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INNOVATION EDUCATION EVIDENCE Consensus Update Vascular & Endovascular 25–28 APRIL 2017 OLYMPIA GRAND • LONDON • UNITED KINGDOM CX Symposium [email protected] @cxsymposium Second Announcement Peripheral Arterial Consensus Aortic Consensus Acute Stroke Consensus Venous Consensus CHALLENGES CONTROVERSIES CONSENSUS

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INNOVATIONEDUCATION EVIDENCE

Consensus UpdateVascular & Endovascular

25–28 APRIL 2017OLYMPIA GRAND • LONDON • UNITED KINGDOM

CX Symposium [email protected] @cxsymposium

Second Announcement

PeripheralArterial

Consensus

AorticConsensus

AcuteStroke

Consensus

VenousConsensus

CHALLENGESCONTROVERSIES CONSENSUS

Vascular & Endovascular Consensus Update 2017

2

Aortic

Andrew Holden

Associate Professor of Radiology at Auckland University School of Medicine and Director of Interventional Services at Auckland City Hospital, Auckland, New Zealand

Janet Powell

Professor of Vascular Biology and Medicine, Imperial College London, London, UK

Dittmar Böckler

Professor of Vascular Surgery at University of Heidelberg and Head of Department of Vascular Surgery and Endovascular Surgery at University Hospital Heidelberg, Heidelberg, Germany

Giovanni Torsello

Professor, Head of Department of Vascular Surgery at Franziskus Hospital and Director of the Clinic for Vascular and Endovascular Surgery at the University of Münster, Münster, Germany

Stéphan Haulon

Professor of Vascular Surgery, University of Lille, and Head of Vascular Surgery, University Hospital, Lille, France

Tilo Kölbel

Professor of Vascular Surgery, University of Hamburg, and Vascular Surgeon at the University Heart Center Hamburg, Hamburg, Germany

CX Programme Organising Board

Peripheral Arterial

Cliff Shearman

Professor of Vascular Surgery at University of Southampton and Vascular Surgeon in the Department of Vascular Surgery, University Hospital Southampton Foundation Trust, Southampton, UK

Michael Edmonds

Professor of Diabetic Foot Medicine and Consultant Diabetologist at King’s College Hospital, London, UK

Thomas Zeller

Professor of Angiology at Albert-Ludwigs University of Freiburg and Head of Department of Angiology at Universitäts – Herzzentrum Freiburg, Bad Krozingen, Germany

Iris Baumgartner

Professor and Head of Clinical and Interventional Angiology and Director of Vascular Research at University Hospital Bern, Bern, Switzerland

Andrew Holden

Associate Professor of Radiology at Auckland University School of Medicine and Director of Interventional Services at Auckland City Hospital, Auckland, New Zealand

Andrew Bradbury

Sampson Gamgee Professor of Vascular Surgery in the College of Medical and Dental Sciences at the University of Birmingham, UK, and Consultant Vascular and Endovascular Surgeon at the Heart of England NHS Foundation Trust in Birmingham, UK

Trevor Cleveland

Consultant Vascular Radiologist and Honorary Senior Lecturer at Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK

Frank Vermassen

Professor in Vascular and Thoracic Surgery Department of Vascular Surgery at Ghent University Hospital, Ghent, Belgium

International AdvisorsEric ChemlaEric VerhoevenGunnar TepeJan Brunkwall Krassi IvancevPatrick PeetersNick Cheshire

CX Abstract BoardIan Loftus, Co-chairmanRichard Gibbs, Co-chairmanPaul HayesRobert HinchliffeColin BicknellDaryll BakerRachel BellMarcus BrooksMeryl DavisSimon Ashley

Venous

Ian Franklin

Consultant Vascular Surgeon at London Vascular Clinic, London, UK

Stephen Black

Consultant Vascular Surgeon at Guy’s and St Thomas’ Hospital, London, UK

Alun Davies

Professor of Vascular Surgery at Imperial College London and Consultant General Surgeon at Charing Cross Hospital, London, UK

Andrew Bradbury

Sampson Gamgee Professor of Vascular Surgery in the College of Medical and Dental Sciences at the University of Birmingham, UK, and Consultant Vascular and Endovascular Surgeon at the Heart of England NHS Foundation Trust in Birmingham, UK

