updated: april 2018 curriculum vitaevision.ucsf.edu/hortonlab//cv/horton_cv.pdf1 updated: april 2018...

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Updated: April 2018

CURRICULUM VITAE

Jonathan C. Horton MD PhD

Professor, Step VIII

Departments of Ophthalmology, Neurology, and Physiology

School of Medicine

University of California, San Francisco

PERSONAL DATA:

Date of Birth: 16 November 1954 Address and Telephone:

Department of Ophthalmology, K301

University of California, San Francisco

Place of Birth: Edmonton, Canada 10 Koret Way

San Francisco, California

94143-0730

Citizenship: United States

Languages: English - native 415-476-7176 (Office)

Spanish - fluent 415-476-8309 (Fax)

French - fluent 650-288-8736 (Cell)

e-mail: [email protected]

EDUCATION:

1972-1976 Leland Stanford Jr. University A.B. 1976 History

Thesis: Thomas Bradwardine and the Origins of

Modern Mechanics. Advisor: A.E. Bernstein, PhD

1976-1984 School of Medicine, Harvard University M.D. 1984 Medicine

1978-1983 School of Arts and Sciences, Harvard University Ph.D. 1984 Neurobiology

Thesis: Cytochrome Oxidase Patches: A New

Cytoarchitectonic Feature of Primate Visual Cortex.

Advisors: D.H. Hubel MD and T.N. Wiesel MD

1984-1985 Massachusetts General Hospital, Boston, MA Intern Medicine

1985-1986 Massachusetts General Hospital, Boston, MA Resident Neurology

1986-1989 Georgetown Univ Hospital, Washington, DC Resident Ophthalmology

1989-1990 University of California, San Francisco Fellowship Neuro-Ophthalmology

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Preceptors: W.F. Hoyt MD and C.S. Hoyt MD Pediatric Ophthalmology

LICENSES AND CERTIFICATIONS:

1985 Diplomate of the National Board of Medical Examiners, Number 225920

1989 Medical License, State of California, Number G 65872

1990 Diplomate of the American Board of Ophthalmology

1994 Fellow, North American Neuro-Ophthalmology Society

ACADEMIC POSITIONS:

1979-1983 Teaching Fellow, Department of Neurobiology, Harvard Medical School

1989-1990 Clinical Instructor, Department of Ophthalmology, UCSF

1990-1991 Assistant Clinical Professor, Department of Ophthalmology, UCSF

1991-1996 Assistant Professor in Residence, Department of Ophthalmology, UCSF

Director of Neuro-Ophthalmology, Fort Miley Veterans Hospital, San Francisco

1991-1996 Assistant Professor in Residence (WOS), Department of Neurology, UCSF

1996-1998 Associate Professor in Residence, Department of Ophthalmology, UCSF

1996-1998 Associate Professor in Residence (WOS), Department of Neurology, UCSF

1996-1998 Associate Professor in Residence (WOS), Department of Physiology, UCSF

1997-present Faculty Member, Program in Neuroscience, UCSF

1999-2002 Associate Professor, Department of Ophthalmology, UCSF

1999-2002 Associate Professor (WOS), Department of Neurology, UCSF

1999-2002 Associate Professor (WOS), Department of Physiology, UCSF

2001-2011 Vice-Chair for Clinical Science, Department of Ophthalmology, UCSF

2002-present Professor, Department of Ophthalmology, UCSF

2002-present Professor (WOS), Departments of Neurology and Physiology, UCSF

HONORS AND AWARDS:

1976 U.S. Public Health Service Fellowship, Division of Ophthalmology, Stanford University

1976 A.B. awarded with Honors, Stanford University

1976 Phi Beta Kappa, Stanford University

1976 James Birdsall Weter Prize, Stanford University (For Best Thesis in Department of History)

1977 Epilepsy Foundation of America, Medical Student Fellowship

1977 Boylston Medical Society, Harvard Medical School

1978 Medical Scientist Training (MD-PhD) Program Award, Harvard Medical School

1988 North American Neuro-Ophthalmology Society Resident/Fellow Award

1988 ARVO Travel Fellowship

1989 Heed Ophthalmic Foundation Fellowship

1989 Richard G. Scobee Memorial Fellowship

1990 North American Neuro-Ophthalmology Society Resident/Fellow Award

1993 Selected for Listing in Neuro-Ophthalmology Section of The Best Doctors in America, Woodward &

White Publishers, 3d Edition, 1994

1994 Nominated for a 1994 Kaiser Award for Excellence in Teaching, UCSF

1995 Nominated for an “Excellence in Small Group Instruction” award by the Class of 1995 for teaching in

Specialties 110 (Ophthalmology).

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1997 Nominated for an "Excellence in Small Group Instruction: Basic Sciences" Award by the Class of

2000, UCSF, for section teaching in Physiology 100.

1997 Membership, American Ophthalmological Society

1998 Nominated for the “Outstanding Lecture” Award by the Class of 2001

1998 Selected for Listing in Neuro-Ophthalmology Section of The Best Doctors in America, Woodward &

White Publishers, 4th Edition, 1999

1998 Appointed to the William F. Hoyt Endowed Chair in Ophthalmology

1999 Nominated for the “Outstanding Lecture” Award by the Class of 2002, UCSF

1999 Awarded the Troutman-Véronneau Prize by the Pan-American Association of Ophthalmology.

2000 Received the “Outstanding Lecture” Award from the Class of 2003, UCSF

2001 Awarded the Kimura Prize for Excellence in Teaching by the Ophthalmology Residents, UCSF

2001 Nominated for the “Outstanding Lecture” Award by the Class of 2004, UCSF

2002 Listed in Marquis Who’s Who

2002 Selected for Listing in Neuro-Ophthalmology Section of Best Doctors in America.

2002 Nominated for a Kaiser Award for Excellence in Teaching, 2002, UCSF.

2003 Nominated for “A Major Contribution to Teaching”, “Outstanding BMB Educator” and “Outstanding

Lecture Series” by the Class of 2005.

2003 Selected for inclusion in Best Doctors in America, 2003-2004 edition.

2004 Nominated for an “Outstanding Lecture Series” by the Class of 2006.

2005 Nominated for the 2005 Academic Senate Distinction in Teaching Award, Category 2

2005 Alcon Research Institute Award


2007 Selected by the Consumers’ Research Council of America for inclusion in the 2007 edition of the

Guide to America’s Top Ophthalmologists.


2008 Awarded the Bressler Prize by the Jewish Guild for the Blind, New York, N.Y.



2011 Osler Distinguished Teaching Award from the UCSF Class of 2011. (Funded by the UCSF Class of

1957 in honor of Sir William Osler).


2013 “Highly Commended Award” (1 of 3 awards, consisting of a ₤4,000 research prize) from the National

Centre for the Replacement, Refinement and Reduction of Animals in Research, Great Britain, for

our publication: Adams, D.L., Economides, J.R., Jocson, C.M., Parker, J, and Horton, J.C., A

watertight acrylic-free titanium recording chamber for electrophysiology in behaving monkeys. J.

Neurophysiology, 106:1581-90, 2011.


NAMED LECTURESHIPS:

1997 David Bodian Lecture, Johns Hopkins University

1999 The Harvard Lecture, Mass Eye and Ear Infirmary

2005 Karen Walker Lecture, UC Berkeley School of Optometry

2006 Canadian Journal of Ophthalmology Lecture, Toronto, Canada

2006 Carol F. Zimmerman Memorial Lecture, Southwestern Medical Center, Dallas, Tx

2007 Arthur W. Stickle Lecture, Washington University, St. Louis

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2008 Michael J. Hogan Lecture, Cordes Eye Society, San Francisco

2008 39th

Pinckney J. Harmon Memorial Lecture, Cajal Club

2011 William T. Shults Lecture, Devers Eye Institute, Portland, Oregon

2013 John Pratt-Johnson Lecture, University of British Columba, Vancouver, B.C., Canada

2018 Jacobson Lecture, North American Neuro-Ophthalmology Society Annual Meeting, 2018

2018 Fralick Lecture, University of Michigan.

GRANT SUPPORT:

1989 National Children's Eye Care Foundation Research Grant, "Effect of Monocular Visual Loss

Upon Metabolic Activity in Primate Visual Cortex", $5,000

1990 National Eye Institute Research Grant Award R03 EY08755-01, "Altered Metabolism of Primate

Visual Cortex in Amblyopia", $25,000

1990 Northern California Society to Prevent Blindness Research Award, "Metabolic Alterations in

Primate Visual Cortex Induced by Amblyopia", $8,298

1992 University of California Academic Senate Individual Investigator Grant, 1 Nov 1992 - 30 June 1993,

$21,506

1992 National Eye Institute Research Grant Award U10 EY09575-01, "Ischemic Optic Neuropathy

Decompression Trial". 15 June 1992 - 30 Nov 2000, $224,614 direct costs.

1993 National Eye Institute Research Grant Award R01 EY10217, "Structural Basis of Amblyopia in

Monkeys and Humans". 1 July 1993 - 30 June 1998, $689,202 direct costs.

1995 That Man May See Research Grant Award, "Quantitative Analysis of Ocular Dominance Columns in

Amblyopia", $35,979

1998 National Eye Institute Research Grant Award R01 EY10217-06-10, "Structural Basis of Amblyopia

and Strabismus". 1 July 1998 - 30 June 2003, $1,223,176 direct costs

1998 That Man May See Research Grant Award, “Cortical Mechanism of Visual Suppression in

Strabismus”, $31,000.

1999 Recipient, Lew R. Wasserman Merit Award, from Research to Prevent Blindness, N. Y., $55,000

2002 Larry L. Hillblom Foundation Clinical Research Grant, “Neural Mechanisms of Strabismus”, 1

December 2002 – 30 November 2005, $484,815 direct costs

2003 National Eye Institute Research Grant Award R01 EY10217, “Structural Basis of Amblyopia and

Strabismus”. 1 July 2003 – 30 June 2008, $1,800,460 direct costs.

2008 National Eye Institute Research Grant Award 2R56EY010217-16, “Structural Basis of Amblyopia

and Strabismus”. 1 July 2008 – 31 March 2009, $225,000 direct costs.


Strabismus”. 1 April 2009 – 31 March 2013, $1,000,000 direct costs.

2010 National Eye Institute Research Grant Award 3R01EY010217-16A1S1 issued under the American

Recovery and Reinvestment Act, 1 Jan 2010 – 31 Dec 2010, $167,538 direct costs.

2011 Recipient, Disney Award for Amblyopia Research, Research to Prevent Blindness, N.Y., $100,000.


Strabismus”. 1 Dec 2013 – 11/30/2018, $1,915,481 direct costs.

2014 Recipient, Physician Scientist Award, Research to Prevent Blindness, N.Y., $100,000.

SPECIAL ACTIVITIES:

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1984 Extern, Behrhorst Foundation Hospital, Chimaltenango, Guatemala (2/84-6/84)

1988 Ophthalmology Service, Eye Care Haiti, Leogane, Haiti (7/88-9/88)

PROFESSIONAL ACTIVITY:

Current Memberships:

1977- American Association for the Advancement of Science

1979- Society for Neuroscience

1986- American Academy of Ophthalmology

1988- The Association for Research in Vision and Ophthalmology

1988- The International Brain Research Organization

1988- North American Neuro-Ophthalmology Society

1997- The American Ophthalmological Society

1999- Pan-American Association of Ophthalmology

2008- The Cajal Club

Faculty Member, Basic and Clinical Science Course (BCSC), Section V (Neuro-Ophthalmology), American

Academy of Ophthalmology. Appointed June 1993-1997. Revised the AAO Neuro-Ophthalmology Manual

in collaboration with five other members.

Chair, Abstract Review Committee, North American Neuro-Ophthalmology Society. July 1995-Oct 1998.

Co-organized Special Interest Group Meeting entitled, "Fundamental Research Problems in Neurovision" for

the Association for Research in Vision and Ophthalmology (ARVO), Ft. Lauderdale, Fl, 19 May 1995.

Program Co-Chairman for Course entitled, "An Update in Neuro-Ophthalmology in Honor of William F.

Hoyt", Sponsored by Department of Ophthalmology, UCSF. 12/7-8/95.

Co-organized Symposium on Amblyopia at the North American Neuro-Ophthalmology Society, 22nd

Annual

Meeting, Salt Lake City, Utah, 2/12/96.

Grant Reviewer, Program for Sensory Systems, National Science Foundation, Arlington, VA, 1996

Prepared a historical poster about the Department of Ophthalmology, UCSF, for presentation at the

Centennial Annual Meeting of the American Academy of Ophthalmology, 27-31 Oct 1996, Chicago, Il.

Served as Chair of a Session Entitled "Visual System: Development I" at the 26th

Annual Meeting of the

Society for Neuroscience, Washington, D.C., 17 Nov. 1996.

Member of the Strabismus, Amblyopia, and Visual Processing Panel of the National Advisory Eye Council's

Vision Research Program Planning Subcommittee, National Eye Institute, National Institutes of Health,

Bethesda, MD., appointed Dec 1996.

Ad Hoc Study Section Member, Vision B Study Section, National Eye Institute, National Institutes of Health,

Bethesda, MD, 7 August 1997.

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Editorial Consultant, Scientific, Technical, and Medical Division, John Wiley & Sons, Inc., 1998.


Bethesda, MD, 9-10 February 2000.

Ad Hoc Study Section Member, ZEY1 VSN Study Section, National Eye Institute, National Institutes of

Health, Bethesda, MD, 26 March 2001.


Bethesda, MD, 13-14 June 2000.


Bethesda, MD, 10-11 October 2001.

Appointed as Regular Member, Vision B Study Section, National Eye Institute, National Institutes of Health,

Bethesda, MD, October 2001 - 2004.

Organized and Moderated Basic Science/Clinical Science Symposium on “Amblyopia” at Meeting for the

Association for Research in Vision and Ophthalmology (ARVO), Ft. Lauderdale, FL. 5 May 2002.

Chair, Central Visual Processing Study Section, National Eye Institute, National Institutes of Health,

Bethesda, MD, October 2003 – 2005.

Organized the “Tatsuji Inouye Brain Symposium” at the 16th

International Neuro-Ophthalmology Society

(INOS) Meeting, Tokyo, Japan. 1 December 2006.

.

Ad Hoc Study Section Member, Vision and Cognition (ZRG1 1FCN-G), National Institutes of Health,

Bethesda, MD. Feb 2007.

Ad Hoc Study Section Chairperson, Special Emphasis Panel (ZRG1 1FCN-E (03), National Institutes of

Health, Bethesda, MD. March 2007.

Ad Hoc Reviewer, Special Emphasis Panel (ZRG1 F02B Fellowship Review Panel), National Institutes of

Health, Bethesda, MD. 25 June 2007.

Ad Hoc Reviewer, Special Emphasis Panel (ZRG1 1FCN-G (02), National Institutes of Health, Bethesda,

MD. 4 Oct. 2007.

Ad Hoc Reviewer, Special Emphasis Panel (ZRG1 1FCN-A 03M, National Institutes of Health, Bethesda,

MD. 30 January 2008.

Ad Hoc Reviewer, Central Visual Processing Study Section, National Eye Institute, National Institutes of

Health, Seattle, WA. 9 June 2009.

Ad Hoc Reviewer, Special Emphasis Panel (ZRG1 1FCN-G (95) S, National Institutes of Health, Seattle,

WA. 9 June 2009.

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Member, Advisory Committee, Berkeley Clinical Science Development Program, NIH K12 Grant Program.

2009-2014.

Panel Member, National Eye Institute Strategic Planning Session, Strabismus, Amblyopia, and Visual

Processing Section (SAVP), 5 May 2011.

Ad Hoc Reviewer, Mechanisms of Sensory, Perceptual, and Cognitive Processes Study Section, National

Institutes of Health, San Francisco, CA., 2-3 February 2012.

Ad Hoc Reviewer, NIH Scientific Review Group: Sensory and Motor Neuroscience, Cognition and

Perception Fellowship Study Section [ZRG1 F02B-D], Washington, DC, 14-15 March 2013.

Member, Executive Advisory Board, Berkeley School of Optometry NEI P30 Core Grant 2013-.

Ad Hoc Reviewer, NIH Special Emphasis Panel ZRG1 BDCN-L (60) R-PAR 13-029: Opportunities for

Collaborative Research at the NIH Clinical Center, Washington, DC, 25-26 July 2013.


Institutes of Health, Washington DC, 16-17 June 2014.

Outside member, research faculty search committee for Neuro-Ophthalmology Division, Wilmer Eye

Institute, Johns Hopkins Hospital Spring 2015.

Ad Hoc Reviewer, NIH Scientific Review Group: Sensory and Motor Neuroscience, Cognition and

Perception Fellowship Study Section [ZRG1 F02B], San Francisco, 3-4 March 2016.


Institutes of Health, Washington DC, 17-18 October 2016.

Appointed to Scientific Advisory Board, Max Planck Institute, Tübingen, Germany. July 2017.

Appointed to Ad Hoc Committee to evaluate Dr. Gabriel Kreiman for appointment as Professor of

Ophthalmology, Harvard Medical School. March 2018.

Service to Professional Publications:

1987- Journal of Neuroscience Ad Hoc Referee

1988- Visual Neuroscience Ad Hoc Referee

1990- Survey of Ophthalmology Ad Hoc Referee

1992- Neurology Ad Hoc Referee

1992- Archives of Neurology Ad Hoc Referee

1992- Neurosurgery Ad Hoc Referee

1992- Annals of Neurology Ad Hoc Referee

1993- Ophthalmology Ad Hoc Referee

1993- Science Ad Hoc Referee

1993- American Journal of Ophthalmology Ad Hoc Referee

1994- Investigative Ophthalmology & Visual Science Ad Hoc Referee

http://public.csr.nih.gov/StudySections/IntegratedReviewGroups/ETTNIRG/F02B/Pages/default.aspx




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1995- British Journal of Ophthalmology Ad Hoc Referee

1995- Journal of Neuro-Ophthalmology Ad Hoc Referee

1995- Nature Ad Hoc Referee

1996- Cerebral Cortex Ad Hoc Referee

1997- Journal of Comparative Neurology Ad Hoc Referee

1997- Experimental Eye Research Ad Hoc Referee

1999- Optometry and Vision Science Ad Hoc Referee

1999-2003 Visual Neuroscience Member, Editorial Board

1999- Nature Neuroscience Ad Hoc Referee

2001- Lancet Ad Hoc Referee

2003 Neuroscience Ad Hoc Referee

2005- New England Journal of Medicine Ad Hoc Referee

2008- Visual Neuroscience Member, Editorial Board

2009- Journal of Neuro-Ophthalmology Member, Editorial Board

2010- Ophthalmic Genetics Ad Hoc Referee

2011- Neuron Ad Hoc Referee

2013- Annual Review of Vision Science Member, Editorial Board

Scientific Presentations at Professional Meetings:

(International)

1978 Eighth International Congress of Neuropathology, Washington DC

(Presented Abstract on Protein Transport across Blood-Brain Barrier)

1980 Biological Society of Chile, XXIII Annual Meeting, Vina del Mar, Chile

(Delivered Invited Lecture on Physiology of Primate Visual Cortex)

1992 IX International Neuro-Ophthalmology Symposium, Williamsburg, VA, 7/2/92

(Presented Abstract on the Representation of the Blind Spot in Human Striate Cortex)

1992 30th

Japan Neuro-Ophthalmology Society Meeting, Kobe, Japan, 10/15/92

(Featured Guest Speaker: "The Anatomical Basis of Amblyopia in Primate Visual Cortex)

1992 Xth

International Perimetric Society Meeting, Kyoto, Japan, 10/21/92

(Presented Abstract entitled: "Attenuation of the Ipsilateral Eye's Dominance Columns Between 20o-

60o in Human Striate Cortex Correlates with the Steeper Nasal Slope of the Hill of Vision")

1992 3rd

Japanese Glaucoma Society Meeting, Kyoto, Japan, 10/24/92

(Presented Invited Lecture on: "The Representation of the Blind Spot in Human Striate Cortex")

1993 XVth

World Congress of Neurology, Vancouver, Canada, 9/06/93

(Presented Invited Lecture: "The Cortical Representation of Vision")

1997 35th

Symposium, International Society for Clinical Electrophysiology of Vision, Asilomar, CA,

7/24/97 (Featured Guest Speaker: "Mapping the Human Visual Cortex")

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1999 XXII Congress of the Pan-American Association of Ophthalmology, Orlando, Fl, 10/25/99.

