traditional knowledge documentation: the traditional ......nov 13, 2009 · – monsonto soyabean...
TRANSCRIPT
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Traditional knowledge documentation: the
FICCI International Conference on Traditional KnowledgeFICCI, Federation House, Tansen Marg, New Delhi, 13th November 2009
Supported by: DIPP and WIPO
documentation: the Traditional Knowledge
Digital Library
V K Gupta, Senior Advisor and Director, TKDL, Council of Scientific and Industrial Research, Rafi Marg, New Delh;
E-mail: [email protected]
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Objective
•• Prevent Misappropriation of Prevent Misappropriation of Indian Traditional KnowledgeIndian Traditional Knowledge
–– Break Format & Language barriersBreak Format & Language barriers
•• For International Patent Offices For International Patent Offices •• For International Patent Offices For International Patent Offices onlyonly
•• Multilingual (French, German, Multilingual (French, German, Japanese, English & Spanish)Japanese, English & Spanish)
•• Creating new Intellectual Creating new Intellectual Property for promoting Access to Property for promoting Access to Medicines (Since 2008) Medicines (Since 2008)
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IndiaIndia–– TurmericTurmeric–– NeemNeem–– NeemNeem–– BasmatiBasmati
TKDL TKDL –– TKRC TKRC -- IPCIPC
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Studies on plants nn March 2000 March 2000 : 4896: 4896nn March 2003 March 2003 : 15000: 15000nn December 2005 December 2005 : 35587: 35587nn December 2008 December 2008 : 85000: 85000nn Medicinal Plant Patents / Year : 5000Medicinal Plant Patents / Year : 5000nn Medicinal Plant Patents / Year : 5000Medicinal Plant Patents / Year : 5000nn Possible Patents concerning Possible Patents concerning
Indian Plants / Year : 4000Indian Plants / Year : 4000nn Possible Patents on Indian Possible Patents on Indian
system of Medicinesystem of Medicineon yearly basis : 2000on yearly basis : 2000
nn Annual average Growth Rate Annual average Growth Rate between 2000between 2000--2008 : 200%2008 : 200%
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IPC & Medicinal Plants
61
Class
K
Sub
Class
35 78 ASection
Human Necessities
Medical or VeterinaryClass
Group
Sub Groups
Materials from Plants
Medical or VeterinaryScience; Hygiene
Preparation for Medical, Dental or Toilet Purposes
Extracts of Animal, Plant or Micro-organisms
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TKRC Classification Symbol
A
SECTION
01
CLASS
B 1/00 Main group
Or
CLASS
SUBCLASS
1/21 Sub group
GROUP
Section A – Ayurveda; Class 01 – Pharmaceutical PreparationsSub-Class B – Based on Animals; Group 1/00 – Based on Animals & their Products; Sub-group 1/21 - Milk
SUB-GROUP
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IGC & TKDLn Enhancement in IPC subgroups on medicinal plant from 1 to
200 & linking TKRC (25000 subgroups) to IPC, Recognition of TK by IPC & contribution to Quality Patent Search.
