university children’s hospital tübingen department...
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th6 International Tübingen-Symposium
on Pediatric Solid Tumorsth thJune 10 -11 , 2016
Tübingen, Germany
University Children’s Hospital TübingenDepartment of Pediatric Surgery and Urology
Department of Pediatric Hematology/Oncology
New Treatment Concepts in Pediatric Renal Tumors 0
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Scientific program
Wednesday, 8th June 2016
Thursday, 9th June 2016
Friday, 10th June 2016
09.00 – 18.00 SIOP Renal Tumor Study Group (RTSG) Annual Meeting(closed)
SIOP Renal Tumor Study Group (RTSG) Annual Meeting(closed)
08.00 – 08.15 Welcome address and Congress opening (J. Fuchs, N. Graf)
08.15 – 10.00 Session I: Clinical Trials, PathologyChairs: J. Fuchs, R. Shamberger
08.15 – 08.30 Update on the upcoming umbrella protocol for pediatric renaltumorsN. Graf, Homburg
08.30 – 08.45 Results of the ARENO321 trial including anaplastic Wilms TumorsJ. Geller, Cincinnati
08.45 – 09.00 Treatment of very low risk Wilms Tumors – results of the ARENO532 trialE. Mullen, Boston
09.00 – 09.15 Histological changes in Wilms Tumors following chemotherapy. Experiences and outlook to the upcoming umbrella protocolG. Vujanic, Cardiff
09.15 – 09.30 Pathological staging of Wilms Tumors in the renal hilus I. Leuschner, Kiel
09.30 – 09.45 Сongenital mesoblastic nephroma: single center experience in RussiaD. Kachanov (Moscow), N. Merkulov, A. Mitrofanova, A. Kazakova,A. Chililova, S. Talypov, M. Teleshova, G. Tereschenko, E. Feoktistova,T. Shamanskaya, S. Varfolomeeva
09.45 – 10.00 Outcome of Wilms' Tumor in Children: A 10-year Multi-Center Experience from Saudi Arabia- Preliminary Analysis under the umbrella of the Saudi Arabian Pediatric Hematology Oncology Society (SAPHOS)I. Abosoudah (Jeddah), I. Al Fawaz, M. Viqaruddin, M. Al Qaissi,D. Bushnak, N. Alkhayat, A. Ali
10.00 – 10.30 Coffee Break
08.30 - 16.00
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10.30 – 12.30 Session II: Clinical researchChairs: J. Geller, M. van den Heuvel Eijbrink
10.30 – 10.45 Intensity-Modulated Radiotherapy (IMRT) for pediatric renal tumorsC. Rübe, Homburg
10.45 – 11.00 Treatment results of nephroblastomatosisR. Furtwängler, Homburg
11.00 – 11.15 Liver metastases from nephroblastomaP. Ehrlich, Ann Arbor
11.15 – 11.30 Non-Wilms Renal tumorsM. van den Heuvel Eijbrink, Utrecht
11.30 – 11.45 Treatment strategies for pediatric renal cell carcinomaB. Selle, Berlin
11.45 – 12.00 Outcome of relapsed Wilms Tumors: a single center experienceA. Schiavetti (Rome), V. Pedetti, D. Cozzi, C. Celani, O. Marrucci,F. Pellicori, G. Varrasso
12.00 – 12.10 Renal cell carcinoma in children: report of two casesN. Uskova (Moscow), N. Merkulov, S. Talypov, O. Raisa, D. Kachanov,A. Mitrofanova, S. Varfolomeeva, T. Shamanskaya, N. Grachev
12.10 – 12.30 Discussion
12.30 – 13.30 Lunch
13.30 – 15.30 Session III: Surgery 1Chairs: N. Graf, E. Mullen
13.30 – 13.50 Surgery for vena cava thrombosis in nephroblastomaR. Shamberger, Boston
13.50 – 14.05 A new classification for nephron-sparing surgery (NSS) in Wilms TumorsG. Audry, Paris
14.05 – 14.20 NSS for unilateral Wilms Tumors – technical aspectsJ. Godzinski, Wroclaw
14.20 – 14.35 Long term follow-up of renal function after NSS for unilateral and bilateral nephroblastomaD. Cozzi, Rome
14.35 – 14.50 Results of treatment of children with bilateral nephroblastomaМ.А. Rubansky (Moscow), А.P. Kazantsev, P.A. Kerimov,M.V. Rubanskaya, O.A. Kapkova, D.V. Rybakova, A.V. Hizhnikov
14.50 – 15.05 Nephron-sparing surgery for pediatric renal tumors with application of hydrojet dissection, thermoablation and haemostatic energy technologiesT. A. Sharoev (Moscow) and A.G. Prityko
15.05 – 15.30 Coffee Break
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15.30 – 17.00 Session IV: Chemotherapy and alternative strategies for Pediatric renal tumorsChairs: R. Handgretinger, P. Ehrlich
15.30 – 15.45 Novel agents and future COG high risk pediatric renal tumor trials J. Geller, Cincinnati
15.45 – 16.00 Wilms tumor relapses: “standard” of care and perspectivesF. Spreafico, Milan
16.00 – 16.15 Stage IV Favorable Histology nephroblastoma: the COG experienceE. Mullen, Boston
16.15 – 16.30 Incorporating new biological markers into risk stratification of Wilms TumorsK. Pritchard-Jones, London
16.30 – 16.45 Vincristine, Irinotecan and Bevacizumab in relapsed anaplastic Wilms TumorsA. Schiavetti (Rome), G. Varrasso, P. Collini, E. Ferrara, M. Paiano,A. Clerico
16.45 – 17.00 Haploidentical stem cell transplantation and subsequent immunotherapy with antiGD2 antibody for patients with relapsed metastatic neuroblastomaT. Flaadt (Tuebingen), P. Lang, M. Ebinger, P. Schlegel, H.M. Teltschik, C.P. Schwarze, T. Feuchtinger, J. Fuchs, S. Warmann, J Schäfer, R. Ladenstein, H. Lode, H. Loibner, W. Schwinger, C. Urban, R. Handgretinger
