white biotechnology: europe on the move

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    EUROPEAN CONFERENCE on BIOREFINERY RESEARCH Helsinki, 19 and 20 October 2006

    White Biotechnology:

    Europe on the MoveColja Laane

    Chairman, SusChem IB Steering GroupDSM

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    GreenGreenAgroAgro --FoodFood

    RedRedHealthHealth CareCare

    WhiteWhite

    IndustrialIndustrial

    Using natures toolset

    Biotech: for a Quality Life in a Sustainable Society

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    WB is Key to the Biobased Economy (KBBE)

    WB can deliversustainable products and

    energy without jeopardizing the

    environment.

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    Obvious Need for Sustainable Solutions

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    WB Value Chain

    Agricultural(by)products Sugars

    BiospecialtiesFood ingredientsPharmaceuticalsFine chemicals

    Biomaterials

    Fine chemicals

    Chemo-physical treatmentand/or enzymes

    Cell factory:Biocatalysis or

    Micro-organisms

    BiofuelsEthanolHydrogen Bulk chemicals

    Base Chemicals

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    World Chemical Sales (excl. Fuels)

    Chemicals sales 2004(Euro billions)

    27

    559

    183

    186

    137

    415

    100 9870

    0

    100

    200

    300

    400

    500

    600

    EU (25) Asia UnitedStates

    LatinAmerica

    Other** Rest of Europe*

    ChinaJapanRest of AsiaEU 10EU 15

    * incl. Switzerland, Norway, and other Central & Eastern Europe (excl. the new EU 10 countries)** incl. Canada, Mexico, Africa & Oceania

    E U 2 5 =

    5 8 6

    A S I A =

    5 0 6

    Source: ACC & Cefic

    World chemicals sales in 2004 is estimated at 1776 billionThe EU accounts for 33% of the total

    ~ 5 % i s

    b i o - b a s e d

    !

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    0

    5

    10

    15

    20

    25

    30

    35

    40

    45

    biofuels plant extracts pharmaingredients

    bulk chemicalsand polymers

    food/feedingredients

    oleochemicals enzymes others

    2005: 77 b EUR 2010: 125 b EUR

    Outlook White Biotech Sales (incl. Fuels)

    Source McKinsey, June 2006

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    Strategic Research Agenda

    February 2005

    November 2005

    August 2006

    Vision

    Strategic Research Agenda

    Implementation Action Plan

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    The development and production of novel,

    innovative products and processes in acost- and eco-efficient manner, usingincreasingly renewable raw materials

    VIA

    The discovery and optimization of strainsand biocatalysts .

    Main Objectives for WB Research

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    White Biotechnology: Research Areas

    5. Biocatalyst process design

    Bioreactor

    1. Novel enzymes and microorganisms 2. Microbial genomics & bioinformatics

    4. Biocatalyst function & optimisation 3. Metabolic engineering & modeling

    6. Innovative fermentation science &

    engineering

    7. Innovative downstream processing

    New bioproducts and biopolymers

    New active compounds Fine & specialty intermediates

    Commodity products Bio-based materials and polymers

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    Agricultural(by)products Sugars

    BiospecialtiesFood ingredientsPharmaceuticalsFine chemicals

    Biomaterials

    Fine chemicals

    Chemo-physical treatmentand/or enzymes

    Cell factory:Biocatalysis or

    Micro-organisms

    BiofuelsEthanolHydrogen Bulk chemicals

    Base Chemicals

    Strong points Europe:

    (Bio)chemical infrastructure Enzymes

    Biospecialties

    Building on Strength

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    Which Companies Will Be Successful ?

