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Name of PI: NHIC I2D GrantAmount Applying for: Application Form

National Health Innovation Centre

Innovation to Develop (I2D) Grant

(NHIC I2D)

Full Proposal Application Form

SUBMISSION DETAILS

All applications must be fully endorsed by either the PI’s respective Office Of Research/Principal’s or Director’s Office/RI ED’s Office/Institutes or equivalent, before the submission deadline.

Applications must be submitted to NHIC through the Research Office of the Principal Investigator’s (PI’s) Healthcare Cluster (or in the case of SingHealth, applications must be submitted through the SingHealth Intellectual Property Office (SHIP)).

Only applications with the following two (2) submissions received by the Grant Secretariat by the respective deadlines will be accepted:

1. One softcopy submission containing the following documents to be emailed to Grant Secretariat at [email protected] by Closing Date, 5pm, with the subject header “Application ID_(Name of PI’s Healthcare Cluster)_(Name of PI’s Institution)”. Full Proposal Details (One word format without signatures and one PDF format with signatures)

2. One hardcopy submission, with signatures, to be sent by 3 working days after Closing Date, 5pm, to the following address:Attn: Grant SecretariatNational Health Innovation Centre61 Biopolis Drive #01-02 ProteosSingapore 138673

Full Proposal Application Form Version 4, dated 19 September 2016NHIC-I2D-FORM-1 of 22

Important: Relevant privileged or confidential information should be disclosed to help convey a clear understanding of the project. However, such information must be clearly marked in the proposal. All information is treated in confidence. The information is furnished to the National Health Innovation Centre (NHIC) with the understanding that it shall be used or disclosed for evaluation, reference and reporting purposes. If your application is not successful, this form will be destroyed after the retention period deemed as appropriate by NHIC.

mailto:[email protected]


1. Category of Proposala)

New Submission Application that has been previously submitted for NMRC research grants

(Application ID )

b) Please indicate the relevant category: Therapeutics BioTech & in vitro Diagnostics (IVD) MedTech Health IT & Software

2. ApplicantsPlease note the definitions of a Principal Investigator (PI), Co-Investigator (Co-I) and Collaborator, as indicated in the footnote. The terms of collaboration with overseas research institutions and companies must conform to NHIC’s & NMRC’s existing policies. (*please add more rows if required)

Name Role in Project (e.g. Principal Investigator1, Co-I2,

Collaborator3

Host Institution4

% Effort within

Project5

% Effort Within Own Work

Commitments6

Total 100%

Outline below the role of each team member and what expertise they bring to the Project.

1Definition of Principal Investigator (PI): A researcher who has the appropriate level of authority and the responsibility to direct the research project being supported by the grant. He/she is responsible and accountable for the proper conduct of the research project. One PI is allowed per application. He/she must hold a primary appointment in a local public hospital/public health institution/national speciality centre/medical school/Academic Medical Centre and be salaried by the institution.

2Definition of Co-Investigator (Co-I): An individual involved in the scientific development and execution of the project, typically devotes a higher percentage of effort to the project as compared to a collaborator and is considered key personnel. He/she needs to hold at least an adjunct position in a local public institution. Please note that a Co-I cannot be salaried by the grant.

3 Definition of Collaborator: An individual involved in the scientific development and execution of the project, and typically devotes a specific percent of effort to the project. Researchers from overseas institutions or companies can only participate as collaborators. Collaborators are not entitled to directly receive any portion of the grant.

4Definition of Host Institution: the body or institution or administering organization named in the Letter of Award as the “Host Institution” is the body responsible for undertaking and managing the Research and administering the Funding.

55NOTE: Represents percentage effort spent by the team members in the project relative to his/her other team members. The total in this column must add up to 100%.

66NOTE: Represents percentage effort spent by the team members on this project out of total work commitments (e.g. other grants, other teaching and administrative responsibilities, clinical work etc.)



3. Title of Project (Limit to 15 words)

4. Field of ProjectPlease complete the Health Research Classification (HRC) System below.

(A) Health Category You may select up to 5 categories from below. Please use minimum number of codes to reflect main focus of the research. Blood Musculoskeletal Cancer Neurological Cardiovascular Oral and Gastrointestinal Congenital Disorders Renal and Urogenital Ear Reproductive Health and Childbirth Eye Respiratory Infection Skin Inflammatory and Immune System Stroke Injuries and Accidents Generic Health Relevance Mental Health Other Metabolic and Endocrine

(B) Project Activity Code Please select up to 2 sub-codes from the following, eg, 2.1.

