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twins with klinefelter's syndrome

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1424 TWINS WITH KLINEFELTER’S SYNDROME |>" XBD=374 XHG=193 YBD=412 YHG=375>SiR,―We " XBD=456 XHG=389 YBD=405 YHG=375>add " XBD=552 XHG=472 YBD=405 YHG=375>here " XBD=586 XHG=568 YBD=405 YHG=384>a " XBD=718 XHG=601 YBD=406 YHG=375>fourth " XBD=768 XHG=733 YBD=406 YHG=382>to " XBD=840 XHG=783 YBD=406 YHG=375>the " XBD=950 XHG=855 YBD=407 YHG=376>three " XBD=1054 XHG=965 YBD=413 YHG=375>pairs " XBD=1109 XHG=1069 YBD=406 YHG=375>of " XBD=1329 XHG=1120 YBD=406 YHG=375>concordant " XBD=383 XHG=146 YBD=459 YHG=421>monozygotic " XBD=525 XHG=426 YBD=451 YHG=421>twins " XBD=652 XHG=569 YBD=451 YHG=421>with " XBD=924 XHG=696 YBD=453 YHG=421>Klinefelter’s " XBD=1150 XHG=969 YBD=460 YHG=421>syndrome " XBD=1329 XHG=1194 YBD=459 YHG=421>already " XBD=330 XHG=145 YBD=506 YHG=467>reported. " XBD=330 XHG=319 YBD=484 YHG=467>1 " XBD=266 XHG=189 YBD=560 YHG=529>The " XBD=358 XHG=283 YBD=559 YHG=529>first " XBD=457 XHG=374 YBD=559 YHG=528>twin " XBD=542 XHG=475 YBD=560 YHG=538>was " XBD=731 XHG=561 YBD=561 YHG=529>delivered " XBD=794 XHG=749 YBD=568 YHG=530>by " XBD=924 XHG=810 YBD=560 YHG=536>vertex " XBD=1170 XHG=941 YBD=567 YHG=529>presentation " XBD=1328 XHG=1188 YBD=567 YHG=529>(weight " XBD=232 XHG=145 YBD=607 YHG=576>3200 " XBD=307 XHG=247 YBD=613 YHG=575>g.), " XBD=392 XHG=324 YBD=606 YHG=575>and " XBD=466 XHG=407 YBD=606 YHG=575>the " XBD=608 XHG=482 YBD=607 YHG=576>second " XBD=670 XHG=625 YBD=614 YHG=576>by " XBD=809 XHG=686 YBD=607 YHG=576>breech " XBD=1052 XHG=823 YBD=614 YHG=576>presentation " XBD=1150 XHG=1067 YBD=607 YHG=575>with " XBD=1327 XHG=1165 YBD=614 YHG=575>asphyxia " XBD=283 XHG=145 YBD=659 YHG=621>(weight " XBD=388 XHG=301 YBD=652 YHG=622>3040 " XBD=466 XHG=406 YBD=659 YHG=621>g.), " XBD=518 XHG=485 YBD=652 YHG=629>at " XBD=578 XHG=535 YBD=652 YHG=623>39 " XBD=716 XHG=596 YBD=653 YHG=622>weeks’ " XBD=908 XHG=734 YBD=660 YHG=622>gestation. " XBD=1096 XHG=944 YBD=660 YHG=621>Physical " XBD=1181 XHG=1114 YBD=652 YHG=621>and " XBD=1326 XHG=1199 YBD=652 YHG=622>mental " XBD=384 XHG=144 YBD=705 YHG=667>development " XBD=471 XHG=403 YBD=698 YHG=676>was " XBD=663 XHG=492 YBD=699 YHG=667>retarded: " XBD=742 XHG=684 YBD=698 YHG=668>the " XBD=833 XHG=760 YBD=698 YHG=667>first " XBD=934 XHG=852 YBD=698 YHG=667>twin " XBD=1020 XHG=953 YBD=698 YHG=668>had " XBD=1106 XHG=1040 YBD=699 YHG=674>two " XBD=1271 XHG=1127 YBD=698 YHG=668>seizures " XBD=1326 XHG=1292 YBD=698 YHG=674>at " XBD=204 XHG=143 YBD=751 YHG=722>age " XBD=240 XHG=219 YBD=743 YHG=714>2 " XBD=362 XHG=255 YBD=751 YHG=722>years. " XBD=455 XHG=409 YBD=743 YHG=713>At " XBD=532 XHG=472 YBD=751 YHG=723>age " XBD=591 XHG=551 YBD=744 YHG=715>16 " XBD=692 XHG=608 YBD=745 YHG=713>both " XBD=805 XHG=707 YBD=744 YHG=713>twins " XBD=889 XHG=821 YBD=744 YHG=713>had " XBD=998 XHG=905 YBD=744 YHG=713>these " XBD=1144 XHG=1015 YBD=744 YHG=713>clinical " XBD=1323 XHG=1161 YBD=744 YHG=713>features: " XBD=339 XHG=142 YBD=790 YHG=758>eunuchoid " XBD=479 XHG=369 YBD=796 YHG=759>build, " XBD=806 XHG=509 YBD=798 YHG=759>underdeveloped " XBD=1020 XHG=836 YBD=797 YHG=760>secondary " XBD=1106 XHG=1049 YBD=790 YHG=769>sex " XBD=1324 XHG=1136 YBD=791 YHG=759>character- " XBD=245 XHG=141 YBD=842 YHG=805>istics, " XBD=367 XHG=263 YBD=844 YHG=805>slight " XBD=655 XHG=383 YBD=844 YHG=807>gynascomastia, " XBD=718 XHG=672 YBD=837 YHG=816>no " XBD=838 XHG=734 YBD=845 YHG=805>pubic " XBD=890 XHG=851 YBD=836 YHG=816>or " XBD=1036 XHG=900 YBD=844 YHG=805>axillary " XBD=1131 XHG=1049 YBD=843 YHG=806>hair, " XBD=1213 XHG=1145 YBD=836 YHG=806>and " XBD=1324 XHG=1227 YBD=837 YHG=806>small " XBD=209 XHG=140 YBD=883 YHG=851>soft " XBD=335 XHG=222 YBD=884 YHG=859>testes. " XBD=424 XHG=365 YBD=890 YHG=860>i.Q. " XBD=511 XHG=443 YBD=884 YHG=862>was " XBD=571 XHG=529 YBD=883 YHG=854>46 " XBD=624 XHG=588 YBD=883 YHG=853>in " XBD=699 XHG=641 YBD=886 YHG=853>the " XBD=787 XHG=715 YBD=883 YHG=853>first " XBD=897 XHG=804 YBD=888 YHG=852>twin, " XBD=981 XHG=914 YBD=883 YHG=853>and " XBD=1040 XHG=998 YBD=883 YHG=853>43 " XBD=1093 XHG=1057 YBD=883 YHG=852>in " XBD=1167 XHG=1109 YBD=883 YHG=853>the " XBD=1321 XHG=1185 YBD=884 YHG=853>second. " XBD=230 XHG=139 YBD=930 YHG=898>Both " XBD=342 XHG=242 YBD=929 YHG=899>twins " XBD=424 XHG=356 YBD=929 YHG=898>had " XBD=569 XHG=442 YBD=930 YHG=898>double " XBD=850 XHG=586 YBD=930 YHG=898>sex-chromatin " XBD=980 XHG=864 YBD=929 YHG=898>bodies " XBD=1029 XHG=994 YBD=929 YHG=898>in " XBD=1164 XHG=1047 YBD=929 YHG=898>buccal " XBD=1323 XHG=1179 YBD=935 YHG=908>smears; " XBD=207 XHG=138 YBD=976 YHG=945>and " XBD=312 XHG=227 YBD=976 YHG=945>both " XBD=399 XHG=331 YBD=976 YHG=945>had " XBD=461 XHG=418 YBD=976 YHG=945>48 " XBD=746 XHG=482 YBD=980 YHG=945>chromosomes, " XBD=912 XHG=766 YBD=980 YHG=945>XXXY, " XBD=966 XHG=932 YBD=975 YHG=954>as " XBD=1131 XHG=986 YBD=976 YHG=944>follows: " XBD=467 XHG=135 YBD=1240 YHG=1201>Testicular-biopsy " XBD=676 XHG=503 YBD=1240 YHG=1201>specimen " XBD=848 XHG=712 YBD=1232 YHG=1201>showed " XBD=1105 XHG=884 YBD=1239 YHG=1200>pronounced " XBD=1320 XHG=1138 YBD=1239 YHG=1200>hyalinisa- " XBD=208 XHG=134 YBD=1279 YHG=1248>tion " XBD=265 XHG=225 YBD=1278 YHG=1248>of " XBD=517 XHG=280 YBD=1279 YHG=1247>seminiferous " XBD=672 XHG=536 YBD=1278 YHG=1247>tubules " XBD=726 XHG=691 YBD=1277 YHG=1247>in " XBD=828 XHG=745 YBD=1278 YHG=1247>both " XBD=1003 XHG=845 YBD=1285 YHG=1247>patients, " XBD=1088 XHG=1021 YBD=1278 YHG=1247>and " XBD=1164 XHG=1106 YBD=1278 YHG=1247>the " XBD=1321 XHG=1182 YBD=1285 YHG=1247>urinary " XBD=411 XHG=136 YBD=1333 YHG=1294>gonadotrophin " XBD=598 XHG=427 YBD=1325 YHG=1294>excretion " XBD=679 XHG=613 YBD=1324 YHG=1303>was " XBD=801 XHG=695 YBD=1324 YHG=1293>above " XBD=857 XHG=815 YBD=1324 YHG=1294>48 " XBD=991 XHG=873 YBD=1325 YHG=1303>mouse " XBD=1137 XHG=1005 YBD=1324 YHG=1293>uterine " XBD=1244 XHG=1152 YBD=1324 YHG=1293>units " XBD=1321 XHG=1259 YBD=1332 YHG=1303>per " XBD=177 XHG=134 YBD=1371 YHG=1341>24 " XBD=318 XHG=213 YBD=1372 YHG=1340>hours " XBD=390 XHG=355 YBD=1371 YHG=1340>in " XBD=513 XHG=427 YBD=1371 YHG=1340>both " XBD=658 XHG=548 YBD=1371 YHG=1340>twins. " XBD=799 XHG=705 YBD=1371 YHG=1339>ABO " XBD=904 XHG=837 YBD=1371 YHG=1340>and " XBD=1020 XHG=942 YBD=1370 YHG=1340>MN " XBD=1320 XHG=1057 YBD=1379 YHG=1340>blood-groups, " XBD=303 XHG=137 YBD=1418 YHG=1387>secretion " XBD=391 XHG=323 YBD=1417 YHG=1387>and " XBD=663 XHG=407 YBD=1418 YHG=1386>non-secretion " XBD=720 XHG=681 YBD=1417 YHG=1386>of " XBD=962 XHG=733 YBD=1425 YHG=1386>blood-group " XBD=1144 XHG=980 YBD=1424 YHG=1386>antigens, " XBD=1218 XHG=1163 YBD=1418 YHG=1396>ear " XBD=1320 XHG=1235 YBD=1423 YHG=1396>wax, " XBD=343 XHG=135 YBD=1471 YHG=1433>mid-digital " XBD=458 XHG=373 YBD=1470 YHG=1433>hair, " XBD=574 XHG=489 YBD=1464 YHG=1440>taste " XBD=721 XHG=604 YBD=1470 YHG=1432>ability " XBD=786 XHG=750 YBD=1464 YHG=1439>to " XBD=1220 XHG=815 YBD=1471 YHG=1433>phenylthiocarbamide, " XBD=1320 XHG=1252 YBD=1464 YHG=1433>and " XBD=369 XHG=135 YBD=1519 YHG=1480>finger-prints " XBD=479 XHG=391 YBD=1511 YHG=1490>were " XBD=609 XHG=500 YBD=1510 YHG=1479>tested " XBD=684 XHG=630 YBD=1510 YHG=1478>for " XBD=855 XHG=705 YBD=1518 YHG=1479>zygosity " XBD=1055 XHG=876 YBD=1518 YHG=1479>diagnosis. " XBD=1193 XHG=1115 YBD=1511 YHG=1480>The " XBD=1319 XHG=1214 YBD=1518 YHG=1480>prob- " XBD=252 XHG=136 YBD=1565 YHG=1526>ability " XBD=309 XHG=269 YBD=1558 YHG=1526>of " XBD=380 XHG=322 YBD=1557 YHG=1526>the " XBD=471 XHG=396 YBD=1565 YHG=1527>pair " XBD=591 XHG=489 YBD=1565 YHG=1526>being " XBD=845 XHG=608 YBD=1564 YHG=1526>monozygotic " XBD=927 XHG=861 YBD=1557 YHG=1537>was |>" XBD=1066 XHG=946 YBD=1558 YHG=1527>0-9896 " XBD=1265 XHG=1084 YBD=1565 YHG=1527>according " XBD=1319 XHG=1283 YBD=1557 YHG=1534>to " XBD=295 XHG=137 YBD=1611 YHG=1573>Inouye’s " XBD=500 XHG=332 YBD=1604 YHG=1572>method. 2 " XBD=835 XHG=572 YBD=1611 YHG=1573>Monozygosity " XBD=910 XHG=871 YBD=1604 YHG=1573>of " XBD=999 XHG=942 YBD=1604 YHG=1573>the " XBD=1107 XHG=1035 YBD=1612 YHG=1573>pair " XBD=1210 XHG=1143 YBD=1605 YHG=1584>was " XBD=1319 XHG=1248 YBD=1604 YHG=1574>also " XBD=340 XHG=137 YBD=1651 YHG=1619>established " XBD=401 XHG=356 YBD=1658 YHG=1620>by " XBD=576 XHG=417 YBD=1650 YHG=1619>different " XBD=953 XHG=592 YBD=1658 YHG=1619>similarity-diagnosis " XBD=1137 XHG=970 YBD=1651 YHG=1620>methods. " XBD=280 XHG=178 YBD=1701 YHG=1673>These " XBD=385 XHG=295 YBD=1701 YHG=1673>twins " XBD=462 XHG=400 YBD=1701 YHG=1672>will " XBD=517 XHG=478 YBD=1701 YHG=1673>be " XBD=677 XHG=532 YBD=1708 YHG=1673>reported " XBD=724 XHG=691 YBD=1701 YHG=1673>in " XBD=825 XHG=739 YBD=1702 YHG=1682>more " XBD=932 XHG=841 YBD=1702 YHG=1674>detail " XBD=1120 XHG=948 YBD=1702 YHG=1673>elsewhere. HISAO TAKAYASU. Department of Urology, KENJI KINOSHITA TAKAYUKI TSUBOI TETSURO KURIHARA. Department of Human Genetics and Criminology, Institute of Brain Research, University of Tokyo, Tokyo. MICROANGIOPATHIC HÆMOLYTIC ANÆMIA |>" XBD=340 XHG=179 YBD=2207 YHG=2170>SIR,-In " XBD=447 XHG=360 YBD=2201 YHG=2170>their " XBD=665 XHG=468 YBD=2208 YHG=2169>interesting " XBD=902 XHG=685 YBD=2208 YHG=2169>preliminary " XBD=1224 XHG=923 YBD=2206 YHG=2169>communication, " XBD=1310 XHG=1246 YBD=2200 YHG=2170>Dr. " XBD=339 XHG=132 YBD=2254 YHG=2216>Rubenberg " XBD=425 XHG=358 YBD=2247 YHG=2216>and " XBD=495 XHG=443 YBD=2247 YHG=2217>his " XBD=701 XHG=516 YBD=2254 YHG=2216>colleagues " XBD=825 XHG=722 YBD=2255 YHG=2216>(Nov. " XBD=900 XHG=847 YBD=2253 YHG=2217>25, " XBD=953 XHG=920 YBD=2255 YHG=2225>p. " XBD=1075 XHG=978 YBD=2254 YHG=2216>1121) " XBD=1211 XHG=1096 YBD=2254 YHG=2223>report " XBD=1310 XHG=1230 YBD=2254 YHG=2225>pro- " XBD=254 XHG=131 YBD=2302 YHG=2263>longed " XBD=462 XHG=271 YBD=2302 YHG=2263>hxmolysis " XBD=563 XHG=481 YBD=2294 YHG=2264>with " XBD=719 XHG=580 YBD=2294 YHG=2263>red-cell " XBD=997 XHG=737 YBD=2301 YHG=2263>fragmentation " XBD=1188 XHG=1014 YBD=2301 YHG=2262>following " XBD=1310 XHG=1205 YBD=2300 YHG=2262>injec- " XBD=203 XHG=130 YBD=2341 YHG=2309>tion " XBD=259 XHG=220 YBD=2341 YHG=2310>of " XBD=291 XHG=273 YBD=2340 YHG=2320>a " XBD=486 XHG=309 YBD=2348 YHG=2310>coagulant " XBD=646 XHG=504 YBD=2341 YHG=2309>fraction " XBD=704 XHG=664 YBD=2341 YHG=2310>of " XBD=774 XHG=717 YBD=2341 YHG=2310>the " XBD=915 XHG=792 YBD=2341 YHG=2319>venom " XBD=973 XHG=933 YBD=2340 YHG=2310>of " XBD=1044 XHG=986 YBD=2340 YHG=2309>the " XBD=1223 XHG=1062 YBD=2348 YHG=2310>Malayan " XBD=1309 XHG=1241 YBD=2347 YHG=2309>pit- " XBD=234 XHG=129 YBD=2395 YHG=2356>viper, " XBD=464 