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TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra & Joost Hutsebaut September 2009, Ghent

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Page 1: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP:A long term outcome and process study of a residential treatment for treatment refractory

adolescents with personality disorders

Dineke Feenstra & Joost Hutsebaut

September 2009, Ghent

Page 2: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

PTC De Viersprong

PTC De Viersprong is a third line mental health setting. It offers specialized assessment and treatment programs (outpatient, day hospital and inpatient) for adolescents and adults with personality disorders

De Viersprong has its own research department, the VISPD: Viersprong Institute for Studies on Personality Disorders

Page 3: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

Research group

Joost Hutsebaut Dineke Feenstra Annelies Laurenssen Jan van Busschbach Roel Verheul Els Havermans

Page 4: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

Background:Outcome research in adolescents

Progress in child- and adolescent psychotherapy outcome research:– Psychotherapy is an effective treatment for children and

adolescents (mood-, anxiety-, eating-, and conduct disorders) (Kazdin & Weisz, 2004).

– Improvement in methodological qualities of research (more controlled studies, treatment protocols etc.) (Kazdin, 2002).

Page 5: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

Background:Outcome research in adolescents

Limitations in child- and adolescent psychotherapy outcome research:– Uncovered area: personality disorders (PD) in adolescents

– Lack of developmental sensitivity: treatment models as well as outcome instruments are little developmentally sensitive

• Review of 25 empirically supported psychotherapies in adolescents (Weisz & Hawley, 2002)

– 14 effective treatments

– 7 adult models, 6 child models, 1 adolescent model (MST)

Page 6: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

Background: Treatment of PD in adolescents

Adolescents are left out of multidisciplinary guidelines for the treatment of PD’s

No evidence based models for the treatment of adolescent PD

Few handbooks: Kernberg, 2000 (psychodynamic approach); Bleiberg, 2001 (relational approach rooted in attachment theory); Miller et al., 2007 (DBT); Freeman & Reinecke, 2007

Page 7: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

Background:Outcome studies adolescents with PD

Chanen et al., 2008: – RCT Cognitive Analytic Therapy (CAT) versus manualised

good clinical care

Rathus & Miller, 2002: – Quasi experimental investigation of an adaptation of

Dialectical Behavior Therapy (DBT)

Page 8: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study: Rationale

Rationale: – First: little is known about severe personality disorders in

adolescents

– Second: little is known about intensive inpatient treatment (for personality disturbed adolescents)

– Third: we know little about developmental sensitive outcomes of psychotherapy for adolescents

Page 9: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Objectives

Objective 1: treatment outcome

Objective 2: prediction of treatment outcome

Objective 3: relation between relational changes and relapse

Page 10: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Design

Naturalistic study Include 130 adolescents with personality pathology

who are admitted to the inpatient unit of the youth department of De Viersprong (duration of treatment is 1 year)

Measurements at start of treatment, 6, 12 and 24 months after the start of treatment

Page 11: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Instruments

Instrument

Intake/ Start

of treatment

6 months after start

of treatment

12 months after start of treatment

24 months after start of treatment

General questionnaire

Anxiety Disorders Interview Schedule for DSM-IV (Adis-C)

Structured Clinical Interview for DSM IV axis II Personality Diusorders (SCID-II)

Brief Symptom Inventory (BSI)

Severity Indices of Personality Problems (SIPP-118)

Autnomy and attachtment quest. (AHV)

Depressive experiences quest. For Adolescents (DEQ-A)

Competence quest. for adolesc. (CBSA)

Life events

Quality of relationships Inventory (QRI)

Family Assessment Device (FAD-N)

Outcome quest.

IQ (KAIT)

Stigma

Therapeutic alliance

Group cohesion

Page 12: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Sample charachteristics

Sample characteristics (baseline):– N = 133

– Gender = 113 female (85%); 20 male (15%)

– Mean age = 16.55 (range 14-19)

– Mean IQ = 104 (range 78-137)

Page 13: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Sample characteristics

Sample characteristics (baseline):– Axis I: 100 adolescents (75.19%) had at least 1 Axis I

disorder

* Other axis I disorders were diagnosed in less than 10% of the adolescents.

Axis I disorder N %

Dysthymic disorder 36 27.07

Social phobia 34 25.56

Major depressive disorder 16 12.03

PTSD 14 10.53

Any Axis I disorder 100 75.19

Page 14: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Sample characteristics

Sample characteristics (baseline):– Axis II: 63 adolescents (47.37%) had at least 1 Axis II

personality disorder

Axis II disorder N %

Borderline PD 33 24.81

Avoidant PD 22 16.54

Depressive PD 5 15.15

Obsessive-compulsive PD 4 3.01

PD not otherwise specified 7 5.26

Any PD 63 47.37

Page 15: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Drop out

Dropping out of the treatment:

N %

Drop out 44 33

No drop out 89 67

Total 133 100

Page 16: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Results symptom level (BSI)

Brief symptom inventory (BSI)

General symptomatology

00,20,40,60,8

11,21,41,61,8

2

Start of treatment 12 months after start oftreatment

BSI-score (PD)

BSI-score (no PD)

BSI-score (meanpatiënt)

BSI-score (meannormal)

Page 17: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Results personality functioning (SIPP)

SIPP domain self-control

3

4

5

6

7

Start of treatment 12 months after start of treatment

No PD

PD

SIPP domain social concordance

3

4

5

6

7

Start of treatment 12 months after start of treatment

No PD

PD

SIPP domain identity integration

3

4

5

6

7

Start of treatment 12 months after start of treatment

No PD

PD

SIPP domain relational capacities

3

4

5

6

7

Start of treatment 12 months after start of treatment

No PD

PD

SIPP domain responsibility

3

4

5

6

7

Start of treatment 12 months after start of treatment

No PD

PD

Page 18: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Results other outcome measures (self report)

Drug use

0

10

20

30

40

50

60

70

80

No drugs Monthly Weekly Daily

%

Start of treatment

12 months after start oftreatment

School

0

10

20

30

40

50

Not goingto school

Less thanhalf of the

time

Missingschool only

now andthen

Always

%

Start of treatment

12 months after start oftreatment

Self-harm

0

10

20

30

40

50

60

No self-harm

Monthly Weekly Daily

%

Start of treatment

12 months after start oftreatment

Contacts with police

0

20

40

60

80

100

No contact 1 >1

%

Start of treatment

12 months after start oftreatment

Page 19: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study:Strengths & limitations

Strengths:– Use of developmentally sensitive (and positive) outcome

instruments– Several measuring points– Including severely personality disturbed adolescents– Use of semi structured interviews to assess both Axis I and Axis

II disorders

Limitations: – No control group– High level of drop-out– Underrepresentation of boys– No treatment manual

Page 20: TRAP: A long term outcome and process study of a residential treatment for treatment refractory adolescents with personality disorders Dineke Feenstra

TRAP-study

Conclusion:– A group of severely disturbed adolescents underwent an

intensive inpatient treatment program. A large group of these adolescents dropped out of treatment. The adolescents that stayed in treatment showed improvement in symptom level, personality functioning and developmental tasks (f.e. school).

– This is a first step (pilot study) in investigating the uncovered area of adolescents with severe personality disorders. Further research is needed, investigating manualized treatment programs with methodologically stronger research designs.