Acute Stroke

Ross Naylor

Honorary Professor of Vascular Surgery at University of Leicester and Consultant Vascular Surgeon at Leicester Royal Infirmary, Leicester, UK

Martin Brown

Professor of Stroke Medicine, Stroke Research Centre, UCL Institute of Neurology and Consultant Neurologist, The National Hospital for Neurology & Neurosurgery, Queen Square, London, UK

Chairman

Roger Greenhalgh

Emeritus Professor of Surgery and Head of Vascular Surgery Research Group at Imperial College London, London, UK

Co-chairmen

Frans Moll

Professor of Vascular Surgery at University Medical Center Utrecht, Utrecht, Netherlands

Matt Thompson

Professor of Vascular Surgery at St George’s University of London and Consultant Vascular Surgeon at St George’s Vascular Institute, London, UK

2017 Vascular & Endovascular Consensus Update

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FacultyCX Invited Faculty will include:

Gary AnselRuth BensonColin BicknellMartin BjörckStephen BlackDittmar BöcklerAndrew BradburyMarianne BrodmannMartin BrownYiu-Che ChanTrevor ClevelandFrank CriadoMartin CzernyFabrizio D’AbateMichael DakeJosefin DammHector de BeaufortRick de GraafSebastian DebusJonothan Earnshaw

Hans-Henning EcksteinFabrizio FanelliMark FarberIan FranklinPeter GainesMauro GargiuloPhilipp GeisbueschRichard GibbsKathleen GibsonManj GohelWilliam GrayFranco GregoMo HamadyGeorge HamiltonStéphan HaulonClaudine Hemel-DesnosRobert HinchliffeAndrew HoldenPeter HoltDominic Howard

Nicholas InstonMichael JaffArkadius JawienMuholan KanapathyAlan KarthikesalingamNarayan KarunanithyNarendra Nath KhannaTilo KölbelNils KucherMichael LichtenbergFrancesco LiistroIan LoftusLars LönnKevin ManiSahar MansourHugh MarkusTara MastracciCharles McCollumVicky McDonaldRichard McWilliams

Marc MeissnerMatthew MenardRoss MilnerBijan ModaraiRobert MorganGiovanni MostiErin MurphyPatrice MwipatayiAndrew NicolaidesKatariina NorenenPasha NormahaniIsaac NyamekyeGustavo OderichGerard O’SullivanKeith PoskittJohann Christof RaggVenkatesh RamaiahAlbert-Adrien RameletMichel ReijnenTimothy Resch

Robert RheeVincent RiambauCelia RigaFiona RohlffsHervé RousseauDavid RussellRichard SaxonDierk ScheinertDarren SchneiderJulian ScottEva SevickCliff ShearmanMalcolm SimmsIan SparkMichael SweetingOmke TeebkenGunnar TepeFabien ThaveauMatt ThompsonGiovanni Torsello

Domenico ValentiJos van den BergJoost van HerwaardenMarc van SambeekSuresh VedanthamFrank VeithMaarit VenermoHence VerhagenEric VerhoevenFrank VermassenFabio VerziniAnders WanhainenRodney WhiteDean WilliamsThomas ZellerSebastian ZerwesWei Zhou

3 days of Aortic Consensus Update

Day 1 – CX Aortic Edited Cases Day 2 – Abdominal Aortic Main ProgrammeDay 3 – Thoracic Aortic Main Programme

3 days of Peripheral Arterial Consensus Update

Day 1 – Peripheral Arterial Main Programme Day 2 – CX Live and Edited Peripheral Cases Day 3 – CX ilegx Interdisciplinary Consensus on Severe Ischaemia

3 days of Venous Consensus Update

Day 1 – Venous Main ProgrammeDays 2 and 3 – CX Venous WorkshopThe CX Venous Workshop will be held on Ground Floor, adjacent to the Exhibition Hall.

NEW Venous edited casesFor the first time, edited cases on venous intervention will be presented at the CX Venous Workshop (Days 2 and 3), from 9.00 to 10.00. From 10.00 to 16.00 the workshop will continue with one-to-one, hands-on demonstrations.