XHG=246 YBD=2395 YHG=2356>Agkistrodon " XBD=688 XHG=476 YBD=2393 YHG=2357>rhodostoma, " XBD=773 XHG=701 YBD=2388 YHG=2357>into " XBD=912 XHG=785 YBD=2387 YHG=2357>rabbits " XBD=960 XHG=925 YBD=2387 YHG=2356>in " XBD=1084 XHG=972 YBD=2387 YHG=2356>which " XBD=1154 XHG=1096 YBD=2387 YHG=2357>the " XBD=1308 XHG=1166 YBD=2387 YHG=2356>fibrino- " XBD=208 XHG=128 YBD=2441 YHG=2402>lytic " XBD=353 XHG=228 YBD=2441 YHG=2410>system " XBD=440 XHG=372 YBD=2435 YHG=2403>had " XBD=545 XHG=459 YBD=2434 YHG=2404>been " XBD=743 XHG=565 YBD=2434 YHG=2403>inhibited. " XBD=877 XHG=778 YBD=2441 YHG=2403>They " XBD=1031 XHG=896 YBD=2441 YHG=2410>suggest " XBD=1123 XHG=1050 YBD=2434 YHG=2403>that " XBD=1161 XHG=1143 YBD=2433 YHG=2413>a " XBD=1309 XHG=1182 YBD=2433 YHG=2403>similar " XBD=261 XHG=127 YBD=2488 YHG=2458>process " XBD=363 XHG=284 YBD=2488 YHG=2459>may " XBD=486 XHG=384 YBD=2480 YHG=2459>occur " XBD=542 XHG=507 YBD=2480 YHG=2449>in " XBD=692 XHG=563 YBD=2480 YHG=2450>human " XBD=857 XHG=713 YBD=2487 YHG=2449>patients " XBD=962 XHG=881 YBD=2480 YHG=2449>with " XBD=1308 XHG=983 YBD=2487 YHG=2449>microangiopathic " XBD=276 XHG=127 YBD=2527 YHG=2496>anaemia. " XBD=508 XHG=319 YBD=2534 YHG=2495>Klibansky " XBD=566 XHG=534 YBD=2527 YHG=2503>et " XBD=649 XHG=592 YBD=2527 YHG=2496>awl. " XBD=760 XHG=675 YBD=2527 YHG=2496>have " XBD=855 XHG=786 YBD=2527 YHG=2496>also " XBD=1040 XHG=882 YBD=2534 YHG=2496>reported " XBD=1307 XHG=1066 YBD=2527 YHG=2496>intravascular |>" XBD=317 XHG=126 YBD=2581 YHG=2542>haemolysis " XBD=442 XHG=359 YBD=2573 YHG=2542>with " XBD=621 XHG=482 YBD=2574 YHG=2543>red-cell " XBD=834 XHG=663 YBD=2574 YHG=2543>crenation " XBD=1048 XHG=875 YBD=2581 YHG=2543>following " XBD=1306 XHG=1088 YBD=2574 YHG=2542>intravenous " XBD=396 XHG=126 YBD=2620 YHG=2589>administration " XBD=461 XHG=421 YBD=2619 YHG=2589>of " XBD=576 XHG=482 YBD=2620 YHG=2589>Echis " XBD=757 XHG=600 YBD=2620 YHG=2589>coloratus " XBD=904 XHG=781 YBD=2620 YHG=2599>venom " XBD=965 XHG=930 YBD=2620 YHG=2589>in " XBD=1083 XHG=990 YBD=2627 YHG=2589>dogs. " XBD=1224 XHG=1124 YBD=2627 YHG=2589>They " XBD=1306 XHG=1248 YBD=2620 YHG=2596>too " XBD=278 XHG=125 YBD=2667 YHG=2636>ascribed " XBD=354 XHG=295 YBD=2667 YHG=2636>the " XBD=611 XHG=373 YBD=2666 YHG=2635>intravascular |>" XBD=819 XHG=628 YBD=2673 YHG=2636>hxmolysis " XBD=875 XHG=839 YBD=2665 YHG=2642>to " XBD=1034 XHG=894 YBD=2673 YHG=2635>damage " XBD=1087 XHG=1052 YBD=2666 YHG=2643>to " XBD=1306 XHG=1107 YBD=2673 YHG=2636>circulating " XBD=183 XHG=124 YBD=2714 YHG=2682>red " XBD=275 XHG=198 YBD=2714 YHG=2682>cells " XBD=475 XHG=290 YBD=2714 YHG=2681>enmeshed " XBD=523 XHG=489 YBD=2712 YHG=2682>in " XBD=631 XHG=536 YBD=2713 YHG=2682>small " XBD=745 XHG=644 YBD=2713 YHG=2682>fibrin " XBD=854 XHG=759 YBD=2718 YHG=2682>clots, " XBD=929 XHG=868 YBD=2712 YHG=2682>but " XBD=1022 XHG=943 YBD=2721 YHG=2682>they " XBD=1235 XHG=1036 YBD=2713 YHG=2682>considered " XBD=1306 XHG=1247 YBD=2714 YHG=2682>the " XBD=363 XHG=124 YBD=2760 YHG=2729>intravascular " XBD=575 XHG=384 YBD=2766 YHG=2728>haemolysis " XBD=632 XHG=597 YBD=2759 YHG=2735>to " XBD=696 XHG=654 YBD=2760 YHG=2730>be " XBD=757 XHG=717 YBD=2759 YHG=2729>of " XBD=886 XHG=774 YBD=2759 YHG=2729>minor " XBD=945 XHG=907 YBD=2759 YHG=2739>or " XBD=1011 XHG=965 YBD=2759 YHG=2739>no " XBD=1248 XHG=1033 YBD=2767 YHG=2729>significance " XBD=1305 XHG=1269 YBD=2759 YHG=2729>in " XBD=180 XHG=123 YBD=2806 YHG=2776>the " XBD=414 XHG=209 YBD=2814 YHG=2775>production " XBD=483 XHG=443 YBD=2805 YHG=2775>of |>" XBD=657 XHG=508 YBD=2806 YHG=2775>anxmia. " XBD=786 XHG=701 YBD=2806 YHG=2775>This " XBD=956 XHG=816 YBD=2813 YHG=2775>opinion " XBD=1011 XHG=985 YBD=2806 YHG=2775>is " XBD=1230 XHG=1042 YBD=2813 YHG=2775>supported " XBD=1306 XHG=1259 YBD=2813 YHG=2776>by " XBD=354 XHG=123 YBD=2853 YHG=2822>observations " XBD=417 XHG=378 YBD=2852 YHG=2822>of " XBD=565 XHG=436 YBD=2852 YHG=2821>human " XBD=732 XHG=588 YBD=2860 YHG=2822>patients " XBD=832 XHG=756 YBD=2852 YHG=2822>who " XBD=923 XHG=855 YBD=2852 YHG=2821>had " XBD=1033 XHG=947 YBD=2853 YHG=2822>been " XBD=1166 XHG=1057 YBD=2853 YHG=2822>bitten " XBD=1235 XHG=1191 YBD=2860 YHG=2823>by " XBD=1302 XHG=1258 YBD=2852 YHG=2822>A. " XBD=324 XHG=123 YBD=2900 YHG=2868>rhodostoma " XBD=415 XHG=348 YBD=2899 YHG=2868>and " XBD=516 XHG=438 YBD=2898 YHG=2868>who " XBD=605 XHG=538 YBD=2899 YHG=2868>had " XBD=785 XHG=628 YBD=2906 YHG=2868>systemic " XBD=987 XHG=807 YBD=2906 YHG=2868>poisoning " XBD=1092 XHG=1010 YBD=2899 YHG=2868>with " XBD=1304 XHG=1115 YBD=2906 YHG=2868>prolonged " XBD=389 XHG=123 YBD=2946 YHG=2915>defibrination.4 " XBD=575 XHG=420 YBD=2945 YHG=2915>Anaemia " XBD=702 XHG=594 YBD=2952 YHG=2915>might " XBD=864 XHG=722 YBD=2953 YHG=2915>develop " XBD=947 XHG=885 YBD=2945 YHG=2915>but " XBD=1060 XHG=966 YBD=2946 YHG=2915>there " XBD=1146 XHG=1080 YBD=2946 YHG=2925>was " XBD=1213 XHG=1167 YBD=2946 YHG=2925>no " XBD=1303 XHG=1234 YBD=2945 YHG=2915>evi- " XBD=229 XHG=123 YBD=2992 YHG=2962>dence " XBD=290 XHG=251 YBD=2992 YHG=2962>of " XBD=485 XHG=309 YBD=2992 YHG=2961>abnormal " XBD=708 XHG=507 YBD=2999 YHG=2961>haemolysis. " XBD=916 XHG=743 YBD=2999 YHG=2961>Repeated " XBD=1019 XHG=938 YBD=2992 YHG=2968>tests " XBD=1102 XHG=1043 YBD=2992 YHG=2961>did " XBD=1186 XHG=1124 YBD=2992 YHG=2969>not " XBD=1304 XHG=1208 YBD=2992 YHG=2961>show " XBD=188 XHG=123 YBD=3045 YHG=3017>any " XBD=357 XHG=209 YBD=3039 YHG=3008>increase " XBD=414 XHG=378 YBD=3037 YHG=3007>in " XBD=821 XHG=435 YBD=3045 YHG=3007>plasma-haemoglobin, " XBD=1088 XHG=843 YBD=3045 YHG=3007>reticulocytes, " XBD=1149 XHG=1111 YBD=3038 YHG=3017>or " XBD=1302 XHG=1171 YBD=3039 YHG=3017>serum- " XBD=295 XHG=123 YBD=3085 YHG=3054>bilirubin. " XBD=410 XHG=334 YBD=3084 YHG=3054>The " XBD=602 XHG=436 YBD=3084 YHG=3053>Schumm " XBD=688 XHG=624 YBD=3084 YHG=3060>test " XBD=777 XHG=712 YBD=3084 YHG=3063>was " XBD=986 XHG=802 YBD=3091 YHG=3053>invariably " XBD=1172 XHG=1008 YBD=3092 YHG=3054>negative. " XBD=1302 XHG=1209 YBD=3084 YHG=3053>Red- " XBD=184 XHG=123 YBD=3130 YHG=3100>cell " XBD=432 XHG=207 YBD=3138 YHG=3100>morphology " XBD=620 XHG=453 YBD=3138 YHG=3099>appeared " XBD=771 XHG=641 YBD=3130 YHG=3100>normal " XBD=829 XHG=794 YBD=3130 YHG=3100>in " XBD=1061 XHG=851 YBD=3130 YHG=3100>blood-films " XBD=1262 XHG=1084 YBD=3138 YHG=3100>(although " XBD=1303 XHG=1284 YBD=3129 YHG=3109>a " XBD=259 XHG=123 YBD=3183 YHG=3146>specific " XBD=387 XHG=271 YBD=3177 YHG=3146>search " XBD=466 XHG=399 YBD=3177 YHG=3156>was " XBD=538 XHG=478 YBD=3177 YHG=3153>not " XBD=648 XHG=550 YBD=3177 YHG=3146>made " XBD=713 XHG=660 YBD=3176 YHG=3146>for " XBD=864 XHG=724 YBD=3176 YHG=3145>red-cell " XBD=1161 XHG=876 YBD=3184 YHG=3146>fragmentation). " XBD=1303 XHG=1189 YBD=3176 YHG=3146>There " XBD=189 XHG=122 YBD=3222 YHG=3200>was " XBD=252 XHG=206 YBD=3222 YHG=3201>no " XBD=583 XHG=268 YBD=3230 YHG=3192>haemoglobinuria, " XBD=666 XHG=600 YBD=3223 YHG=3192>and " XBD=728 XHG=683 YBD=3223 YHG=3202>no " XBD=892 XHG=744 YBD=3223 YHG=3191>increase " XBD=945 XHG=909 YBD=3223 YHG=3193>in " XBD=1098 XHG=961 YBD=3230 YHG=3192>urinary " XBD=1302 XHG=1114 YBD=3223 YHG=3192>urobilino- " XBD=197 XHG=123 YBD=3276 YHG=3246>gen. " XBD=272 XHG=232 YBD=3268 YHG=3238>In " XBD=349 XHG=290 YBD=3269 YHG=3238>the " XBD=528 XHG=367 YBD=3276 YHG=3238>minority " XBD=622 XHG=546 YBD=3269 YHG=3239>who " XBD=698 XHG=641 YBD=3276 YHG=3245>got " XBD=904 XHG=717 YBD=3276 YHG=3237>significant |>" XBD=1075 XHG=923 YBD=3275 YHG=3238>anaemia, " XBD=1214 XHG=1094 YBD=3269 YHG=3238>visible " XBD=1301 XHG=1232 YBD=3268 YHG=3238>dis- " XBD=307 XHG=122 YBD=3315 YHG=3284>coloration " XBD=506 XHG=326 YBD=3322 YHG=3285>suggested " XBD=595 XHG=523 YBD=3315 YHG=3285>that " XBD=679 XHG=612 YBD=3315 YHG=3285>loss " XBD=736 XHG=697 YBD=3316 YHG=3284>of " XBD=809 XHG=749 YBD=3315 YHG=3285>red " XBD=905 XHG=827 YBD=3315 YHG=3285>cells " XBD=996 XHG=924 YBD=3315 YHG=3285>into " XBD=1071 XHG=1013 YBD=3315 YHG=3285>the " XBD=1199 XHG=1089 YBD=3315 YHG=3285>bitten " XBD=1301 XHG=1217 YBD=3314 YHG=3284>limb " XBD=188 XHG=122 YBD=3361 YHG=3340>was " XBD=266 XHG=209 YBD=3361 YHG=3330>the " XBD=396 XHG=286 YBD=3361 YHG=3331>causal " XBD=635 XHG=417 YBD=3361 YHG=3331>mechanism. " XBD=816 XHG=670 YBD=3361 YHG=3330>Patients " XBD=913 XHG=836 YBD=3361 YHG=3331>who " XBD=1020 XHG=933 YBD=3361 YHG=3341>were " XBD=1138 XHG=1041 YBD=3361 YHG=3331>siven " XBD=1216 XHG=1158 YBD=3361 YHG=3331>the " XBD=1301 XHG=1236 YBD=3360 YHG=3330>fib- 1. Holub, D. A., Grumbach, M. M., Tailer, J. W. J. clin. Endocr. Metab. 1958, 18, 1359. Frøland, A., Johnson, S. G., Andresen, P., Dein, E., Sanger, R., Race, R. R. Lancet, 1963, ii, 1121. Nowakowski, H., Lenz, W., Bergman, S., Reitalu, J. Path. Biol., Paris, 1963, 11, 1239. 2. Inouye, E. Studies on Twins. III. Japanese Society for Promotion of Science, 1963 (in Japanese). 3. Klibansky, Ch., Ozcan, E., Joshua, H., Dialdetti, M., Bessler, H., de Vries, A. Toxicon, 1966, 3, 213. 4. Reid, H. A., Thean, P. C., Chan, K. E., Baharom, A. R. Lancet, 1963, i, 617. " XBD=1551 XHG=1394 YBD=356 YHG=318>rinolytic " XBD=1738 XHG=1576 YBD=349 YHG=318>inhibitor " XBD=2044 XHG=1766 YBD=356 YHG=318>e-aminocaproic " XBD=2143 XHG=2070 YBD=349 YHG=318>acid " XBD=2325 XHG=2170 YBD=356 YHG=318>(E.A.C.A.) " XBD=2467 XHG=2352 YBD=355 YHG=317>during " XBD=2542 XHG=2492 YBD=350 YHG=318>the " XBD=1621 XHG=1393 YBD=402 YHG=364>non-clotting " XBD=1744 XHG=1641 YBD=402 YHG=364>phase " XBD=1803 XHG=1764 YBD=395 YHG=365>of defibrination " XBD=2166 XHG=2069 YBD=394 YHG=364>5 had " XBD=2407 XHG=2186 YBD=395 YHG=363>whole-blood " XBD=2540 XHG=2426 YBD=395 YHG=364>haemo- " XBD=1509 XHG=1393 YBD=448 YHG=410>globin " XBD=1634 XHG=1535 YBD=441 YHG=410>levels " XBD=1727 XHG=1661 YBD=440 YHG=410>and " XBD=1958 XHG=1752 YBD=448 YHG=410>packed-cell " XBD=2133 XHG=1984 YBD=441 YHG=410>volumes " XBD=2267 XHG=2160 YBD=441 YHG=410>which " XBD=2349 XHG=2292 YBD=440 YHG=410>did " XBD=2430 XHG=2373 YBD=440 YHG=416>not " XBD=2540 XHG=2453 YBD=441 YHG=410>differ " XBD=1616 XHG=1393 YBD=494 YHG=456>significantly " XBD=1721 XHG=1632 YBD=486 YHG=456>from " XBD=1834 XHG=1739 YBD=487 YHG=456>those " XBD=1887 XHG=1851 YBD=486 YHG=456>in " XBD=2046 XHG=1904 YBD=494 YHG=456>patients " XBD=2123 XHG=2063 YBD=487 YHG=463>not " XBD=2236 XHG=2140 YBD=493 YHG=456>given " XBD=2378 XHG=2252 YBD=487 YHG=463>E.A.C.A. " XBD=2424 XHG=2410 YBD=485 YHG=455>I " XBD=2538 XHG=2441 YBD=486 YHG=455>there- " XBD=1465 XHG=1392 YBD=533 YHG=502>fore " XBD=1598 XHG=1490 YBD=533 YHG=502>doubt " XBD=1772 XHG=1622 YBD=533 YHG=502>whether " XBD=1852 XHG=1796 YBD=533 YHG=503>the " XBD=2099 XHG=1878 YBD=540 