(Presented Invited Lecture: “Mapping of Suppression Scotomas in Striate Cortex of Macaques with

Experimental Strabismus”)

1999 31st Annual Scientific Congress of the Royal Australian College of Ophthalmologists, Melbourne,

Victoria, 11/17/99. (Invited Keynote Speaker: “Relative Magnification of the Central Visual Field

Representation in Striate Cortex of Macaques and Humans”. Also presented submitted abstract,

entitled, “Representation of the Purkyně Retinal Tree in Primate Striate Cortex”).

2000 14th

Latin-American Congress of Strabismus, Sao Paulo, Brazil, 5/11/00. (Invited Speaker at

Symposium sponsored by the Smith-Kettlewell Eye Research Institute. Gave talks entitled,

“Development of the Visual Cortex” and “Cortical Basis of Visual Suppression”).

2001 17th

Swiss Winter Ophthalmic Meeting, Grindelwald, Switzerland, 1/25-28/01. (Member, Scientific

Organizing Committee and gave talks entitled, “Neuro-Visual Complications of Herpetic Disease”

and “Pitfalls in the Diagnosis and Management of Papilledema”.

2001 4th

Meeting of the German Neuroscience Society, Göttingen, Germany, 6/7-6/9. (Invited Speaker at

Symposium entitled “Mechanisms of Map Formation in the Cortex: New Twists or Old Stories?”

Gave talk entitled, “The Cortical Representation of Shadows Cast by Retinal Blood Vessels: Lessons

for Ocular Dominance Column Formation”.

2002 IXth International Symposium of Ophthalmology, Santa Casa, São Paulo, Brazil, 7/4-7/6. (Presented

3 invited lectures entitled, “New Treatments for Optic Neuritis”, “Evaluation and Management of

Papilledema”, and “Amblyopia and Strabismus: Diseases of the Visual Cortex”).

2004 XVth Meeting of the International Neuro-Ophthalmology Society, Geneva, Switzerland, 7/19.

(Presented invited talk entitled, “A Direct Projection from the Lateral Geniculate Nucleus to Area

MT: Implications for Blindsight”).

2005 18th

Meeting of the Saudi Ophthalmological Society, Riyadh, Saudi Arabia, 3/6-3/9. (Presented 4

invited lectures entitled, “Thyroid Eye Disease”, “Management of Optic Neuritis”, “Ocular

Dominance: the Cortical Switch”, and “Visual Suppression in Strabismus”.

2006 XVIth Meeting of the International Neuro-Ophthalmology Society (INOS), Tokyo, Japan. 12/1/06.

Gave an invited talk entitled, “Variability of Ocular Dominance Columns in Human Striate Cortex”.

2008 XVIIth Meeting of the International Neuro-Ophthalmology Society (INOS), Napa, CA. 6/11/08.

Presented talk entitled, “High Resolution Mapping of Receptive Fields by Direct Stimulation of

Single Cones in the Primate Retina”.

2010 Keynote Speaker, 26th

Annual Meeting of the Neuro-Ophthalmology Society of Australia,

Christchurch, New Zealand. Presented lectures entitled, “Intracranial hypotension”, “Information

transfer at the lateral geniculate nucleus” and “Visual suppression in strabismus”. 9/2-3/10.

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2012 Invited Lecture, “Visual Suppression in Strabismus”, at the 116th

Japanese Ophthalmological Society

Meeting in Tokyo, Japan. 4/6/12.

2015 Keynote Speaker, 3d Meeting of the European Society for Low Vision Research and Rehabilitation

(ESLRR), Oxford, England. Presented lecture entitled, “Extrastriate pathways to visual perception”

9/26/2015.

2015 Invited Lecture, “Mechanisms of visual field loss from stroke: New data and ideas. 113th

meeting of

the Deutsche Ophthalmologische Gesellschaft (German Ophthalmological Society), Berlin, Germany.

10/3/15.

(National)

1980 Society for Neuroscience, 6th Annual Meeting, Atlanta, Georgia

(Presented Abstract on Cytochrome Oxidase Activity in Monkey Striate Cortex)

1981 Society for Neuroscience, 7th Annual Meeting, Cincinnati, Ohio

(Presented Abstract on Effects of Aminophosphonobutyrate on Cat Visual System)

1988 Association for Research in Vision and Ophthalmology Annual Meeting, Sarasota, Florida

(Presented Abstract on Ocular Dominance Columns in Human Visual Cortex)

1988 North American Neuro-Ophthalmology Society, 14th Annual Meeting, Crested Butte, CO

(Presented Abstract on Anatomy of Human Striate Cortex)

1990 North American Neuro-Ophthalmology Society, 16th Annual Meeting, Steamboat Springs, CO

(Presented Abstract on Quadrantanopia from Extrastriate Lesions in Human Visual Cortex)

1990 Frank Walsh Society, 21st Annual Meeting, Indianapolis, Indiana

(Delivered Invited Lecture on Metabolic Activity in Human Visual Cortex)

1991 North American Neuro-Ophthalmology Society, 17th Annual Meeting, Park City, Utah

(Delivered Invited Lecture on Representation of Visual Field in Human Striate Cortex)

1991 American Academy of Ophthalmology, 95th Annual Meeting, Anaheim, CA

(Invited Speaker in Scientific Session on Headache; Delivered Talk on Physiology of Migraine)

1992 American Academy of Neurology, 44th Annual Meeting, San Diego, CA

(Invited Lecture on Visual Cortex for Neuro-Ophthalmology Course, 5/4/92)

1992 Center for Visual Science Symposium, University of Rochester, Rochester, NY, 6/18/92

(Delivered Invited Lecture: "Human and Monkey Visual Cortex: How Close an Analogy?")

1992 Society for Neuroscience, 22nd

Annual Meeting, Anaheim, CA, 10/30/92

(Presented Abstract Entitled: "Anisometropia Induces Amblyopia Without Shrinkage of Ocular

Dominance Columns in Human Striate Cortex")

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1993 North American Neuro-Ophthalmology Society, 19th Annual Meeting, Big Sky, Montana

(Presented Abstract Entitled: "Neurovisual Findings in the Syndrome of Spontaneous Intracranial

Hypotension for Spontaneous Dural Cerebrospinal Fluid Leak")

1993 Frank B. Walsh Society, 25th Annual Meeting on 3/13/93, Rockefeller University, New York.

(Presented abstract entitled "Papilledema with Cortical Visual Loss")

1993 Society for Neuroscience, 23rd

Annual Meeting, Washington, DC, 11/10/93

(Presented Abstract Entitled: "Ocular Dominance Columns within the Foveal Representation of

Macaque Striate Cortex are Less Susceptible to Shrinkage Induced by Early Monocular Deprivation)

1994 North American Neuro-Ophthalmology Society, 20th Annual Meeting, Durango, Colorado,

2/28/94 (Presented Lecture: "Extrastriate Visual Cortex -- What Are We Doing with all that Brain

Tissue?")

1994 North American Neuro-Ophthalmology Society, 20th Annual Meeting, Durango, Colorado,

3/2/94 (Presented Abstract Entitled: "Salvage of Vision after Hypotension-Induced Ischemic Optic

Neuropathy")

1994 Society for Neuroscience, 24th

Annual Meeting, Miami Beach, Fl, 11/14/94 (Presented Abstract

Entitled: "Effect of Early Monocular Enucleation upon Cytochrome Oxidase Activity in Human and

Monkey Visual Cortex").


Annual Meeting, San Diego, CA, 11/16/95 (Presented Abstract

Entitled: "Newborn Monkeys have Well-Segregated Ocular Dominance Columns Organized in an

Adult-Like Mosaic Prior to Visual Experience").

1996 North American Neuro-Ophthalmology Society, 22nd

Annual Meeting, Salt Lake City, Utah, 2/12/96.

(Co-organized Symposium on Amblyopia and Gave Lecture Entitled: "Ocular Dominance Columns

in Human Amblyopia").


Annual Meeting, Salt Lake City, Utah, 2/13/96

(Presented Abstract Entitled: "Wilbrand's Knee of the Optic Chiasm is an Artefact of Long-term

Monocular Enucleation").


Annual Meeting, Washington, DC, 11/17/96 (Presented Abstract

Entitled: "Anatomical Demonstration of Ocular Dominance Columns in Striate Cortex of the Squirrel

Monkey").


Annual Meeting, Washington, DC, 11/20/96 (Presented Abstract

Entitled: "Intrinsic Variation in Ocular Dominance Column Periodicity in Normal Macaque

Monkeys").


Annual Meeting, Keystone, CO, 2/11/97

(Presented Abstract Entitled: "Retinal Input to the Primate Edinger-Westphal Nucleus".


Annual Meeting, New Orleans, 10/29/97 (Presented Abstract Entitled:

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"Relative Magnification of the Central Visual Field Representation in Striate Cortex of Macaques and

Humans").

1998 North American Neuro-Ophthalmology Society, 24th

Annual Meeting, Orlando, Fl, 3/24/98

(Presented Abstract Entitled: "Relative Magnification of the Central Visual Field Representation in

Striate Cortex of Macaques and Humans").


Annual Meeting, Los Angeles, 11/8/98 (Presented Abstract Entitled:

“Experimental Strabismus Reduces Metabolic Activity in Ocular Dominance Columns Serving the

Deviated Eye”).


Annual Meeting, Miami, Fl, 10/27/99 (Presented Abstract Entitled:

“Comparison of ocular dominance columns in normal and strabismic squirrel monkeys”).

2000 American Opththalmological Society, 136th

Annual Meeting, Monterey, CA, 5/22/00 (Presented

Abstract Entitled, “The cortical representation of shadows cast by retinal blood vessels”).

2001 Society for Neuroscience, 31st Annual Meeting, Miami, Fl, 11/11/01 (Presented Abstract Entitled:

“Pale cytochrome oxidase V2 stripes receive the richest projection from macaque striate cortex”).

2002 Society for Neuroscience, 32st Annual Meeting, Orlando, Fl, 11/04/02 (Presented Abstract Entitled:

“A decussation error in the optic chiasm revealed by an anomalous pattern of ocular dominance

columns in macaque V1”).


Annual Meeting, Salt Lake City, Utah,

02/11/03. (Presented Abstract Entitled: "Representation of Angioscotomas in Monkey Striate

Cortex”).

2004 Society for Neuroscience, 34th Annual Meeting, San Diego, CA 11/08/04 (Presented Abstract

Entitled: “How specific is V1 input to V2 thin stripes?).

2008 Association for Research in Vision and Ophthalmology, Ft. Lauderdale, Fl. 4/40/08 (Presented

research at a special interest group (SIG) meeting entitled, “Primate Models of Strabismus”.


Annual Meeting, Lake Tahoe, Nevada,

02/24/09. (Presented Abstract Entitled: "Seeing with Less: Image Compression at the

Retinogeniculate Synapse”).


Annual Meeting, Vancouver, Canada.

02/07/11. (Presented Invited Symposium Talk Entitled: "Visual Suppression in Alternating

Exotropia”).


Annual Meeting, Vancouver, Canada.

02/08/11. (Presented Platform Talk: “Color versus Form: Orientation Tuning of Cytochrome Oxidase

Patches in Macaque Primary Visual Cortex Explored with 100-Microelectrode Arrays”.

2011 Association for Research in Vision and Ophthalmology, Ft. Lauderdale, Fl. 5/4/11. (Presented

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invited talk entitled “Projections from V1 to V2 in Amblyopia” at a minisymposium on amblyopia).


Annual Meeting, Snowbird, Utah. 02/11/13.

(Presented Platform Talk: “Metabolic Activity in Primary Visual Cortex Matches Pattern of Visual

Suppression in Strabismus”).

2014 American Academy of Ophthalmology, Chicago, Il. 10/19/14. (Presented invited talk at Symposium

on “Tumors of the Brain and Orbits” entitled “Fooled by the Chiasm: Do Compressive Lesions

Always Produce Hemianopia?”


Annual Meeting, Washington DC 11/019/14 (Presented slide talk

entitled: “Vascular Supply of the Cerebral Cortex is Specialized for Cell Layers but Not Columns”.


Annual Meeting, Waikoloa Village, Hawaii,

03/06/18. (Presented Platform Talk: “Function of the Superior Colliculus in Strabismus”.


Annual Meeting, Waikoloa Village, Hawaii,

03/07/18. (Presented Jacobson Lecture: “Vascular Supply of the Occipital Lobe Explains Why

Certain Patterns of Visual Field Loss from Embolic Stroke are Common and Others are Rare”.

(Regional)

1991 Frederick C. Cordes Eye Society, 43rd Annual Meeting, San Francisco, CA

(Presented Talk on Hemianopia Caused by Occipital Lobe Abscess After Routine Dental Care)

1991 N. California Society to Prevent Blindness, Board of Directors Meeting, San Francisco, CA

(Presented Lecture on the Blind Spot in the Visual Field)

1992 Oregon Academy of Ophthalmology Monthly Meeting, Portland, Oregon

(Presented Lecture on the Discovery of the Visual Cortex)

1992 Peninsula Eye Society Monthly Meeting, San Jose, CA 9 April

(Presented Lecture on the Organization of the Human Visual Cortex)

1992 Ophthalmological Society of the Redwood Empire, Quarterly Meeting, Santa Rosa, CA 14 Dec

(Presented Lecture on Anterior Ischemic Optic Neuropathy)

1993 Mid-Peninsula Eye Society Meeting, 22 January

(Presented Talk on Evaluation of Acutely Swollen Optic Disc)

1993 Frederick C. Cordes Eye Society, 45th Annual Meeting, San Francisco, CA

(Presented Talk on Anterior Ischemic Optic Neuropathy)

1993 Mt. Zion Hospital, Quarterly Eye Department Meeting, San Francisco, CA

5/28/93 (Presented Talk on Optic Neuritis)

14

1994 Frederick C. Cordes Eye Society, 46th Annual Meeting, San Francisco, CA 4/8/94

(Presented Talk on Anterior Ischemic Optic Neuropathy and Carotid Artery Disease)


(Presented Talk entitled "Results of the IONDT Trial") 4/6/95


(Presented Talk entitled "Fluctuating Visual Acuity from Ersatz Rosenbaum Cards") 4/11/96

1997 East Bay Ophthalmological Society, Walnut Creek, CA 4/8/97

(Presented Talk entitled "Lesions of the Optic Chiasm")

2001 Frederick C. Cordes Eye Society, 53d Annual Meeting, San Francisco, CA 4/5/01

(Presented Talk entitled: "The Cortical Representation of Shadows Cast by Retinal Blood Vessels)

2008 Frederick C. Cordes Eye Society, 60th Annual Meeting, San Francisco, CA 4/4/08

(Presented Hogan Lecture entitled: "Putting the Eyes to Work Together: Binocular Integration in the

Human Visual Cortex”

2010 San Francisco Bay Area History of Medicine Club, San Francisco, CA. 2/10/10. (Presented lecture

entitled, “Tatsuji Inouye and the Discovery of the Retinotopic Map in the Primary Visual Cortex”.

Other Invited Lectures and Presentations:

1983 Seminar, Department of Physiology, University of California, Davis

1989 Neurology Grand Rounds, University of Rochester, Rochester, NY

1989 Seminar, Department of Ophthalmology, Yale University, New Haven, CN

1989 Seminar, Department of Ophthalmology, Washington University, St. Louis, MO

1990 Lecture, Visual Neuroscience Program, University of Iowa, Iowa City, IO

1990 Ophthalmology Grand Rounds, Stanford University, Stanford, CA

1991 Ophthalmology Grand Rounds, Washington Hospital Center, Washington DC

1991 Visiting Professor, Department of Ophthalmology, Georgetown University, Washington, DC

1991 Lecturer, Stanford Basic Sciences Course, Neuro-Ophthalmology Section


1992 Lecture, Neurology Grand Rounds, Kawasaki Medical School, Okayama, Japan, 10/19/92

1992 Lecture, Oxyopia Lecture Series, School of Optometry, UC Berkeley

1992 Seminar, Department of Neurobiology, Stanford University School of Medicine


1993 Neurology Grand Rounds, Stanford University, Stanford, CA 9/29

1993 Seminar, Georgetown University, Washington DC, 11/10/93

1994 Lecturer, Stanford Basic Science Course, Neuro-Ophthalmology Section

1994 Lecture entitled, "Amblyopia & Strabismus" at the National Eye Institute Course on Fundamental

Issues in Vision Research: Molecular and Cell Biological Approaches, Marine Biological Laboratory,

Woods Hole, Mass. 8/26/94.

1995 Visiting Professor, Department of Ophthalmology, University of Ottawa, Ottawa, Canada, 1/24-

25/95. Presented Lectures Entitled, "Cortical Architecture of Visual Processing", "Extrastriate

15

Cortical Visual Function", and "Transient Visual Loss".

1995 Lecture entitled, "The Human Visual Cortex: New Insights" for Ophthalmology Grand Rounds, Jules

Stein Eye Institute, UCLA. 3/8/95


1996 Lecturer, Alper Neuro-Ophthalmology Series, Washington National Eye Center, "Structural Basis of

Amblyopia" 1/6/96

1996 Lecture entitled, "Ocular Dominance Columns in Normal and Visually Deprived Humans",

Helmholtz Club, University of California, Irvine. 1/23/96.

1996 Lecture entitled, "Ocular Dominance Columns in Amblyopic Humans and Monkeys", Smith-

Kettlewell Eye Research Institute, San Francisco, CA. 6/6/96.


1996 Lecture entitled, "Amblyopia: A Disease of the Visual Cortex" at the National Eye Institute Course on

Fundamental Issues in Vision Research: Molecular and Cell Biological Approaches, Marine

Biological Laboratory, Woods Hole, Mass. 8/23/96.

1997 Invited Discussant at Workshop on Strabismus and Associated Visual and Visuomotor Phenomena

Sponsored by the National Eye Institute, Bethesda, MD, 4/14-15

1997 Visiting Professor, Departments of Neurology and Neurosurgery, University of Mississippi, 5/14-

16/97. Presented Lectures Entitled, "Organization of the Visual Cortex", "Pathologic Anatomy of

Wilbrand's Knee", "The Visual Cortex: What Are We Doing with so much Brain Back There?".