Hands-on experienceDelegates will have the opportunity to participate in enhanced practical courses. Both the CX Venous Workshop and the CX Vascular Access Course provide stations for hands-on experience and interaction with experts.

Acute Stroke Consensus UpdateOn Day 4, the Acute Stroke Consensus Update will explore the relationship between aortic arch manipulation and stroke, and discuss new techniques for acute stroke intervention. It will also seek a vertebral and carotid consensus.

What to expect in 2017

Vascular & Endovascular Consensus Update 2017

4

CX 2017 Main Programme Highlights

Peripheral Arterial Consensus Update, including:

Acute ischaemia • Mechanical thrombectomy and thrombolysis

Internal iliac artery • When to deploy an iliac branched device

• Iliac aneurysm repair – the relevance of the second side

Superficial femoral artery• Vessel preparation before drug-coated balloon use

• Current guidelines for drug-coated balloons

• Stents: The value of biometric design and the value of radial strength

• New trial results: Comparison of two drug-eluting stents and comparison of drug-eluting stent vs. drug-coated balloon

Below the knee• “Endovascular first practice” may alter equipoise for below-the-knee trials

• Differences following open and endovascular management of critical

ischaemia using fluorescence imaging

Diabetic foot• Point-of-care duplex ultrasound: A paradigm shift in the detection of peripheral

arterial disease in diabetes?

• Microvascular complications of diabetes and implications to cardiovascular risk

Lifestyle• Exercise

• Smoking cessation

Pathways of CareThis year CX completes another cycle of Controversies, Challenges and Consensus. CX 2017 will continue to focus on

EDUCATION, INNOVATION and EVIDENCE in order to reach consensus in all aspects of vascular disease management. In all

sessions CX will address “Pathways of Care”, and the audience will hear presentations in all of the vascular domains on:

WHETHER to intervene and benefit from it

WHEN to intervene and at what threshold

INTERVENTION METHOD and evidence

FOLLOW-UP and outcomes of intervention

Abdominal Aortic Challenges Update, including:

Screening & indications• Cardiopulmonary exercise testing predicts perioperative mortality and long-

term survival in AAA patients

• Optimal management of men with small and medium AAA in surveillance

• Cardiac rehabilitation to improve life expectancy after AAA repair

Threshold• Operating below AAA threshold of 5.5cm saves lives – oh, yes? Let us listen

to the evidence

Method• The consequences of performing fewer open AAA repairs

• Reducing errors during minimally invasive procedures for elective AAA repair

• First clinical experience proves that new endografts overcome the current limitation in treating challenging neck

• Competence in EVAR techniques

• Safety considerations with hostile neck 10–15mm

2017 Vascular & Endovascular Consensus Update

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Outcomes and follow-up• Elective AAA repair – UK hospital data support the EVAR trial results

• CX Debate on annual imaging

• Constant checks for type I endoleak and migration

• Embolisation for type I endoleaks after EVAR? – Mid-term outcomes, pitfalls and patient selection

• Fabric degeneration and type III endoleaks remain a problem

Mini-symposium on type II endoleaks • Validation of a method to define patients at risk for type II endoleak, based on

preoperative CT anatomic characteristics

• What is the transiliac route for the embolisation of type II endoleaks post EVAR? – Technique, when to attempt it and efficacy

• Systematic review on treatment success for type II endoleak

• Direct percutaneous sac puncture an easy way to solve type II endoleaks after EVAR

Ruptured aneursyms• EVAR simulation for rAAA saves lives

• Ruptured AAA – the early benefit of EVAR is maintained out to six years, but overall survival remains poor

• Challenging anatomy predicts short- and long-term mortality and complications after rEVAR

• Challenging anatomy predicts mortality and complications after EVAR for ruptured AAA

• How involvement in the IMPROVE trial has altered practice and departmental consensus for open vs. endovascular strategies for repair of ruptured AAA

• Endovascular aortic repair out of instructions for use in ruptured AAA

Thoracic Aortic Challenges Update, including:• Thoracic pathologies and different approaches for each

• Total endovascular aortic repair

Ascending aortic aneurysm• Ascending aortic aneurysm remodelling for various pathologies