YHG=503>experiments " XBD=2162 XHG=2124 YBD=533 YHG=502>of " XBD=2241 XHG=2181 YBD=533 YHG=502>Dr. " XBD=2459 XHG=2263 YBD=539 YHG=502>Rubenberg " XBD=2538 XHG=2481 YBD=533 YHG=503>and " XBD=1444 XHG=1390 YBD=580 YHG=549>his " XBD=1647 XHG=1462 YBD=587 YHG=549>colleagues " XBD=1796 XHG=1665 YBD=587 YHG=549>explain " XBD=1869 XHG=1813 YBD=579 YHG=549>the " XBD=2088 XHG=1886 YBD=587 YHG=549>production " XBD=2143 XHG=2104 YBD=579 YHG=549>of " XBD=2293 XHG=2156 YBD=579 YHG=548>anamia " XBD=2344 XHG=2309 YBD=579 YHG=549>in " XBD=2414 XHG=2359 YBD=579 YHG=548>the " XBD=2537 XHG=2429 YBD=580 YHG=548>micro- " XBD=1605 XHG=1391 YBD=633 YHG=595>angiopathic " XBD=1811 XHG=1620 YBD=633 YHG=595>hasmolytic " XBD=2007 XHG=1827 YBD=633 YHG=596>syndrome " XBD=2057 XHG=2023 YBD=624 YHG=594>in " XBD=2160 XHG=2072 YBD=626 YHG=605>man. H. A. REID. School of Tropical Medicine, Liverpool 3. ANTIBODIES TO GASTRIN |>" XBD=1614 XHG=1435 YBD=909 YHG=872>SIR,-Dr. " XBD=1807 XHG=1641 YBD=910 YHG=872>Stremple " XBD=1896 XHG=1830 YBD=902 YHG=872>and " XBD=1970 XHG=1918 YBD=902 YHG=872>his " XBD=2193 XHG=1994 YBD=902 YHG=872>co-workers " XBD=2312 XHG=2216 YBD=909 YHG=871>(Dec. " XBD=2369 XHG=2339 YBD=906 YHG=872>2, " XBD=2423 XHG=2392 YBD=908 YHG=880>p. " XBD=2531 XHG=2449 YBD=911 YHG=872>1180) " XBD=1497 XHG=1387 YBD=949 YHG=918>write: " XBD=1533 XHG=1513 YBD=931 YHG=918>&dquo; " XBD=1603 XHG=1547 YBD=948 YHG=918>the " XBD=1736 XHG=1616 YBD=955 YHG=918>gastric " XBD=1822 XHG=1749 YBD=948 YHG=918>acid " XBD=2044 XHG=1836 YBD=955 YHG=918>stimulatory " XBD=2190 XHG=2056 YBD=955 YHG=918>portion " XBD=2244 XHG=2206 YBD=948 YHG=917>of " XBD=2322 XHG=2257 YBD=948 YHG=917>this " XBD=2531 XHG=2338 YBD=955 YHG=917>polypeptide " XBD=1569 XHG=1390 YBD=1002 YHG=964>[synthetic " XBD=1717 XHG=1589 YBD=995 YHG=964>human " XBD=1862 XHG=1738 YBD=1002 YHG=964>gastrin " XBD=1908 XHG=1884 YBD=1002 YHG=964>I] " XBD=1958 XHG=1932 YBD=994 YHG=964>is " XBD=2143 XHG=1980 YBD=1002 YHG=964>probably " XBD=2316 XHG=2163 YBD=995 YHG=963>identical " XBD=2369 XHG=2336 YBD=993 YHG=970>to " XBD=2440 XHG=2389 YBD=994 YHG=963>the " XBD=2529 XHG=2458 YBD=995 YHG=965>anti- " XBD=1483 XHG=1387 YBD=1049 YHG=1011>genic " XBD=1725 XHG=1501 YBD=1041 YHG=1010>determinant " XBD=1771 XHG=1740 YBD=1042 YHG=1011>&dquo;. " XBD=1878 XHG=1803 YBD=1041 YHG=1011>The " XBD=2052 XHG=1897 YBD=1048 YHG=1011>&dquo; gastric " XBD=2142 XHG=2068 YBD=1041 YHG=1010>acid " XBD=2365 XHG=2159 YBD=1047 YHG=1010>stimulatory " XBD=2499 XHG=2379 YBD=1048 YHG=1010>portion " XBD=2528 XHG=2512 YBD=1025 YHG=1012>&dquo; " XBD=1602 XHG=1386 YBD=1095 YHG=1057>presumably " XBD=1732 XHG=1630 YBD=1087 YHG=1057>refers " XBD=1796 XHG=1760 YBD=1087 YHG=1064>to " XBD=1880 XHG=1823 YBD=1087 YHG=1057>the " XBD=2108 XHG=1909 YBD=1087 YHG=1056>C-terminal " XBD=2353 XHG=2136 YBD=1095 YHG=1056>tetrapeptide " XBD=2478 XHG=2379 YBD=1088 YHG=1056>amide " XBD=2532 XHG=2501 YBD=1088 YHG=1059>of " XBD=1521 XHG=1385 YBD=1141 YHG=1103>gastrin. " XBD=1646 XHG=1547 YBD=1134 YHG=1102>Since " XBD=1750 XHG=1655 YBD=1133 YHG=1103>Mutt " XBD=1826 XHG=1760 YBD=1133 YHG=1103>and " XBD=1951 XHG=1835 YBD=1141 YHG=1103>Jorpes " XBD=1978 XHG=1966 YBD=1120 YHG=1103>6 " XBD=2073 XHG=1990 YBD=1133 YHG=1103>have " XBD=2200 XHG=2084 YBD=1133 YHG=1103>shown " XBD=2279 XHG=2208 YBD=1133 YHG=1103>that " XBD=2344 XHG=2288 YBD=1134 YHG=1103>the " XBD=2528 XHG=2353 YBD=1134 YHG=1102>C-terminal " XBD=1610 XHG=1386 YBD=1187 YHG=1149>tetrapeptide " XBD=1743 XHG=1632 YBD=1179 YHG=1149>amide " XBD=1805 XHG=1766 YBD=1179 YHG=1149>of " XBD=2376 XHG=1824 YBD=1187 YHG=1148>cholecystokinin-pancreozymin " XBD=2422 XHG=2397 YBD=1179 YHG=1148>is " XBD=2527 XHG=2441 YBD=1188 YHG=1150>prob- " XBD=1464 XHG=1386 YBD=1233 YHG=1195>ably " XBD=1635 XHG=1479 YBD=1227 YHG=1195>identical " XBD=1686 XHG=1651 YBD=1226 YHG=1202>to " XBD=1774 XHG=1702 YBD=1226 YHG=1195>that " XBD=1828 XHG=1789 YBD=1226 YHG=1196>of " XBD=1976 XHG=1839 YBD=1234 YHG=1196>gastrin, " XBD=2178 XHG=1992 YBD=1227 YHG=1195>antibodies " XBD=2228 XHG=2194 YBD=1226 YHG=1203>to " XBD=2366 XHG=2244 YBD=1233 YHG=1195>gastrin " XBD=2481 XHG=2381 YBD=1227 YHG=1196>would " XBD=2527 XHG=2494 YBD=1228 YHG=1197>be " XBD=1548 XHG=1386 YBD=1280 YHG=1241>expected " XBD=1604 XHG=1570 YBD=1272 YHG=1249>to " XBD=1825 XHG=1627 YBD=1273 YHG=1248>cross-react " XBD=1927 XHG=1845 YBD=1273 YHG=1242>with " XBD=2492 XHG=1944 YBD=1280 YHG=1242>cholecystokinin-pancreozymin, " XBD=2530 XHG=2507 YBD=1274 YHG=1243>if " XBD=1443 XHG=1385 YBD=1319 YHG=1287>the " XBD=1672 XHG=1460 YBD=1326 YHG=1289>assumption " XBD=1728 XHG=1688 YBD=1319 YHG=1289>of " XBD=1803 XHG=1741 YBD=1319 YHG=1289>Dr. " XBD=1991 XHG=1825 YBD=1327 YHG=1288>Stremple " XBD=2073 XHG=2008 YBD=1320 YHG=1289>and " XBD=2142 XHG=2090 YBD=1320 YHG=1289>his " XBD=2357 XHG=2160 YBD=1320 YHG=1289>co-workers " XBD=2466 XHG=2374 YBD=1320 YHG=1289>about " XBD=2526 XHG=2480 YBD=1321 YHG=1290>the " XBD=1553 XHG=1385 YBD=1372 YHG=1335>antigenic " XBD=1793 XHG=1569 YBD=1366 YHG=1335>determinant " XBD=1835 XHG=1808 YBD=1366 YHG=1335>is " XBD=1988 XHG=1852 YBD=1366 YHG=1342>correct. MORTON I. GROSSMAN. Veterans Administration Center, Los Angles, California 90073. Obituary " XBD=1842 XHG=1675 YBD=1727 YHG=1697>HENRY " XBD=2008 XHG=1866 YBD=1727 YHG=1696>CECIL " XBD=2260 XHG=2028 YBD=1735 YHG=1696>JENNINGS " XBD=1712 XHG=1611 YBD=1786 YHG=1753>M.A., " XBD=1814 XHG=1729 YBD=1781 YHG=1753>M.B. " XBD=1944 XHG=1832 YBD=1786 YHG=1753>Lond., " XBD=2049 XHG=1962 YBD=1781 YHG=1753>B.Sc. " XBD=2180 XHG=2067 YBD=1787 YHG=1753>Oxon., " XBD=2315 XHG=2196 YBD=1781 YHG=1753>D.P.H. " XBD=1498 XHG=1431 YBD=1846 YHG=1812>Dr. " XBD=1577 XHG=1527 YBD=1846 YHG=1812>H. " XBD=1649 XHG=1605 YBD=1846 YHG=1812>C. " XBD=1865 XHG=1677 YBD=1854 YHG=1812>Jennings, " XBD=2063 XHG=1892 YBD=1854 YHG=1812>formerly " XBD=2224 XHG=2089 YBD=1854 YHG=1819>county " XBD=2397 XHG=2248 YBD=1846 YHG=1812>medical " XBD=2526 XHG=2421 YBD=1847 YHG=1813>officer " XBD=1439 XHG=1381 YBD=1898 YHG=1864>for " XBD=1725 XHG=1471 YBD=1905 YHG=1864>Oxfordshire, " XBD=1842 XHG=1757 YBD=1897 YHG=1864>died " XBD=1908 XHG=1873 YBD=1898 YHG=1871>at " XBD=1994 XHG=1938 YBD=1898 YHG=1864>his " XBD=2135 XHG=2025 YBD=1898 YHG=1864>home " XBD=2200 XHG=2165 YBD=1898 YHG=1872>at " XBD=2458 XHG=2230 YBD=1905 YHG=1865>Eastbourne, " XBD=2526 XHG=2485 YBD=1899 YHG=1876>on " XBD=1479 XHG=1381 YBD=1951 YHG=1916>Nov. " XBD=1545 XHG=1503 YBD=1949 YHG=1917>19 " XBD=1600 XHG=1565 YBD=1949 YHG=1923>at " XBD=1682 XHG=1619 YBD=1950 YHG=1916>the " XBD=1766 XHG=1701 YBD=1958 YHG=1926>age " XBD=1827 XHG=1785 YBD=1949 YHG=1917>of " XBD=1898 XHG=1842 YBD=1950 YHG=1917>74. " XBD=1479 XHG=1425 YBD=2009 YHG=1978>He " XBD=1664 XHG=1512 YBD=2009 YHG=1978>received " XBD=1750 XHG=1697 YBD=2008 YHG=1978>his " XBD=1924 XHG=1784 YBD=2009 YHG=1977>medical " XBD=2135 XHG=1958 YBD=2009 YHG=1978>education " XBD=2200 XHG=2168 YBD=2009 YHG=1985>at " XBD=2362 XHG=2233 YBD=2009 YHG=1978>Oxford " XBD=2453 XHG=2392 YBD=2009 YHG=1978>and " XBD=2524 XHG=2484 YBD=2010 YHG=1979>St. " XBD=1561 XHG=1379 YBD=2056 YHG=2025>Thomas’s " XBD=1755 XHG=1585 YBD=2063 YHG=2024>Hospital, " XBD=1887 XHG=1776 YBD=2056 YHG=2025>where " XBD=1948 XHG=1906 YBD=2056 YHG=2025>he " XBD=2128 XHG=1970 YBD=2063 YHG=2025>qualified " XBD=2183 XHG=2149 YBD=2055 YHG=2025>in " XBD=2298 XHG=2206 YBD=2056 YHG=2026>1915. " XBD=2459 XHG=2335 YBD=2064 YHG=2025>During " XBD=2526 XHG=2477 YBD=2057 YHG=2025>the " XBD=1525 XHG=1381 YBD=2103 YHG=2072>1914-18 " XBD=1618 XHG=1552 YBD=2102 YHG=2081>war " XBD=1687 XHG=1644 YBD=2102 YHG=2071>he " XBD=1830 XHG=1713 YBD=2103 YHG=2071>served " XBD=1891 XHG=1856 YBD=2102 YHG=2072>in " XBD=1973 XHG=1916 YBD=2103 YHG=2072>the " XBD=2103 XHG=1998 YBD=2110 YHG=2072>Royal " XBD=2237 XHG=2129 YBD=2110 YHG=2072>Navy, " XBD=2328 XHG=2263 YBD=2103 YHG=2072>and " XBD=2524 XHG=2353 YBD=2104 YHG=2072>afterwards " XBD=1521 XHG=1378 YBD=2149 YHG=2118>decided " XBD=1577 XHG=1542 YBD=2149 YHG=2125>to " XBD=1672 XHG=1597 YBD=2149 YHG=2118>take " XBD=1739 XHG=1693 YBD=2156 YHG=2128>up " XBD=1779 XHG=1761 YBD=2149 YHG=2128>a " XBD=1910 XHG=1801 YBD=2149 YHG=2128>career " XBD=1966 XHG=1930 YBD=2148 YHG=2119>in " XBD=2230 XHG=1985 YBD=2157 YHG=2118>public-health " XBD=2350 XHG=2250 YBD=2155 YHG=2119>work, " XBD=2525 XHG=2371 YBD=2157 YHG=2119>obtaining " XBD=1435 XHG=1376 YBD=2195 YHG=2164>the " XBD=1558 XHG=1451 YBD=2195 YHG=2172>D.P.H. " XBD=1612 XHG=1578 YBD=2194 YHG=2165>in " XBD=1725 XHG=1632 YBD=2195 YHG=2165>1920. " XBD=1853 XHG=1756 YBD=2196 YHG=2165>After " XBD=1994 XHG=1871 YBD=2196 YHG=2165>service " XBD=2092 XHG=2011 YBD=2195 YHG=2165>with " XBD=2165 XHG=2108 YBD=2196 YHG=2165>the " XBD=2289 XHG=2182 YBD=2196 YHG=2165>Leeds " XBD=2383 XHG=2307 YBD=2203 YHG=2165>City " XBD=2524 XHG=2399 YBD=2196 YHG=2165>Council " XBD=1420 XHG=1376 YBD=2242 YHG=2211>he " XBD=1501 XHG=1435 YBD=2242 YHG=2221>was " XBD=1701 XHG=1517 YBD=2250 YHG=2211>appointed " XBD=1842 XHG=1717 YBD=2250 YHG=2219>county " XBD=1998 XHG=1857 YBD=2242 YHG=2211>medical " XBD=2126 XHG=2014 YBD=2243 YHG=2212>officer " XBD=2193 XHG=2141 YBD=2243 YHG=2212>for " XBD=2364 XHG=2208 YBD=2249 YHG=2212>Holland, " XBD=2441 XHG=2379 YBD=2242 YHG=2211>and " XBD=2523 XHG=2455 YBD=2243 YHG=2211>then " XBD=1466 XHG=1375 YBD=2289 YHG=2265>went " XBD=1528 XHG=1482 YBD=2289 YHG=2268>on " XBD=1580 XHG=1545 YBD=2289 YHG=2265>to " XBD=1672 XHG=1597 YBD=2289 YHG=2258>take " XBD=1736 XHG=1689 YBD=2297 YHG=2268>up " XBD=1806 XHG=1753 YBD=2290 YHG=2258>his " XBD=2057 XHG=1824 YBD=2297 YHG=2258>appointment " XBD=2109 XHG=2074 YBD=2289 YHG=2258>in " XBD=2355 XHG=2127 YBD=2295 YHG=2258>Oxfordshire, " XBD=2474 XHG=2372 YBD=2289 YHG=2258>which " XBD=2523 XHG=2488 YBD=2289 YHG=2258>he " XBD=1455 XHG=1374 YBD=2336 YHG=2305>held " XBD=1533 XHG=1479 YBD=2336 YHG=2305>for " XBD=1596 XHG=1557 YBD=2335 YHG=2306>21 " XBD=1728 XHG=1623 YBD=2343 YHG=2315>years. " XBD=1809 XHG=1768 YBD=2336 YHG=2306>In " XBD=1918 XHG=1836 YBD=2336 YHG=2306>1935 " XBD=1986 XHG=1943 YBD=2336 YHG=2306>he " XBD=2088 XHG=2010 YBD=2336 YHG=2305>took " XBD=2168 XHG=2112 YBD=2336 YHG=2305>the " XBD=2322 XHG=2193 YBD=2336 YHG=2305>Oxford " XBD=2473 XHG=2347 YBD=2343 YHG=2305>degrees " XBD=2525 XHG=2494 YBD=2336 YHG=2305>of " XBD=1456 XHG=1373 YBD=2383 YHG=2359>B.sc. " XBD=1546 XHG=1478 YBD=2383 YHG=2352>and " XBD=1630 XHG=1564 YBD=2383 YHG=2360>B.A. " XBD=1734 XHG=1651 YBD=2383 YHG=2352>with " XBD=1901 XHG=1751 YBD=2383 YHG=2352>honours " XBD=1955 XHG=1920 YBD=2383 YHG=2352>in " XBD=2103 XHG=1974 YBD=2383 YHG=2352>natural " XBD=2251 XHG=2123 YBD=2384 YHG=2352>science " XBD=2335 XHG=2270 YBD=2383 YHG=2352>and " XBD=2426 XHG=2353 YBD=2383 YHG=2352>four " XBD=2521 XHG=2443 YBD=2390 YHG=2361>years " XBD=1455 XHG=1373 YBD=2430 YHG=2399>later " XBD=1658 XHG=1469 YBD=2437 YHG=2399>proceeded " XBD=1706 XHG=1671 YBD=2430 YHG=2406>to " XBD=1794 XHG=1719 YBD=2429 YHG=2407>M.A. " XBD=1885 XHG=1830 YBD=2429 YHG=2399>He " XBD=1963 XHG=1898 YBD=2430 YHG=2409>was " XBD=2019 XHG=1977 YBD=2429 YHG=2408>an " XBD=2199 XHG=2033 YBD=2429 YHG=2399>examiner " XBD=2245 XHG=2211 YBD=2429 YHG=2399>in " XBD=2370 XHG=2257 YBD=2437 YHG=2399>public " XBD=2486 XHG=2382 YBD=2429 YHG=2398>health " XBD=2522 XHG=2496 YBD=2428 YHG=2403>at " XBD=1507 XHG=1374 YBD=2476 YHG=2445>Oxford " XBD=1731 XHG=1526 YBD=2483 YHG=2445>University. " XBD=1801 XHG=1760 YBD=2475 YHG=2445>In " XBD=1875 XHG=1818 YBD=2476 YHG=2445>the " XBD=2041 XHG=1895 YBD=2476 YHG=2446>1939-45 " XBD=2126 XHG=2059 YBD=2475 YHG=2454>war " XBD=2184 XHG=2142 YBD=2476 YHG=2445>he " XBD=2316 XHG=2202 YBD=2476 YHG=2445>served " XBD=2366 XHG=2333 YBD=2476 YHG=2455>as " XBD=2396 XHG=2379 YBD=2475 YHG=2454>a " XBD=2521 XHG=2409 YBD=2476 YHG=2444>colonel " XBD=1408 XHG=1372 YBD=2522 YHG=2492>in " XBD=1490 XHG=1433 YBD=2523 YHG=2492>the " XBD=1629 XHG=1516 YBD=2523 YHG=2492>Home " XBD=1786 XHG=1657 YBD=2523 YHG=2491>Guard. " XBD=1921 XHG=1825 YBD=2523 YHG=2492>After " XBD=1997 XHG=1946 YBD=2522 YHG=2491>his " XBD=2214 XHG=2023 YBD=2523 YHG=2492>retirement " XBD=2273 XHG=2238 YBD=2522 YHG=2492>in " XBD=2380 XHG=2300 YBD=2522 YHG=2492>1953 " XBD=2444 XHG=2403 YBD=2522 YHG=2491>he " XBD=2520 XHG=2466 YBD=2522 YHG=2500>was " XBD=1546 XHG=1372 YBD=2569 YHG=2538>chairman " XBD=1612 XHG=1573 YBD=2570 YHG=2539>of " XBD=1693 XHG=1636 YBD=2569 YHG=2539>the " XBD=1881 XHG=1721 YBD=2577 YHG=2538>Banbury " XBD=2051 XHG=1908 YBD=2577 YHG=2538>hospital " XBD=2309 XHG=2078 YBD=2576 YHG=2546>management " XBD=2519 XHG=2336 YBD=2569 YHG=2538>committee. " XBD=1486 XHG=1372 YBD=2617 YHG=2585>Three " XBD=1602 XHG=1509 YBD=2624 YHG=2595>years " XBD=1687 XHG=1625 YBD=2623 YHG=2594>ago " XBD=1752 XHG=1709 YBD=2616 YHG=2585>he " XBD=1897 XHG=1774 YBD=2617 YHG=2586>moved " XBD=1953 XHG=1918 YBD=2616 YHG=2593>to " XBD=2193 XHG=1976 YBD=2616 YHG=2585>Eastbourne. " XBD=1478 XHG=1415 YBD=2662 YHG=2632>Dr. " XBD=1661 XHG=1500 YBD=2670 YHG=2632>Jennings " XBD=1790 XHG=1682 YBD=2662 YHG=2631>leaves " XBD=1828 XHG=1810 YBD=2662 YHG=2641>a " XBD=1968 XHG=1848 YBD=2662 YHG=2632>widow " XBD=2053 XHG=1987 YBD=2663 YHG=2631>and " XBD=2138 XHG=2072 YBD=2662 YHG=2638>two " XBD=2344 XHG=2158 YBD=2669 YHG=2631>daughters. " XBD=1468 XHG=1418 YBD=2729 YHG=2696>N. " XBD=1522 XHG=1491 YBD=2735 YHG=2695>J. " XBD=1586 XHG=1545 YBD=2729 YHG=2695>E. " XBD=1745 XHG=1608 YBD=2729 YHG=2695>writes: " XBD=1513 XHG=1415 YBD=2786 YHG=2755>&dquo; Dr. " XBD=1700 XHG=1539 YBD=2792 YHG=2755>Jennings " XBD=1791 XHG=1725 YBD=2784 YHG=2754>will " XBD=1856 XHG=1815 YBD=2785 YHG=2755>be " XBD=2110 XHG=1880 YBD=2785 YHG=2753>remembered " XBD=2184 XHG=2132 YBD=2784 YHG=2754>for " XBD=2257 XHG=2206 YBD=2784 YHG=2754>his " XBD=2520 XHG=2281 YBD=2792 YHG=2753>championship " XBD=1409 XHG=1369 YBD=2831 YHG=2801>of " XBD=1479 XHG=1421 YBD=2831 YHG=2801>the " XBD=1555 XHG=1494 YBD=2832 YHG=2811>use " XBD=1610 XHG=1571 YBD=2832 YHG=2801>of " XBD=1755 XHG=1622 YBD=2839 YHG=2800>general " XBD=2002 XHG=1771 YBD=2838 YHG=2801>practitioners " XBD=2053 XHG=2019 YBD=2830 YHG=2800>in " XBD=2126 XHG=2069 YBD=2831 YHG=2801>the " XBD=2382 XHG=2141 YBD=2838 YHG=2800>public-health " XBD=2519 XHG=2398 YBD=2831 YHG=2800>service. " XBD=1424 XHG=1369 YBD=2878 YHG=2847>He " XBD=1541 XHG=1442 YBD=2879 YHG=2847>made " XBD=1619 XHG=1558 YBD=2878 YHG=2847>full " XBD=1697 XHG=1637 YBD=2878 YHG=2857>use " XBD=1754 XHG=1714 YBD=2878 YHG=2847>of " XBD=1853 XHG=1768 YBD=2878 YHG=2847>their " XBD=2011 XHG=1871 YBD=2878 YHG=2847>services " XBD=2063 XHG=2029 YBD=2877 YHG=2847>in " XBD=2271 XHG=2080 YBD=2885 YHG=2847>preference " XBD=2321 XHG=2288 YBD=2877 YHG=2853>to " XBD=2521 XHG=2338 YBD=2885 YHG=2846>appointing " XBD=1578 XHG=1369 YBD=2925 YHG=2894>whole-time " XBD=1686 XHG=1600 YBD=2925 YHG=2894>staff. " XBD=1799 XHG=1723 YBD=2924 YHG=2894>The " XBD=1923 XHG=1821 YBD=2924 YHG=2894>strain " XBD=1983 XHG=1944 YBD=2925 YHG=2894>of " XBD=2058 XHG=2001 YBD=2925 YHG=2894>the " XBD=2145 XHG=2078 YBD=2925 YHG=2903>war " XBD=2257 XHG=2166 YBD=2932 YHG=2903>years " XBD=2342 XHG=2279 YBD=2924 YHG=2903>was " XBD=2397 XHG=2363 YBD=2924 YHG=2900>to " XBD=2522 XHG=2417 YBD=2931 YHG=2893>justify " XBD=1421 XHG=1368 YBD=2971 YHG=2939>his " XBD=1532 XHG=1443 YBD=2978 YHG=2941>good " XBD=1730 XHG=1553 YBD=2978 YHG=2941>judgment " XBD=1786 XHG=1752 YBD=2970 YHG=2940>in " XBD=1879 XHG=1807 YBD=2970 YHG=2940>that " XBD=1942 XHG=1901 YBD=2971 YHG=2950>an " XBD=2127 XHG=1964 YBD=2978 YHG=2941>adequate " XBD=2387 XHG=2147 YBD=2978 YHG=2939>public-health " XBD=2521 XHG=2408 YBD=2970 YHG=2940>service " XBD=1435 XHG=1368 YBD=3017 YHG=2996>was " XBD=1535 XHG=1461 YBD=3017 YHG=2987>well " XBD=1777 XHG=1561 YBD=3017 YHG=2986>maintained. " XBD=1880 XHG=1817 YBD=3017 YHG=2986>His " XBD=2083 XHG=1906 YBD=3017 YHG=2986>insistence " XBD=2179 XHG=2107 YBD=3017 YHG=2986>that " XBD=2259 XHG=2203 YBD=3017 YHG=2986>the " XBD=2410 XHG=2284 YBD=3024 YHG=2986>general " XBD=2520 XHG=2433 YBD=3024 YHG=2996>prac- " XBD=1504 XHG=1367 YBD=3063 YHG=3032>titioner " XBD=1615 XHG=1524 YBD=3063 YHG=3039>must " XBD=1678 XHG=1636 YBD=3064 YHG=3034>be " XBD=1716 XHG=1698 YBD=3063 YHG=3043>a " XBD=1799 XHG=1736 YBD=3070 YHG=3033>key " XBD=1923 XHG=1817 YBD=3070 YHG=3032>figure " XBD=1978 XHG=1943 YBD=3063 YHG=3032>in " XBD=2054 XHG=1998 YBD=3063 YHG=3033>the " XBD=2316 XHG=2073 YBD=3071 YHG=3032>public-health " XBD=2453 XHG=2336 YBD=3063 YHG=3032>service " XBD=2520 XHG=2471 YBD=3063 YHG=3032>led " XBD=1403 XHG=1367 YBD=3109 YHG=3085>to " XBD=1447 XHG=1429 YBD=3109 YHG=3089>a " XBD=1577 XHG=1473 YBD=3109 YHG=3079>much " XBD=1705 XHG=1602 YBD=3111 YHG=3079>wider " XBD=1791 XHG=1731 YBD=3109 YHG=3089>use " XBD=1855 XHG=1816 YBD=3109 YHG=3078>of " XBD=1933 XHG=1876 YBD=3109 YHG=3079>the " XBD=2071 XHG=1959 YBD=3109 YHG=3078>health " XBD=2225 XHG=2096 YBD=3110 YHG=3079>visitors " XBD=2296 XHG=2252 YBD=3117 YHG=3079>by " XBD=2374 XHG=2319 YBD=3109 YHG=3079>the " XBD=2520 XHG=2398 YBD=3116 YHG=3078>general " XBD=1600 XHG=1367 YBD=3163 YHG=3124>practitioners " XBD=1655 XHG=1619 YBD=3155 YHG=3125>in " XBD=1730 XHG=1673 YBD=3155 YHG=3125>the " XBD=1910 XHG=1748 YBD=3163 YHG=3131>post-war " XBD=2032 XHG=1927 YBD=3163 YHG=3134>years, " XBD=2117 XHG=2051 YBD=3156 YHG=3125>and " XBD=2200 XHG=2135 YBD=3156 YHG=3125>this " XBD=2253 XHG=2218 YBD=3155 YHG=3125>in " XBD=2311 XHG=2270 YBD=3155 YHG=3126>its " XBD=2404 XHG=2329 YBD=3155 YHG=3132>turn " XBD=2471 XHG=2421 YBD=3156 YHG=3125>led " XBD=2520 XHG=2488 YBD=3156 YHG=3132>to " XBD=1425 XHG=1367 YBD=3201 YHG=3171>the " XBD=1704 XHG=1451 YBD=3202 YHG=3171>establishment " XBD=1769 XHG=1730 YBD=3201 YHG=3171>of " XBD=1808 XHG=1791 YBD=3200 YHG=3180>a " XBD=2079 XHG=1833 YBD=3201 YHG=3171>health-visitor " XBD=2216 XHG=2104 YBD=3202 YHG=3171>school " XBD=2276 XHG=2241 YBD=3202 YHG=3171>in " XBD=2518 XHG=2301 YBD=3202 YHG=3171>Oxfordshire. " XBD=1422 XHG=1367 YBD=3247 YHG=3217>He " XBD=1511 XHG=1445 YBD=3247 YHG=3226>was " XBD=1553 XHG=1536 YBD=3247 YHG=3226>a " XBD=1651 XHG=1576 YBD=3255 YHG=3224>past " XBD=1845 XHG=1674 YBD=3247 YHG=3217>chairman " XBD=1908 XHG=1868 YBD=3247 YHG=3217>of " XBD=1983 XHG=1926 YBD=3247 YHG=3218>the " XBD=2142 XHG=2007 YBD=3255 YHG=3217>County " XBD=2310 XHG=2164 YBD=3248 YHG=3217>Medical " XBD=2464 XHG=2333 YBD=3248 YHG=3218>Officers " XBD=2522 XHG=2486 YBD=3248 YHG=3218>of " XBD=1493 XHG=1367 YBD=3293 YHG=3262>Health " XBD=1682 XHG=1514 YBD=3301 YHG=3262>Society.&dquo; " XBD=1472 XHG=1415 YBD=3358 YHG=3325>M. " XBD=1526 XHG=1494 YBD=3364 YHG=3324>J. " XBD=1586 XHG=1547 YBD=3359 YHG=3325>P. " XBD=1672 XHG=1608 YBD=3360 YHG=3325>has " XBD=1774 XHG=1694 YBD=3358 YHG=3333>sent " XBD=1855 XHG=1794 YBD=3359 YHG=3325>the " XBD=2061 XHG=1876 YBD=3367 YHG=3325>following " XBD=2245 XHG=2080 YBD=3367 YHG=3326>personal " XBD=2366 XHG=2264 YBD=3360 YHG=3327>lines: " XBD=1565 XHG=1411 YBD=3422 YHG=3384>&dquo; Henry " XBD=1753 XHG=1592 YBD=3422 YHG=3385>Jennings " XBD=1848 XHG=1782 YBD=3415 YHG=3394>was " XBD=1933 XHG=1876 YBD=3415 YHG=3385>the " XBD=2033 XHG=1961 YBD=3415 YHG=3385>first " XBD=2228 XHG=2060 YBD=3415 YHG=3385>chairman " XBD=2293 XHG=2255 YBD=3416 YHG=3385>of " XBD=2369 XHG=2315 YBD=3416 YHG=3385>the " XBD=2516 XHG=2396 YBD=3417 YHG=3385>Oxford " XBD=1508 XHG=1365 YBD=3461 YHG=3430>medical " XBD=1662 XHG=1533 YBD=3461 YHG=3431>officers " XBD=1727 XHG=1687 YBD=3461 YHG=3430>of " XBD=1860 XHG=1746 YBD=3461 YHG=3430>health " XBD=1998 XHG=1881 YBD=3461 YHG=3431>liaison " XBD=2220 XHG=2019 YBD=3467 YHG=3432>committee, " XBD=2305 XHG=2241 YBD=3462 YHG=3432>and " XBD=2349 XHG=2325 YBD=3461 YHG=3432>it " XBD=2393 XHG=2368 YBD=3462 YHG=3431>is " XBD=2445 XHG=2413 YBD=3462 YHG=3438>to " XBD=2514 XHG=2467 YBD=3462 YHG=3432>his " XBD=1471 XHG=1365 YBD=3507 YHG=3476>credit " XBD=1575 XHG=1503 YBD=3507 YHG=3476>that " XBD=1691 XHG=1607 YBD=3507 YHG=3477>such " XBD=1741 XHG=1723 YBD=3506 YHG=3486>a " XBD=1887 XHG=1773 YBD=3514 YHG=3477>happy " XBD=2133 XHG=1918 YBD=3515 YHG=3476>relationship " XBD=2223 XHG=2165 YBD=3508 YHG=3477>has " XBD=2368 XHG=2254 YBD=3515 YHG=3477>always " XBD=2514 XHG=2399 YBD=3508 YHG=3477>existed " XBD=1518 XHG=1364 YBD=3553 YHG=3522>between " XBD=1604 XHG=1548 YBD=3552 YHG=3522>the " XBD=1883 XHG=1635 YBD=3560 YHG=3522>public-health " XBD=1979 XHG=1913 YBD=3552 YHG=3522>and " XBD=2274 XHG=2010 YBD=3560 YHG=3522>hospital-board " XBD=2379 XHG=2303 YBD=3553 YHG=3523>staff " XBD=2435 XHG=2403 YBD=3553 YHG=3523>in " XBD=2513 XHG=2462 YBD=3555 YHG=3523>the " XBD=1497 XHG=1364 YBD=3598 YHG=3568>Oxford " XBD=1652 XHG=1526 YBD=3605 YHG=3568>region. " XBD=1741 XHG=1694 YBD=3598 YHG=3568>As " XBD=1942 XHG=1771 YBD=3598 YHG=3568>chairman " XBD=2009 XHG=1970 YBD=3598 YHG=3568>of " XBD=2090 XHG=2034 YBD=3598 YHG=3568>the " XBD=2275 XHG=2119 YBD=3606 YHG=3569>Banbury " XBD=2448 XHG=2301 YBD=3605 YHG=3568>H.M.C., " XBD=2513 XHG=2473 YBD=3600 YHG=3569>he " XBD=1554 XHG=1363 YBD=3644 YHG=3614>undertook " XBD=1625 XHG=1573 YBD=3643 YHG=3613>his " XBD=1922 XHG=1647 YBD=3650 YHG=3613>responsibilities " XBD=2026 XHG=1944 YBD=3643 YHG=3613>with " XBD=2137 XHG=2046 YBD=3650 YHG=3621>great " XBD=2404 XHG=2157 YBD=3651 YHG=3614>thoroughness, " XBD=2512 XHG=2425 YBD=3645 YHG=3615>made 5. Reid, H. A. ibid. 1965, ii, 5. 6. Mutt, V., Jorpes, J. E. Biochem. biophys. Res. Comm. 1967, 26, 392.

