unlocking the potential for next generation digestive...

41
Unlocking the potential for next generation digestive health products: ensuring knowledge transfer and funding opportunity between academia and industry Simone Maccaferri

Upload: others

Post on 14-Mar-2020

3 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Unlocking the potential for next generation

digestive health products:

ensuring knowledge transfer and funding

opportunity between academia and industry

Simone Maccaferri

Page 2: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How we work now

Page 3: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Facts and figures

Page 4: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

FAT

TYPE OF INGESTED

FERMENTABLE

CARBOHYDRATES

MICROBIOTA MAKE-

UP

PROTEINS

CARBOHYDRATES

THE MOST REMARKABLE EXAMPLE OF MICROBIOTA PLASTICITY IS ITS CAPACITY TO RAPIDLY RESPOND TO DIETARY CHANGES

Why Gut Microbiota?

Page 5: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Why Gut Microbiota?

Candela et al., Trends Microbiol 2012

Maccaferri et al., Dig Dis 2012

Page 6: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Facts and figures

Page 7: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

And so, what?

Page 8: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

But…

Page 9: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How?

Page 10: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

So… we must bridge

the gap!

Page 11: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Linking 3 domains

can make the difference

Page 12: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

» Understanding the needs:

it is of striking importance to understand the

technological and research needs of the industry to design a

tailored knowledge transfer strategy

» Understanding the potential:

every industry has a potential to be developed. What

makes the difference is the ability of exploiting your

knowledge base to drive that potential to become reality

through the appropriate strategy.

Page 13: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

First...

Page 14: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Gut microbiota has an age-related trajectory

How? /market niches

Page 15: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How? /trending ingredients

» Wholegrain, fibers and vitamin D

are top ingredients that two

thirds of consumers trying to

manage their weight added to

their diet last year

» One third added more iron, oat

bran or flaxseed oil

» One quarter added natural

sweeteners, probiotics and soy

protein

Page 16: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How? /market trends

Page 17: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How? /market trends

Page 18: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

2015 trends for food industry (FoodNavigator)

How? /market trends

Page 19: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How? /expanding markets

Page 20: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Second...

Page 21: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How? /the researchers

Page 22: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How? /the researchers

Integration

Innovation

Multidisciplinarity

Page 23: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How? /the researchers

» Focusing on win-win situations:

– Increased networking

– Source for new ideas: the research needs of industry are

often interconnected with the research interests of

universities new perspectives on applied and basic research

– Economic valuation through appropriate product and process

enhancement

–Design and delivery of programmes that are relevant to

current and future business needs

Page 24: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

» Identifying concrete deliverables for the business:

– Establishment of long-term relationships and profitable partnerships

to tackle a wide spectrum of ideas, topics, and problems

– Cost-effective solutions to research needs

– Generation of innovation: technical problem solving, process

improvement, new product development, and breakthrough ideas

– Preparation of a highly skilled workforce for future placement

opportunities

Page 25: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

How? /a model

Page 26: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

But...

Page 27: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

But...

Regulation (EC) no 1924/2006 on claims made on foods

Nutritional and health claims are only be authorized for

use in the EU after a scientific assessment of the

evidence supporting the claim.

Page 28: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

But...

Nutrition and health claims shall:

• Be substantiated by generally accepted scientific evidence

• Refer to a beneficial nutritional/physiological effect

• Be understandable for the average consumers

• Be accompanied by nutrition information

• Refer to the food ready for consumption

• The nutrient/substance on which the claim is made shall be present

in the product in a quantity to produce the effect.

• Reasonable consumption of the product shall provide a quantity of

the nutrient/substance to produce the effect

Page 29: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

A balanced solution

Page 30: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

» Understanding how to support/fund industry-driven

applied research:

Solid knowledge of

national and EU

funding/partnering

opportunities

Full understanding of

the specificities of the

industry

Page 31: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

The complex funding scenario

Page 32: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

But...

Page 33: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

But...

Page 34: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

http://www.nu-age.eu/

NuAge

NuAge strategy embraces a wide EU population over 65

years from different countries (NEWS) who will undergo

detailed characterisation at functional and molecular

level. Dietary intervention will be utilised for elderly

tailored- foods

Page 35: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

http://www.mynewgut.eu

MyNewGut

Page 36: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation
Page 37: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation
Page 38: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

An example /product

Page 39: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

An example /product

Industry-funded PhD

for Collaborative

Research

Clinical trial with own

industrial funding

Product enhancement

with SME competitive

award

Page 40: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Another example /skills

Bio statistics and power analysis

for human studies in food

industries

Page 41: Unlocking the potential for next generation digestive ...d3hip0cp28w2tg.cloudfront.net/uploads/block_files/2014-12/dr-simone-maccaferri-1.pdfUnlocking the potential for next generation

Simone Maccaferri

Agro-Food, Bioeconomy, Energy and Environment

Unit

European Research and Innovation Office

e-mail: [email protected]

Tel.:+39 051 2088469 - Mob:+ 39 320 4788775

Which activities do you want

to do together ?