unesco intangible cultural heritage of humanity: mediterranean … · 2015-11-17 · applied...
TRANSCRIPT
1 Department of Drug Science and Technology, School of Pharmacy, University of Torino, Via Pietro Giuria 9, 10125 Torino, Italy
2 Directorate General of Food Safety and Nutriti on, Ministry of Health , Via G. Ribotta, 5, 00144 Rome, Italy
Abstract:
Keywords:
INTRODUCTION
Capitulare de villis vel curtis imperii Caroli Magni
Hortus simplicium
Unesco Intangible Cultural Heritage of Humanity: Mediterranean diet and Ethnobotanic knowledge
Convention for Safeguarding Intangible Cultural Herit age
knowledge and practices concerning nature and the universe
ethnobiology traditional knowledge
Ethnobotany: History and Methods for a Quantitative Ethnobotany
Homo sapiens
etc.
Interpretation and meaning of plant secondary metabolism
Figure 1 Primary and secondary metabolism reactions
chlorophyll + CO2 + light
Carbohydrates
Pentose cycle
Shikimic Acid
Aromatic amino acids
Cinnamic acid
PHENYLPROPANOIDS
Phosphoenolpyruvic acid
Pyruvic acid
Acetil CoenzimaA
Tricarboxylic acidsAmino acids
ALKALOIDS
Malonyl -CoA
FLAVONOIDSPHENOLS
Mevalonic acid
TERPENOIDSCAROTENOIDSSTEROIDS
etc
etc.
etc
etc.
why can the secondary metabolites (plant chemicals) affect human life ?
etc.
etc.
The reverse pharmacology: a new approach on the basis of ethnobotanical data
Digitalis purpurea
An Account of the Foxglove and some of its Medical Uses
Galanthus
etc.
Functional aspect of conventional food: innovative interpretation
etc
etc
Figure 2 Comparison between Medical and Nutritional Pharmacology (from Migrating principles of pharmacogenomics (PGx) to nutrigenomics (NGx) to enable the practice of preemptive nutrition. [from Gillies & Krul (83)]
etc
de novo
CONCLUSIONS
Figure 3 The step-by-step scientific basis of ethnobotany
Traditional usage of food and health plants = Ethnobotany 1
Thousand of Phychemicals inside a single plant 2
Criteria for selecting plants for investigation: selection basedon traditional usage 3
Experimental approach by means of Reverse Pharmacology Method 4
In a Nutritional Pharmacological point of view, the classic plant-based foodcontains Phytochemicals, able to maintain the homeostasis in human subjects. The Phytochemicals exert their physiological effects on the basis ofxenohormetic phenomenon. 5
Summary of the steps demonstrating the scientific basis of the ethnobotany, directly linked with the xenohormesis, a biological phenomenon described ashomeostasis promoting factor.
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