tularemia - pasteur
TRANSCRIPT
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Report of International training course on
Tularemia 15-17 December 2015
Akanlu, Kabudar Ahang, Hamadan, Iran
International training course on Tularemia was held in collaboration with scholars from
Sweden, France, Turkey, and Iran in the national reference laboratory for tularemia,
plague and Q fever, Research Centre for Emerging and Reemerging infectious diseases.
Infectious disease specialists, microbiologists, epidemiologists, rodentologist, and
medical entomologist from 9 countries (Sudan, Bulgaria, Pakistan, China, Turkey,
Malaysia, Sweden, France and Iran) and participants from 7 universities and local
institutions attended the course. Various aspects of the disease including biology and
epidemiology of the causing agent F. tularensis, vector-borne transmission, reservoirs,
symptoms, treatment, and diagnosis methods as well as international joints projects in
this field were discussed.
Introduction
Tularemia is a zoonotic disease transmitted by direct contact with infected animals, or
through arthropod bites, inhalation of contaminated aerosols, ingestion of contaminated
meat or water, or skin contact with any infected material. This disease has a wide
distribution covering much of the northern hemisphere including Iran and its northern,
northeastern, and northwestern neighboring countries. Despite outbreaks in various
countries in recent years, the disease remains underreported as physicians, infectious
disease specialists, microbiologist, and health care workers’ knowledge on natural cycle
of the agent and clinical manifestations of the disease is not enough and updated to help
them recognize the disease.
The participants of the course improved their knowledge and practice on surveillance,
diagnosis, and clinical management of tularemia and enhanced their abilities to
investigate future outbreaks in their countries.
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Team of Instructors
- Dr Anders Johansson, Clinical Bacteriologist,
Assistant Professor, Umeå University, Department
of Clinical Microbiology, Umeå, Sweden and
Department Head, Infection Control Västerbotten
County, Sweden.
- Dr Max Maurin, Clinical Bacteriologist,
Professor, Grenoble Alpes University, Grenoble,
France.
- Dr Aynur Karadenizli, Infectious Disease
specialist and Clinical Microbiologist, Professor,
Kocaeli University, Department of Medical
Microbiology, Kocaeli, Turkey.
- Dr Ehsan Mostafavi, Epidemiologist, Associate
Professor, Director of Research centre of
Emerging and Reemerging Infectious Diseases,
Pasteur Institute of Iran, Tehran, Iran.
- Dr Abdolrazagh Hashemi Shahraki,
Microbiologist, Assistant Professor, Department of
Epidemiology, Pasteur Institute of Iran, Tehran,
Iran
- Dr Saied Reza Naddaf, Entomologist, Associate
Professor, Department of Parasitology, Pasteur
Institute of Iran, Tehran, Iran.
- Dr Roohollah Siahsarvie, Rodentologist,
Rodentology Research group, Ferdowsi University
of Mashhad, Mashhad, Iran.
Organizers
Research Centre for Emerging and Reemerging infectious diseases, Pasteur
Institute of Iran, Tehran, Iran
Centre for Communicable Diseases Control and Prevention, Ministry of Health
and Medical Education, Tehran, Iran
Partners
Umeå University, Department of Clinical Microbiology, Umeå, Sweden
Grenoble Alpes University, Grenoble University Hospital, Department of Clinical
Microbiology, Grenoble, France
Kocaeli University, Department of Medical Microbiology, Kocaeli, Turkey.
Ferdowsi University of Mashhad, Rodentology Research group, Mashhad, Iran.
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Sponsors
Centre for Communicable Diseases Control and Prevention, Ministry of Health
and Medical Education, Tehran, Iran
Research Centre for Emerging and Reemerging infectious diseases, Pasteur
Institute of Iran, Tehran, Iran
World Health Organization
Embassy of France in Iran
Venue
The course was held in the Research
Centre for Emerging and
Reemerging infectious diseases,
which is the national reference
center for diagnosis and research on
Plague, Tularemia and Q fever in
Iran.
It is a branch of Pasteur Institute of
Iran located in Western Iran located
in Akanlu village in Kabudrahang
district.
Duration
The course took place in 3 working days (15-17 December 2015).
Participants and Sessions
There were 25 participants from China (1),
Sudan (1), Bulgaria (1), Pakistan (1), Turkey
(1), Malaysia (1), Sweden (1), France (1) and
Iran (17).
The tutors presented the topics in 13 lectures
and 6 practical sessions.
Course Manual, PPTs and pictures
The course materials included key educational papers and related guidelines were
provided during the course and files were shared with the participants in a flash-drive.
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Social Events
Visiting the Rural Homes of the Region
The Participants of the course visited one of the
houses in the Akanlu village and closely met the
lifestyle of the villagers and their agricultural
products.
Visiting the Snowy Mountains
Snowing made a perfect opportunity to make
real treasured memories outdoors.
The participants had this opportunity to walk and
play around the snowy mountains near the
course venue.
It was more interesting for those who had never
seen snow!
Alisadr Cave
At the end of the course the participants visited
the Alisadr Cave.
This cave is the world's largest water cave which
attracts millions of visitors every year. The cave
is located 75 kilometers northwest of Hamadan
and 70 km from Akanlu village.
Traditional Restaurant
Participants of the course took last day lunch in a
traditional restaurant eating Ābgoosht.
