7/24/2019 Vivapur Mcc Spheres Gb 1009

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Chemically Inert Carrier for

Multi-particulate Formulation Applications

Compatible with Soluble and Insoluble APIs

Permits Dissolution Profile Flexibility

Adaptable to High and Low Dose Loading

Microcrystalline Cellulose Pellets

Ph.Eur., NF, JP

VIVA MCC SPHERESPUR

7/24/2019 Vivapur Mcc Spheres Gb 1009

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VIVA MCC SPHERESPUR

General Information

Spheres become more important in today s formulation

development strategy. When multiple API or controlled

release doses are preferred,

provide benefit.

are extremely robust. They consist

purely of Microcrystalline Cellulose (Ph.Eur., NF, JP) which

makes them the preferred, chemically inert carrier

For formulation application, can

be used as API carriers. The coated spheres can be filled

into capsules or compacted into tablets.

VIVAPUR MCC SPHERES

VIVAPUR MCC SPHERES

VIVAPUR MCC SPHERES

Compatible with soluble and insoluble APIs

Permits dissolution profile flexibility

Adaptable to high and low dose loading

Microcrystalline Cellulose Pellets

VIVA MCC SPHERESPURIV PUR M SPHERES

Product Portfolio

VIVAPUR MCC SPHERES m mesh

Grade 100 100 - 200 70 - 140

Grade 200 200 - 350 45 - 60

Grade 350 350 - 500 35 - 45

Grade 500 500 - 710 25 - 35

Grade 710 710 - 1000 18 - 25

Tab. 1

Appearance nearly white round shaped spheres

Taste / Odor tasteless, odorless

Solubility insoluble in water and most organic solvents

Bulk Density 800 g/lSphericity 0.9 0.05

Friability < 0,1 %

Loss on Drying 7.0 %

Swelling Index < 2