twiv 216: processing viral rna - microbe€¦ · synthesis of 5' cap capping enzyme . table...

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TWiV 216: Processing viral RNA Virology 101

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Page 1: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

TWiV 216: Processing viral RNA

Virology 101

Page 2: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

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Page 3: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

m7GpppG

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Page 4: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

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Page 5: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

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Page 6: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

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Page 7: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

mRNA splicing discovered in adenovirus infected cells

Page 8: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

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Page 9: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Splicing of pre-mRNA

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Page 10: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

RNA-RNA interactions during splicing

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Page 11: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

RNA catalysis without protein

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Page 12: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Alternative splicing

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Page 13: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Alternative polyadenylation and splicing

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Page 14: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Control of RNA processing during retrovirus infection

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Page 15: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Alternative polyadenylation and splicing during adenovirus infection

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Page 16: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Viral proteins can regulate alternative splicing

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Page 17: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

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Page 18: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Rev protein regulates export of HIV mRNAs

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Page 19: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Mechanism of Rev protein mediated RNA export

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Page 20: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Retroviral mRNA export without Rev protein

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Page 21: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

For temporal regulation of viral gene expression, or inhibition of the production of cell mRNAs

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Page 22: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Editing of viral mRNAs

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Page 23: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

RNA editing produces mRNA for Ebola virus glycoprotein

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Page 24: TWiV 216: Processing viral RNA - Microbe€¦ · Synthesis of 5' cap Capping enzyme . Table 10.1 Mechanisms of synthesis of 5'-terminal cap structures of viral mRNAs Mechanism Synthesis

Editing of hepatitis delta satellite virus RNA

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