 16 592

U028 10. Leprosy 67 666 959 6 873 7 219 12 178 8 533 3 035 2 897 439 42 133 702 6 472 5 996 6 296 4 125

U029 11. Dengue 61 841 6 246 23 865 1 326 1 554 746 281 228 131 34 378 3 630 20 645 1 120 872 515

U030 12. Japanese encephalitis 108 585 18 850 23 008 6 735 4 172 1 396 520 601 268 55 549 15 023 28 526 4 639 2 155 1 028

U031 13. Trachoma 603 366 178 250 5 591 50 109 68 761 37 577 21 640 5 758 189 864 248 491 7 290 80 052 124 245

U032 14. Intestinal nematode infections 1 216 020 100 166 393 648 67 848 60 252 36 333 11 953 5 431 1 633 677 264 84 277 317 198 49 092 38 174 28 476

U033 a. Ascariasis 543 835 66 933 232 704 296 98 26 1 21 62 300 142 56 371 186 858 34 334 8

U034 b. Trichuriasis 246 751 30 961 104 930 23 169 13 5 2 1 136 103 26 315 84 254 16 13 11

U035 c. Hookworm disease 419 017 43 55 530 67 335 59 747 35 823 11 652 5 262 1 521 236 914 31 45 910 48 945 37 763 28 384

U036 Other intestinal infections 6 417 2 230 485 193 237 471 294 146 49 4 105 1 559 175 97 63 74

U037 Other infectious diseases 7 213 095 928 659 344 133 488 173 986 799 801 041 278 397 297 330 126 727 4 251 258 646 752 286 728 388 397 390 619 446 427

U038 B. Respiratory infections 33 282 244 10 774 232 1 408 084 1 071 855 1 573 531 1 603 742 1 295 836 1 066 860 657 400 19 451 540 7 705 240 1 246 837 686 892 633 642 830 879

U039 1. Lower respiratory infections 32 076 888 10 594 074 1 203 179 999 692 1 497 065 1 539 784 1 261 029 1 045 380 644 904 18 785 108 7 562 680 1 077 723 622 806 573 681 791 845

U040 2. Upper respiratory infections 792 259 130 015 49 440 61 262 70 470 58 771 33 346 21 100 12 221 436 625 100 527 44 243 55 584 55 360 36 650

U041 3. Otitis media 413 097 50 143 155 464 10 901 5 995 5 187 1 461 380 275 229 807 42 034 124 871 8 502 4 601 2 384

U042 C. Maternal conditions 9 034 690 0 0 0 0 0 0 0 0 0 0 341 842 6 118 853 2 528 629 45 366

U043 1. Maternal haemorrhage 984 710 0 0 0 0 0 0 0 0 0 0 209 534 500 438 637 11 363

U044 2. Maternal sepsis 1 272 308 0 0 0 0 0 0 0 0 0 0 1 866 935 758 330 989 3 695

U045 3. Hypertensive disorders 375 169 0 0 0 0 0 0 0 0 0 0 11 583 230 182 129 196 4 209

U046 4. Obstructed labour 1 186 084 0 0 0 0 0 0 0 0 0 0 0 870 133 312 895 3 056

U047 5. Abortion 1 744 638 0 0 0 0 0 0 0 0 0 0 321 778 1 242 019 180 626 215

U048 Other maternal conditions 3 471 781 0 0 0 0 0 0 0 0 0 0 6 405 2 306 260 1 136 287 22 828

U049 D. Perinatal conditions (e) 60 722 271 33 445 879 938 279 182 72 46 16 5 33 447 417 27 273 872 538 256 98 51

U050 1. Prematurity and low birth weight 20 001 904 11 052 872 169 55 8 3 7 0 0 11 053 113 8 948 628 137 24 0 0

U051 2. Birth asphyxia and birth trauma 20 287 577 10 986 847 428 133 107 42 30 16 5 10 987 608 9 299 640 159 99 40 13

U052 3. 20 432 790 11 406 159 342 91 68 27 9 0 0 11 406 696 9 025 605 242 133 59 38

U053 E. Nutritional deficiencies 12 377 277 3 681 447 706 007 635 149 579 720 450 347 177 610 124 788 60 392 6 415 460 3 039 341 576 368 712 938 575 970 549 996

U054 1. Protein-energy malnutrition 5 416 100 2 685 171 94 664 46 575 75 219 49 082 12 548 15 434 12 881 2 991 575 2 206 457 83 300 20 115 26 867 29 649

U055 2. Iodine deficiency 1 248 632 534 833 135 235 45 32 383 65 83 21 670 696 462 624 113 959 265 232 297

U056 3. Vitamin A deficiency 141 016 72 233 8 462 362 151 225 66 52 34 81 586 54 602 4 089 88 267 162

U057 4. Iron-deficiency anaemia 5 351 367 363 033 461 319 578 092 481 985 373 944 156 133 96 014 42 016 2 552 537 296 257 368 085 685 992 540 201 504 994U058 Other nutritional disorders 220 162 26 178 6 326 10 074 22 332 26 713 8 799 13 205 5 439 119 066 19 400 6 935 6 477 8 403 14 894

Communicable, maternal, perinatal and nutritional conditions

Neonatal infections and other conditions (f)

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U059 II. Noncommunicable diseases 861 283 123 18 629 963 16 942 063 66 530 383 81 693 672 120 282 516 76 015 883 44 330 536 19 014 008 443 439 022 17 094 449 16 633 587 61 799 072 68 407 974 92 139 837

U060 A. Malignant neoplasms 100 300 003 644 961 1 085 606 2 535 743 5 678 283 17 723 801 15 520 994 8 892 340 2 930 838 55 012 566 744 827 907 082 1 907 775 6 043 178 14 162 671

U061 1. Mouth and oropharynx cancers 5 208 007 5 637 20 826 167 474 481 349 1 529 024 971 934 415 166 127 716 3 719 126 17 445 15 324 36 985 152 821 521 104

U062 2. Oesophagus cancer 6 450 359 1 653 3 250 33 959 304 420 1 499 034 1 498 305 720 018 170 946 4 231 585 1 251 2 310 34 096 193 959 691 125

U063 3. Stomach cancer 9 140 345 2 420 11 291 123 281 525 728 2 109 594 1 822 213 1 020 016 356 285 5 970 829 698 4 511 91 013 402 587 879 353

U064 4. Colon and rectum cancers 6 914 998 801 11 667 153 813 482 083 1 135 595 1 004 014 715 435 313 981 3 817 387 547 3 960 53 857 370 587 826 508

U065 5. Liver cancer 8 110 640 31 020 26 424 199 106 802 094 2 238 267 1 633 808 729 952 158 841 5 819 512 34 981 19 387 131 158 297 145 625 530

U066 6. Pancreas cancer 2 545 505 897 2 384 7 370 133 224 489 365 423 279 264 864 92 835 1 414 219 102 731 12 237 88 515 279 433

U067 7. Trachea, bronchus, lung cancers 19 015 484 2 9 6 919 737 4 689 635 4 591 875 2 275 938 462 071 12 939 273 5 44 5 481 603 1 902 794

U068 8. Melanoma and other skin cancers 826 414 990 2 109 26 260 63 267 156 606 95 219 65 947 32 991 443 388 1 594 3 997 19 694 61 516 113 016

U069 9. Breast cancer 7 913 885 6 15 181 1 442 5 551 4 580 3 802 1 985 17 563 761 5 336 82 787 1 544 372 3 242 010

U070 10. Cervix uteri cancer 4 901 972 0 0 0 0 0 0 0 0 0 166 2 658 531 472 564 873 1 971 367

U071 11. Corpus uteri cancer 1 049 015 0 0 0 0 0 0 0 0 0 4 187 5 776 11 050 107 374 369 722

U072 12. Ovary cancer 1 968 415 0 0 0 0 0 0 0 0 0 2 698 37 304 126 462 319 029 656 161

U073 13. Prostate cancer 2 915 041 910 2 416 4 117 18 256 415 995 899 198 1 056 155 517 995 2 915 041 0 0 0 0 0

U074 14. Bladder cancer 2 091 490 2 168 2 755 17 099 77 930 395 279 461 882 389 556 193 561 1 540 230 2 023 1 034 7 622 52 052 117 221

U075 15. Lymphomas, multiple myeloma 5 475 731 106 878 386 298 543 004 626 391 750 794 507 851 315 049 123 242 3 359 508 85 218 241 233 220 440 299 160 422 091

U076 16. Leukaemia 4 945 506 185 930 367 088 912 033 405 637 406 962 293 530 191 054 80 512 2 842 746 214 290 322 009 392 738 349 816 362 543

U077 Other malignant neoplasms 10 827 196 305 648 249 075 348 039 836 725 1 902 099 1 313 307 729 389 297 877 5 982 160 378 862 241 468 156 159 757 771 1 182 691

U078 B. Other neoplasms 2 549 258 65 678 105 680 220 944 234 773 281 673 184 258 137 928 65 420 1 296 355 75 390 139 865 109 158 231 800 305 258

U079 C. Diabetes mellitus 27 295 918 30 236 52 395 525 286 2 203 958 4 872 589 2 840 295 1 547 042 558 448 12 630 249 27 162 56 474 368 845 2 155 919 4 715 990

U080 D. Endocrine disorders 9 230 255 858 078 215 337 577 533 837 716 1 084 053 527 290 328 850 159 984 4 588 841 657 523 207 896 613 742 725 049 1 043 083

U081 E. Neuropsychiatric conditions 234 314 100 4 703 801 8 421 323 45 142 561 27 394 926 14 413 984 4 927 366 3 565 047 2 419 049 110 988 059 4 597 242 8 457 628 45 409 957 28 290 506 16 958 694

U082 1. Unipolar depressive disorders 85 307 379 120 2 942 420 10 315 270 9 915 730 5 645 999 1 471 090 235 016 63 859 30 589 503 79 3 051 413 16 717 278 18 327 989 11 879 347

U083 2. Bipolar disorder 15 185 007 89 394 098 6 425 583 829 644 24 893 5 942 494 84 7 680 827 69 301 859 6 304 031 857 275 30 174

U084 3. Schizophrenia 18 084 240 432 1 149 536 6 607 173 952 950 259 354 45 230 16 345 5 204 9 036 224 317 313 628 6 803 766 1 442 627 371 566

U085 4. Epilepsy 7 287 956 300 903 802 524 1 259 550 922 917 508 352 154 873 62 839 19 450 4 031 409 281 922 704 622 1 028 676 630 813 370 002

U086 5. Alcohol use disorders 25 474 593 1 532 625 620 8 431 082 8 536 860 4 330 361 610 178 98 412 21 301 22 655 345 13 199 91 280 1 133 733 882 264 578 743

U087 6. Alzheimer and other dementias 19 501 641 229 141 113 837 139 116 102 529 468 186 1 564 346 2 373 928 1 967 651 6 958 734 212 666 111 236 134 485 102 765 532 421

U088 7. Parkinson disease 2 077 584 3 157 1 906 11 175 74 889 270 701 272 027 291 698 143 281 1 068 835 2 142 2 230 3 522 53 404 218 737

U089 8. Multiple sclerosis 1 683 723 394 68 464 313 211 236 540 74 373 20 341 7 369 2 335 723 027 454 91 178 402 389 314 902 102 752

U090 9. Drug use disorders 9 729 499 224 170 726 4 201 576 2 534 363 756 989 32 330 3 710 951 7 700 870 151 89 560 1 116 088 631 066 179 299

U091 10. Post-traumatic stress disorder 4 277 253 8 37 246 556 443 376 007 186 556 4 455 2 257 831 1 163 803 5 27 431 1 504 176 1 042 312 501 461

U092 11. Obsessive-compulsive disorder 6 338 849 0 257 729 1 472 065 713 682 197 500 33 379 8 534 1 878 2 684 767 0 591 712 1 539 451 1 083 017 354 265

U093 12. Panic disorder 7 683 284 0 117 097 2 322 093 30 149 105 972 11 580 5 705 819 2 593 415 0 120 332 4 637 378 48 346 233 488

U094 13. Insomnia (primary) 4 957 918 0 43 325 652 593 732 921 433 984 185 104 56 210 14 864 2 119 002 0 47 281 637 599 923 247 696 785

U095 14. Migraine 7 626 842 70 811 808 630 1 051 480 153 560 9 201 340 77 3 2 094 104 163 762 2 274 499 2 292 591 793 341 7 903

U096 15. Mental retardation, lead-caused 5 971 505 2 993 988 11 107 24 422 9 914 4 731 1 638 857 180 3 046 836 2 892 892 10 462 8 037 6 262 4 089

Other neuropsychiatric disorders 13 126 828 1 103 002 877 059 1 359 728 1 272 271 1 136 831 514 514 401 596 176 357 6 841 358 1 029 583 628 904 1 146 758 1 150 877 897 663

U098 F. Sense organ diseases 123 425 482 248 847 1 672 881 3 517 176 14 453 125 19 399 767 12 703 009 4 749 559 1 019 124 57 763 487 215 771 1 442 580 2 732 127 13 764 594 20 859 754

U099 1. Glaucoma 8 427 897 19 384 65 529 243 790 734 063 1 271 568 727 240 312 983 105 855 3 480 413 4 047 22 165 224 352 870 184 1 695 432

U100 2. Cataracts 23 085 495 10 873 71 804 472 468 2 315 495 4 466 439 2 311 015 1 019 752 280 029 10 947 874 8 370 39 786 330 427 2 021 227 4 478 020

U101 3. Refractive errors 36 179 784 214 012 1 511 342 1 677 629 3 714 618 4 144 373 4 540 892 1 487 604 198 975 17 489 445 198 937 1 367 094 1 443 764 3 278 975 4 153 148

U102 4. Hearing loss, adult onset 40 031 566 0 0 920 838 6 468 500 6 969 967 3 619 106 1 313 964 225 830 19 518 204 0 0 534 456 6 205 514 7 055 533

U103 5. Macular degeneration and other (g) 15 700 741 4 578 24 205 202 452 1 220 449 2 547 420 1 504 756 615 257 208 434 6 327 552 4 417 13 535 199 129 1 388 693 3 477 621

U104 G. Cardiovascular diseases 165 077 794 1 087 412 561 147 3 460 793 11 915 710 27 983 019 21 293 221 15 243 389 7 652 753 89 197 444 977 072 470 128 1 837 648 4 894 346 14 129 119

U105 1. Rheumatic heart disease 3 914 345 102 221 64 897 353 469 518 988 551 210 256 072 142 122 49 307 2 038 286 98 501 61 631 186 915 261 649 424 473

U106 2. Hypertensive heart disease 9 533 291 20 469 15 247 97 397 528 260 1 452 413 1 262 973 1 006 578 539 558 4 922 894 19 309 14 612 44 369 200 122 718 441

U107 3. Ischaemic heart disease 69 424 189 50 258 45 846 829 126 5 330 757 14 768 011 9 878 720 6 433 606 2 845 067 40 181 390 42 799 19 128 433 318 1 732 260 6 177 605

U108 4. Cerebrovascular disease 54 617 076 180 730 126 045 892 566 2 754 399 8 041 750 7 593 726 5 676 431 2 692 329 27 957 977 149 399 113 571 485 986 1 592 614 4 472 264

U109 5. Inflammatory heart diseases (h) 5 574 855 219 897 50 817 417 642 792 616 667 289 509 634 373 623 196 578 3 228 096 184 149 37 837 155 440 284 048 425 739U110 Other cardiovascular diseases 22 014 039 513 837 258 295 870 593 1 990 690 2 502 346 1 792 096 1 611 030 1 329 915 10 868 802 482 916 223 350 531 621 823 654 1 910 597

U111 H. Respiratory diseases 77 867 592 1 668 462 2 507 220 4 458 429 6 270 238 14 174 284 9 955 237 6 147 130 2 749 889 47 930 890 1 357 557 2 746 447 3 220 160 2 732 632 5 472 344

U112 1. Chronic obstructive pulmonary disease 46 646 684 27 479 33 134 154 689 3 082 823 10 958 156 8 409 786 5 097 703 2 190 578 29 954 349 21 615 15 900 118 329 1 189 053 3 717 622

U113 2. Asthma 18 636 619 1 108 432 2 200 979 3 538 206 1 638 478 1 372 601 403 013 199 687 73 576 10 534 971 853 341 2 559 189 2 427 623 734 449 856 633

U114 Other respiratory diseases 12 584 289 532 552 273 106 765 535 1 548 937 1 843 527 1 142 439 849 739 485 734 7 441 570 482 600 171 359 674 209 809 130 898 090

U115 I. Digestive diseases 31 176 757 432 963 363 830 1 655 779 5 249 608 7 568 504 2 600 202 1 330 643 511 215 19 712 743 412 072 259 913 1 181 002 2 172 741 3 169 584

U116 1. Peptic ulcer disease 4 196 103 12 450 70 658 256 528 852 277 1 131 862 346 806 209 240 81 935 2 961 758 28 404 10 828 92 461 238 644 360 287

U117 2. Cirrhosis of the liver 10 550 015 64 045 95 375 309 920 1 727 391 3 508 465 1 174 870 490 723 110 292 7 481 081 67 625 51 350 192 371 495 698 1 032 758

U118 3. Appendicitis 319 161 1 203 25 023 43 083 43 810 61 274 20 338 12 457 5 337 212 525 1 082 12 237 15 387 15 991 20 676

U119 Other digestive diseases 16 111 478 355 264 172 774 1 046 247 2 626 130 2 866 902 1 058 187 618 223 313 651 9 057 380 314 960 185 498 880 783 1 422 408 1 755 863

U120 J. Genitourinary diseases 17 118 031 238 725 187 310 769 474 1 569 001 5 479 951 1 661 773 1 038 501 532 834 11 477 569 224 347 135 791 429 999 856 340 1 526 946

U121 1. Nephritis and nephrosis 9 962 424 188 789 165 039 589 263 1 279 413 1 621 912 1 008 076 656 640 329 807 5 838 939 185 230 118 516 264 809 538 595 1 124 352

U122 2. Benign prostatic hypertrophy 4 286 584 0 0 56 17 974 3 509 703 426 781 225 496 106 574 4 286 584 0 0 0 0 0

U123 Other genitourinary system diseases 2 869 022 49 936 22 272 180 156 271 614 348 336 226 916 156 365 96 452 1 352 046 39 117 17 275 165 190 317 746 402 594

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U124 K. Skin diseases 5 348 814 245 828 299 249 596 704 618 967 461 417 198 016 127 299 79 428 2 626 907 166 818 189 444 512 533 563 891 569 131

U125 L. Musculoskeletal diseases 40 200 976 124 523 581 255 1 928 833 4 648 416 5 402 265 2 465 286 1 024 815 294 677 16 470 070 97 036 762 553 2 481 999 5 379 598 7 637 250

U126 1. Rheumatoid arthritis 6 415 073 12 136 111 101 289 709 433 439 562 282 259 477 111 380 34 225 1 813 750 23 669 274 240 761 990 1 092 289 1 442 042

U127 2. Osteoarthritis 22 006 604 144 4 004 561 267 2 101 536 3 130 916 1 653 185 643 636 128 311 8 222 999 107 6 920 910 591 3 120 987 4 922 336

U128 3. Gout 3 006 773 12 331 127 729 1 371 535 931 556 168 339 43 815 14 174 2 657 491 14 99 25 646 143 122 99 191

U129 4. Low back pain 3 073 953 82 695 271 709 357 370 403 533 341 066 95 909 33 274 9 976 1 595 532 43 355 329 155 245 681 392 113 314 544

U130 Other musculoskeletal disorders 5 698 573 29 537 194 109 592 757 338 373 436 445 288 376 192 710 107 992 2 180 298 29 892 152 139 538 091 631 087 859 137

U131 M. Congenital anomalies 16 091 004 7 838 382 156 884 291 418 98 471 60 887 20 360 13 211 6 163 8 485 775 7 127 979 153 359 161 651 69 525 53 793

U132 1. Abdominal wall defect 95 194 51 322 250 449 184 81 9 24 29 52 348 42 185 301 176 73 26

U133 2. Anencephaly 306 201 158 299 842 1 777 486 228 45 65 86 161 828 141 781 1 232 798 273 98

U134 3. Anorectal atresia 35 807 18 704 217 509 92 30 9 10 4 19 574 15 684 170 245 38 16

U135 4. Cleft lip 146 027 70 339 237 1 364 2 337 3 247 2 021 1 575 756 81 876 64 091 55 3 1 1

