www.npca.org.uk [email protected] npca data collection on men undergoing radical surgery for...
TRANSCRIPT
www.npca.org.uk [email protected]
NPCA data collection on men undergoing radical surgery for
prostate cancer
Paul Cathcart, NPCA Urology Project CoordinatorSenior Lecturer in Genitourinary Oncology
Consultant Urological Surgeon, UCL & Barts
www.npca.org.uk [email protected]
www.npca.org.uk [email protected]
The classic patient presenting in the clinic
• 62 year old chap• Well man clinic – offered a
PSA test• Often asymptomatic • Returns mildly elevated – 5.3• Referred to his local
urologist
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Patient assigned a Gleason grade for his tumour and a clinical stage
• Gleason score 6-10 • (3+3, 3+4, 4+3, 4+4, 4+5, 5+4, 5+5)
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www.npca.org.uk [email protected]
Data Items
• Data item 1 – organisation site code CR1450 – The hospital identifier code
• Data item 2 - consultant code (treatment) CR0660– Code of the consultant (derived from GMC code)
that is responsible for the treatment of the patient• No provision in COSD at present to document the
surgeon who performs the procedure
– NPCA will report surgeon level data on the basis of CR0660
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Data Items
• Type of radical prostatectomy– Open
– Robotic
– Laparoscopic
– Not known
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Data Items• Procedure nerve sparing
– (bilateral, unilateral, none)
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Data Items
• T category (pathological)
• N category (pathological)– Presence of tumour within regional
Lymph nodal tissue
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Data Items• Clinical stage differs from pathological stage• Up to 1/3 of men may be upstaged to T3
disease after surgery
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Data Items• Organ confined (Yes/No)
– Aids completeness of staging – T2 – organ confined– T3 – locally advanced
• Seminal vesicle invasion
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Data Items
• Radical prostatectomy margin status– Negative margins– Positive margins less than 3mm– Positive margins greater than or equal to 3 mm– Positive margin, length unknown
Sooriakumaran P, Ploumidis A, Nyberg T, Olsson M, Akre O, Haendler L, Egevad L, Nilsson A, Carlsson S, Jonsson M, Adding C, Hosseini A, Steineck G, Wiklund P. The impact of length and location of positive margins in predicting biochemical recurrence after robotic-assisted radical prostatectomy with a minimum follow-up time of five years. BJU Int. 2013 Oct 4.
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Data Items
• Lymphadenectomy (Yes/No)
• Change to data item– Used to have number of positive nodes and
number of nodes removed
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Rationale for change in data item
• 174 patients who underwent PLND at two different hospitals• PLND was performed according to a standardized template • Mean number of reported lymph nodes was 16 at hospital A
versus 28 at hospital B• Overall survival (OS), disease-specific survival (DSS) and
recurrence-free survival (RFS) were the same
• Pathological reporting markedly influences nodal yield• The data item was therefore not felt reliable for national use
Mertens LS, Meijer RP, van Werkhoven E, Bex A, van der Poel HG, van Rhijn BW, Meinhardt W, Horenblas S Differences in histopathological evaluation of standard lymph node dissections result in differences in nodal count but not in survival.World J Urol. 2013 Oct;31(5):1297-302