n Inclusion of 2 of CSIR Scientific Journals i.e. Indian Journal of Traditional Knowledge & Medicinal and Aromatic plants AbstractsAbstracts
n Contribution in establishing standard WIPO/GRTKF/IC/4/14 on setting up of databases & registries on Traditional Knowledge & Biological Genetic Resources
n Awareness Building on TKDL § Presentation in plenary of IGC-2002 & 2004§ Presentation in committee of Experts IPC-2001,2003
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Key Attributes of TKDL
BP/70 English
Title of Traditional Knowledge Knowledge Known Since
Guducyadi Kvatha(14)
100 years
TKRC CODE : A01A-1/1512, A01A-1/1592, A01A-1/1789, A01A-1/1815, A01A-1/1824, A01A-1/1966,
A01A-1/1988, A01A-1/2039, A01A-1/670, A01A-1/920, A01A-3/19, A01D-19/01
IPCCode : A61K35/78,A61K9/08,A61P31/12
English
DETAILS OF PROCESS / FORMULATION :
1.Guducyadi Kvatha(14) is a therapeutic single/compound formulation consisting of useful parts of following ingredient(s)Tinospora cordifolia (Guduci), Glycyrrhiza glabra (Yastimadhu, Klitaka (Substitute)), Pluchea lanceolata (Rasna), Desmodium gangeticum (Salaparni), Uraria picta (Prasniparni), Solanum xanthocarpum (Kantakari, Laksamana (Substitute drugs) (Sveta)), Solanum indicum (Brahti), Tribulus terrestris (Goksura), Pterocarpus santalinus (Rakta candana), Gmelina arborea (Gambhari), Sida cordifolia (Bala), Solanum xanthocarpum (Kantakari, Laksamana (Substitute drugs) (Sveta)) 2. Therapeutic composition/formulation is mentioned below :
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1 2 3 4 5 6
Tinospora cordifolia (Guduci) Glycyrrhiza glabra (Yastimadhu, Klitaka (Substit ute)) Pluchea lanceolata (Rasna) Desmodium gangeticum (Salaparni) Uraria picta (Prasniparni) Solanum xanthocarpum (Kantakari, Laksamana (Sub stitute drugs) (Sveta))
(Stem) (Root) (Leaf) (Root) (Root) (Root)
1 1 1 0.2 0.2 0.2
Part Part Part Part Part Part
English
7 8 9 10 11 12
stitute drugs) (Sveta)) Solanum indicum (Brahti) Tribulus terrestris (Goksura) Pterocarpus santalinus (Rakta candana) Gmelina arborea (Gambhari) Sida cordifolia (Bala) Solanum xanthocarpum (Kantakari, Laksamana (Sub stitute drugs) (Sveta))
(Root) (Root) (Heart Wood) (Fruit) (Root) (Whole Plant)
0.2 0.2 1 1 1 1
Part Part Part Part Part Part
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3. A composition as described above is formulated as (Decoction / Water Extract)(Kvatha) 4. Therapeutic composition mentioned above is prepared by Kvatha Curna/Kvatha: Drugs are cleaned and dried.
English
pp 13
5. It is useful in the treatment of Small pox(Masurika)
LIST OF DOCUMENTS WITH DATE OF PUBLICATION(PRIOR ART):
Nagin Das Chagan lal Saha
Bharat Bhaisjya Ratnakar, Gopi nath Bhisakratnen Vol II B. Jain publishers (New Delhi) Ed. Reprint - August 1999.
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JapaneseJapanese
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DisciplineDiscipline Current StatusCurrent Status
Ayurvedic formulationsAyurvedic formulations 81,50081,500
Unani formulationsUnani formulations 1,09,5001,09,500
TKDL ready to safeguard 2,03,200 medicinal formulations like Neem and Turmeric in Ayurveda ,Unani and Siddha which are present in 30 million A4 size pages, at International Level
Unani formulationsUnani formulations 1,09,5001,09,500
Siddha formulationsSiddha formulations 12,20012,200
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Cost/ Effectiveness of TKDLCost/ Effectiveness of TKDL
n TKDL Route– No. of A4 Size page information in 5 international
languages– Expenditure Incurred
n Translation Route
30 Million
1.4 Million US $
n Translation Route– Skill needed, knowledge of Ayurveda/ Unani/ Siddha/ Sanskrit/ Persian/
Tamil/ German/English/French/Japanese/Spanish/ Modern medicine & Science
– Incase above skill set was available, it would have costed 1.2 billion US $,a team of 5000 and time period of 60 years against the team of 100 and cost of 2.0 million US$
– TKDL protects 0.2 million formulations based on Neem cases, cost of such protection would be astronomical(200 billion US$).
