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Preliminary Program Application for CME credits submitted Workshop Workshop on Oral, Gastrointestinal and Pulmonary GvHD November 17 – 18, 2017 University Hospital Regensburg Regensburg, Germany

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Page 1: Workshop on Oral, Gastrointestinal and Pulmonary GvHD€¦ · SCT-OUTPATIENT CLINIC St . Anna Children‘s Hospital Kinderspitalgasse 6 1090 Wien-Alsergrund Austria anita .lawitschka@stanna

Preliminary Program

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Application for CME credits submitted

Organized by:

FALK FOUNDATION e.V.Leinenweberstr. 579108 FreiburgGermany

Congress DepartmentTelephone: +49 (0) 761/15 14-125Telefax: +49 (0) 761/15 14-359E-Mail: symposia@falk-foundation-symposia.orgwww.falk-foundation-symposia.org

Workshop

Workshop on Oral, Gastrointestinal and Pulmonary GvHD

November 17 – 18, 2017University Hospital RegensburgRegensburg, Germany

Organized by:

FALK FOUNDATION e.V.Leinenweberstr. 579108 FreiburgGermany

Telephone: +49 (0) 761/15 14-125 Telefax: +49 (0) 761/15 14-359 E-Mail: [email protected] www.falk-foundation-symposia.org

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Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4

Scientific Program . . . . . . . . . . . . . . . . . . . . . . . . . 6

List of Speakers . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12

CME credits for the Workshop have been applied for at the European Union of Medical Specialists (UEMS) – European Board of Gastroenterology (EBG) .

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Preface

Dear colleagues,

We are pleased to invite you to the Workshop on oral, gastrointestinal and pulmonary GvHD 2017 held in Regensburg . Acute and chronic GvHD continues to be associated with significant morbidity and mortality representing an ongoing challenge in clinical care . Recently, new insights in the pathophysiology of microbial changes associated with different organ GvHD (oral mucosa, gastrointestinal tract and lung) and their impact on immunoregulation have been achieved, their translation into clinical success remains challenging .

The workshop on oral, gastrointestinal & pulmonary GvHD will provide a comprehensive overview on pathophysiology including microbiological changes, and will provide an update on diagnosis, immunosuppressive and supportive treatment of the latter organ manifestations .

The workshop is supported by the Falk Foundation e .V .

E . Holler, M . Edinger, W . Herr, M . Evert, D . Weber, A . Gessner, D . Wolff (Regensburg, Germany)H . Greinix (Graz, Austria), A . Lawitschka (Vienna, Austria), J . Halter (Basel, Switzerland)G .C . Hildebrandt (Lexington, USA), S .Z . Pavletic (Bethesda, USA)

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Workshop

Workshop on Oral, Gastrointestinal and Pulmonary GvHD

November 17 – 18, 2017University Hospital RegensburgRegensburg, Germany

Start of Registration:Friday, November 17, 201711 .00 – 18 .30 hat the congress offi ce

Congress Venue:University Hospital Regensburg-Großer Hörsaal-Franz-Josef-Strauß-Allee 1193053 RegensburgGermany

The Workshop is organized by Falk Foundation e.V.

Scientifi c Organization:Prof . Dr . Daniel WolffDepartment of Hematology and OncologyUniversity Hospital RegensburgFranz-Josef Strauss-Allee 1193053 Regensburg, GermanyTel: +49 (0)941-944-5531Fax: +49 (0)941-944-5543E-Mail: daniel .wolff@ukr .de

Scientifi c Co-Organization:H . Greinix, Graz (Austria)J . Halter, Basel (Switzerland)W . Herr, Regensburg (Germany)G .C . Hildebrandt, Lexington (USA)E . Holler, Regensburg (Germany)S .Z . Pavletic, Bethesda (USA)

Offi cial Language:English

Publication Date of the Final Program: November 2017

The fi nal program will be available on the homepage www .falk-foundation-symposia .org one week before .

