what are enzymes? proteins, with complex 3-d shapes have an active site which can bind a substrate...

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Help Chemical Reactions Occur Notice the enzyme is not used up in the reaction! Only a certain substrate will fit in the active site

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Page 1: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)
Page 2: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

What Are Enzymes?Proteins, with complex 3-d shapes

Have an active site which can bind a substrate (reactants)

Page 3: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

Help Chemical Reactions Occur

Notice the enzyme is not used up in the reaction!

Only a certain substrate will fit in the active site

Page 4: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

How?Allows bonds in substrate to be

broken more easily, with less input of energy

Page 5: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

Another Example

Page 6: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

Reaction Energy Diagrams

Activation Energy

Page 7: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

Activation EnergyInput of energy required to break

initial bonds and begin the reactionEven if reaction will release energy

Page 8: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

Enzymes Lower EaMake the transition state easier to

reach

Page 9: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

Endergonic vs. Exergonic

Page 10: What Are Enzymes? Proteins, with complex 3-d shapes Have an active site which can bind a substrate (reactants)

Specificity of Active Sites

Enzymes only catalyze substrates with a complementary shape

Any changes to the shape of the enzyme will disable the activity of the active site