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Page 1: TWINS WITH KLINEFELTER'S SYNDROME

1424

TWINS WITH KLINEFELTER’S SYNDROME

|>" XBD=374 XHG=193 YBD=412 YHG=375>SiR,―We " XBD=456 XHG=389 YBD=405 YHG=375>add " XBD=552 XHG=472 YBD=405 YHG=375>here " XBD=586 XHG=568 YBD=405 YHG=384>a " XBD=718 XHG=601 YBD=406 YHG=375>fourth " XBD=768 XHG=733 YBD=406 YHG=382>to " XBD=840 XHG=783 YBD=406 YHG=375>the " XBD=950 XHG=855 YBD=407 YHG=376>three " XBD=1054 XHG=965 YBD=413 YHG=375>pairs " XBD=1109 XHG=1069 YBD=406 YHG=375>of " XBD=1329 XHG=1120 YBD=406 YHG=375>concordant" XBD=383 XHG=146 YBD=459 YHG=421>monozygotic " XBD=525 XHG=426 YBD=451 YHG=421>twins " XBD=652 XHG=569 YBD=451 YHG=421>with " XBD=924 XHG=696 YBD=453 YHG=421>Klinefelter’s " XBD=1150 XHG=969 YBD=460 YHG=421>syndrome " XBD=1329 XHG=1194 YBD=459 YHG=421>already" XBD=330 XHG=145 YBD=506 YHG=467>reported. " XBD=330 XHG=319 YBD=484 YHG=467>1" XBD=266 XHG=189 YBD=560 YHG=529>The " XBD=358 XHG=283 YBD=559 YHG=529>first " XBD=457 XHG=374 YBD=559 YHG=528>twin " XBD=542 XHG=475 YBD=560 YHG=538>was " XBD=731 XHG=561 YBD=561 YHG=529>delivered " XBD=794 XHG=749 YBD=568 YHG=530>by " XBD=924 XHG=810 YBD=560 YHG=536>vertex " XBD=1170 XHG=941 YBD=567 YHG=529>presentation " XBD=1328 XHG=1188 YBD=567 YHG=529>(weight" XBD=232 XHG=145 YBD=607 YHG=576>3200 " XBD=307 XHG=247 YBD=613 YHG=575>g.), " XBD=392 XHG=324 YBD=606 YHG=575>and " XBD=466 XHG=407 YBD=606 YHG=575>the " XBD=608 XHG=482 YBD=607 YHG=576>second " XBD=670 XHG=625 YBD=614 YHG=576>by " XBD=809 XHG=686 YBD=607 YHG=576>breech " XBD=1052 XHG=823 YBD=614 YHG=576>presentation " XBD=1150 XHG=1067 YBD=607 YHG=575>with " XBD=1327 XHG=1165 YBD=614 YHG=575>asphyxia" XBD=283 XHG=145 YBD=659 YHG=621>(weight " XBD=388 XHG=301 YBD=652 YHG=622>3040 " XBD=466 XHG=406 YBD=659 YHG=621>g.), " XBD=518 XHG=485 YBD=652 YHG=629>at " XBD=578 XHG=535 YBD=652 YHG=623>39 " XBD=716 XHG=596 YBD=653 YHG=622>weeks’ " XBD=908 XHG=734 YBD=660 YHG=622>gestation. " XBD=1096 XHG=944 YBD=660 YHG=621>Physical " XBD=1181 XHG=1114 YBD=652 YHG=621>and " XBD=1326 XHG=1199 YBD=652 YHG=622>mental" XBD=384 XHG=144 YBD=705 YHG=667>development " XBD=471 XHG=403 YBD=698 YHG=676>was " XBD=663 XHG=492 YBD=699 YHG=667>retarded: " XBD=742 XHG=684 YBD=698 YHG=668>the " XBD=833 XHG=760 YBD=698 YHG=667>first " XBD=934 XHG=852 YBD=698 YHG=667>twin " XBD=1020 XHG=953 YBD=698 YHG=668>had " XBD=1106 XHG=1040 YBD=699 YHG=674>two " XBD=1271 XHG=1127 YBD=698 YHG=668>seizures " XBD=1326 XHG=1292 YBD=698 YHG=674>at" XBD=204 XHG=143 YBD=751 YHG=722>age " XBD=240 XHG=219 YBD=743 YHG=714>2 " XBD=362 XHG=255 YBD=751 YHG=722>years. " XBD=455 XHG=409 YBD=743 YHG=713>At " XBD=532 XHG=472 YBD=751 YHG=723>age " XBD=591 XHG=551 YBD=744 YHG=715>16 " XBD=692 XHG=608 YBD=745 YHG=713>both " XBD=805 XHG=707 YBD=744 YHG=713>twins " XBD=889 XHG=821 YBD=744 YHG=713>had " XBD=998 XHG=905 YBD=744 YHG=713>these " XBD=1144 XHG=1015 YBD=744 YHG=713>clinical " XBD=1323 XHG=1161 YBD=744 YHG=713>features:" XBD=339 XHG=142 YBD=790 YHG=758>eunuchoid " XBD=479 XHG=369 YBD=796 YHG=759>build, " XBD=806 XHG=509 YBD=798 YHG=759>underdeveloped " XBD=1020 XHG=836 YBD=797 YHG=760>secondary " XBD=1106 XHG=1049 YBD=790 YHG=769>sex " XBD=1324 XHG=1136 YBD=791 YHG=759>character-" XBD=245 XHG=141 YBD=842 YHG=805>istics, " XBD=367 XHG=263 YBD=844 YHG=805>slight " XBD=655 XHG=383 YBD=844 YHG=807>gynascomastia, " XBD=718 XHG=672 YBD=837 YHG=816>no " XBD=838 XHG=734 YBD=845 YHG=805>pubic " XBD=890 XHG=851 YBD=836 YHG=816>or " XBD=1036 XHG=900 YBD=844 YHG=805>axillary " XBD=1131 XHG=1049 YBD=843 YHG=806>hair, " XBD=1213 XHG=1145 YBD=836 YHG=806>and " XBD=1324 XHG=1227 YBD=837 YHG=806>small" XBD=209 XHG=140 YBD=883 YHG=851>soft " XBD=335 XHG=222 YBD=884 YHG=859>testes. " XBD=424 XHG=365 YBD=890 YHG=860>i.Q. " XBD=511 XHG=443 YBD=884 YHG=862>was " XBD=571 XHG=529 YBD=883 YHG=854>46 " XBD=624 XHG=588 YBD=883 YHG=853>in " XBD=699 XHG=641 YBD=886 YHG=853>the " XBD=787 XHG=715 YBD=883 YHG=853>first " XBD=897 XHG=804 YBD=888 YHG=852>twin, " XBD=981 XHG=914 YBD=883 YHG=853>and " XBD=1040 XHG=998 YBD=883 YHG=853>43 " XBD=1093 XHG=1057 YBD=883 YHG=852>in " XBD=1167 XHG=1109 YBD=883 YHG=853>the " XBD=1321 XHG=1185 YBD=884 YHG=853>second." XBD=230 XHG=139 YBD=930 YHG=898>Both " XBD=342 XHG=242 YBD=929 YHG=899>twins " XBD=424 XHG=356 YBD=929 YHG=898>had " XBD=569 XHG=442 YBD=930 YHG=898>double " XBD=850 XHG=586 YBD=930 YHG=898>sex-chromatin " XBD=980 XHG=864 YBD=929 YHG=898>bodies " XBD=1029 XHG=994 YBD=929 YHG=898>in " XBD=1164 XHG=1047 YBD=929 YHG=898>buccal " XBD=1323 XHG=1179 YBD=935 YHG=908>smears;" XBD=207 XHG=138 YBD=976 YHG=945>and " XBD=312 XHG=227 YBD=976 YHG=945>both " XBD=399 XHG=331 YBD=976 YHG=945>had " XBD=461 XHG=418 YBD=976 YHG=945>48 " XBD=746 XHG=482 YBD=980 YHG=945>chromosomes, " XBD=912 XHG=766 YBD=980 YHG=945>XXXY, " XBD=966 XHG=932 YBD=975 YHG=954>as " XBD=1131 XHG=986 YBD=976 YHG=944>follows:

" XBD=467 XHG=135 YBD=1240 YHG=1201>Testicular-biopsy " XBD=676 XHG=503 YBD=1240 YHG=1201>specimen " XBD=848 XHG=712 YBD=1232 YHG=1201>showed " XBD=1105 XHG=884 YBD=1239 YHG=1200>pronounced " XBD=1320 XHG=1138 YBD=1239 YHG=1200>hyalinisa-" XBD=208 XHG=134 YBD=1279 YHG=1248>tion " XBD=265 XHG=225 YBD=1278 YHG=1248>of " XBD=517 XHG=280 YBD=1279 YHG=1247>seminiferous " XBD=672 XHG=536 YBD=1278 YHG=1247>tubules " XBD=726 XHG=691 YBD=1277 YHG=1247>in " XBD=828 XHG=745 YBD=1278 YHG=1247>both " XBD=1003 XHG=845 YBD=1285 YHG=1247>patients, " XBD=1088 XHG=1021 YBD=1278 YHG=1247>and " XBD=1164 XHG=1106 YBD=1278 YHG=1247>the " XBD=1321 XHG=1182 YBD=1285 YHG=1247>urinary" XBD=411 XHG=136 YBD=1333 YHG=1294>gonadotrophin " XBD=598 XHG=427 YBD=1325 YHG=1294>excretion " XBD=679 XHG=613 YBD=1324 YHG=1303>was " XBD=801 XHG=695 YBD=1324 YHG=1293>above " XBD=857 XHG=815 YBD=1324 YHG=1294>48 " XBD=991 XHG=873 YBD=1325 YHG=1303>mouse " XBD=1137 XHG=1005 YBD=1324 YHG=1293>uterine " XBD=1244 XHG=1152 YBD=1324 YHG=1293>units " XBD=1321 XHG=1259 YBD=1332 YHG=1303>per" XBD=177 XHG=134 YBD=1371 YHG=1341>24 " XBD=318 XHG=213 YBD=1372 YHG=1340>hours " XBD=390 XHG=355 YBD=1371 YHG=1340>in " XBD=513 XHG=427 YBD=1371 YHG=1340>both " XBD=658 XHG=548 YBD=1371 YHG=1340>twins. " XBD=799 XHG=705 YBD=1371 YHG=1339>ABO " XBD=904 XHG=837 YBD=1371 YHG=1340>and " XBD=1020 XHG=942 YBD=1370 YHG=1340>MN " XBD=1320 XHG=1057 YBD=1379 YHG=1340>blood-groups," XBD=303 XHG=137 YBD=1418 YHG=1387>secretion " XBD=391 XHG=323 YBD=1417 YHG=1387>and " XBD=663 XHG=407 YBD=1418 YHG=1386>non-secretion " XBD=720 XHG=681 YBD=1417 YHG=1386>of " XBD=962 XHG=733 YBD=1425 YHG=1386>blood-group " XBD=1144 XHG=980 YBD=1424 YHG=1386>antigens, " XBD=1218 XHG=1163 YBD=1418 YHG=1396>ear " XBD=1320 XHG=1235 YBD=1423 YHG=1396>wax," XBD=343 XHG=135 YBD=1471 YHG=1433>mid-digital " XBD=458 XHG=373 YBD=1470 YHG=1433>hair, " XBD=574 XHG=489 YBD=1464 YHG=1440>taste " XBD=721 XHG=604 YBD=1470 YHG=1432>ability " XBD=786 XHG=750 YBD=1464 YHG=1439>to " XBD=1220 XHG=815 YBD=1471 YHG=1433>phenylthiocarbamide, " XBD=1320 XHG=1252 YBD=1464 YHG=1433>and" XBD=369 XHG=135 YBD=1519 YHG=1480>finger-prints " XBD=479 XHG=391 YBD=1511 YHG=1490>were " XBD=609 XHG=500 YBD=1510 YHG=1479>tested " XBD=684 XHG=630 YBD=1510 YHG=1478>for " XBD=855 XHG=705 YBD=1518 YHG=1479>zygosity " XBD=1055 XHG=876 YBD=1518 YHG=1479>diagnosis. " XBD=1193 XHG=1115 YBD=1511 YHG=1480>The " XBD=1319 XHG=1214 YBD=1518 YHG=1480>prob-" XBD=252 XHG=136 YBD=1565 YHG=1526>ability " XBD=309 XHG=269 YBD=1558 YHG=1526>of " XBD=380 XHG=322 YBD=1557 YHG=1526>the " XBD=471 XHG=396 YBD=1565 YHG=1527>pair " XBD=591 XHG=489 YBD=1565 YHG=1526>being " XBD=845 XHG=608 YBD=1564 YHG=1526>monozygotic " XBD=927 XHG=861 YBD=1557 YHG=1537>was |>" XBD=1066 XHG=946 YBD=1558 YHG=1527>0-9896 " XBD=1265 XHG=1084 YBD=1565 YHG=1527>according " XBD=1319 XHG=1283 YBD=1557 YHG=1534>to" XBD=295 XHG=137 YBD=1611 YHG=1573>Inouye’s " XBD=500 XHG=332 YBD=1604 YHG=1572>method. 2 " XBD=835 XHG=572 YBD=1611 YHG=1573>Monozygosity " XBD=910 XHG=871 YBD=1604 YHG=1573>of " XBD=999 XHG=942 YBD=1604 YHG=1573>the " XBD=1107 XHG=1035 YBD=1612 YHG=1573>pair " XBD=1210 XHG=1143 YBD=1605 YHG=1584>was " XBD=1319 XHG=1248 YBD=1604 YHG=1574>also" XBD=340 XHG=137 YBD=1651 YHG=1619>established " XBD=401 XHG=356 YBD=1658 YHG=1620>by " XBD=576 XHG=417 YBD=1650 YHG=1619>different " XBD=953 XHG=592 YBD=1658 YHG=1619>similarity-diagnosis " XBD=1137 XHG=970 YBD=1651 YHG=1620>methods." XBD=280 XHG=178 YBD=1701 YHG=1673>These " XBD=385 XHG=295 YBD=1701 YHG=1673>twins " XBD=462 XHG=400 YBD=1701 YHG=1672>will " XBD=517 XHG=478 YBD=1701 YHG=1673>be " XBD=677 XHG=532 YBD=1708 YHG=1673>reported " XBD=724 XHG=691 YBD=1701 YHG=1673>in " XBD=825 XHG=739 YBD=1702 YHG=1682>more " XBD=932 XHG=841 YBD=1702 YHG=1674>detail " XBD=1120 XHG=948 YBD=1702 YHG=1673>elsewhere.

HISAO TAKAYASU.Department of Urology,

KENJI KINOSHITATAKAYUKI TSUBOITETSURO KURIHARA.

Department of Human Geneticsand Criminology,

Institute of Brain Research,University of Tokyo, Tokyo.