Arch aneurysm• CX Debate: Branched or fenestrated devices have superceded arch repair as

first-line treatment

• Long-term feasibility data of thoracic single branched endograft in the aortic arch zones 0, 1 and 2

• Anatomical challenges and TEVAR performance in the aortic arch

Risk of cerebral embolisation after arch procedures:

• The role of air embolisation in EVAR and TEVAR and strategies to prevent it

• The use of embolic filters to reduce the stroke risk in TEVAR

• Gaseous embolisation from the arch

Descending aortic aneurysm• CX Debate: Types A and B terms are no longer satisfactory

• Inflammatory aneurysm – current consensus guidelines do not apply with connective tissue disorders

• Migration after TEVAR

• Uncomplicated chronic type B dissection revisited

Juxtarenal• ESVS consensus guidelines for descending thoracic aorta management

• The ESVS Guidelines on the management of diseases of the mesenteric arteries and veins

• Treatment of complex aortic pathologies using parallel grafts, snorkels and

chimney grafts

Radiation dose awareness in aortic interventions• Total contrast-free EVAR: dream or reality?

• Contrast-enhanced cone beam CT for intraoperative quality assessment during endovascular aortic procedures

• Radiation exposure to operative teams – the need to reduce radiation dose in follow-up

• Cellular markers of radiation damage during TEVAR

• The use of IVUS to reduce radiation

Vascular & Endovascular Consensus Update 2017

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Venous Consensus Update, including:

Investigations of superficial and deep venous anatomy• The search for the best imaging modality is a worldwide problem

• CT venography and MR venography are performed in the horizontal position – Suitability for assessing venous function

• The place of ultrasound for deep venous assessment

• Value of intravascular ultrasound in venous investigation and radiation reduction

Assessment and interventions of acute and established superficial and deep venous thrombosis• Pathways of care for venous stenting interventions

• Treatment for acute deep venous thrombosis – Pathways of care on the use of catheter-directed thrombolysis and mechanical thrombectomy

• ATTRACT trial: Medical treatment versus intervention (catheter-directed thrombolysis or mechanical thrombectomy)

• Surveillance of venous stents

Pelvic vein congestion and reflux• Prevalence of venous reflux de novo

• Distinguishing pathological from natural reflux

Varicose vein management • Percutaneous valvuloplasty

• Biomatrix sclerofoam as a rival for endothermal ablation

• Predictors of recanalisation after acrylocyanate truncal vein treatment

• Improved compression techniques

• PressPatch device to improve working compression pressure

Aesthetic phlebology• Optimising cosmetic outcomes for reticular veins and telangiectasis

• Foam sclerotherapy for reticular veins and telangiectasis

Lymphoedema• Modern understanding of primary lymphatic dysplasias and prognosis

• Modern strategies for imaging in lymphoedema

• Surgical procedures for lymphoedema

Leg ulceration• Modern guidelines for leg ulceration

• Pathways of care – Early Venous Reflux Ablation (EVRA)

Upper limb/subclavian vein compression• Conservative treatment of Paget Schrötter syndrome

• Treatment of subclavian vein compression/central veins occlusions

Acute Stroke Update, including:

Carotid endarterectomy• The decreasing numbers of patients undergoing CEA – is it risk aversion or

better medical management?

• Predicting stroke risk in carotid disease duplex ultrasound criteria including carotid plaque volume

• What is wrong with current carotid guidelines and why guidelines are misleading

Vertebral artery intervention• Rapid interventions are essential (VIST and VAST trials)

• Sex and age affects the outcomes of carotid endarterectomy and carotid artery stenting

• The need for co-ordination of services

Intracranial intervention• Cerebral micro-embolisation during endovascular aortic surgery – The case

for investigating the benefits of carotid protection devices in all endovascular patients, and the need for a consensus on protocols

• Protocol for patient with stroke after an endovascular aortic arch procedure

• What the HERMES collaboration tells us about structuring systems of care to provide timely treatment to acute ischaemic stroke patients

• Aortic arch endovascular procedures and location of stroke care

• The European experience with mobile stroke units

• The role of emergency medical service providers in improving stroke pathways of care

• MR, CT angiography or CT perfusion – which imaging is best?

