within our grasp
DESCRIPTION
Brochure for Mark Roth lectureTRANSCRIPT
WITHIN
OUR
GRASP
WITHIN OUR GRASP Speaker _ 01:32
Mark Roth's research
awakened an unusual notion
from the annals of science:
reversible body metabolic
hibernation. Yes, indeed putting
living organisms into suspended
animation and back safely.”
He’d had papers published in
the most prestigious scientific
and medical journals in the
world, but Ripley’s Believe It
or Not!, For his work making
suspended animation possible
in human beings? That was an
honor. That was science.”
This MacArthur “genius” grant
winner may spur the next big
leap for lifesaving medical
systems with techniques that
buy time for critically ill trauma
patients -- people in desperate
need of organ transplants, for
example whether in emergency
rooms or on battlefields.”
_Ted.com
_Peter Ward
_Esquire Magazine
“
“
“
SPEAKER Mark Roth
WITHIN OUR GRASP Speaker _ 02:32
As a cell biologist in cancer research, Mark Roth studies genes, chromosomes and autoimmune disease. But he’s best known for his research into suspended animation. Already, Roth has managed a world first
putting a vertebrate a zebrafish embryo into an oxygen deprived state for several hours, then restoring that to completely normal development. He’s been able to reduce the core temperature of mice to 10 degrees Celsius, and then revive them, with no adverse effects.
WITHIN OUR GRASP What is_ 03:32
WITHIN OUR GRASP What is_ 04:32
Certain animals can be found in nature that have the ability to become just a little immortal. They use a process of suspended animation to do so. This is the process where animals deanimate themselves appear dead.
Their pulse slows down to a stop, their breathing decreases and metabolic rate drops. After being in this state for a period of time they later wake up without harm.
Breathing decreases and metabolic rate drops. After being in this state for a period of time they later wake up without harm.
WHAT IS Suspended Animation
IMMO
RTAL
ITY
WITHIN OUR GRASP Immortal_ 07:32
IMMORTAL Species that deanimate
Certain animals can be found in nature that have the ability to become just a little immortal. They use a process of suspended animation to do so. This is the process where animals deanimate themselves appear dead.
Putting a vertebrate a zebrafish embryo into an oxygen deprived state for several hours, then restoring that to completely normal development. He’s been able to reduce the core temperature of mice to 10 degrees Celsius, and then revive them, with no adverse effects.
Can be found in nature that have the ability to become just a little immortal. They use a process of suspended animation to do so. This is the process where animals deanimate themselves appear dead.
WITHIN OUR GRASP Immortal_ 08:32
Plant Seeds
Have the ability to be frozen and kept in a state
of deanimation many years. When ready to be
used plant seeds can be thawed and planted.
Bacterial Spores
remarkable species. Bacterial spores have
existed far longer than humans and have been
able to do so because they have the ability to
maintain for as long as 250 million years.
Female Eggs The females eggs are a example of how human
bodies are cable of the state of suspended
animation. In the ovaries eggs can survive for50
years.
Sea Monkeys
Can sustain themselves in a state of
deanimation for an indefinite period of time.
Waiting for water to reanimate.
LIST OF SPECIES
01
02
04
03
Deanimation 50 years
Deanimation 250 million
Life Span
Life Span
WITHIN OUR GRASP Immortal_ 09:32
Bacterial Spores
Have the ability to maintain a state of deanimation for up 250 million years.
Female Eggs
While in the ovaries eggs can survive for up to 50 years or until ready to cycle.
Deanimation Infinite
Deanimation Varies
Life Span
Life Span
WITHIN OUR GRASP Immortal_ 10:32
Plant Seeds
Have the ability to be frozen and kept in a state of deanimation many years. Depending on breed.
Sea Monkeys
Can sustain themselves in a state of deanimation for an indefinite period of time. Waiting for water to reanimate.
HUMAN
REVIVAL
HUMAN REVIVAL WARMING
WITHIN OUR GRASP Human Rev iva l_ 13:32
The New England Journal of Medicine published
a study which showed that with appropriate
rewarming fifty percent of people who have
suffered without a heart beat for up to three
hours can be brought back to life without any
neurological problems
As a cell biologist in cancer research, Mark
Roth studies genes, chromosomes and
autoimmune disease. But he’s best known
for his research into suspended animation.
Already, Roth has managed a world first
01
02
03
WITHIN OUR GRASP Human Rev iva l_ 14:32
Norway In the year 2000 a skier in Norway was trapped in an icy waterfall for two hours. He had no pulse and was found freezing. Seven hours later, still without a heartbeat he was brought back to life.
Duluth, MN In 2005 a woman in Duluth, MN was found frozen and without a pulse in her front yard. She was brought back shortly after with enough energy to be angry with hospitalstaff for not letting her leave.
Canada A little girl from Canada was found frozen and without a pulse after following her Father out of the house when he went to work. She also was later revived with no harm.
01°
02°
03°
WITHIN OUR GRASP ReAnimat ion_ 15:32
H2S
COLD
O2
RE-ANIMATION RECIPE FOR SUCCESS
WITHIN OUR GRASP ReAnimat ion_ 16:32
Hydrogen Sulfide can be found in nature that have the ability to become just a little immortal. They use a process of suspended animation to do so. This is the process where animals deanimate themselves appear dead.