    Industrial Biotech Expert Survey 2006McKinsey&Company

    14

    13

    11

    11

    8

    8

    10

    10

    8

    7

    5

    5

    CompaniesNumber of times mentioned

    AcademiaNumber of times mentioned

    Novozymes

    DSM

    Cargill

    GargillDaniscoGenencor

    Degussa

    Novozymes

    DSM

    DuPont

    BASF

    DuPont

    Degussa

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    Implementation Action Plan

    February 2005

    November 2005

    August 2006

    Vision

    Strategic Research AgendaImplementation

    Action Plan

    www.suschem.orgwww.europabio.org

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    5. Biocatalyst process design

    Bioreactor

    1. Novel enzymes and microorganisms 2. Microbial genomics & bioinformatics

    4. Biocatalyst function & optimisation 3. Metabolic engineering & modeling

    6. Innovative fermentation science &

    engineering

    7. Innovative downstream processing

    New bioproducts and biopolymers

    New active compounds Fine & specialty intermediates

    Commodity products Bio-based materials and polymers

    Implementing the Research Areas

    W h o i s d o i

    n g w h a t, w

    h e r e, w h e n, w

    u d g e t ?

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    Biorefinery proposal

    2nd/3rd generation, integrated, diversified, zero-waste biorefinerypilot plant

    Study of societal, economical and environmental benefits

    StandardizedFeedstock

    Bioprocessinganddownstreamprocessingtechnology

    ApplicationResearch &Development

    Fine and specialty chemicals

    Performance materials

    Bio-based polymers

    Biofuels

    Bulk chemicals

    Proteins

    Oils/fatty acids

    I. Glucose, Starch

    Biomass supplyand conversiontechnology

    III.Crude biomassOrganic waste

    II. CelluloseLignocellulosics

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    Agroetanol 0,5

    Sudzucker 2,6

    Sauter 1,0

    Sauter 1,8

    Brasco 1,0

    Sekab 1,0

    Wessex Grain 1,3

    Abengoa 1,8

    Abengoa 1,5Abengoa 2,0

    Alcodis 1,0

    Blue Ocean 1,0

    Agrana 2,0

    Tereos 2,5

    Tereos 2,0

    Nawaro 2,0

    Projectplan

    Production

    British Sugar 0,7

    JV Abengoa 2,25

    Crystal Union 2,5

    Nedalco 2,2

    Roquette 2,0

    Sudzucker 3,0

    JV Alceste 1,0

    Abengoa 2,0

    BER 1,0

    Bioethanol Refineries in Europe

    Brazil 17 bl ethanol/y

    USA 17 bl ethanol/yEU 4 b l/y, incl. 70% biodiesel

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    Wheat & winery waste

    Bioethanol Refinery Examples in Europe

    Cellulose, 2006

    Wheat and barley waste Wood chips, pilot

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    Beyond Bioethanol.......

    Biodiesel and oleochemicals

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    Beyond Bioproducts.....

    Zero waste recycle generate microbial biomass reuse inorganics (e.g. CO 2, salts) valorize other organics (e.g. proteins, oils)

    Towards Integrated, Diversified, Zero-Waste Biorefineries

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    Beyond Research & Development

    A European Policy Agenda for the KBBE

    Establish a coherent European Policy Agenda for the KnowledgeBased Bioeconomy (KBBE)

    Stimulate and support innovation in plant science and industrialbiotechnology

    Promote production and use of bio-based products andprocesses

    Create awareness amongst all stakeholders

    Improve investment in WB SMEs

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    Supporting Biorefinery Development

    Set up EU-wide demonstration project(s)

    Integrated, diversified and zero-waste biorefinery

    Support the development of flexible research-oriented

    pilot plants

    Develop funding schemes in Europe for multiple

    company consortia to build small scale plants

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    By Alignment of European (Biorefinery) Activities

    Member State activities (Task Forces, Platforms, National Fora, etc.)ERA Net Industrial BiotechOther ETPs (Plants for the Future, Forestry, Biofuels)Framework Programme 7 themes (KBBE, Renewable Fuel production, etc.)Other EU initiatives (Biomass Action Plan, EU strategy for biofuels, ETAP,Sustainable Development, European Investment bank, eBIO, etc.)

    Creating Critical Mass, Synergy & Competitive Edge

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    EU nited in Diversity

    Member StatesERA-Net

    FP7

    ETPs

    www.nwo.nl

    www.europabio.orgwww.suschem.org

    Th F i

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    W h i t e

    The Future is.........