U136 5. Cleft palate 144 040 72 824 44 136 142 12 19 12 7 73 196 70 486 67 14 26 248

U137 6. Oesophageal atresia 25 313 13 361 227 329 98 55 13 15 13 14 111 10 370 365 234 79 91

U138 7. Renal agenesis 41 633 23 533 230 314 191 563 364 29 36 25 260 14 738 347 574 281 219

U139 8. Down syndrome 3 910 322 2 016 184 18 445 51 677 6 997 10 296 3 166 383 133 2 107 281 1 735 952 16 171 29 656 5 963 11 731

U140 9. Congenital heart anomalies 7 553 028 3 573 550 79 950 166 007 52 021 22 566 6 974 5 972 2 646 3 909 686 3 402 250 78 807 90 039 34 900 20 299

U141 10. Spina bifida 1 014 951 497 589 8 716 7 551 2 104 1 128 281 106 109 517 584 484 701 4 810 3 865 2 510 898

U142 Other Congenital anomalies 2 818 489 1 342 677 47 725 61 305 33 819 22 682 7 458 5 020 2 344 1 523 031 1 145 741 51 035 36 048 25 381 20 169

U143 N. Oral conditions 11 287 138 442 065 731 947 849 708 520 479 1 376 323 1 118 575 184 781 34 188 5 258 066 413 652 704 428 832 476 527 853 1 536 220

U144 1. Dental caries 6 136 844 429 435 729 687 701 154 324 227 528 622 206 371 79 258 26 347 3 025 100 401 293 700 103 678 539 324 284 572 238

U145 2. Periodontal disease 456 237 0 31 56 126 110 144 39 502 11 248 4 422 1 602 223 075 0 856 54 000 110 330 43 455

U146 3. Edentulism 4 545 553 0 0 82 588 68 549 798 108 896 259 97 142 4 331 1 946 978 0 0 84 740 73 267 904 516

U147 Other oral diseases 148 504 12 630 2 229 9 840 17 558 10 091 4 698 3 959 1 908 62 913 12 359 3 468 15 197 19 972 16 011

U148 III.Injuries 204 523 791 9 112 022 14 755 783 51 667 558 38 256 255 16 595 836 4 570 938 2 226 435 838 894 138 023 720 7 619 298 9 476 034 18 224 115 13 617 265 9 439 117

U149 A. Unintentional injuries 149 110 209 8 648 888 13 008 109 31 538 393 24 828 525 12 179 940 3 274 177 1 770 593 688 963 95 937 588 7 227 454 8 502 177 14 012 245 9 902 425 6 860 626

U150 1. Road traffic accidents 81 809 746 2 790 622 6 772 530 23 281 462 14 575 436 6 757 777 1 596 333 670 038 174 943 56 619 142 2 550 345 4 660 182 7 933 394 5 101 433 3 338 354

U151 2. Poisonings 5 122 815 369 138 198 220 506 626 1 016 826 709 258 165 258 60 124 20 315 3 045 766 203 833 131 592 337 847 426 307 382 359

U152 3. Falls 11 660 395 705 424 1 176 248 1 137 586 1 448 268 994 576 451 367 455 728 259 771 6 628 968 587 975 853 409 734 049 614 541 530 420

U153 4. Fires 8 115 759 965 530 565 751 487 899 885 663 342 506 76 358 53 186 21 125 3 398 018 961 985 464 679 1 304 118 1 086 095 494 837

U154 5. Drownings 7 213 724 889 633 979 734 1 044 274 1 370 469 603 536 129 603 69 067 24 990 5 111 306 569 978 371 022 381 108 233 354 228 423

U155 6. Other unintentional injuries 35 187 770 2 928 541 3 315 625 5 080 546 5 531 862 2 772 288 855 258 462 449 187 818 21 134 388 2 353 338 2 021 293 3 321 728 2 440 695 1 886 233

U156 B. Intentional injuries 55 413 583 463 134 1 747 674 20 129 165 13 427 730 4 415 896 1 296 760 455 842 149 931 42 086 132 391 844 973 857 4 211 870 3 714 840 2 578 491

U157 1. Self-inflicted injuries 20 570 590 0 311 831 5 381 783 4 110 532 1 955 955 837 235 328 260 99 615 13 025 211 0 318 393 2 408 216 2 082 295 1 647 085

U158 2. Violence 26 388 884 383 038 988 445 11 440 987 6 743 794 1 904 046 354 496 104 207 40 436 21 959 450 306 978 336 585 1 550 908 1 251 920 694 815

U159 3. War and civil conflict 8 028 975 79 132 428 840 3 121 417 2 464 694 526 557 90 512 18 369 7 915 6 737 436 79 603 314 421 238 972 367 883 221 635

U160 Other intentional injuries 425 133 964 18 558 184 978 108 709 29 338 14 518 5 006 1 965 364 035 5 263 4 457 13 774 12 741 14 956

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Female60-69 70-79 80+ Total

78 038 321 66 651 204 30 938 832 577 270 377

2 272 696 2 242 280 1 219 956 92 926 205

1 220 101 955 976 324 400 36 824 140 283 935 115 316 24 304 4 476 467 23 423 14 290 4 731 3 137 089 9 470 8 699 2 598 294 630 5 706 26 0 1 699 661 1 355 95 2 1 104 060 6 892 5 469 2 131 38 738

233 582 104 670 517 11 781 553 185 387 167 693 85 696 6 021 798

1 738 3 114 942 1 757 291 0 4 0 599 496

384 613 251 3 256 9 16 14 11 346

42 0 78 884 174 1 303 2 481 598 259 019

24 829 21 436 5 862 845 106 18 100 18 632 5 892 148 058 14 910 18 072 5 078 90 482 20 109 11 342 2 353 3 681 083 34 059 17 471 3 535 886 246 1 517 743 47 157 748 6 762 6 354 1 902 56 286

11 515 4 023 372 197 656 3 701 1 343 76 97 833 6 549 2 865 525 315 580 4 016 2 142 614 61 144

737 917 287 25 533 282 262 138 27 464 558 775 332 53 035

102 014 78 872 20 290 413 503 11 967 7 440 2 132 538 756

53 35 0 243 693 5 33 1 110 648

11 786 7 204 2 081 182 103 124 169 50 2 312

264 618 375 878 162 418 2 961 837 827 110 1 096 985 803 120 13 830 704 801 251 1 077 597 784 198 13 291 781 25 237 19 245 18 788 355 634

622 142 135 183 290 0 0 0 9 034 690 0 0 0 984 710 0 0 0 1 272 308 0 0 0 375 169 0 0 0 1 186 084 0 0 0 1 744 638 0 0 0 3 471 781

29 5 3 27 274 854

0 0 2 8 948 791

18 0 0 9 299 969

11 5 1 9 026 094 225 456 189 315 92 432 5 961 817 13 244 23 475 21 416 2 424 525

146 343 69 577 936 34 120 67 59 430

201 685 141 503 60 113 2 798 830 10 347 23 873 10 767 101 096

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71 280 073 61 803 739 28 685 369 417 844 10110 962 611 8 061 562 2 497 732 45 287 438

397 562 255 028 92 613 1 488 881 677 459 485 641 132 933 2 218 775 790 049 731 120 270 185 3 169 516 761 533 747 709 332 910 3 097 610 585 571 487 033 110 323 2 291 128 317 791 321 222 111 256 1 131 286

2 042 798 1 392 734 256 228 6 076 212 82 460 71 600 29 148 383 026

1 716 299 990 432 314 326 7 896 3221 143 613 573 732 114 091 4 901 972

291 751 200 582 58 573 1 049 015 444 150 303 951 78 661 1 968 415

0 0 0 0 139 777 158 073 73 458 551 261 392 613 343 695 111 773 2 116 223 214 057 177 555 69 751 2 102 759 965 129 821 453 341 502 4 845 036 182 619 138 341 70 472 1 252 903

3 610 179 2 855 192 875 908 14 665 670 581 345 527 908 284 868 4 641 414

7 869 991 6 368 509 5 373 515 123 326 0413 755 078 773 354 213 337 54 717 875

9 192 1 121 459 7 504 180 67 827 39 534 8 750 9 048 016

138 739 77 612 24 162 3 256 547 92 243 23 584 4 202 2 819 248

2 442 335 4 349 937 4 657 063 12 542 908 244 184 333 248 151 282 1 008 749 30 550 14 735 3 735 960 696 9 648 1 935 882 2 028 629

22 543 12 112 3 409 3 113 450 63 853 18 221 3 564 3 654 082 29 483 18 229 2 613 5 089 869

369 705 134 959 29 340 2 838 916 599 41 2 5 532 738

1 289 1 243 395 2 924 670 592 723 568 642 270 319 6 285 470

16 929 004 7 989 225 1 728 941 65 661 9951 265 217 659 752 206 334 4 947 4832 924 840 1 845 278 489 674 12 137 6215 599 159 2 333 297 315 967 18 690 3394 591 236 1 821 510 305 113 20 513 3612 548 551 1 329 389 411 853 9 373 189

17 091 577 23 932 609 12 547 850 75 880 350 391 166 333 494 118 231 1 876 059

1 042 153 1 609 011 962 380 4 610 3977 751 146 8 943 913 4 142 633 29 242 8005 880 182 9 276 916 4 688 169 26 659 100

365 766 578 853 314 927 2 346 7591 661 166 3 190 423 2 321 509 11 145 2375 062 092 6 291 634 3 053 834 29 936 7023 989 481 5 204 436 2 435 899 16 692 335

351 561 229 726 89 126 8 101 647 721 051 857 472 528 809 5 142 720

1 692 890 1 786 301 789 511 11 464 013 187 388 218 086 98 248 1 234 345 589 432 520 872 118 828 3 068 934 17 440 17 233 6 589 106 636

898 629 1 030 110 565 846 7 054 0981 029 512 962 383 475 144 5 640 461

807 496 740 042 344 445 4 123 485 0 0 0 0

222 016 222 340 130 699 1 516 977

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284 491 256 564 179 036 2 721 9084 432 173 2 206 035 734 261 23 730 906

640 391 277 950 88 751 4 601 3233 093 949 1 402 338 326 377 13 783 604

46 116 27 557 7 536 349 282 101 863 40 338 11 373 1 478 421 549 853 457 852 300 224 3 518 275 20 726 11 874 6 321 7 605 228

41 37 7 42 846 117 17 58 144 373

58 5 17 16 233 0 0 0 64 151 0 0 3 70 843

26 9 28 11 202 127 61 26 16 372

3 217 267 85 1 803 041 8 001 5 799 3 248 3 643 342

185 300 99 497 367 8 955 5 379 2 751 1 295 458

1 530 862 415 603 67 978 6 029 072 269 698 124 851 40 738 3 111 744 15 073 7 059 2 389 233 162

1 237 882 277 163 21 008 2 598 576 8 209 6 531 3 844 85 591

4 485 551 2 605 184 1 033 507 66 500 0713 591 243 2 153 570 922 880 53 172 621

1 019 899 481 225 105 770 25 190 603 448 274 114 472 32 366 2 077 049 585 035 702 487 423 512 5 031 427 214 454 143 336 48 237 4 717 741 178 324 105 808 34 399 2 102 418

1 145 257 606 241 278 596 14 053 382 894 308 451 615 110 627 13 327 450 647 275 353 105 89 010 7 545 379

193 925 80 338 13 966 4 429 435 46 446 15 829 6 752 1 291 539 6 662 2 343 900 61 097

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GBD 2004: Projected DALYs by age, sex and cause for the year 2030, optimistic scenarioHigh income countries (a)

Male FemaleCode Cause Total 0-4 5-14 15-29 30-44 45-59 60-69 70-79 80+ Total 0-4 5-14 15-29 30-44 45-59 60-69U000 All Causes 117 355 401 1 540 405 1 729 045 9 788 040 9 092 707 12 462 115 10 398 648 8 658 071 5 637 098 59 306 129 1 328 721 1 676 248 8 474 008 7 714 802 9 954 769 9 121 052

U001 I.4 090 413 420 134 59 736 179 213 314 310 264 428 374 009 255 880 268 840 2 136 551 354 924 60 675 338 835 278 675 180 382 141 649

U002 A. Infectious and parasitic diseases 1 891 082 50 873 25 144 144 918 269 306 197 300 288 941 106 357 52 231 1 135 070 46 391 25 629 156 560 171 944 103 267 75 339

U003 1. Tuberculosis 56 439 659 579 2 940 5 167 6 832 5 250 6 985 5 301 33 713 552 618 2 835 2 769 2 751 2 646

U004 2. STDs excluding HIV 112 397 949 128 9 620 7 926 351 237 87 37 19 335 879 1 410 69 577 18 992 900 373

U005 a. Syphilis 3 060 548 5 384 386 72 186 81 35 1 696 511 6 368 328 32 22

U006 b. Chlamydia 83 654 31 54 4 314 3 312 119 22 0 0 7 852 29 1 253 60 825 13 026 553 115

U007 c. Gonorrhoea 24 109 370 69 4 921 4 218 149 24 0 0 9 750 333 152 8 276 5 493 87 16

U008 d. Other STDs 1 574 0 0 0 10 12 6 6 2 36 6 0 108 145 228 219

U009 3. HIV/AIDS 872 689 1 521 1 996 98 088 195 587 105 275 227 374 27 990 2 273 660 104 1 263 2 217 49 157 98 121 40 917 16 320

U010 4. Diarrhoeal diseases 224 089 28 774 8 476 17 724 18 601 14 520 8 041 8 044 6 578 110 759 27 695 7 957 14 306 14 597 14 344 9 792

U011 5. Childhood-cluster diseases 20 322 9 341 332 23 42 218 324 505 244 11 030 7 411 356 13 18 175 408

U012 a. Pertussis 16 803 9 150 167 0 0 5 0 0 0 9 323 7 297 179 0 0 0 0

U013 b. Poliomyelitis (c) 2 611 0 0 15 22 187 305 474 232 1 236 0 0 1 10 162 374

U014 c. Diphtheria 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0

U015 d. Measles 487 58 161 4 8 10 0 0 0 241 52 172 10 7 0 5

U016 e. Tetanus 420 132 3 5 12 15 19 30 12 229 62 4 2 2 13 29

U017 6. Meningitis 30 274 3 084 2 066 2 638 2 434 2 343 1 547 1 058 428 15 598 2 928 1 999 2 086 1 395 2 033 1 823

U018 7. Hepatitis B (d) 35 467 38 8 619 5 065 8 760 4 754 2 822 991 23 057 33 19 373 860 2 621 3 254

U019 Hepatitis C (d) 69 166 3 12 335 6 687 19 516 6 577 5 633 1 552 40 316 0 14 188 2 340 6 757 6 400

U020 8. Malaria 12 796 322 1 770 2 058 1 533 1 283 392 195 37 7 590 303 1 089 1 382 1 048 909 267

U021 9. Tropical-cluster diseases 3 533 115 509 363 560 502 244 72 12 2 378 77 301 149 227 230 106

U022 a. Trypanosomiasis 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

U023 b. Chagas disease 17 0 0 0 11 6 0 0 0 17 0 0 0 0 0 0

U024 c. Schistosomiasis 2 735 85 348 237 406 456 224 61 6 1 823 59 216 100 175 211 102

U025 d. Leishmaniasis 780 30 162 126 143 40 19 11 6 538 17 85 49 52 19 4

U026 e. lymphatic filariasis 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

U027 f. Onchocerciasis 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

U028 10. Leprosy 105 0 3 19 3 4 7 13 2 52 0 2 3 3 11 16

U029 11. Dengue 861 85 441 16 16 11 6 3 1 579 52 205 7 7 5 2

U030 12. Japanese encephalitis 764 85 150 64 54 16 10 9 2 389 131 135 39 32 22 9

U031 13. Trachoma 97 0 0 0 0 0 10 11 6 27 0 0 0 0 10 18

U032 14. Intestinal nematode infections 9 152 332 1 611 791 925 660 297 162 48 4 826 304 1 454 522 646 672 362

U033 a. Ascariasis 1 695 195 695 0 0 0 0 0 0 889 178 627 0 0 0 0

U034 b. Trichuriasis 1 745 137 778 0 0 0 0 0 0 917 126 701 0 0 0 0

U035 c. Hookworm disease 5 520 0 139 726 925 653 266 137 46 2 891 0 125 509 637 660 354

U036 Other intestinal infections 193 0 0 65 0 6 31 25 2 129 0 0 13 9 11 7

U037 Other infectious diseases 443 050 5 562 7 064 9 635 24 723 37 009 33 877 52 770 34 720 205 360 4 814 7 855 15 930 30 896 30 914 33 544

U038 B. Respiratory infections 1 032 179 12 916 22 126 16 359 28 831 51 701 65 725 131 130 201 348 530 134 12 929 21 517 10 012 15 860 31 999 41 386

U039 1. Lower respiratory infections 944 504 8 664 3 699 11 939 24 088 47 851 62 992 128 498 198 609 486 341 9 006 3 942 5 245 11 089 28 453 38 655

U040 2. Upper respiratory infections 47 841 609 1 938 4 383 4 618 3 813 2 669 2 601 2 705 23 336 507 1 935 4 768 4 727 3 426 2 652

U041 3. Otitis media 39 834 3 642 16 489 37 125 37 63 30 33 20 457 3 415 15 640 0 43 120 79

U042 C. Maternal conditions 185 807 0 0 0 0 0 0 0 0 0 0 1 876 131 542 51 835 554 0

U043 1. Maternal haemorrhage 1 368 0 0 0 0 0 0 0 0 0 0 0 744 613 11 0

U044 2. Maternal sepsis 40 718 0 0 0 0 0 0 0 0 0 0 0 32 888 7 819 11 0

U045 3. Hypertensive disorders 1 392 0 0 0 0 0 0 0 0 0 0 0 695 681 16 0

U046 4. Obstructed labour 7 169 0 0 0 0 0 0 0 0 0 0 0 4 915 2 242 12 0

U047 5. Abortion 7 380 0 0 0 0 0 0 0 0 0 0 1 824 5 022 528 6 0

U048 Other maternal conditions 127 780 0 0 0 0 0 0 0 0 0 0 52 87 278 39 952 498 0

U049 D. Perinatal conditions (e) 609 472 333 214 820 264 157 41 45 16 0 334 555 274 124 370 252 93 44 26

U050 1. Prematurity and low birth weight 258 397 142 417 169 52 8 0 7 0 0 142 652 115 642 77 24 0 0 0

U051 2. Birth asphyxia and birth trauma 165 428 87 406 401 120 85 14 30 16 0 88 072 77 059 145 95 34 7 15

U052 3. 185 647 103 391 250 91 64 27 8 0 0 103 831 81 422 147 133 59 37 11

U053 E. Nutritional deficiencies 371 872 23 132 11 646 17 672 16 017 15 386 19 298 18 379 15 261 136 791 21 481 11 283 40 469 38 943 44 518 24 897

U054 1. Protein-energy malnutrition 54 143 17 572 46 249 525 1 379 1 135 2 126 3 074 26 106 16 281 46 87 317 871 1 090

U055 2. Iodine deficiency 947 311 109 14 0 5 27 7 19 493 302 118 10 0 14 3

U056 3. Vitamin A deficiency 37 4 4 0 0 0 0 0 21 30 4 4 0 0 0 0

U057 4. Iron-deficiency anaemia 309 869 5 185 11 263 17 258 15 172 13 486 17 760 15 835 11 535 107 494 4 808 11 020 39 765 37 947 43 143 23 466U058 Other nutritional disorders 6 877 60 223 151 320 517 376 411 611 2 669 86 95 606 678 490 337

Communicable, maternal, perinatal and nutritional conditions

Neonatal infections and other conditions (f)

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U059 II. Noncommunicable diseases 103 846 187 981 879 1 427 031 7 250 615 7 065 563 11 144 022 9 639 880 8 136 468 5 186 292 50 831 751 885 450 1 419 779 7 247 767 6 779 492 9 308 042 8 708 579

U060 A. Malignant neoplasms 17 030 062 15 476 41 252 155 542 501 786 2 464 822 2 787 285 2 271 978 1 030 211 9 268 352 13 573 33 153 127 671 666 232 1 936 628 2 103 247

U061 1. Mouth and oropharynx cancers 390 516 65 248 3 565 20 339 128 163 87 849 43 429 14 266 297 923 78 162 1 416 7 677 27 243 25 202

