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Utrecht Summer School course Infection meets Immunity July 30 – August 10, 2012 Infection & Immunity Center Utrecht Heidelberglaan 100 – H03.314 Tel: 088 75 50486 E-mail: [email protected]

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Page 1: Utrecht Summer School course Infection meets Immunity Programma 2012.pdf · 2013-04-13 · Utrecht Summer School course Infection meets Immunity July 30 – August 10, ... 12.15 Phagocytes

Utrecht Summer School course

Infection meets Immunity

July 30 – August 10, 2012

Infection & Immunity Center Utrecht Heidelberglaan 100 – H03.314 Tel: 088 75 50486 E-mail: [email protected]

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Infection meets Immunity

Contents General information ................................................................................................................. 3 Programme ............................................................................................................................... 5 Speaker contact information.................................................................................................. 15 Route description UMC Utrecht ............................................................................................. 17 Route description venues ....................................................................................................... 18

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Infection meets Immunity

General information

Target group The program is intended for master students and starting PhD-students. It is necessary to have a course certificate in Immunology and/or Microbiology or courses with similar content.

Course aim Utrecht University has a strong history in research Infection and Immunity. It is home to some world-wide expert research teams in this area. The aim of this course is to familiarize you in depth with the scientific knowledge in the field of Infection and Immunity. After this course students will be able to relate immunological principles and clinical consequences and will have knowledge about bacterial and viral related diseases. Especially on those areas where infection meets immunity

Reading

Immunology: Kuby et al. 6th edition, 2006, W.H. Freeman & Company

Alberts - Molecular Biology of the Cell, 4th or 5th edition

Schaechter’s Mechanisms of Microbial Disease Webinars http://hstalks.com/main/index_category.php?id=252 http://www.roitt.com/podcastlist.asp http://www.jacionline.org/content/podcast http://www.sg.uu.nl/publicaties/podcasts/ http://www.materialise.com/webinarseries http://www.jimmyr.com/blog/1_Top_10_Universities_With_Free_Courses_Online.php

Feedback We value your opinion and try to improve our course every year. In your binder you will find an evaluation form. Please fill out this form during the course.

Breaks The Infection & Immunity Center Utrecht will provide you with coffee and tea during the coffee breaks. The University Hospital (UMC Utrecht) will provide you with a lunch card. You can use this card in the staff canteen at the UMC Utrecht.

Internet access The “studielandschap” (2nd and 3rd floors of the Hijmans vd Bergh) has public computers. You should be able to access through wireless too in the Hijmans van den Bergh building and the foyer of the University Hospital. Information on wireless can be found here: www.studielandschap.nl Most of the information is in

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Infection meets Immunity

Dutch, but the part about wireless has an English version.

Also, the University Library has computers and wireless access.

Secretary Karlijn Visser UMC Utrecht, room H03.314 Phone: +31 (0)88 755 0486, email: [email protected]

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Infection meets Immunity

Monday 30 July 2012

Venue: Hijmans vd Bergh building, room 2.05 Registration 9.30 – 10.30 International Office, UMC Utrecht Introduction 10.30 – 12.30 Microbiology Jos van Putten 12.30 - 13.30 Lunch provided by Infection and Immunity Center Utrecht 13.30 - 15.30 Immunology Frits Gmelig Meyling 18.00 Utrecht Summer School: Scavenger hunt Utrecht & Welcome dinner

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Infection meets Immunity

Tuesday 31 July 2012

Venue: Hijmans vd Bergh building, room 2.05 Tumor Immunology 09.00 - 10.30 Tumor immune surveillance and Immune escape Niels Bovenschen

10.30 – 12.00 Dedicated animal models for tumor immunotherapy Anton Martens 12.00 - 13.00 Lunch Break 13.00 – 14.30 Tumor immunotherapy with innate immune cells Jurgen Kuball 14.30 - 16.00 Tumor immunotherapy with allo-SCT and donor T cells Tuna Mutis 17.00 – 18.30 Welcome UMC Utrecht Meeting Point: International Office!!!! 21.00 hrs Utrecht Summer School: drinks

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Infection meets Immunity

Wednesday 1 August 2012

Venue: Hijmans vd Bergh building, room 2.05 Bacterial Pathogenesis: The case of Staphylococcus aureus 09.00 - 9.15 Intro Jos van Strijp 9.15 - 10.45 Complement and complement evasion Suzan Rooijakkers 10.45 - 11.00 Break 11.00 - 12.15 Phagocytes and Phagocytosis Evasion Kok van Kessel 12.15 - 13.15 Lunch Break 13.15 - 14.45 Interactive Session: Bacterial evasion strategies Carla de Haas

and Jovanka Bestebroer

14.45 - 16.15 Interactive Session: Quorum Sensing, Intracellular Reindert Nijland and Survival and Biofilms and Jos van Strijp 16.15 - 16.30 Closing Remarks Jos van Strijp 18.30 Traditional (indoor) picnic