• General anaesthesia versus conscious sedation

• Stent retriever, aspiration, or both

• New thrombectomy technology

• Ongoing and upcoming trials

2017 Vascular & Endovascular Consensus Update

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Step 1: Visit www.cxsymposium.com to complete online or

to download printable registration/hotel forms.

Step 2: Choose your registration rate.

Step 3: Make your payment.

Step 4: We will send you confirmation of your registration within 48hrs.

Step 5: Visit www.cxsymposium.com/cxhotels to book your hotel.

Step 6: We will send you an email with your unique barcode 10 days before the event for badge collection.

Terms

* Early bird rates are valid for registrations received before midnight on 26th February 2017.

** Late/onsite registration applies after Friday 21st April 2017.

• Rates are inclusive of VAT at 20%. • Credit card payments received via mail or

telephone will be processed in GBP and debited at the current rate of exchange.

• Cancellation policy: Cancellation prior to 24th March 2017 will be subject to a 20% administration charge. We regret that refunds after this date will not be available.

• Junior doctors should provide letter of authorisation.

• Registrations will not be confirmed unless we receive the full contact details of the delegate, including the direct email address.

• Industry participants should register at the full registration rate.

• All registrations except the CX Vascular Access 3-day course allow entry to all main and parallel events.

CX 4-DAY RATE CX 1-DAY RATE

Early bird* Standard rate Late/onsite registration** Early bird* Standard rate Late/onsite registration**

Full registration £695 £795 £895 £295 £345 £385Junior doctor registration £345 £395 £445 £150 £180 £195Vascular technologist/nurse £145 £175 £195 £75 £95 £105

Note: Includes symposium book Note: Excludes symposium book

CX VASCULAR ACCESS 3-DAY COURSE CX ACUTE STROKE CONSENSUS – FRIDAY

Early bird* Standard rate Late/onsite registration** Early bird* Standard rate Late/onsite registration**

Doctor rate £295 £350 £395 £95 £115 £125Nurse rate £75 £95 £105

Note: Includes CX Vascular Access activities on the Wednesday, Thursday & Friday only. Excludes entry to other CX events and symposium book Note: Friday only. Excludes delegate bag and symposium book

CX Parallel SessionsThe Parallel Sessions of the Charing Cross Symposium offer attendees the opportunity to enhance skills for daily clinical practice in the vascular and endovascular field with educational and practical sessions.

CX Aortic Edited Cases •CX Peripheral Live and Edited Cases •CX Venous Workshop •CX Vascular Access Course

CX Abstract and Poster Sessions ••••CX ilegx Interdisciplinary Consensus on Severe Ischaemia •CX Innovation Showcase ••••CX Meets Latin America ••CX Paediatric Issues and Congenital Vascular Malformations

LINC@CX •

How to register for CX 2017

CX missionThe Charing Cross Symposium raises vascular and endovascular controversies so that a world-class faculty challenges the available evidence in order to reach a consensus after discussion with an expert audience. This forms a three-year cycle – in 2017, the CX programme is designed to reach consensus after discussion.

CX programme and formatAll Charing Cross Symposia are distinguished by a unique and logical programme, which focuses on identifying evidence for optimal vascular disease management from head to toe, catering for all vascular specialists.

Debate and emphasis on interaction with an expert audience are key aspects of the CX style. Education, Innovation and Evidence are CX core values.

Short presentations and time-keeping are key characteristics of the CX sessions; these enable the right time for comments and questions by the audience.

At the sessions, there is a chairman who monitors time, encourages audience and speaker interaction and conducts the discussion; there is also a moderator who assists the chair with questions to and from the audience.

EDUCATION INNOVATION EVIDENCE

General enquiries

Charing Cross Symposium

526 Fulham Road,

London SW6 5NR, United Kingdom

Tel: +44 (0) 20 7736 8788

Fax: +44 (0) 20 7736 8283

Email: [email protected]

Exhibitor information

Shilpa Suthar

Tel: +44 (0) 20 7736 8788

Fax: +44 (0) 20 7736 8283

Email: [email protected]

Key dates

Early bird registration ends: 26 February 2017Save the CX 2017 dates: 25–28 April 2017