MICROANGIOPATHIC HÆMOLYTIC ANÆMIA

|>" XBD=340 XHG=179 YBD=2207 YHG=2170>SIR,-In " XBD=447 XHG=360 YBD=2201 YHG=2170>their " XBD=665 XHG=468 YBD=2208 YHG=2169>interesting " XBD=902 XHG=685 YBD=2208 YHG=2169>preliminary " XBD=1224 XHG=923 YBD=2206 YHG=2169>communication, " XBD=1310 XHG=1246 YBD=2200 YHG=2170>Dr." XBD=339 XHG=132 YBD=2254 YHG=2216>Rubenberg " XBD=425 XHG=358 YBD=2247 YHG=2216>and " XBD=495 XHG=443 YBD=2247 YHG=2217>his " XBD=701 XHG=516 YBD=2254 YHG=2216>colleagues " XBD=825 XHG=722 YBD=2255 YHG=2216>(Nov. " XBD=900 XHG=847 YBD=2253 YHG=2217>25, " XBD=953 XHG=920 YBD=2255 YHG=2225>p. " XBD=1075 XHG=978 YBD=2254 YHG=2216>1121) " XBD=1211 XHG=1096 YBD=2254 YHG=2223>report " XBD=1310 XHG=1230 YBD=2254 YHG=2225>pro-" XBD=254 XHG=131 YBD=2302 YHG=2263>longed " XBD=462 XHG=271 YBD=2302 YHG=2263>hxmolysis " XBD=563 XHG=481 YBD=2294 YHG=2264>with " XBD=719 XHG=580 YBD=2294 YHG=2263>red-cell " XBD=997 XHG=737 YBD=2301 YHG=2263>fragmentation " XBD=1188 XHG=1014 YBD=2301 YHG=2262>following " XBD=1310 XHG=1205 YBD=2300 YHG=2262>injec-" XBD=203 XHG=130 YBD=2341 YHG=2309>tion " XBD=259 XHG=220 YBD=2341 YHG=2310>of " XBD=291 XHG=273 YBD=2340 YHG=2320>a " XBD=486 XHG=309 YBD=2348 YHG=2310>coagulant " XBD=646 XHG=504 YBD=2341 YHG=2309>fraction " XBD=704 XHG=664 YBD=2341 YHG=2310>of " XBD=774 XHG=717 YBD=2341 YHG=2310>the " XBD=915 XHG=792 YBD=2341 YHG=2319>venom " XBD=973 XHG=933 YBD=2340 YHG=2310>of " XBD=1044 XHG=986 YBD=2340 YHG=2309>the " XBD=1223 XHG=1062 YBD=2348 YHG=2310>Malayan " XBD=1309 XHG=1241 YBD=2347 YHG=2309>pit-" XBD=234 XHG=129 YBD=2395 YHG=2356>viper, " XBD=464 XHG=246 YBD=2395 YHG=2356>Agkistrodon " XBD=688 XHG=476 YBD=2393 YHG=2357>rhodostoma, " XBD=773 XHG=701 YBD=2388 YHG=2357>into " XBD=912 XHG=785 YBD=2387 YHG=2357>rabbits " XBD=960 XHG=925 YBD=2387 YHG=2356>in " XBD=1084 XHG=972 YBD=2387 YHG=2356>which " XBD=1154 XHG=1096 YBD=2387 YHG=2357>the " XBD=1308 XHG=1166 YBD=2387 YHG=2356>fibrino-" XBD=208 XHG=128 YBD=2441 YHG=2402>lytic " XBD=353 XHG=228 YBD=2441 YHG=2410>system " XBD=440 XHG=372 YBD=2435 YHG=2403>had " XBD=545 XHG=459 YBD=2434 YHG=2404>been " XBD=743 XHG=565 YBD=2434 YHG=2403>inhibited. " XBD=877 XHG=778 YBD=2441 YHG=2403>They " XBD=1031 XHG=896 YBD=2441 YHG=2410>suggest " XBD=1123 XHG=1050 YBD=2434 YHG=2403>that " XBD=1161 XHG=1143 YBD=2433 YHG=2413>a " XBD=1309 XHG=1182 YBD=2433 YHG=2403>similar" XBD=261 XHG=127 YBD=2488 YHG=2458>process " XBD=363 XHG=284 YBD=2488 YHG=2459>may " XBD=486 XHG=384 YBD=2480 YHG=2459>occur " XBD=542 XHG=507 YBD=2480 YHG=2449>in " XBD=692 XHG=563 YBD=2480 YHG=2450>human " XBD=857 XHG=713 YBD=2487 YHG=2449>patients " XBD=962 XHG=881 YBD=2480 YHG=2449>with " XBD=1308 XHG=983 YBD=2487 YHG=2449>microangiopathic" XBD=276 XHG=127 YBD=2527 YHG=2496>anaemia. " XBD=508 XHG=319 YBD=2534 YHG=2495>Klibansky " XBD=566 XHG=534 YBD=2527 YHG=2503>et " XBD=649 XHG=592 YBD=2527 YHG=2496>awl. " XBD=760 XHG=675 YBD=2527 YHG=2496>have " XBD=855 XHG=786 YBD=2527 YHG=2496>also " XBD=1040 XHG=882 YBD=2534 YHG=2496>reported " XBD=1307 XHG=1066 YBD=2527 YHG=2496>intravascular|>" XBD=317 XHG=126 YBD=2581 YHG=2542>haemolysis " XBD=442 XHG=359 YBD=2573 YHG=2542>with " XBD=621 XHG=482 YBD=2574 YHG=2543>red-cell " XBD=834 XHG=663 YBD=2574 YHG=2543>crenation " XBD=1048 XHG=875 YBD=2581 YHG=2543>following " XBD=1306 XHG=1088 YBD=2574 YHG=2542>intravenous" XBD=396 XHG=126 YBD=2620 YHG=2589>administration " XBD=461 XHG=421 YBD=2619 YHG=2589>of " XBD=576 XHG=482 YBD=2620 YHG=2589>Echis " XBD=757 XHG=600 YBD=2620 YHG=2589>coloratus " XBD=904 XHG=781 YBD=2620 YHG=2599>venom " XBD=965 XHG=930 YBD=2620 YHG=2589>in " XBD=1083 XHG=990 YBD=2627 YHG=2589>dogs. " XBD=1224 XHG=1124 YBD=2627 YHG=2589>They " XBD=1306 XHG=1248 YBD=2620 YHG=2596>too" XBD=278 XHG=125 YBD=2667 YHG=2636>ascribed " XBD=354 XHG=295 YBD=2667 YHG=2636>the " XBD=611 XHG=373 YBD=2666 YHG=2635>intravascular |>" XBD=819 XHG=628 YBD=2673 YHG=2636>hxmolysis " XBD=875 XHG=839 YBD=2665 YHG=2642>to " XBD=1034 XHG=894 YBD=2673 YHG=2635>damage " XBD=1087 XHG=1052 YBD=2666 YHG=2643>to " XBD=1306 XHG=1107 YBD=2673 YHG=2636>circulating" XBD=183 XHG=124 YBD=2714 YHG=2682>red " XBD=275 XHG=198 YBD=2714 YHG=2682>cells " XBD=475 XHG=290 YBD=2714 YHG=2681>enmeshed " XBD=523 XHG=489 YBD=2712 YHG=2682>in " XBD=631 XHG=536 YBD=2713 YHG=2682>small " XBD=745 XHG=644 YBD=2713 YHG=2682>fibrin " XBD=854 XHG=759 YBD=2718 YHG=2682>clots, " XBD=929 XHG=868 YBD=2712 YHG=2682>but " XBD=1022 XHG=943 YBD=2721 YHG=2682>they " XBD=1235 XHG=1036 YBD=2713 YHG=2682>considered " XBD=1306 XHG=1247 YBD=2714 YHG=2682>the" XBD=363 XHG=124 YBD=2760 YHG=2729>intravascular " XBD=575 XHG=384 YBD=2766 YHG=2728>haemolysis " XBD=632 XHG=597 YBD=2759 YHG=2735>to " XBD=696 XHG=654 YBD=2760 YHG=2730>be " XBD=757 XHG=717 YBD=2759 YHG=2729>of " XBD=886 XHG=774 YBD=2759 YHG=2729>minor " XBD=945 XHG=907 YBD=2759 YHG=2739>or " XBD=1011 XHG=965 YBD=2759 YHG=2739>no " XBD=1248 XHG=1033 YBD=2767 YHG=2729>significance " XBD=1305 XHG=1269 YBD=2759 YHG=2729>in" XBD=180 XHG=123 YBD=2806 YHG=2776>the " XBD=414 XHG=209 YBD=2814 YHG=2775>production " XBD=483 XHG=443 YBD=2805 YHG=2775>of |>" XBD=657 XHG=508 YBD=2806 YHG=2775>anxmia. " XBD=786 XHG=701 YBD=2806 YHG=2775>This " XBD=956 XHG=816 YBD=2813 YHG=2775>opinion " XBD=1011 XHG=985 YBD=2806 YHG=2775>is " XBD=1230 XHG=1042 YBD=2813 YHG=2775>supported " XBD=1306 XHG=1259 YBD=2813 YHG=2776>by" XBD=354 XHG=123 YBD=2853 YHG=2822>observations " XBD=417 XHG=378 YBD=2852 YHG=2822>of " XBD=565 XHG=436 YBD=2852 YHG=2821>human " XBD=732 XHG=588 YBD=2860 YHG=2822>patients " XBD=832 XHG=756 YBD=2852 YHG=2822>who " XBD=923 XHG=855 YBD=2852 YHG=2821>had " XBD=1033 XHG=947 YBD=2853 YHG=2822>been " XBD=1166 XHG=1057 YBD=2853 YHG=2822>bitten " XBD=1235 XHG=1191 YBD=2860 YHG=2823>by " XBD=1302 XHG=1258 YBD=2852 YHG=2822>A." XBD=324 XHG=123 YBD=2900 YHG=2868>rhodostoma " XBD=415 XHG=348 YBD=2899 YHG=2868>and " XBD=516 XHG=438 YBD=2898 YHG=2868>who " XBD=605 XHG=538 YBD=2899 YHG=2868>had " XBD=785 XHG=628 YBD=2906 YHG=2868>systemic " XBD=987 XHG=807 YBD=2906 YHG=2868>poisoning " XBD=1092 XHG=1010 YBD=2899 YHG=2868>with " XBD=1304 XHG=1115 YBD=2906 YHG=2868>prolonged" XBD=389 XHG=123 YBD=2946 YHG=2915>defibrination.4 " XBD=575 XHG=420 YBD=2945 YHG=2915>Anaemia " XBD=702 XHG=594 YBD=2952 YHG=2915>might " XBD=864 XHG=722 YBD=2953 YHG=2915>develop " XBD=947 XHG=885 YBD=2945 YHG=2915>but " XBD=1060 XHG=966 YBD=2946 YHG=2915>there " XBD=1146 XHG=1080 YBD=2946 YHG=2925>was " XBD=1213 XHG=1167 YBD=2946 YHG=2925>no " XBD=1303 XHG=1234 YBD=2945 YHG=2915>evi-" XBD=229 XHG=123 YBD=2992 YHG=2962>dence " XBD=290 XHG=251 YBD=2992 YHG=2962>of " XBD=485 XHG=309 YBD=2992 YHG=2961>abnormal " XBD=708 XHG=507 YBD=2999 YHG=2961>haemolysis. " XBD=916 XHG=743 YBD=2999 YHG=2961>Repeated " XBD=1019 XHG=938 YBD=2992 YHG=2968>tests " XBD=1102 XHG=1043 YBD=2992 YHG=2961>did " XBD=1186 XHG=1124 YBD=2992 YHG=2969>not " XBD=1304 XHG=1208 YBD=2992 YHG=2961>show" XBD=188 XHG=123 YBD=3045 YHG=3017>any " XBD=357 XHG=209 YBD=3039 YHG=3008>increase " XBD=414 XHG=378 YBD=3037 YHG=3007>in " XBD=821 XHG=435 YBD=3045 YHG=3007>plasma-haemoglobin, " XBD=1088 XHG=843 YBD=3045 YHG=3007>reticulocytes, " XBD=1149 XHG=1111 YBD=3038 YHG=3017>or " XBD=1302 XHG=1171 YBD=3039 YHG=3017>serum-" XBD=295 XHG=123 YBD=3085 YHG=3054>bilirubin. " XBD=410 XHG=334 YBD=3084 YHG=3054>The " XBD=602 XHG=436 YBD=3084 YHG=3053>Schumm " XBD=688 XHG=624 YBD=3084 YHG=3060>test " XBD=777 XHG=712 YBD=3084 YHG=3063>was " XBD=986 XHG=802 YBD=3091 YHG=3053>invariably " XBD=1172 XHG=1008 YBD=3092 YHG=3054>negative. " XBD=1302 XHG=1209 YBD=3084 YHG=3053>Red-" XBD=184 XHG=123 YBD=3130 YHG=3100>cell " XBD=432 XHG=207 YBD=3138 YHG=3100>morphology " XBD=620 XHG=453 YBD=3138 YHG=3099>appeared " XBD=771 XHG=641 YBD=3130 YHG=3100>normal " XBD=829 XHG=794 YBD=3130 YHG=3100>in " XBD=1061 XHG=851 YBD=3130 YHG=3100>blood-films " XBD=1262 XHG=1084 YBD=3138 YHG=3100>(although " XBD=1303 XHG=1284 YBD=3129 YHG=3109>a" XBD=259 XHG=123 YBD=3183 YHG=3146>specific " XBD=387 XHG=271 YBD=3177 YHG=3146>search " XBD=466 XHG=399 YBD=3177 YHG=3156>was " XBD=538 XHG=478 YBD=3177 YHG=3153>not " XBD=648 XHG=550 YBD=3177 YHG=3146>made " XBD=713 XHG=660 YBD=3176 YHG=3146>for " XBD=864 XHG=724 YBD=3176 YHG=3145>red-cell " XBD=1161 XHG=876 YBD=3184 YHG=3146>fragmentation). " XBD=1303 XHG=1189 YBD=3176 YHG=3146>There" XBD=189 XHG=122 YBD=3222 YHG=3200>was " XBD=252 XHG=206 YBD=3222 YHG=3201>no " XBD=583 XHG=268 YBD=3230 YHG=3192>haemoglobinuria, " XBD=666 XHG=600 YBD=3223 YHG=3192>and " XBD=728 XHG=683 YBD=3223 YHG=3202>no " XBD=892 XHG=744 YBD=3223 YHG=3191>increase " XBD=945 XHG=909 YBD=3223 YHG=3193>in " XBD=1098 XHG=961 YBD=3230 YHG=3192>urinary " XBD=1302 XHG=1114 YBD=3223 YHG=3192>urobilino-" XBD=197 XHG=123 YBD=3276 YHG=3246>gen. " XBD=272 XHG=232 YBD=3268 YHG=3238>In " XBD=349 XHG=290 YBD=3269 YHG=3238>the " XBD=528 XHG=367 YBD=3276 YHG=3238>minority " XBD=622 XHG=546 YBD=3269 YHG=3239>who " XBD=698 XHG=641 YBD=3276 YHG=3245>got " XBD=904 XHG=717 YBD=3276 YHG=3237>significant |>" XBD=1075 XHG=923 YBD=3275 YHG=3238>anaemia, " XBD=1214 XHG=1094 YBD=3269 YHG=3238>visible " XBD=1301 XHG=1232 YBD=3268 YHG=3238>dis-" XBD=307 XHG=122 YBD=3315 YHG=3284>coloration " XBD=506 XHG=326 YBD=3322 YHG=3285>suggested " XBD=595 XHG=523 YBD=3315 YHG=3285>that " XBD=679 XHG=612 YBD=3315 YHG=3285>loss " XBD=736 XHG=697 YBD=3316 YHG=3284>of " XBD=809 XHG=749 YBD=3315 YHG=3285>red " XBD=905 XHG=827 YBD=3315 YHG=3285>cells " XBD=996 XHG=924 YBD=3315 YHG=3285>into " XBD=1071 XHG=1013 YBD=3315 YHG=3285>the " XBD=1199 XHG=1089 YBD=3315 YHG=3285>bitten " XBD=1301 XHG=1217 YBD=3314 YHG=3284>limb" XBD=188 XHG=122 YBD=3361 YHG=3340>was " XBD=266 XHG=209 YBD=3361 YHG=3330>the " XBD=396 XHG=286 YBD=3361 YHG=3331>causal " XBD=635 XHG=417 YBD=3361 YHG=3331>mechanism. " XBD=816 XHG=670 YBD=3361 YHG=3330>Patients " XBD=913 XHG=836 YBD=3361 YHG=3331>who " XBD=1020 XHG=933 YBD=3361 YHG=3341>were " XBD=1138 XHG=1041 YBD=3361 YHG=3331>siven " XBD=1216 XHG=1158 YBD=3361 YHG=3331>the " XBD=1301 XHG=1236 YBD=3360 YHG=3330>fib-

1. Holub, D. A., Grumbach, M. M., Tailer, J. W. J. clin. Endocr. Metab.1958, 18, 1359. Frøland, A., Johnson, S. G., Andresen, P., Dein, E.,Sanger, R., Race, R. R. Lancet, 1963, ii, 1121. Nowakowski, H.,Lenz, W., Bergman, S., Reitalu, J. Path. Biol., Paris, 1963, 11, 1239.

2. Inouye, E. Studies on Twins. III. Japanese Society for Promotion ofScience, 1963 (in Japanese).

3. Klibansky, Ch., Ozcan, E., Joshua, H., Dialdetti, M., Bessler, H.,de Vries, A. Toxicon, 1966, 3, 213.

4. Reid, H. A., Thean, P. C., Chan, K. E., Baharom, A. R. Lancet, 1963,i, 617.

" XBD=1551 XHG=1394 YBD=356 YHG=318>rinolytic " XBD=1738 XHG=1576 YBD=349 YHG=318>inhibitor " XBD=2044 XHG=1766 YBD=356 YHG=318>e-aminocaproic " XBD=2143 XHG=2070 YBD=349 YHG=318>acid " XBD=2325 XHG=2170 YBD=356 YHG=318>(E.A.C.A.) " XBD=2467 XHG=2352 YBD=355 YHG=317>during " XBD=2542 XHG=2492 YBD=350 YHG=318>the" XBD=1621 XHG=1393 YBD=402 YHG=364>non-clotting " XBD=1744 XHG=1641 YBD=402 YHG=364>phase " XBD=1803 XHG=1764 YBD=395 YHG=365>of defibrination " XBD=2166 XHG=2069 YBD=394 YHG=364>5 had " XBD=2407 XHG=2186 YBD=395 YHG=363>whole-blood " XBD=2540 XHG=2426 YBD=395 YHG=364>haemo-" XBD=1509 XHG=1393 YBD=448 YHG=410>globin " XBD=1634 XHG=1535 YBD=441 YHG=410>levels " XBD=1727 XHG=1661 YBD=440 YHG=410>and " XBD=1958 XHG=1752 YBD=448 YHG=410>packed-cell " XBD=2133 XHG=1984 YBD=441 YHG=410>volumes " XBD=2267 XHG=2160 YBD=441 YHG=410>which " XBD=2349 XHG=2292 YBD=440 YHG=410>did " XBD=2430 XHG=2373 YBD=440 YHG=416>not " XBD=2540 XHG=2453 YBD=441 YHG=410>differ" XBD=1616 XHG=1393 YBD=494 YHG=456>significantly " XBD=1721 XHG=1632 YBD=486 YHG=456>from " XBD=1834 XHG=1739 YBD=487 YHG=456>those " XBD=1887 XHG=1851 YBD=486 YHG=456>in " XBD=2046 XHG=1904 YBD=494 YHG=456>patients " XBD=2123 XHG=2063 YBD=487 YHG=463>not " XBD=2236 XHG=2140 YBD=493 YHG=456>given " XBD=2378 XHG=2252 YBD=487 YHG=463>E.A.C.A. " XBD=2424 XHG=2410 YBD=485 YHG=455>I " XBD=2538 XHG=2441 YBD=486 YHG=455>there-" XBD=1465 XHG=1392 YBD=533 YHG=502>fore " XBD=1598 XHG=1490 YBD=533 YHG=502>doubt " XBD=1772 XHG=1622 YBD=533 YHG=502>whether " XBD=1852 XHG=1796 YBD=533 YHG=503>the " XBD=2099 XHG=1878 YBD=540 YHG=503>experiments " XBD=2162 XHG=2124 YBD=533 YHG=502>of " XBD=2241 XHG=2181 YBD=533 YHG=502>Dr. " XBD=2459 XHG=2263 YBD=539 YHG=502>Rubenberg " XBD=2538 XHG=2481 YBD=533 YHG=503>and" XBD=1444 XHG=1390 YBD=580 YHG=549>his " XBD=1647 XHG=1462 YBD=587 YHG=549>colleagues " XBD=1796 XHG=1665 YBD=587 YHG=549>explain " XBD=1869 XHG=1813 YBD=579 YHG=549>the " XBD=2088 XHG=1886 YBD=587 YHG=549>production " XBD=2143 XHG=2104 YBD=579 YHG=549>of " XBD=2293 XHG=2156 YBD=579 YHG=548>anamia " XBD=2344 XHG=2309 YBD=579 YHG=549>in " XBD=2414 XHG=2359 YBD=579 YHG=548>the " XBD=2537 XHG=2429 YBD=580 YHG=548>micro-" XBD=1605 XHG=1391 YBD=633 YHG=595>angiopathic " XBD=1811 XHG=1620 YBD=633 YHG=595>hasmolytic " XBD=2007 XHG=1827 YBD=633 YHG=596>syndrome " XBD=2057 XHG=2023 YBD=624 YHG=594>in " XBD=2160 XHG=2072 YBD=626 YHG=605>man.