08.30 – 09.30 Session V: Biology and Basic ResearchChairs: K. Pritchard-Jones, F. Spreafico
08.30 – 08.45 Genetical Background of Wilms TumorsM. Gessler, Wuerzburg
08.45 – 08.52 Functional analysis of DROSHA and DGCR8 mutations in Wilms tumors(Poster presentation)R. Vardapour, Wuerzburg
08.52 – 09.00 Phenotyping of the DROSHA and SIX1 Wilms tumor mutations in the mouse (Poster presentation)P. Kruber (Wuerzburg), M. Gessler
09.00 – 09.07 Analysis of MYCN and MAX mutations in Wilms tumor formation(Poster presentation)O. Jimenez Martin, Wuerzburg
09.07 – 09.15 Spheroid cell cultures as an in vitro Wilms tumor model(Poster presentation)J. Wegert (Wuerzburg), S. Bausenwein, C. Otto, E. Geißinger, M. Gessler
09.15 – 09.25 Liquid biopsy in nephroblastoma patients using tumor epitope detection in macrophagesS. Warmann (Tuebingen), E. Schmid, J. Fuchs, R. Handgretinger
09.25 – 09.30 Renal carcinoma with translocation Xp11.2(Poster presentation)M. Guibelalde (Palma de Mallorca), P. Carrillo, C. Marhuenda, E. Amador, F. Algaba, J. Echeveste, J.A. Salinas
09.30 – 10.00 Coffee Break
Saturday, 11th June 2016
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10.00 – 12.00 Session VI: Diagnostics and Surgery IIChairs: M. Gessler, J. Godzinski
10.00 – 10.15 Imaging strategies in bilateral nephroblastomaJ. Schäfer, Tuebingen
10.15 – 10.35 Surgery for bilateral nephroblastoma – technical aspectsB. Shamberger, Boston
10.35 – 10.50 Minimally-invasive surgery for nephroblastomaJ. Fuchs, Tuebingen
10.50 – 11.05 Surgery for primary and secondary pulmonary metastases in nephroblastomaS. Warmann, Tuebingen
11.05 – 11.20 The role of surgery in unilateral and bilateral nephroblastomatosisD. von Schweinitz, Munich
11.20 – 11.35 Extirpation of a large nephroblastoma preserving two parts of renal parenchyma seperated by the tumor in a patient with a contralateral non-functioning kidney(Short presentation)K. Breuling (Munich), J. Berndt, C. Kabs, K. Beutel, M.-M. Steinborn,S. Hosie
11.35 – 11.45 Discussion
11.45 Closing remarks (R. Handgretinger)
12.00 – 13.00 Lunch
www.nephroblastoma2016.com0
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Dear Colleagues and friends,
Welcome to the 6th International Tuebingen Symposium on Pediatric Solid Tumors. The Topic of our upcoming event is “New Treatment Concepts in Pediatric Renal Tumors”. Again, physicians and scientists from all over the world will come together to discuss the most recent developments in this field.
Currently, the SIOP Renal Tumor Study Group (RTSG) in close cooperation with representatives from the North American Study Group, is in the process of establishing the next trial protocol for the treatment of renal tumors in children. The Annual Meeting of the SIOP RTSG Steering Committee will take place in Tuebingen directly before our Symposium. Consecutively, the leading international experts on pediatric renal tumors (Oncology, Surgery, Radiology, Pathology, Radio-Oncology, Biology) will be present at the 6th Tuebingen Symposium. Their contributions together will assure an outstanding scientific value of the Symposium, however, we emphatically encourage abstract submissions to share a great variety of experiences during the event.
Over the years the Tuebingen Symposium on Pediatric Solid Tumors has become recognized as a comprehensive and sustainable meeting, which not only prevails through its scientific standard based on an interdisciplinary approach, but which also emerges because of its character and the cordial atmosphere at the different social events.
Tuebingen in June is a magnificent city with a lot of charm and atmosphere. We would like to invite you to join us for the 6th International Tuebingen Symposium and we are looking forward to welcoming you soon in our city.
Jörg FuchsProfessor ofPediatric Surgery
Rupert HandgretingerProfessor ofPediatric Oncology 0
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Organisation
University Children’s HospitalDepartment of Pediatric Surgery and UrologyDepartment of Pediatric Hematology / Oncology
Hoppe-Seyler-Str. 3D-72076 TuebingenGermany
Local organizing committee
Prof. Dr. med. Jörg FuchsProf. Dr. med. Rupert HandgretingerProf. Dr. med. Steven Warmann PD Dr. med. Martin EbingerDr. med. Andreas Schmidt
Congress Registration & Organisation
INTERPLANCongress, Meeting & Event Management AG
Nadja Riesen-LagodaLandsberger Str. 155, Haus 1, 80687 München Tel: 089 - 54 82 34-794 / Fax: 089 - 54 82 34-42
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Congress venue:
Main auditorium,
Dpt of Psychiatry and Psychotherapy(Building 202)Calwerstr. 1472076 Tuebingen
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