1 Underpinning Research1.1 Normal biological development and functioning 1.2 Psychological and socioeconomic processes1.3 Chemical and physical sciences1.4 Methodologies and measurements1.5 Resources and infrastructure (underpinning)

2 Aetiology2.1 Biological and endogenous factors2.2 Factors relating to physical environment2.3 Psychological, social and economic factors2.4 Surveillance and distribution2.5 Research design and methodologies (aetiology)2.6 Resources and infrastructure (aetiology)

3 Prevention of Disease and Conditions, and Promotion of Well-Being3.1 Primary prevention interventions to modify behaviours or promote well-being3.2 Interventions to alter physical and biological environmental risks3.3 Nutrition and chemoprevention3.4 Vaccines3.5 Resources and infrastructure (prevention)

4 Detection, Screening and Diagnosis4.1 Discovery and preclinical testing of markers and technologies4.2 Evaluation of markers and technologies4.3 Influences and impact4.4 Population screening4.5 Resources and infrastructure (detection)

5 Development of Treatments and Therapeutic Interventions5.1 Pharmaceuticals



5.2 Cellular and gene therapies5.3 Medical devices5.4 Surgery5.5 Radiotherapy5.6 Psychological and behavioural5.7 Physical5.8 Complementary5.9 Resources and infrastructure (development of treatments)

6 Evaluation of Treatments and Therapeutic Interventions6.1 Pharmaceuticals6.2 Cellular and gene therapies6.3 Medical devices6.4 Surgery6.5 Radiotherapy6.6 Psychological and behavioural6.7 Physical6.8 Complementary6.9 Resources and infrastructure (evaluation of treatments)

7 Management of Diseases and Conditions7.1 Individual care needs7.2 End of life care7.3 Management and decision making7.4 Resources and infrastructure (disease management)

8 Health and Social Care Services Research8.1 Organisation and delivery of services8.2 Health and welfare economics8.3 Policy, ethics and research governance8.4 Research design and methodologies8.5 Resources and infrastructure (health services)

5. Abstract In less than 300 words, describe in lay terms the aims, hypotheses, methodology and approach of the project proposal including its clinical impact. The abstract must be self-contained so that it can serve as a succinct and accurate description of the project proposal understood by a non-scientific/medical audience. Note that the abstract may be disclosed to other funding agencies. Please ensure the abstract is non-confidential.

6. Project ProposalIn no more than 15 pages (page limit excludes the CV section and reference section), please complete the following sections in the project proposal. Use Arial font size 11 for all text.

a. Background & Clinical Need Describe the background and the significance of the clinical need which the Technology will address. Describe the current approaches to the clinical need and their shortcomings. Who are the target patients? What is the incidence and/or prevalence? What is the total amount

spent per year to address the problem faced by these target patients?

b. Description and Impact of the Technology Give a concise description of the proposed Technology covering the following areas:

Describe the Technology and how it works. Detail the preliminary studies you have undertaken using the Technology. Why is the Technology the best solution for the clinical need? How will the Technology improve the patient experience and clinical outcomes? How does the Technology fit into the clinical workflow and current practices? How will the Technology reduce healthcare system costs? Define the regulatory strategy of the proposed Solution for entry into the first major market.



c. Uniqueness & Competitive Analysis of Solution

Identify competing technologies and how this Technology is superior. Outline the differentiating factor(s) of the Technology and the reason that industry would find the

Technology attractive.

d. Technology Development Plan Describe in detail the Development Plan for the Technology under this funding. Highlight any technical challenges of the proposed Development Plan. What is the contingency plan

where the technical challenges cannot be overcome? Describe the methods and management of the collaboration i.e. who will take the lead for each area,

a plan for regular meetings etc. Detail any agreements that would need to be put in place prior to starting the Development Plan.

e. Commercialisation Plan Articulate a clear commercialisation plan for the Technology (for example: out-licensing, the

formation of new commercial enterprises, co-development with industry funding (short and long term). Endorsements by potential commercial partners or investors in the project are encouraged).

f. Intellectual Property Management Provide details of the relevant Background IP for the Technology. Specifically address: i)

ownership ii) any agreements/licences covering the Background IP. Briefly describe any Foreground IP likely to be generated from the project. Describe how the Team intends to manage and exploit the IP it has filed/or intends to file. Provide a description of the Team’s track record of IP generation and commercialisation e.g. list of

patents filed (status), licences, spin-off companies etc.