H. A. REID.School of Tropical Medicine,

Liverpool 3.

ANTIBODIES TO GASTRIN

|>" XBD=1614 XHG=1435 YBD=909 YHG=872>SIR,-Dr. " XBD=1807 XHG=1641 YBD=910 YHG=872>Stremple " XBD=1896 XHG=1830 YBD=902 YHG=872>and " XBD=1970 XHG=1918 YBD=902 YHG=872>his " XBD=2193 XHG=1994 YBD=902 YHG=872>co-workers " XBD=2312 XHG=2216 YBD=909 YHG=871>(Dec. " XBD=2369 XHG=2339 YBD=906 YHG=872>2, " XBD=2423 XHG=2392 YBD=908 YHG=880>p. " XBD=2531 XHG=2449 YBD=911 YHG=872>1180)" XBD=1497 XHG=1387 YBD=949 YHG=918>write: " XBD=1533 XHG=1513 YBD=931 YHG=918>&dquo; " XBD=1603 XHG=1547 YBD=948 YHG=918>the " XBD=1736 XHG=1616 YBD=955 YHG=918>gastric " XBD=1822 XHG=1749 YBD=948 YHG=918>acid " XBD=2044 XHG=1836 YBD=955 YHG=918>stimulatory " XBD=2190 XHG=2056 YBD=955 YHG=918>portion " XBD=2244 XHG=2206 YBD=948 YHG=917>of " XBD=2322 XHG=2257 YBD=948 YHG=917>this " XBD=2531 XHG=2338 YBD=955 YHG=917>polypeptide" XBD=1569 XHG=1390 YBD=1002 YHG=964>[synthetic " XBD=1717 XHG=1589 YBD=995 YHG=964>human " XBD=1862 XHG=1738 YBD=1002 YHG=964>gastrin " XBD=1908 XHG=1884 YBD=1002 YHG=964>I] " XBD=1958 XHG=1932 YBD=994 YHG=964>is " XBD=2143 XHG=1980 YBD=1002 YHG=964>probably " XBD=2316 XHG=2163 YBD=995 YHG=963>identical " XBD=2369 XHG=2336 YBD=993 YHG=970>to " XBD=2440 XHG=2389 YBD=994 YHG=963>the " XBD=2529 XHG=2458 YBD=995 YHG=965>anti-" XBD=1483 XHG=1387 YBD=1049 YHG=1011>genic " XBD=1725 XHG=1501 YBD=1041 YHG=1010>determinant " XBD=1771 XHG=1740 YBD=1042 YHG=1011>&dquo;. " XBD=1878 XHG=1803 YBD=1041 YHG=1011>The " XBD=2052 XHG=1897 YBD=1048 YHG=1011>&dquo; gastric " XBD=2142 XHG=2068 YBD=1041 YHG=1010>acid " XBD=2365 XHG=2159 YBD=1047 YHG=1010>stimulatory " XBD=2499 XHG=2379 YBD=1048 YHG=1010>portion " XBD=2528 XHG=2512 YBD=1025 YHG=1012>&dquo;" XBD=1602 XHG=1386 YBD=1095 YHG=1057>presumably " XBD=1732 XHG=1630 YBD=1087 YHG=1057>refers " XBD=1796 XHG=1760 YBD=1087 YHG=1064>to " XBD=1880 XHG=1823 YBD=1087 YHG=1057>the " XBD=2108 XHG=1909 YBD=1087 YHG=1056>C-terminal " XBD=2353 XHG=2136 YBD=1095 YHG=1056>tetrapeptide " XBD=2478 XHG=2379 YBD=1088 YHG=1056>amide " XBD=2532 XHG=2501 YBD=1088 YHG=1059>of" XBD=1521 XHG=1385 YBD=1141 YHG=1103>gastrin. " XBD=1646 XHG=1547 YBD=1134 YHG=1102>Since " XBD=1750 XHG=1655 YBD=1133 YHG=1103>Mutt " XBD=1826 XHG=1760 YBD=1133 YHG=1103>and " XBD=1951 XHG=1835 YBD=1141 YHG=1103>Jorpes " XBD=1978 XHG=1966 YBD=1120 YHG=1103>6 " XBD=2073 XHG=1990 YBD=1133 YHG=1103>have " XBD=2200 XHG=2084 YBD=1133 YHG=1103>shown " XBD=2279 XHG=2208 YBD=1133 YHG=1103>that " XBD=2344 XHG=2288 YBD=1134 YHG=1103>the " XBD=2528 XHG=2353 YBD=1134 YHG=1102>C-terminal" XBD=1610 XHG=1386 YBD=1187 YHG=1149>tetrapeptide " XBD=1743 XHG=1632 YBD=1179 YHG=1149>amide " XBD=1805 XHG=1766 YBD=1179 YHG=1149>of " XBD=2376 XHG=1824 YBD=1187 YHG=1148>cholecystokinin-pancreozymin " XBD=2422 XHG=2397 YBD=1179 YHG=1148>is " XBD=2527 XHG=2441 YBD=1188 YHG=1150>prob-" XBD=1464 XHG=1386 YBD=1233 YHG=1195>ably " XBD=1635 XHG=1479 YBD=1227 YHG=1195>identical " XBD=1686 XHG=1651 YBD=1226 YHG=1202>to " XBD=1774 XHG=1702 YBD=1226 YHG=1195>that " XBD=1828 XHG=1789 YBD=1226 YHG=1196>of " XBD=1976 XHG=1839 YBD=1234 YHG=1196>gastrin, " XBD=2178 XHG=1992 YBD=1227 YHG=1195>antibodies " XBD=2228 XHG=2194 YBD=1226 YHG=1203>to " XBD=2366 XHG=2244 YBD=1233 YHG=1195>gastrin " XBD=2481 XHG=2381 YBD=1227 YHG=1196>would " XBD=2527 XHG=2494 YBD=1228 YHG=1197>be" XBD=1548 XHG=1386 YBD=1280 YHG=1241>expected " XBD=1604 XHG=1570 YBD=1272 YHG=1249>to " XBD=1825 XHG=1627 YBD=1273 YHG=1248>cross-react " XBD=1927 XHG=1845 YBD=1273 YHG=1242>with " XBD=2492 XHG=1944 YBD=1280 YHG=1242>cholecystokinin-pancreozymin, " XBD=2530 XHG=2507 YBD=1274 YHG=1243>if" XBD=1443 XHG=1385 YBD=1319 YHG=1287>the " XBD=1672 XHG=1460 YBD=1326 YHG=1289>assumption " XBD=1728 XHG=1688 YBD=1319 YHG=1289>of " XBD=1803 XHG=1741 YBD=1319 YHG=1289>Dr. " XBD=1991 XHG=1825 YBD=1327 YHG=1288>Stremple " XBD=2073 XHG=2008 YBD=1320 YHG=1289>and " XBD=2142 XHG=2090 YBD=1320 YHG=1289>his " XBD=2357 XHG=2160 YBD=1320 YHG=1289>co-workers " XBD=2466 XHG=2374 YBD=1320 YHG=1289>about " XBD=2526 XHG=2480 YBD=1321 YHG=1290>the" XBD=1553 XHG=1385 YBD=1372 YHG=1335>antigenic " XBD=1793 XHG=1569 YBD=1366 YHG=1335>determinant " XBD=1835 XHG=1808 YBD=1366 YHG=1335>is " XBD=1988 XHG=1852 YBD=1366 YHG=1342>correct.

MORTON I. GROSSMAN.Veterans Administration Center,

Los Angles, California 90073.

Obituary

" XBD=1842 XHG=1675 YBD=1727 YHG=1697>HENRY " XBD=2008 XHG=1866 YBD=1727 YHG=1696>CECIL " XBD=2260 XHG=2028 YBD=1735 YHG=1696>JENNINGS" XBD=1712 XHG=1611 YBD=1786 YHG=1753>M.A., " XBD=1814 XHG=1729 YBD=1781 YHG=1753>M.B. " XBD=1944 XHG=1832 YBD=1786 YHG=1753>Lond., " XBD=2049 XHG=1962 YBD=1781 YHG=1753>B.Sc. " XBD=2180 XHG=2067 YBD=1787 YHG=1753>Oxon., " XBD=2315 XHG=2196 YBD=1781 YHG=1753>D.P.H.

" XBD=1498 XHG=1431 YBD=1846 YHG=1812>Dr. " XBD=1577 XHG=1527 YBD=1846 YHG=1812>H. " XBD=1649 XHG=1605 YBD=1846 YHG=1812>C. " XBD=1865 XHG=1677 YBD=1854 YHG=1812>Jennings, " XBD=2063 XHG=1892 YBD=1854 YHG=1812>formerly " XBD=2224 XHG=2089 YBD=1854 YHG=1819>county " XBD=2397 XHG=2248 YBD=1846 YHG=1812>medical " XBD=2526 XHG=2421 YBD=1847 YHG=1813>officer" XBD=1439 XHG=1381 YBD=1898 YHG=1864>for " XBD=1725 XHG=1471 YBD=1905 YHG=1864>Oxfordshire, " XBD=1842 XHG=1757 YBD=1897 YHG=1864>died " XBD=1908 XHG=1873 YBD=1898 YHG=1871>at " XBD=1994 XHG=1938 YBD=1898 YHG=1864>his " XBD=2135 XHG=2025 YBD=1898 YHG=1864>home " XBD=2200 XHG=2165 YBD=1898 YHG=1872>at " XBD=2458 XHG=2230 YBD=1905 YHG=1865>Eastbourne, " XBD=2526 XHG=2485 YBD=1899 YHG=1876>on" XBD=1479 XHG=1381 YBD=1951 YHG=1916>Nov. " XBD=1545 XHG=1503 YBD=1949 YHG=1917>19 " XBD=1600 XHG=1565 YBD=1949 YHG=1923>at " XBD=1682 XHG=1619 YBD=1950 YHG=1916>the " XBD=1766 XHG=1701 YBD=1958 YHG=1926>age " XBD=1827 XHG=1785 YBD=1949 YHG=1917>of " XBD=1898 XHG=1842 YBD=1950 YHG=1917>74." XBD=1479 XHG=1425 YBD=2009 YHG=1978>He " XBD=1664 XHG=1512 YBD=2009 YHG=1978>received " XBD=1750 XHG=1697 YBD=2008 YHG=1978>his " XBD=1924 XHG=1784 YBD=2009 YHG=1977>medical " XBD=2135 XHG=1958 YBD=2009 YHG=1978>education " XBD=2200 XHG=2168 YBD=2009 YHG=1985>at " XBD=2362 XHG=2233 YBD=2009 YHG=1978>Oxford " XBD=2453 XHG=2392 YBD=2009 YHG=1978>and " XBD=2524 XHG=2484 YBD=2010 YHG=1979>St." XBD=1561 XHG=1379 YBD=2056 YHG=2025>Thomas’s " XBD=1755 XHG=1585 YBD=2063 YHG=2024>Hospital, " XBD=1887 XHG=1776 YBD=2056 YHG=2025>where " XBD=1948 XHG=1906 YBD=2056 YHG=2025>he " XBD=2128 XHG=1970 YBD=2063 YHG=2025>qualified " XBD=2183 XHG=2149 YBD=2055 YHG=2025>in " XBD=2298 XHG=2206 YBD=2056 YHG=2026>1915. " XBD=2459 XHG=2335 YBD=2064 YHG=2025>During " XBD=2526 XHG=2477 YBD=2057 YHG=2025>the" XBD=1525 XHG=1381 YBD=2103 YHG=2072>1914-18 " XBD=1618 XHG=1552 YBD=2102 YHG=2081>war " XBD=1687 XHG=1644 YBD=2102 YHG=2071>he " XBD=1830 XHG=1713 YBD=2103 YHG=2071>served " XBD=1891 XHG=1856 YBD=2102 YHG=2072>in " XBD=1973 XHG=1916 YBD=2103 YHG=2072>the " XBD=2103 XHG=1998 YBD=2110 YHG=2072>Royal " XBD=2237 XHG=2129 YBD=2110 YHG=2072>Navy, " XBD=2328 XHG=2263 YBD=2103 YHG=2072>and " XBD=2524 XHG=2353 YBD=2104 YHG=2072>afterwards" XBD=1521 XHG=1378 YBD=2149 YHG=2118>decided " XBD=1577 XHG=1542 YBD=2149 YHG=2125>to " XBD=1672 XHG=1597 YBD=2149 YHG=2118>take " XBD=1739 XHG=1693 YBD=2156 YHG=2128>up " XBD=1779 XHG=1761 YBD=2149 YHG=2128>a " XBD=1910 XHG=1801 YBD=2149 YHG=2128>career " XBD=1966 XHG=1930 YBD=2148 YHG=2119>in " XBD=2230 XHG=1985 YBD=2157 YHG=2118>public-health " XBD=2350 XHG=2250 YBD=2155 YHG=2119>work, " XBD=2525 XHG=2371 YBD=2157 YHG=2119>obtaining" XBD=1435 XHG=1376 YBD=2195 YHG=2164>the " XBD=1558 XHG=1451 YBD=2195 YHG=2172>D.P.H. " XBD=1612 XHG=1578 YBD=2194 YHG=2165>in " XBD=1725 XHG=1632 YBD=2195 YHG=2165>1920. " XBD=1853 XHG=1756 YBD=2196 YHG=2165>After " XBD=1994 XHG=1871 YBD=2196 YHG=2165>service " XBD=2092 XHG=2011 YBD=2195 YHG=2165>with " XBD=2165 XHG=2108 YBD=2196 YHG=2165>the " XBD=2289 XHG=2182 YBD=2196 YHG=2165>Leeds " XBD=2383 XHG=2307 YBD=2203 YHG=2165>City " XBD=2524 XHG=2399 YBD=2196 YHG=2165>Council" XBD=1420 XHG=1376 YBD=2242 YHG=2211>he " XBD=1501 XHG=1435 YBD=2242 YHG=2221>was " XBD=1701 XHG=1517 YBD=2250 YHG=2211>appointed " XBD=1842 XHG=1717 YBD=2250 YHG=2219>county " XBD=1998 XHG=1857 YBD=2242 YHG=2211>medical " XBD=2126 XHG=2014 YBD=2243 YHG=2212>officer " XBD=2193 XHG=2141 YBD=2243 YHG=2212>for " XBD=2364 XHG=2208 YBD=2249 YHG=2212>Holland, " XBD=2441 XHG=2379 YBD=2242 YHG=2211>and " XBD=2523 XHG=2455 YBD=2243 YHG=2211>then" XBD=1466 XHG=1375 YBD=2289 YHG=2265>went " XBD=1528 XHG=1482 YBD=2289 YHG=2268>on " XBD=1580 XHG=1545 YBD=2289 YHG=2265>to " XBD=1672 XHG=1597 YBD=2289 YHG=2258>take " XBD=1736 XHG=1689 YBD=2297 YHG=2268>up " XBD=1806 XHG=1753 YBD=2290 YHG=2258>his " XBD=2057 XHG=1824 YBD=2297 YHG=2258>appointment " XBD=2109 XHG=2074 YBD=2289 YHG=2258>in " XBD=2355 XHG=2127 YBD=2295 YHG=2258>Oxfordshire, " XBD=2474 XHG=2372 YBD=2289 YHG=2258>which " XBD=2523 XHG=2488 YBD=2289 YHG=2258>he" XBD=1455 XHG=1374 YBD=2336 YHG=2305>held " XBD=1533 XHG=1479 YBD=2336 YHG=2305>for " XBD=1596 XHG=1557 YBD=2335 YHG=2306>21 " XBD=1728 XHG=1623 YBD=2343 YHG=2315>years. " XBD=1809 XHG=1768 YBD=2336 YHG=2306>In " XBD=1918 XHG=1836 YBD=2336 YHG=2306>1935 " XBD=1986 XHG=1943 YBD=2336 YHG=2306>he " XBD=2088 XHG=2010 YBD=2336 YHG=2305>took " XBD=2168 XHG=2112 YBD=2336 YHG=2305>the " XBD=2322 XHG=2193 YBD=2336 YHG=2305>Oxford " XBD=2473 XHG=2347 YBD=2343 YHG=2305>degrees " XBD=2525 XHG=2494 YBD=2336 YHG=2305>of" XBD=1456 XHG=1373 YBD=2383 YHG=2359>B.sc. " XBD=1546 XHG=1478 YBD=2383 YHG=2352>and " XBD=1630 XHG=1564 YBD=2383 YHG=2360>B.A. " XBD=1734 XHG=1651 YBD=2383 YHG=2352>with " XBD=1901 XHG=1751 YBD=2383 YHG=2352>honours " XBD=1955 XHG=1920 YBD=2383 YHG=2352>in " XBD=2103 XHG=1974 YBD=2383 YHG=2352>natural " XBD=2251 XHG=2123 YBD=2384 YHG=2352>science " XBD=2335 XHG=2270 YBD=2383 YHG=2352>and " XBD=2426 XHG=2353 YBD=2383 YHG=2352>four " XBD=2521 XHG=2443 YBD=2390 YHG=2361>years" XBD=1455 XHG=1373 YBD=2430 YHG=2399>later " XBD=1658 XHG=1469 YBD=2437 YHG=2399>proceeded " XBD=1706 XHG=1671 YBD=2430 YHG=2406>to " XBD=1794 XHG=1719 YBD=2429 YHG=2407>M.A. " XBD=1885 XHG=1830 YBD=2429 YHG=2399>He " XBD=1963 XHG=1898 YBD=2430 YHG=2409>was " XBD=2019 XHG=1977 YBD=2429 YHG=2408>an " XBD=2199 XHG=2033 YBD=2429 YHG=2399>examiner " XBD=2245 XHG=2211 YBD=2429 YHG=2399>in " XBD=2370 XHG=2257 YBD=2437 YHG=2399>public " XBD=2486 XHG=2382 YBD=2429 YHG=2398>health " XBD=2522 XHG=2496 YBD=2428 YHG=2403>at" XBD=1507 XHG=1374 YBD=2476 YHG=2445>Oxford " XBD=1731 XHG=1526 YBD=2483 YHG=2445>University. " XBD=1801 XHG=1760 YBD=2475 YHG=2445>In " XBD=1875 XHG=1818 YBD=2476 YHG=2445>the " XBD=2041 XHG=1895 YBD=2476 YHG=2446>1939-45 " XBD=2126 XHG=2059 YBD=2475 YHG=2454>war " XBD=2184 XHG=2142 YBD=2476 YHG=2445>he " XBD=2316 XHG=2202 YBD=2476 YHG=2445>served " XBD=2366 XHG=2333 YBD=2476 YHG=2455>as " XBD=2396 XHG=2379 YBD=2475 YHG=2454>a " XBD=2521 XHG=2409 YBD=2476 YHG=2444>colonel" XBD=1408 XHG=1372 YBD=2522 YHG=2492>in " XBD=1490 XHG=1433 YBD=2523 YHG=2492>the " XBD=1629 XHG=1516 YBD=2523 YHG=2492>Home " XBD=1786 XHG=1657 YBD=2523 YHG=2491>Guard. " XBD=1921 XHG=1825 YBD=2523 YHG=2492>After " XBD=1997 XHG=1946 YBD=2522 YHG=2491>his " XBD=2214 XHG=2023 YBD=2523 YHG=2492>retirement " XBD=2273 XHG=2238 YBD=2522 YHG=2492>in " XBD=2380 XHG=2300 YBD=2522 YHG=2492>1953 " XBD=2444 XHG=2403 YBD=2522 YHG=2491>he " XBD=2520 XHG=2466 YBD=2522 YHG=2500>was

