Applications overviewBiotechnology and pharmaceutical

BioPure specialises in advanced single-use, fluid path components and tube connector systems for biopharmaceutical end users and OEMs.

Specialising in the design and manufacture of sanitary fluid path components which guarantee product consistency and process security. Our gasket range utilises market leading technology to improve sterility within pharmaceutical and biotechnology production process, reducing validation risks.

Watson-Marlow Fluid Technology Group is unique in being able to support every biotechnology and pharmaceutical step to ensure critical fluid transfer requirements are achieved. Whether performing pH control or gentle transfer of live cells, we have a solution.

Throughout upstream and downstream, we provide accuracy, reliability and purity for all fluid handling needs.

Biotechnology and pharmaceutical products

From benchtop to production scale, Watson-Marlow peristaltic pumps and OEM solutions provide total process confidence and security by providing traceability, ease of validation, superior flow rate stability and metering accuracy.

Watson-Marlow’s range of high purity silicone and TPE tubing complements our peristaltic pumps. Our pump and transfer grade tubing enables our customers to deploy easy to validate end-to-end fluid path solutions from a single reliable source.

Flexicon fill finish equipment facilitates filling and easy product changeover. Our highly flexible solutions from stand-alone units to fully automatic filling systems, with consistent contact materials, enable process scaling using the same technology and validation.

ASEPCO Weirless Radial diaphragm valves are designed for use in the most demanding high-purity fluid streams in biopharmaceutical applications.

Patented valve architecture means no leakage or contamination of valuable products.

Specialist in the design and manufacture of PTFE-lined flexible hoses. Hoses have excellent chemical resistance and strong resistance to steam sterilising, representing important advantages in many applications.

WFI

POWDERTRANSFER

LIQUIDTRANSFER

MIXER

ST

ER

ILE

FIL

TR

AT

ION

100500600700

WFILIQUID

TRANSFER

TRANSFERVESSEL

MIXER

ST

ER

ILE

FIL

TR

AT

ION

100500700 600

600

700

5L>

MEDIA PH ACID/BASE

ANTI-FOAM

100 100

500

500

500

500 500

600

700 600

BIO-REACTOR

BIO-REACTOR

BIO-REACTOR

BIO-REACTOR

20L>

BIOREACTOR

100L>

SEED CULTURE

100 100 100

MEDIAPH ACID/BASE

ANTI-FOAM

ANTI-FOAM

PH ACID/BASE

MEDIA

BUFFER

PERFUSION/CLARIFICATION

CONCENTRATION/DIAFILTRATION

HOLDVESSEL

TRANSFERVESSEL

500

600

700

600 700

600

HOLDTANK

CAPPINGFILLING

AIR

LIQUIDWASTE

ULTRAFILTRATION/CONCENTRATION

CENTRIFUGE

MIXER MIXER

700

600

700

500

600 700600 700

STOPPERS CAPPING

SEED TRAIN

600

700

TRANSFERVESSEL

MEDIA PREPARATION BUFFER PREPARATION

FERMENTATION HARVEST PURIFICATION FILL/FINISH

CH

RO

MA

TO

GR

AP

HY

600

ST

ER

ILE

FIL

TR

AT

ION

TRANSFERVESSEL

STERILE FILTRATION

700

ASEPCO PRODUCTS FOR STAINLESS STEEL SYSTEMS

General layout only, some detail has been omitted for clarity.