1997 Grand Rounds, Department of Ophthalmology, California Pacific Medical Center, San Francisco,

CA, 6/9/97. Presented Lecture "Lesions of the Human Optic Chiasm".


1997 Presented the David Bodian Seminar in Neuroscience, entitled "Ocular Dominance Columns: New

Functional Insights", at the Krieger Mind-Brain Institute, Johns Hopkins University, Baltimore, MD,

12/15/97.

1998 Lecture entitled "Diagnosis and Management of Papilledema" at the Universitäts-Augenklinik,

Zürich, Switzerland, 3/5.

1998 Featured Guest Speaker at Festschrift celebrating the 80th

birthday of Prof. Alfred Huber, Zürich ,

Switzerland, 3/6/98. Presented Lecture entitled: "Macular Sparing: the Gordian Knot Untied".

1998 Invited Speaker, Max-Planck-Institut für Biologische Kybernetik, Tübingen, Germany. Presented

Lecture entitled, "Monocular and Binocular Columns in Primate Striate Cortex", 3/9/98.

1998 Lecturer, Stanford Basic Science Course, Neuro-Ophthalmology Section.

1998 Lecture entitled, "Amblyopia and Strabismus" at the National Eye Institute Course on Fundamental



1998 Visiting Professor, Department of Ophthalmology and Neurology, University of Michigan, 10/22-24.

Presented lectures entitled “Topological Diagnosis of Chiasmal Disorders”, “Anatomy and

Physiology of the Primate Visual Pathways”, and “Neural Basis of Visual Perception”.

1999 Lecture entitled “Organization of the Human Visual Cortex” at the Universitäts Augenklinik, Vienna,

Austria, 1/11/99.

1999 Featured Guest Speaker, 1999 Meeting of the Viennese Ophthalmological Society, Vienna, Austria,

1/11/99. Presented lecture entitled, “Visual Suppression and Ocular Dominance Columns”.

1999 Invited Guest Speaker, Division of Neuroscience, Baylor University, Houston, Tx, 1/29/99.

Presented lecture entitled “Strabismus, Ocular Dominance Columns, and Visual Suppression”

1999 Invited Discussant, Smith-Kettlewell Eye Research Institute Pediatric Ophthalmology Journal Club,

1/3/99.

1999 Invited Speaker to a Conference “Critical Thinking about Critical Periods” held 2/24-26/99 in

16

Landsdowne, VA, sponsored by the U.S. Department of Education and the National Center for Early

Development and Learning. Presented lecture entitled “Critical Periods in the Development of the

Visual System” 2/24/99.

1999 Presented the Fifth Harvard Lecture in Ophthalmology in conjunction with the Annual Residents’

Course “Neuro-ophthalmology: A Subspecialty Perspective”. Massachusetts Eye and Ear Infirmary,

Boston, MA 3/12/99.

1999 Guest of Honor at the 675th

Meeting of the New England Ophthalmological Society. Presented

lectures entitled, “Chiasmal Dysfunction” and “Cortical Visual Disturbances”. Boston, MA, 5/21/99

1999 Invited Speaker at Gordon Research Conference on Neural Plasticity held 7/18-7-23 in Newport, R.I.

Presented talk entitled, “Function and Formation of Ocular Dominance Columns: Clues from

Strabismic Monkeys”.

1999 Lecturer, Stanford Basic Science Course, Neuro-Ophthalmology Section, 7/26

1999 Invited guest at the Neuro-Ophthalmology Society of Australia 15th

Annual Scientific Meeting,

Melbourne, Victoria, 11/19-20/99. Gave lectures entitled “Neural Basis of Visual Perception” and

“The Role of Ocular Dominance Columns in Visual Suppression” and submitted abstract entitled,

“Facial Pain and Vertical Diplopia in a Retired Boat Dealer”.

1999 Grand Rounds Speaker, Department of Medicine, Kaiser Permanente, Oakland, CA, 12/2/ Presented

lecture entitled, “Management of Temporal Arteritis”.

2000 Presented talk entitled “Representation of the Purkinje Retinal Tree in Primate Striate Cortex” at

Festschrift celebrating the 80th

birthday of Dr. Arthur Jampolsky, San Francisco, CA 4/10.

2000 Lecturer, Stanford Basic Science Course, Neuro-Ophthalmology Section, 7/18




2000 Invited Lecture entitled,”Compressive Lesions of the Anterior Visual Pathways”, at the 104th

Meeting

of the American Academy of Ophthalmology, in Symposium entitled, “Office Neuro-Ophthalmology

101: What the Comprehensive Ophthalmologists Needs to Know About Neuro-Ophthalmology”.

Dallas, TX 10/25.

2000 Invited Speaker, Washington, DC Neurology Society, Presented lecture entitled, “Pitfalls in the

Diagnosis and Management of Papilledema”. 11/3/00.

2000 Invited Speaker, Washington Hospital Center Grand Rounds, Washington DC. Presented lecture,

“Imaging Retinal Blood Vessels in the Brain”. 11/4/00

2000 Invited Speaker, Institute of Ophthalmology, University College London. Presented lecture, “Ocular

Dominance Columns in Strabismic Monkeys”. 11/20/00.

2000 Invited Speaker, Royal College of Medicine, London, England. Presented Lecture, “Cortical Basis of

Strabismic Suppression” at Symposium entitled, “Amblyopia: What do We Know and How Might it

Help”? 11/21/00.

2001 Invited Speaker, Universitätspital, Zurich, Switzerland. Presented Lecture, “Representation of

Retinal Blood Vessels in the Visual Cortex”. 1/29/01

2001 Featured Guest Speaker, Neurosurgery Resident’s Day, Department of Neurosurgery, SUNY Upstate

Medical University, Syracuse, NY. Presented Lecture, “Mapping the Grain of the Visual Cortex:

How Precisely Does the Brain Represent the World?” 4/7/01

2001 Invited Speaker, Max-Planck-Institut für Neurobiologie, Martinsried-Munich, Germany. Gave

seminar entitled, “A Precise Map of Primate Visual Cortex Generated from the Cortical

Representations of Angioscotomas”. 6/5/01.

2001 Invited Speaker, Max-Planck-Institut für Hirnforschung, Frankfurt am Main, Germany. Gave

seminar entitled, “A Precise Map of Primate Visual Cortex Generated from the Cortical

17

Representations of Angioscotomas”. 6/6/01.

2001 Lecturer, Stanford Basic Science Course, Neuro-Ophthalmology Section, 7/17/01

2001 Invited Speaker to Conference at The Banbury Center, Cold Spring Harbor Laboratory, N.Y. Gave

talk entitled “Cortical Maps”. 10/14/01.




2003 Featured Guest Speaker, University of Houston, College of Optometry 50th

Year Anniversary

Symposium, Houston, Tx. Presented Lecture, “Ocular Dominance Columns: A Contrivance of

Nature?” 3/2/03.

2003 Lecture entitled, “Development of the Visual Cortex” at the Cold Spring Harbor summer course

“Structure, Function, and Development of the Visual System”, Cold Spring Harbor, N.Y. 6/15/03

2003 Lecture entitled, “A New Foundation for the Visual Cortical Hierarchy” at the McDonnell Summer

Institute in Cognitive Neuroscience, Lake Tahoe, CA 6/26/03.

2003 Invited Speaker, Perspectives on Neuroscience Series, UC Davis. Gave lecture entitled, “The

Function of Ocular Dominance Columns”. 10/5/03.

2003 Invited Speaker, Stanford Brain Research Institute Seminar Series, Stanford University. Gave lecture

entitled, “Functional Architecture of Primate Visual Cortex”. 10/16/03.

2004 Invited Speaker, Neuro-Ophthalmologisches Symposium: The Expert’s Opinion. Zurich,

Switzerland. Gave lecture entitled, “Thyroid Eye Disease: Evaluation and Management”. 7/16/04.




2004 Invited Speaker, Neuroscience Program Seminar Series, University of California, San Diego. Gave

lecture entitled, “The Function of Cortical Columns”. 11/10/04.

2004 Invited Speaker, Scheie Eye Institute, Philadelphia, PA. Gave lectures entitled, “The Function of

Ocular Dominance Columns” and “Mapping the Visual Cortex: Pathways to Perception”. 12/3/04.

2005 Gave the “Karen Walker Lecture” at the UC Berkeley School of Optometry entitled, “Optic

Neuropathy in Clinical Practice: How Not to Get Burned” 1/9/05.

2005 Invited Speaker, University of Illinois College of Medicine, Peoria, Illinois. Gave Grand Rounds

entitled, “The Primate Visual System: Organization and Perception”. 5/6/05.

2005 Invited Speaker, The Montreal Neurological Institute, Montreal, Canada. Gave lecture entitled,

“Striate Cortex with and without Ocular Dominance Columns”. 9/16/05.

2005 Invited Speaker, Universitätsklinikum Tübingen, Germany. Gave lecture entitled “Cortical

Mechanisms of Strabismus” at Vision Symposium honoring Dr. Eberhart Zrenner. 11/5/05.

2006 Invited Speaker, Max-Planck-Institute for Biological Cybernetics, Tübingen, Germany. Gave

lecture entitled “Ocular dominance without ocular dominance columns” at a symposium on

“The Legacy of Ramon y Cajal”. 6/19/06.

2006 Invited Speaker, Canadian Ophthalmological Society Annual Meeting, Toronto, Canada.

Gave the Canadian Journal of Ophthalmology Lecture, entitled, “Ocular integration in the

human visual cortex”. 6/22/06.

2006 Lecture entitled, "Amblyopia and Strabismus" at the National Eye Institute Course on



2006 Invited Speaker, RIKEN Brain Science Institute, Saitama, Japan. Gave lecture entitled,

“Ocular Dominance Columns: the Conundrum of the Squirrel Monkey”. 11/28/06.

18

2006 Gave the 4th

Carol F. Zimmerman MD Memorial Lecture at Southwestern Medical Center, Dallas,

TX. Title: “Integration of Ocular Signals in the Visual Cortex”. 12/9/06.

2007 Presented lecture entitled, “Working Together: Ocular Integration in the Human Brain” at the Alcon

Research Institute 26th

Anniversary Awards Symposium, Fort Worth, Texas 2/17/07.

2007 Presented invited lecture entitled, “Probing Vision: from Monkeys to Patients” at the First Annual

Berkeley Conference on Translational Research – from Discovery to Application. School of

Optometry, Berkeley, CA 4/21/07.

2007 Presented seminar entitled “On the function of ocular dominance columns” sponsored by the

McDonnell Centers for Higher Brain Function, Washington University Program in Neuroscience, St.

Louis, MO. 5/15/07.

2007 Gave the Arthur W. Stickle Annual Lecture in Pediatric Ophthalmology in the Department of

Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO.

Title: “Binocular visual integration in the human brain”. 5/16/07.

2007 Gave an invited lecture entitled “Complete Pattern of Ocular Dominance Columns in Human Striate

Cortex” at the Optical Society of American Fall Vision Meeting, Berkeley, CA. 9/17/07.

2007 Grand Rounds speaker for Department of Ophthalmology, University of Medicine and Dentistry of

New Jersey. Gave lecture titled, “Binocular Function in the Human Brain”. Newark, NJ, 10/15/07.

2008 Presented lectured entitled “Bedside Evaluation of Diplopia” to Department of Neurology,

Washington Hospital Center, Washington, DC, 2/29/08.

2008 Presented lecture entitled “Neural Basis of Strabismus” for Mel Alper Neuro-Ophthalmology Rounds,

Washington Hospital Center. Washington DC, 3/1/08.

2008 Visiting Professor for the Medical Scientist Training Program (MSTP) Annual Meeting at the

Medical College of Wisconsin, Milwaukee, WI. Gave lecture entitled “Function of Ocular

Dominance Columns. 4/1/08.

2008 Lecture entitled, "Amblyopia and Strabismus" at the National Eye Institute Course on



2008 Presented the Pinckney J. Harmon Memorial Lecture, Cajal Club, UC Davis, Davis, CA. 9/25

2008 Grand Rounds speaker for Department of Neurology, Stanford University, Stanford CA. Gave

lecture entitled, “Binocular integration in the human brain”. 10/3.

2009 Presented lecture entitled, “Binocular visual function in strabismus”, Loris and David Rich

Lecture Series in Visual Science, University of Alabama, Birmingham. 3/25.

2009 Invited Speaker, ARVO Minisymposium on Strabismus and Amblyopia, Ft. Lauderdale, Fl,

5/13.

2009 Presented lecture, “Probing cone inputs to receptive fields in the lateral geniculate nucleus”

for the Neuroscience Seminar Program, Medical University of South Carolina, Charleston,

S.C., 6/4.

2009 Lecture entitled, “Striate Cortex” at the Cold Spring Harbor summer course “Structure, Function,

and Development of the Visual System”, Cold Spring Harbor, N.Y. 7/5/09.

2009 Presented Schnurmacher Institute for Vision Research Colloquium entitled, “Ocular Dominance

Columns and Strabismus”, SUNY College of Optometry, New York, N.Y. 7/7/09.

2009 Keynote lecture entitled, “Mapping of visual field suppression in strabismus”. Bielschowsky-

Gesellschaft für Schielforschung und Neuroophthalmologie. Tübingen, Germany, 11/21/09.

2009 Presented lecture, “Driving cells by single cone stimulation”. Department of Ophthalmology,

University of Zurich, Switzerland. 11/24/09.

2010 Presented lecture, “Binocular Function in Strabismus” for the Neuroscience Seminar Series, National

Institutes of Health, Bethesda, MD. 4/26.

19

2010 Presented talk “Color versus form: orientation tuning of cells in cytochrome oxidase patches of

macaque striate cortex. Oxyopia seminar series, UC Berkeley, 12/10/10.

2011 Presented talk, “Orientation tuning of cells in cytochrome oxidase patches”, Center for Visual

Science seminar series, UC Davis, 3/31/11.

2011 Keynote speaker at “Gained in Translation: A Symposium for the Vision Science Community”.

University of Washington, Seattle, WA. 6/1/11. Lecture title: Visual suppression in strabismus”.

2011 Presented lecture “Color versus form: orientation tuning of cells in cytochrome oxidase patches of

macaque striate cortex. University of Washington, Seattle, WA 6/1/11.

2011 Lecture entitled, “Functional Organization of Striate Cortex” at the Cold Spring Harbor Laboratory

summer course “Structure, Function, and Development of the Visual System”, Cold Spring Harbor,

N.Y. 7/11/11.

2011 Presented lectures entitled, “Visual function in the praying mantis”, “Fooled by the optic chiasm”,

and “What was that eye movement?”, Devers Eye Institute, Portland, OR. 9/15-16/11.

2011 Invited Guest at the British Isles Neuro-Ophthalmology Club (BINOC). Provided commentary on

case presentations and presented a talk entitled, “Horton’s Disease: a Tale of Two Branches”.

Belfast, Northern Ireland, 21-22 October.

2012 Featured speaker representing the subspeciality of Neuro-Ophthalmology for the 150 Augenklinik

Wissenschaftliches Symposium celebrating the 150th

anniversary of the founding of the Department

of Ophthalmology at the University of Zürich, Switzerland. 3/9/12.

2012 Featured Guest Speaker at “VisioNYC”, a thrice-yearly seminar series supported by the vision

training programs at Columbia, Cornell, NYU, and SUNY. Presented talk entitled: “Seeing double:

how the brain prevents it”. 5/21/12.

2012 Presented lecture entitled, “Double Vision: perception, suppression, and behavior” for the

Department of Neurosciences seminar series, Case Western Reserve University, 11/1/12.

2012 Presented talk entitled, “Suppression in Exotropia” at Clinical Problems in Strabismus Symposium,

Smith Kettlewell Eye Research Institute, 11/8/12.

2013 Presented lecture entitled, “Single vision, eyes askew: How the brain adapts to strabismus” for

Department of Anatomy and Neurobiology lecture series, University of California, Irvine, 5/30/13.

2013 Presented lecture entitled “Visual Suppression in Strabismus” at a Memorial Symposium Honoring

Peter Bishop at the University of Sydney, Australia, 28 June 2013.

2013 Presented a seminar entitled “Target Selection in Strabismus” at the Sydney Eye Hospital, Australia,

6/26/13.

2013 Presented lectures entitled “Does raised intracranial pressure occur in children without

papilledema?”, “Mapping suppression scotomas in strabismus”, “How the brain prevents double

vision”, “Sunken eyes, sagging brain syndrome”. Department of Ophthalmology and Visual Science,

University of British Columbia, Vancouver, BC, Canada. 9/6-7/2013.

2013 Presented lecture entitled “Visual Suppression in Strabismus” at Ophthalmology Grand Rounds,

Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 10/3/2013.

2013 Presented lecture entitled “Papilledema: Practice and Principles” at Neurology Grand Rounds,

Department of Neurology, Johns Hopkins University, Baltimore, MD 10/3/2013.

2013 Presented lecture entitled “Approach to Visual Loss” to Neurology Residents, Johns Hopkins

University, Baltimore, MD 10/03/2013.

2013 Presented lecture “Binocular Function in Strabismus” at a Festschrift for Ralph D. Freeman PhD at

the University of California, Berkeley 11/14.

2014 Presented lecture entitled “Visual Suppression in Strabismus” at Vision Seminar Series, University of

Pennsylvania, 2/3/14.

20

2014 Presented lectured entitled “Target Selection in Strabismus” for Scholars in Vision Science Seminar

Series Sponsored by the Center for the Neural Basis of Cognition, University of Pittsburgh and the

Carnegie Mellon University, 5/21.

2014 Visiting Professor, Children’s Hospital, Boston, MA. Presented lecture “Eye choice for target

acquisition in alternating exotropia”. 9/24.

2015 Presented lecture entitled “Vascular supply explains patterns of visual field loss from embolic cortical

stroke”, Department of Ophthalmology, Zurich, Switzerland, 9/29/15.

2015 Presented lecture entitled “Looking around: Eye choice for target acquisition in strabismus”, Sheldon

M. Golden Conference for Clinical Translational Research, UC Berkeley, 10/25.

2015 Keynote Speaker, Inaugural Symposium for the Center for Applied and Translational Sensory

Science, University of Minnesota, Minneapolis, MN. Presented lecture: “Perception and Adaption in

Strabismus”, 10/30.

2016 Presented talk entitled “Variability of Ocular Deviation in Strabismus” at Jampolsky Day

Symposium, CPMC, San Francisco, CA 3/21.

2017 Lecture entitled, “Binocular Function and Strabismus” at the Cold Spring Harbor Laboratory summer

course “Vision: A Platform for Linking Circuits, Behavior, and Perception”, Cold Spring Harbor,

N.Y. 6/17/17.

2017 Invited Lecture entitled, “Normal Topography and Binocularity of the Superior Colliculus in

Strabismus” at 29th

Annual Bay Area Vision Research Day, University of California, Berkeley, 9/15.

2017 Lecture, “Diagnosis of Eye Movements Disorders”, Department of Ophthalmology, Washington

Hospital Center, Washington DC, 10/11.

