what is big data why it is important for healthcare providers now
DESCRIPTION
Big Data Challenge – From EMR’s to Translational Research Miroslav Končar, PhD Oracle Healthcare Business Development Director HL7 Croatia Chair, Associate Professor for Biomedical Informatics. What is Big Data Why it is important for Healthcare Providers Now. - PowerPoint PPT PresentationTRANSCRIPT
1© 2012 Oracle Corporation – Proprietary and Confidential
Big Data Challenge – From EMR’s to Translational Research
Miroslav Končar, PhDOracle Healthcare Business Development DirectorHL7 Croatia Chair, Associate Professor for Biomedical Informatics
2© 2012 Oracle Corporation – Proprietary and Confidential
What is Big Data
Why it is important for Healthcare Providers Now
3© 2012 Oracle Corporation – Proprietary and Confidential
MIT Big Data DefinitionWhat kind of big are we talking about here?
•U.S. Healthcare data is growing by 15 Petabytes a day – currently
•Up to 80% of healthcare data is currently unstructured.
5 million bytes (megabytes) Complete printed works of Shakespeare
20 billion bytes (gigabytes) Complete recorded works of Beethoven
10 trillion bytes (terabytes) Printed works in the Library of Congress
2 quadrillion bytes (petabytes) Google Earth information managed today
Typical person’s EHR~1MB healthy young, no images40MB middle-aged w/health issues, no images3-5GB with several health issues w/images
600 petabytes-10 exabytes (exabyte = billion gigabytes)
Estimated size of current US digitized patient data
1.5 million Estimated different medical devices (WHO)
Big Data: The management and use of ultra-large amounts of information
Management and use = efficient storage, search, analysis, visualizationUltra-large = >1Petabyte
4© 2012 Oracle Corporation – Proprietary and Confidential
• Chronic Disease Mgt.• Care Patterns• Population Health• Pay for Performance• Telemedicine• Patient Advocacy
• Customer Satisfaction• Disease Mgt. / Prevention• Social Media Interactions• Care / Process
Improvements• Marketing / Branding
Where Are Your Big Data Opportunities?Lower care cost and raise care quality
• Capacity Management• Staffing Optimization• Protocol Optimization• Process Efficiency• Supply Standardization• Cost Accounting
• Personal Preferences• Individualized Treatment • Biometrics• Data Management• Apply Research• New Clinical Protocols
Accountable Care Patient Engagement Personal & TranslationalMedicine
Operational Excellence
1 2 3 4
5© 2012 Oracle Corporation – Proprietary and Confidential
Why Oracle for Big Data
6© 2012 Oracle Corporation – Proprietary and Confidential
Big Data: Oracle’s DefinitionLarge volumes, high change velocity, complex variety, unknown value per byte
• Emerging sources of data, ie. sensor, machine generated, social, images, unstructured, etc., that exhibit any or all of “the four V’s”, potentially integrated with “traditional” structured data
• Healthcare providers can acquire, organize, process, analyze massive amounts of data, primarily through the use of scale-out on low-cost hardware, non-relational data models, APIs
TheFour
Vs
7© 2012 Oracle Corporation – Proprietary and Confidential
Oracle’s Leadership Across the Entire Healthcare Ecosystem Provides Us Unique Design Insights
R&D
ProductivityTranslational
MedicineQuality& Safety
PersonalizedCare
Participatory& Preventive Care
DiscoveryResearch
DiagnosticsPharma/BiotechMedical Devices
ClinicalResearch
Care Delivery
Care Management
Population/Global Health
“Value-based” healthcare
Outcomes
Collaborating across the life sciences and healthcare industries improves care, lowers costs and delivers greater value
Leading provider in:
BioPharma Clinical Trials Translational Research Healthcare Insurers CMS HIE & Insurance Exchanges Population Health Mgt. Healthcare Data Models Healthcare Analytics Interoperability Identity & Security Mgt.
© 2012 Oracle Corporation – Proprietary and Confidential 8
Our Translational Research Center (TRC) Can Be Added For Those Involved in The Research Domain
Strategic Development
Partners ?
Discovery Diagnosis Therapy Wellness
TRC accelerates discovery
Analytics extend into care delivery & daily life
Strategic Development
Partners
9© 2012 Oracle Corporation – Proprietary and Confidential
Customer Success Story
Erasmus MC, The Netherlands
10© 2012 Oracle Corporation – Proprietary and Confidential
Erasmus MC
• Erasmus Overview– The biggest Dutch University Medical
Centre located in the City of Rotterdam– A 1.200-bed, 1.4BUS$ operational
budget, 12.000 employees– Erasmus MC is one of the top 40 best
research institutes of the world
• Long years an Oracle customer– Full ERP (financials, procurement, HR,
learning management), Performance Management
– Technology – Database, Fusion Middleware
11© 2012 Oracle Corporation – Proprietary and Confidential
Translational Research in Erasmus
• Today - Clinical genetic testing is typically done for patients who are considered at risk of carrying genetic variations that are linked to a particular disease or disease predisposition.
• Next step - all variants in coding and non-coding DNA is mapped at once.
• The vast amount of knowledge that is offered by whole-genome sequencing can provide the scientics with new oppprtunities for disease management
• Barrier – how to manage vast amounts of data in real time, and manage all risks associated (security, perfromance, etc)
12© 2012 Oracle Corporation – Proprietary and Confidential
• Genome sequencing is time and resources demanding process– Complete human variants per sample generate 1.5TB of data
• Need to provide overview of all variants in genetically defined populations– Variations are displayed in the context of public knowledge
– Statistical quality measure for variants
– Disease association and functional impact
• Provide easy access to translational research scientists– Simple search web page to access variation data
– Summary reports for disease association
– Cytogenetic visual representation of variations
HuVariome Database – Business Problem
13© 2012 Oracle Corporation – Proprietary and Confidential
Why Oracle Exadata
Data storage is 10x smaller, Scanning process is 2000x faster
14© 2012 Oracle Corporation – Proprietary and Confidential
Conclusion
• Complete genomics offer new opportunities for disease management– Identifying novel DNA variants relevant for
Dx and therapy
– Companion diagnostics for targeted therapy
• Key areas of research – cancer conditions
• Visit Erasmus and HuVariome project at– http://www.erasmusmc.nl/
– http://www.youtube.com/watch?v=KVvVs2SVfHU
15© 2012 Oracle Corporation – Proprietary and Confidential