Michel SainvilleMarketing Division

Background informations

Advances in endoscopic

technology

Longer procedures,

deeper sedationHigher ARF risk

ARF Statistics

Every day, in each european country, the 0,01% of the population undergoes an UE.

The 5% of those patients develops an ARF.

(P/10k)(0.07 ± ε)Time

Europe= (731mln/10k)(0.07 ± 0.02)1

3˙655 to 6˙579 ARF per day.

Italy= (61mln/10k)(0.07 ± 0.02)1 305 to 549 ARF per day

Physician’s dilemmaTreating ARF

Non invasive ventilation

Planned

Prediction errors

Unexpected

Procedure interruption

Intubation

RisksCosts

Immediate and unplanned intra-procedural ventilation

Physician’s dilemmaTreating ARF

Non invasive ventilation

Planned

Prediction errors

Unexpected

Procedure interruption

immediate ventilation

Intubation

RisksCosts

Applications

•Tracheal intubationEmergency department

•FOB: fiberoptic bronchoscopy

•Gastroscopy•Enteroscopy•TEE: trans-esophageal echocardiography

•EBUS: endobronchial ultrasound

•ERCP: Endoscopic retrograde cholangiopancreatography

Endoscopicprocedures

MARKET SIZE

Assumptions

• Fewest ARF scenario

• Even treatment proportions

• Intra-procedural ventilation only (- NIV, CPAP)

EU market size 219˙300 units per year

Italian estimated market size 18˙300 units per year

Thank You