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Infection meets Immunity

Thursday 2 August 2012

Venue: Hijmans vd Bergh building, room 2.05

The tolerant Immune System 09.00 – 10. What is tolerance? Willem van Eden 09.10 - 10.30 How the antigen processing pathway regulates CD8 Alice Sijts

T cell responses to self and foreign antigens 10.30 – 11.00 Break 11.00 - 12.30 Utilizing regulatory T cells to fight autoimmune diseases Martijn van Herwijnen 12.30 - 13.30 Lunch break Dead by immunity: Sepsis 13.30 – 17.00 Interactive session Eric Hack 19.30 Night Canoeing

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Infection meets Immunity

Friday 3 August 2012

Venue: Hijmans vd Bergh building, room 2.05

Extracellular Microbiology 09.00 - 10.30 Bacterial virulence strategies Jos van Putten 10.30 - 11.00 Break 11.00 - 12.00 The Campylobacter problem Lieneke Bouwman Saturday 4 August, 10.00 Discover Holland Day Sunday 5 August, 9.30 Visit to Rotterdam & Delft

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Infection meets Immunity

Monday 6 August 2012

Venue: Hijmans vd Bergh building, room 2.05 09.00 - 10.30 Autoimmunity Ruth Fritsch 10.30 - 11.00 Break 11.00 - 12.00 Allergy; the clinical point of view Carla Bruijnzeel-Koomen 12.00 - 13.00 Is IgE all there is in allergy? Edward Knol 13.00 - 14.00 Lunch Break 14.00 - 17.00 Hygiene hypothesis; infection meets allergy? Edward Knol

21.00 Utrecht Summer School: Pub Quiz & Summerschool drinks

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Tuesday 7 August 2012

Venue: Hijmans vd Bergh building, room 2.05

Clinical and veterinary bacteriology: diagnostics and public health

9.00 – 9.15 Introduction and explanation of today’s program Hans Kusters 9.15 – 10.15 Antibiotic resistance: Apocalyps now or media hype? Marc Bonten 10.15 – 10.45 Break 10.45 – 11.35 Healthy feed – healthy animals – healthy food Boyd Berends 11.35 – 12.30 Antimicrobial: the more we use, the faster we lose Els Broens 12.30 – 13.30 Lunch Break 13.30 – 14.30 Molecular epidemiology and population genetics in Rob Willems infectious diseases 14.30 – 15.15 Clonal emergence of staphylococcus pseudintermedius Koen Verstappen among the Dutch dog population 15.15 – 15.30 Break 15.30 – 16.30 Clinical microbiological diagnostics Hans Kusters

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Wednesday 8 August 2012

Venue: Hijmans vd Bergh building, room 2.05 Vaccines 09.00 - 09.30 Introduction Victor Rutten 09.30 - 10.15 Vaccines: from trial and error to rational design Claire Boog

10.15 - 10.45 Break 10.45 - 11.30 Pneumococcal Vaccination Lieke Sanders 11.30 - 12.15 Vaccination against mycobacterial infections Victor Rutten 12.15 - 13.00 Contribution from Veterinary Medicine 13.00 - 14.00 Lunch break 14.00 - 16.00 Guided tour Faculty of

veterinary Medicine !Venue: Androclusgebouw (Androclus building), Yalelaan 1, De Uithof, Utrecht! Meeting point at the entrance of the Building

18.00 Utrecht Summer School: Traditional Dutch Picnic

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Thursday 9 August 2012

Venue: Hijmans vd Bergh building, room 2.05 9.00 - 9.45 HIV entry; a key process in viral transmission, pathogenesis Anne Wensing

and eradication 9.45 - 10.30 Immune evasion by viruses: masters of disguise Emmanuel Wiertz 10.30 - 11.00 Break 11.00 -11.45 Evasion of innate and adaptive immunity by Epstein-Barr virus: Danielle Horst putting the puzzle together 13.00 - 15.00 Tour of the medical microbiology lab with demonstrations of various state-of-the art techniques 19.30 Utrecht Summer School: Night Canoeing

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Friday 10 August 2012

Venue: Hijmans vd Bergh building, room 2.05 09.00 - 09.30 International office present to collect your keys and lunch cards 09.30 - 12.30 “The great debate” 12.30 Certificates and evaluation

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Speaker contact information

Name Institute Email

Boyd Berends Veterninary Sciences Public Health

[email protected]

Jovanka Bestebroer UMC Utrecht Department of Microbiology

[email protected]

Marc Bonten UMC Utrecht Medical Microbiology

[email protected]

Claire Boog National Institute for Public Health and the Environment Unit Vaccinology

[email protected]

Lieneke Bouwman Veterinary Sciences Department of Infection Biology

[email protected]

Niels Bovenschen UMC Utrecht Department of Pathology

[email protected]

Els Broens Veterinary Sciences VDMC

[email protected]