2017 Invited Lecture, “Visual Perception: Anatomy and Mechanisms”. Neurology Grand Rounds,

Washington Hospital Center, Washington, D.C. 10/14.

POSTGRADUATE AND CONTINUING EDUCATION:

1980 Attended 2 Month Course in Electrophysiological Methods for Cellular Neurobiology

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

1989-2017 I attended Grand Rounds, Department of Ophthalmology, UCSF, on a weekly basis and

met requirements for continued licensing and certification.

SERVICE TO THE UNIVERSITY OF CALIFORNIA:

1991-1995 Member, Primate User Subcommittee, Committee on Animal Research

1992-1995 Quality Care Assurance Committee, Ophthalmology Representative, Ft. Miley VA Hospital

1997 Chair, Fellowship Resources Committee, Department of Ophthalmology, UCSF

1999- Member, Animal Users Advisory Committee, UCSF

2000-2003 Chair, Library Committee, Department of Ophthalmology, UCSF

2000- Member, Curriculum Committee, Neuroscience Program, UCSF

2003-2006 Chair, Formal Seminar Series Program, Neuroscience Program, UCSF

2005 Chair, Search Committee for Director of Ocular Oncology Service, UCSF

(Resulting in change in series for Dr. Joan O’Brien)

2005 Chair, Search Committee for Basic Science Faculty Position, UCSF

(Resulting in hire of Dr. Douglas Gould). Served on mentorship committee.

21

2005 Breakout Session Leader for Junior Faculty Development Workshop, UCSF, 7/22

2006 Member, Search Committee for Oculoplastics/Neuro-Ophthalmology Faculty Position, UCSF

(Resulting in hire of Dr. Timothy McCulley) . Served on mentorship committee.

2006 Member, Search Committee for Chair, Department of Ophthalmology, UCSF

(Resulting in appointment of Dr. Stephen McLeod)

2006-2011 Chair, Grand Rounds Committee, Department of Ophthalmology, UCSF

2007-2011 Member, Ophthalmology Faculty Promotions Committee

2007 Chair, Search Committee for Pediatric Ophthalmology Faculty Position, UCSF

(Resulting in hire of Dr. Tina Rutar)

2007-2008 Member, Ad Hoc Committee to Review the Operation of the IACUC

2010-2011 Appointed by Dr. Sally Marshall, Vice Provost, to Stewardship Committee Reviewing the

Performance of Dr. Stephen Hauser, Chair of the Department of Neurology.

2013 Appointed by Dr. Sally Marshall, Vice Provost, to Stewardship Committee Reviewing the

Performance of Dr. James Wells, Chair of the Department of Pharmaceutical Chemistry,

School of Pharmacy, UCSF.

2017 Served on mentorship committee for Xin Duan PhD.

PUBLIC SERVICE:

1991 Scientific Advisor for Exhibit "Mosaic Vision", The Exploratorium, San Francisco, CA

1998-now Area Q Representative, Highlands Community Association, San Mateo, CA

1999-2000 Elected Vice-President, Highlands Community Association, San Mateo, CA

4/16/16 Presentation to S.F. High School students for UCSF Early Academic Outreach Program

TEACHING:

Formal Scheduled Class at UCSF:

Qtr Year Course Contribution Units Number of Students

Sum 1990 Specialties 110 Course Director 6 16

Ophthalmology

Win 1991 Specialties 110 Course Director 6 14

Ophthalmology


Ophthalmology


Ophthalmology


Ophthalmology

22


Ophthalmology

Spr 1996 Specialties 110 Course Director 6 12

Spr 1992 Anatomy 103 Section Co-instructor 10 15

Spr 1996 Physiology 100 Section Leader 6 12

Spr 1997 Physiology 100 Section Leader 6 15

Win 1998 Neuroscience 201B Lecturer 6 14

Spr 1998 Anatomy 103 Lecturer 10 150

Spr 1998 Physiology 101 Section Leader 11





Win 2000 Neuroscience 240 Course Co-Director 3 18




Win 2001 Anatomy 103 Lecturer 10 150



Spr 2002 IDS 104 Lecturer 150




23



Win 2005 Neuroscience 201B Course Co-Director 18


Win 2006 Neuroscience 201B Course Co-Director 14



Win 2007 Neuroscience 201B Course Co-Director 3 14


Win 2008 Neuroscience 201B Course Co-Director 3 18

Win 2008 Neuroscience 221 Discussion leader 6




Fall 2009 Neuroscience 221 Discussion leader 10

Fall 2009 Neuroscience 240 Course-Co-director 5



Win 2011 Neuroscience 201B Lecturer 15





Win 2014 Neuroscience 201C Lecturer 19

24



Spr 2016 IDS 104 Small group instructor 10

Win 2017 Neuroscience 201C Lecturer, Discussion leader 18

Win 2018 Neuroscience 201C Lecturer, Discussion leader 16

Formal Scheduled Class at School of Optometry, UCB:

S 1990 Course 136B Guest Lecturer 4 120

S 1992 Course 452 Guest Lecturer 4 120

W 1993 Course 135 Guest Lecturer 4 120

CME Courses:

1990 Presented Lecture for Course: "New Ideas on Common Retinal Disorders"

Sponsored by the Department of Ophthalmology, UCSF

1991 Presented Lecture for Course: "New Ideas and Controversies in Ophthalmology"

Sponsored by the Department of Ophthalmology, UCSF

1992 Presented Lecture Entitled: "Surgical Management of Papilledema" for the 25th Annual Course on

"Recent Advances in Neurology", Sponsored by the Department of Neurology, UCSF

1992 Presented Lecture for Course, "2nd Annual Berkeley Comes to You"

Sponsored by the School of Optometry, University of California

1992 Presented Lecture Entitled: "Visual Complications after Non-Ophthalmic Surgery" for Course on

"Ophthalmic Surgical Complications" Sponsored by the Department of Ophthalmology, UCSF

1993 Presented Lecture Entitled: "Ischemic Optic Neuropathy" for the 26th Annual Course on "Recent

Advances in Neurology", Sponsored by the Department of Neurology, UCSF

1993 Presented Lecture Entitled: "Evaluation of Acute Optic Disc Edema" for "Ocular Symposium VI"

Sponsored by University of California Optometry Alumni Association, 6/5/93

1994 Presented Lecture Entitled: "Organization of Human Extrastriate Visual Cortex" for the 27th

Annual Course on "Recent Advances in Neurology", Sponsored by the Department of Neurology,

UCSF, 2/17/94.

25

1994 Presented Lecture Entitled: "Glaucoma in Patients with Carotid-Cavernous Fistula: Mechanism and

Management" for Course on "New and Practical Approaches to Glaucoma Management", Sponsored

by the Department of Ophthalmology, UCSF. 12/9/94.

1994 Presented Lecture Entitled: "Glaucomatous Field Defects from Structural Anomalies of the Optic

Disc" for Course on "New and Practical Approaches to Glaucoma Management", Sponsored by the

Department of Ophthalmology, UCSF. 12/9/94.

1995 Presented Lectures Entitled: "Evaluation and Management of Transient Visual Loss", "Ocular

Infections in Neuro-Visual Disease, and "Pitfalls in Neuro-Visual Diagnosis" for Course, "Fifth

Annual Berkeley Comes to You", Sponsored by School of Optometry, University of California,

Berkeley, 3/4/95.

1995 Presented Lecture Entitled: "Wilbrand's Knee 1904-1995 R.I.P." for Course "An Update in Neuro-

Ophthalmology" Sponsored by the Department of Ophthalmology, UCSF, 12/7/95.

1996 Presented Lecture Entitled: "Optic Nerve Disorders" for 46th

Annual Education Program and Reunion

of the Optometry Alumni Association of the University of California, Berkeley, 10/19/96.

1997 Presented Lecture Entitled: "Status of Optic Nerve Sheath Fenestration: To Slit or Not to Slit?" for

Course on "Ophthalmic Plastic Surgery for the 21st Century", Sponsored by Department of

Ophthalmology, UCSF, 12/12/97.

1998 Presented a “Neuro-Ophthalmology Update”, consisting of 3 lectures entitled, “The Holmes Map

Revisited: Localization in the Human Visual Cortex”, “The Anatomy and Physiology of Amblyopia”,

and “Visual Field Cases: Let’s Play Where’s the Lesion”. Cleveland Clinic Foundation Eye Institute,

Cleveland Ohio, 12/5.

1998 Presented Lecture Entitled: “Cortical Basis of Strabismus and Amblyopia” for Course on “Pediatric

Ophthalmology: Seeing Straight into the Future”, Sponsored by Department of Ophthalmology,

UCSF, 12/15.

1999 Presented Lecture Entitled: “Temporal Arteritis” for the 32d Annual Course on "Recent Advances in

Neurology", Sponsored by the Department of Neurology, UCSF, 2/10/99.

1999 Presented Lecture Entitled: “Pseudoglaucomas” for the 49th

Annual Educational Program and

Reunion of the Optometry Alumni Association, UC School of Optometry, Berkeley, CA, 10/16.

2001 Presented Lecture Entitled: “Disasters and Near-Disasters in the Diagnosis and Management of

Papilledema” for the 34th

Annual Course on “Recent Advances in Neurology”, Sponsored by the

Department of Neurology, UCSF, 2/14/01.

2001 Presented Lectures Entitled: “Management of Optic Neuritis” and “Amaurosis Fugax & Retinal

Arteriole Emboli” for the 51st Annual Educational Program and Reunion of the Optometry Alumni

Association, UC School of Optometry, Berkeley, CA, 10/20/01.

2001 Presented Lecture Entitled: “New Treatments for Optic Neuritis” for Course on “Techniques &

26

Technologies for 2002”, Sponsored by Department of Ophthalmology, UCSF, 12/07.

2003 Presented 4 lectures entitled: “Putting the eyes to work together: human ocular dominance columns”,

“Visual suppression: the cortical switch”, “A metabolic imprint of retinal blood vessels in the visual

cortex”, and “Mapping the brain: the last great frontier” for Course “Pediatric Ophthalmology, Adult

Strabismus, Sponsored by Department of Ophthalmology and Visual Sciences, The University of

British Columbia, Vancouver, Canada, 9/6/03.

2003 Presented Lecture Entitled: “Radiation Therapy for Graves’ Orbitopathy” for Course on “The Lay of

the Land 2004”, Sponsored by Department of Ophthalmology, UCSF, 12/12/03.

2005 Presented Lecture Entitled, “Evaluation and Management of Thyroid Eye Disease” for the 38th

Annual Course on “Recent Advances in Neurology”, UCSF, 2/17/05.

2005 Presented Lecture Entitled, “A New Photoreceptor: the Retinal Ganglion Cell” for Course

“Ophthalmology 2006: New Directions in Ocular Therapies”, Sponsored by Department of

Ophthalmology, UCSF, 12/1/05.

2007 Presented Lecture Entitled, “What’s That Crazy Eye Movement” for the 40th

Annual Course on

“Recent Advances in Neurology”, UCSF, 2/16/07.

2007 Presented Lecture Entitled, “Doctor, My Eyes -- Tell Me What Is Wrong” for Course

“Ophthalmology 2007”, Sponsored by Department of Ophthalmology, UCSF, 12/14.

2008 Presented Lecture Entitled, “Neuro-Ophthalmology of Pituitary and Parasellar Disorders” for Course

“Pituitary Disorders: Advances in Diagnosis and Management”. Sponsored by Department of

Neurosurgery and the California Center for Pituitary Disorders, UCSF, 3/15.

2008 Presented Lecture Entitled, “When Can You Stop Treating Amblyopia” for Course “Ophthalmology

2008”, Sponsored by Department of Ophthalmology, UCSF, 12/12 (Audio-Digest Ophthalmology,

Vol. 47, Issue 5, 7 March 2009).

2009 Presented Lecture Entitled, “Missing the Chiasmal Tumor” for the 42d Annual Course on “Recent

Advances in Neurology”, UCSF, 2/11.

2009 Presented Lecture Entitled, “Fooled by the Chiasm”, Ophthalmology Update 2009, sponsored by

Department of Ophthalmology, UCSF. 12/12/2009.

2010 Presented Lectures Entitled, “Thyroid eye disease”, “Falling out of the sella turcica”, and “What’s

that weird eye movement” for NeuroVision course, Christchurch, New Zealand, 9/4-5/10.

2010 Presented Lecture Entitled, “Achieving Ocular Fusion in Graves’ Orbitopathy”, Ophthalmology

Update 2010, sponsored by Department of Ophthalmology, UCSF. 12/3/2010.

2011 Presented Lecture Entitled, “Under Pressure: Highs, Lows, and the Fading of Vision” for the 44th


27

2011 Presented Lecture Entitled, “Intracranial Pressure: Highs and Lows”, Ophthalmology Update 2011,

sponsored by Department of Ophthalmology, UCSF. 12/2/2011. (Audio-Digest® Ophthalmology,

“Selected Topics in Neuro-Ophthalmology”, Volume 50, Issue 17, September 7, 2012).

2012 Presented Lectures Entitled, “Approach to Visual Loss”, “Optic Neuropathies”, “Chiasmal

Syndromes”, “Thyroid Eye Disease”, “Cortical Disorders of Vision”, “Guide to Visual Field

Analysis”, “Video Quiz of Eye Movement Disorders” at Forum for Indian Neurology Education,

Agra, India, 23-24 August 2012.

2013 Presented Lecture Entitled, “Reasonable Doubt: Can High Intracranial Pressure Occur Without

Papilledema?” for the 46th


2013 Presented Lecture Entitled, “Can High Intracranial Pressure Occur without Papilledema”

Ophthalmology Update 2013, sponsored by Department of Ophthalmology, UCSF. 12/6.

2014 Presented Lectures Entitled, “Approach to Visual Loss”, “Optic Neuropathies”, “Chiasmal

Syndromes”, “Cortical Disorders of Vision”, “Guide to Visual Field Analysis”, “Video Quiz of Eye

Movement Disorders” at Forum for Indian Neurology Education, Pune, India, 23-24 August 2014.

2014 Invited participant, “Neuro-Ophthalmology Fall Festival”, Massachusetts Eye and Ear Infirmary,

Harvard Medical School, Boston, MA. Served as expert panelist and gave talk entitled, “Vascular

supply of the occipital lobe explains why certain patterns of visual field loss from embolic stroke are

common and others are essentially “prohibited”. 8-9 Nov 2014.

2014 Presented Lecture Entitled, “Monovision Trashes Binocular Vision”. Ophthalmology Update 2014,

sponsored by Department of Ophthalmology, UCSF. 12/12.

2015 Presented Lecture Entitled, “Approach to Unexplained Vision Loss”, 26th

Annual Berkeley

Practicum, School of Optometry, UC Berkeley, CA, 1/18.

2015 Presented Lecture Entitled, “The Battle for Binocular Vision”, for the 48th

Annual Course on “Recent

Advances in Neurology”, UCSF, 2/12/15.

2015 Presented Lecture Entitled, “Spontaneous Regeneration of Human Cones”. Ophthalmology Update

2015, sponsored by Department of Ophthalmology, UCSF. 12/4.

2016 Presented Lecture Entitled, “In Flagrante Delicto: Capturing the moment when fusion is lost in

strabismus. Ophthalmology Update 2016, sponsored by Department of Ophthalmology, UCSF. 12/2.

2017 Presented Lectures Entitled, “Visual Physiology and Anatomy: A Primer from Retina to Cortex”,

Approach to Visual Loss of Unknown Cause”, “Cortical Disorders of Vision”, “Visual Fields:

Analysis and Interpretation”, “Fundoscopy: Disc, Arteries, Veins, and Retina”, “Video Quiz of Eye

Movement Disorders” at Forum for Indian Neurology Education, Mumbai, India, 4-6 August 2017.

2017 Presented Lecture Entitled, “Ambulatory Monitoring for Detection of Strabismus”, Ophthalmology

Update 2017, sponsored by Department of Ophthalmology, UCSF. 12/1.

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Lectures and Presentations at UCSF:

11/1989 Grand Rounds Speaker, Department of Ophthalmology

1/1990 Research Seminar, Department of Ophthalmology

3/1990 Grand Rounds Speaker, Department of Neurosurgery

7/1990 Lecture, Introductory Course for New Ophthalmology Residents


9/1990 Lecture, "Basics of the Neuro-Visual Exam" for New Neurosurgery Residents

10/1990 Lecture, Microsurgical Course for First-Year Ophthalmology Residents


4/1991 Grand Rounds Speaker, Department of Neurology

4/1991 Lecture, Basic Science Course, Department of Ophthalmology


7/1991 Faculty Participant for Ophthalmology Residents' Monthly Journal Club




9/1991 Lecture, "Basics of the Neuro-Visual Exam for Neurosurgery Residents"


12/1991 Lecture, "Visual Pathways", Neurology/Neuroscience Lecture Series





8/1992 Lecture, "The Neuro-Visual Exam" for New Neurosurgery Residents





9/1993 Lecture, "Basics of the Neuro-Visual Exam for Neurosurgery Residents"


10/1993 Lecture, Retina Course for New Ophthalmology Residents

3/1994 Lecture, "Internuclear Ophthalmoplegia" to Neurology Residents

3/1994 Lecture, "Transient Visual Loss" to Neurology Residents



7/1994 Lecture, "The Neuro-Ophthalmological Examination" for Neurosurgery Residents

7/1994 Lecture, "Neuro-Ophthalmology Part 1" for New Ophthalmology Residents




4/1995 Grand Rounds, "Blindness after Hypotensive Spinal Anesthesia", Department of Anesthesia

5/1995 Lecture, "Errors in Neurovisual Diagnosis" to Neurology Residents




29

9/1995 Lecture, "Basics of the Neuro-visual Exam for Neurosurgery Residents



5/1996 Grand Rounds Speaker, Department of Ophthalmology, "How to manage optic neuritis and

AION: Results of the ONTT and IONDT studies".

5/1996 Faculty Host for Ophthalmology Residents' Journal Club




8/1996 Lecture, "Basics of the Neuro-visual Exam for Neurosurgery Residents

10/1996 Seminar, "Definition of the critical period for plasticity of ocular dominance columns in

macaque striate cortex", Department of Physiology (10/1/96).

12/1996 Lectures on Neuro-Ophthalmology for Fundamentals of Ophthalmology Course

2/1997 Lecture to Medical Scientist Training Program (MD-PhD) students (Course 170.09)

4/1997 Neuroscience Informal Seminar, "Timing of the Critical Period for Plasticity of Ocular

Dominance Columns in Macaque Striate Cortex", 4/29.

5/1997 Lecture, "Oculomotor Disorders", to Neurology Residents, 5/7




9/1997 Lecture, UCSF Program in Neuroscience Meeting, Asilomar, CA, 9/14

10/1997 Lecture, "Eye Movement Disorders in Neuro-Ophthalmology, Part 1" to Neurology

Residents, 10/8

10/1997 Lecture, "Eye Movement Disorders in Neuro-Ophthalmology, Part 2", to Neurology

Residents, 10/22

4/1998 Lecture, “Evaluation of Optic Disc Swelling” for Ophthalmology Residents, 4/9.

8/1998 Grand Rounds, Department of Neurology, “Optic Chiasm Disorders”, 8/28.