U062 2. Oesophagus cancer 472 800 3 13 969 15 084 123 116 127 493 81 776 27 834 376 288 0 0 314 3 093 21 655 29 330

U063 3. Stomach cancer 983 498 0 16 3 875 37 047 157 087 181 788 157 849 82 891 620 553 0 1 3 720 28 458 74 677 83 198

U064 4. Colon and rectum cancers 2 077 538 9 58 7 748 58 538 295 894 336 208 289 329 143 633 1 131 418 39 129 6 174 51 005 203 041 248 155

U065 5. Liver cancer 818 931 689 524 3 285 31 069 200 338 178 578 125 379 40 164 580 027 512 444 1 836 8 016 43 973 69 186

U066 6. Pancreas cancer 844 307 16 2 1 054 21 279 135 383 149 442 115 430 46 303 468 909 24 32 1 013 11 582 68 106 111 632

U067 7. Trachea, bronchus, lung cancers 3 288 906 1 1 4 83 474 640 844 729 526 519 835 135 221 2 108 906 4 38 2 55 593 285 279 387 286

U068 8. Melanoma and other skin cancers 299 577 34 72 5 568 24 662 55 426 46 392 37 591 19 329 189 074 19 148 4 100 16 978 28 748 23 898

U069 9. Breast cancer 1 658 348 0 15 145 758 2 966 3 133 2 786 1 305 11 109 2 38 10 745 234 717 558 505 419 681

U070 10. Cervix uteri cancer 181 767 0 0 0 0 0 0 0 0 0 2 9 9 122 42 999 60 019 36 997

U071 11. Corpus uteri cancer 394 634 0 0 0 0 0 0 0 0 0 0 53 2 596 27 710 130 305 121 384

U072 12. Ovary cancer 386 352 0 0 0 0 0 0 0 0 0 52 367 7 538 35 188 113 312 112 267

U073 13. Prostate cancer 843 611 64 71 261 2 700 77 274 225 770 306 039 231 432 843 611 0 0 0 0 0 0

U074 14. Bladder cancer 490 181 37 181 1 588 8 782 71 983 101 501 111 739 72 896 368 708 8 5 459 3 839 15 124 27 736

U075 15. Lymphomas, multiple myeloma 899 035 526 2 918 24 633 41 972 119 533 138 152 121 361 54 651 503 748 526 1 932 13 497 22 867 69 726 107 930

U076 16. Leukaemia 641 828 4 651 13 464 38 687 35 419 68 349 89 676 82 081 40 876 373 204 4 376 10 092 23 332 28 318 43 339 57 649

U077 Other malignant neoplasms 2 358 233 9 381 23 667 64 159 120 664 388 465 391 776 277 353 119 410 1 394 875 7 930 19 702 41 806 88 189 193 576 241 716

U078 B. Other neoplasms 361 071 2 564 3 101 7 565 15 423 34 703 42 308 50 151 38 539 194 354 2 751 3 346 5 528 11 547 23 955 31 731

U079 C. Diabetes mellitus 4 249 465 795 3 345 44 092 257 771 618 112 482 159 355 226 174 922 1 936 422 561 2 671 28 459 340 153 622 998 511 921

U080 D. Endocrine disorders 1 529 921 68 056 37 344 85 104 121 791 156 472 96 133 92 372 61 979 719 252 58 539 27 553 99 942 109 973 189 248 89 528

U081 E. Neuropsychiatric conditions 33 705 978 195 600 805 953 5 721 280 3 216 679 1 788 622 1 141 552 1 149 225 1 083 964 15 102 875 181 127 740 774 5 942 136 3 342 319 2 296 172 1 521 556

U082 1. Unipolar depressive disorders 10 360 138 0 261 618 1 169 948 1 105 538 681 300 272 764 59 722 22 786 3 573 675 0 275 017 2 242 564 2 085 190 1 420 888 529 124

U083 2. Bipolar disorder 1 421 118 0 29 307 600 976 80 988 3 265 1 194 293 83 716 105 0 23 316 588 069 86 733 4 210 1 964

U084 3. Schizophrenia 1 454 508 0 153 075 541 622 49 681 9 667 3 162 1 969 864 760 039 0 75 070 549 984 45 013 14 575 4 602

U085 4. Epilepsy 476 035 10 040 37 701 72 833 59 982 40 554 19 709 10 675 5 290 256 785 8 634 33 542 57 843 45 487 32 881 19 090

U086 5. Alcohol use disorders 4 041 391 0 37 007 1 529 932 1 053 876 456 581 92 367 21 040 4 060 3 194 862 0 11 429 454 231 233 322 115 181 24 597

U087 6. Alzheimer and other dementias 6 808 593 24 372 12 729 17 735 14 121 82 465 444 872 773 074 894 715 2 264 083 23 391 12 236 17 460 14 431 105 141 610 487

U088 7. Parkinson disease 808 283 0 0 391 7 947 56 784 117 416 149 967 87 567 420 072 52 0 38 5 494 46 537 99 676

U089 8. Multiple sclerosis 291 824 29 9 331 41 162 38 586 25 528 8 748 3 620 714 127 718 0 9 324 45 046 49 343 34 465 15 721

U090 9. Drug use disorders 1 845 736 0 15 816 876 624 394 391 94 786 5 694 179 33 1 387 523 0 10 042 277 785 131 531 35 587 2 993

U091 10. Post-traumatic stress disorder 494 969 0 2 593 58 865 44 127 20 797 1 226 664 280 128 551 0 2 928 164 364 108 763 82 360 3 453

U092 11. Obsessive-compulsive disorder 575 896 0 7 672 138 078 73 476 11 910 3 241 1 303 481 236 162 0 9 413 187 492 114 666 23 374 3 705

U093 12. Panic disorder 757 224 0 11 588 220 159 3 342 14 903 2 039 1 376 271 253 679 0 9 839 444 961 5 156 33 477 5 109

U094 13. Insomnia (primary) 805 251 0 4 732 83 036 91 925 81 383 49 610 21 234 5 968 337 888 0 4 177 91 109 120 810 118 214 79 694

U095 14. Migraine 1 336 666 10 497 135 778 177 914 16 276 229 60 14 1 340 768 14 215 201 222 667 987 112 305 130 35

U096 15. Mental retardation, lead-caused 138 840 63 888 727 1 663 1 650 1 695 986 671 144 71 423 61 615 344 1 094 1 151 1 470 833

Other neuropsychiatric disorders 2 089 506 86 773 86 279 190 343 180 773 206 775 118 463 103 426 60 710 1 033 542 73 220 62 877 152 111 182 924 227 681 120 472

U098 F. Sense organ diseases 10 726 763 9 430 116 291 243 634 817 272 1 412 990 1 396 901 779 920 205 563 4 982 000 9 995 114 329 237 694 796 326 1 481 179 1 700 080

U099 1. Glaucoma 489 965 45 270 2 389 15 750 70 781 64 507 27 709 10 937 192 388 393 1 379 4 706 24 615 88 875 103 339

U100 2. Cataracts 446 579 145 1 544 9 487 31 147 79 121 52 750 21 252 5 313 200 757 300 2 221 9 311 26 435 80 367 70 389

U101 3. Refractive errors 2 894 798 9 086 114 233 201 087 253 886 232 249 301 649 178 468 58 577 1 349 235 8 587 108 571 184 935 246 083 236 725 369 426

U102 4. Hearing loss, adult onset 5 004 539 0 0 24 279 458 644 763 798 723 807 444 152 87 307 2 501 985 0 0 23 411 380 191 687 899 821 200

U103 5. Macular degeneration and other (g) 1 890 883 155 244 6 393 57 846 267 042 254 189 108 339 43 429 737 636 716 2 158 15 331 119 002 387 312 335 727

U104 G. Cardiovascular diseases 16 373 296 30 689 12 754 215 565 780 894 2 026 389 1 965 088 2 021 972 1 713 645 8 766 996 25 487 10 557 103 994 344 639 722 798 942 163

U105 1. Rheumatic heart disease 101 472 239 262 1 335 2 899 8 546 10 128 8 235 5 771 37 416 155 233 1 284 2 516 5 906 12 779

U106 2. Hypertensive heart disease 848 389 228 84 4 708 25 490 92 148 101 543 85 442 92 082 401 725 127 112 1 831 8 161 23 836 43 214

U107 3. Ischaemic heart disease 7 306 706 532 439 41 717 349 660 1 113 967 1 061 431 1 041 934 706 428 4 316 109 577 371 7 701 82 703 270 233 468 216

U108 4. Cerebrovascular disease 4 289 789 5 465 2 435 48 457 180 612 450 292 424 473 472 164 432 733 2 016 631 4 109 2 271 33 464 157 732 280 167 250 868

U109 5. Inflammatory heart diseases (h) 566 001 8 745 2 998 30 198 57 695 77 131 74 648 66 116 39 185 356 716 7 510 2 432 10 630 18 200 26 341 29 192U110 Other cardiovascular diseases 3 260 939 15 479 6 535 89 150 164 538 284 305 292 864 348 081 437 446 1 638 399 13 010 5 139 49 084 75 326 116 315 137 894

U111 H. Respiratory diseases 5 895 297 136 056 274 938 488 496 323 324 654 065 486 731 529 201 372 669 3 265 480 114 900 331 452 381 074 314 469 360 913 335 762

U112 1. Chronic obstructive pulmonary disea 2 532 735 1 007 2 336 39 995 151 103 430 754 304 006 312 570 195 097 1 436 869 938 389 28 392 228 694 225 784 199 294

U113 2. Asthma 1 863 330 109 317 253 311 398 667 99 196 65 773 22 621 17 763 13 500 980 150 91 661 320 575 293 493 31 496 45 324 42 288

U114 Other respiratory diseases 1 499 231 25 732 19 291 49 834 73 024 157 538 160 104 198 868 164 071 848 462 22 302 10 488 59 189 54 279 89 805 94 180

U115 I. Digestive diseases 4 235 491 18 412 9 654 63 439 448 767 868 819 430 871 304 372 181 462 2 325 796 16 912 8 742 51 488 292 801 434 925 303 156

U116 1. Peptic ulcer disease 191 127 167 222 6 855 12 168 26 932 19 225 19 832 15 985 101 387 81 161 2 033 7 438 19 491 10 947

U117 2. Cirrhosis of the liver 1 430 961 635 729 6 911 208 261 459 847 203 836 88 654 21 947 990 820 163 144 3 239 77 657 140 079 95 646

U118 3. Appendicitis 24 319 96 1 005 2 732 4 086 2 409 1 451 1 666 994 14 439 38 759 1 379 2 408 1 391 1 006

U119 Other digestive diseases 2 589 085 17 514 7 698 46 941 224 251 379 631 206 359 194 220 142 536 1 219 149 16 630 7 678 44 837 205 298 273 963 195 555

U120 J. Genitourinary diseases 1 432 981 5 254 2 587 14 892 31 552 268 543 198 884 193 955 173 024 888 693 5 232 4 572 13 375 25 739 61 086 86 298

U121 1. Nephritis and nephrosis 722 154 3 767 1 333 9 288 21 345 52 619 78 101 106 262 102 834 375 550 3 420 2 473 5 369 12 890 36 893 59 223

U122 2. Benign prostatic hypertrophy 378 377 0 0 0 0 196 735 98 551 52 640 30 451 378 377 0 0 0 0 0 0

U123 Other genitourinary system diseases 332 450 1 487 1 254 5 605 10 207 19 190 22 232 35 052 39 739 134 766 1 811 2 099 8 006 12 849 24 193 27 075

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U124 K. Skin diseases 296 318 1 317 2 776 7 710 13 441 19 889 19 625 25 559 27 817 118 134 1 556 2 768 8 821 15 571 23 209 26 018

U125 L. Musculoskeletal diseases 6 013 672 6 154 25 942 99 514 461 840 708 797 503 404 339 185 114 489 2 259 325 6 270 53 502 161 060 450 541 1 029 180 944 114

U126 1. Rheumatoid arthritis 1 045 378 929 8 191 15 750 46 502 101 122 65 902 38 530 13 985 290 912 3 480 30 828 49 604 126 434 282 779 142 183

U127 2. Osteoarthritis 3 387 760 0 138 23 547 181 495 396 315 347 113 242 247 55 844 1 246 699 0 218 19 866 174 251 542 388 667 076

U128 3. Gout 420 379 0 0 13 176 163 460 125 663 36 648 13 687 7 559 360 193 0 0 4 249 12 196 17 126 12 836

U129 4. Low back pain 283 021 3 956 13 228 25 562 44 299 37 444 15 063 7 673 3 549 150 774 1 812 16 389 17 881 33 324 33 837 15 245

U130 Other musculoskeletal disorders 877 134 1 268 4 385 21 478 26 083 48 252 38 680 37 048 33 553 210 746 977 6 067 69 459 104 335 153 050 106 773

U131 M. Congenital anomalies 1 062 802 471 261 12 120 31 037 18 752 16 355 7 266 3 828 1 860 562 479 428 635 10 956 16 401 13 402 15 344 8 035

U132 1. Abdominal wall defect 4 019 2 153 23 34 42 11 0 0 0 2 264 1 754 0 0 0 0 0

U133 2. Anencephaly 12 730 5 695 40 38 21 0 0 0 0 5 794 6 876 34 26 0 0 0

U134 3. Anorectal atresia 484 284 0 0 0 0 0 0 0 284 197 0 0 0 0 0

U135 4. Cleft lip 6 003 3 016 0 0 0 0 0 0 0 3 016 2 987 0 0 0 0 0

U136 5. Cleft palate 8 068 3 874 0 0 0 10 19 11 7 3 921 4 125 0 0 19 0 0

U137 6. Oesophageal atresia 1 387 808 43 0 15 0 0 5 4 875 480 0 0 0 11 9

U138 7. Renal agenesis 10 425 6 434 0 63 77 32 31 21 29 6 686 3 482 45 35 52 15 33

U139 8. Down syndrome 228 240 108 180 400 2 063 2 963 6 619 2 556 287 14 123 082 92 068 288 1 260 1 878 6 621 2 791

U140 9. Congenital heart anomalies 494 272 219 787 5 543 16 869 9 448 5 541 2 238 1 832 825 262 083 202 055 4 477 7 771 6 371 5 015 2 677

U141 10. Spina bifida 41 954 17 429 167 1 245 760 143 31 24 4 19 801 19 735 276 748 1 033 240 91

U142 Other Congenital anomalies 255 219 103 600 5 903 10 725 5 426 4 000 2 391 1 648 978 134 672 94 875 5 835 6 561 4 049 3 442 2 433

U143 N. Oral conditions 933 071 20 815 78 972 72 744 56 272 105 444 81 673 19 524 6 147 441 592 19 913 75 403 70 124 55 781 110 407 104 970

U144 1. Dental caries 531 571 20 276 78 954 62 835 30 353 34 373 22 154 10 432 4 969 264 347 19 293 75 226 60 468 30 003 33 232 25 083

U145 2. Periodontal disease 36 497 0 0 4 588 10 441 1 686 766 389 198 18 067 0 0 4 413 10 372 1 786 916

U146 3. Edentulism 356 087 0 0 4 926 14 864 68 690 58 324 8 251 529 155 584 0 0 4 819 14 892 74 628 78 144

U147 Other oral diseases 8 915 538 18 395 615 694 430 453 451 3 594 620 177 424 516 762 828

U148 III.Injuries 9 418 801 138 392 242 277 2 358 213 1 712 833 1 053 665 384 758 265 722 181 965 6 337 826 88 347 195 794 887 405 656 635 466 345 270 824

U149 A. Unintentional injuries 5 588 727 116 401 175 894 1 263 390 750 842 502 881 225 066 200 239 156 435 3 391 148 71 251 152 088 643 444 385 034 283 862 201 109

U150 1. Road traffic accidents 2 378 780 34 556 64 558 835 570 329 156 168 902 59 156 33 599 12 411 1 537 908 18 732 57 116 413 970 167 052 98 160 45 772

U151 2. Poisonings 438 681 1 898 1 240 82 937 116 501 49 842 6 454 3 681 1 477 264 031 594 1 753 37 943 74 849 42 709 10 248

U152 3. Falls 1 111 865 23 319 33 466 116 959 108 681 105 801 67 301 78 270 76 333 610 130 16 572 27 829 57 316 45 939 47 366 62 355

U153 4. Fires 124 678 5 585 6 208 12 555 16 224 14 553 6 552 5 204 2 810 69 691 3 775 7 170 10 762 9 224 9 011 6 116

U154 5. Drownings 174 464 10 690 8 918 39 173 24 687 19 445 9 825 8 410 3 843 124 992 5 242 4 887 6 917 5 739 7 175 6 990

U155 6. Other unintentional injuries 1 360 259 40 352 61 505 176 196 155 594 144 338 75 777 71 075 59 560 784 397 26 336 53 332 116 535 82 232 79 442 69 629

U156 B. Intentional injuries 3 830 074 21 991 66 383 1 094 823 961 991 550 783 159 692 65 484 25 530 2 946 678 17 096 43 707 243 962 271 601 182 483 69 715

U157 1. Self-inflicted injuries 2 891 179 0 44 575 660 311 772 124 495 987 148 947 62 083 24 489 2 208 516 0 30 642 164 952 214 788 158 766 63 209

U158 2. Violence 862 205 21 989 21 493 389 642 166 628 51 239 10 291 3 247 984 665 515 17 093 12 859 76 650 56 150 23 110 6 402

U159 3. War and civil conflict 50 621 0 305 31 966 14 069 1 935 275 42 17 48 610 0 205 906 480 301 87

U160 Other intentional injuries 26 070 2 10 12 903 9 170 1 622 180 111 40 24 037 4 0 1 454 183 306 18

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Female70-79 80+ Total

10 589 891 9 189 782 58 049 272

250 125 348 597 1 953 861

106 102 70 780 756 012 5 955 4 600 22 726

500 431 93 063 69 28 1 364 0 0 75 802 0 2 14 359

431 402 1 538 4 466 124 212 585

13 173 11 467 113 330 635 276 9 293

4 0 7 480 586 242 1 375

0 0 1 0 0 247

45 35 190 1 768 642 14 676 3 932 1 318 12 410 9 840 3 311 28 850

168 40 5 206 52 13 1 155 0 0 0 0 0 0

40 9 912 12 3 243 0 0 0 0 0 0 3 13 53 2 1 282 6 1 375

25 17 70 271 95 4 326

0 0 806 0 0 828

253 90 2 629 18 5 64

65 307 48 429 237 689 117 604 250 738 502 045 114 733 247 039 458 163

2 830 3 660 24 505 41 39 19 377 0 0 185 807 0 0 1 368 0 0 40 718 0 0 1 392 0 0 7 169 0 0 7 380 0 0 127 780 5 3 274 917

0 2 115 745

0 0 77 356

5 1 81 816 26 414 27 076 235 081 3 066 6 277 28 036

2 3 454 0 0 8

22 695 19 531 202 375 650 1 265 4 208

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10 074 608 8 590 718 53 014 4352 002 590 878 616 7 761 709

20 138 10 676 92 593 28 219 13 900 96 511

101 585 71 306 362 945 274 381 163 195 946 120 81 381 33 556 238 904

125 830 57 180 375 398 361 849 89 949 1 180 001 22 820 13 790 110 502

303 499 120 053 1 647 240 23 951 8 668 181 767 84 230 28 356 394 634 89 200 28 428 386 352

0 0 0 43 434 30 868 121 473

126 094 52 714 395 286 67 611 33 906 268 624

248 367 122 071 963 358 47 889 39 970 166 717

525 398 280 883 2 313 043 128 795 107 091 810 669

1 948 775 2 630 244 18 603 103 161 373 72 309 6 786 463

452 268 705 013 3 350 1 876 694 469

13 901 7 871 219 250 6 380 1 389 846 529

1 425 553 2 335 810 4 544 509 145 326 91 087 388 211

8 537 1 671 164 107 207 67 458 213

3 256 1 293 366 419 749 335 339 734

4 051 954 503 545 44 769 8 590 467 363

5 1 995 898 681 229 67 416

130 185 106 495 1 055 9641 062 707 342 452 5 744 763

51 999 22 272 297 577 44 290 12 508 245 821

286 178 105 059 1 545 563 482 776 107 077 2 502 554 197 465 95 535 1 153 247

2 463 177 2 993 484 7 606 300 23 977 17 207 64 056

144 168 225 214 446 6641 085 748 1 075 048 2 990 598

685 011 859 534 2 273 157 64 436 50 545 209 285

459 837 765 936 1 622 540 430 214 361 033 2 629 817 240 487 171 889 1 095 867 33 096 25 248 883 180