7. Ethical Considerations and ContainmentFund disbursement is subjected to ethics approval if the project involves any of the below.

Please declare the participating institutions where study requiring ethics approval is conducted:

Please tick accordingly if programme involves any of the following:

a) Human Subject Yes No

b) Use of Human Material/ Yes No Animal Tissues or Cells

from Primary Donors (i.e. subject/volunteers recruited for project)c) Use of Commercially Available Yes No

Human Material/Animal Tissues or Cells

d) Animal Experimentation Yes No

e) Requirement for Containment Yes No

f) Multi-centre trial(s) Yes No

(If yes, please state all participating institutions/centres: )

A copy of the ethics approval is attached Yes No (Please forward a copy to NHIC)



8. Funding

8.1 Period of Support Requested Number of months: (Max. of 12 months)

8.2 Funding Request Total Amount (including Indirect Costs): SGD (capped at SGD 250K / project inclusive of 20% indirect costs)

8.3 BudgetList the budget of the funding requested in the format below and provide the relevant justifications. Please refer to NMRC Policy Document on Financial Regulations7.

8.3.1 ManpowerBudget for all the manpower required for the project including part-time personnel and those to be shared with other projects. State whether they are existing personnel in your institution or new staff to be recruited. Please use salary scales provided by the Institution as a reference. The cost should include annual increments, National Service increment, staff welfare, medical and other related benefits as per the Human Resource policies of your institution. Please note that a Co-I cannot be supported under Manpower.

Staff Category Existing/New No Remarks Total cost

Others: (please specify)

Total

8.3.2 EquipmentPlease budget for all scientific equipment you need to purchase to directly carry out the project. Indicate sharing of equipment with other projects, if any. For equipment costing more than $70,000 per item, indicate the estimated utilization of the equipment (e.g. 70% usage throughout the project period, and etc.)

Title of Specific Research Theme:

Qty EquipmentEstimated Utilization Rate for Equipment more than $70,000 (to be justified)

Unit Cost Sub-Total

Total

7http://www.nmrc.gov.sg/content/dam/nmrc_internet/documents/policiesAndGuidelines/Policy%20document%20on%20Finance%20Regulations.pdf



8.3.3 Other Operating Expenses (OOE)This covers other expenses directly related to the project such as the purchase of animals, consumables, laboratory manuals, literature searches, and maintenance of equipment. Conference travel will be funded only if a presentation or an article is presented and is capped at $6,000 per trip per person per requested year. Total Overseas Travel expenses shall not exceed $12,000 per project. The presentation or article must be directly related to the project and NHIC’s support must be acknowledged. Travel for commercialization activities will also be considered by NHIC on a case-by-case basis.

Title of Specific Research Theme:

Item Item Description Cost

Materials & Consumables

Overseas Travel

Others: (please specify)

*Please add rows for more items

Total

8.3.4 Indirect Research Cost (IRC)Indirect research cost is provided to PIs and Host Institutions, up to a maximum of 20% of the direct costs (less exceptional items). Please refer to Annexe A.

Item Description CostIndirect Research Cost provided to Host Institution

Total

Total Direct Costs: S

Grand Total including Indirect Costs: S

8.3.5 Justifications for Budget RequestedPlease provide breakdown details for all categories if this is not indicated in the previous tables.

Manpower Justifications

Equipment Justifications

Other Operating Expenses (OOE) JustificationsMaterials & Consumables

Overseas Travel

Other



9. Milestones/TimelineProvide the timeline and proposed milestones for the proposal. Detail reasonable 6-month and 1-year benchmarks for success.Shade the appropriate box(es) to indicate the month that a particular milestone is expected to be met. You can add or delete rows as appropriate.

