welcome to the molecular medicine course!
DESCRIPTION
Welcome to the Molecular Medicine course!. Registration. General information Over-arching goals Roll call Course contents Information about KS library Coffee Course evaluation HT 2011 Study design - research application + presentations Seminar assignment Final examination - PowerPoint PPT PresentationTRANSCRIPT
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Welcome to theMolecular Medicine
course!
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Registration• General information• Over-arching goals• Roll call• Course contents• Information about KS library• Coffee • Course evaluation HT 2011• Study design
- research application + presentations• Seminar assignment• Final examination• Molecular Medicine - from bed to bench
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Course leader: Rachel Fisher08-517 732 45 [email protected]
Deputy course leader: Ewa Ehrenborg08-517 761 91 [email protected]
Teaching assistant: Louisa Cheung08-517 732 21 [email protected]
Department of Medicine, Center for Molecular Medicine,Karolinska University Hospital, L8:02
Course administrator: Eva MacDonaldDepartment of Medicine, Unit for Internal Medicine,Karolinska University Hospital, A3:0208-517 716 33 [email protected] hours daily 8.00am - 3.00pm
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Over-arching goals
• To integrate previously gained knowledge
• To stimulate team work
• To analyse, evaluate and interpret raw data
• To design a study and write a research application
• To provide “real life” experience
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Roll call
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Course set up
• Lectures usually 9am – 3pm (check venue!)• Labs/demonstrations/seminars usually in groups• Time scheduled for group work• Seminar assignment• Presentation of group work (research application)
at end of course• Revision time• Final written examination: 15th January
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Course contents (15 hp/ECTS)
Specific areas• Circulation, ischemia, metabolic syndrome, diabetes • Respiration, asthma, allergy • Endocrinology• Gastroenterology• Pathology• Clinical immunology / Clinical chemistry
Assignments etc.• Molecular biology lab• Research application• Seminar assignment• Workshops• Revision
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Course literature
• Text books from previous courses:
physiology, pharmacology, biochemistry,
molecular genetics, immunology
• Articles and links on the web page
• Lecture summary points (from lecturers)
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Information about KS libraryMarie Källberg
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Lab “Methods in Molecular Biology”
Lectures, demos, labs, exam
Research plan
Seminar assignment
Workshops
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Labs and Demonstrations • Lab: “Methods in Molecular Biology –
Theory and Practice”12/11 (introduction)27-29/11, 4-6/12 (lab)12-14/12 (analysis + statistics)9/12 (discussion + review)
• Angiography demonstration (14/11)
• Blood grouping lab (15-16/11)
• Lung/allergy demonstration (20/11)
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Labs • You must bring your own lab coat
Compulsory to have a lab coat to perform the labs
• If you have lost the lab coat you were given when you started the Biomedicine Programme, you can buy a new one (380kr):http://www.g-ess.se/ Tel: 08-449 85 70 (Stuvsta + Bromma)
• Some labs and demonstrations will be performed in active research labs- show consideration for those who work there
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Groups
• Blood grouping Thur 15/11, 13–16• Methods Mol Biol Tue 4/12
• Blood grouping Fri 16/11, 13–16• Methods Mol Biol Wed 5/12
• Blood grouping Thur 15/11, 9–12• Methods Mol Biol Tue 27/11
• Blood grouping Fri 16/11, 9–12• Methods Mol Biol Wed 28/11
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Course evaluation HT 2011Good
• Research application• Lab “Methods in Molecular Biology”• Seminar assignment• Course leaders/administration
Mixed• Clinical emphasis• Blood grouping lab• Lung/asthma/allergy demonstration• Lecturers
Bad• Lack of a course text book• Some repetition within lectures• Too many lectures
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New for HT 2012
• Some lectures + pathology seminars removed• Workshops• Modified set up for Lab “Methods in Molecular
Biology”• Place blood grouping lab in context• Modified lung/asthma/allergy demonstration• Final examination after Christmas• Presentation of research applications at end of
course
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Workshops • 3 workshops: Atherosclerosis
(12/11)Endocrinology
(21/11)Diabetes/Metabolism
(11/12)
• Questions/discussion topics handed out in connection with relevant lectures
• Self-study/discussion + review with teacher
• Preparation for the exam
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Evaluation of the course
• We rely on your feedback to improve the course
• Please give constructive feedback
• Evaluation forms (online)• Cinema ticket voucher if all evaluation forms
completed + submitted!