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TKDL has made unparalled Contributions to the international policy context of the patent system and it context of the patent system and it offers a valuable template for others
Dr. Francis GurryDirector General
World Intellectual PropertyOrganization, Geneva
Date 05-Jan-2009
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TKDL & WORLD HEALTH ORGANIZATION
Regional consultation on Development of Traditional Medicines in the South East Asia Region, Pyongyoung, DPR Korea, 22-24 June 2005
Recommendation No.5
WHO should develop a model framework on replicating Traditional Knowledge Digital Library (India) suitable for adapting to individual
Country needs
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The information, along with a photographic scan of the relative verse, is then uploaded to an online database and translated into English, French, German, Spanish, Japanese and Hindi. So far, some 140,000 treatments have been entered into the have been entered into the Traditional Knowledge Digital Library (TKDL), a $2 million project launched five years ago to provide a direct link to what is regarded in the patent world as prior knowledge. The first of its kind, the TKDL is serving as a
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(CCEA has approved access to TKDL for (CCEA has approved access to TKDL for International Patent Offices)International Patent Offices)
•• UsersUsers–– Shall not disclose the content to third partyShall not disclose the content to third party–– Shall utilize for patent search & examiners, can give printouts to Shall utilize for patent search & examiners, can give printouts to
patent applicants for citation purposespatent applicants for citation purposes–– No use other than search & examinationNo use other than search & examination
Obligations of Providers & Users of TKDLIndia’s Strategy Non Disclosure Agreement with International Patent Offices
–– No use other than search & examinationNo use other than search & examination–– Will provide nonWill provide non--confidential information received from applicant confidential information received from applicant
on usage to provider on usage to provider –– Will give feedback for enhancing the features of TKDL Will give feedback for enhancing the features of TKDL
•• ProviderProvider–– Shall provide uninterrupted accessShall provide uninterrupted access–– Training to users (as and when needed)Training to users (as and when needed)–– Render assistance in search & examination (as & when needed)Render assistance in search & examination (as & when needed)–– Free to utilize for itself & can grant access to othersFree to utilize for itself & can grant access to others
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nn An improved patent granting process at an early An improved patent granting process at an early stage of patent examinations.stage of patent examinations.
nn A unique encyclopedia A unique encyclopedia
Views of EPO After Access (Feb 2009) to TKDL
nn Shedding light on grey areasShedding light on grey areas–– TKDL is precise and TKRC ensures meticulous TKDL is precise and TKRC ensures meticulous documentations documentations
–– Thanks to TKDL, patent examiners can prove Thanks to TKDL, patent examiners can prove exactly when and where a medical treatment exactly when and where a medical treatment became public knowledgebecame public knowledge
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TKDL Access Agreement with other International Patent Offices
n United States Patents & Trade Mark office (likely to be signed in Nov. 2009)– USPTO considers TKDL established by India is part of the very important work being done internationally w.r.t Traditional Knowledge databases. These databases will help to compliment the extensive prior art searches done by the patent examiners in the United States & around the world.United States & around the world.
n 11, other International search Authorities (Australia, Japan, Russia, Korea, China, Canada, Finland, Sweden, Austria, Spain, Nordic) – June 2010
n Balance Major International Patent offices– Possible by Dec. 2010
n Would protect globally Indian Traditional Medicinal open domain documented knowledge.
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Tangible Results of TKDL Access Agreement with EPO
• Normal route of opposition of an international patent - (10-15 years)– Neem (10 years)– Enola Beans (10 years)– Monsonto soyabean (13 years)
• TKDL route (Less than 12 Weeks)– Anti-Vitiligo Cream (3 week)– Anti Cancer Pistacia Vera (1 weeks)– Withdrawal of application by Uniliver on Cardio Vascular
tonic (3 Weeks) – Composition for Heart Disease and Health Products (9 Weeks)– Method for altering the Metabolism Characteristic of Food
Products (11 Weeks)– Method of Treatment or Management of Stress
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Impact of TKDL Access Agreement with European Patent office
• Identification of Patent Applications based on India’s Ayurveda, Unani & Siddha Systems of Medicine
• Citation from TKDL references through • Citation from TKDL references through Third Party Observations
• Method of Treatment or Management of Stress
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qAll systems of Indian system of Medicine have survived & grown in
TKDL for Validation of Ayurveda, Unani, & Siddha against each other
Medicine have survived & grown in Indian Subcontinent.
qUsed common Bio and Genetic Resources.
qFor Diseases of Subcontinent and its population.
