using bizint smart charts with gene sequence databases · 2 sample sequence data report show a...

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1 Using BizInt Smart Charts with Gene Sequence Databases BizInt Smart Charts 2012 PIUG Biotech 2012 John Willmore, VP Product Development February 7, 2012 – Boston, MA BizInt Smart Charts software helps you create, customize and distribute tabular reports… … combining data from patents, drug pipeline, clinical trials, and gene sequence searches. BizInt Smart Charts 2012 Search results or alerts Easy-to-read summary table

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Page 1: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Using BizInt Smart Charts with Gene Sequence Databases

BizInt Smart Charts 2012

PIUG Biotech 2012John Willmore, VP Product DevelopmentFebruary 7, 2012 – Boston, MA

BizInt Smart Charts software helps you create, customize and distribute tabular reports…… combining data from patents, drug pipeline, clinical trials, and gene sequence searches.

BizInt Smart Charts 2012

Search results or alerts

Easy-to-read summary table

Page 2: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Sample sequence data report

Show a sample report with sequence data

Bibliographic Data

Sequence Data

BizInt Smart Charts 2012

Sequence Data

Query Results

P d b STN P B Mi P Patent databases: STN, PatBase, MicroPatent, Questel (QPAT, Qweb, Orbit), Delphion, IDdb, Integrity, Thomson Pharma IP, TotalPatent, Thomson Innovation

Non-patent literature databases: Embase

BizInt Smart Charts 2012

Non patent literature databases: Embase, Biosis, Medline, Chemical Abstracts, etc.

Page 3: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Gene sequence databases:

GenomeQuest: GQPAT, GeneSeq

STN: USGENE, DGENE, PCTGEN

Gene sequence databases:

BizInt Smart Charts 2012

Generating Sequence IDs from Source Data

Different ways to present Sequence ID

Combine sequence number and publication Combine sequence number and publication number to create Sequence IDs

Improves ability to find “duplicates” across databases and queries

TIP: Include AN in USGENE/PCTGEN

BizInt Smart Charts 2012

TIP: Include AN in USGENE/PCTGENInclude PSL and DESC in DGENE

Page 4: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Generating Sequence IDs from Source Data

BizInt Smart Charts 2012

Combining without removing duplicates

BizInt Smart Charts usually keeps only one copy of each record when combining chartscopy of each record when combining charts

A sequence may be retrieved by several queries, and you want to keep each result

New option to combine without removing duplicate records

BizInt Smart Charts 2012

p

Page 5: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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From February 2010 “Tips and Tricks”

Show alignment and query results

TIP: Select Alignment columnChange font to Courier New 8pt

BizInt Smart Charts 2012

Change font to Courier New 8pt

Better “Fixed Width” text handling for Alignment

New text property “Fixed Width”

Changes font to fixed width

Preserves spaces when exporting to HTML

BizInt Smart Charts 2012

Page 6: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Fixed Width Alignment in Microsoft Word

[show alignment in Word export]

[show export dialog, call out new exports]

[show new Optimized for Excel export]TIP: “fixed width” text doesn’t work well in the new Excel export

BizInt Smart Charts 2012

New Acrobat and Excel exports in Version 3.4

N t Fi d Width d ’t k ll i th

BizInt Smart Charts 2012

Note: Fixed Width doesn’t work well in the optimized export (we’re working on it)

Page 7: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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V i 1 0 l d i l 2011 Version 1.0 released in late 2011.

Information from related records is displayed in a single “Reference Row”.

A representative value is chosen from among all cells in a group

BizInt Smart Charts 2012

cells in a group.

Available as a separate utility working with patent, drug pipeline, and clinical trial reports.

Reference Rows: key features

BizInt Smart Charts 2012

Reference Row

Page 8: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Reference Rows: a sample patent report

A Reference Row summarizes related records from several sources.

BizInt Smart Charts 2012

Reference Rows: a sample patent report

Each representative cell in a Reference Row is selected from one

of the source documents.

BizInt Smart Charts 2012

Page 9: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Reference Rows: patent report

Smart Charts table corresponding to HTML.

The check marks indicated the selected cell in the software.

BizInt Smart Charts 2012

Reference Rows: patent report

Smart Charts table corresponding to HTML.

A cell is selected based on your ranking of the databases…

skipping empty cells until a value is found (as in Claims here).

BizInt Smart Charts 2012

( )

Page 10: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Reference Rows: patent report

Smart Charts table corresponding to HTML.

You can specify a more specific rule to select the reprentative cell,

including a database ranking just for

BizInt Smart Charts 2012

a particular column.

Reference Rows: patent report

Smart Charts table corresponding to HTML.

And you can always override the rules and select a specific cell.

BizInt Smart Charts 2012

Page 11: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Reference Rows: sequence report issues

Problem 1: This family has 48 sequence records

in the report!

Proposed solution: Group b d bli ti

BizInt Smart Charts 2012

based on publication or sequence ID

Reference Rows: sequence report issues

[show problem with sequence data]Problem 2: Selecting a

[call out for all sequences in a family grouped]

[call out for selecting representative % identetc.]

Problem 2: Selecting a representative value loses

meaningful information

BizInt Smart Charts 2012

Page 12: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Reference Rows: sequence report issues

P d S l ti 2 Proposed Solution 2: New rule to summarize

values in a Reference Row

BizInt Smart Charts 2012

Provides Vantage Point tools to normalize

Vantage Point –Smart Charts Edition

Provides Vantage Point tools to normalize and enhance BizInt Smart Charts reports.

Scheduled for release in mid 2012; many features are working now.

Combined with Reference Rows, helps

BizInt Smart Charts 2012

pyou create deduplicated & normalizedmulti-database reports.

Key is the XML Smart Data Exchange

Page 13: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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XML Smart Data Exchange

XML Smart Data Exchange

XML Smart Data Exchange

BizInt Smart Charts 2012

Enhance reports – normalize, filter & cluster

Filtered Assignees

Normalized names

BizInt Smart Charts 2012

Technology clusters

Page 14: Using BizInt Smart Charts with Gene Sequence Databases · 2 Sample sequence data report Show a sample report with sequence data Bibliographic Data Sequence Data BizInt Smart Charts

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Come to our tableto learn

!

TO LEARN MORE:

Visit our Table in the Exhibits Hall

Free Trial and documentation on our website

BizInt Smart Charts 2012

more! Free Trial and documentation on our websitewww.bizcharts.com

Webinars offered monthly