" XBD=1546 XHG=1372 YBD=2569 YHG=2538>chairman " XBD=1612 XHG=1573 YBD=2570 YHG=2539>of " XBD=1693 XHG=1636 YBD=2569 YHG=2539>the " XBD=1881 XHG=1721 YBD=2577 YHG=2538>Banbury " XBD=2051 XHG=1908 YBD=2577 YHG=2538>hospital " XBD=2309 XHG=2078 YBD=2576 YHG=2546>management " XBD=2519 XHG=2336 YBD=2569 YHG=2538>committee." XBD=1486 XHG=1372 YBD=2617 YHG=2585>Three " XBD=1602 XHG=1509 YBD=2624 YHG=2595>years " XBD=1687 XHG=1625 YBD=2623 YHG=2594>ago " XBD=1752 XHG=1709 YBD=2616 YHG=2585>he " XBD=1897 XHG=1774 YBD=2617 YHG=2586>moved " XBD=1953 XHG=1918 YBD=2616 YHG=2593>to " XBD=2193 XHG=1976 YBD=2616 YHG=2585>Eastbourne." XBD=1478 XHG=1415 YBD=2662 YHG=2632>Dr. " XBD=1661 XHG=1500 YBD=2670 YHG=2632>Jennings " XBD=1790 XHG=1682 YBD=2662 YHG=2631>leaves " XBD=1828 XHG=1810 YBD=2662 YHG=2641>a " XBD=1968 XHG=1848 YBD=2662 YHG=2632>widow " XBD=2053 XHG=1987 YBD=2663 YHG=2631>and " XBD=2138 XHG=2072 YBD=2662 YHG=2638>two " XBD=2344 XHG=2158 YBD=2669 YHG=2631>daughters." XBD=1468 XHG=1418 YBD=2729 YHG=2696>N. " XBD=1522 XHG=1491 YBD=2735 YHG=2695>J. " XBD=1586 XHG=1545 YBD=2729 YHG=2695>E. " XBD=1745 XHG=1608 YBD=2729 YHG=2695>writes:" XBD=1513 XHG=1415 YBD=2786 YHG=2755>&dquo; Dr. " XBD=1700 XHG=1539 YBD=2792 YHG=2755>Jennings " XBD=1791 XHG=1725 YBD=2784 YHG=2754>will " XBD=1856 XHG=1815 YBD=2785 YHG=2755>be " XBD=2110 XHG=1880 YBD=2785 YHG=2753>remembered " XBD=2184 XHG=2132 YBD=2784 YHG=2754>for " XBD=2257 XHG=2206 YBD=2784 YHG=2754>his " XBD=2520 XHG=2281 YBD=2792 YHG=2753>championship" XBD=1409 XHG=1369 YBD=2831 YHG=2801>of " XBD=1479 XHG=1421 YBD=2831 YHG=2801>the " XBD=1555 XHG=1494 YBD=2832 YHG=2811>use " XBD=1610 XHG=1571 YBD=2832 YHG=2801>of " XBD=1755 XHG=1622 YBD=2839 YHG=2800>general " XBD=2002 XHG=1771 YBD=2838 YHG=2801>practitioners " XBD=2053 XHG=2019 YBD=2830 YHG=2800>in " XBD=2126 XHG=2069 YBD=2831 YHG=2801>the " XBD=2382 XHG=2141 YBD=2838 YHG=2800>public-health " XBD=2519 XHG=2398 YBD=2831 YHG=2800>service." XBD=1424 XHG=1369 YBD=2878 YHG=2847>He " XBD=1541 XHG=1442 YBD=2879 YHG=2847>made " XBD=1619 XHG=1558 YBD=2878 YHG=2847>full " XBD=1697 XHG=1637 YBD=2878 YHG=2857>use " XBD=1754 XHG=1714 YBD=2878 YHG=2847>of " XBD=1853 XHG=1768 YBD=2878 YHG=2847>their " XBD=2011 XHG=1871 YBD=2878 YHG=2847>services " XBD=2063 XHG=2029 YBD=2877 YHG=2847>in " XBD=2271 XHG=2080 YBD=2885 YHG=2847>preference " XBD=2321 XHG=2288 YBD=2877 YHG=2853>to " XBD=2521 XHG=2338 YBD=2885 YHG=2846>appointing" XBD=1578 XHG=1369 YBD=2925 YHG=2894>whole-time " XBD=1686 XHG=1600 YBD=2925 YHG=2894>staff. " XBD=1799 XHG=1723 YBD=2924 YHG=2894>The " XBD=1923 XHG=1821 YBD=2924 YHG=2894>strain " XBD=1983 XHG=1944 YBD=2925 YHG=2894>of " XBD=2058 XHG=2001 YBD=2925 YHG=2894>the " XBD=2145 XHG=2078 YBD=2925 YHG=2903>war " XBD=2257 XHG=2166 YBD=2932 YHG=2903>years " XBD=2342 XHG=2279 YBD=2924 YHG=2903>was " XBD=2397 XHG=2363 YBD=2924 YHG=2900>to " XBD=2522 XHG=2417 YBD=2931 YHG=2893>justify" XBD=1421 XHG=1368 YBD=2971 YHG=2939>his " XBD=1532 XHG=1443 YBD=2978 YHG=2941>good " XBD=1730 XHG=1553 YBD=2978 YHG=2941>judgment " XBD=1786 XHG=1752 YBD=2970 YHG=2940>in " XBD=1879 XHG=1807 YBD=2970 YHG=2940>that " XBD=1942 XHG=1901 YBD=2971 YHG=2950>an " XBD=2127 XHG=1964 YBD=2978 YHG=2941>adequate " XBD=2387 XHG=2147 YBD=2978 YHG=2939>public-health " XBD=2521 XHG=2408 YBD=2970 YHG=2940>service" XBD=1435 XHG=1368 YBD=3017 YHG=2996>was " XBD=1535 XHG=1461 YBD=3017 YHG=2987>well " XBD=1777 XHG=1561 YBD=3017 YHG=2986>maintained. " XBD=1880 XHG=1817 YBD=3017 YHG=2986>His " XBD=2083 XHG=1906 YBD=3017 YHG=2986>insistence " XBD=2179 XHG=2107 YBD=3017 YHG=2986>that " XBD=2259 XHG=2203 YBD=3017 YHG=2986>the " XBD=2410 XHG=2284 YBD=3024 YHG=2986>general " XBD=2520 XHG=2433 YBD=3024 YHG=2996>prac-" XBD=1504 XHG=1367 YBD=3063 YHG=3032>titioner " XBD=1615 XHG=1524 YBD=3063 YHG=3039>must " XBD=1678 XHG=1636 YBD=3064 YHG=3034>be " XBD=1716 XHG=1698 YBD=3063 YHG=3043>a " XBD=1799 XHG=1736 YBD=3070 YHG=3033>key " XBD=1923 XHG=1817 YBD=3070 YHG=3032>figure " XBD=1978 XHG=1943 YBD=3063 YHG=3032>in " XBD=2054 XHG=1998 YBD=3063 YHG=3033>the " XBD=2316 XHG=2073 YBD=3071 YHG=3032>public-health " XBD=2453 XHG=2336 YBD=3063 YHG=3032>service " XBD=2520 XHG=2471 YBD=3063 YHG=3032>led" XBD=1403 XHG=1367 YBD=3109 YHG=3085>to " XBD=1447 XHG=1429 YBD=3109 YHG=3089>a " XBD=1577 XHG=1473 YBD=3109 YHG=3079>much " XBD=1705 XHG=1602 YBD=3111 YHG=3079>wider " XBD=1791 XHG=1731 YBD=3109 YHG=3089>use " XBD=1855 XHG=1816 YBD=3109 YHG=3078>of " XBD=1933 XHG=1876 YBD=3109 YHG=3079>the " XBD=2071 XHG=1959 YBD=3109 YHG=3078>health " XBD=2225 XHG=2096 YBD=3110 YHG=3079>visitors " XBD=2296 XHG=2252 YBD=3117 YHG=3079>by " XBD=2374 XHG=2319 YBD=3109 YHG=3079>the " XBD=2520 XHG=2398 YBD=3116 YHG=3078>general" XBD=1600 XHG=1367 YBD=3163 YHG=3124>practitioners " XBD=1655 XHG=1619 YBD=3155 YHG=3125>in " XBD=1730 XHG=1673 YBD=3155 YHG=3125>the " XBD=1910 XHG=1748 YBD=3163 YHG=3131>post-war " XBD=2032 XHG=1927 YBD=3163 YHG=3134>years, " XBD=2117 XHG=2051 YBD=3156 YHG=3125>and " XBD=2200 XHG=2135 YBD=3156 YHG=3125>this " XBD=2253 XHG=2218 YBD=3155 YHG=3125>in " XBD=2311 XHG=2270 YBD=3155 YHG=3126>its " XBD=2404 XHG=2329 YBD=3155 YHG=3132>turn " XBD=2471 XHG=2421 YBD=3156 YHG=3125>led " XBD=2520 XHG=2488 YBD=3156 YHG=3132>to" XBD=1425 XHG=1367 YBD=3201 YHG=3171>the " XBD=1704 XHG=1451 YBD=3202 YHG=3171>establishment " XBD=1769 XHG=1730 YBD=3201 YHG=3171>of " XBD=1808 XHG=1791 YBD=3200 YHG=3180>a " XBD=2079 XHG=1833 YBD=3201 YHG=3171>health-visitor " XBD=2216 XHG=2104 YBD=3202 YHG=3171>school " XBD=2276 XHG=2241 YBD=3202 YHG=3171>in " XBD=2518 XHG=2301 YBD=3202 YHG=3171>Oxfordshire.

" XBD=1422 XHG=1367 YBD=3247 YHG=3217>He " XBD=1511 XHG=1445 YBD=3247 YHG=3226>was " XBD=1553 XHG=1536 YBD=3247 YHG=3226>a " XBD=1651 XHG=1576 YBD=3255 YHG=3224>past " XBD=1845 XHG=1674 YBD=3247 YHG=3217>chairman " XBD=1908 XHG=1868 YBD=3247 YHG=3217>of " XBD=1983 XHG=1926 YBD=3247 YHG=3218>the " XBD=2142 XHG=2007 YBD=3255 YHG=3217>County " XBD=2310 XHG=2164 YBD=3248 YHG=3217>Medical " XBD=2464 XHG=2333 YBD=3248 YHG=3218>Officers " XBD=2522 XHG=2486 YBD=3248 YHG=3218>of" XBD=1493 XHG=1367 YBD=3293 YHG=3262>Health " XBD=1682 XHG=1514 YBD=3301 YHG=3262>Society.&dquo;

" XBD=1472 XHG=1415 YBD=3358 YHG=3325>M. " XBD=1526 XHG=1494 YBD=3364 YHG=3324>J. " XBD=1586 XHG=1547 YBD=3359 YHG=3325>P. " XBD=1672 XHG=1608 YBD=3360 YHG=3325>has " XBD=1774 XHG=1694 YBD=3358 YHG=3333>sent " XBD=1855 XHG=1794 YBD=3359 YHG=3325>the " XBD=2061 XHG=1876 YBD=3367 YHG=3325>following " XBD=2245 XHG=2080 YBD=3367 YHG=3326>personal " XBD=2366 XHG=2264 YBD=3360 YHG=3327>lines:" XBD=1565 XHG=1411 YBD=3422 YHG=3384>&dquo; Henry " XBD=1753 XHG=1592 YBD=3422 YHG=3385>Jennings " XBD=1848 XHG=1782 YBD=3415 YHG=3394>was " XBD=1933 XHG=1876 YBD=3415 YHG=3385>the " XBD=2033 XHG=1961 YBD=3415 YHG=3385>first " XBD=2228 XHG=2060 YBD=3415 YHG=3385>chairman " XBD=2293 XHG=2255 YBD=3416 YHG=3385>of " XBD=2369 XHG=2315 YBD=3416 YHG=3385>the " XBD=2516 XHG=2396 YBD=3417 YHG=3385>Oxford" XBD=1508 XHG=1365 YBD=3461 YHG=3430>medical " XBD=1662 XHG=1533 YBD=3461 YHG=3431>officers " XBD=1727 XHG=1687 YBD=3461 YHG=3430>of " XBD=1860 XHG=1746 YBD=3461 YHG=3430>health " XBD=1998 XHG=1881 YBD=3461 YHG=3431>liaison " XBD=2220 XHG=2019 YBD=3467 YHG=3432>committee, " XBD=2305 XHG=2241 YBD=3462 YHG=3432>and " XBD=2349 XHG=2325 YBD=3461 YHG=3432>it " XBD=2393 XHG=2368 YBD=3462 YHG=3431>is " XBD=2445 XHG=2413 YBD=3462 YHG=3438>to " XBD=2514 XHG=2467 YBD=3462 YHG=3432>his" XBD=1471 XHG=1365 YBD=3507 YHG=3476>credit " XBD=1575 XHG=1503 YBD=3507 YHG=3476>that " XBD=1691 XHG=1607 YBD=3507 YHG=3477>such " XBD=1741 XHG=1723 YBD=3506 YHG=3486>a " XBD=1887 XHG=1773 YBD=3514 YHG=3477>happy " XBD=2133 XHG=1918 YBD=3515 YHG=3476>relationship " XBD=2223 XHG=2165 YBD=3508 YHG=3477>has " XBD=2368 XHG=2254 YBD=3515 YHG=3477>always " XBD=2514 XHG=2399 YBD=3508 YHG=3477>existed" XBD=1518 XHG=1364 YBD=3553 YHG=3522>between " XBD=1604 XHG=1548 YBD=3552 YHG=3522>the " XBD=1883 XHG=1635 YBD=3560 YHG=3522>public-health " XBD=1979 XHG=1913 YBD=3552 YHG=3522>and " XBD=2274 XHG=2010 YBD=3560 YHG=3522>hospital-board " XBD=2379 XHG=2303 YBD=3553 YHG=3523>staff " XBD=2435 XHG=2403 YBD=3553 YHG=3523>in " XBD=2513 XHG=2462 YBD=3555 YHG=3523>the" XBD=1497 XHG=1364 YBD=3598 YHG=3568>Oxford " XBD=1652 XHG=1526 YBD=3605 YHG=3568>region. " XBD=1741 XHG=1694 YBD=3598 YHG=3568>As " XBD=1942 XHG=1771 YBD=3598 YHG=3568>chairman " XBD=2009 XHG=1970 YBD=3598 YHG=3568>of " XBD=2090 XHG=2034 YBD=3598 YHG=3568>the " XBD=2275 XHG=2119 YBD=3606 YHG=3569>Banbury " XBD=2448 XHG=2301 YBD=3605 YHG=3568>H.M.C., " XBD=2513 XHG=2473 YBD=3600 YHG=3569>he" XBD=1554 XHG=1363 YBD=3644 YHG=3614>undertook " XBD=1625 XHG=1573 YBD=3643 YHG=3613>his " XBD=1922 XHG=1647 YBD=3650 YHG=3613>responsibilities " XBD=2026 XHG=1944 YBD=3643 YHG=3613>with " XBD=2137 XHG=2046 YBD=3650 YHG=3621>great " XBD=2404 XHG=2157 YBD=3651 YHG=3614>thoroughness, " XBD=2512 XHG=2425 YBD=3645 YHG=3615>made

5. Reid, H. A. ibid. 1965, ii, 5.6. Mutt, V., Jorpes, J. E. Biochem. biophys. Res. Comm. 1967, 26, 392.

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3-3 stack defense. 3-3 defense vs PRO TWINS OVER TWINS TRIPS WIDE TIGHT ACE WING OPEN KINGS TREY TWINS OVER WING OVER TWINS