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Digital Integration of Ayurveda, Unani & Siddha
Plant namePlant nameqq Ayurveda/Unani to Italic/Botanical Ayurveda/Unani to Italic/Botanical NameNameNameName
Disease NomenclatureDisease NomenclatureSearch on Classification symbols, Disease Search on Classification symbols, Disease Symptoms, Plant, Disease, etc.Symptoms, Plant, Disease, etc.
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Value Addition – Modern Science to TKDL
q Taxonomic Information, citation, synonyms, vernacular names, habitat, geographical information
q Morphological Informationq Cytological Informationq Cytological Informationq Germplasm Informationq Phytochemistryq Pharmalogical Informationq Pharmacognostical Informationq Toxicologyq Utilization
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MalariaMalariaSystem of System of MedicineMedicine
AYURVEDAAYURVEDA UNANIUNANI SIDDHASIDDHA COMMON MEDICINAL COMMON MEDICINAL PLANTSPLANTS
NO. of NO. of Formulations Formulations
15871587 4848 9595 Brahmi , Brahmi , Neerpirami, Neerpirami, Sapthalai, Sapthalai,
Diseases and Common Indian Medicinal Plants
Formulations Formulations in TKDLin TKDL
Sapthalai, Sapthalai, IndravaruniIndravaruni,,PippaliPippali , , Srmgika visa/ Srmgika visa/ VatsanabhaVatsanabha,Sarumam, Acacia ,Sarumam, Acacia arabica,Sambiran arabica,Sambiran ipoonduipoondu
Formulations Formulations in TKDL in TKDL
AindrirasayanamAindrirasayanam HabbHabb--ee--bukharbukhar
Sanda Sanda Marutha Marutha KuzhamabuKuzhamabu
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LDCsLDCs
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Stages of Formal Acceptance of Traditional Knowledge Classifications
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Stages of Formal Acceptance of Traditional Knowledge Classifications
Oct 2004 Deliberations on IPC-TKRC Concordance list of the new main group A61K 36/00
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Country-wise Periodicals included in PCT Minimum
S.No.
Country No. of NPL
S.No.
Country No. of NPL
1. USA 85 7. India 2
2. UK 20 8. France 2
3. Germany 15 9. Switzerland 23. Germany 15 9. Switzerland 2
4. Russia 6 10 Denmark 1
5. Japan 5 11 Czech 1
6. Netherlands 3 12 Italy 1
13 Croatia 1
TOTAL 144
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Section A – Ayurveda
Classl 01 – Pharmaceutical Preparations (Kalpana)l 02 – Personal Hygiene Preparationsl 03 – Dietary (food/food stuff or Beverages)l 04 – Biocides, Fumigatives (Dhupana, krmighna)
Section A Class 01 – Pharmaceutical Preparations (Kalpana)Sub-Classl 01A Based on Audbhida (Plants)l 01B Based on Jangama (Animals)l 01C Based on Parthiva (Minerals)l 01D Characterised by Roga (Diseases)l 01E Characterised by Karma (Action)l 01F Mode of Administrationl 01G MiscellaneousSub-Class: A01A – Pharmaceutical Preparations (Kalpana) Based onAudbhida (Plants)
l Group A01A 1/00 Whole medicinal plant2/00 Parts of medicinal plant used3/00 Characterised by Physical form
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Final Report GenerationFinal Report Generation
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Bacopa monnieri
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Citrullus colocynthis
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Alternanthera Sessilis
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Acorus calamus
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Piper longum
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Final Report GenerationFinal Report Generation
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Bacopa monnieri
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Citrullus colocynthis
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Alternanthera Sessilis
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Acorus calamus
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Piper longum
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Citation from TKDL references through Third Party Observations
1. Asthma/allergy therapy using nigella sativa; 2. Method of treatment or management of stress; 3. Hydroxylated Polymethoxyflavone Compositions; 4. Agents for sequestering serum aging factors and uses therefore;
United States of America – Total No. of Application 10
Citation from TKDL references through Third Party Observations
5. Cosmetic herbal compositions;6. Composition and method for facilitating the healing of non-healing
and slow-healing wounds and ulcerations;7. Compositions for diabetes treatment and prophylaxis