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Friday, November 17, 2017

12.45 Welcome W . Herr, Regensburg

Session I Pathophysiology of acute and chronic GvHD I

Chair: G .R . Hill, Brisbane; P . Reddy, Ann Arbor

13.00 Role of APC’s in GvHD G .R . Hill, Brisbane

13.30 Effector T cell programs in GvHD R . Chakraverty, London

14.00 Role of innate lymphoid cells M .-C . Brueggen, Zurich

14.20 Role of regulatory T cells M . Edinger, Regensburg

14.40 Coffee break

Session II Pathophysiology of acute and chronic GvHD II

Chair: R . Chakraverty, London; M . Edinger, Regensburg

15.00 Role of B cells T . Winkler, Erlangen

15.20 Innate immunity R . Zeiser, Freiburg

15.40 Role of antimicrobial peptides and Paneth cells J .L .M . Ferrara, New York

16.00 Pathophysiology of intestinal tolerance P . Reddy, Ann Arbor

16.30 Coffee break

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Friday, November 17, 2017

Session III Lung GvHD

Chair: A . Lawitschka, Vienna; H . Greinix, Graz

17.00 Pathophysiology of lung GvHD G .C . Hildebrandt, Lexington

17.30 Diagnosis of lung GvHD J . Halter, Basel

18.00 Treatment of lung GvHD S .Z . Pavletic, Bethesda

18.30 End of afternoon session

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Saturday, November 18, 2017

Session IV Oral GvHD

Chair: S . Elad, Rochester; D . Wolff, Regensburg

9.00 Microbiom in oral GvHD M . Mravak-Stipetic, Zagreb

9.20 Immunosuppressive treatment of oral GvHD S . Elad, Rochester

10.00 Supportive treatment of oral GvHD E .M . Wagner, Mainz

10.20 Coffee break

Session V GI-GvHD

Chair: A . Gerbitz, Berlin; M .R .M . van den Brink, New York

10.50 Impact of microbiota in experimental GI-GvHD M . van den Brink, New York

11.20 Pathophysiology of microbial changes in clinical D . Weber, GI-GvHD Regensburg

11.50 Microbiota transfer as treatment of GvHD C . Högenauer, Graz

12.10 Diagnosis and treatment of gastrointestinal GvHD E . Holler, Regensburg

12.30 Panel Discussion: R . Chakraverty, London; H . Greinix, Graz; G .R . Hill, Brisbane; C . Högenauer, Graz; E . Holler, Regensburg; P . Reddy, Ann Arbor; R .M . van den Brink, New York

12.50 Summary and closing remarks E . Holler, Regensburg

13.00 Lunch

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List of Speakers, Moderators and Scientific Organizers

Dr. Marie-Charlotte BrueggenDepartment of DermatologyUniversity Hospital ZurichGloriastrasse 318091 ZürichSwitzerlandmarie-charlotte .brueggen@usz .ch

Dr. Ronjon ChakravertyRoyal Free Hampstead National Health Service (NHS) TrustLondonGreat Britainr .chakraverty@ucl .ac .uk

Prof. Dr. Matthias EdingerKlinik für Innere Medizin IIIUniversitätsklinikum RegensburgFranz-Josef-Strauß-Allee 1193053 RegensburgGermanymatthias .edinger@ukr .de

Sharon Elad, M.D.Professor of MedicineDivision of Oral MedicineEastman Institute for Oral HealthUniversity of Rochester Medical Center625 Elmwood Ave .Rochester, NY 14620USAselad@urmc .rochester .edu

James L.M. Ferrara, M.D.Professor of MedicineHematologic MalignanciesTranslational Research CenterThe Tisch Cancer InstituteDivision of Hematology / Medical OncologyHess Center for Science and Medicine1470 Madison Avenue, 6th FloorNew York, NY 10029USAjames .ferrara@mssm .edu