Note: This section will be used to monitor the progress of the study and the milestones will be subject to review by NHIC during the grant periods. The progress of a project is a critical pre-requisite for the continued disbursement of funds.

Project Milestones/Deliverables M1 M2 M3 M4 M5 M6 M7 M8 M9 M10 M11 M12

1.

Milestone 1

Milestone 2

6-month milestone*

2. Milestone 3

3. Milestone 4

12-month milestone*

* Please ensure that the 6-month and 12-month milestones have quantifiable measures.



10. Expected OutcomesPlease indicate your realistic expectations on the outcomes of this grant. Please state ‘NA’ where indicator is not applicable.

Performance IndicatorsIndicate number /

value

Capability Indicators

Training R&D manpower for industry

Master’s research and PhD students trained and spun out to local industry as RSEs (Research Scientist & Engineer)

Research staff spun out to local industry as RSEs

Post-doctoral (within 3 years of the PhD award) researchers hired

Number of staff members first exposed to translational funding/innovation funding scheme under this Project*

Number of staff members exposed to translational funding/innovation funding scheme under this Project*

Invention disclosures*

Proof-of-concept studies in man*

Kick-start clinical treatments/therapeutics*

Patents filed*

Patents granted*

Patents commercialized*

Papers published in international journals (To state impact factor)

Presentations at international conferences

Awards for research at national and international level

Industry Relevance Indicators

R&D collaboration

Industry dollars received or in-kind contributions for Project*

Outcomes

Revenue from royalties and licensing agreements*

Spin-off companies registered*

Licences**

Follow on funding from another translational grant agency

New products or processes commercialized* *NHIC places special emphasis on these targets - you will need to satisfy at least two of these in order to be funded.



11. Prior Funding for Technology’s DevelopmentPlease provide the following details for funding from all sources that has contributed to the development of the Technology. List the funding source, the PI and the outcome of the grant. Attach additional pages if necessary.

(a) Support from any industry partner(s)Please provide details on the funding or other resources provided to the Development Plan by any participating industry partner(s).

Items Supported Source of Support

Form of SupportSupport Period

In-Kind8 Cash Contribution9

(SGD)Yes/NoYes/No

(b) List all grants applied for (e.g. NMRC, NRF, A*STAR, MOE, Clusters, etc) where outcome is pendingFor all NMRC grant applications, please indicate application ID. Please indicate all the grants applied of similar proposal where the applicant is involved as PI, Co-PI, Co-Investigator or Collaborator and provide any overlapping sections in the proposals as an Annex.

Title of Research and PI’s role in project Application ID

Funding

AgencyAmount of fund applied for ($)

Support Period (Year)

Highlight if there is any potential overlap of the above funding with this application to NHIC. Note that double-dipping is strictly prohibited. For any overlap, please explain how it would be handled.

12. Team members Attach the CV of each member of the research team. Please use the format below and indicate NA if the required information is not applicable (limit to 3 pages). Name Title NRIC/Passport No. Email Contact No Office Mailing Address Current Position (provide full details, e.g. joint appointments, other academic appointments including those

outside of Singapore) Percentage of time spent in Singapore every year Employment History Academic qualifications (Indicate degree title, award year and institution name) Research interests Publications in last 5 years (include only publications of direct relevance to study, stating impact factors) Patents held (related or unrelated to study) Scientific Awards Half page summary of research outcomes from all previous grants [eg. publications (full papers only for past

5 years and highlight papers relevant to study), patents, awards, etc].

For Co-Is and Collaborators, please include these two items: Peer reviewed funding awarded as PI in last 5 years (from local and foreign agencies)

o Grant quantum, start and end date, funding agency and field of research Current and previous support from NHIC, NMRC or other sources (include proposals pending approval)13. Undertaking by Principal Investigator

8 Please delete as appropriate

9Please specify amountFull Proposal Application Form Version 4, dated 19 September 2016NHIC-I2D-FORM-1 of 22


In submitting the NHIC I2D Full Proposal Application, the Principal Investigator and all Co-Investigator(s) & Collaborator(s) UNDERTAKE, on any Grant Award, to:

Declare that the Principal Investigator meets the eligibility criteria. Declare that all information is accurate and true.

Declare that he/she is free from any financial conflicts of interest.

Not send similar versions or part(s) of this proposal to other agencies for funding.

