vp.org cimit harvard
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www.VP.org
The New VP.org
Why VP.org?
Research = Re-Search!
• 1) Search for prior observations.
• 2) Make new observation.
Olcott 1931 “plaque rupture”
Leary 1934 “rupture of atheromatous abscess”
Wartman 1938 “rupture-induced occlusion”
Horn 1940 “plaque fissure”
Helpern 1957 “plaque erosion”
Crawford 1961 “plaque thrombosis”
Gore 1963 “plaque ulceration”
Friedman 1964 “macrophage accumulation”
Byers 1964 “thrombogenic gruel”
Chapman 1966 “plaque rupture”
Plaque Fissure in Human Coronary Thrombosis (Abstract) Fed. Proc. 1964, 23, 443 Constantinidis P.
“The destruction of the hyalinized wall separating lumen from the atheroma was almost always observed to be preceded by or associated with its invasion by lipid containing macrophages.” Friedman and van den Bovenkamp 1965
Recycling of Science and Missed Opportunities to Save Lives• If plaque rupture was broadly communicated between all investigators and
clinicians involved in the field of cardiovascular disease, in other words, if cardiovascular pathologists, clinicians, and biologists in 1960s perhaps:
– Thermal detection could have been in clinical trial in 1970s. We could not have OCT which needs fast computer processing but NIR spectroscopy could have been a possibility as they were screening lean meet from fat in food industry in 1970s
– Plaque immunology could have been fully investigated by 1980 and specific immune markers of plaque inflammation might have been available as a cheap bedside test to all primary care physicians in 2001.
– …
– Millions of lives including our grand parents and parents, friends and relatives could have been saved to enjoy a few more years with their families...
Internet
• No need to talk about.
Visit:EverythingYouWant.Com!
Re-Search @ the Speed of Light
Mort Gates!!!
What’s new in VP.org?
• Medical Professional (VP Community and others)
• Industry• Media• Consumers (patients and their relatives) ACC 2002
• VP Biology and Pathology• VP Detection• VP Treatment
What’s new in VP.org?
• “Atheroline”; A new online library powered by: Medline, Science Citation Index, patent data bases (United States, and PCT), multimedia presentations, conference abstracts, and regular update of clinical trials along with many novel interactive features, all dedicated to the field of Atherosclerosis and investigators in the field of vulnerable plaque.
What’s new in VP.org?
• “Atheroline Toolbar” a truly one-click-away option to the whole world of medical literature and online information related to atherosclerosis and vulnerable plaque
What’s new in VP.org?
• “Personal VP Watch” members of VP.org can program their own VP Watch to receive individualized VPW (science, patents, industry…) on any periodical basis, daily, twice a week, weekly, bi-weekly…
Dear VP Scientist and Industry:
Rest assured and sleep well as I am up 24 hr 7 days a week / 365 days watching VP for you.
Looking forward to seeing you at the VP Dinner Symposium in Anaheim, California Monday November 12, 7-10pm @ the Hilton Convention Center.
May God bless your heart with no VP.
Sincerely yours!VP Watch
The New VP.org is coming up in 36 days.
COUNT DOWN!
8pm
Monday November 12th – Vulnerable Plaque Dinner Symposium
The Hilton @ Convention Center
AHA 2001 Anaheim, California
Please tell your Palm Pilot
Mohammad Madjid, MD
Reza Mohammadi, MD Parsa Mirhaji, M.D.
Mohammed Reza Khan, MD
Khawar Gul, M.D.
New Members of VP.org Team
• Eric Jarvis• Alireza Zarrabi• Cornelius Nwora• Shayda Katousian• Mark Johnson• Marilyn Sanders
2001 2050
Genomic
Proteomic
2010 2020 2030 2040
Celomic?
VP Treatment
Home-based VP Screening Test
Heart Attack
Eradicated
US Annual MI
<50,000
Heart Cloning
VP Rx as OTC or Vaccine?
Eradication of Heart Attack
VP Detection
Mission Impossible!
Association for Eradication of Heart Attack
www.VP.orgwww.AEHA.org