9/1998 Lecture, UCSF Program in Neuroscience Meeting, Asilomar, CA, 9/17

12/1998 Lectures on Neuro-Ophthalmology for Fundamentals of Ophthalmology Course

1/1999 Lecture, “The Neuro-Visual Exam, Part 1”, to Neurology Residents, 1/20

1/1999 Lecture, “The Neuro-Visual Exam, Part 2”, to Neurology Residents, 1/27

4/1999 Lecture, Program in Biological Science (PIBS), Thursday evening faculty lecture series

9/1999 Grand Rounds Speaker, Department of Ophthalmology, UCSF, “Temporal Arteritis”, 9/17

1/2000 Lecture, “Papilledema, Pseudopapilledema, and Papillitis” for Ophthalmology Residents, 1/27

3/2000 Lecture, “Evaluation and Management of Optic Disc Edema” for Neurology Residents, 3/23

7/2000 Lecture, "Neuro-Ophthalmology Part 1" for New Ophthalmology Residents, 7/28

7/2000 Lecture, "Neuro-Ophthalmology Part 2" for New Ophthalmology Residents, 7/31

12/2000 Lecture, “Eye Movement Abnormalities”, for Ophthalmology Basic Science Course, 12/14

2/2001 Grand Rounds Speaker, Department of Ophthalmology, UCSF, “Papilledema”, 2/1.

7/2001 Lecture, Introduction to Neuro-Ophthalmology” for New Ophthalmology Residents, 7/25

10/2001 Lecture, “Metabolic Images of the Visual Cortex”, for Neuroradiology Research Rounds, 10/9

12/2001 Lecture, “Disorders of Eye Movements”, for Ophthalmology Basic Science Course, 12/13.

5/2002 Lecture, “Diagnosis of Optic Disc Edema” for Neurology Residents, 5/23.

7/2002 Lecture, “Introduction to Neuro-Ophthalmology” for New Ophthalmology Residents, 7/16

8/2002 Lecture, “The Neuro-Ophthalmology Service at UCSF” for Ophthalmology Staff, 8/1

12/2002 Lecture, “Disorders of Eye Movements”, for Ophthalmology Basic Science Course, 12/12

5/2003 Small Group Discussion Leader for session on brainstem anatomy, Brain, Mind, Behavior

30

IDS104. 5/5/12

5/2003 Public Lecture, “A Window on the World: The Eyes, Brain, and Perception” for Mini-Med V,

Sponsored by Public Affairs, UCSF, 5/14

7/2003 Lecture, “Introduction to Neuro-Ophthalmology” for New Ophthalmology Residents

12/2003 Lecture, Basic Science Course for Ophthalmology Residents

2/2004 Frontiers in Neurology & Neuroscience, Department of Neurology, “"Eye movements: why

they break, how they work". Presented in conjunction with Dr. Stephen Lisberger. 2/4/04

5/2004 Public Lecture, “The Amazing Visual System”, for the Osher Institute of Lifelong Learning

Program on: “Brain and Mind: A Remarkable Universe.”


9/2004 Grand Rounds Speaker, Department of Neurosurgery, UCSF, “Exploring the Primate Visual

Cortex. 9/9.

12/2004 Lecture, “Clinical Management of Optic Neuropathy” for Fundamentals of Ophthalmology

Course, 12/14

3/2005 Housestaff Conference, Department of Neurology, “Evaluation of Diplopia”.


8/2005 Housestaff Conference, Department of Neurology, “The Bedside NeuroVisual Exam”, 8/24


7/2006 Lecture, “Neuro-Visual Emergencies” for Neurology Residents, 7/19

12/2006 Grand Rounds Speaker, Department of Neurology, UCSF. “Integration of Ocular Signals in

the Human Visual Cortex”.

4/2007 Fundamentals of Ophthalmology Course, UCSF Ophthalmology Residents, 4/4


7/2007 Lecture, “The Bedside Neuro-Ophthalmology Exam” for Neurology Residents, 7/11


6/2008 Techniques in Eye Muscle Surgery for UCSF Ophthalmology Residents, 6/05




9/2009 Lecture to medical students in Introduction to Ophthalmology Elective, 9/23


4/2010 Sensory Testing in Strabismus, UCSF Ophthalmology Residents, 4/22


11/2010 Lecture to medical students in Introduction to Ophthalmology Elective, 11/8


6/2011 Lecture “Exploration of the Visual Cortex” to UCSF Emeritus Faculty Association, 6/9



8/2012 Lecture, “Approach to Vision Loss” for New Ophthalmology Residents, 8/17

8/2012 Lecture, “Optic Neuropathies” for New Ophthalmology Residents, 8/17

9/2012 Grand Rounds Lecture, Department of Neurosurgery, UCSF, “Low Intracranial Pressure”,

9/27



3/2014 Lecture, “Cortical Disorders of Vision” to Ophthalmology Residents 3/13

4/2014 Small group session leader for BMB course teaching ophthalmology skills, 4/16

4/2014 Small group session leader for BMB course teaching ophthalmology skills, 4/18

31



2/2015 Grand Rounds Lecture, Medical Scientist Training Program, “Target Selection in Alternating

Strabismus”, UCSF, 2/14.

4/2015 Direct ophthalmoscopy training session for first year medical students 4/21.


2/2016 Lecture, “Cortical Disorders of Vision” to Ophthalmology Residents 2/4

7/2016 Lecture, “Neuro-Ophthalmology Emergencies” for New Ophthalmology Residents, 7/8


11/2016 Lecture, “Extraocular Muscles” for Ophthalmology Residents 11/3

11/2016 Lecture, “Optic Neuropathies” for Ophthalmology Residents 11/30

1/2017 Vision Breakfast Seminar, “Intermittent Exotropia”, 1/5

1/2017 Lecture, “Recognizing an Object” for Ophthalmology Residents 1/19

3/2017 Lecture, Cranial Nerves in Ophthalmology for Residents, 3/16

6/2017 Chalk Talk, Systems Neuroscience Faculty, 6/2

7/2017 Lecture, “Neuro-Ophthalmology Emergencies” for New Ophthalmology Residents, 7/25


7/2017 Grand Rounds Lecture, “Ocular Motility Disorders”, Department of Neurosurgery, 7/27.

9/2017 Lecture, “Stereopsis, Ocular Alignment, and Cover Testing” for Residents, 9/14.

10/2017 Lecture, “Binocular Vision and Eye Tracking “for Residents, 10/5

2/2018 Grand Rounds Lecture, “Why Some Patterns of Visual Field Loss from Occipital Stroke are

Common and Others are Rare”, Department of Ophthalmology, 2/22.

3/2018 Lecture, Diagnosis of Ocular Motility Disorders” for Ophthalmology Residents, 3/16.

4/2018 Direct ophthalmoscopy training session for first year medical students 4/17.

Informal Teaching:

2017-18 Wednesday Afternoons - Supervise Ophthalmology and Neurology Resident while they

examine patients in my Neuro-Ophthalmology Practice.

2017-18 Tuesday Afternoons - Supervise Ophthalmology Residents while they examine patients in my

Pediatric Ophthalmology Practice.

2017-18 Supervise Ophthalmology Residents during surgery on Monday mornings.

2017-18 Mentoring PhD students

Total Hours Teaching:

Neuroscience 201C 15 Hours

Informal Hospital Consultations 75 Hours

Surgical Teaching 50 Hours

Teaching Resident During My Monday & Wednesday Clinics 100 Hours

Preparation and Delivery of Other Lectures at UCSF 20 Hours

Mentoring PhD students 10 Hours

Total: 270 Hours

32

Total Annual Teaching Hours Current Year = 270 Hours

Total Hours of Teaching Anticipated For Next Year = 300 Hours

Medical Students on Neuro-Ophthalmology Service:

Aug 1991 Tamela A. Moody, Fourth Year Student, UCSF. Supervised during a one month

Elective in Clinical Neuro-Ophthalmology

June-Aug 1995 Hratch D. Kourouyan, First Year Student, UCSF. Supervised during a 10 week

Summer Laboratory Research Project

June-July 1997 Kristina Tarczy-Hornoch PhD, Fourth Year Student, UCSF. Supervised during a two

month elective in Clinical Neuro-Ophthalmology

July-August 1999 Victor D. Pegado, Fourth Year Student, University of Toronto, Canada. Supervised

during a 5 week elective in Clinical Neuro-Ophthalmology

July-August 2002 Diamond Tam, Fourth Year Student, University of Dublin, Ireland. Supervised during

a 7 week elective in Clinical Neuro-Ophthalmology

June-July 2006 Amy Delpolyi, MD-PhD Student, UCSF. Supervised during a 6 week elective in

Neuro-Ophthalmology

July 2007 Kimberly Winges, Fourth Year Student, Medical College of New York. Supervised

during a 4 week elective in Ophthalmology.

Oct 2013 Meredith Greer, Fourth Year Student, U.T. San Antonio.

June-Aug 2011 Matthew Tran, UC Berkeley undergraduate, supervised during summer research

project.

September 2014 Lynn Sun MD PhD, Loyola University 4th

year medical student.

August 2016 Victoria Yan, Mt. Holyoke student, worked in lab for 2 weeks.

July-August 2017 Kimberly Tang, UC Berkeley student worked in lab for summer.

August 2017 Matthew Yan, Boston College student, in lab for 1 week.

Medical Students Participating in Neuro-Ophthalmology Clinic: Allison Y. Iwaoka-Scott (April 2007),

33

Deborah Kuo (May 2007), Ehrine Manzana (May 2007), Lilith Judd (September 2007), Julie Stein (March

2008), Teve Cage (Dec 2008), Joanna Mandell (Jan 2009), Hannah Boal (Feb 2009), Geoffrey Krause (Jan

2010), Aubrey Gilbert (March 2010), Anne Fang (June 2010), Peter Abdulmelik (Sept. 2009), Taylor Clarke

(March 2011), Molly Lubin (Sept. 2012), Julia Shalen (August 2013), Renatta Knox (Oct 2013), Jo Jo Wang

(Feb 2014), Caroline Tong (March 2014), Joline Fan (March 2014), Juan Fernandez (Feb 2017), Nausheen

Mahmood (Aug. 2017), Siena Duarte (Sept. 2017), Leah Conant (Jan 2018), Roger Chang (Jan 2018),

Phoebe Johnson-Black (Feb. 2018).

UCSF Ophthalmology Residents on Neuro-Ophthalmology Service:

(1990-now) Eleanor Becker MD, Ronald Melles MD, Gail Royal MD, Thomas Wohl MD, Patrick Bulter

MD, Andrew Calman MD PhD, Janet Chan MD, Lisa Hake MD, Paul Langer MD, Susan Connolly MD,

Susan Carter MD, Agnes Huang MD, Ma'an Nasir MD, William Chang MD, Pierre Alfred MD, Jorge

Arroyo MD, Emmett Cunningham MD PhD, Daniel Foreman MD, Joseph McCann MD PhD, Ella

Faktorovich MD, Gustavo Gonzales MD PhD, Michael Jumper MD, Robert Lee MD, Matthew Jones MD,

Scott Sykes MD, Jeanne Smith MD, Jocelyn del Carmen MD, Timothy Scott MD, Shan Lin MD, Thomas

McDonald MD, Terri-Diann Pickering MD, Jennifer Smith MD, Stephen Stechschulte MD, Susan Pepin

MD, Ajita Grewal MD, Kristin Nesburn MD, Jacque Duncan MD, Nicolas Batra MD, Paul Chen MD,

Velimir Petrovic MD, Sharon Solomon MD, Ayman Naseri MD, Stephanie Phan MD, John F. Warren MD,

Laura Fine MD, Lillian Lee MD, Michelle Blumer MD, Athear Alrawi MD, Michael Hee, MD, W. Priscilla

Lee, MD, Anthony Poothullil MD, Patricia Tsai MD, Janet Lee MD, Jay Stewart MD, Janie Ho MD,

Jyotsom Ganatra MD, Michelle Nee, MD, David Hollander MD, Poorab Sangani MD, Richard Alvarado

MD, Robin Vora MD, Marsha Cheung MD, Scott Lee, MD, Jennifer Diehn MD, Brandon Lujan MD, Reza

Vagefi MD, Diamond Tam MD. Anthony Agadzi MD, Tina Rutar MD, Bryan Winn MD, Mark Pennesi MD,

PhD, Julie A. Chen MD, Jessie B. Biebesheimer MD, Alejandra de Alba-Campamones MD, MPH, Michael

K. Yoon MD, Michelle Trager MD, Shelley Day MD, Ying Han MD PhD, Soraya Rofagha MD, Isabella

Phan MD, Phoebe Lin MD PhD, Cyril Dalman MD PhD, Jennifer Taylor MD, Marielle Young MD, Juanita

Bryant MD, Alison Skalet MD, Charles Lin MD, Brett Shapiro MD, Joseph Martel MD, Jason Ruggiero

MD, Daniel Greninger MD, Sara Haug MD, PhD, Jonathan Greene MD, Aiyin Chen MD, Michael Chen

MD, Scott McClintic MD, Justin Baynham MD, Julie Schallhorn MD, Michael Seider MD, Ashleigh

Levison MD, Michael Geske, MD, Shivali Menda MD, Ian Gorovoy MD, Noelle Layer MD, Allison Loh

MD, Euna Koo MD, Shilpa Desai MD, Sundeep Kasi MD, Qi Cui MD, Debbie Kuo MD, Maanasa Indaram

MD, Sarah DeParis MD, Irina de la Huerta MD PhD. END OF PEDS/NEURO RESIDENT. Kareem

Moussa MD, Julius Oatts MD, Joey Hsia MD, Michelle Peng MD, Eugene Lowry MD, Catherine Sun MD,

Frank Brodie MD, Kristin Hirabayashi MD, Michael Ryan, MD, Quinn Wang MD, Megan Law MD, David

Ashraf MD, Mingy Kang MD, Francis Wu MD, Lesley Everett MD PhD, Jonathan Li MD.

UCSF Neurology Residents on Neuro-Ophthalmology Service:

May-June 1995 Chadwick Christine MD, March 1996 Daniel D. Mikol MD, Sept 1996 Dane Chetkovich

MD, Jan-May 1997 Mark Diamond MD, May-June 1997 Bruce McCarthy MD, September 1997 Ealon

Joelson MD, May 1998 Catherine E. Lomen-Hoerth MD, October 1998 Andrew H. Ahn MD, Dec 1998-Jan

1999 Nerissa U. Ko MD, Sept 1999 Breanna M. Ruthrauff MD, January 2000 Charlotte J. Sumner MD,

February 2000 Nicole Calakis MD, July 2000 Sarah Smith MD, August 2000 Timothy Miller MD, October

2000 Jacob Elkins MD,August 2001 Joseph English, MD, September 2001 Jeffrey Ralph MD, October 2001

Erik Roberson MD, November 2001 Maarten Lansberg MD, May 2002 Tammy Tsuchida MD, Pediatric

34

Neurology Fellow, UCSF, July 2002 Abraham Cheung MD, August 2002 Aaron Lewis MD, September

2002 Anita Koshy MD, October 2002 Aimee Kao MD, November 2002 Anthony Chen MD, July 2003 Gil

D. Rabinovici MD, August 2003 Ari J. Green MD, September 2003 Yoon-Hee Cha MD, October 2003

Ken Nakamura MD, November 2003 Leslie Gillum MD, December 2003 Andrew Josephson MD, July 2004

Nobl Barazangi MD, August 2004 Huidy Shu MD, Sept 2004 Jennifer Clark MD, Oct. 2004, Kathleen

Poston, MD, July 2005 Heather Hines MD, Oct. 2005 Matthew Harms MD, Nov. 2005 Susannah Brock

MD, Kyle Steinman MD Jan 2006, Dina Dubal MD May 2006, Brian Berman MD July 2006, Sabine Mueller

MD October 2006, Christine Fox MD November 2006, Emily Ho MD December 2006, Geoffrey Kerchner

MD PhD March 2007, Manu Hegde MD August 2007, Derek R. Johnson MD September 2007. Carson

Lawall MD October 2007, Karen DaSilva MD February 2008, John Neely MD, PhD March 2008, Vanja

Douglass MD April 2008, Amy Lee MD May 2008, Josiah Ambrose MD Oct 2008, Brandon Zielinski MD

(fellow) Oct. 2008, Michael Ward MD PhD April 2009, Sarah Shalev MD June 2009, Barak Bar MD,

August 2009, Jeffrey Gelfand MD, August 2009, Robert White MD PhD Sept. 2009, Mercedes Paredes MD

PhD (Nov. 2009), Jacqueline Marcus (Jan 2010), Yana Kriseman MD (March 2010), Sami Barmada MD,

PhD (April 2010), Jim Maas MD (May 2010), Audrey Brumbeck MD PhD (June 2010), Erik Johnson MD,

PhD (July 2010), Maulik Shah MD (August 2010), Amy Tso MD (August 2010), Amar Dhand MD DPhil

(August 2010), Aaron Grossman MD, PhD (October 2010), Raquel Gardner MD (Nov 2010), Sarah Kempe-

Mehl MD (Dec. 2010), Sunil Sheth MD (Feb 2011), Kelly Mills MD (March 2011), Molly Burnett MD

(April 2011), Maranatha Ayodele MD (June 2011), Laura Koehn MD (September 2011), Neel Singhal MD

PhD (October 2011), Kate Crozier MD (Nov 2011), Kathryn Kvam MD (January 2011), Rachel Paul MD

(April 2012), Maggie Waung MD PhD (May 2012), Shannon Beres MD (July 2012), Mark Burish MD PhD

(Sept 2012), Lara Zimmerman MD (January 2013), Shahed Toossi MD (February 2013), Maxime Baud MD

PhD (March 2013), Tristan Sands MD PhD (April 2013), Maura Madou MD (June 2013), Philip Larimer

MD PhD (July 2013), Liza Ashbrook MD (Sept. 2013), Nathaniel Robbins MD (October 2013), Elizabeth

Kim MD (November 2013), Brian Yurgionas MD (Jan 2013), Ethan Brown MD PhD (Feb 2013), Zachary

Threlkeld (April 2014), Jennifer Martelle MD (May 2014), Jennifer Dwyer MD PhD (June 2013), Cathra

Halabi MD (July 2014), Niraj Shanbhag MD, PhD (July 2014), Sherman Jia MD (August 2014), Jessica

Deleon MD (October 2014), Nicole Rosendale MD (November 2014), Katherine Hamilton MD (February

2015), David Young MD PhD (March 2015), Scott Caganap MD (April 2015), Shahed Toossi MD (April

2015), Nancy Bush MD PhD (May 2015), Ryan Shubert MD (July 2015), Natalie Witek MD (August 2015),

Andrew Romeo MD (August 2015), Elan Guterman MD (Sept. 2015), Kaitlin Greene MD (December 2015),

Claire Clelland MD (Jan 2015). Besim Uzgil MD PhD (January 2016), Jonathan Kleen MD PhD (Feb 2016),

Arturo Montaño MD (March 2015), Kevin Keenan MD (April 2015), Jasmin Dao MD PhD (May 2015),

Christopher McGraw MD PhD (July 2015), Paul Sampognaro MD (July 2016), Alexander Yoo MD (August

2016), Armen Moughamian MD PhD (August 2016) , Thomas Ragole MD (September 2016), Ivy Nguyen

MD (October 2016), Caroline Crooms MD (October 2016), Julian Thomas MD (Nov. 2016), Juliet Morgan

MD (Dec 2016), Elif Sozmen MD PhD (Jan 2017), Sharon Wietstock MD (Jan 2017), Collin Kreble MD

PhD (Feb. 2017), Patrick Hullett MD PhD (February 2017), Sara LaHue (March 2017), Joline Fan MD

(March 2017), Sasha Gupta MD (April 2017), Jeremy Tanner MD (April 2017), Emily Harrington MD PhD

(July 2017), Joe Sanford MD (Dec 2017), Tessa Juhong MD PhD (Jan 2018), Lauren Patrick MD (Jan 2018),

Mauro Caffarelli MD (Feb 2019), Hannah Kirsch MD (March 2018), Julian Motzkin MD PhD (April 2018).