Submit supporting documents of ethics approval obtained from the relevant Institutional Review Board (IRB) and Animal Ethics Committee for studies involving human subjects/human tissues or cells, and animal/animal tissues or cells respectively, before any funding can be confirmed.

Be actively engaged in the execution of the research and comply with all laws, rules and regulations pertaining to safety, animal and human ethics, including the Singapore Good Clinical Practice guidelines.

Ensure that National Health Innovation Centre (NHIC) funding is acknowledged in all publications and presentations.

Ensure that all publications arising from research wholly or partly funded by NHIC will be forwarded to NHIC.

Ensure NHIC is notified of any commercialization of Intellectual Property generated wholly or partly under NHIC funding.

Ensure that the requested equipment/resources are not funded by another agency or research proposal.

Ensure that there is a reasonable effort in accessing available equipment/resources within the host institution or elsewhere within Singapore.

Adhere to NHIC’s & NMRC’s general guidelines on competitive funding and NHIC’s & NMRC’s Terms and Conditions.

------------------------------------------------------Name and Signature of PI Date:

----------------------------------------------------------------Name and Signature of Co-I/Collaborator* 10

Date:

----------------------------------------------------------------Name and Signature of /Co-I/Collaborator* Date:

(*Please add more if required)

10 *Delete as appropriate Full Proposal Application Form Version 4, dated 19 September 2016NHIC-I2D-FORM-1 of 22


14. Undertaking by Head of Department (HOD) & Host Institution of the PI

In submitting the Grant Application, the Institution UNDERTAKES, on any Grant Award, to:

Discuss with immediate supervisor of applicant that the following will be complied with:

o The proposed research will be conducted in the host institution

o Adequate resources will be provided to the PI for the entire grant period (e.g. lab space)

o The PI is independently salaried by the institution for the entire period of the grant

o The research abides by all laws, rules and regulations pertaining to national and the institution's research operating procedures and guidelines

o Confirm the accuracy and completeness of information submitted, including budget, ethics, other funding sources, etc.

o Confirm that budget is clear (e.g. no double funding/ excessive purchase of equipment), and is aligned with host institution HR and other policies

o There is no financial conflict of interest

-----------------------------------------------------------Name and Signature of Head of Department11

--------------------------------------------------------- Name and Signature of Director of Institution12

---------------Date

---------------Date

11 If the PI is the Head of Department, UNDERTAKING by the HOD’s Reporting officer is required.

12 If the PI is the Director of the Institution, UNDERTAKING by the Director’s Reporting officer is required.Full Proposal Application Form Version 4, dated 19 September 2016NHIC-I2D-FORM-1 of 22


Annex 1 Budgeting Requirements

Type of Expenses Description

EOM Related Expenses

Salaries, CPF and fringe benefits including medical, dental, contribution to welfare fund, etc.

Allowable as part of overall compensation to employees provided such costs are incurred under formal established and consistently applied policies of the host Institution.

The manpower funded as part of the direct cost should be directly involved in the research work of the project.

The salaries offered to staffs should be reasonable, in line with local market benchmarks and comply with formal established pay scale of the host Institution that is consistently applied regardless of the source of funds.

Core manpower fundable under the direct cost only:

- Research fellow,

- Research engineer/scientist,

- Research assistant/associate,

- Specialist laboratory technician,

- Biostatisticians,

- Nurses, and

- Technical officer.

All other manpower will fall under IRC.

Case by case consideration will be given if the PI can justify that the required manpower should be funded under the direct manpower cost.

Annual leave Allowable for employees. The number of days of leave accorded to staff must be in accordance with formal policies of the host Institution that is consistently applied regardless of the source of funds.

Bonus / Incentive payments,

Allowable as part of a total compensation package, provided such payments are reasonable and are made according to a formal policy of the host Institution that is consistently applied regardless of the source of funds.

Staff insurance Allowable as part of overall compensation to employees provided such costs are incurred under formal established and consistently applied policies of the host Institution.




Participation of overseas experts

Allowable.

Expenses incurred for overseas experts invited to participate in the project and staying in Singapore for at least 6 months per year must be budgeted separately in the project budget under the category for Visiting Professor/Expert.