Prof. Dr. Armin GerbitzAllogeneic Stem Cell TransplantationDep . of Hematology/OncologyCharité CVK I Mittelallee 1113353 BerlinGermanyarmin .gerbitz@charite .de

Prof. Dr. Hildegard GreinixKlinische Abteilung für HämatologieMedizinische Universität GrazLKH-Univ . Klinikum GrazAuenbruggerplatz 38 8036 GrazAustriahildegard .greinix@klinikum-graz .at

PD Dr. Jörg HalterHematologyDepartment of MedicineKantonspital BaselPetersgraben 44031 BaselSwitzerlandjoerg .halter@usb .ch

Prof. Dr. Wolfgang HerrKlinik für Innere Medizin IIIUniversitätsklinikum RegensburgFranz-Josef-Strauß-Allee 1193053 RegensburgGermanywolfgang .herr@ukr .de

Gerhard C. Hildebrandt, M.D.Professor of MedicineDivision of Hematology &Blood and Marrow TransplantationUniversity of Kentucky800 Rose StreetLexington KY 40536USAgerhard .hildebrandt@uky .edu

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Prof. Dr. Geoffrey R. HillBone Marrow Transplantation LaboratoryQIMR Berghofer Medical Research Institute300 Herston RdBrisbane, QLD 4006Australiageoff .hill@qimrberghofer .edu .au

Prof. Dr. Christoph Högenauer Division of Gastroenterology and HepatologyDepartment of Internal MedicineMedical University of GrazAuenbruggerplatz 158036 GrazAustriachristoph .hoegenauer@medunigraz .at

Prof. Dr. Ernst HollerKlinik für Innere Medizin IIIUniversitätsklinikum RegensburgFranz-Josef-Strauß-Allee 1193053 RegensburgGermanyernst .holler@ukr .de

Dr. Anita LawitschkaSCT-OUTPATIENT CLINICSt . Anna Children‘s HospitalKinderspitalgasse 6 1090 Wien-AlsergrundAustriaanita .lawitschka@stanna .at

Prof. Dr. Marinka Mravak-Stipetic Clinical Department of Oral MedicineUniversity Hospital Centre Zagreb University of ZagrebGunduliceva 510000 ZagrebCroatiammstipetic@gmail .com

Steven Z. Pavletic, M.D.Head of GvHD and Autoimmunity UnitExperimental Transplantation and Immunology BranchNational Cancer Institute10 Center DriveBethesda, MD 20892-1203USApavletis@mail .nih .gov

Pavan Reddy, Ph.D.Division of Hematology/OncologyDepartment of Internal MedicineUniversity of Michigan Comprehensive Cancer CenterAnn Arbor, MI 49109USAreddypr@umich .edu

Marcel R. M. van den Brink, M.D., Ph.D.Professor of Medicine and ImmunologyDivision of Hematologic OncologyWeill Cornell Medical College1275 York Avenue, Box 111New York, NY 10065USAmuggeoc@mskcc .org

PD Dr. Eva Maria WagnerIII . Medizinische KlinikUniversitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr . 155131 Mainz Germanyeva .wagner@unimedizin-mainz .de

Dr. Daniela WeberKlinik für Innere Medizin IIIUniversitätsklinikum RegensburgFranz-Josef-Strauß-Allee 1193053 RegensburgGermanydaniela .weber@ukr .de

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Prof. Dr. Thomas WinklerSektion HämatopoeseLehrstuhl GenetikNikolaus-Fiebiger-Zentrum Molekulare MedizinGlueckstrasse 691054 ErlangenGermanythomas .winkler@fau .de

Prof. Dr. Daniel WolffKlinik für Innere Medizin IIIUniversitätsklinikum RegensburgFranz-Josef-Strauß-Allee 1193053 RegensburgGermanydaniel .wolff@ukr .de

