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Treatment of Arthritis

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Page 1: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different

Treatment of Arthritis

Page 2: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different

Arthritis is a form of joint disorder that involves inflammation of one or more joints.  

There are over 100 different forms of arthritis. 

The most common form,  osteoarthritis (degenerative joint disease), is a result of trauma to the joint, infection of the joint, or age. 

Other  arthritis  forms  are rheumatoid arthritis, psoriatic arthritis,  and  related autoimmune diseases. Septic arthritis is  caused by joint infection

Page 3: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 4: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 5: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 6: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different

Medicinal Treatment for Arthritis

Pain Relief.The most common medication used for acute pain relief are NSAIDs

Corticosteroid: mainly used for treatment of rheumatoid arthritis

NSAIDs have gastrointestinal side effects

We have already covered NSAIDs in the previous lecture

Page 7: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 8: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 9: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 10: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different

Auranofin: 3 mg once a day for 2 weeks. Increase to 6 mg each day. 3-4 months

Aurothioglucose: 10 mg followed by 25 mg for the second and third doses, then 50 mg weekly until 0.8 to 1 g has been administered

Page 11: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 12: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 13: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 14: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
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See notes below this slide for pathophysiology of Gout.

Page 17: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different

Remember: FOR PAIN RELIEF NSAIDs SHOULD BE PRESCRIBED (also see colchicine)

Acute Gouty Attack

Page 18: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
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Drugs for Hyperuricemia

Page 21: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 22: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
Page 23: Treatment of Arthritis.  Arthritis is a form of joint disorder that involves inflammation of one or more joints. inflammation  There are over 100 different
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