156 632 163 896 650 770 447 839 353 833 1 909 695 23 643 25 945 89 740 94 864 28 348 440 140 1 669 1 229 9 880

327 663 298 311 1 369 936 168 615 179 370 544 288 112 978 113 357 346 604

0 0 0 55 638 66 013 197 683

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39 911 60 329 178 184 762 045 347 635 3 754 347 80 672 38 486 754 466

553 319 183 942 2 141 061 10 466 3 313 60 186 9 099 4 658 132 246

108 490 117 236 666 387 5 063 2 486 500 323

0 0 1 754 0 0 6 937 0 3 200 0 0 2 987 0 3 4 147 0 13 513

55 22 3 739 228 23 105 158

2 537 1 287 232 190 21 8 22 153

2 222 1 129 120 546 41 589 13 290 491 479 15 206 8 713 267 224

590 354 18 431 24 890 3 132 200 504

904 1 091 5 321

265 157 250 467 3 080 975 224 421 236 370 2 197 578

31 186 8 884 840 872 4 590 1 964 174 650

107 428 136 930 501 735 5 776 3 154 54 987 7 768 4 755 49 472

67 674 80 684 575 862 40 737 14 096 883 397 37 281 13 025 682 663

3 376 1 051 196 690 24 9 2 011 56 12 2 032

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GBD 2004: Projected DALYs by age, sex and cause for the year 2030, optimistic scenarioUpper middle income countries (a)

Male FemaleCode Cause Total 0-4 5-14 15-29 30-44 45-59 60-69 70-79 80+ Total 0-4 5-14 15-29 30-44 45-59 60-69U000 All Causes 90 503 579 2 489 758 1 838 036 9 803 009 10 041 344 11 184 120 5 884 327 4 009 642 2 166 149 47 416 386 2 063 883 1 737 433 6 301 468 7 770 094 8 843 674 6 277 767

U001 I.8 763 545 1 072 977 238 642 594 658 1 306 021 697 082 205 017 125 446 76 811 4 316 654 854 432 243 958 833 202 1 485 141 549 074 172 944

U002 A. Infectious and parasitic diseases 5 952 194 198 452 171 562 543 861 1 223 214 594 176 142 036 49 809 19 118 2 942 228 173 793 174 010 582 988 1 352 867 478 869 119 184

U003 1. Tuberculosis 615 710 7 122 5 767 79 691 211 007 120 525 19 629 7 778 2 933 454 452 8 116 7 296 43 153 56 534 30 694 8 768

U004 2. STDs excluding HIV 267 072 13 134 614 37 972 20 468 915 477 804 469 74 854 10 958 2 626 131 015 43 975 1 537 679

U005 a. Syphilis 26 897 5 125 66 4 817 3 654 194 131 315 152 14 453 3 488 77 4 876 3 578 62 91

U006 b. Chlamydia 126 000 36 152 8 051 3 017 97 13 0 0 11 365 33 1 902 92 129 19 599 814 157

U007 c. Gonorrhoea 110 308 7 960 395 25 061 13 577 313 42 0 0 47 348 7 433 643 33 889 20 609 291 83

U008 d. Other STDs 3 866 14 1 43 221 311 292 490 317 1 687 4 5 121 189 370 347

U009 3. HIV/AIDS 4 131 523 66 826 90 005 349 542 908 012 416 405 87 608 5 689 19 1 924 106 68 137 95 883 330 704 1 195 548 398 751 73 636

U010 4. Diarrhoeal diseases 344 707 67 843 27 757 22 064 24 651 13 881 8 726 9 475 4 897 179 295 53 594 25 660 24 242 16 244 12 755 10 737

U011 5. Childhood-cluster diseases 20 714 10 249 697 212 229 158 78 90 25 11 738 7 800 645 61 72 129 63

U012 a. Pertussis 14 149 7 313 424 3 0 0 5 0 0 7 744 5 938 425 37 5 0 0

U013 b. Poliomyelitis (c) 203 1 7 13 45 21 20 11 10 127 2 0 0 22 27 9

U014 c. Diphtheria 338 120 33 0 5 14 1 0 7 181 80 18 3 3 28 9

U015 d. Measles 4 417 2 322 177 120 3 9 0 0 0 2 631 1 582 188 14 1 0 0

U016 e. Tetanus 1 606 494 56 76 177 114 51 79 8 1 055 198 15 8 40 73 44

U017 6. Meningitis 53 273 6 283 3 340 5 915 5 881 3 455 1 860 1 462 440 28 636 4 552 3 565 5 914 2 203 2 907 2 291

U018 7. Hepatitis B (d) 21 312 348 278 1 918 2 975 4 098 2 140 1 526 401 13 684 243 178 1 123 839 1 937 1 549

U019 Hepatitis C (d) 12 909 25 60 619 1 488 2 454 1 085 731 129 6 591 22 20 384 415 2 133 1 730

U020 8. Malaria 111 607 11 397 16 366 14 230 8 186 4 751 1 275 594 160 56 960 8 452 15 341 13 976 10 031 4 486 1 340

U021 9. Tropical-cluster diseases 69 182 1 022 5 132 15 345 9 312 6 723 3 306 1 618 619 43 078 705 3 247 10 265 3 757 4 456 1 617

U022 a. Trypanosomiasis 728 13 132 134 138 97 8 5 0 527 11 52 48 43 35 10

U023 b. Chagas disease 38 887 7 5 11 450 4 525 3 336 2 047 1 030 540 22 939 3 8 8 877 1 845 2 725 866

U024 c. Schistosomiasis 23 946 888 4 449 2 079 3 446 2 593 1 172 549 71 15 247 605 3 041 1 000 1 640 1 320 700

U025 d. Leishmaniasis 1 648 38 131 405 358 239 38 18 5 1 230 22 47 111 88 128 11

U026 e. lymphatic filariasis 3 397 62 373 1 159 742 399 24 10 2 2 771 49 67 168 99 211 18

U027 f. Onchocerciasis 576 14 43 118 104 60 16 7 2 364 14 33 60 42 37 13

U028 10. Leprosy 3 477 18 263 230 318 478 772 400 17 2 496 18 259 240 239 145 23

U029 11. Dengue 1 178 40 408 51 64 47 19 28 2 658 35 326 39 64 24 17

U030 12. Japanese encephalitis 2 051 185 571 133 111 35 22 33 6 1 096 149 497 114 86 51 31

U031 13. Trachoma 4 466 1 3 34 430 501 245 201 37 1 452 2 4 43 612 875 659

U032 14. Intestinal nematode infections 40 925 2 333 12 002 2 734 2 327 1 414 476 287 108 21 680 2 159 11 060 2 105 1 684 1 271 512

U033 a. Ascariasis 9 898 1 115 4 045 12 10 0 0 8 13 5 203 1 031 3 644 15 2 1 3

U034 b. Trichuriasis 12 155 1 215 5 073 1 1 1 0 0 0 6 291 1 125 4 737 1 1 1 0

U035 c. Hookworm disease 18 797 0 2 879 2 720 2 310 1 413 450 279 94 10 146 0 2 679 2 089 1 681 1 254 497

U036 Other intestinal infections 75 3 4 1 6 0 25 0 1 40 3 1 0 0 16 12

U037 Other infectious diseases 253 037 11 638 8 669 13 205 27 803 18 347 14 332 19 118 8 856 121 969 8 852 7 711 19 648 20 608 16 737 15 551

U038 B. Respiratory infections 818 601 80 212 27 325 28 464 67 667 90 167 52 563 65 169 50 881 462 449 57 732 25 139 25 695 23 378 38 275 37 615

U039 1. Lower respiratory infections 751 061 73 956 14 449 24 339 62 607 86 939 50 969 64 271 50 392 427 922 52 724 13 238 20 469 19 214 35 130 35 944

U040 2. Upper respiratory infections 39 599 3 498 2 212 3 768 4 732 2 963 1 339 848 471 19 832 2 517 2 156 4 671 3 975 3 001 1 603

U041 3. Otitis media 27 941 2 758 10 664 357 329 264 255 50 19 14 695 2 492 9 745 555 188 143 68

U042 C. Maternal conditions 259 146 0 0 0 0 0 0 0 0 0 0 6 264 176 491 74 603 1 788 0

U043 1. Maternal haemorrhage 9 229 0 0 0 0 0 0 0 0 0 0 0 3 865 5 226 138 0

U044 2. Maternal sepsis 36 922 0 0 0 0 0 0 0 0 0 0 107 29 202 7 464 149 0

U045 3. Hypertensive disorders 13 558 0 0 0 0 0 0 0 0 0 0 175 7 538 5 627 219 0

U046 4. Obstructed labour 30 726 0 0 0 0 0 0 0 0 0 0 0 21 326 9 231 169 0

U047 5. Abortion 51 855 0 0 0 0 0 0 0 0 0 0 5 696 41 159 4 991 10 0

U048 Other maternal conditions 116 855 0 0 0 0 0 0 0 0 0 0 286 73 401 42 064 1 104 0

U049 D. Perinatal conditions (e) 1 131 901 645 010 0 3 0 0 1 0 0 645 013 486 887 0 0 0 1 0

U050 1. Prematurity and low birth weight 456 101 262 236 0 3 0 0 0 0 0 262 239 193 862 0 0 0 0 0

U051 2. Birth asphyxia and birth trauma 357 713 198 656 0 0 0 0 0 0 0 198 656 159 057 0 0 0 0 0

U052 3. 318 087 184 118 0 0 0 0 0 0 0 184 118 133 969 0 0 0 0 0

U053 E. Nutritional deficiencies 601 702 149 303 39 755 22 329 15 140 12 739 10 417 10 468 6 812 266 963 136 019 38 546 48 029 34 293 30 141 16 145

U054 1. Protein-energy malnutrition 150 619 71 082 975 1 122 2 573 1 108 788 1 243 1 230 80 122 62 937 1 121 1 143 642 518 547

U055 2. Iodine deficiency 166 371 64 863 19 905 8 0 9 2 4 0 84 791 61 592 19 853 22 36 60 4

U056 3. Vitamin A deficiency 1 739 860 107 3 7 36 8 5 0 1 025 603 100 0 1 2 0

U057 4. Iron-deficiency anaemia 268 463 11 703 18 022 20 592 11 657 10 946 9 248 8 538 5 130 95 836 10 195 16 696 45 305 31 815 28 234 14 934U058 Other nutritional disorders 14 510 796 745 604 902 640 371 678 452 5 188 692 776 1 559 1 799 1 328 660

Communicable, maternal, perinatal and nutritional conditions

Neonatal infections and other conditions (f)

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U059 II. Noncommunicable diseases 69 527 367 1 235 177 1 200 800 4 894 344 6 137 608 9 317 559 5 415 567 3 731 081 2 017 554 33 949 691 1 077 653 1 225 653 4 521 049 5 552 656 7 802 693 5 852 451

U060 A. Malignant neoplasms 9 137 816 22 290 50 454 169 179 450 945 1 606 325 1 187 744 825 965 338 430 4 651 333 18 486 41 179 119 279 520 371 1 403 411 1 089 767

U061 1. Mouth and oropharynx cancers 294 525 168 580 5 364 24 655 118 034 51 792 23 253 7 047 230 892 155 227 1 326 6 327 20 030 15 914

U062 2. Oesophagus cancer 262 121 53 26 1 097 14 697 82 288 48 635 25 965 8 765 181 527 10 76 1 117 10 606 22 667 20 179

U063 3. Stomach cancer 838 390 94 340 7 462 49 788 174 190 120 386 91 208 39 104 482 571 47 215 5 453 33 588 85 876 90 455

U064 4. Colon and rectum cancers 905 871 75 469 9 446 40 987 130 272 106 645 95 136 45 184 428 213 24 224 5 095 33 418 113 909 124 605

U065 5. Liver cancer 304 453 957 607 3 278 17 762 57 828 45 763 32 063 9 910 168 168 835 519 2 222 9 545 36 668 38 654

U066 6. Pancreas cancer 337 343 29 174 1 670 17 115 66 457 44 575 30 631 11 943 172 596 8 45 952 7 558 37 891 46 705

U067 7. Trachea, bronchus, lung cancers 1 714 529 0 1 2 90 003 492 473 386 293 197 364 55 913 1 222 050 0 1 1 39 687 172 318 146 405

U068 8. Melanoma and other skin cancers 136 268 94 97 3 872 12 906 26 139 12 618 9 248 5 900 70 875 65 106 2 457 10 201 19 618 12 771

U069 9. Breast cancer 853 926 6 0 36 583 2 040 1 182 765 596 5 208 49 282 5 973 128 793 340 115 190 407

U070 10. Cervix uteri cancer 373 831 0 0 0 0 0 0 0 0 0 24 426 18 433 72 818 145 752 76 195

U071 11. Corpus uteri cancer 221 586 0 0 0 0 0 0 0 0 0 18 60 2 300 23 324 80 373 58 312

U072 12. Ovary cancer 225 712 0 0 0 0 0 0 0 0 0 72 1 114 7 908 28 269 81 048 55 065

U073 13. Prostate cancer 373 706 43 150 922 2 494 50 100 106 105 136 849 77 044 373 706 0 0 0 0 0 0

U074 14. Bladder cancer 222 955 139 97 915 6 040 41 207 47 541 47 012 25 958 168 909 59 35 390 3 266 9 756 12 973

U075 15. Lymphomas, multiple myeloma 392 010 1 889 9 162 24 644 40 518 67 541 41 388 26 832 9 179 221 153 1 069 4 914 12 851 21 276 42 345 40 247

U076 16. Leukaemia 430 979 8 844 22 287 59 957 36 218 44 207 28 429 21 790 9 504 231 236 7 540 18 824 31 125 30 759 41 573 30 662

U077 Other malignant neoplasms 1 249 611 9 897 16 465 50 515 97 179 253 549 146 393 87 849 32 382 694 229 8 513 14 111 21 675 60 938 153 473 130 217

U078 B. Other neoplasms 208 384 2 843 3 376 8 694 16 761 31 233 19 422 15 934 6 341 104 605 2 588 4 012 6 468 16 667 27 862 20 359

U079 C. Diabetes mellitus 3 538 712 1 993 3 050 41 095 193 305 489 226 341 370 194 320 58 734 1 323 093 1 439 3 221 46 937 320 091 741 553 564 289

U080 D. Endocrine disorders 728 158 56 398 20 419 39 010 57 342 86 033 41 387 27 953 13 942 342 484 43 501 18 573 44 358 58 175 91 469 49 961

U081 E. Neuropsychiatric conditions 18 967 330 373 842 638 289 3 423 626 2 259 860 1 337 070 374 405 264 100 220 844 8 892 035 355 079 633 364 3 347 879 2 476 022 1 546 961 682 590

U082 1. Unipolar depressive disorders 5 909 976 2 163 169 564 684 606 983 386 038 91 926 16 763 5 650 1 835 214 2 194 460 1 073 249 1 422 068 985 644 308 078

U083 2. Bipolar disorder 1 079 425 2 24 758 443 512 60 081 2 078 447 48 0 530 927 1 21 369 456 329 67 285 2 649 829

U084 3. Schizophrenia 1 271 570 19 90 578 454 480 49 231 10 478 3 473 1 448 672 610 378 49 30 641 473 165 134 879 15 820 3 801

U085 4. Epilepsy 590 732 15 340 54 235 92 057 77 463 51 639 15 613 6 342 1 958 314 647 14 096 49 795 79 923 64 182 41 412 15 627

U086 5. Alcohol use disorders 3 023 154 659 67 702 872 379 943 967 583 761 62 720 11 737 2 574 2 545 498 0 5 746 163 218 163 504 125 343 15 855

U087 6. Alzheimer and other dementias 1 727 702 16 428 8 296 11 098 9 185 41 165 123 604 183 813 190 474 584 063 15 720 8 379 11 663 9 718 52 429 228 667

U088 7. Parkinson disease 120 614 73 57 395 4 189 13 942 13 633 13 110 6 236 51 634 64 92 304 4 546 20 159 17 078

U089 8. Multiple sclerosis 137 094 0 4 386 21 731 18 810 7 682 1 666 1 053 529 55 856 6 5 519 29 754 27 627 12 422 3 531

U090 9. Drug use disorders 765 790 0 6 991 348 534 173 815 41 597 1 134 75 13 572 160 31 6 834 113 933 58 216 13 803 689

U091 10. Post-traumatic stress disorder 309 350 0 1 804 40 875 28 228 16 193 334 221 89 87 745 0 1 775 100 023 80 699 35 068 2 317

U092 11. Obsessive-compulsive disorder 668 780 0 21 866 139 238 93 550 31 816 6 297 2 586 477 295 831 0 44 649 154 747 110 546 46 292 9 742

U093 12. Panic disorder 556 256 0 6 447 164 125 2 274 8 995 902 487 96 183 326 0 8 518 334 018 3 806 21 811 2 605

U094 13. Insomnia (primary) 436 484 0 3 444 48 486 60 540 43 297 17 506 5 326 1 795 180 393 0 3 042 54 689 77 292 70 520 34 048

U095 14. Migraine 615 553 6 655 68 575 86 819 6 638 1 215 30 9 0 169 942 10 814 154 813 170 873 108 900 158 40

U096 15. Mental retardation, lead-caused 482 731 241 420 561 1 244 617 375 54 26 2 244 299 236 059 374 733 574 539 97

Other neuropsychiatric disorders 1 272 120 93 243 115 422 133 969 124 289 96 798 35 067 21 055 10 280 630 123 78 237 97 359 131 258 142 181 102 893 39 584

U098 F. Sense organ diseases 7 429 789 10 457 84 230 211 133 700 170 1 040 906 732 695 370 073 113 683 3 263 346 9 367 76 878 159 206 642 224 1 230 212 1 132 533

U099 1. Glaucoma 701 655 514 2 712 14 571 52 258 94 909 61 139 39 043 18 667 283 813 233 1 131 9 128 50 679 110 201 117 386

U100 2. Cataracts 1 246 252 478 3 447 22 836 89 794 206 809 121 055 68 853 26 267 539 537 184 1 394 11 539 71 722 238 120 182 634

U101 3. Refractive errors 1 570 588 9 023 76 745 102 254 164 568 138 183 148 114 61 625 11 563 712 074 8 647 73 764 97 944 173 035 161 584 208 424

U102 4. Hearing loss, adult onset 2 768 610 0 0 57 803 329 312 437 814 293 300 136 059 28 768 1 283 056 0 0 30 726 302 251 520 923 404 710

U103 5. Macular degeneration and other (g) 1 142 684 442 1 326 13 670 64 237 163 191 109 087 64 494 28 418 444 866 303 590 9 870 44 536 199 384 219 378

U104 G. Cardiovascular diseases 14 953 267 21 187 37 740 247 641 1 074 049 2 589 537 1 688 267 1 338 095 941 959 7 938 475 15 808 30 713 104 086 373 012 976 254 1 201 323

U105 1. Rheumatic heart disease 133 744 430 1 404 8 107 20 547 23 512 6 920 3 301 1 055 65 275 209 1 424 4 474 17 584 21 437 9 904

U106 2. Hypertensive heart disease 693 776 236 494 4 589 27 291 101 829 81 613 78 394 43 027 337 473 89 524 2 850 11 677 34 890 63 467

U107 3. Ischaemic heart disease 7 016 922 688 699 61 811 485 091 1 475 308 905 081 635 426 404 393 3 968 497 492 414 14 393 131 853 503 138 630 652

U108 4. Cerebrovascular disease 4 977 616 5 747 8 583 73 447 255 877 697 612 528 967 467 723 343 313 2 381 269 4 433 6 299 40 171 138 063 298 582 399 013

U109 5. Inflammatory heart diseases (h) 412 474 4 891 2 601 25 701 74 612 72 031 44 337 30 569 17 196 271 939 3 807 1 772 7 339 17 604 22 507 18 162U110 Other cardiovascular diseases 1 718 734 9 194 23 959 73 986 210 631 219 245 121 349 122 683 132 974 914 022 6 778 20 280 34 858 56 230 95 700 80 126

U111 H. Respiratory diseases 3 865 384 164 527 173 525 313 633 273 121 432 262 345 651 327 024 169 026 2 198 769 135 142 208 670 230 987 193 719 305 084 201 470

