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03/11/2010 Bruker Confidential 1 17 th Bruker Users‘ Group Meeting 2010 Single Crystal X-ray Diffraction 21.09.2010 Karlsruhe Frank Burgäzy

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Page 1: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03/11/2010Bruker Confidential1

17th Bruker Users‘ Group Meeting 2010Single Crystal X-ray Diffraction

21.09.2010Karlsruhe

Frank Burgäzy

Page 2: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.2010Bruker Confidential2

50 Years Of InnovationBruker Corporation

Page 3: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.20103 Bruker Confidential3

The Beginnings

• Bruker was founded by Prof. Günther Laukien

• Professor for Experimental Physics

• First high-resolution systems for use in analytical chemistry in the US

• Recognized the power of NMR and the need for an impulse spectrometer

• Established BRUKER company in 1960

Prof. Günther Laukien

Page 4: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.20104 Bruker Confidential4

Why the Name Bruker ?

• At the time Bruker was founded, University professors in Germany were not allowed to commercialize their research while still teaching.

• Since Professor Laukien could not be named as a founding member, co-founder Dr. Emil Bruker provided his name to the growing start-up.

Page 5: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.20105 Bruker Confidential5

The Founding of Bruker-Physik AG

• Bruker Physik-AG was incorporated on September 7th, 1960

• Located in the backyard of a Karlsruhe residence

• Development of first NMR spectrometers began with the production of laboratory magnets and power supplies

• Bruker quickly outgrew this facility

• Moved to Rheinstetten

Bruker Physik AG’s first operational facility in Hardtstraße, Karlsruhe, Germany.

Page 6: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.20106 Bruker Confidential6

Trüb Täuber and Bruker in Switzerland

• 1960 - Trüb Täuber was developing NMR systems in Zürich

• Closely collaborating with the ETH Zürich

• First NMR, KIS, operated at 25 MHz using a permanent magnet

• KIS 2 introduced for high-resolution spectroscopy (90 MHz)

1962: NMR laboratory with with KIS1

Page 7: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.20107 Bruker Confidential7

Bruker-Spectrospin Collaboration

• Establishing Spectrospin AGenabled close cooperation with Bruker

• Introduction of first fully transistorized NMR instrument, the HFX 90

• First spectrometer to offer three independent channels for detection, decoupling, and lock

• New experiments became possible

• Previously difficult experiments became routine

1967: HFX 90, the first fully transistorized NMR system, equipped with three independent channels

Page 8: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.20108 Bruker Confidential8

Fourier Transform (FT) NMR

• 1964 - Fourier Transform research led to significant increases in sensitivity

• 1969 - World’s first FT-NMR spectrometer system that enabled broadband proton decoupling

• Sensational results including revolutionary 13C spectra

1971: WH 90, the first FT-only NMR Spectrometer1969 : One of the first 13C FT Spectra.

Measuring time now reduced to 200 seconds

Page 9: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.20109 Bruker Confidential9

Expansion towards North America

• 1968 - Bruker began delivering systems to America (Yale University)

• Systems were shipped by transatlantic air service

• To address growing American demand for these systems, Bruker opened its first US office in Elmsford, NY

1968: First HFX 90 for the United States (Yale Univ.) being loaded onto a Boeing 707

Page 10: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201010 Bruker Confidential10

The Global Bruker Group

• Increased global presence needed to become key player in the analytical instrument market

• Sales offices established throughout Europe, including UK and Italy in early 1970s

• 1969 - Expansion into USSR

• 1972 - Expansion reached Australia

• 1975 – Arrival in China, with a successful appearance at Exhibition in Beijing

1975: Mr. Fanf Yi, PRC Vice President and President of the Chinese Academy visits the Bruker stand at show in Beijing

Page 11: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201011 Bruker Confidential11

FT-IR

• Development of new infrared spectrometers in the 1970s

• 1974 - IFS 110 was Bruker’sfirst FT-IR spectrometer -the beginning of a very successful product line