Carla Bruijnzeel-Koomen

UMC Utrecht Department of Dermatology

[email protected]

Willem van Eden Veterinary Sciences Department of Immunology

[email protected]

Ruth Fritsch UMC Utrecht Department of Immunology

[email protected]

Frits Gmelig Meyling UMC Utrecht Department of Immunology

[email protected]

Carla de Haas UMC Utrecht Department of Microbiology

[email protected]

Erik Hack UMC Utrecht Department of Immunology

[email protected]

Martijn van Herwijnen Veterinary Sciences Department of Immunology

[email protected]

Daniëlle Horst UMC Utrecht Department of Microbiology

[email protected]

Kok van Kessel UMC Utrecht Department of Microbiology

[email protected]

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Edward Knol UMC Utrecht Department of Dermatology

[email protected]

Jurgen Kuball UMC Utrecht Department of Haematology

[email protected]

Hans Kusters UMC Utrecht Department of Microbiology

[email protected]

Anton Martens UMC Utrecht Department of Immunology

[email protected]

Tuna Mutis UMC Utrecht Department of Clinical Chemistry and Haematology

[email protected]

Reindert Nijland UMC Utrecht Department of Microbiology

[email protected]

Jos van Putten Veterinary Sciences Department of Infection Biology

[email protected]

Suzan Rooijakkers UMC Utrecht Department of Microbiology

[email protected]

Victor Rutten Veterinary Sciences Department of Immunology

[email protected]

Lieke Sanders UMC Utrecht Department of Immunology

[email protected]

Jos van Strijp UMC Utrecht Department of Microbiology

[email protected]

Alice Sijts Veterinary Sciences Department of Immunology

[email protected]

Koen Verstappen Veterinary Sciences Department of Infection Biology

[email protected]

Anne Wensing UMC Utrecht Department Microbiology

[email protected]

Emmanuel Wiertz UMC Utrecht Department of Microbiology

[email protected]

Rob Willems UMC Utrecht Department of Microbiology

[email protected]

Marc Wösten Veterinary Sciences Department of Infection Biology

[email protected]

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Route description UMC Utrecht Public transportation The UMC is well accessible by public transportation. From the central train station (Utrecht CS) busses 11 and 12 go to “the uithof” and the UMC Utrecht. For bus 12 the UMC is the last bus stop. Bus 11 stops at the UMC, but it is not the last stop.

Parking You can park your car at the parking space of the UMC Utrecht.

From Den Haag/Rotterdam: (A12) follow Utrecht. At the junction Lunette, go in the direction Amersfoort (A27). Follow the signs H UMC. After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated.

From Breda/Den Bosch (A27) or Arnhem (A12) At the junction Lunette, go in the direction Hilversum (A27) At the junction Rijnsweerd, go in the direction Amersfoort and directly leave the highway at exit “De Uithof / UMC” After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated.

From Amersfoort (A28) Follow Utrecht and leave the highway at exit “De Uithof / UMC” After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated.

From Hilversum (A27) At the junction Rijnsweerd, go in the direction Amersfoort and directly leave the highway at exit “De Uithof / UMC” After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated.

From Amsterdam (A1) Leave the A1 at exit Hilversum (A27). At the junction Rijnsweerd, go in the direction Amersfoort and directly leave the highway at exit “De Uithof / UMC” After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated.

From Amsterdam (A2) At the junction Oudenrijn go in the direction Arnhem (A12). Follow the A27 in the direction Amersfoort. At the junction Rijnsweerd, go in the direction Amersfoort and directly leave the highway at exit “De Uithof / UMC” After you have left the highway, turn left at the traffic lights. From there, the university hospital is indicated.

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Route description venues Hijmans van den Bergh building Room HB 2.05

Start: main entrance UMC Utrecht o Go to the left and walk until you reach the red junction. o Go to the left, you are now entering the Hijmans van den Bergh building. o There is an elevator on your right, take the elevator to the 2nd floor. o When you exit the elevator, go left. o Room HB 2.05 is the room in front of you. Wilhelmina Children’s Hospital (WKZ) Kindertheater (Children’s theatre)

Start: main entrance UMC Utrecht o Walk straight until you can’t go any further (you’ll see 2 elevators in front of you and a

glass door on your right). o Take the elevator to floor -1. o When you exit the elevator, go into the tunnel on your left. o Walk until you exit the tunnel o Go into the corridor on your left and walk until you reach the elevators and stairs. o Go to floor 0, you are now in the children’s hospital. o Cross the foyer and go into the corridor. o The children’s theatre is about halfway down the corridor, on the left. UMC Utrecht Computer room 2

Start: main entrance UMC Utrecht o Go to the left and walk until you reach a red door on your right. o Go through these doors and walk to the back of the room. o Go into the corridor on the right (follow the signs “CLZ2”) o Computer room 2 is the last room on the right.