8. Bioactive compositions from theacea plants and processes for their production and use;
9. Compositions of bakuchiol and methods of making the same
10. Methods Of Treating Epiphora
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1. Anti-Inflammatory Agent; 2. Skin aging-preventing or improving agent; 3. Sleep-Improving Composition; 4. Composition for treating hepatitis c; 5. Senescence Inhibitor
Japan - Total No. of Application 5
Citation from TKDL references through Third Party Observations
5. Senescence Inhibitor
Great Britain - Total No. of Application 3
1. Treatment of inflammatory bowel disease
2. Polyphenol Extraction Process
3. Method and system for producing medicinal alcohol as a prophylatic or remedy for cancer, HIV, AIDS and autoimmune diseases
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Italy - Total No. of Application 3
1. A process for the preparation of ferutinine from ferula genus plants
2. Cancer treatment using natural plant products or essential oils or components from some pistacia species
3. Methods and composition for treating sore throat
Citation from TKDL references through Third Party Observations
3. Methods and composition for treating sore throat
Germany - Total No. of Application 2
1. Use of preparations, purifications and extracts of aloe 2. Skin treatment composition
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Citation from TKDL references through Third Party Observations
India - Total No. of Application 2
1. Biotherapeutics for mitigation of health disorders from terminalia arjuna
2. Process for producing enriched fractions of tetrahydroxycurcumin and tetrahydrotetrahydroxy-curcumin from the extracts of curcuma longa
Netherlands - Total No. of Application 1 Netherlands - Total No. of Application 1
1. Functional berry composition
New Zealand - Total No. of Application 1
1. A Composition for the treatment of Skin Diseases.
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1. Cysteine protease from ginger (zingiber) as a food improver and anti-inflammatory
Australia Total No. of Application 1
Citation from TKDL references through Third Party Observations
China Total No. of Application 1
1. Medicaments and food for treatment or prevention of obesity and/or diabetes containing cicer arietinum extract
Cyprus Total No. of Application 1
1. Treatment and prevention of inflammation
Kenya Total No. of Application 1
1. Herbal compositions for treatment of diabetes
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1. Natural product in cream with anti-vitiligo therapeutic properties
Spain Total No. of Application 1
Citation from TKDL references through Third Party Observations
South Korea Total No. of Application 1
1. Nelumbinis semen extract for preventing and treating ischemic heart disease and 1. Nelumbinis semen extract for preventing and treating ischemic heart disease and pharmaceutical composition and health food containing the same
Bulgaria Total No. of Application 1
1. Therapeutical composition for the treatment of dermatosis comprising an extract of calendula officinalis and hypericum perforatum
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Citation from TKDL references through Third Party Observations
Denmark Total No. of Application 1
1. Method for altering the metabolism characteristic of food products
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EPO PATENT NO: EP436257- (Neem)
Normal oppositions i.e. without TKDL and TKDL Access Agreement
Title Method for controlling fungi on plants by the aid of hydrophobic extracted neem oil
Applicant & Country Thermo Trilogy Corporation, 9145 Guilford Road Columbia, Maryland 21046-1883, USARoad Columbia, Maryland 21046-1883, USA
Date of Filing 20 December 1990
Date of Grant 04 August 1994
Date of Opposition 14 September 1994
Opposed by National and International NGOs
Final Rejection 8 March 2005
Period between Grant & Rejection
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US PATENT NO: 5894079- (Enola Beans)
US PATENT NO: 5894079- (Enola Beans)
Title Field bean cultivar named enola
Applicant & Country LARRY M. PROCTOR, DELTA, CO. USA
Date of Filing 15 November 1996
Date of Grant 13 April 1999Date of Grant 13 April 1999
Date of Opposition 20 December 2000
Opposed by International Center for Tropical Agriculture
Rejection at USPTO 2008
Rejection at US Federal Court 10 July 2009
Period between Grant & Rejection
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EPO PATENT NO: EP301749 –(Monsonto soybean)
EPO PATENT NO: EP301749 – (Monsonto soybean)
Title Particle-medicated transformation of soybean plants and lines