For other overseas experts staying for less than 6 months per year, the cost of his/her stay is allowable if the costs are specifically provided for and approved in the project grant.

Examples of such costs are honoraria, salaries, staff relocation, settling-in allowances and other related cost

For staff relocation, settling-in allowances, etc, it will be allowable for senior expatriate R&D staff if the costs are specifically provided for and approved in the project grant.

However, superannuation contributions for such staff are not allowed under both direct cost and IRC.

Staff recruitment and related cost

Not allowable under direct cost. Examples of such costs are advertisement and recruitment agency cost.

These expenses can be claimed under IRC.

Stipends and course fees of full-time and/or part-time graduate research students

Not allowable under both direct cost and IRC.

Only student attachment and top-up for research students are fundable under IRC.

PI’s & co-investigators’ EOM

Not allowable under both direct cost and IRC.

Equipment Related ExpensesNew equipment Allowable if needed specifically for the project.

Each equipment must be individually identified and its total cost inclusive of bank charges, delivery and installation, etc estimated.

For equipment costing more than S$70,000, they will be classified under “Exceptional Items” (see para 2.4 to 2.6 in the Administrative Guidelines). For purchase of such equipment, 3 quotations must be provided in the budget along with full justifications for the need to purchase the equipment.




General purpose IT and communication equipment

Not allowable under direct cost. Examples of such costs are computers, office productivity software, PDAs, mobile phones, etc.

The cost of such equipment can be claimed under IRC. The procurement of such equipment must be reasonable and make according to the formal established and consistently applied policies of the host Institution.

General furniture and office equipment

Not allowable under direct cost. Examples of such costs are fax machines, photocopier machines, workstations and printers, etc.

The cost of such items can be claimed under IRC. All procurement of such items must be reasonable and make according to the formal established and consistently applied policies of the host Institution.

Consumables Related ExpensesConsumables Allowable.

Examples of such costs are supplies and materials, laboratory consumables, animals and drugs which are necessary for the successful execution of the funded project.

All procurement of such items must be reasonable and are made according to the formal established and consistently applied policies of the host Institution.

Drug costs and medical procedures for patients and volunteers

Allowable.

OOE Related ExpensesBank charges Allowable as long as it is specifically related to the payments for

consumables and equipment used in the project.

Customs and import duties

Allowable as long as it is specifically related to importation of consumables and equipment used in the project.

Books and specialised journals relevant to the research

Allowable.

If the host Institution has a library, books and journals should be obtained from the library and PI should refrain from purchasing the same books or subscribing to such journals.

GST Allowable for expenses incurred for the project.




Local & Overseas conferences

Allowable, if conference is directly relevant to the research area or necessary to accomplish the project objectives for PI, co-investigators, collaborators, researchers and research students funded under the project grant.

The expenses for such conferences may include registration fee for the conference, air tickets, per diem and other allowances. Such payments should be in accordance with the formal policies of the host Institution.

If the conferences are conducted overseas, the travel policy of the host Institution must be consistently adhered to. However, total expenses for travel per trip per person per requested year must not exceed $6,000. The total expenses under I2D Grant is capped at $12,000 per project.

The PI must submit a copy of the abstract when claiming reimbursement for such expenses and append to their annual/ final report.

Photocopying and printing charges

Allowable.

Publications Allowable.

Page charges for publication of manuscript in professional journals are allowable if they adhere to the formal established policy of the host Institution, where applicable.

The costs of reprints and publishing in other media, such as books, monographs and pamphlets are not allowable unless specific approval has been obtained from the NMRC.

Repairs and maintenance of research equipment

Allowable if specifically budgeted for in the project and the equipment is used extensively for the benefit of the research project.

Stationery & printer consumables

Allowable.

Examples of such costs are printer cartridges, etc.

Training Allowable.

Funding for training is allowable for the PI, co-PIs and the collaborators. For funding of the research personnel, it should be restricted to the personnel employed under the project grant and for training that is of direct




benefit and specific to the research project.

Transportation, postage & courier services

Allowable.

This includes postage, courier and freight charges for bringing in equipment and specialised research consumables and reimbursement for staff transportation.

Use of services, equipment rental or lab spaces within the host Institution’s central facilities

Allowable.

