uram ecp course

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Endoscopic CycloPhotocoagulation Martin Uram MD, MPH

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Page 1: Uram ecp course

Endoscopic CycloPhotocoagulation

Martin Uram MD, MPH

Page 2: Uram ecp course

Laser Endoscope

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 3: Uram ecp course

E2 Laser and Endoscopy System

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 4: Uram ecp course

4 Skills for ECP

Watching Video MonitorAccessing ciliary procesesses given approach and lens statusInflating ciliary sulcusControlling long duration, invisible wavelength laser

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 5: Uram ecp course

Anesthesia

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 6: Uram ecp course

Incision

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 7: Uram ecp course

LENS BEHIND IRIS: VISCOELASTIC

SINGLE CHAMBER EYE: INFUSION

AVOID HYPOTONY

ECP Treatment Principle

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 8: Uram ecp course

Inflating the Ciliary Sulcus

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 9: Uram ecp course

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Limbal, Over Bag / PC-IOLCombined Procedures:

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 10: Uram ecp course

No PPL for Phakic Eyes

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 11: Uram ecp course

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Curved Probe, Limbal

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 12: Uram ecp course

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Desired Tissue Effect

Whiten ciliary processes

Shrink ciliary processes

Treat entire ciliary process

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 13: Uram ecp course

Inflating the Ciliary Sulcus

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 14: Uram ecp course

Complete Treatment

INADEQUATE TREATMENT RESULTS IN:

POOR IOP CONTROL ONLY TEMPORARY “GOOD” RESULT

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 15: Uram ecp course

Treatment Zone

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 16: Uram ecp course

ECP: Post-Op Meds

SAME AS PHACO ALONE

IOP SPIKE PROPHYLAXIS

PARACENTESIS

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 17: Uram ecp course

ECP COLLABORATIVE STUDY GROUP

COMPLICATIONS

IOP Spike 14.5%Hemorrhage 3.8%Serous Choroidal Effusion 0.36%IOL Dislocation 0.36%CME 1.03%RD 0.27%Massive Choroidal Hemorrhage 0.09%Hypotony or Phthisis 0.12%NLP Vision 0.12%Cataract 24.5%Acute Graft Rejection 5.3%Chronic Graft Rejection 0Chronic Inflammation 0Flat AC 0Endophthalmitis 0Diplopia 0Wound Leak 0Bleb Complications 0

5824 PATIENTS

Page 18: Uram ecp course

707 Patients 626 Randomized to Phaco-ECP Group 81 Randomized to Phaco Alone 5 Surgeons Parameters such as VA, IOP, Meds, &

complications were followed

Mean follow-up was 3.2 years (0.5 to 5.8 years)

Phaco-ECP vs Phaco AloneStanley J. Berke, M.D., FACS, et. al..

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 19: Uram ecp course

Phaco-ECP vs Phaco Alone

Pre-opIOP

mmHg

Post-opIOP

mmHg

P Pre-opMeds

(#)

Post-opMeds

(#)

P

Phaco-ECP

19.08±

4.14

15.73±

3.00

4.48X

10 -72

1.53±

0.89

0.65±

0.95

1.23X

10 -85

Phaco Alone

18.16±

3.38

18.93±

4.12.01

1.20±

0.83

1.20±

0.870.50

ENDOSCOPIC CYCLOPHOTOCOAGULATION Martin Uram, M.D., M.P.H.

Page 20: Uram ecp course

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Phaco-ECP vs Phaco Alone: Medications at End of Follow-Up

no change increase decrease

Phaco-ECP Phaco Alone

27%

5%68%

12%

77%

11%

Page 21: Uram ecp course

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Phaco-ECP vs Phaco Alone: Post-Op IOP Change

no change increase decrease

Phaco-ECP Phaco Alone

9%

12%

79% 60%

38%

2%IOP

Page 22: Uram ecp course

Phaco-ECP vs Phaco Alone:Mean IOP Over Time

14

15

16

17

18

19

20Phaco-ECPPhaco Alone

Phaco-ECP 19.08 16.03 16.14 16.09 16.03

Phaco Alone 18.16 17.62 16.28 16.87 18.93

Pre-Op 6 Months 1 Year 2 Years 3 Years

mmHg 1.53 Meds

1.20 Meds

0.65 Meds

1.20 Meds

Page 23: Uram ecp course

Complications

No serious complications

were reported in either group

1 patient in each group

developed CME

Phaco-ECP vs Phaco Alone

Page 24: Uram ecp course

Phaco-ECP vs Phaco AloneGlaucoma Medication Cost Analysis

Pre-Op Post-Op Savings/Loss

Phaco-ECP monthly patient cost $220.08 $94.78 $125.30

Phaco-ECP annual patient cost $2,640.92 $1,137.35 $1,503.57

Phaco Alone monthly patient cost $144.45 $160.28 ($15.83)

Phaco Alone annual patient cost $1,733.40 $1,923.36 ($189.96)

Estimated US annual savings* $846,765,000

* 2.5 million cataract procedures annually. 20% of cataract surgery patients concurrently treated with glaucoma medications.

Page 25: Uram ecp course

Phaco-ECP: Conclusion

Hard to get in trouble It usually works It’s fun!