U112 1. Chronic obstructive pulmonary disea 1 544 909 2 326 2 292 12 646 82 784 234 558 236 154 237 988 119 430 928 179 1 368 3 027 15 916 91 531 164 223 111 435

U113 2. Asthma 1 382 588 89 756 156 265 242 655 98 004 78 617 37 364 29 129 15 125 746 915 80 665 196 193 174 612 50 329 53 285 33 625

U114 Other respiratory diseases 937 888 72 445 14 968 58 332 92 334 119 088 72 132 59 906 34 471 523 675 53 110 9 450 40 460 51 859 87 576 56 409

U115 I. Digestive diseases 3 081 744 11 376 8 798 94 998 507 961 698 540 257 920 154 363 62 042 1 795 997 9 132 6 290 50 230 264 606 376 093 203 610

U116 1. Peptic ulcer disease 247 063 109 437 9 439 32 434 50 327 22 614 17 842 9 802 143 004 60 300 3 601 15 506 25 699 16 393

U117 2. Cirrhosis of the liver 1 297 876 327 1 993 27 576 239 681 398 274 135 598 62 246 14 884 880 581 266 483 7 367 83 311 158 589 80 418

U118 3. Appendicitis 24 028 160 1 062 3 067 3 589 3 168 1 275 1 033 528 13 882 172 627 1 150 2 572 2 171 1 323

U119 Other digestive diseases 1 512 778 10 779 5 305 54 915 232 256 246 771 98 434 73 242 36 828 758 530 8 633 4 879 38 112 163 216 189 635 105 477

U120 J. Genitourinary diseases 1 147 636 8 954 11 054 47 622 78 836 375 077 109 612 83 793 48 740 763 687 6 622 12 454 31 831 51 523 92 571 72 999

U121 1. Nephritis and nephrosis 630 735 6 224 9 089 36 135 64 981 87 428 64 419 49 797 27 677 345 750 4 715 9 947 17 620 37 070 68 189 57 565

U122 2. Benign prostatic hypertrophy 331 115 0 0 36 189 263 100 30 776 23 241 13 774 331 115 0 0 0 0 0 0

U123 Other genitourinary system diseases 185 786 2 730 1 965 11 450 13 667 24 549 14 416 10 755 7 289 86 822 1 907 2 507 14 211 14 454 24 382 15 433

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U124 K. Skin diseases 440 657 9 108 14 126 40 120 49 707 42 780 18 965 12 733 7 558 195 097 8 998 11 704 41 086 49 936 56 945 29 492

U125 L. Musculoskeletal diseases 3 917 408 6 677 38 649 159 730 418 536 476 747 195 186 97 754 31 685 1 424 965 5 077 66 537 249 694 528 576 819 556 460 048

U126 1. Rheumatoid arthritis 729 724 869 13 114 35 601 44 331 44 960 18 129 8 619 3 264 168 887 1 923 39 249 143 844 149 297 135 433 52 501

U127 2. Osteoarthritis 2 305 387 18 266 54 104 243 088 317 858 143 145 71 403 17 765 847 648 1 320 38 240 277 290 558 920 342 899

U128 3. Gout 165 792 1 87 6 455 69 226 55 852 9 111 1 987 910 143 628 5 18 1 290 8 389 6 863 3 148

U129 4. Low back pain 219 328 4 336 14 990 23 986 35 507 25 540 6 595 2 582 915 114 452 2 097 18 163 16 149 28 458 26 906 8 340

U130 Other musculoskeletal disorders 497 178 1 453 10 192 39 584 26 384 32 537 18 206 13 163 8 832 150 350 1 051 8 788 50 171 65 142 91 435 53 160

U131 M. Congenital anomalies 1 057 762 519 738 12 077 19 006 10 782 8 796 3 495 2 514 1 223 577 630 441 686 10 864 9 878 7 642 6 575 2 030

U132 1. Abdominal wall defect 9 564 5 249 7 9 3 1 0 0 2 5 272 4 274 5 4 2 2 0

U133 2. Anencephaly 15 706 7 460 8 10 2 1 0 0 4 7 487 8 179 14 11 5 7 2

U134 3. Anorectal atresia 1 885 1 109 34 27 26 0 0 0 0 1 196 686 1 1 0 0 0

U135 4. Cleft lip 20 298 4 533 230 1 354 2 335 3 247 2 021 1 575 756 16 051 4 247 0 0 0 0 0

U136 5. Cleft palate 6 939 3 531 1 1 0 0 0 0 0 3 533 3 390 16 0 0 0 0

U137 6. Oesophageal atresia 5 106 2 584 30 3 2 3 1 0 6 2 628 2 434 25 5 5 4 1

U138 7. Renal agenesis 6 091 3 751 29 66 8 37 21 1 6 3 919 1 345 90 453 172 108 3

U139 8. Down syndrome 218 724 116 276 629 1 187 1 007 873 147 1 9 120 129 95 107 655 725 918 998 177

U140 9. Congenital heart anomalies 464 226 225 511 5 235 10 209 4 802 2 272 628 461 202 249 320 196 216 5 003 5 396 3 958 2 865 844

U141 10. Spina bifida 71 290 34 127 859 744 173 78 5 2 18 36 008 33 891 739 436 112 100 2

U142 Other Congenital anomalies 237 934 115 605 5 016 5 397 2 424 2 283 671 473 219 132 088 91 919 4 316 2 847 2 470 2 490 1 001

U143 N. Oral conditions 1 053 319 25 787 105 014 78 857 46 235 103 029 99 449 16 458 3 346 478 174 24 727 101 195 79 131 50 092 128 148 141 981

U144 1. Dental caries 572 288 25 216 104 905 62 807 29 331 36 993 11 284 4 940 2 406 277 881 24 191 100 997 62 325 31 268 44 355 17 568

U145 2. Periodontal disease 36 038 0 0 2 985 6 471 4 858 1 517 654 276 16 761 0 42 2 957 6 909 5 716 2 089

U146 3. Edentulism 436 522 0 0 12 572 9 423 60 222 86 274 10 544 531 179 565 0 0 13 181 10 804 77 319 121 793

U147 Other oral diseases 8 471 570 109 493 1 010 956 375 320 134 3 966 536 155 667 1 111 757 530

U148 III.Injuries 12 212 667 181 605 398 593 4 314 007 2 597 715 1 169 479 263 743 153 115 71 784 9 150 040 131 798 267 822 947 217 732 298 491 907 252 372

U149 A. Unintentional injuries 5 892 270 162 508 302 635 1 486 135 973 328 600 800 164 873 117 665 56 787 3 864 730 115 669 209 258 590 158 386 398 316 405 205 357

U150 1. Road traffic accidents 2 773 640 40 191 129 241 947 094 420 684 203 727 57 230 28 723 8 068 1 834 958 36 967 107 322 394 502 205 644 120 270 43 446

U151 2. Poisonings 326 361 3 360 2 432 53 676 71 261 45 961 10 606 5 921 1 872 195 090 2 622 3 027 19 358 30 067 37 803 28 335

U152 3. Falls 654 576 18 973 37 570 86 060 90 695 73 789 26 844 32 365 23 955 390 251 14 429 26 755 34 008 29 768 29 267 41 347

U153 4. Fires 207 852 12 512 10 222 25 782 36 819 20 055 4 801 5 139 2 430 117 759 8 514 7 873 15 902 18 554 16 217 11 304

U154 5. Drownings 214 581 12 292 21 421 53 362 40 035 26 141 6 177 3 791 1 032 164 250 8 052 9 312 9 625 7 264 7 917 4 663

U155 6. Other unintentional injuries 1 715 259 75 179 101 749 320 160 313 834 231 127 59 215 41 727 19 429 1 162 421 45 084 54 970 116 763 95 100 104 931 76 261

U156 B. Intentional injuries 6 320 398 19 096 95 959 2 827 873 1 624 387 568 679 98 870 35 450 14 997 5 285 310 16 129 58 563 357 059 345 900 175 502 47 015

U157 1. Self-inflicted injuries 1 867 985 0 25 851 667 748 481 850 252 334 49 877 21 587 8 635 1 507 883 0 20 025 130 262 103 236 66 368 22 101

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Female70-79 80+ Total

6 896 276 3 196 598 43 087 194

207 247 100 892 4 446 891

103 505 24 749 3 009 966 5 190 1 507 161 258 1 036 392 192 218

202 71 12 444 0 0 114 634

12 0 62 960 822 321 2 179

44 672 86 2 207 416 15 234 6 945 165 412

141 65 8 976 0 0 6 405 8 8 77

16 1 158 0 0 1 786

117 56 551 2 610 594 24 637 1 460 298 7 628 1 470 143 6 318

825 197 54 647 1 469 587 26 104

2 0 202 1 078 546 15 947

364 30 8 699 9 2 417

10 3 626 7 7 213

38 19 980 11 4 520 20 8 955

636 183 3 014 349 106 19 245

0 0 4 696 0 0 5 864

346 105 8 651 2 0 35

28 345 13 617 131 068 82 750 65 568 356 152 81 418 65 002 323 139 1 290 553 19 767

43 13 13 246 0 0 259 146 0 0 9 229 0 0 36 922 0 0 13 558 0 0 30 726 0 0 51 855 0 0 116 855 0 0 486 888

0 0 193 862

0 0 159 057

0 0 133 969 20 992 10 575 334 739 1 664 1 926 70 497

12 2 81 580 7 2 714

17 793 7 655 172 627 1 516 991 9 321

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6 525 924 3 019 597 35 577 6761 021 179 272 811 4 486 483

14 838 4 816 63 634 20 047 5 891 80 594

110 201 29 983 355 819 152 766 47 617 477 658 38 022 9 820 136 285 55 845 15 745 164 748

113 138 20 929 492 479 13 788 6 389 65 393

142 583 40 516 848 718 49 363 10 820 373 831 46 644 10 556 221 586 43 873 8 362 225 712

0 0 0 19 721 7 845 54 046 39 324 8 831 170 857 31 239 8 021 199 743

129 786 36 670 555 381 19 010 6 816 103 780

417 056 121 036 2 215 620 50 748 28 889 385 674

578 486 454 914 10 075 295 72 955 18 306 4 074 762

13 23 548 498 2 458 379 661 193 8 664 2 386 276 085 3 362 628 477 657

412 271 404 790 1 143 638 19 921 6 816 68 980 1 705 675 81 238

109 16 193 630 1 352 371 221 605 5 833 1 141 372 949 1 902 269 372 930

12 739 3 761 256 091 12 0 445 611 45 11 238 431

35 145 15 340 641 997 737 722 178 301 4 166 443 96 041 33 043 417 842

151 883 49 239 706 714 117 305 17 811 858 514 197 858 29 087 1 485 554 174 635 49 122 697 818

2 743 556 1 570 040 7 014 791 10 984 2 452 68 469

161 077 81 729 356 3031 148 204 619 279 3 048 4251 115 586 594 200 2 596 347

44 387 24 958 140 535 263 318 247 422 804 712 253 661 137 882 1 666 615 149 230 80 001 616 730 34 179 12 785 635 673 70 252 45 096 414 212

271 822 103 964 1 285 747 28 180 14 320 104 059 72 902 13 958 417 295 1 580 551 10 145

169 159 75 136 754 247 77 106 38 843 383 948 60 230 29 648 284 985

0 0 0 16 875 9 194 98 963

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27 996 19 403 245 561 283 596 79 359 2 492 443 29 169 9 422 560 837

201 562 38 507 1 457 739 1 899 551 22 164 3 806 957 104 876

47 161 29 921 346 828 1 063 394 480 132

4 0 4 291 1 0 8 219 0 0 689 0 0 4 247 0 0 3 406 1 4 2 478 1 0 2 172

16 0 98 595 479 145 214 907

2 0 35 282 559 245 105 846

42 926 6 946 575 145 10 141 3 561 294 407 1 130 433 19 277

31 145 2 713 256 956 509 239 4 505

163 104 76 110 3 062 627 135 871 68 424 2 027 540

25 460 5 071 938 682 8 335 1 723 131 271

49 530 39 221 264 324 8 214 3 514 90 093 2 712 786 50 331

41 620 18 110 552 839 27 233 7 685 1 035 087 14 361 3 750 360 102

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GBD 2004: Projected DALYs by age, sex and cause for the year 2030, optimistic scenarioLower middle income countries (a)

Male FemaleCode Cause Total 0-4 5-14 15-29 30-44 45-59 60-69 70-79 80+ Total 0-4 5-14 15-29 30-44 45-59U000 All Causes 399 689 774 15 019 666 9 346 037 40 343 435 37 604 980 51 990 631 35 909 019 20 137 904 7 963 366 218 315 038 13 191 219 7 942 575 25 927 282 27 082 908 36 383 819

U001 I.29 558 020 7 825 559 633 454 1 576 609 2 195 613 1 565 849 762 343 528 841 274 568 15 362 835 6 613 549 660 523 2 254 270 1 934 091 1 022 365

U002 A. Infectious and parasitic diseases 11 155 689 1 149 415 360 613 1 243 895 1 742 397 1 073 665 389 371 205 935 72 591 6 237 881 906 474 328 780 1 038 594 1 250 643 665 456

U003 1. Tuberculosis 1 617 387 19 260 17 968 157 972 298 735 279 981 147 573 60 206 14 672 996 368 17 425 20 358 126 622 162 827 143 887

U006 2. STDs excluding HIV 742 193 32 836 1 607 98 737 63 076 10 232 4 701 4 148 2 307 217 643 28 660 6 938 355 821 109 240 12 732

U005 a. Syphilis 71 198 8 612 153 11 297 9 484 3 963 2 178 2 457 1 552 39 696 6 513 228 11 177 7 869 987

U006 b. Chlamydia 371 772 115 516 27 728 9 832 315 41 0 0 38 547 104 5 266 265 879 54 223 6 139

U007 c. Gonorrhoea 278 325 23 998 917 59 592 42 571 1 041 174 0 0 128 293 21 878 1 427 78 212 45 859 1 628

U008 d. Other STDs 20 898 112 20 120 1 189 4 912 2 308 1 691 756 11 108 165 17 553 1 289 3 978

U009 3. HIV/AIDS 3 142 391 29 946 35 638 589 897 860 659 319 481 28 026 1 553 25 1 865 225 30 903 39 376 275 681 690 146 191 624

U010 4. Diarrhoeal diseases 2 454 359 650 466 101 289 158 822 188 750 129 505 65 576 39 708 18 289 1 352 406 514 339 88 420 121 014 122 266 109 220

U011 5. Childhood-cluster diseases 248 940 104 290 16 527 13 433 6 454 4 606 2 555 582 99 148 546 73 718 14 452 6 124 1 981 1 444

U012 a. Pertussis 87 711 45 855 2 683 41 9 0 10 4 2 48 605 36 385 2 632 42 48 0

U013 b. Poliomyelitis (c) 648 0 20 203 146 68 8 7 10 462 0 20 26 81 38

U016 c. Diphtheria 1 423 690 60 40 0 16 6 4 8 824 514 32 28 6 6

U015 d. Measles 95 323 31 829 13 306 8 829 0 0 3 0 7 53 974 24 759 11 454 4 997 23 0

U016 e. Tetanus 63 834 25 916 458 4 319 6 299 4 522 2 527 567 72 44 681 12 060 314 1 029 1 823 1 400

U017 6. Meningitis 286 516 69 062 13 432 22 213 23 790 16 484 8 718 4 378 1 780 159 857 53 205 15 498 15 901 11 874 14 832

U018 7. Hepatitis B (d) 183 743 3 473 1 315 10 026 30 928 64 832 18 573 6 416 1 478 137 042 2 578 1 129 3 079 5 662 13 477

U019 Hepatitis C (d) 85 306 1 547 408 3 464 13 025 30 658 8 994 3 099 751 61 946 1 143 411 1 040 2 148 7 084

U020 8. Malaria 453 713 137 351 39 702 26 784 23 472 14 806 4 472 2 255 555 249 397 104 072 34 253 23 189 19 186 14 172

U021 9. Tropical-cluster diseases 300 905 5 899 22 544 65 974 51 432 42 916 11 353 5 360 1 339 206 817 4 386 9 331 27 257 13 756 23 345

U022 a. Trypanosomiasis 22 314 681 4 390 4 108 3 656 2 420 169 76 4 15 503 510 2 016 2 028 1 301 839

U023 b. Chagas disease 100 622 0 7 21 171 12 531 14 751 7 292 3 929 1 114 60 795 8 5 14 436 3 887 9 124

U026 c. Schistosomiasis 39 969 1 740 5 687 3 531 6 839 5 487 2 215 626 73 26 199 1 172 3 700 1 664 2 925 2 535

U025 d. Leishmaniasis 26 900 1 709 3 390 5 940 5 015 2 297 415 286 60 19 112 1 082 1 684 2 000 1 376 1 255

U026 e. lymphatic filariasis 110 100 1 746 9 019 31 084 23 187 17 771 1 231 433 85 84 556 1 586 1 879 7 042 4 182 9 519

U027 f. Onchocerciasis 1 001 24 50 139 204 191 30 10 3 652 28 47 88 84 73

U028 10. Leprosy 8 069 43 617 650 975 845 629 1 104 137 5 000 47 596 615 706 678

U029 11. Dengue 23 787 2 529 7 915 652 550 231 93 77 53 12 101 1 568 8 461 720 349 216

U030 12. Japanese encephalitis 32 742 4 227 6 599 1 331 972 422 201 201 108 14 061 5 031 10 576 1 419 558 337

U031 13. Trachoma 161 599 11 28 412 5 629 12 358 10 984 7 283 2 066 38 772 36 71 817 11 556 30 311

U032 14. Intestinal nematode infections 290 779 20 040 66 148 21 724 22 872 16 556 6 588 2 951 860 157 738 17 524 57 552 16 206 14 899 14 045

U033 a. Ascariasis 89 311 11 850 35 992 155 36 22 0 12 0 48 068 10 329 30 824 4 25 5

U036 b. Trichuriasis 58 959 7 121 23 977 8 156 7 3 1 0 31 274 6 250 21 382 6 6 6

U035 c. Hookworm disease 139 713 14 6 052 21 528 22 485 16 452 6 441 2 926 855 76 754 11 5 318 16 179 14 859 13 990

U036 Other intestinal infections 2 796 1 054 127 32 195 75 143 11 4 1 642 933 27 17 9 44

U037 Other infectious diseases 1 137 611 69 082 32 238 71 852 151 316 129 807 70 381 66 643 28 085 619 404 53 339 28 922 63 525 83 596 88 080

U038 B. Respiratory infections 4 863 604 1 034 641 150 097 165 919 288 181 358 925 303 413 276 026 180 427 2 757 629 799 873 140 889 102 575 108 736 177 799

U039 1. Lower respiratory infections 4 546 420 997 763 99 423 146 720 265 361 338 240 291 527 269 972 175 626 2 584 631 767 853 95 443 87 009 93 345 166 587

U040 2. Upper respiratory infections 207 488 23 061 8 793 17 814 22 067 20 330 11 519 5 997 4 707 114 288 20 038 8 753 14 289 14 827 10 950

U041 3. Otitis media 109 696 13 818 41 880 1 386 754 355 367 57 94 58 711 11 982 36 693 1 277 564 262

U042 C. Maternal conditions 1 437 278 0 0 0 0 0 0 0 0 0 0 78 315 932 720 418 989 7 254

U043 1. Maternal haemorrhage 99 882 0 0 0 0 0 0 0 0 0 0 190 46 995 51 325 1 371

U044 2. Maternal sepsis 253 915 0 0 0 0 0 0 0 0 0 0 273 197 338 55 909 395

U045 3. Hypertensive disorders 58 183 0 0 0 0 0 0 0 0 0 0 1 067 30 779 25 074 1 263

U046 4. Obstructed labour 176 188 0 0 0 0 0 0 0 0 0 0 0 128 071 47 633 483

U047 5. Abortion 260 572 0 0 0 0 0 0 0 0 0 0 75 434 165 224 19 722 193

U048 Other maternal conditions 588 540 0 0 0 0 0 0 0 0 0 0 1 352 364 313 219 327 3 548

U049 D. Perinatal conditions (e) 9 378 251 5 015 120 41 12 26 31 0 0 5 5 015 236 4 362 922 73 5 6 6

U050 1. Prematurity and low birth weight 3 287 938 1 765 934 0 0 0 3 0 0 0 1 765 937 1 521 941 60 0 0 0