Extreme Cold slows down to a stop, their breathing decreases and metabolic rate drops. After being in this state for a period of time they later wake up without harm.
Oxygen slows down to a stop, their breathing decreases and metabolic rate drops. After being in this state for a period of time they later wake up without harm.
WITHIN OUR GRASP ReAnimat ion_ 17:32
01If oxygen drops beneath 20% all living organisms are unable to sustain life and cosquentially die.
02 Suspended animations occurs When levels are reduced drastically to 10 parts per million.
03 The Oxygen concentration of 10 parts per million is conserved, and seen in a variety of different organisms
Is the nectar of life without it we will cease to exist.
Normal levels of oxygen must be adhered to at all times.
If not, then the inevitable result is death.
Mark Roth begun his experiments on the effects of
oxygen depravation by first testing on nematodes. When
oxygen levels were dropped below 20% the worms died,
However, when dropped to 10 parts per million a strange
thing happened. Suspended Animation.
Key Elements
Oxygen
2WITHIN OUR GRASP ReAnimat ion_ 18:32
2WITHIN OUR GRASP ReAnimat ion_ 19:32
WITHIN OUR GRASP ReAnimat ion_ 20:32
01Hydrogen Sulfide is extremely toxic to humans. When inhaled the gas will kill instantly.
02 Used as a chemical agent. in warfare during the battles of WWII.
03 Our bodies create hydrogen sulfide. The highest concentration is in our brain.
If inhaled in chemical accidents is known to make the
recipient collapse to the ground. The subject will appear
dead. However, if brought out to room air, the subject can
be revived without harm.
When injected into the body hydrogen sulfide will bind to
the same cells that oxygen binds to. Doing so, blocks the
adherence of oxygen and reduces our bodies need for it.
This reduction is so low that the body slips into the state
of suspended animation
Key Elements
Hydrogen Sulfide
WITHIN OUR GRASP ReAnimat ion_ 21:32
01If oxygen drops beneath 20% all living organisms are unable to sustain life and afterwards die.
02 Suspended animations occurs When levels are reduced drastically to 10 parts per million.
03 The Oxygen concentration of 10 parts per million is conserved, and seen in a variety of different organisms
The Norwegian skier was a huge inspiration to Mark Roth
and originally sparked his interest into the ability for
the human body to use cold as a catalyst for suspended
animation. Mark Roth experimented with replicating the
same results as the skier in his lab using nematodes.
What he found was the when body temperature was
lowered to 10 degrees Celsius the nematodes were kept
in a state of suspended animation.
Key Elements
Extreme Cold
WITHIN OUR GRASP ReAnimat ion_ 22:32
10˚
WITHIN OUR GRASP Lab Test ing_ 23:32
START
TEST
ING
LAB TESTING MAMMALS
When testing started Mark Roth was trying to replicate the same conditions that the skier in Norway was exposed to. All the parts of the suspended animation equation were introduced.
In order for the experiment to work mice had to be injected with hydrogen sulfide before being introduced to the extreme cold environment of ten degrees Celsius. Doing so lowered oxygen levels low enough to stop the metabolic rate.
Once in suspended animation the lab mice were frozen. Four hours later the mice were brought back with no harm to there body or metabolism. The experiment was a success
WITHIN OUR GRASP Lab Test ing_ 24:32
REAL WORLD APPLICATIONS
WITHIN OUR GRASP Appl icat ions_ 25:32
When testing started Mark Roth was trying to replicate the same conditions that the skier in Norway was exposed to. All the parts of the suspended animation equation were introduced.
In order for the experiment to work mice had to be injected with hydrogen sulfide before being introduced to the extreme cold environment of ten degrees Celsius. Doing so lowered oxygen levels low enough to stop the metabolic rate.
Once in suspended animation the lab mice were frozen. Four hours later the mice were brough back with no harm to there body or metabolism. The experiment was a success
WITHIN OUR GRASP Appl icat ions_ 26:32
BATTLEFIELD
Sometimes when soldier are wounded in the
arena of battle they don’t have the luxury of
being near a hospital. Suspended animation can
buy them the tie to be airlifted back to base.
TRAUMA PATIENTS
Even when an operation is a success trauma
patients can still suffer damage to there
internal organs. When in suspended animation
surgery can be performed while vital organs lay
dormant without the stress of surgery.
EMERGENCY VEHICLES Many patients in critical condition who have
suffered extreme trauma die in route to the
hospital. With an injection of hydrogen sulfide
these patients can be put under and reanimated
at the hospital. Giving their body the time it
needs to hold to life.
HEART FAILURE
In one model of heart attacks, animals given
hydrogen sulfide showed a 70% reduction in
heart damage. Compared to standard care we
receive in our hospitals.
LIST OF POSSIBILITIES
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01 DesignerKonstantine Pangalos
02 Instructor Megumi Kiyama
03 Project Within Our Grasp TED Confrence Identity for Suspended Animation