• Foundation of the Bruker Optics division

• Today, Bruker Optics offers a comprehensive vibrationalspectroscopy product-line

1974: IFS 110, Bruker’s first FT-IR spectrometer

Page 12: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201012 Bruker Confidential12

Magnetic Resonance Imaging

• Strengths in NMR led to developments in MRI

• Late 1970s – Tomography systems for clinical and pre-clinical applications led to whole-body clinical MRI instrumentation

• Focus shifted towards pre-clinical systems

• Bruker BioSpin MRI today market leader in the field

1983: One of the first whole body MRI tomographs with air coil magnet

Page 13: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201013 Bruker Confidential13

Mass Spectrometry

• 1980 - Bruker founded “Bruker-Franzen Analytik”

• Adding quadrupole mass spectrometers to the Bruker portfolio

• Based on expertise in MR and superconducting magnet technology, Bruker successfully developed a new type of mass spectrometer

• 1982 - First installations of FT-ICR mass spec systems

• 1990 - Foundation of Bruker Saxonia in Leipzig, dedicated to ion mobility spectrometry

1980: MM1, the first mobile detection system

Page 14: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201014 Bruker Confidential14

X-ray Technologies

• 1997 - Bruker acquired the analytical X-ray division of Siemens AG

• Manufacturing facilities in Karlsruhe and Madison, Wisconsin

• Extended its technology portfolio by complementary business acquisitions (Nonius, MacScience, Röntec, PGT, Socabim, Keymaster, Quantron, JuWe, SIS, …)

• Today Bruker AXS is a global market and technology leader in materials research and quality control instrumentation for elemental and crystalline structure investigations

D8 ADVANCE, new generation of X-ray powder diffraction instrumentlaunched in 1997

Page 15: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201015 Bruker Confidential15

Superconductor Technologies

• Superconducting wire essential component of several product lines

• 2002 – Acquisition of Vacuumschmelze Hanau

• 2008 - Acquisition of ACCEL

• 2009 - Formation of Bruker Energy and Supercon Technologies (BEST)

• BEST is a leading manufacturer and developer of a broad range of high-performance superconductor wire products and devices Production of Bruker Energy & Supercon

Technologies in Hanau

Page 16: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201016 Bruker Confidential16

New Bruker Corporation

• 2000 - Organizational restructuringto meet the needs of modern markets

• 2001 - Bruker Daltonics was the first of to be listed on the NASDAQ, to be followed by Bruker AXS in 2002

• 2006 - Joined by Bruker Optics

• 2008 - Merger of all Bruker corporate units was complete, with the final addition of Bruker BioSpin, the magnetic resonance division that started it all

Bruker Corporation headquarters in Billerica, Massachusetts, USA

Page 17: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201017 Bruker Confidential

Bruker CorporationToday

• Bruker Corporation is one of the worldwide “top ten”analytical instruments companies with > $ 1 Billion 2008 revenue

• Bruker Corporation is listed at the NASDAQ (BRKR)

• More than 4500 employees worldwide

Page 18: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201018 Bruker Confidential

Bruker AXSWorldwide Sales & Service Locations

Headquarters and R&D and Production Centers

Technical Competence Centers

Sales and Service Offices

Page 19: Users‘ Group Meeting 2010 Single Crystal X-ray Diffractionxray.chem.wisc.edu/Resources/Meetings/Bruker18/01... · Superconductor Technologies • Superconducting wire essential

03.11.201019 Bruker Confidential

Bruker Corporation

FT-IRNMR

Raman

NIR

TD-NMR

MR Imaging

EPR ESI-TOF MS

FT-MS

ESI Ion Trap MS

MALDI-TOF MS

Bruker BioSpin Bruker DaltonicsBruker AXS Bruker Optics

XRFSC-XRD

XRD

Automation

MAOESAFM

Bruker EST

Synchrotron Instrumentation

Hydr. ExtrusionLow-Tc SCHigh-Tc SC

Magnets

PowerElectronicsTerahertz

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03.11.201020 Bruker Confidential20