University of Groningen

Improving clinical management in ANCA-associated vasculitisde Joode, Anoek Afra Elisabeth

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite fromit. Please check the document version below.

Document VersionPublisher's PDF, also known as Version of record

Publication date:2016

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):de Joode, A. A. E. (2016). Improving clinical management in ANCA-associated vasculitis. RijksuniversiteitGroningen.

CopyrightOther than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of theauthor(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons).

Take-down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.

Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons thenumber of authors shown on this cover page is limited to 10 maximum.

Download date: 27-03-2021

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Maintenance therapy in ANCA-associated

vasculitis: who needs what and for how long?

Nephrol Dial Transplant 2015; 30: i150-i158.

6

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

88

Chapter 6

ABSTRACT

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

INTRODUCTION

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Relapses- prediction of risk

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

Relapses- consequences

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Relapses- impact on quality of life (QOL)

Relapses- prevention

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Table 1

Inclusion Induction Maintenance

CYCAZEREM

WGET

WEGENT

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

Duration Relapse AE’s

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Inclusion Induction Maintenance

IMPROVE

Table 1

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

Duration Relapse AE’s

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Relapses- duration of maintenance therapy

Figure 1

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

Relapses- new developments

(Clinical trials.gov. NCTO1663623)

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Table 2

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

RECOMMENDATIONS

Maintenance therapy: what to choose?

Table 2

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

In case of relapse

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

REFERENCES

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Longterm maintenance therapy: review

6

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Chapter 6

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode

Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016Processed on: 4-8-2016

504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode504574-L-bw-deJoode