U051 2. Birth asphyxia and birth trauma 3 407 468 1 789 824 22 12 21 28 0 0 5 1 789 914 1 617 522 13 5 6 6

U052 3. 2 682 845 1 459 362 19 0 4 0 0 0 0 1 459 386 1 223 460 0 0 0 0

U053 E. Nutritional deficiencies 2 723 199 626 382 122 703 166 782 165 009 133 228 69 559 46 881 21 545 1 352 088 544 279 112 466 180 377 155 716 171 851

U056 1. Protein-energy malnutrition 914 331 428 897 4 883 9 443 13 009 10 374 7 046 8 783 7 020 489 455 367 804 5 359 3 895 5 514 6 566

U055 2. Iodine deficiency 319 154 129 288 37 760 14 3 61 28 65 0 167 220 117 663 33 488 86 65 120

U056 3. Vitamin A deficiency 8 176 4 194 178 180 45 51 0 2 7 4 657 3 071 155 12 18 123

U057 4. Iron-deficiency anaemia 1 449 709 60 360 79 232 155 832 150 400 121 140 61 623 36 503 13 863 678 953 52 795 72 479 174 959 148 413 162 397U058 Other nutritional disorders 31 829 3 642 649 1 313 1 553 1 601 862 1 528 654 11 803 2 946 985 1 424 1 706 2 644

Communicable, maternal, perinatal and nutritional conditions

Neonatal infections and other conditions (f)

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U059 II. Noncommunicable diseases 308 133 453 4 883 204 5 457 638 20 986 560 26 741 390 45 965 228 33 182 622 18 675 663 7 394 878 163 287 184 4 534 849 4 950 880 17 820 452 20 308 531 31 692 005

U060 A. Malignant neoplasms 39 732 860 133 644 289 347 963 250 2 284 271 8 171 186 7 703 271 3 787 230 913 073 24 245 271 161 942 231 240 419 888 1 852 749 4 911 898

U061 1. Mouth and oropharynx cancers 1 194 948 683 3 812 42 355 121 427 397 348 244 778 94 569 22 583 927 554 1 865 1 732 4 970 28 716 91 231

U062 2. Oesophagus cancer 3 353 602 117 353 11 832 122 457 821 164 944 008 421 176 79 981 2 401 088 67 290 6 063 46 869 249 010

U063 3. Stomach cancer 5 235 783 494 3 610 57 856 259 555 1 350 480 1 256 343 626 806 176 960 3 732 105 92 1 105 29 278 157 319 404 318

U066 4. Colon and rectum cancers 2 456 154 109 2 210 64 664 196 007 440 993 406 247 244 337 84 558 1 439 125 80 546 14 536 128 153 301 474

U065 5. Liver cancer 4 584 887 3 919 5 207 90 288 441 897 1 397 081 1 085 284 420 743 74 671 3 519 090 6 601 4 274 26 751 89 437 293 467

U066 6. Pancreas cancer 811 865 28 233 2 450 52 939 184 169 162 180 83 912 21 938 507 849 8 107 2 389 21 938 67 296

U067 7. Trachea, bronchus, lung cancers 10 048 253 1 4 0 421 764 2 283 624 2 476 097 1 150 731 203 195 6 535 416 0 2 0 247 177 1 087 734

U068 8. Melanoma and other skin cancers 153 124 154 531 6 199 11 503 26 674 18 194 9 327 3 918 76 499 373 1 120 3 871 13 562 20 440

U069 9. Breast cancer 2 349 128 0 0 0 100 466 251 243 84 1 143 186 1 156 18 681 432 478 1 068 185

U070 10. Cervix uteri cancer 1 028 606 0 0 0 0 0 0 0 0 0 91 647 87 850 115 109 425 286

U071 11. Corpus uteri cancer 238 018 0 0 0 0 0 0 0 0 0 16 38 2 238 26 324 92 971

U072 12. Ovary cancer 479 229 0 0 0 0 0 0 0 0 0 558 8 366 25 493 86 284 172 043

U073 13. Prostate cancer 730 877 223 845 1 492 4 899 97 793 251 329 280 817 93 480 730 877 0 0 0 0 0

U076 14. Bladder cancer 784 399 543 605 8 057 41 335 173 311 186 390 137 198 49 672 597 111 370 224 2 426 19 422 44 461

U075 15. Lymphomas, multiple myeloma 1 443 777 12 622 65 302 172 560 203 372 250 919 160 063 72 852 22 117 959 808 10 364 39 450 46 687 80 109 110 639

U076 16. Leukaemia 1 845 823 55 840 143 606 414 046 163 545 166 890 114 021 54 775 16 386 1 129 108 68 948 117 239 120 561 143 254 139 060

U077 Other malignant neoplasms 2 994 386 58 911 63 028 91 451 243 472 580 275 398 086 189 745 63 529 1 688 498 72 324 54 942 28 091 216 599 344 283

U078 B. Other neoplasms 755 715 11 722 22 048 60 395 86 029 105 768 74 690 41 128 10 908 412 687 14 608 20 793 22 304 53 341 116 959

U079 C. Diabetes mellitus 10 058 903 4 503 10 268 146 344 775 600 1 839 892 1 106 192 548 415 169 798 4 601 012 3 766 13 474 113 080 716 495 1 681 118

U080 D. Endocrine disorders 2 714 228 280 397 61 190 155 455 258 422 304 484 189 944 105 537 45 053 1 400 482 267 129 57 867 168 569 189 189 224 848

U081 E. Neuropsychiatric conditions 79 133 712 1 559 156 2 799 849 14 492 792 10 082 917 6 193 546 2 163 030 1 189 298 670 322 39 150 910 1 433 200 2 343 722 13 358 690 8 857 250 6 717 901

U082 1. Unipolar depressive disorders 27 440 550 81 868 915 3 015 358 3 124 010 2 175 802 621 936 88 810 20 042 9 914 954 55 910 763 4 043 430 5 585 163 4 874 201

U083 2. Bipolar disorder 4 963 317 49 111 364 2 051 884 312 907 10 539 2 662 33 1 2 489 441 36 116 947 2 016 182 323 203 13 044

U086 3. Schizophrenia 6 271 015 216 484 256 2 218 015 395 831 93 607 18 151 4 637 1 028 3 215 740 151 131 052 2 227 987 486 765 164 371

U085 4. Epilepsy 1 998 951 47 394 194 340 364 889 279 749 156 770 49 848 17 946 4 770 1 115 706 42 418 162 806 264 164 206 317 126 467

U086 5. Alcohol use disorders 11 603 916 670 373 881 3 243 255 4 087 539 2 560 510 380 165 54 615 12 709 10 713 343 321 25 627 310 712 284 733 229 171

U087 6. Alzheimer and other dementias 7 161 570 79 823 41 995 53 859 50 977 211 083 773 779 825 320 558 724 2 595 560 72 605 40 493 51 481 46 103 221 498

U088 7. Parkinson disease 649 188 1 905 1 411 9 716 31 071 98 830 88 872 78 655 30 047 340 507 1 311 1 679 2 151 15 846 58 129

U089 8. Multiple sclerosis 551 314 130 23 289 104 325 79 012 22 276 4 568 1 329 621 235 550 129 33 907 132 998 108 444 29 634

U090 9. Drug use disorders 2 895 695 223 69 074 1 208 478 721 766 258 658 11 681 1 464 375 2 271 719 120 35 491 338 835 187 114 58 414

U091 10. Post-traumatic stress disorder 1 417 095 4 10 832 168 344 136 147 78 067 1 974 984 248 396 601 3 7 083 434 781 387 962 173 569

U092 11. Obsessive-compulsive disorder 1 898 079 0 69 096 387 065 245 739 85 832 14 794 2 994 648 806 169 0 79 087 509 447 331 099 140 461

U093 12. Panic disorder 2 462 360 0 35 314 737 893 9 612 43 004 5 129 2 309 272 833 532 0 36 272 1 461 251 15 911 93 463

U096 13. Insomnia (primary) 1 352 509 0 18 453 113 090 138 707 106 584 48 791 16 522 3 990 446 139 0 14 747 162 409 272 881 254 539

U095 14. Migraine 2 406 533 15 996 201 457 386 315 27 268 3 111 173 40 1 634 361 38 817 536 642 1 013 436 181 831 1 116

U096 15. Mental retardation, lead-caused 2 181 791 1 102 185 6 205 15 457 4 576 1 775 448 131 29 1 130 805 1 036 081 5 624 3 479 3 481 1 569

Other neuropsychiatric disorders 3 879 829 310 481 289 966 414 848 438 006 287 096 140 059 93 509 36 818 2 010 782 241 154 205 501 385 947 420 398 278 254

U098 F. Sense organ diseases 45 103 973 99 228 817 614 1 404 229 4 532 233 6 986 281 5 344 615 1 891 823 376 264 21 452 289 94 526 727 590 1 105 730 3 782 017 6 994 231

U099 1. Glaucoma 3 476 534 1 471 10 361 55 306 214 917 552 453 368 699 150 858 48 270 1 402 335 1 633 11 407 62 175 233 158 711 044

U100 2. Cataracts 8 660 463 2 147 18 024 117 865 599 884 1 747 464 1 162 648 483 910 124 421 4 256 363 4 601 19 983 89 962 383 977 1 439 197

U101 3. Refractive errors 13 591 277 94 503 778 729 896 643 1 336 477 1 220 878 1 709 621 576 911 58 495 6 672 257 86 602 691 097 735 705 1 144 460 1 181 505

U102 4. Hearing loss, adult onset 13 480 890 0 0 243 457 1 979 975 2 542 388 1 454 113 435 692 65 547 6 721 172 0 0 157 964 1 580 541 2 456 211

U103 5. Macular degeneration and other (g) 5 894 809 1 108 10 500 90 957 400 980 923 099 649 534 244 453 79 532 2 400 164 1 690 5 102 59 924 439 880 1 206 273

U106 G. Cardiovascular diseases 57 980 487 181 803 105 935 783 792 3 111 362 8 906 763 8 683 504 6 454 464 3 099 874 31 327 497 171 546 93 080 258 544 971 195 3 915 684

U105 1. Rheumatic heart disease 1 209 236 5 598 12 348 62 395 130 901 162 486 101 564 56 137 18 094 549 522 5 075 11 479 29 284 61 900 126 062

U106 2. Hypertensive heart disease 4 589 501 4 401 4 099 25 073 185 806 670 242 709 206 585 874 295 355 2 480 056 4 066 2 939 8 759 38 550 209 635

U107 3. Ischaemic heart disease 20 149 287 7 562 5 895 231 810 1 283 603 3 763 419 3 083 612 2 076 950 903 116 11 355 967 5 349 3 768 57 774 377 946 1 574 569

U108 4. Cerebrovascular disease 23 921 530 35 803 39 115 239 848 880 625 3 312 895 3 914 102 2 984 668 1 333 962 12 741 018 33 333 29 097 83 772 336 815 1 457 948

U109 5. Inflammatory heart diseases (h) 1 630 806 28 562 7 649 55 849 152 318 205 252 197 417 155 082 96 126 898 256 24 777 5 973 16 560 38 547 97 941U110 Other cardiovascular diseases 6 480 128 99 877 36 830 168 817 478 109 792 468 677 603 595 753 453 220 3 302 679 98 946 39 824 62 396 117 437 449 530

U111 H. Respiratory diseases 32 187 463 446 050 702 306 1 382 931 1 875 495 5 586 164 4 641 990 3 271 018 1 642 604 19 548 559 390 770 788 806 819 238 800 335 1 572 661

U112 1. Chronic obstructive pulmonary disease 22 525 259 11 179 5 486 37 469 817 792 4 524 545 4 030 041 2 909 736 1 442 084 13 778 333 8 422 4 673 31 788 399 493 1 088 117

U113 2. Asthma 5 318 370 319 557 613 450 1 034 619 448 234 390 220 152 904 64 828 21 106 3 044 918 274 439 736 565 617 866 182 955 230 162

U116 Other respiratory diseases 4 343 833 115 313 83 371 310 842 609 470 671 399 459 044 296 453 179 415 2 725 308 107 909 47 569 169 585 217 886 254 382

U115 I. Digestive diseases 8 968 542 82 997 32 868 270 645 1 277 185 2 758 994 914 159 509 651 165 090 6 011 590 90 844 24 378 130 796 433 451 857 851

U116 1. Peptic ulcer disease 1 090 118 1 703 5 433 32 589 139 979 342 492 124 643 90 980 33 335 771 154 5 648 911 8 572 36 156 86 054

U117 2. Cirrhosis of the liver 3 444 243 6 378 6 382 70 584 515 152 1 290 846 393 839 193 744 43 071 2 519 996 5 000 4 055 19 944 116 950 311 447

U118 3. Appendicitis 84 810 649 2 593 7 360 11 853 21 875 5 636 3 919 1 829 55 716 607 2 155 2 966 5 074 5 132

U119 Other digestive diseases 4 349 370 74 267 18 460 160 111 610 200 1 103 780 390 041 221 008 86 855 2 664 722 79 590 17 257 99 314 275 272 455 218

U120 J. Genitourinary diseases 6 191 362 51 856 35 594 239 295 453 065 2 149 885 656 395 384 932 170 962 4 141 984 50 111 34 408 122 272 277 427 569 343

U121 1. Nephritis and nephrosis 3 171 346 34 077 28 720 170 986 327 245 525 379 387 199 236 389 100 205 1 810 200 36 421 28 120 66 456 134 206 371 260

U122 2. Benign prostatic hypertrophy 1 716 988 0 0 20 3 088 1 456 832 147 308 74 357 35 384 1 716 988 0 0 0 0 0

U123 Other genitourinary system diseases 1 303 028 17 778 6 874 68 289 122 732 167 674 121 889 74 186 35 373 614 796 13 690 6 288 55 817 143 222 198 083

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U126 K. Skin diseases 1 746 863 52 472 77 429 168 959 158 729 163 058 76 379 45 438 24 788 767 252 44 571 65 623 179 567 205 199 214 847

U125 L. Musculoskeletal diseases 15 681 330 36 442 177 765 578 202 1 641 585 2 289 929 1 166 655 374 493 93 529 6 358 600 32 043 233 125 823 840 1 968 323 3 342 393

U126 1. Rheumatoid arthritis 2 391 207 2 668 31 361 82 299 146 109 228 545 108 303 38 031 9 602 646 916 9 267 86 444 262 055 366 951 587 589

U127 2. Osteoarthritis 8 752 080 92 1 531 138 101 686 224 1 326 718 797 352 219 797 35 370 3 205 185 72 1 372 294 500 1 157 874 2 227 702

U128 3. Gout 1 253 782 9 57 43 314 548 552 420 915 77 809 17 602 3 531 1 111 790 8 15 6 666 62 664 41 515

U129 4. Low back pain 1 096 203 25 039 84 678 115 518 143 476 140 723 43 677 13 197 3 105 569 415 12 671 99 033 76 801 141 475 129 932

U130 Other musculoskeletal disorders 2 188 058 8 634 60 138 198 970 117 224 173 028 139 514 85 865 41 922 825 295 10 025 46 260 183 818 239 360 355 656

U131 M. Congenital anomalies 3 667 537 1 723 027 55 366 88 764 34 588 18 796 5 658 4 362 1 969 1 932 530 1 581 335 59 737 46 453 23 562 12 282

U132 1. Abdominal wall defect 19 197 9 701 202 393 129 66 8 23 21 10 543 8 057 270 161 69 22

U133 2. Anencephaly 62 646 30 027 757 1 698 457 223 44 64 69 33 338 26 979 1 102 725 261 80

U136 3. Anorectal atresia 6 599 3 216 89 187 49 23 6 8 3 3 580 2 724 105 78 30 9

U135 4. Cleft lip 61 977 32 428 6 9 1 0 0 0 0 32 445 29 474 54 2 1 1

U136 5. Cleft palate 36 777 18 416 24 40 10 2 0 1 0 18 493 18 201 46 11 7 19

U137 6. Oesophageal atresia 9 715 4 920 66 108 35 19 5 6 2 5 161 4 154 197 97 46 43

U138 7. Renal agenesis 7 578 3 766 98 135 65 124 89 4 1 4 283 2 988 92 57 33 69

U139 8. Down syndrome 863 557 458 585 2 388 5 780 2 468 1 479 265 96 52 471 113 382 909 3 116 3 179 1 339 1 568

U160 9. Congenital heart anomalies 1 688 053 759 348 28 863 47 885 18 373 8 774 2 632 2 277 943 869 095 736 424 31 684 26 840 13 221 5 224

U161 10. Spina bifida 192 576 90 122 3 082 3 630 535 473 94 77 31 98 044 89 691 2 597 1 373 536 101

U162 Other Congenital anomalies 718 862 312 498 19 790 28 899 12 467 7 611 2 516 1 806 846 386 434 279 734 20 474 13 929 8 019 5 147

U163 N. Oral conditions 4 210 478 219 908 270 058 251 507 169 908 490 483 456 140 67 874 10 643 1 936 521 198 458 257 038 251 480 177 997 559 990

U166 1. Dental caries 2 169 435 215 907 269 123 184 781 106 188 193 151 67 642 25 201 7 724 1 069 716 194 916 255 933 182 186 109 278 213 338

U165 2. Periodontal disease 111 526 0 31 11 057 24 233 12 199 4 103 1 589 523 53 735 0 76 10 560 24 286 13 905

U166 3. Edentulism 1 885 199 0 0 53 782 36 631 281 246 382 247 39 773 1 678 795 358 0 0 54 877 39 232 327 382

U167 Other oral diseases 44 317 4 001 904 1 886 2 856 3 887 2 148 1 311 719 17 712 3 541 1 029 3 857 5 201 5 365

U168 III.Injuries 61 998 303 2 310 903 3 254 945 17 780 267 8 667 978 4 459 554 1 964 054 933 399 293 920 39 665 020 2 042 821 2 331 172 5 852 560 4 840 287 3 669 449

U169 A. Unintentional injuries 44 272 591 2 226 410 2 874 060 10 341 500 5 079 976 3 290 575 1 305 714 718 954 237 393 26 074 582 1 985 195 2 056 947 5 087 359 3 671 247 2 634 572

U150 1. Road traffic accidents 26 059 394 589 282 1 038 076 8 106 996 3 030 328 1 955 305 765 853 328 003 77 777 15 891 618 645 672 882 076 3 491 237 2 578 801 1 683 822

U151 2. Poisonings 872 982 54 722 21 742 95 964 131 803 100 537 39 855 22 929 7 899 475 451 47 272 24 545 75 996 71 544 52 503

U152 3. Falls 3 893 334 215 708 327 879 387 285 440 261 324 146 145 809 155 164 79 308 2 075 559 213 080 278 308 284 101 210 193 158 456

U153 4. Fires 950 628 104 597 62 644 93 819 79 537 41 260 12 267 16 498 7 362 417 984 94 773 60 257 148 494 88 532 55 824

U156 5. Drownings 2 162 313 298 211 425 418 314 721 159 308 106 353 55 005 31 652 10 813 1 401 482 181 110 162 423 99 389 60 416 83 938

U155 6. Other unintentional injuries 10 333 941 963 891 998 301 1 342 714 1 238 739 762 974 286 925 164 707 54 235 5 812 487 803 288 649 338 988 142 661 761 600 028

U156 B. Intentional injuries 17 725 711 84 493 380 885 7 438 766 3 588 002 1 168 979 658 340 214 446 56 527 13 590 437 57 627 274 225 765 201 1 169 039 1 034 877

U157 1. Self-inflicted injuries 5 591 032 0 51 805 1 060 732 593 293 422 874 478 167 172 287 43 980 2 823 137 0 91 365 362 937 770 160 801 376

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Female60-69 70-79 80+ Total

31 225 527 27 636 401 11 985 004 181 374 736

630 932 670 008 409 446 14 195 185

350 655 277 190 100 015 4 917 808 93 444 46 555 9 900 621 019 6 802 2 850 1 508 524 550 1 946 1 665 1 117 31 502 1 588 26 0 333 225 1 021 9 0 150 032 2 247 1 150 391 9 791

41 433 7 876 128 1 277 166 64 728 54 883 27 082 1 101 953

462 1 866 347 100 394 0 0 0 39 107 0 19 2 186 0 0 13 599

37 0 78 41 349 425 1 847 254 19 153

7 025 6 516 1 808 126 659 8 594 9 379 2 803 46 701 5 091 5 268 1 175 23 360 5 276 3 396 773 204 316 8 133 6 354 1 527 94 089