Ābgoosht (literally "meat juice") is a Persian and
Mesopotamian stew. It is also called Dizi, which
refers to the traditional stone crocks it is served
in. Ābgoosht is usually made with lamb,
chickpeas, white beans, onion, potatoes,
and tomatoes, turmeric, and dried lime.
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List of the Participants
Name Country Education Institute
Aynur Karadenzli Turkey Medical Microbiology Kocaeli University
Anders Johansson Sweden Physician Umea University
Mohamed Elamin Abdelmagid Sudan MD Community Medicine FMOH
Mohammad Ishaq Pakistan MD, MSPH Ministry of Health
Rukumani Devi Velayuthan Malaysia MBBS, MPATH University Malaya
Max Maurin France Medical Microbiology Université Grenoble
Yanhua Wang China Medical Microbiology China CDC
Hristo Najdenski Bulgaria Veterinarian Institute of Microbiology
Ehsan Mostafavi Iran Epidemiology Pasteur institute of Iran
Abdolrazagh Hashemi Shahraki
Iran Medical Microbiology Pasteur institute of Iran
Saber Esmaeili Iran Medical Microbiology Pasteur institute of Iran
Badri Mohseni Iran Veterinarian Iranian Veterinary Organization
Saied Reza Naddaf Iran Medical Entomology Pasteur institute of Iran
Ahmad Ghasemi Iran Medical Microbiology Pasteur institute of Iran
Shabnam Tehrani Iran MD- Infectious Disease Shahid Beheshti University of Medical Sciences
Arash Seifi Iran MD- Infectious Disease Tehran University of Medical Sciences
Mohammad Javad Nasiri Iran Medical Microbiology Shahid Beheshti University of Medical Sciences
Hossein Kazemian Iran Medical Microbiology Tehran University of Medical Sciences
Jalil Kardan Yamchi Iran Medical Microbiology Tehran University of Medical Sciences
Hossein Akbari Iran Epidemiology Iranian CDC
Hossein Ansari Iran Epidemiology Zahedan University of Medical Sciences
Zakaria Bameri Iran Medical Microbiology Pasteur institute of Iran
Mohammad Ali Malekan Iran Medical Microbiology Pasteur institute of Iran
Roohollah Siahsarvie Iran Rodentologist Ferdowsi University of Mashhad
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Group photos
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Schedule of the course
Presenter Program Hour Time
- Opening and welcome 8:00-8:15 M
orn
ing
Th
e fi
rst
da
y
(15
th D
ecem
ber
)
Film An Introduction to Pasteur institute of Iran 8:15-8:45
Dr Ehsan Mostafavi An Introduction to Research Centre of Emerging and
Reemerging infectious diseases
8:45-9:30
Dr Anders Johansson The distribution of Tularemia in the world 9:30 – 9:50
Dr Ehsan Mostafavi The situation of Tularemia in Iran 9:50-10:10
Dr Aynur Karadenizli The situation of Tularemia in Turkey 10:10-10:30
Refreshments 10:30 - 11:11
Dr Abdolrazagh Hashemi Bacteriology 11:00 – 12:00
Dr SaeedReza Naddaf Vectors and of Tularemia in the nature 12:00-13:00
Aft
ern
oo
n
Lunch 13:00 – 14:00
Dr Roohollah Siahsarvie Reservoirs of Tularemia in the nature 14:00 – 15:00
Dr Mostafavi,
Dr Naddaf
Practical section (Epidemiologists and Bacteriologists
Group1)
Field investigation (Hunting, Blood sampling and tissue
sampling from the rodents, wild animals, water, vectors)
15:00-18:00
Dr Hashemi,
Dr Maurin
Practical section (Bacteriologists Group 2)
Laboratory procedures (processing the samples, culturing,
DNA extraction, Real time PCR)
Dr Karadenizli, Dr Johansson, Scenario (Physicians)
Visiting the rural homes of the region 19:00-20:00
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Dr Max Maurin Source of infection, infectious routes, and clinical outcome
according to F. tularensis subspecies
8:00 – 9:00
Mo
rnin
g
Th
e se
con
d d
ay
(16
th D
ecem
ber
) Dr Anders Johansson Clinical expression in humans (Signs and symptoms,
Differential diagnoses, Case definitions) 9:00-10:00
Reception and Refreshments 10:00 – 10:30
Dr Max Maurin Laboratory diagnostics 10:30 – 12:15
Dr Max Maurin Biosafety considerations 12:15 – 13:00
Lunch 13:00 – 14:00
Dr Hashemi,
Dr Maurin,
Bacteriologists Group1: Laboratory procedures (processing
the samples, culturing, DNA extraction, Real time PCR)
15:00-18:00
Aft
ern
oo
n
Dr Mostafavi,
Dr Naddaf
Practical section (Bacteriologists Group2)
Field investigation (Hunting, Blood sampling and tissue
sampling from the rodents, wild animals, water, vectors) Dr Johansson, Dr Karadenizli Scenario (Physicians and Epidemiologists)
Dr Anders Johansson Treatment, prophylaxis and vaccination against Tularemia 8:30 – 9:30
Mo
rnin
g
Th
e T
hir
d d
ay
(17
th D
ecem
ber
)
Dr Aynur Karadenizli Investigation of the waterborne tularemia outbreaks 9:30 – 10:30
Refreshment 10:15 – 10:30
Conclusion and closing 10:30 – 12:00
Lunch in a traditional restaurant 13:00 – 14:00
Aft
ern
oo
n
Visiting Alisadr Cave 14:00-17:00
Coming back to Tehran 17:00-22:00