warm up write down as much as you know about the endocrine system. ◦ what is it made up of? ◦...
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Warm UpWrite down as much as you know
about the endocrine system.◦What is it made up of?◦Where is it located?◦What is its purpose?
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Objective:◦SWBAT
Explain why steroid hormones act directly on target organs while amino acid hormones act through secondary messengers
Agenda:◦Notes: Intro to Endocrine◦Hormone Chart Relay◦Closing
Homework:◦Essay due Monday 3/17
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Notes: Intro to EndocrineOverviewRelatively small and unconnected glands
◦ Produce:Slow acting chemical messengers called
hormones◦ Which act on:
Specific locations called target organs
Two Types of HormonesAmino-acid based—polar
◦ All but those produced by adrenal cortex and gonadsSteroid-based—nonpolar
◦ Those produced by adrenal cortex and gonads
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Hormone Release◦ Hormonal—hormones from one gland stimulate the release of
hormones from another gland◦ Humoral—too low or too high of an amount of nutrients in the
blood signal release of hormones◦ Neural—stimulation of the nervous system stimulates release
of hormones
Mechanisms of Hormone Action Direct Gene Activation (nonpolar steroid hormones)
◦ Diffuse through target’s plasma membrane into nucleus where they begin DNA transcription and translation of new proteins
Second-Messenger System (polar amino acid hormones)◦ Cannot diffuse through target’s plasma membrane◦ Instead, must bind to receptor on surface of target, activating
a secondary messenger
Hormone Regulation Negative feedback—hormone levels rise until certain
point; then high levels “tell” body to stop producing more hormone
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Hormone Chart Relay
You will be assigned to 1 of 7 groups of 4 students◦ You will be responsible for researching a total of 3
assigned hormones◦ But you will only be given 1 hormone at a time◦ You cannot move to the next hormone until the first
hormone information is correctAssign the following roles
◦ Researcher— determine the function (www.nlm.nih.gov and www.mayoclinic.org)
◦ Scribe—write down the function◦ Classifier—determine the type of hormone and what its
regulated by◦ Typer—have slip checked by Ms. McGowan and type
into class chartFinally, we will review our chart as a class
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Warm UpWhy do steroid hormones act
directly on target organs while amino acid hormones act through secondary messengers?
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Objective:◦SWBAT
Explain the stimulation, action, and regulation of one hormone
Agenda:◦Review: Intro to Endocrine◦Hormone Chart◦Hormone Scavenger Hunt◦Closing
Homework:◦Essay due Monday 3/17
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Label the glands below using the following terms:
Hypothalamus, pituitary, and pineal
Thyroid and parathyroid
ThymusAdrenalPancreasOvariesTestes
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http://wps.aw.com/bc_campbell_concepts_6_oa/95/24514/6275825.cw/index.html
Use the video below to label your glands:
http://www.pennmedicine.org/encyclopedia/em_DisplayAnimation.aspx?gcid=000048&ptid=17
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Hormone ChartFollow along as we fill out the
hormone chart we made yesterday
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Hormone Scavenger HuntIndividually, you will complete a
scavenger hunt around the roomStart at any station write down
the station #, question, and your answer
Then, search around the room for your answer this will lead you to your next question
You will be graded on the order you visit each station (There is only one way!)
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Warm UpChoose one hormone you learned
about yesterday and explain its function.
Consider how it is stimulated, how it acts, and how its regulated.
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Objective:◦SWBAT
Explain how the imbalance of one hormone causes at least one disorder
Agenda:◦Hormone Scavenger Hunt◦Guided Notes: Endocrine Development
and Issues◦Closing
Homework:◦Essay due Monday 3/17
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Hormone Scavenger HuntIndividually, you will complete a
scavenger hunt around the roomStart at any station write down
the station #, question, and your answer
Then, search around the room for your answer this will lead you to your next question
You will be graded on the order you visit each station (There is only one way!)
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Warm UpChoose one hormone we have
previously learned about.What would happen if there was
too much of this hormone? Too little?
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Objective:◦SWBAT
Explain how the imbalance of one hormone causes at least one disorder
Agenda:◦Guided Notes: Endocrine Development
and Issues◦Application Questions◦Closing
Homework:◦Finish Application Questions
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Notes: Endocrine Development
Endocrine glands begin deteriorating in old age◦Example: Menopause—deterioration
of gonads causes loss of ability to bear children, hot flashes, etc.
Also, during pregnancy, the placenta produces human chorionic gonadotropin (hCG) that stimulates continued production of estrogen and progesterone
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Notes: Endocrine IssuesSterility—under secretion of FSH
and/or LHGigantism--over secretion of GH in
children affects long bonesAcromegaly—over secretion of GH in
adults affects skull, hands, and feetPituitary dwarfism--under secretion
of GHDiabetes insipidus—under secretion
of ADH leads to excessive urination (polyURIA) and thirst (polydipsia)
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Notes: Endocrine IssuesGoiter—excessive release of T3/T4 due to a
lack of iodine causes a noticeable enlargement of the thyroid
Creatinism—under secretion of T3/T4 due to under secretion of TSH in children leads to dwarfism and mental retardation
Myxedema—under secretion of T3/T4 due to under secretion of TSH in adults leads to physical and mental sluggishness
Graves’ disease—over secretion of T3/T4 due to a tumor leads to increased metabolism and bulging eyes
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Notes: Endocrine IssuesTetany—low blood calcium leads to
overactive neurons and therefore muscle spasms
Hyperparathyroidism—high blood calcium leads to bone fragility and spontaneous fractures
Addison’s disease—under secretion of adrenal cortex hormones leads to a bronze tone and muscle weakness
Hyperaldosteronism—over secretion of ALDOSTERONE leads to hypertension and edema
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Notes: Endocrine IssuesCushing’s syndrome—over secretion
of adrenal cortex hormones leads to swollen face and hump of fat on upper back
Diabetes mellitus—under secretion of insulin leads to excessive urination (polyURIA) and thirst (polydipsia)
Masculinization—over secretion of sex hormones leads to excessive male features in both sexes
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Application QuestionsWork together to answer your
application questionsWhen you finish, we will review
them as a class
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ClosingPick one of the diseases you
learned about today and explain how it is caused by imbalance of 1 hormone.
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Warm UpPick one of the diseases you learned
about yesterday and explain how it is caused by imbalance of 1 hormone.
Take out your Application Questions for completion points
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Objective:◦SWBAT
Explain the difference between Type 1 and Type 2 Diabetes mellitus
Agenda:◦Review Application Questions◦Bluff◦Closing
Homework:◦Endocrine Systems Quiz Tomorrow
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Application QuestionsFollow along as we review your
endocrine application questions Make sure you have the correct
answers down!
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BluffRaise your hand if you have ever
played BluffWho would like to explain the
rules?
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Closing Compare and contrast type 1 and
type 2 diabetes.
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Warm UpAny last questions before your
endocrine system quiz?
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Objective:◦ SWBAT
Score >80% on their endocrine system quiz Explain why blood is red, but appears blue
Agenda:◦ Endocrine System Quiz◦ Close Reading: Why are veins blue?◦ Notes: Composition of Blood◦ Closing
Homework:◦ Write two questions you have about blood or the
cardiovascular system on a half sheet of paper◦ Find out your blood type! (ask your parents)
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Endocrine System QuizPut everything away except for a
writing utensilIf you have a question during
your quiz, raise your hand and I will come answer it
Hold on to your quiz when you finish; I will collect them all at the same time
Good luck!
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Close Reading: Why do veins appear blue?Working individually, read and
answer the questions related to your reading, “Why do veins appear blue?”