WFI

POWDERTRANSFER

LIQUIDTRANSFER

MIXER

ST

ER

ILE

FIL

TR

AT

ION

100500600700

WFILIQUID

TRANSFER

TRANSFERVESSEL

MIXER

ST

ER

ILE

FIL

TR

AT

ION

100500700 600

600

700

5L>

MEDIA PH ACID/BASE

ANTI-FOAM

100 100

500

500

500

500 500

600

700 600

BIO-REACTOR

BIO-REACTOR

BIO-REACTOR

BIO-REACTOR

20L>

BIOREACTOR

100L>

SEED CULTURE

100 100 100

MEDIAPH ACID/BASE

ANTI-FOAM

ANTI-FOAM

PH ACID/BASE

MEDIA

BUFFER

PERFUSION/CLARIFICATION

CONCENTRATION/DIAFILTRATION

HOLDVESSEL

TRANSFERVESSEL

500

600

700

600 700

600

HOLDTANK

CAPPINGFILLING

AIR

LIQUIDWASTE

ULTRAFILTRATION/CONCENTRATION

CENTRIFUGE

MIXER MIXER

700

600

700

500

600 700600 700

STOPPERS CAPPING

SEED TRAIN

600

700

TRANSFERVESSEL

MEDIA PREPARATION BUFFER PREPARATION

FERMENTATION HARVEST PURIFICATION FILL/FINISH

CH

RO

MA

TO

GR

AP

HY

600

ST

ER

ILE

FIL

TR

AT

ION

TRANSFERVESSEL

STERILE FILTRATION

700

ASEPCO PRODUCTS FOR STAINLESS STEEL SYSTEMS

General layout only, some detail has been omitted for clarity.

2

WFI

POWDERTRANSFER

LIQUIDTRANSFER

MIXER

ST

ER

ILE

FIL

TR

AT

ION

100500600700

WFILIQUID

TRANSFER

TRANSFERVESSEL

MIXER

ST

ER

ILE

FIL

TR

AT

ION

100500700 600

600

700

5L>

MEDIA PH ACID/BASE

ANTI-FOAM

100 100

500

500

500

500 500

600

700 600

BIO-REACTOR

BIO-REACTOR

BIO-REACTOR

BIO-REACTOR

20L>

BIOREACTOR

100L>

SEED CULTURE

100 100 100

MEDIAPH ACID/BASE

ANTI-FOAM

ANTI-FOAM

PH ACID/BASE

MEDIA

BUFFER

PERFUSION/CLARIFICATION

CONCENTRATION/DIAFILTRATION

HOLDVESSEL

TRANSFERVESSEL

500

600

700

600 700

600

HOLDTANK

CAPPINGFILLING

AIR

LIQUIDWASTE

ULTRAFILTRATION/CONCENTRATION

CENTRIFUGE

MIXER MIXER

700

600

700

500

600 700600 700

STOPPERS CAPPING

SEED TRAIN

600

700

TRANSFERVESSEL

MEDIA PREPARATION BUFFER PREPARATION

FERMENTATION HARVEST PURIFICATION FILL/FINISH

CH

RO

MA

TO

GR

AP

HY

600

ST

ER

ILE

FIL

TR

AT

ION

TRANSFERVESSEL

STERILE FILTRATION

700

ASEPCO PRODUCTS FOR STAINLESS STEEL SYSTEMS

Copyright © 2016 Watson-Marlow Fluid Technology Group

600 700

100 500

Watson-Marlow Pumps

Flexicon

Watson-Marlow Tubing

ASEPCO

BioPure

Pumpsil / PureWeld XL / Bioprene tubing

Watson-Marlow process pumps

Flexicon filling and capping

Accusil tubing

asepticsu fluid path

BioPure components

puresu fluid path

Weirless Radial diaphragm valves

Platinum-cured silicone braid hose

High purity Platinum-cured silicone gaskets

FlowSmart

Peristaltic bioprocessing pump

Aflex PTFE flexible hose

Aflex Hoses

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Disclaimer: The information contained in this document is believed to be correct but Watson-Marlow Limit-ed accepts no liability for any errors it contains and reserves the right to alter specifications without notice. It is the users responsibility to ensure product suitability for use within their application. Watson-Marlow, LoadSure, Qdos, ReNu, LaserTraceability, Pumpsil, PureWeld XL, Bioprene, Marprene are registered trademarks of Watson-Marlow Limited. Tri-Clamp is a registered trademark of Alfa Laval Corporate AB. GORE and STA-PURE are registered trademarks of W.L. Gore and Associates.

Watson-Marlow Fluid Technology Group

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