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• With class representativesWednesday 21st November, 12 noon
• With whole classThursday 17th January, 3pm
Who are the class representatives?
Course councils
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Forms of feedback
feedforward assignments
Research
application
whole-class feedback
Workshops
Research application
feedback on seminar assignment & exam
Pre-submission guidance and feedback
Research application
Workshops
Peer-to-peer to edit and
redraft
Methods in mol biol
reviewing progress with
students
Informing about feedback
Course councils and evaluations
Round-table feedback
Methods in mol biol
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Course language
• All literature in English
• Lectures in English
• All assignments may be written in either
English or Swedish
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Research application• Group assignment
• Choose a specific issue to focus on
• Design a research project
• Write a research application
• Present the project orally
• Answer questions
• Team work
• Realistic exercise
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Research application:groups and topics
• Groups 1-6 each split in 2
• 12 ”subgroups” of 3-4 people
• Each subgroup allocated a broad topic
• Detailed project chosen by the subgroup
• Discussions with and feed back from topic ”mentor”
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Research application – broad topics
• MicroRNA and vascular disease
• Aneurysm
• Thyroid diseases
• Thrombosis and haemostasis
• Mesenchymal stem cells and bone formation
• Cell death in metabolism
• Metabolism and cardiovascular disease
• Immunological aspects of gastric disease
• Inflammation in cardiovascular disease
• Allergy
• Diabetes and co-morbidities
• Vascular remodelling
2 topics/group, 3-4 people/research application
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Research applicationtopic lottery
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Seminar assignment
• Handed out at course start
• Group work / individual assessment
• Research based aspects, requires independent work
• Obtain appropriate information- lectures, discussions, web, articles ..…
• Time scheduled to prepare answer
• Presentation of assignment in seminar format:Groups 4, 5 + 6 Wednesday 28th NovemberGroups 1, 2 + 3 Wednesday 5th December
• Grading = pass / fail
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Time in schedule for Groups 1, 2 + 3to work with seminar assignment
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Time in schedule for Groups 4, 5 + 6to work with seminar assignment
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Examination
• Final examination: Tuesday 15th January Grades A-F
Questions testing knowledge + understanding
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Grading of the examination• F, Fx, E, D, C, B, A
• Goal-based assessment
• Evaluating the level of knowledge obtained not the amount of knowledge
• F, Fx = fail
• E = basic pass: identify, describe, list
• C, D = pass with merit: compare, explain connections, analyse, apply
• B, A = pass with distinction: theorise, hypothesise, reflect
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PrestructuralF
UnistructuralFx
MultistructuralE
RelationalC, D
Extended abstractB, A
One relevantaspect
Several relevantindependent aspects
Integrated intoa structure
Generalized tonew domain
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To pass the course …
• The student must obtain a grade of at least E for the written examination (5 hp)
• The student must also pass
– the seminar assignment (3 hp)
– the research application (3 hp)
– all labs and demonstrations (4 hp)
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Replacement assignments
• When compulsory parts of the course are missed, there are replacement exercises
• If written, these must be handed in by the last day of the course (18 January 2013)
• Next opportunity for submission = next course (HT2013)
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• Wednesday 21st November, 1pm
Lars-Arne Haldosén
Lena Hansson
Information about Masters Programme
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Molecular Medicine:from bed to bench
• Important clinical contact
• Translational research
• Cross-disciplinary
• “From bench to bed and back again”
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Please use the web page!