WiSys: Development of Strategic Partnerships to Grow the Economy

through Technology Innovation

UW System Integrated Marketing and Communication ConferenceMay 31 and June 1, 2012

WiSys Technology FoundationMaliyakal John

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From Job Seekers to Job Creators

UW System Outcome

Institutions Students R&D Funding %4,392 (US Total) ~25 million ~$25 billion 100%

4,140 (4-2 year) ~17.5 million ~$3.8 billion 15%

24 (WI) ~110 thousand ~$1 million

Technology Transfer and Undergraduate Research

Economic Opportunity?

Pipe Dream?

WiSys at a Glance

• Affiliate of WARF

• Dedicated as the technology transfer office for 11 UW comprehensive campuses and 13 UW colleges

• Services began in 2005

• 5 member team– ~110,000 students (60%)

– ~3,500 faculty

Patent protect discoveries and transfer them to private industry to benefit the UW

WiSys 4-yr

WARF

WiSys 2-yr

UWMRF

WiSys Technology Foundation

UW System

• 26 campuses (13+13)• 2 research campuses• 182,000 students• 6,500 faculty members• $4.1 billion budget• 350-450 invention disclosures per year• 3 technology transfer offices

11 Comprehensives

~ 90, 000 students and 3,200 faculty~$750K in R&D budget

~25-30 invention disclosures

WiSys’ Roles

• Assist faculty and students to engage in research− Technology assessment− Funding− Collaborations− Technology transfer− Protect discoveries− Transfer technologies to private sector− Share revenue with inventor and campus

Develop a Long-Term IP Pipeline

WiSys Challenge

• No new additional resources

• R&D culture missing

• Lack of marketable product ideas

• Full-time teaching faculty

• Multiple, wide-ranging locations

How can we build a long-term IP pipeline and contribute to economic growth, scholarship and job creation in Wisconsin?

What We Have

• 300-400 faculty with technical expertise− Engineering− Material sciences− Chemistry− Computer sciences

• High-tech small companies with product concepts• Progressive clinical institutions with medical innovation ideas

State Resource

UW System Resource

Strategy: Build Strategic Partnerships

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Build a sustainable technology transfer program with minimal new resources

• Product ideas• Student internships • Clients• Marketing

• Healthcare challenges• Student internships• Clinical resources

• Funds• Public relations

Strategy

1. Facilitate the formation of Emerging Technology Centers to tap into the special expertise of faculty and prioritize resources for campuses

2. Build partnerships with the state’s high-tech small companies to develop products

3. Build partnerships with progressive healthcare/clinical organizations to develop innovative medical products

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Strategy

Wisconsin Small Company Advancement Program•Marketable product ideas•Connects with local/regional companies•Student engagement

• Advancing innovations• Scholarship• Entrepreneurship• Economic growth

WiS

CA

PW

isM

EF Wisconsin Medical Entrepreneurship Foundation

•Medical innovation ideas•Clinical resources•Faculty and student engagement

Emerging Technology Centersto tap into UW Faculty expertise

Emerging Technology Research Centers

Objectives:•Innovative R&D leading to marketable products

•Student internships as preparation for high-paying jobs

•Entrepreneurship training and startups

Scholarship

CollaborationsEconomic Growth

Jobs

Focus and prioritize

Emerging Technology Centers

UW-River FallsTissue and Cellular Innovation Center

UW-Stevens Point Wisconsin Institute for

Sustainable Technology

UW-PlattevilleNanotechnology

Center for Collaborative R&D

UW-StoutDiscovery Center

Dec, 2008

Mar, 2009

Sept, 2010

July, 2009

UW-La CrosseMedical

Innovation Center

Mar, 2011

Emerging Technology Research Centers Promote Specialized Research Expertise

Wisconsin Small Company Advancement Program (WiSCAP)

Joint R&D to develop products forsmall companies to drive Wisconsin business growth

WiSys obtained $2 million in state funding for WiSCAP in 2010

Companies with productIdeas, but lack of technicalexpertise

Faculty with technical expertise and resources

Product/IPLicenseRevenue sharing

WiSCAP Summary

• 21 projects initiated involving 17 companies and 9 campuses

• ~$2 million allocated to projects

• 12,083 hours of student internships

• 32 months of release time for 24 faculty members

• 16 high-paying jobs

• 10 WiSCAP projects advanced to prototypes and lab testing• 1 Option License signed• 3 Option Licenses under negotiation

Distribution of WiSCAP Projects

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WiSCAP: Mercury Removal From Fish Tissue

• Up to 80% mercury removed; flavor improved• Suitable for human and animal consumption• Market introduction in 2012

• $2.5 billion WI industry• 30,000 employed• 1.4 million licensed anglers• 400,000 out-of-state anglers per year

WiSCAP: Supercapacitors for the Energy Industry

• Nanomaterial-based technology• Increases energy density by ~20 fold• Field testing with Columbia ParCar

A $100 million opportunity

WiSCAP: Value Added Products from Cranberry

• Antiviral therapeutics• Animal feed supplements• Nutraceuticals

3 compounds with antiviral properties isolated. Characterization and animal studies underway.