74 40 2 6 811 5 780 5 239 1 348 39 827 1 269 461 44 13 770

201 165 25 7 787 794 441 101 25 544

16 7 7 350 158 209 60 3 069 150 144 79 11 686 254 347 158 18 681

37 799 33 204 9 035 122 827 6 973 4 514 1 328 133 041

33 22 0 41 243 3 32 1 27 686

6 857 4 426 1 318 62 959 80 33 10 1 154

64 431 93 949 42 364 518 206 192 493 311 094 272 514 2 105 974 185 024 305 432 261 096 1 961 790

7 363 5 603 11 376 93 200 106 59 42 50 985

0 0 0 1 437 278 0 0 0 99 882 0 0 0 253 915 0 0 0 58 183 0 0 0 176 188 0 0 0 260 572 0 0 0 588 540 3 0 0 4 363 014

0 0 0 1 522 001

3 0 0 1 617 554

0 0 0 1 223 460 87 781 81 724 36 917 1 371 110 7 536 15 813 12 389 424 876

123 325 63 151 934 0 78 60 3 518

77 652 60 575 21 484 770 756 2 468 4 933 2 919 20 026

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28 515 873 25 837 324 11 186 354 144 846 2694 148 195 3 047 667 714 011 15 487 589

70 491 53 991 14 398 267 394 326 228 268 273 55 714 952 514 399 250 394 689 117 628 1 503 679 253 997 236 215 82 029 1 017 029 325 605 272 264 47 399 1 065 798 90 162 97 516 24 600 304 016

1 260 768 790 756 126 400 3 512 838 15 618 16 617 5 023 76 625

503 456 259 765 64 078 2 347 985 245 113 132 860 21 649 1 028 606 65 324 41 073 10 034 238 018

101 608 70 612 14 264 479 229 0 0 0 0

50 687 52 934 16 765 187 288 97 607 79 105 20 007 483 969 67 011 46 461 14 182 716 715

275 270 234 538 79 841 1 305 889 66 778 37 347 10 897 343 028

1 379 730 1 231 556 318 671 5 457 891 161 577 168 977 75 591 1 313 747

3 376 297 2 332 355 1 563 386 39 982 8021 705 937 328 587 77 460 17 525 596

3 867 483 116 2 473 876 27 630 15 443 1 877 3 055 275 49 805 24 804 6 463 883 245 31 323 7 308 1 377 890 573

1 135 648 1 635 194 1 362 988 4 566 010 75 860 115 187 38 517 308 680 6 814 2 957 880 315 764 3 007 652 342 623 976

11 070 4 841 1 187 1 020 494 24 198 6 512 1 106 1 091 909 13 274 7 751 906 1 628 828

147 984 42 116 11 694 906 370 307 21 1 1 772 172 345 308 100 1 050 986

139 229 140 191 58 373 1 869 0476 891 462 3 377 874 678 254 23 651 684

632 587 322 511 99 684 2 074 1991 351 316 888 638 226 425 4 404 1002 040 452 943 800 95 399 6 919 0201 803 367 664 229 97 406 6 759 7191 063 740 558 697 159 340 3 494 6466 569 775 9 631 777 5 041 388 26 652 990

220 055 152 442 53 417 659 714 521 496 851 577 472 425 2 109 445

2 475 025 2 921 651 1 377 236 8 793 3192 642 418 4 377 129 2 220 000 11 180 511

138 831 248 341 161 580 732 551 571 951 1 080 636 756 730 3 177 449

2 269 157 3 907 598 2 090 339 12 638 9041 903 967 3 471 784 1 838 682 8 746 926

125 562 77 810 28 094 2 273 452 239 628 358 005 223 563 1 618 526 521 859 665 014 232 760 2 956 952 55 660 88 966 36 998 318 964

195 841 219 856 51 154 924 247 4 295 6 400 2 466 29 094

266 062 349 792 142 142 1 684 647 425 715 408 046 162 054 2 049 378 311 310 294 864 118 508 1 361 146

0 0 0 0 114 405 113 182 43 546 688 232

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115 542 85 940 68 321 979 6111 947 747 770 559 204 699 9 322 729

297 685 106 496 27 804 1 744 2911 345 892 448 299 71 185 5 546 895

18 829 9 814 2 480 141 992 46 616 16 613 3 648 526 789

238 725 189 336 99 582 1 362 762 5 966 3 183 2 491 1 735 008

41 26 7 8 653 88 16 58 29 308 56 2 13 3 018 0 0 0 29 532 0 0 0 18 284 4 2 10 4 554

54 1 2 3 296 249 23 62 392 444

2 488 1 711 1 366 818 958 90 105 40 94 532

2 897 1 296 932 332 428 636 073 169 430 23 492 2 273 957 90 029 41 616 12 423 1 099 720 5 583 2 557 824 57 791

536 925 122 702 8 723 1 089 841 3 535 2 555 1 523 26 605

2 078 721 1 129 068 389 204 22 333 2831 565 859 867 157 329 672 18 198 009

580 647 257 284 48 237 10 167 775 85 057 31 978 8 635 397 531

254 327 259 540 159 769 1 817 775 39 799 33 504 11 461 532 644 95 923 59 865 17 766 760 831

510 107 224 987 83 803 4 521 453 512 862 261 911 59 531 4 135 273 452 419 236 345 53 293 2 767 895

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GBD 2004: Projected DALYs by age, sex and cause for the year 2030, optimistic scenarioLow income countries (a)

Male FemaleCode Cause Total 0-4 5-14 15-29 30-44 45-59 60-69 70-79 80+ Total 0-4 5-14 15-29 30-44 45-59 60-69U000 All Causes 657 867 503 72 620 853 24 459 394 67 646 189 76 766 872 69 209 244 31 602 321 15 727 910 5 083 921 363 116 704 57 490 752 19 837 975 53 915 102 52 611 612 51 386 375 31 413 433

U001 I.157 210 812 54 611 296 4 743 439 7 034 347 9 741 298 5 441 740 1 866 715 1 066 640 377 477 84 882 952 41 538 909 4 120 207 11 169 982 9 457 039 3 238 704 1 327 144

U002 A. Infectious and parasitic diseases 65 209 179 14 630 391 3 002 965 5 744 929 8 168 906 4 049 809 914 257 423 050 135 963 37 070 272 10 217 380 2 391 426 5 299 342 6 641 193 2 316 656 674 904

U003 1. Tuberculosis 9 743 805 260 895 238 144 1 624 030 2 288 432 1 259 403 303 650 83 456 14 338 6 072 347 254 443 259 394 1 277 236 1 141 310 494 086 179 077

U004 2. STDs excluding HIV 3 756 211 458 247 10 210 555 932 270 569 74 541 31 291 20 479 7 761 1 429 029 364 725 29 732 1 447 274 415 686 41 892 15 570

U005 a. Syphilis 637 018 200 343 859 57 008 37 952 40 628 28 191 16 760 5 959 387 701 143 493 938 55 068 32 146 2 117 7 411

U006 b. Chlamydia 1 319 514 533 2 597 115 297 24 473 599 63 0 0 143 563 461 20 272 953 857 169 969 27 546 3 846

U007 c. Gonorrhoea 1 719 789 253 846 6 751 382 838 196 345 3 026 299 0 0 843 105 218 341 8 522 437 517 210 000 1 996 234

U008 d. Other STDs 79 889 3 525 3 788 11 799 30 287 2 738 3 719 1 801 54 659 2 430 0 832 3 572 10 233 4 079

U009 3. HIV/AIDS 15 064 830 516 886 628 269 1 500 768 3 167 130 1 014 565 144 986 8 645 68 6 981 317 522 233 664 113 1 568 156 4 265 480 913 502 102 194

U010 4. Diarrhoeal diseases 11 520 861 5 138 602 391 668 328 133 419 522 340 783 135 981 84 004 41 204 6 879 898 3 541 208 288 905 243 887 168 992 173 239 100 130

U011 5. Childhood-cluster diseases 4 325 074 2 581 905 52 510 17 521 21 998 10 000 1 746 432 356 2 686 468 1 581 537 34 696 6 731 10 922 3 191 805

U012 a. Pertussis 1 344 281 792 839 4 077 754 0 0 112 0 0 797 782 541 825 4 030 342 303 0 0

U013 b. Poliomyelitis (c) 4 844 1 235 0 759 375 814 0 0 43 3 226 1 073 0 0 254 291 0

U014 c. Diphtheria 25 892 13 800 738 164 32 461 62 0 45 15 303 9 387 1 130 45 25 0 0

U015 d. Measles 2 100 493 1 215 651 42 672 1 392 0 0 0 0 0 1 259 715 812 346 26 767 1 393 272 0 0

U016 e. Tetanus 849 564 558 380 5 023 14 452 21 590 8 724 1 572 432 268 610 442 216 905 2 769 4 951 10 068 2 900 805

U017 6. Meningitis 1 761 926 459 553 163 752 170 268 130 800 111 996 24 250 17 179 5 034 1 082 832 319 552 174 198 87 394 32 756 38 146 13 689

U018 7. Hepatitis B (d) 343 272 28 126 3 166 38 094 86 097 82 622 13 143 8 055 2 651 261 953 21 049 2 211 16 844 13 605 17 572 4 703

U019 Hepatitis C (d) 134 812 11 264 1 323 13 844 33 799 33 149 5 227 3 202 1 050 102 859 8 463 930 6 734 5 257 6 936 1 689

U020 8. Malaria 8 339 170 4 136 610 361 293 175 740 146 679 78 511 15 715 6 340 1 378 4 922 266 2 880 677 256 382 121 506 86 073 50 743 13 226

U021 9. Tropical-cluster diseases 3 381 103 101 790 509 678 867 664 728 574 346 239 45 480 14 489 2 297 2 616 212 67 414 166 091 189 324 149 847 157 009 24 203

U022 a. Trypanosomiasis 555 694 14 664 116 377 103 778 99 554 65 102 3 858 1 523 103 404 958 10 989 42 429 42 223 32 727 20 189 1 433

U023 b. Chagas disease 1 192 0 0 262 153 141 56 36 33 680 0 0 190 67 93 117

U024 c. Schistosomiasis 575 943 34 459 101 129 55 305 111 722 71 017 21 477 5 852 708 401 668 19 764 51 633 23 178 41 515 25 293 9 444

U025 d. Leishmaniasis 352 481 12 606 58 649 86 325 73 942 24 294 5 460 1 754 66 263 095 8 264 25 071 30 379 13 414 7 571 3 485

U026 e. lymphatic filariasis 1 695 942 36 609 227 357 601 163 395 091 138 300 5 873 1 813 337 1 406 541 26 103 42 198 81 154 43 994 87 380 5 737

U027 f. Onchocerciasis 199 852 3 453 6 165 20 833 48 113 47 386 8 756 3 513 1 051 139 270 2 295 4 760 12 200 18 130 16 482 3 988

U028 10. Leprosy 56 015 898 5 990 6 321 10 883 7 205 1 625 1 380 282 34 585 637 5 616 5 138 5 348 3 291 540

U029 11. Dengue 36 007 3 589 15 097 607 923 457 163 120 75 21 031 1 975 11 654 354 452 270 112

U030 12. Japanese encephalitis 73 023 14 352 15 684 5 206 3 036 923 287 358 151 39 998 9 712 17 319 3 067 1 479 617 264

U031 13. Trachoma 437 204 166 219 5 144 44 050 55 902 26 339 14 145 3 648 149 612 210 416 6 429 67 885 93 050 63 539

U032 14. Intestinal nematode infections 875 090 77 451 313 868 42 594 34 126 17 703 4 588 2 031 617 492 977 64 286 247 114 30 253 20 944 12 487 4 119

U033 a. Ascariasis 442 909 53 771 191 963 130 52 3 1 1 49 245 970 44 830 151 754 15 308 2 17

U034 b. Trichuriasis 173 871 22 486 75 093 13 11 6 2 1 0 97 611 18 812 57 426 9 6 4 1

U035 c. Hookworm disease 254 966 28 46 458 42 355 34 026 17 303 4 495 1 920 526 147 112 20 37 786 30 163 20 585 12 479 4 077

U036 Other intestinal infections 3 344 1 166 354 96 36 390 90 110 42 2 284 623 148 66 45 2 25

U037 Other infectious diseases 5 378 891 842 253 296 135 393 428 782 935 615 861 159 795 158 788 55 063 3 304 258 579 654 242 202 289 258 255 506 310 677 151 076

U038 B. Respiratory infections 26 567 307 9 646 272 1 208 506 861 072 1 188 843 1 102 942 874 123 594 530 224 741 15 701 029 6 834 558 1 059 248 548 581 485 659 582 798 555 611

U039 1. Lower respiratory infections 25 834 377 9 513 503 1 085 587 816 655 1 145 002 1 066 746 855 529 582 633 220 274 15 285 929 6 732 952 965 064 510 056 450 024 561 667 541 624

U040 2. Upper respiratory infections 497 326 102 846 36 496 35 296 39 053 31 665 17 819 11 653 4 338 279 167 77 465 31 398 31 856 31 829 19 272 13 618

U041 3. Otitis media 235 604 29 923 86 423 9 121 4 788 4 531 775 243 129 135 933 24 142 62 786 6 670 3 806 1 860 368

U042 C. Maternal conditions 7 152 343 0 0 0 0 0 0 0 0 0 0 255 387 4 878 012 1 983 175 35 769 0

U043 1. Maternal haemorrhage 874 225 0 0 0 0 0 0 0 0 0 0 19 482 890 381 473 9 843 0

U044 2. Maternal sepsis 940 715 0 0 0 0 0 0 0 0 0 0 1 486 676 296 259 793 3 140 0

U045 3. Hypertensive disorders 302 037 0 0 0 0 0 0 0 0 0 0 10 341 191 170 97 814 2 711 0

U046 4. Obstructed labour 971 996 0 0 0 0 0 0 0 0 0 0 0 715 816 253 787 2 393 0

U047 5. Abortion 1 424 831 0 0 0 0 0 0 0 0 0 0 238 825 1 030 615 155 385 6 0

U048 Other maternal conditions 2 638 538 0 0 0 0 0 0 0 0 0 0 4 715 1 781 224 834 923 17 676 0

U049 D. Perinatal conditions (e) 49 601 698 27 452 074 77 0 0 0 0 0 0 27 452 151 22 149 452 95 0 0 0 0

U050 1. Prematurity and low birth weight 15 999 275 8 882 201 0 0 0 0 0 0 0 8 882 201 7 117 075 0 0 0 0 0

U051 2. Birth asphyxia and birth trauma 16 356 524 8 910 722 4 0 0 0 0 0 0 8 910 727 7 445 798 0 0 0 0 0

U052 3. 17 245 899 9 659 151 73 0 0 0 0 0 0 9 659 224 7 586 580 95 0 0 0 0

U053 E. Nutritional deficiencies 8 680 285 2 882 560 531 891 428 346 383 549 288 989 78 334 49 060 16 773 4 659 501 2 337 519 414 052 444 046 347 012 303 481 96 629

U054 1. Protein-energy malnutrition 4 296 914 2 167 576 88 758 35 759 59 112 36 220 3 578 3 282 1 556 2 395 842 1 759 402 76 770 14 991 20 394 21 693 4 068

U055 2. Iodine deficiency 762 160 340 371 77 461 8 28 307 8 8 1 418 192 283 067 60 501 147 131 103 15

U056 3. Vitamin A deficiency 131 064 67 175 8 173 179 100 137 58 45 6 75 874 50 924 3 830 76 248 38 34

U057 4. Iron-deficiency anaemia 3 323 201 285 758 352 791 384 393 304 751 228 369 67 500 35 138 11 488 1 670 188 228 450 267 872 425 945 322 019 271 215 85 631U058 Other nutritional disorders 166 945 21 680 4 708 8 006 19 558 23 955 7 190 10 587 3 722 99 406 15 676 5 078 2 887 4 219 10 432 6 881

Communicable, maternal, perinatal and nutritional conditions

Neonatal infections and other conditions (f)

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U059 II. Noncommunicable diseases 379 764 601 11 528 521 8 856 102 33 397 512 41 748 040 53 854 395 27 777 235 13 787 073 4 415 219 195 364 097 10 595 603 9 036 663 32 208 577 35 766 619 43 336 269 28 202 659

U060 A. Malignant neoplasms 34 398 469 473 498 704 526 1 247 731 2 441 252 5 481 417 3 842 619 2 007 139 649 118 16 847 301 550 771 601 444 1 240 901 3 003 718 5 910 610 3 621 341

U061 1. Mouth and oropharynx cancers 3 328 002 4 722 16 187 116 190 314 926 885 477 587 514 253 915 83 820 2 262 751 15 346 13 203 29 272 110 097 382 596 285 953

U062 2. Oesophagus cancer 2 361 806 1 480 2 858 20 061 152 183 472 463 378 168 191 090 54 366 1 272 670 1 175 1 944 26 601 133 388 397 784 301 716

U063 3. Stomach cancer 2 082 643 1 832 7 322 54 088 179 335 427 832 263 691 144 153 57 329 1 135 583 559 3 189 52 562 183 222 314 477 217 142

U064 4. Colon and rectum cancers 1 475 420 608 8 930 71 955 186 550 268 436 154 912 86 631 40 605 818 627 405 3 061 28 051 158 010 208 079 134 773

U065 5. Liver cancer 2 402 299 25 427 20 086 102 250 311 362 583 010 324 178 151 765 34 095 1 552 173 27 032 14 151 100 348 190 145 251 417 152 123

U066 6. Pancreas cancer 551 984 824 1 975 2 196 41 891 103 355 67 081 34 890 12 651 264 864 63 548 7 883 47 436 106 139 69 291

U067 7. Trachea, bronchus, lung cancers 3 963 716 0 2 0 324 492 1 272 682 999 935 408 001 67 741 3 072 852 0 3 1 139 138 357 452 248 332

U068 8. Melanoma and other skin cancers 237 442 708 1 408 10 621 14 197 48 367 18 015 9 781 3 844 106 939 1 137 2 623 9 265 20 775 44 209 30 172

U069 9. Breast cancer 3 052 412 0 0 0 0 79 15 7 0 102 510 3 861 47 387 748 364 1 275 184 602 743

U070 10. Cervix uteri cancer 3 317 681 0 0 0 0 0 0 0 0 0 33 1 575 416 066 333 921 1 340 280 785 297

U071 11. Corpus uteri cancer 194 764 0 0 0 0 0 0 0 0 0 4 153 5 624 3 917 30 012 66 068 46 730

U072 12. Ovary cancer 877 076 0 0 0 0 0 0 0 0 0 2 004 27 457 85 518 169 271 289 750 175 205

U073 13. Prostate cancer 966 835 581 1 349 1 441 8 163 190 827 315 987 332 448 116 039 966 835 0 0 0 0 0 0

U074 14. Bladder cancer 593 951 1 449 1 872 6 538 21 771 108 778 126 450 93 606 45 034 405 499 1 586 769 4 348 25 524 47 880 48 381

U075 15. Lymphomas, multiple myeloma 2 740 892 91 840 308 915 321 164 340 528 312 799 168 247 94 003 37 294 1 674 791 73 259 194 936 147 404 174 903 199 380 146 828

U076 16. Leukaemia 2 026 756 116 595 187 707 399 325 170 449 127 515 61 404 32 409 13 745 1 109 149 133 426 175 809 217 700 147 483 138 568 58 735

U077 Other malignant neoplasms 4 224 791 227 433 145 915 141 900 375 404 679 796 377 021 174 441 82 555 2 204 466 290 083 152 690 64 579 392 028 491 346 317 919

U078 B. Other neoplasms 1 224 058 48 537 77 154 144 283 116 558 109 970 47 838 30 715 9 632 584 687 55 443 111 713 74 857 150 242 136 482 63 749

U079 C. Diabetes mellitus 9 448 297 22 923 35 731 293 714 977 227 1 925 302 910 522 449 070 154 989 4 769 479 21 384 37 108 180 361 779 118 1 670 218 1 154 174

U080 D. Endocrine disorders 4 257 621 453 098 96 374 297 958 400 155 537 059 199 819 102 985 39 008 2 126 456 288 288 103 873 300 842 367 701 537 510 280 275

U081 E. Neuropsychiatric conditions 102 504 049 2 575 018 4 176 954 21 504 086 11 835 302 5 094 663 1 248 346 962 411 443 910 47 840 690 2 627 674 4 739 548 22 760 518 13 614 756 6 397 538 2 289 503