Residents or Medical Students on Pediatric Ophthalmology Service: Tai Lockspeiser, MD March 2009,

Susy Jeng MD April 2010. Melissa Catenacci MD (Oct 2010), Elizabeth Shen (Nov. 2010)

35

Other Neurology Residents on Neuro-Ophthalmology Service:

July-Sept 1991 Edwin G. Garcia MD, Neurology Resident, University of Nebraska. Supervised during a 3-

month Neuro-Ophthalmology Elective (Jointly with Dr. William Hoyt).

November 1997 Ted M. Burns MD, Neurology Resident, University of Virginia. Supervised during a 1

month Neuro-Ophthalmology Elective. George Nunes MD (CPMC). June 2009.

Graduate Students:

Sept – Dec 1998 Robin D. LeWinter, Neuroscience Graduate Student, UCSF. Supervised during a 3

month rotation elective in my laboratory.

Jan – March 2003 Melville Wohlgemuth, Neuroscience Graduate Student, UCSF. Supervised during a

3 month rotation elective in my laboratory

April-June 2003 Ken Park, Neuroscience Graduate Student, UCSF. Supervised during a

3 month rotation elective in my laboratory

Member of Preliminary Oral Exam Committee or Thesis Committee for Graduate Students:

5/2000 Justin Gardner, Lisberger Lab UCB/UCSF Bioengineering Graduate Group

5/2000 Anne Churchland, Lisberger Lab Neuroscience Program

8/2000 Michael Orger, Baier Lab Neuroscience Program

12/2000 Stephen V. David, Gallant Lab UCB/UCSF Bioengineering Graduate Group

6/2003 David Schoppik, Lisberger Lab Neuroscience Program

8/2004 Amy Depolyi, Mucke Lab Neuroscience Program

9/2004-2009 Melville Wolgemuth, Brainard Lab Neuroscience Program

5/2005-2009 Matt Caywood, Stryker Lab Neuroscience Program

3/2006-2008 Leah McGuire, Sabes Lab Neuroscience Program

8/2005-2007 Melinda Owens, Stryker Lab Neuroscience Program

10/2008 Peter Li, Schnapf Lab Neuroscience Program

9/2009 Johnny Tam, Roorda Lab UCB Optometry Program

2014- Joseph Huff, Usrey Lab UC Davis Neuroscience Program

2016 - Rachel Care, Dunn Lab Neuroscience Program

Fellows:

June 1998 Daniel L. Adams PhD. Joined laboratory as a post-doctoral fellow.

September 1999 Lawrence Sincich PhD. Joined laboratory as a post-doctoral fellow. Dr. Sincich was

supported by an NRSA grant, F32 EY13676 entitled “V1 to V2 Projections in Normal

Vision and Amblyopia”. Now an Assistant Professor at the University of Alabama

36

March 2003 John Economides PhD. Joined laboratory as a post-doctoral fellow. Dr. Economides

was supported by an NRSA grant, F32 EY15343 entitled “Neural Basis of Visual

Suppression in Strabismics”.

July 2005-June 2006 Y. Joyce Liao MD PhD. Clinical Fellow in Neuro-Ophthalmology

Jan 2007–June 2008 Thomas N. Hwang MD Clinical Fellow in Neuro-Ophthalmology

May 2009–July 2009 Pai Huei Peng MD Clinical Fellow from Tapei, Taiwan

July 2010–June 2011 Michael K. Yoon MD Clinical Fellow in Neuro-Ophthalmology

July 2011–June 2012 Sungeun Kyung MD PhD Clinical Fellow in Neuro-Ophthalmology

March 2018 – March 2019 YoungWoo Sui MD PhD Clinical Fellow in Neuro-Ophthalmology

MENTORING: I am mentoring two post-doctoral fellows in my laboratory. I am responsible for the

successful development of their careers. I have also performed informal mentoring for graduate students in

the Neuroscience program, medical students, ophthalmology residents, and neurology residents.

ORIGINAL PEER-REVIEWED PUBLICATIONS:

Horton, J.C. and Hedley-Whyte, E.T., Protein movement across the blood-brain barrier in hypervolemia,

Brain Research, 169:610-614, 1979.

*Horton, J.C., Greenwood, M.M., and Hubel, D.H., Non-retinotopic arrangement of fibers in cat optic nerve,

Nature, 282:720-722, 1979.

*Horton, J.C. and Hubel, D.H., Regular patchy distribution of cytochrome oxidase staining in primary visual

cortex of macaque monkey, Nature, 292:762-764, 1981.

*Horton, J.C., Cytochrome oxidase patches: a new cytoarchitectonic feature of monkey visual cortex, Phil.

Trans. R. Soc. (Lond.) B, 304:199-253, 1984.

*Horton, J.C. and Hedley-Whyte, E.T., Mapping of cytochrome oxidase patches and ocular dominance

columns in human visual cortex, Phil. Trans. R. Soc. (Lond.) B, 304:255-272, 1984.

Brunquell, P.J., Papale, J.H., Horton, J.C., Williams, R.S., Zgrabik, M.J., Albert, D.M., Hedley-Whyte, E.T.,

Sex-linked hereditary bilateral anophthalmos, Arch. Ophthalmology, 102:108-113, 1984.

*Horton, J.C. and Sherk, H., Receptive field properties in the cat's lateral geniculate nucleus in the absence of

on-center retinal input, J. Neuroscience, 4:374-380, 1984.

*Sherk, H. and Horton, J.C., Receptive field properties in the cat's area 17 in the absence of on-center

geniculate input, J. Neuroscience, 4:381-393, 1984.

37

Horton, J.C., The Behrhorst Foundation at 25 years: a report from Chimaltenango, Guatemala, N. Eng. J.

Med., 316:1666-1669, 1987.

*Horton, J.C., Chambers, W.A., Lyons, S. L., Adams, R.D., Kjellberg, R. N., Pregnancy and the risk of

hemorrhage from cerebral arteriovenous malformation. Neurosurgery, 27:867-872, 1990.

Horton, J.C., Mathers, W.D., Zimmerman, L.E., Pyogenic granuloma of the palpebral conjunctiva associated

with contact lens wear. Cornea, 9(4):359-361, 1990.

*Horton, J.C., Dagi, L.R., McCrane, E.P., de Monasterio, F.M., Arrangement of ocular dominance columns

in human visual cortex. Arch. Ophthalmology, 108:1025-1031, 1990.

Horton, J.C., Landau, K., Maeder, P., Hoyt, W.F., Magnetic resonance imaging of the human lateral

geniculate body. Arch. Neurology, 47:1201-1206, 1990.

Landau, K., Horton, J.C., Hoyt, W.F., Wilson, C.B., Aneurysm mimicking intracranial growth of optic nerve

sheath meningioma. J. Clin. Neuro-Ophthalmology, 10:185-187, 1990.

Horton, J.C., Tsai, R.K., Truwit, C.L., Hoyt, W.F., Superior oblique muscle atrophy in acquired trochlear

nerve palsy imaged by magnetic resonance. Am. J. Ophthalmology, 110:315-316, 1990.

Horton, J.C., Harsh, G.R., Fisher, J.W., Hoyt, W.F., Von Hippel-Lindau disease and erythrocytosis:

radioimmunoassay of erythropoietin in cyst fluid from a brainstem hemangioblastoma. Neurology, 41:753-

754, 1991.

Horton, J.C., Wilson, C.B., Hoyt, W.F., Herpes reactivation and ophthalmoplegia from pituitary adenoma

invading the cavernous sinus. Arch. Ophthalmology, 109:323-324, 1991.

*Horton, J.C. and Hoyt, W.F., The representation of the visual field in striate cortex: A revision of the classic

Holmes map. Arch. Ophthalmology, 109:816-824, 1991.

*Horton, J.C. and Hoyt, W.F., Quadrantic visual field defects: a hallmark of lesions in extrastriate (V2/V3)

cortex. Brain, 114:1703-1718, 1991.

Wohl, T.A., Kattah, J.C., Kolsky, M.P., Alper M.G., Horton, J.C., Hemianopia from occipital lobe abscess

after dental care. Am. J. Ophthalmology, 112:689-694, 1991.

Rando, T.A., Horton, J.C., Layzer, R.B., Wolfram syndrome: evidence of a diffuse neurodegenerative disease

by magnetic resonance imaging. Neurology, 42:1220-1224, 1992.

Horton, J.C., Garcia, E.G., Becker, E.K., Magnetic resonance imaging of leukemic invasion of the optic

nerve Arch. Ophthalmology, 110:1207-1208, 1992.

*Horton, J.C., Seiff, S.R., Pitts, L.H., Weinstein, P.R., Rosenblum, M.L., Hoyt, W.F., Decompression of the

optic nerve sheath for vision-threatening papilledema caused by dural sinus occlusion. Neurosurgery, 31:203-

212, 1992.

38

Moody, T.A., Irvine, A.R., Cahn, P.H., Susac, J.O., Horton, J.C., Sudden visual field constriction associated

with optic disc drusen. J. Clinical Neuro-Ophthalmol, 13:8-13, 1993.

Horton, J.C., Langer, P.D., Turner, G.E., Free air in the cavernous sinus as an incidental finding. J. Clinical

Neuro-Ophthalmol, 13:50-53, 1993.

Lyons, C.J., Wilson, C.B., Horton, J.C., Association between meningioma and Cowden's Disease.

Neurology, 43:1436-1437, 1993.

*Horton, J.C. and Stryker, M.P., Amblyopia induced by anisometropia without shrinkage of ocular

dominance columns in human striate cortex. Proc. Natl Acad. Sci., 90:5494-5498, 1993.

*Connolly, S.E., Gordon, K.B., and Horton, J.C., Salvage of vision after hypotension-induced ischemic optic

neuropathy. Am. J. Ophthalmology, 117:235-242, 1994.

Horton, J.C. and Fishman, R.A., Neurovisual findings in the syndrome of spontaneous intracranial

hypotension from dural cerebrospinal fluid leak. Ophthalmology, 101:244-251, 1994.

Horton, J.C., Embolic cilioretinal artery occlusion: Implications for the etiology of anterior ischemic optic

neuropathy. Retina, 15:441-444, 1995.

Arroyo, J.G., and Horton, J.C., Acute painful pupil-involving third nerve palsy in chronic inflammatory

demyelinating polyneuropathy. Neurology, 45:846-847, 1995.

Horton, J.C., Hoyt, W.F., Foreman, D.S., and Cohen, J.A., Confirmation by magnetic resonance imaging of

optic nerve injury after retrobulbar anesthesia. Arch. Ophthalmology, 114:351-353, 1996.

Jumper, J.M., and Horton, J.C., Central retinal artery occlusion after manipulation of the neck by a

chiropractor. Am. J. Ophthalmology, 121:321-322, 1996.

*Horton, J.C., and Hocking, D.R., An adult-like pattern of ocular dominance columns in striate cortex of

newborn monkeys prior to visual experience. J. Neuroscience, 16:1789-1805, 1996.

*Horton, J.C., and Hocking, D.R., Pattern of ocular dominance columns in human striate cortex in strabismic

amblyopia. Visual Neuroscience, 13:787-795, 1996.

Horton, J.C., and Hocking, D.R., Anatomical demonstration of ocular dominance columns in striate cortex of

the squirrel monkey. J. Neuroscience, 16:5510-5522, 1996.

*Horton, J.C., and Hocking, D.R., Intrinsic variability of ocular dominance column periodicity in normal

macaque monkeys. J. Neuroscience, 16:7228-7239, 1996.

Horton, J.C., and Jones, M.R., Warning on inaccurate Rosenbaum cards for testing near vision. Survey of

Ophthalmology, 42:169-174, 1997.

Horton, J.C., and Hocking, D.R., Myelin patterns in V1 and V2 of normal and monocularly enucleated

39

monkeys. Cerebral Cortex, 7:166-177, 1997.

Kourouyan, H.D., and Horton, J.C., Transneuronal retinal input to the primate Edinger-Westphal nucleus. J.

Comp. Neurology, 381:68-80, 1997.

Horton, J.C., Hocking, D.R., and Kiorpes, L., Pattern of ocular dominance columns and cytochrome oxidase

activity in a macaque monkey with naturally occurring anisometropic amblyopia. Visual Neuroscience,

14:681-689, 1997.

*Horton, J.C., and Hocking, D.R., Timing of the critical period for plasticity of ocular dominance columns in

macaque striate cortex. J. Neuroscience, 17:3684-3709, 1997.

Sykes, S.O., and Horton, J.C., Steroid-responsive retinal vasculitis with a frosted branch appearance in

Crohn's Disease. Retina, 17:451-454, 1997.

Horton, J.C., Wilbrand's Knee of the primate optic chiasm is an artefact of monocular enucleation.

Transactions American Ophthalmological Soc, XCV:579-609, 1997.

Horton, J.C., and Hocking, D.R., Effect of early monocular enucleation upon ocular dominance columns and

cytochrome oxidase activity in monkey and human visual cortex. Visual Neuroscience, 15:289-303, 1998.

Cunningham, E.T., Seiff, S.R., Berger, T.G., Lizotte, P.E., Howes, E.L., and Horton, J.C., Intraocular

coccidioidomycosis diagnosed by skin biopsy. Arch Ophthalmology, 116:674-677, 1998.

*Horton, J.C., and Hocking, D.R., Monocular core zones and binocular border strips in primate striate cortex

revealed by the contrasting effects of enucleation, eyelid suture, and retinal laser lesions upon cytochrome

oxidase activity. J. Neuroscience, 18:5433-5455, 1998.

Horton, J.C. and Trobe, J.D., Akinetopsia from nefazodone toxicity. Am. J. Ophthalmology, 128:530-531,

1999.

*Horton, J.C., Hocking, D.R., and Adams, D.L., Metabolic mapping of suppression scotomas in striate

cortex of macaques with experimental strabismus. J. Neuroscience , 19:7111-7129, 1999.

Horton, J.C., Hocking, D.R., and Adams, D.L., Rapid identification of ocular dominance columns using

cytochrome oxidase, Zif268, and darkfield microscopy. Visual Neuroscience, 17:495-508, 2000.

Horton, J.C. and Adams, D.L., The cortical representation of shadows cast by retinal blood vessels.

Transactions American Ophthalmological Soc. XCVIII:33-39, 2000.

Crair, M.C., Horton, J.C., Antonini, A., and Stryker, M.P., Emergence of ocular dominance columns in cat

visual cortex by 2 weeks of age. J. Comp. Neurology, 430:235-249, 2001.

Naseri, A., Blumenkranz, M.S., Horton, J.C., Terson’s Syndrome after epidural saline injection. Neurology,

57:364, 2001.

40

*Sincich, L.C. and Horton, J.C., Divided by cytochrome oxidase: a map of the projections from V1 to V2 in

macaques. Science, 295:1734-1737, 2002.

Sincich, L.C. and Horton, J.C., Pale cytochrome oxidase stripes in V2 receive the richest projection from

macaque striate cortex. J. Comp. Neurology, 447:18-33, 2002.

Horton, J.C., Mistaken treatment of anterior ischemic optic neuropathy with interferon beta-1a, Annals of

Neurology, 52:129, 2002.

Sincich, L.C. and Horton, J.C., An albino-like decussation error in the optic chiasm revealed by anomalous

ocular dominance columns. Visual Neuroscience, 19:541-545, 2002

*Adams, D.L. and Horton, J.C., Shadows cast by retinal blood vessels mapped in primary visual cortex.

Science, 298:572-576, 2002.

*Adams, D.L. and Horton, J.C., Capricious expression of cortical columns in the primate brain, Nature

Neuroscience, 6:113-114, 2003.

Adams, D.L. and Horton, J.C., A precise retinotopic map of primate striate cortex generated from the

representation of angioscotomas. J. Neuroscience, 23:3771-3789, 2003.

Adams, D.L. and Horton, J.C., The representation of retinal blood vessels in primate striate cortex . J.

Neuroscience, 23:5984-5997, 2003.

Newman-Toker, D.E., Horton, J.C., Lessell, S, Recurrent visual loss in Leber’s hereditary optic neuropathy.

Arch Ophthalmology, 121:288-290, 2003.

Sincich, L.C. and Horton, J.C., Independent projection streams from macaque striate cortex to the second

visual area and middle temporal area. J. Neuroscience, 23:5684-5692, 2003.

Sincich, L.C., Adams, D.L., and Horton, J.C., Complete flatmounting of the macaque cerebral cortex. Visual

Neuroscience, 20:663-686, 2003.

Binder, D.K., Horton J.C., Lawton, M.T., McDermott, M.W., Idiopathic intracranial hypertension.

Neurosurgery, 54:538-551, 2004.

*Sincich, L.C., Park, K.V., Wohlgemuth, M.J., Horton, J.C., Bypassing V1: a direct geniculate input to area

MT, Nature Neuroscience, 7:1123-8, 2004.

Economides, J.R. and Horton, J.C., Labeling of cytochrome oxidase patches in intact flatmounts of striate

cortex. J. Neuroscience Methods, 149:1-6, 2005.

Rutar, T., Zwick, O.M., Cockerham, K.P., Horton, J.C., Bilateral blindness from orbital cellulitis caused by

community-acquired methicillin-resistant Staphylococcus aureus. American J. of Ophthalmology, 140:740-

742, 2005.

41

Economides J.R. and Horton, J.C., Eye movement abnormalities in stiff person syndrome. Neurology,

65:1462-1467, 2005.

Sincich, L.C. and Horton, J.C., Input to V2 thin stripes arises from V1 cytochrome oxidase patches. J.

Neuroscience, 25:10087-10093, 2005.

*Adams, D.L. and Horton, J.C., Monocular cells without ocular dominance columns, J. Neurophysiology,

96:2253-2264, 2006.

Adams, D.L. and Horton, J.C., Ocular dominance columns in strabismus, Visual Neuroscience, 23:795-805,

2006.

Vagefi, M.R., Larson, D.A., Horton, J.C., Optic nerve sheath meningioma: visual improvement during

radiation treatment, American J. Ophthalmology, 142:343-344, 2006.

*Sincich, L.C., Adams, D.L., Economides, J.R., Horton, J.C., Transmission of spike trains at the

retinogeniculate synapse, J. Neuroscience, 27:2683-2692, 2007.

Sincich, L.C., Jocson C. M., and Horton, J.C., Neurons in V1 patch columns project to V2 thin stripes,

Cerebral Cortex, 17:935-941, 2007.