WiSCAP: Economic Impact of the Wheelchair Project

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Employment Economic Impact

Taxes

Direct 80 $45.6 M

Indirect 90 $17.8 M

Induced 75 $9.3 M

Total 245 $72.7 M

Business $1.2 M

Household $418 K

Total $1.6 M

Advanced prototypes being built and human testing planned

Pressure Balanced Hydrogen Fuel Cell

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Prototypes to be installed at Columbia ParCar and Marquis Yachts for field testing

- Novel design- Low cost- No computer monitoring- Injection molding- Cell staking

Technical Expertise Needed for Medical

Technology Development

Technical Expertise Needed for Medical

Technology Development

Marshfield, Aurora, BayCare Clinics•Knowledge of patient care needs & opportunities•Clinical testing and trials•3 million patient visits•3,000 medical professionals

Marshfield, Aurora, BayCare Clinics•Knowledge of patient care needs & opportunities•Clinical testing and trials•3 million patient visits•3,000 medical professionals

UW, Private industry •Computer-aided design•Electrical, mechanical•Computer, chemistry •Prototyping•~400 faculty•90,000 students•Technology transfer

UW, Private industry •Computer-aided design•Electrical, mechanical•Computer, chemistry •Prototyping•~400 faculty•90,000 students•Technology transfer WisMEF

Advancing Medical Innovation through Partnerships

Marketable Medical

Technologies

Marketable Medical

Technologies

Wisconsin Medical Entrepreneurship Foundation (WisMEF)

Aurora Health Care

WiSys BayCare Clinic

Marshfield Clinic

WisMEF

Private Companies

- AquaCare H20- Botanic Oil Innovation- Fused Innovation- McDel Topology- mZeal- NovaScan- Perceptral- Procubed- VibeTech

Trade, State Organizations

- BioForward- WEDC- Morgridge Institute- EIGER Lab- Gateway College- Kenosha Area

Business Alliance (KABA)

- Quadripartite- State of Ingenuity

WisMEF

- UW-Platteville- UW-River Falls- UW-Stevens Point- UW-Stout- UW-Superior- UW-Whitewater

- UW-Eau Claire- UW-Green Bay- UW-La Crosse- UW-Oshkosh- UW-Parkside- UW Extension

- UW Colleges

Scholarship

StudentInternship

s

UW Clinics

Therapeutics

MedicalDevices

Digital Tools/ Rehabilitation

Digital Tools/Patient Care

Digital Tools/Hospital

Management

Polymers/Composites

Potential WisMEF Products

SanitizationProducts Diagnostics

Company

WisMEF: Low-cost 3D Catheter Location Using 2D Fluoroscopy for Cardiac Rhythm Management

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Aurora Health CareAnimal studiesClinical testing

Funding

APN LLC Tech development

SoftwareBusiness development

Funding

WiSys/UWSP3D imaging

SoftwareFunding

IP

WEDCFunding

Marketing

Warfarin: Designing a Safer Anticoagulant

• Redesigned 1st generation compounds based on pharmacogenomic studies• Shown efficacy in small animal studies• 2nd generation compounds being synthesized

Collaboration of UW and Marshfield Clinic

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Patient Assist Devices: UW & BayCare Clinic Collaboration

• Physician-bioengineer designed• Built by engineering students• Patient tested

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WisMEF Summary

• ~35 product ideas compiled

• $1 million in seed funds secured

• $1 million in state match funds being considered

• ~ 4 projects initiated

• Early prototypes built and tested

• Bioengineer recruitment in process

Pre-WiSys 1997-2005

(8 yrs)

WiSys 2005-2011 (6 yrs)

R&D funding $893K $3 millionDiscoveries 2 56$ per discovery $446,000 $53,000Startups 0 9Private equity 0 $2.6 millionHigh-paying jobs 0 32Licensing income 0 ~$1.4 million

Impact of WiSys

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Comprehensives

Impact Pre-WiSys

WiSys2005-2011

Total extramural R&D funds - $5.2 millionSBIR/STTR funding to startups - $800,000Student R&D internships - 33,000 hours

Emerging Technology Centers

0

5WI company partnerships - 21 WI Clinic partnerships 0 3

Impact of WiSys

Startups: Exceeding Expectations!

MycophyteDiscovery LLC, 2006Antimicrobial therapeutics

Xolve LLC, 2008Nanomaterials

McDel-Topology LLC, 2011Pharmaceutical products

Tomorrow River Biotechnologies, 2011Bioenergy

Shamrock Energy Corporation, 2010Supercapacitors

CoreTxt Plus LLC, 2011E-Books

Microionic Systems LLC, 2011Carbon products

NovaScan LLC, 2004Medical imaging

Foundry Solutions LLC, 2012Investment casting materials

Prentice Technologies LLC, 2012Digital tools

Strong Entrepreneurship in UW Comprehensives

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Institution Total Startups

Mayo Clinic 30Cleveland Clinic 35Baylor College of Medicine (~1 per year) 41John Hopkins (~ 8 per year) 32WARF (~4 per year) 56Medical College of Wisconsin 8WiSys (7 during 2010- 2012) 9

WiSys will Impact Wisconsin’s Future in an Unprecedented Way

Renewable Energy

Hydrogen fuel cellSolar energyCellulosic energySupercapacitorsBiodiesel

Heal

thca

re S

ecto

r

Digital technologiesPatient assist devices

Cancer detectionSurgical devices

TherapeuticsSafer food

AntimicrobialsNutraceuticals

Industrial Materials

Biodegradable plasticsNanomaterialsFoundry materials

UW

Achievements

• Developed and implemented a coherent strategy to advance innovation and entrepreneurship in undergraduate institutions

• Led formation of 5 Emerging Technology Centers to focus on cutting edge technology development

• Formulated and implemented an initiative to partner with high-tech small companies and advance product development

• Led the formation of a university-medical institutions-industry network to advance medical innovations and business growth

• Advanced entrepreneurship, resulting in the formation of 9 startup companies

Work in Progress

Engaging undergraduate institutions in R&D can have a significant economic impact

for Wisconsin and the country