Prof. Dr. Robert ZeiserKlinik für Innere Medizin ISchwerpunkt Hämatologie, Onkologieund StammzelltransplantationUniversitätsklinikum FreiburgHugstetter Str . 5579106 FreiburgGermanyrobert .zeiser@uniklinik-freiburg .de

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General InformationPrior to the opening of the Workshop in Regensburg

Falk Foundation e .V . Telephone: +49 (0)0761/1514-125Congress Department Telefax: +49 (0)761/1514-359Leinenweberstr . 5 E-mail: symposia@falk-foundation-symposia .org79108 FreiburgGermany

Congress Office and RegistrationDuring the Workshop in Regensburg

Congress Office Telephone: +49 (0)175/7795327

Opening Hours:Friday, November 17, 2017 11 .00 – 18 .30 hSaturday, November 18, 2017 8 .00 – 14 .00 h

University Hospital RegensburgFranz-Josef-Strauss-Allee 1193053 RegensburgGermany

Congress FeesThe participation at the Workshops is free of charge . Please be aware that the number of participants is limited . Registration is mandatory.

Refreshments during the coffee breaks and lunch on November 17 – 18 and a copy of the abstract volume of the Workshop are also free of charge .

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RegistrationCongress registrations must reach the Falk Foundation e .V . by October 15, 2017 at the latest.

After receipt of registration form, each participant will be provided with confirmation of his registration . On presentation of this confirmation at the congress office in Regensburg participants will receive the congress folder containing name badge, final program and the abstract volume .

All participants will receive a written confirmation of attendance and CME credits at the meeting .

Admission to Scientific EventsFor admission to scientific program your name badge should be clearly visible .

Hotel Accommodation If you would like to do a hotel reservation, please contact:

Tourist-Information Altes RathausRathausplatz 493047 RegensburgGermany Tel: +49 (0)941/507-4410Tel: +49 (0)941/507-4418E-Mail: tourismus@regensburg .dewww .tourismus .regensburg .de

Airport International Franz-Josef-Strauß-Airport Munich

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Directions to University Hospital Regensburg

Main Entrance

Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg

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Preliminary Program

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Application for CME credits submitted

Organized by:

FALK FOUNDATION e.V.Leinenweberstr. 579108 FreiburgGermany

Congress DepartmentTelephone: +49 (0) 761/15 14-125Telefax: +49 (0) 761/15 14-359E-Mail: symposia@falk-foundation-symposia.orgwww.falk-foundation-symposia.org

Workshop

Workshop on Oral, Gastrointestinal and Pulmonary GvHD

November 17 – 18, 2017University Hospital RegensburgRegensburg, Germany

Organized by:

FALK FOUNDATION e.V.Leinenweberstr. 579108 FreiburgGermany

Telephone: +49 (0) 761/15 14-125 Telefax: +49 (0) 761/15 14-359 E-Mail: [email protected] www.falk-foundation-symposia.org

Falk

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Preliminary Program

VP

WSR

EG17

E 1-

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016

/1.0

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Stü

Application for CME credits submitted

Organized by:

FALK FOUNDATION e.V.Leinenweberstr. 579108 FreiburgGermany

Congress DepartmentTelephone: +49 (0) 761/15 14-125Telefax: +49 (0) 761/15 14-359E-Mail: symposia@falk-foundation-symposia.orgwww.falk-foundation-symposia.org

Workshop

Workshop on Oral, Gastrointestinal and Pulmonary GvHD

November 17 – 18, 2017University Hospital RegensburgRegensburg, Germany

Organized by:

FALK FOUNDATION e.V.Leinenweberstr. 579108 FreiburgGermany

Telephone: +49 (0) 761/15 14-125 Telefax: +49 (0) 761/15 14-359 E-Mail: [email protected] www.falk-foundation-symposia.org

Falk

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REGISTRATION CARD

WorkshopNovember 17 – 18, 2017Regensburg, Germany

Reg

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Dead

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Novem

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Scientific program of the W

orkshop ______

***

Day ticket (please insert date: _________________)

______

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