The cost for the use of the services and central facilities owned by the host Institution such as animal holding units, central laboratory services are allowable and must be based on host Institution’s fee schedules which are consistently applied regardless of source of funds.

Host Institution may be requested to certify that the fee structure is applied consistently.

Payment to volunteers and research patients and other related cost

Allowable for payment to volunteers and research subjects provided this is the scope of the research and has been provided for and approved in the grant. Examples of such payments may include inconvenience fees, transport and meal reimbursement, etc.

Press advertisements for patients are allowable under IRC only.

Audit fees Not allowable under direct cost. This includes both internal and external audit fees.


Entertainment & Refreshment

Not allowable under direct cost.


Fines and penalties Not allowable under both direct cost and IRC.

Insurance premiums Not allowable under direct cost. Examples of such costs are for equipment, workmen compensation, professional indemnity of researchers funded under NMRC/NRF grants.





The host Institution is responsible for the insurance of the equipment, relevant workmen compensation and professional indemnity insurance which are in line with the host Institution’s risk policies.

Legal fees Not allowable under direct cost and IRC.

Outsourcing Not allowable under direct cost unless specifically provided for and approved in the grant.

Overhead expenses - rental, utilities, telephone charges, facilities management, repairs and maintenance, etc



Patent-related expenses Not allowable under direct cost and IRC.

Such cost should be borne by the host Institution.

Professional fees (including fees to consultants)



Professional membership fees of PIs /RFs /RAs funded from the grant



Staff retreat Not allowable under direct cost.


Cost of capital works and general infrastructure

Not allowable under direct cost unless specifically provided for and approved in the grant.



Non-Fundable ItemsEOM Related Expenses1 PI’s & co-investigators’ EOM

2 Stipends and course fees of full-time and/or part-time graduate research students

3 Superannuation contributions for senior expatriate R&D staff

OOE Related Expenses4 Fines and penalties

5 Legal fees

6 Patent-related expenses

Others7 Non cash items such as depreciation cost, amortization cost, loss on revaluation, etc.

Exceptional Items (not taken into account for IRC computation):

i. Major equipment costing more than S$70,000;

ii. Intellectual property that is needed to carry out the proposed R&D work;iii. Subcontracting of non-research work (e.g., the development of tools for the

research);iv. Payment to volunteers and research patients; and

v. Infrastructural work that is approved (following strong justifications) as a direct cost of the research grant.



APPENDIX

Summary

Item Direct Cost

Indirect Research

CostNon

Fundable

Specifically provided for

and approved in grant

EOM Related ExpensesSalaries, CPF and fringe benefits including medical, dental, contribution to welfare fund, etc. √

Annual leave / Bonus / Incentive payments √

Staff insurance√

Participation of overseas experts√

Student attachment and top-up for research students √

Staff recruitment and related cost√

PI’s & co-investigators’ EOM√

Stipends and course fees of full-time and/or part-time graduate research students

√

Superannuation contributions for senior expatriate R&D staff √

Equipment Related ExpensesNew equipment

√

General purpose IT and communication equipment √

General furniture and office equipment√

Consumables Related ExpensesConsumables (e.g. supplies and materials, laboratory consumables, animals and

√



APPENDIX

Item Direct Cost

Indirect Research

CostNon

Fundable



drugs)

OOE Related ExpensesBank charges

√

Customs and import duties√

Books and specialised journals relevant to the research √

GST√

Local & overseas conferences√

Outsourcing√

Photocopying and printing charges√

Publications√

Repairs and maintenance of research equipment √

Stationery & printer consumables√

Training√

Transportation, postage & courier services√

Use of services, equipment rental or lab spaces within the host Institution’s central facilities √

Volunteers and research patients and other related cost √



APPENDIX

Item Direct Cost

Indirect Research

CostNon

Fundable



Press advertisements for patients√

Audit fees√

Entertainment & refreshment√

Insurance premiums√

Overhead expenses (eg. rental, utilities, telephone charges, facilities management, repairs and maintenance, etc) √

Professional fees (including fees to consultants) √Professional membership fees of PIs /RFs /RAs funded from the grant √

Staff retreat√

Fines and penalties√

Legal fees√

Patent-related expenses√

Cost of capital works and general infrastructure √

Others

Non cash items such as depreciation cost, amortization cost, loss on revaluation, etc √


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