U082 1. Unipolar depressive disorders 41 595 820 37 1 648 628 5 565 074 5 079 137 2 402 819 484 457 69 720 15 381 15 265 252 22 1 671 080 9 357 848 9 235 475 4 598 529 1 211 917

U083 2. Bipolar disorder 7 720 867 38 228 667 3 329 089 375 661 9 010 1 638 120 0 3 944 224 31 140 213 3 243 322 380 048 10 271 2 532

U084 3. Schizophrenia 9 086 766 198 421 575 3 392 911 458 197 145 601 20 444 8 290 2 641 4 449 858 117 76 856 3 552 480 775 962 176 798 31 794

U085 4. Epilepsy 4 222 091 228 118 516 209 729 751 505 716 259 387 69 702 27 875 7 433 2 344 190 216 769 458 451 626 729 314 817 169 235 54 215

U086 5. Alcohol use disorders 6 805 886 203 147 001 2 785 382 2 451 426 729 489 74 924 11 021 1 959 6 201 405 12 877 48 478 205 567 200 702 109 046 20 467

U087 6. Alzheimer and other dementias 3 803 657 108 505 50 807 56 422 28 245 133 470 222 083 591 711 323 733 1 514 975 100 941 50 121 53 875 32 513 153 348 467 520

U088 7. Parkinson disease 499 488 1 179 438 673 31 682 101 143 52 104 49 966 19 429 256 616 715 459 1 028 27 518 93 911 51 567

U089 8. Multiple sclerosis 703 466 235 31 455 145 988 100 130 18 887 5 359 1 368 472 303 893 319 42 425 194 583 129 485 26 231 4 484

U090 9. Drug use disorders 4 222 236 1 78 845 1 767 913 1 244 387 361 947 13 820 1 991 530 3 469 434 1 37 191 385 529 254 205 71 494 2 959

U091 10. Post-traumatic stress disorder 2 055 778 4 22 015 288 348 167 502 71 498 921 388 215 550 891 2 15 645 804 976 464 880 210 460 5 703

U092 11. Obsessive-compulsive disorder 3 196 040 0 159 092 807 670 300 912 67 940 9 046 1 651 272 1 346 583 0 458 561 687 742 526 701 144 136 26 208

U093 12. Panic disorder 3 907 292 0 63 744 1 199 870 14 920 39 069 3 510 1 534 180 1 322 827 0 65 698 2 397 053 23 473 84 736 8 496

U094 13. Insomnia (primary) 2 363 638 0 16 694 407 975 441 746 202 718 69 196 13 127 3 111 1 154 567 0 25 314 329 384 452 260 253 508 107 976

U095 14. Migraine 3 267 989 37 662 402 806 400 426 103 374 4 644 76 15 1 949 004 99 914 1 381 793 440 265 390 296 6 498 217

U096 15. Mental retardation, lead-caused 3 167 814 1 586 360 3 599 6 044 3 070 883 150 28 4 1 600 137 1 559 019 4 107 2 710 1 054 511 14

Other neuropsychiatric disorders 5 885 220 612 479 385 379 620 552 529 198 546 157 220 915 183 606 68 549 3 166 833 636 946 263 155 477 426 405 367 288 828 293 435

U098 F. Sense organ diseases 60 164 205 129 724 654 700 1 658 138 8 403 363 9 959 492 5 228 735 1 707 722 323 611 28 065 486 101 874 523 739 1 229 464 8 543 961 11 154 029 7 204 847

U099 1. Glaucoma 3 759 727 17 355 52 186 171 524 451 136 553 424 232 894 95 372 27 981 1 601 872 1 788 8 248 148 342 561 731 785 309 411 902

U100 2. Cataracts 12 732 103 8 103 48 788 322 279 1 594 664 2 433 029 974 550 445 732 124 028 5 951 173 3 284 16 187 219 616 1 539 090 2 720 317 1 320 483

U101 3. Refractive errors 18 122 854 101 393 541 590 477 618 1 959 669 2 553 048 2 381 493 670 595 70 340 8 755 747 95 094 493 619 425 154 1 715 380 2 573 318 2 980 839

U102 4. Hearing loss, adult onset 18 777 213 0 0 595 286 3 700 511 3 225 911 1 147 859 298 055 44 208 9 011 830 0 0 322 349 3 942 490 3 390 441 1 561 927

U103 5. Macular degeneration and other (g) 6 772 308 2 873 12 136 91 431 697 383 1 194 080 491 940 197 968 57 054 2 744 864 1 709 5 685 114 002 785 270 1 684 643 929 696

U104 G. Cardiovascular diseases 75 768 150 853 547 404 653 2 213 600 6 949 148 14 459 699 8 956 132 5 428 754 1 897 251 41 162 784 764 102 335 710 1 370 929 3 205 410 8 514 212 8 378 162

U105 1. Rheumatic heart disease 2 469 864 95 954 50 884 281 630 364 639 356 664 137 459 74 449 24 386 1 386 065 93 062 48 494 151 860 179 645 271 067 148 427

U106 2. Hypertensive heart disease 3 401 371 15 604 10 560 63 008 289 666 588 102 370 593 256 857 109 088 1 703 478 15 028 11 038 30 919 141 726 450 061 413 957

U107 3. Ischaemic heart disease 34 950 517 41 475 38 810 493 765 3 212 242 8 415 037 4 828 493 2 679 263 831 124 20 540 209 36 380 14 575 353 444 1 139 744 3 829 617 4 177 207

U108 4. Cerebrovascular disease 21 427 511 133 692 75 900 530 736 1 437 222 3 580 898 2 726 142 1 751 853 582 316 10 818 759 107 505 75 860 328 551 959 966 2 435 500 2 587 817

U109 5. Inflammatory heart diseases (h) 2 965 517 177 697 37 570 305 887 507 987 312 871 193 233 121 856 44 071 1 701 171 148 055 27 650 120 896 209 687 278 945 179 580U110 Other cardiovascular diseases 10 553 371 389 125 190 930 538 575 1 137 392 1 206 126 700 213 544 476 306 267 5 013 103 364 074 158 092 385 258 574 641 1 249 022 871 175

U111 H. Respiratory diseases 35 918 576 921 664 1 356 434 2 273 329 3 798 182 7 501 670 4 480 819 2 019 855 565 582 22 917 534 716 633 1 417 473 1 788 816 1 424 081 3 233 652 2 255 676

U112 1. Chronic obstructive pulmonary disea 20 043 542 12 965 23 020 64 576 2 031 129 5 768 232 3 839 543 1 637 378 433 961 13 810 804 10 887 7 809 42 229 469 328 2 239 481 1 774 765

U113 2. Asthma 10 072 184 589 797 1 177 948 1 862 240 993 031 837 986 190 123 87 967 23 845 5 762 938 406 572 1 305 820 1 341 627 469 658 527 851 150 081

U114 Other respiratory diseases 5 802 850 318 902 155 466 346 513 774 022 895 452 451 153 294 510 107 776 3 343 793 299 174 103 844 404 960 485 095 466 320 330 829

U115 I. Digestive diseases 14 890 397 320 151 312 508 1 226 631 3 015 576 3 242 051 997 232 362 248 102 616 9 579 012 295 141 220 480 948 436 1 181 846 1 500 678 664 249

U116 1. Peptic ulcer disease 2 667 740 10 471 64 566 207 635 667 691 712 105 180 322 80 584 22 812 1 946 186 22 606 9 449 78 252 179 542 229 039 104 387

U117 2. Cirrhosis of the liver 4 376 813 56 704 86 271 204 843 764 277 1 359 428 441 594 146 078 30 389 3 089 586 62 196 46 667 161 820 217 776 422 633 217 521

U118 3. Appendicitis 185 991 298 20 362 29 924 24 281 33 822 11 976 5 838 1 986 128 487 266 8 684 9 892 5 938 11 981 10 816

U119 Other digestive diseases 7 659 853 252 678 141 309 784 229 1 559 327 1 136 696 363 340 129 748 47 429 4 414 754 210 073 155 680 698 473 778 590 837 025 331 525

U120 J. Genitourinary diseases 8 345 642 172 652 138 073 467 637 1 005 434 2 686 404 696 866 375 807 140 105 5 682 978 162 365 84 322 262 471 501 626 803 914 444 487

U121 1. Nephritis and nephrosis 5 437 847 144 712 125 895 372 836 865 731 956 468 478 342 264 180 99 089 3 307 254 140 656 77 941 175 317 354 413 647 986 379 388

U122 2. Benign prostatic hypertrophy 1 860 078 0 0 0 14 697 1 593 014 150 146 75 257 26 965 1 860 078 0 0 0 0 0 0

U123 Other genitourinary system diseases 1 047 717 27 940 12 178 94 800 125 007 136 921 68 378 36 370 14 051 515 646 21 709 6 381 87 155 147 213 155 928 65 100

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U124 K. Skin diseases 2 864 799 182 906 204 905 379 896 397 085 235 682 83 045 43 566 19 263 1 546 349 111 673 109 332 283 024 293 177 274 118 113 433

U125 L. Musculoskeletal diseases 14 587 924 75 245 338 878 1 091 320 2 126 354 1 926 690 600 014 213 370 54 973 6 426 843 53 640 409 348 1 247 320 2 432 092 2 446 054 1 080 237

U126 1. Rheumatoid arthritis 2 248 642 7 669 58 430 156 051 196 493 187 652 67 141 26 200 7 374 707 010 8 995 117 695 306 450 449 591 436 232 148 018

U127 2. Osteoarthritis 7 561 146 34 2 069 345 502 990 699 1 089 984 365 562 110 185 19 333 2 923 367 34 5 010 557 960 1 511 538 1 593 280 738 063

U128 3. Gout 1 166 664 2 186 64 759 590 242 329 075 44 764 10 538 2 174 1 041 739 1 65 13 437 59 867 33 685 11 301

U129 4. Low back pain 1 475 350 49 359 158 804 192 298 180 247 137 354 30 573 9 821 2 407 760 864 26 772 195 559 134 845 188 852 123 866 31 662

U130 Other musculoskeletal disorders 2 136 121 18 180 119 388 332 711 168 674 182 624 91 974 56 626 23 685 993 862 17 838 91 019 234 628 222 244 258 991 151 193

U131 M. Congenital anomalies 10 302 290 5 124 012 77 321 152 607 34 348 16 940 3 940 2 507 1 110 5 412 785 4 676 077 71 793 88 919 24 916 19 591 4 694

U132 1. Abdominal wall defect 62 415 34 219 18 13 10 2 0 0 6 34 268 28 100 25 11 2 2 0

U133 2. Anencephaly 215 118 115 117 37 31 8 4 1 0 12 115 209 99 746 82 36 7 11 27

U134 3. Anorectal atresia 26 839 14 095 95 295 18 6 3 2 1 14 513 12 076 65 166 8 6 2

U135 4. Cleft lip 57 734 30 354 1 1 0 0 0 0 0 30 356 27 376 1 0 0 0 0

U136 5. Cleft palate 92 243 47 000 19 95 132 0 0 0 0 47 247 44 761 5 2 0 229 0

U137 6. Oesophageal atresia 9 104 5 049 88 218 46 34 8 4 1 5 447 3 303 144 132 28 31 11

U138 7. Renal agenesis 17 532 9 581 103 49 41 370 223 3 1 10 372 6 917 120 29 23 27 37

U139 8. Down syndrome 2 599 680 1 333 075 15 028 42 647 559 1 325 198 0 57 1 392 889 1 165 815 12 112 24 492 1 828 2 544 0

U140 9. Congenital heart anomalies 4 906 145 2 368 707 40 308 91 041 19 399 5 979 1 476 1 402 676 2 528 987 2 267 427 37 642 50 031 11 351 7 195 1 992

U141 10. Spina bifida 709 107 355 900 4 607 1 932 636 434 151 3 57 363 719 341 374 1 195 1 307 830 456 2

U142 Other Congenital anomalies 1 606 371 810 916 17 016 16 284 13 499 8 788 1 880 1 093 300 869 777 679 181 20 403 12 711 10 839 9 090 2 624

U143 N. Oral conditions 5 090 126 175 546 277 891 446 581 248 057 677 356 481 307 80 924 14 052 2 401 714 170 537 270 780 431 719 243 977 737 662 647 831

U144 1. Dental caries 2 863 450 168 026 276 694 390 718 158 350 264 098 105 289 38 684 11 248 1 413 107 162 884 267 935 373 546 153 732 281 305 137 015

U145 2. Periodontal disease 272 172 0 0 37 495 68 999 20 759 4 862 1 790 605 134 510 0 738 36 069 68 763 22 047 6 485

U146 3. Edentulism 1 867 715 0 0 11 302 7 630 387 945 369 411 38 574 1 594 816 457 0 0 11 857 8 338 425 183 501 016

U147 Other oral diseases 86 788 7 520 1 198 7 067 13 078 4 554 1 744 1 875 604 37 640 7 653 2 107 10 246 13 144 9 127 3 316

U148 III.Injuries 120 892 090 6 481 036 10 859 852 27 214 331 25 277 533 9 913 110 1 958 372 874 197 291 224 82 869 654 5 356 239 6 681 104 10 536 543 7 387 954 4 811 401 1 883 630

U149 A. Unintentional injuries 93 354 937 6 143 503 9 655 408 18 446 727 18 024 199 7 785 658 1 578 518 733 734 238 348 62 606 095 5 055 258 6 083 744 7 690 937 5 459 691 3 625 776 1 618 916

U150 1. Road traffic accidents 50 597 369 2 126 593 5 540 632 13 391 450 10 795 216 4 429 837 714 090 279 713 76 687 37 354 219 1 848 972 3 613 660 3 633 600 2 149 915 1 436 098 350 035

U151 2. Poisonings 3 484 705 309 158 172 806 274 024 697 252 512 915 108 341 27 593 9 066 2 111 155 153 344 102 253 204 523 249 843 249 343 324 632

U152 3. Falls 6 000 551 447 421 777 330 547 270 808 627 490 840 211 413 189 929 80 175 3 553 004 343 878 520 506 358 612 328 638 295 330 227 006

U153 4. Fires 6 832 471 842 820 486 676 355 736 753 081 266 636 52 738 26 346 8 523 2 792 557 854 915 389 366 1 128 891 969 777 413 783 157 235

U154 5. Drownings 4 662 131 568 414 523 946 636 915 1 146 422 451 591 58 595 25 214 9 302 3 420 399 375 560 194 385 265 158 159 933 129 392 70 748

U155 6. Other unintentional injuries 21 777 710 1 849 098 2 154 018 3 241 331 3 823 601 1 633 840 433 340 184 939 54 594 13 374 761 1 478 588 1 263 575 2 100 153 1 601 586 1 101 830 489 260

U156 B. Intentional injuries 27 537 154 337 533 1 204 444 8 767 603 7 253 334 2 127 452 379 854 140 463 52 876 20 263 559 300 981 597 360 2 845 606 1 928 263 1 185 625 264 714

U157 1. Self-inflicted injuries 10 220 291 0 189 599 2 992 942 2 263 260 784 759 160 240 72 303 22 510 6 485 614 0 176 360 1 750 044 994 098 620 572 109 545

U158 2. Violence 12 211 836 283 033 702 728 3 959 394 3 461 301 1 027 719 159 902 54 020 24 653 9 672 749 241 179 195 526 900 272 642 739 393 073 118 030

U159 3. War and civil conflict 4 885 502 53 797 296 041 1 746 863 1 466 662 297 346 49 758 10 021 4 088 3 924 575 55 744 221 552 187 498 285 062 162 570 32 534

U160 Other intentional injuries 219 526 703 16 076 68 404 62 111 17 628 9 954 4 119 1 625 180 621 4 058 3 921 7 793 6 364 9 410 4 606

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Female70-79 80+ Total

21 528 236 6 567 315 294 750 800

1 114 870 361 004 72 327 860

469 159 128 847 28 138 908 57 615 8 297 3 671 458 9 904 2 399 2 327 182 6 763 1 381 249 316

0 0 1 175 951 74 0 876 684

3 066 1 018 25 230 47 657 178 8 083 513 84 401 40 202 4 640 963

471 254 1 638 606 0 0 546 500 0 0 1 618 0 1 10 589 0 0 840 778

471 253 239 122 10 542 2 817 679 094 3 862 1 473 81 319 1 494 449 31 953 6 954 1 343 3 416 904 9 595 1 408 764 890

701 44 150 735 37 8 511

3 159 289 174 275 1 157 46 89 386 2 415 421 289 401 2 127 600 60 581

666 195 21 430 105 54 14 976 403 165 33 024

45 007 11 056 287 592 2 306 603 382 112

12 0 196 938 1 0 76 260

2 178 568 107 855 116 35 1 059

188 260 58 000 2 074 633 585 528 214 294 10 866 278 576 006 211 054 10 548 448

9 522 3 199 218 159 0 40 99 671 0 0 7 152 343 0 0 874 225 0 0 940 715 0 0 302 037 0 0 971 996 0 0 1 424 831 0 0 2 638 538 0 0 22 149 547

0 0 7 117 075

0 0 7 445 798

0 0 7 586 675 60 183 17 863 4 020 784 2 932 823 1 901 073

4 1 343 969 35 5 55 190

40 438 11 443 1 653 013 16 774 5 591 67 539

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19 365 515 5 888 598 184 400 5041 990 094 632 288 17 551 168

166 061 62 723 1 065 251 169 099 57 428 1 089 136 124 642 51 267 947 060 84 345 40 070 656 792 95 363 19 547 850 126 42 029 13 730 287 119

126 988 18 949 890 863 18 375 3 946 130 502

284 584 89 678 3 052 310 367 555 72 954 3 317 681 28 634 9 626 194 764

100 264 27 607 877 076 0 0 0

41 984 17 980 188 452 99 170 30 221 1 066 101 32 243 13 643 917 607

208 759 102 920 2 020 325 34 096 12 789 639 371

681 147 155 309 4 678 818 179 381 73 294 2 131 164

1 508 866 724 955 54 663 358 210 436 45 262 26 330 568

173 53 3 776 643 18 283 4 618 4 636 908 30 241 7 443 1 877 900 6 534 809 604 480

876 901 553 461 2 288 681 52 814 14 861 242 873 1 536 509 399 573

966 456 752 802 2 664 558 1 504 887 5 127 983 1 849 457 4 526 483 2 584 465

35 334 5 294 1 209 071 3 0 2 318 984

209 54 1 567 677 263 119 90 111 2 718 388

2 810 879 529 925 32 098 720 189 199 51 334 2 157 855 760 454 201 498 6 780 930 986 007 97 697 9 367 107 476 634 71 541 9 765 383 398 586 107 854 4 027 444

9 093 944 2 942 897 34 605 365 146 088 45 156 1 083 799 452 160 183 004 1 697 894

3 788 278 1 071 063 14 410 3083 099 133 1 014 420 10 608 752

221 689 77 845 1 264 3461 386 596 551 410 5 540 2681 700 136 464 574 13 001 0421 342 917 345 322 6 232 738

84 638 22 999 4 309 246 272 581 96 254 2 459 057 401 606 98 949 5 311 385 77 294 20 985 721 554

133 248 25 367 1 287 227 7 584 2 344 57 504

183 480 50 253 3 245 099 308 605 94 874 2 662 665 271 963 82 930 2 130 593

0 0 0 36 642 11 945 532 072

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102 713 30 980 1 318 450 389 826 102 565 8 161 082 61 612 13 038 1 541 632

199 153 32 742 4 637 779 5 377 1 191 124 925

10 820 2 110 714 486 112 863 53 484 1 142 259

2 566 949 4 889 505 7 0 28 147 0 0 99 909 2 1 12 326 0 0 27 378 0 0 44 996 6 2 3 657 4 1 7 160 0 0 1 206 791

1 072 449 2 377 159 172 51 345 388

1 302 444 736 594 161 656 24 250 2 688 412 57 887 16 040 1 450 344 2 781 778 137 662

98 425 6 441 1 051 258 2 563 991 49 148

1 047 852 317 713 38 022 436 926 118 288 400 30 748 841

167 296 43 575 13 243 150 69 569 20 044 1 373 550

285 989 87 588 2 447 547 95 841 30 105 4 039 914 35 463 11 092 1 241 731

271 961 95 996 8 402 949 121 733 29 313 7 273 595 65 117 18 942 3 734 677

43 442 4 825 2 539 086 11 128 4 838 960 926 2 046 708 38 906