Adams, D.L., Economides, J.R., Horton, J.C., A biocompatible titanium headpost for stabilizing behaving

macaques. J. Neurophysiology, 98:993-1001, 2007.

Liao, Y.J., Dillon, W.P., Chin, C.T., McDermott, M.W., Horton, J.C., Intracranial hypotension caused by

leakage of cerebrospinal fluid from the thecal sac after lumboperitoneal shunt, J. Neurosurgery, 107:173-7,

2007.

Wynn, B.J., Liao, Y.J., and Horton, J.C., Intracranial pressure returns to normal about a month after stopping

tetracycline antibiotics, Arch. Ophthalmology, 125:1137-8, 2007.

*Adams, D.L., Sincich, LC, and Horton, J.C., The complete pattern of ocular dominance columns in human

primary visual cortex, J. Neuroscience, 27:10391-10403, 2007.

*Economides, J.R., Adams, D.L., Jocson, C., M., Horton, J.C., Ocular motor behavior in macaques with

surgical exotropia, J. Neurophysiology, 98:3411-3422, 2007.

Carandini, M., Horton, J.C., Sincich, L.C., Thalamic filtering of retinal spike trains by postsynaptic

summation, J. Vision , 7(14):20, 1-11, 2007.

De Alba, A.G., Larson, D.A., Horton, J.C., Immediate shrinkage of optociliary shunt vessels following

fractionated external beam radiation for optic nerve sheath meningioma, American J. Neuroradiology,

29:1360-1362, 2008.

Han, Y., McCulley, T.J., Horton, J.C., No correlation between intraocular pressure and intracranial pressure,

Annals of Neurology, 64:221-224, 2008.

42

*Sincich, L.C., Horton, J.C., Sharpee, T.O., Preserving information in neural transmission, J. Neuroscience,

29:6207-6216, 2009.

*Sincich, L.C., Zhang, Y., Tiruveedhula, P., Horton, J.C., Roorda, A., Resolving single cone inputs to visual

receptive fields. Nature Neuroscience, 12:967-969, 2009.

Sincich, L.C., Jocson C. M., and Horton, J.C., V1 interpatch projections to V2 thick stripes and pale stripes.

J. Neuroscience, 30:6963-6974, 2010.

Horton, J.C., Yoon, M.K., Carvalho, M.D, McLeod, S.D., Polymerase chain reaction confirmed by

immunohistochemistry: a two-pronged diagnostic approach in endophthalmitis. Acta Ophthalmologica,

89:301-2, 2011.

Yoon, M.K., Horton, J.C., McCulley, T.J., Facial nerve injury: a complication of superficial temporal artery

biopsy. Amer. J. Ophthalmology, 152:251-255, 2011.

Hwang, T.N., Rofagha, S., McDermott, M.W., Hoyt, W.F., Horton, J.C., McCulley, T.J., Sunken eyes,

sagging brain syndrome: bilateral enophthalmos from chronic intracranial hypotension. Ophthalmology,

118:2286-2295, 2011.

Adams, D.L., Economides, J.R., Jocson, C.M., Parker, J, and Horton, J.C., A watertight acrylic-free titanium

recording chamber for electrophysiology in behaving monkeys. J. Neurophysiology, 106:1581-90, 2011.

Gilbert, A.L., Dillon W.P., Horton, J.C., Blepharospasm in a patient with pontine capillary telangiectasia,

Ophthal Plast Reconstr Surg, 28: e92-93, 2012.

*Economides, J.R., Sincich, L.C., Adams, D.L., Horton, J.C., Orientation tuning of cytochrome oxidase

patches in macaque primary visual cortex. Nature Neuroscience, 14:1574-1580, 2011.

Yoon, M.K., Economides, J.R., Horton, J.C., Extraocular muscle dynamics in diplopia from enophthalmos.

Strabismus, 19:142-146, 2011.

*Sincich, L.C., Jocson C. M., and Horton, J.C., Neuronal projections from V1 to V2 in amblyopia. J.

Neuroscience, 32:2648-2656, 2012.

Kyung, S.E., Yoon, M.K., Crawford, J.B, Horton, J.C., Florid arteritis confined to a single branch of the

superficial temporal artery. Arch Ophthalmology, 130:1347-1348, 2012.

*Economides, J.R., Adams, D.L., Horton, J.C., Perception via the deviated eye in strabismus. J.

Neuroscience, 32:10286-10295, 2012.

*Adams, D.L., Economides, J.R., Sincich, L.C., Horton, J.C., Cortical metabolic activity matches the pattern

of visual suppression in strabismus. J. Neuroscience, 33:3752-3759, 2013.

Yoon, M.K., Parsa, A.T., Horton, J.C., Skull thickening, paranasal sinus expansion, and sella turcica

shrinkage from chronic intracranial hypotension. J. Neurosurgery:Pediatrics, 11:667-672, 2013.

43

Lujan, B.J. and Horton, J.C., Microcysts in the inner nuclear layer from optic atrophy are caused by

retrograde trans-synaptic degeneration combined with vitreous traction on the retinal surface. Brain doi:

10.1093/brain/awt154, 2013.

Kyung, S.E., Botelho, J.V., Horton, J.C., Enlargement of the sella turcica in pseudotumor cerebri. J.

Neurosurgery, 120:538-542, 2014.

*Economides, J.R., Adams, D.L., Horton, J.C., Eye choice for target acquisition in alternating strabismus. J.

Neuroscience, 34:14578-14588, 2014.

Sun, L.W. and Horton, J.C., Papilledema in puberty. Clinical Pediatrics, 54:504-506, 2014.

Chan, L.T., Lynch, W. De May, M. Horton, J.C., Miller, BL., Rabinovici, G.D., Prodromal posterior cortical

atrophy: clinical, neuropsychological, and radiological correlation. Neurocase, 21:44-55, 2015.

Desai, S.J., Lawton, M.T., McDermott, M.W., Horton, J.C., Vertical diplopia and ptosis from removal of the

orbital roof in pterional craniotomy. Ophthalmology, 122:631-638, 2015.

*Adams, D.L., Piserchia, V., Economides, J.R., Horton, J.C., Vascular supply of the cerebral cortex is

specialized for cell layers but not columns. Cerebral Cortex, 25:3673-3681, 2015.

Kyung, S.E. and Horton, J.C., Papilledema from craniosynostosis in pycnodysostosis. Pediatric Neurology,

52:128-129, 2015.

Adams, D.L., Economides, J.R., Horton, J.C., Contrasting effects of strabismic amblyopia on metabolic

activity in superficial and deep layers of striate cortex. J. Neurophysiology, 113:3337-3344, 2015.

Horton, J.C., Douglas, V.C., Cha, S., Reduced apparent diffusion coefficient in neuromyelitis optica-

associated optic neuropathy. J. Neuro-ophthalmology, 35:101-102, 2015.

Adams, D.L., Economides, J.R., Horton, J.C., Co-localization of glutamic acid decarboxylase and vesicular

GABA transporter in cytochrome oxidase patches of macaque striate cortex. Visual Neuroscience, 32:e026,

2015.

Horton, J.C. and Miller, S., Magnetic resonance imaging in epidemic adenoviral keratoconjunctivitis. JAMA

Ophthalmology, 133:960-961, 2015.

*Horton, J.C., Parker, A.B., Botelho, J.V., Duncan J.L., Spontaneous regeneration of human photoreceptor

outer segments. Scientific Reports, 5:12364, 2015.

Economides, J.R., Adams, D.L., Horton, J.C., Variability of ocular deviation in strabismus. JAMA


Adams, D.L., Economides, J.R., Horton, J.C., Cortical representation of a myopic peripapillary

Ophthalmology, 123:1494-1499, 2016.

Han, S.J., Magill, S.T., Tarapore, P.E., Horton, J.C., McDermott, M.W., Direct visualization of improved

44

optic nerve pial vascular supply following tuberculum meningioma resection. J. Neurosurgery, 125:565-569,

2016.

Guterman, E.L., Botelho, J.V., Horton, J.C., Diagnosis of Tensilon-negative ocular myasthenia by daily

selfie. J. Neuro-ophthalmology, 36:292-293, 2016.

*Economides, J.R., Adams, D.L., Horton, J.C., Normal correspondence of tectal maps for saccadic eye

movements in strabismus. J. Neurophysiology, 116:2541-2549, 2016.

Horton, J.C., Fahle, M., Mulder, T., Trauzettel-Klosinski, S., Adaptation, perceptual learning and plasticity

of brain functions, Graefe’s Archive for Clinical and Experimental Ophthalmology, 255:435-447, 2017.

*Economides, J.R., Adams, D.L., Horton, J.C., Capturing the moment of fusion loss in intermittent

exotropia, Ophthalmology, 124:496-504, 2017.

Horton, J.C. and Barkovich, A.J., Bilateral optic disc pits with posterior pituitary ectopia. J. Neuro-

ophthalmology, 37:401-2, 2017.

Adams, D.L., Economides, J.R., Horton, J.C., Incomitance and eye dominance in intermittent exotropia,

Invest. Ophthalmol. Vis. Sci., 58:4049-4055, 2017.

*Economides J.R., Rapone, B.C., Adams, D.L., Horton, J.C., Normal topography and binocularity of the

superior colliculus in strabismus. J. Neuroscience, 38:173-182, 2018.

Adams, D.L., Rapone, B.C., Economides, J.R., Horton, J.C., Spontaneous reattachment of the medial rectus

after free tenotomy. J. Pediatric Ophthalmology & Strabismus (in press).

Horton, J.C. and Adams, D.L., Vascular supply of the occipital lobe explains why certain patterns of visual

field loss from embolic stroke are common and others are rare. J. Neuro-Ophthalmology (in press).

NOTE: papers in submission or preparation are not listed.

* Denotes Most Significant Publications.

PEER-REVIEWED BOOKS, REVIEWS, CHAPTERS, LETTERS

Horton, J.C., Medical Guide to the Behrhorst Foundation Hospital, Tulane University Press, 1985, pp. 1 - 61.

Horton, J.C., The Behrhorst Foundation (Letter), New Engl. J. Med., 317:1607, 1987.

Horton, J.C. and Dreizen, N.G., Ichthyosis. In: Gold, D.H. and Weingeist, T.A., eds., The Eye in Systemic

Disease, J.B. Lippincott, Philadelphia, 1990, pp. 599-603.

45

Horton, J.C., Review of: The Neurobiology of Saccadic Eye Movements, edited by R.H. Wurtz and M.E.

Goldberg. Arch. Neurol, 47:1165-1166, 1990.

Horton, J.C., and Hoyt, W.F., Alexia without agraphia (Letter), Neurology, 41:1708, 1991.

Horton, J.C., The central visual pathways. In: Hart W.M. Jr. and Moses R.A., eds., Adler's Physiology of the

Eye: Clinical Applications, C.V. Mosby Co., St. Louis, 9th

edition, pp. 728-772, 1992.

Horton, J.C., Commentary on: Scleral change in experimentally myopic monkeys, by M. Funata and T.

Tokoro. Surv. Ophthalmol, 36:320, 1992.

Horton, J.C., Commentary on: Bilateral homonymous hemianopsia due to tentorial herniation, with sparing

of central vision, by Tanaka, R. Neurosurgery, 31:790-791, 1992.

Horton, J.C., Lessons for a graduate in a battered red jeep. In: Lueke, R., ed., A New Dawn in Guatemala,

Waveland Press, Inc, Prospect Heights, pp.151-160, 1993.

Horton, J.C. and Arroyo, J.G., Oculomotor nerve palsy in chronic inflammatory demyelinating

polyneuropathy (letter). Neurology,47:306, 1996.

Horton, J.C., Commentary on: Farbdopplersonographie der Temporalarterien - eine neue Methode zur

Diagnostik der Arteriitis temporalis, by Kraft, H.E. et al. Surv. Ophthalmology, 41:271, 1996.

Horton, J.C., Disorders of the eye. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., et al., eds., Harrison's

Principles of Internal Medicine, McGraw-Hill, Inc., N.Y., 14th

edition, pp 159-172, 1997.

Horton, J.C., Visual loss and disorders of ocular motility. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., et

al., eds., Harrison's Principles of Internal Medicine Companion Handbook, McGraw-Hill, Inc., N.Y., 14th

edition, pp 47-51, 1998.

Horton, J.C., Discussion on: The puzzle of autism: an ophthalmologic contribution, by Miller, M.T.,

Stromland, K., Gilberg, C., Johansson, M., Nilsson , E. W., Transactions American Ophthalmological Soc.,

XCVI: 385-7, 1998.

Horton, J.C., Commentary on: Occipital lobe malformations: prevalence of visual field deficits and prognosis

after therapeutic intervention, by Bartolomei et al., Neurosurgery, 43:422, 1998.

Horton, J.C., Boundary disputes (Millennium Essay), Nature, 406:565, 2000.

Horton, J.C. Compression of the prechiasmatic optic nerve produces a junctional scotoma (letter). Amer. J.

Ophthalmology, 129:826-827, 2000.

Horton, J.C., Disorders of the eye. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., et al., eds., Harrison's


edition, pp 164-178, 2001.

Horton, J.C., Commentary on: Deterioration of giant cell arteritis with corticosteroid therapy by Staunton, H.,

46

et al. Surv. Ophthalmolgy, 45:359, 2001.

Horton, J.C., Critical periods in the development of the visual system. In: Baily, D.B., Bruer, J.T., Symons,

F.J., and Lichtman, J.W. (eds.), Critical Thinking About Critical Periods, Brooks Publishing, Inc., Baltimore,

MD, 2001.

Horton, J.C., Diagnosis, evaluation, and management of papilledema. In: “Concise Reviews”, On-Line

Edition of Harrison’s Principles of Internal Medicine, 2001.

Adams, D. L. and Horton, J.C., Book Review of: “Visual Disturbances following Gunshot Wounds of the

Cortical Visual Area by Tatsuji Inouye” (translated by M Glickstein & M. Fahle). In: Nature, 412:482-483,

2001.

Horton, J.C., Common disorders of the eye. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., et al., eds.,

Harrison's Principles of Internal Medicine Companion Handbook, McGraw-Hill, Inc., N.Y., 15th

edition,

Chapter 48, pp. 205-208, 2002.

Horton, J.C., Neurovisual manifestations of herpesviruses. In: Cunningham E.T. and Ohno, S., eds.,

International Ophthalmology Clinics, 42:33-41, 2002.

Horton, J.C., Acute visual loss and double vision. In: Fauci, A.S., Braunwald, E., Isselbacher, K.J., et al.,

eds., Harrison's Principles of Internal Medicine Companion Handbook, McGraw-Hill, Inc., N.Y., 15th

edition,

Chapter 10, pp. 10-45, 2002.

Horton, J. C., Ischemic optic neuropathy versus optic neuritis, New England J. Medicine, 347:2083, 2002.

Horton, J.C., Reply to “Overlap of optic neuritis and anterior ischemic optic neuropathy”. Annals of

Neurology, 53:417, 2003.

Adams, D.L. and Horton, J.C., Reply to letter “blood vessels casting a shadow”. Science 299:1983-84, 2003.

Horton, J.C, Sincich, L.C., A new foundation for the visual cortical hierarchy. In: Gazzaniga, M. ed., The

Cognitive Neurosciences, 3d edition, Chapter 17, pp. 233-243, 2004.

Horton, J.C., Book Review of: The Visual Neurosciences (edited by Chalupa L.M. and Werner J.S.). In:

American Journal of Ophthalmology, 137:976, 2004.

Horton, J.C., Disorders of the eye. In: Kasper, D.L., Fauci, A.S., Longo D.L., et al., eds., Harrison's


edition, Chapter 25, pp. 162-176, 2005.

Horton, J.C. and Adams, D.L., The cortical column: a structure without a function. Phil. Trans. R. Soc.

(Lond.) B, 360:837-862, 2005.

Sincich L.C. and Horton, J.C., The circuitry of V1 and V2: integration of color, form, and motion. Annual

Review of Neuroscience, 28:303-326, 2005.

Horton, J.C., Disappointing results from NovaVision’s visual restoration therapy. British Journal

47


Horton, J.C., Vision restoration therapy: confounded by eye movements. British Journal Ophthalmology,

89:792-794, 2005.

Horton, J.C., New Treatments for Optic Neuritis. Saudi Journal of Ophthalmology, 19:99-105, 2005.

Horton, J.C., Ocular integration in the human visual cortex. Canadian J. Ophthalmology, 41:584-593, 2006.

Horton, J.C., Visual Disturbances. In: Hauser, S.L., Josephson, S.A., English, J.D., et al., eds., Harrison’s

Neurology in Clinical Medicine. McGraw-Hill, Inc., N.Y., Chapter 11, 2006

Horton, J.C., Arteriovenous malformation of the brain. New Eng. J. Med., 357:1774-1775, 2007.



edition, Chapter 29, pp 180-195, 2008.

Adams, D.L. and Horton, J.C., Function of Striate Cortex. In: Binder, M.D., Hirokawa, N., Windhorst, U.,

(Eds.) Encyclopedia of Neuroscience. Springer-Verlag, 2008.

Horton, J.C., What is the evaluation for a homonymous hemianopia? In: Lee, A.G., Kline, L., Brazis, P. W.,

Curbside Consultations in Neuro-Ophthalmology. Slack, Inc., Thorofare, N.J., pp 139-144, 2009.

Adams, D.L. and Horton, J.C., Ocular dominance columns: enigmas and challenges. The Neuroscientist,

15:62-77, 2009.



edition, Chapter 29, pp 224-241, 2012.

Horton, J.C., Disorders of Vision. In: Hauser, S.L., Josephson, S.A., et al., eds., Harrison’s Neurology in

Clinical Medicine, McGraw-Hill, Inc., N.Y., 2d edition, 2010, Chapter 17, pp. 170-192.

Horton, J.C., Continuous intracranial pressure monitoring: a last resort in pseudotumor cerebri. J Neuro-

Ophthalmology, 31:199-201, 2011 [editorial].

Gilbert, A.L. and Horton, J.C., Superior oblique palsy from trochlear schwanomma. Amer. J.

Neuroradiology. October 2012 (Case of the Week).

Yoon, M.K., Horton, J.C., McCulley, T.J., Reply to a letter about our article: Facial nerve injury: a

complication of superficial temporal artery biopsy. Amer. J. Ophthalmology, 153:187-188, 2012.

Horton, J.C., Giants all around – apart from the squid. Nature, 488:32, 2012 [letter].

Horton, J.C., Yoon, M.K., McCulley, T.J., Brow ptosis after temporal artery biopsy. Ophthalmology,

120(6)e34, 2013 [letter].

48

Horton, J.C., Evidence from the NORDIC Trial: Acetazolamide works for pseudotumor cerebri. JAMA,

311:1618-9, 2014 [editorial].

Horton, J.C., Confusion between bitemporal hemianopia and ceco-central scotoma. J. Neuro-ophthalmology,

34:428, 2014 [letter].

Horton, J.C., In-flight emergency. Ann. Emerg. Medicine, 65:345, 2015 [letter].


Principles of Internal Medicine, McGraw-Hill, Inc., N.Y., 19th edition, Chapter 39, 2015.