Applicant & Country Monsanto Company, 800 North Lindbergh Boulevard, St. Louis, Missouri 63167, USABoulevard, St. Louis, Missouri 63167, USA
Date of Filing 20 July 1988
Date of Grant 02 March 1994
Date of Opposition 6 October 1994
Opposed by Rural Advancement Foundation International (Canada)
Final Rejection 6 July 2007
Period between Grant & Rejection
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(Anti Cancer - Pistacia Vera )
EPO PATENT APPLICATION NO: EP1520585(Anti Cancer - Pistacia Vera )
Title Cancer treatment using natural plant products or essential oils or components from some pistacia species
Applicant & Country DATA MEDICA PADOVA S P A, ItalyApplicant & Country DATA MEDICA PADOVA S P A, ItalyDate of Filing 24 September 2004Date of intention to grant 19 February 2009Date of Third Party observation 08 July 2009Notice setting aside Intention to grant 14 July 2009Period between Third Party observation and setting aside Intention to grant
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(Anti-Vitiligo Cream )
EPO PATENT APPLICATION NO: EP1747786(Anti-Vitiligo Cream )
Title Natural Product Cream with Anti-Vitiligo Therapeutic Properties
Applicant & Country PERDIX EUROGROUP S L, Spain
Date of Filing 24 July 2006
Date of Intention to grant March 2009
Date of Third Party observation 01 July 2009
Notice setting aside Intention to grant
27 July 2009
Period between Third Party observation and setting aside Intention to grant
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(Cardio Vascular Tonic)
EPO PATENT APPLICATION NO: EP1607006(Cardio Vascular Tonic)
Title Cardio Vascular Tonic
Applicant & Country UNILEVER NV, Netherlands
Date of Filing 18 June 2004Date of Filing 18 June 2004
Date of Third Party observation 09 July 2009
Application deemed to be withdrawn
04 August 2009
Period between Third Party observation and withdrawal of application by applicant
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Composition for Heart Disease and Health Products
EPO PATENT APPLICATION NO: EP1781309(Composition for Heart Disease and Health Products)
Title Nelumbinis semen extract for preventing and treating ischemic heart disease and pharmaceutical composition and health food containing the same food containing the same
Applicant & Country Purimed Co., Ltd. Seoul, Korea
Date of Filing 09-June-2005
Date of Third Party observation 09-July-2009
Application deemed to be withdrawn
18-Sept-2009
Period between Third Party observation and setting aside Intention to grant
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EP 2044850
EPO PATENT APPLICATION NO: EP2044850(Method for altering the Metabolism Characteristic of Food Products )
Title Method for altering the Metabolism Characteristic of Food Products
Applicant & Country CLARA S APS, DENMARK
Date of Filing 19-Sept-2007
Date of Third Party observation 12-August-2009
Applicant withdraw his application
30-Oct-2009
Period between Third Party observation and setting aside Intention to grant
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Ep 1906980
EPO PATENT APPLICATION NO: EP1906980(Method of Treatment or Management of Stress)
Title Method of Treatment or Management of Stress
Applicant & Country NATREON INC, USA
Date of Filing 27-July-2006
Date of Third Party observation 05-June-2009
EPO Examination Report
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Eg 786
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Setting aside Intention to grant
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Eg 786-2
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Eg 585
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Setting aside Intention to grant
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Eg-585-2
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Ep 1607006
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Ep 006-2Deemed Withdrawn by Applicant
The European patent application is deemed to be withdrawn under article 94(4) EPC ,because the invitation to file observations on the communication from the examiningdivision was not compiled with.
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Ep 309
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Ep 309-2Deemed Withdrawn by Applicant
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Esc EP2044850
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Deemed Withdrawn by Applicant
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Ep-1906980
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Eg 1906980
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