ultrasensitive monitoring of geographic atrophy...
TRANSCRIPT
Ultrasensitive monitoring of geographic atrophy (GA) progression
K . Gocho, V. Sarda, S. Falah, J.-A. Sahel M. Benchaboune, M. Ullern, and M. Paques
Clinical Investigation Center 503, INSERM, Quinze-Vingts National Eye Hospital, Paris, France
rtx1 clinical case report: dry AMD
Geographic atrophy: 5 months follow up
Imagine Eyes rtx1 clinical case report: dry AMD
66 year old female patient with dry age related macular degeneration (AMD).
Adaptive optics (rtx1)
at T0
Geographic atrophy: 5 months follow up
Imagine Eyes rtx1 clinical case report: dry AMD
66 year old female patient with dry AMD.
Adaptive optics (rtx1)
at T0 + 2 weeks
Geographic atrophy: 5 months follow up
Imagine Eyes rtx1 clinical case report: dry AMD
66 year old female patient with dry AMD.
Adaptive optics (rtx1)
at T0 + 1 month
Geographic atrophy: 5 months follow up
Imagine Eyes rtx1 clinical case report: dry AMD
66 year old female patient with dry AMD.
Adaptive optics (rtx1)
at T0 + 3 months
Geographic atrophy: 5 months follow up
Adaptive optics (rtx1)
at T0 + 5 months
Imagine Eyes rtx1 clinical case report: dry AMD
66 year old female patient with dry AMD.
Geographic atrophy: 5 months follow up
AO with border
positions
Imagine Eyes rtx1 clinical case report: dry AMD
Successive border positions at each visit.
Geographic atrophy: 5 months follow up
Successive border positions at each visit.
AO close-up of border positions
2W: +7 µm
T0 1M: +25 µm
3M: +12 µm
5M: +15 µm
Imagine Eyes rtx1 clinical case report: dry AMD
Conclusion
• Adaptive optics allows to detect the progression of atrophic lesions in as small time scale as a couple of weeks.
• Such small changes are not visible with conventional imaging techniques
• See also:
• K. Gocho, V. Sarda, S. Falah, J.-A. Sahel, M. Benchaboune, M. Ullern, and M. Paques, "Adaptive optics imaging of geographic atrophy," Investigative Ophthalmology & Visual Science, Vol.54. May 2013.
Imagine Eyes rtx1 clinical case report: dry AMD