Horton, J.C., What is the evaluation for a homonymous hemianopia? In: Lee, A.G., Kline, L., Brazis, P. W.,

Curbside Consultations in Neuro-Ophthalmology. Slack, Inc., Thorofare, N.J., pp 143-148, 2015.

Horton, J.C., Ganglion cell complex measurement in compressive optic neuropathy. J. Neuro-

ophthalmology, 37:13-15, 2017. [invited commentary].

MULTI-AUTHOR CLINICAL TRIAL REPORTS

The Ischemic Optic Neuropathy Decompression Trial Study Group, Optic nerve decompression surgery for

nonarteritic anterior ischemic optic neuropathy (NAION) is not effective and may be harmful. J. American.

Medical. Assoc., 273:625-632, 1995.

The Ischemic Optic Neuropathy Decompression Trial Study Group, The characteristics of patients with

nonarteritic anterior ischemic optic neuropathy eligible for the ischemic optic neuropathy decompression

trial. Arch. Ophthalmology, 114:1366-1374, 1996.

The Ischemic Optic Neuropathy Decompression Trial Study Group, The ischemic optic neuropathy

decompression trial (IONDT): Design and methods. Controlled Clinical Trials 19:276-296, 1998.

The Ischemic Optic Neuropathy Decompression Trial Study Group, The ischemic optic neuropathy

decompression trial: twenty-four month update. Arch. Ophthalmology, 118:793-798, 2000.

The Ischemic Optic Neuropathy Decompression Trial Study Group, The fellow eye in NAION: report from

the ischemic optic neuropathy decompression trial follow-up study. Am. J. Ophthalmol. 134:317-328, 2002.

The Ischemic Optic Neuropathy Decompression Trial Study Group, Surgical quality assurance in the

Ischemic Optic Neuropathy Decompression Trial (IONDT). Controlled Clinical Trials, 24:294-305, 2003.

The Ischemic Optic Neuropathy Decompression Trial Study Group, Development and validation of a

computerized expert system for evaluation of automated visual fields from the Ischemic Optic Neuropathy

Decompression Trial (IONDT). BMC Ophthalmology, 6:34, 2006.

The Ischemic Optic Neuropathy Decompression Trial Study Group, Visual fields at follow-up in the

Ischemic Optic Neuropathy Decompression Trial (IONDT). Ophthalmology, 115:1809-1817, 2008.

49

ABSTRACTS:

Horton, J.C. and Hedley-Whyte, E.T., Protein movement across the blood-brain barrier in hypervolemia, J.

Neuropath. Exp. Neurol., 37:630, 1978.

Horton, J.C. and Hubel, D.H., Correlation of cytochrome oxidase staining with 2-deoxyglucose uptake in

monkey visual cortex, Arch. Biol. Med. Exp., 13:12, 1980.

Horton, J.C. and Hubel, D.H., Cytochrome oxidase stain preferentially labels intersection of ocular

dominance and vertical orientation columns in macaque striate cortex, Soc. Neurosci., 6:113.5, 1980.

Horton, J.C., Effect of blocking retinal on-channels with aminophosphonobutyric acid (APB) on the cat

visual system, Soc. Neurosci., 7:24, 1981.

Horton, J.C., Dagi, L.R., McCrane, E.P., de Monasterio, F.M., Reconstruction of eye-dominance column

pattern in human visual cortex, Invest. Ophthalmol. Vis. Sci. Suppl. 29:116, 1988.

Rando, T.A., Horton, J.C., and Layzer, R.B., Wolfram's syndrome: MRI evidence of cerebellar and brainstem

atrophy, Neurology, 41:242, 1991.

Stryker, M.P. and Horton, J.C., Labeling of ocular dominance columns in amblyopic macaque monkey using

cytochrome oxidase histochemistry, Soc. Neurosci., 611.10, 1992.

Horton, J.C. and Stryker, M.P., Anisometropia induces amblyopia without shrinkage of ocular dominance

columns in human striate cortex, Soc. Neurosci., 611.11, 1992.

Horton, J.C., The anatomical basis of amblyopia in primate visual cortex, Neuro-Ophthalmol. Japan, 10:27,

1992.

Horton, J.C., The representation of the blind spot in human striate cortex, J. Japan Glaucoma Soc., 2:28-29,

1992.

Horton, J.C., Attenuation of the ipsilateral eye's dominance columns between 20o-60

o in human striate cortex

correlates with the steeper nasal slope of the hill of vision, Proc. Xth

International Perimetric Soc., Kyoto,

Japan, 1992.

Drake, M., Seiff, S.R., Horton, J.C., Bilateral visual field improvement following optic nerve sheath

fenestration in pseudotumor cerebri, Proc. Xth

International Perimetric Soc., Kyoto, Japan, 1992.

Horton, J.C. and Stryker, M.P., Ocular dominance columns within the foveal representation of macaque

striate cortex are less susceptible to shrinkage induced by early monocular deprivation, Soc. Neurosci.,

19:370.19, 1993.

Horton, J.C., Effect of early monocular enucleation upon cytochrome oxidase activity in monkey and human

visual cortex, Soc. Neurosci., 24:98.14, 1994.

50

Horton, J.C. and Hocking, D.R., Newborn monkeys have well-segregated ocular dominance columns

organized in an adult-like mosaic prior to visual experience, Soc. Neurosci., 25:509.1, 1995.

Carter, S.R., Seiff, S.R., Horton, J.C., Optic nerve decompression for visual loss in AIDS patients with

cryptococcal meningitis, ARVO, 1996.

Hocking, D.R., Horton, J.C., Pronounced intrinsic variability of ocular dominance column periodicity in

normal macaque monkeys, Soc. Neurosci., 26:682.9, 1996.

Horton, J.C. and Hocking, D.R., Anatomical demonstration of ocular dominance columns in striate cortex of

the squirrel monkey, Soc. Neurosci., 26:114.11, 1996.

Horton, J.C. and Hocking, D.R., Relative magnification of the central visual field representation in striate

cortex of macaques and humans, Soc. Neurosci., 27:755.11, 1997.

Hocking, D.R. and Horton, J.C., Contrasting effects of eyelid suture and retinal laser lesions upon

cytochrome oxidase activity in layer IVc of macaque striate cortex, Soc. Neurosci., 27:801.4, 1997.

Horton, J.C. and Hocking, D.R., Experimental strabismus reduces metabolic activity in ocular dominance

columns serving the deviated eye. Soc. Neurosci., 28:105.5, 1998.

Hocking, D.R. and Horton, J.C., Complete flat-mounting of the macaque cerebral cortex reveals a new

cytochrome oxidase pattern in extrastriate visual cortex. Soc. Neurosci., 28:834.9, 1998.

Horton, J.C., Hocking, D.R., and Adams, D.L., Comparison of ocular dominance columns in normal and

strabismic squirrel monkeys. Soc. Neurosci., 29:721.10, 1999.

Adams, D.L., Hocking, D.R., and Horton, J.C., Representation of the Purkyně retinal tree in primate striate

cortex. Soc. Neurosci., 29:531.4, 1999.

Hocking, D.R., Adams, D.L., and Horton, J.C., A new method for rapid visualization of ocular dominance

columns in macaque striate cortex. Soc. Neurosci., 29:572.15, 1999.

Sincich, L.C. and Horton, J.C., A reappraisal of the projection pattern from macaque striate cortex to the

pale, thin, and thick cytochrome oxidase Stripes in V2. Soc. Neurosci., 31:11.2, 2001.

Horton, J.C. and Sincich, L.C., Pale cytochrome oxidase V2 stripes receive the richest projection from

macaque striate cortex. Soc. Neurosci., 31:11.3, 2001.

Adams, D. L. and Horton, J.C., A precise retinotopic map of the primate striate cortex generated from

angioscotomas. Soc. Neurosci., 31:619.45, 2001.

Adams, D. L. and Horton, J.C., Shadows from retinal blood vessels cause local amblyopia by deprivation of

photoreceptors. Vision Sciences Society, 2002.

Horton, J. C. and. Sincich, L. C., A decussation error in the optic chiasm revealed by an anomalous pattern of

ocular dominance columns in macaque striate cortex. Soc. Neurosci., 32:325.4, 2002.

51

Sincich, L. C. and Horton, J. C., Double-labeling of the projections from striate cortex to extrastriate areas

V2 and MT in the macaque monkey. Soc. Neurosci., 32:325.3, 2002.

Adams, D. L. and Horton, J.C., Size and density of retinal blood vessel shadows required to induce re-

modeling of geniculate afferents in monkey visual cortex. Soc. Neurosci., 32:325.5, 2002.

Adams, D. L. and Horton, J.C, Cortical columns without a function. Journal of Vision, 3(9):108, 2003.

Sincich, L.C. and Horton, J. C., A koniocellular-dominated projection from the lateral geniculate nucleus to

macaque visual area MT. Soc. Neurosci., 33:125.8, 2003.

Adams, D. L. and Horton, J. C., Proportionate scaling of visual cortical areas revealed in complete

flatmounts of macaque cerebral cortex. Soc. Neurosci., 33:818.11, 2003.

Horton, J.C., Park K.V., Wohlgemuth, M.J., Sincich, L.C., A direct projection from the lateral geniculate

nucleus to area MT: implications for blindsight. Neuro-Ophthalmology 28:24, 2004.

Sincich, L.C., Park K.V., Adams, D.L., Economides J.R., Horton J.C. Temporal reliability of primate lateral

geniculate neurons to the luminance dynamics of natural scenes. Soc. Neurosci., 34:598.2, 2004.

Horton, J.C., Sincich, L.C., How specific is V1 input to V2 thin stripes? Soc. Neurosci., 34:18.1, 2004.

Economides J.R., Horton, J.C., An in vitro method for revealing cytochrome oxidase patches in intact striate

cortical flatmounts. Soc. Neurosci., 34:646.4, 2004.

Adams, D.L., Horton, J.C., Ocular preference of cells in layer 4c of the squirrel monkey. Soc. Neurosci.,

34:18.3, 2004.

Sincich, L.C., Park, K.F., Adams, D.L., Economides J.R., Horton, J.C., Coordinated burst firing in the retina

and lateral geniculate nucleus of the macaque. Soc. Neurosci., 35:506.20, 2005.

Jocson, C.M., Sincich, L.C., Horton, J.C., A layer 4B projection from V1 patches to V2 thin stripes. Soc.

Neurosci., 35:854.13, 2005.

Economides, J.R., Park K.F., Adams, D.L., Horton, J.C, Ocular motor behavior in macaques with surgical

strabismus. Soc. Neurosci., 35:745.17, 2005.

Vagefi, M.R., Larson, D.A., Horton J.C., Radiation Treatment of Optic Nerve Sheath Meningioma: Visual

Improvement Can Begin Before Radiotherapy Ends. ARVO 2006, 762/B683.

Jocson, C.M., Sincich, L.C., Horton, J.C., Projections from V1 to V2 in amblyopia. Soc. Neurosci., 36:437.4,

2006.

Economides, J.R., Adams, D.L., Horton, J.C., Perceptual suppression revealed by dichoptic visual field

mapping in strabismus. Soc. Neurosci., 36, 801.18, 2006.

Adams, D.L., Horton, J.C., Ocular dominance columns in strabismus. Soc. Neurosci., 36:545.25, 2006.

52

Sincich, L.C., Sharpee, T.O., Horton, J.C., Temporal filter transformation across the macaque

retinogeniculate synapse. Soc. Neurosci., 36:240.15, 2006.

Carandini, M., Horton, J.C., Sincich, L.C., Postsynaptic mechanisms converting retinal spike trains into

geniculate spike trains. Soc. Neurosci., 36:11.14, 2006.

Jocson, C.M., Sincich, L.C., Horton, J.C., Quantitative comparison of the V1 interpatch projections to pale

and thick stripes in V2. Soc. Neurosci., 37:280.21, 2007.

Horton, J.C., Sincich, L.C., Sharpee, T.O., Spike trains as stimulus features in the macaque lateral geniculate

nucleus. Soc. Neurosci., 37: 392.19, 2007.

Adams, D.L., Sincich, L.C., Horton, J.C., The complete pattern of ocular dominance columns in human

striate cortex. Soc. Neurosci., 37:393.8, 2007.

Sincich, L.C., Zhang, Y., Tiruveedhula, P., Adams, D.L., Yang, Q., Vogel, C.R., Arathorn, D.W., Horton,

J.C., Roorda, A., Mapping LGN receptive fields by single cone stimulation with adaptive optics scanning

laser ophthalmoscopy. Soc. Neurosci., 37: 228.5, 2007.

Sincich, L.C., Sharpee, T.O., Horton, J.C., Chromatic spatiotemporal receptive field mapping with 3-

dimensional 1/frequency noise. Soc. Neurosci., 38: 366.25, 2008.

Adams, D.L., Economides, J.R., Horton, J.C., Single unit responses in striate cortex of awake macaques with

strabismus. Soc. Neurosci., 38: 462.19, 2008.

Adams, D.L., Economides, J.R., Jocson, C.M., Horton, J.C., Implantation and care of recording chambers for

neurophysiological experiments in alert monkeys: a survey of current methods and a new chamber design.

Soc. Neurosci., 39: 166.17, 2009.

Sincich, L.C., Economides, J.R., Horton, J.C., Sharpee, T.O. Comparing the chromatic spatiotemporal

receptive fields of connected retinal ganglion cells and LGN neurons in the macaque. Soc. Neurosci., 39:

848.14, 2009.

Gutilla, E.A., Sharpee, T.O., Horton, J.C., Sincich, L.C. Diversity of interspike interval distributions in

macaque retinal ganglion cells and thalamic relay neurons. Soc. Neurosci., 40:276.12, 2010.

Economides, J.R., Sincich, L.C., Adams, D.L., Horton, J.C. Orientation tuning of cells in cytochrome

oxidase patches of macaque striate cortex examined with 100-microelectrode arrays. Soc. Neurosci.,

40:483.15, 2010.

Economides, J.R., Adams, D.L., Horton, J.C., Sincich, L.C., Variability of orientation tuning for neurons in

cytochrome oxidase patches versus interpatches of macaque V1. Soc. Neurosci., 41:428.06, 2011.

Adams, D.L., Economides, J.R., Sincich, L.C., Horton, J.C., Cortical metabolic activity matches the pattern

of visual suppression in strabismus. Soc. Neurosci., 42:623.14, 2012.

53

Desai, S., Lawton M., McDermott, M., Horton, J.C., Vertical gaze restriction and ptosis after neurosurgical

removal of the orbital roof. ARVO, 2014.

Economides, J.R., Adams, D.L., Horton, J.C., How do patients with strabismus locate visual targets? Soc.

Neurosci., 44:237.03, 2014.

Adams, D.L., Economides, J.R., Horton, J.C., Stability of eye position in strabismus. Soc. Neurosci.,

44:333.01, 2014.

Horton, J.C., Economides, J.R., Adams, D.L., Vascular supply of the cerebral cortex is specialized for cell

layers but not columns. Soc. Neurosci., 44:772.08, 2014.

Economides, J.R., Adams, D.L., Horton, J.C., Normal correspondence of tectal maps for saccadic eye

movements in strabismus. Soc. Neurosci., 46:715.24, 2016.

Adams, D.L., Economides, J.R., Horton, J.C., Cortical representation of a myopic peripapillary crescent:

evidence against fill-in of retinal lesions. Soc. Neurosci., 46:434.06, 2016.

Horton, J.C., Economides, J.R., Adams, D.L., Eye movement recordings of spontaneous fusion loss in

intermittent exotropia. Soc. Neurosci., 46:715.15, 2016.

RESEARCH IN PROGRESS:

My clinical practice is focused on pediatric ophthalmology and neuro-ophthalmology. Through clinical

research, my goal is to find better methods to diagnose and treat the diseases which affect my patients.

Often, my laboratory research is inspired and guided by the patients that I encounter with visual problems in

my office.

In the laboratory, I am studying the organization and function of the central visual system in primates.

I am presently the principal investigator of a study entitled "Structural Basis of Amblyopia and Strabismus" supported by the National Eye Institute. My ultimate goal is to explain how visual perception occurs in the human brain. To pursue this objective, we conduct experiments in normal, amblyopic, and strabismic primates. Research on amblyopic and strabismic subjects is important, for two reasons. First, amblyopia causes visual impairment in about 2% of the American population. Strabismus is even more common, and often leads to amblyopia and loss of stereovision. Research upon these diseases therefore has important practical implications for the prevention of visual loss and the protection of public health. Second, research on amblyopia and strabismus can provide insight into the normal function of the visual system. In strabismus and amblyopia, visual function becomes impaired early in life, yet the visual pathway suffers no destructive physical lesion. If one can determine exactly which cells and connections have been disrupted by abnormal sensory experience in subjects with amblyopia or strabismus, one will presumably have discovered properties and pathways vital for normal perception.

The purpose of the human visual system is to provide a supremely efficient means for the rapid

assimilation of information from the environment to guide behavior. The retina serves as a peripheral

transducer, by converting images of light into patterns of electrical signals. These signals are conducted

along the primary optic pathway to a relay nucleus in the thalamus, called the lateral geniculate body. We are

54

seeking to learn what factors govern the transmission of retinal spikes across the geniculate synapse, so that

they are transmitted to the primary visual cortex. Within the primary visual cortex, visual information is

processed by cells arranged within an elaborate system comprised of overlapping vertical columns and

horizontal layers. Another major objective is to map the functional architecture of the primary visual cortex,

to understand how groups of cells are organized in a modular fashion for information analysis. We are using

autoradiography, axon tracing, cytochrome oxidase histochemistry, functional gene expression, and

electrophysiology to accomplish this aim.

After initial processing by the primary visual cortex, images are transferred to several dozen extrastriate

visual areas, where perception takes place. It is unclear why the primate brain has so many different visual

areas beyond the primary visual cortex. One theory suggests that various cortical areas are specialized for

processing different aspects of vision, e.g., motion, color, form, etc. We are engaged in mapping the

boundaries, layout, topography, and modular architecture of visual regions in extrastriate cortex, to determine

how they contribute to visual perception. At present, our attention is focussed upon areas V2, V3, VP, V3A,

V4, and V5, which are situated close to V1.

Amblyopia is a disease of the cortex caused by visual deprivation. The most severe form occurs in a

child who grows up with a dense unilateral cataract. Even after removal of the cataract, vision remains poor

because of projections serving the amblyopic eye within the brain are miswired. Our research is seeking to

delineate the critical periods for normal development and plasticity of the visual cortex, and to understand

how the circuitry and function of the visual cortex are disrupted by visual deprivation and strabismus. We

have developed a macaque model of strabismus, and are conducting experiments in awake, behaving animals

to uncover the neural mechanisms responsible for visual suppression.

We use the macaque for most of our research, because it provides an excellent model for visual

processing in the human brain. In addition, whenever possible, we conduct parallel studies in human subjects.

For example, we have mapped the ocular dominance columns in the human primary visual cortex. We have

also mapped patterns of visual suppression in many patients with strabismus. By extending and confirming

many of our findings in humans, we have confidence that our animal experiments are yielding valid insights

into the development and function of the human visual cortex.

updated: april 2018 curriculum vitaevision.ucsf.edu/hortonlab//cv/horton_cv.pdf1 updated: april 2018...

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