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Topic 7 Nucleic Acids and Proteins

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Page 1: Topic 7 Nucleic Acids and Proteins. DNA Structure

Topic 7

Nucleic Acids and Proteins

Page 2: Topic 7 Nucleic Acids and Proteins. DNA Structure

DNA Structure

Page 3: Topic 7 Nucleic Acids and Proteins. DNA Structure

DNA Structure cont’d

Page 4: Topic 7 Nucleic Acids and Proteins. DNA Structure

DNA Replication

Page 5: Topic 7 Nucleic Acids and Proteins. DNA Structure

Organization of DNA in Eukaryotes

• Replication Initiation Sites

• Where the replication of DNA begins (may also be known as O.O.R.)

Page 6: Topic 7 Nucleic Acids and Proteins. DNA Structure

Nucleosomes• Globular structures that

contain 8 histone proteins, with DNA wrapped around 2 times

• Are connected to other nucleosomes by another histone protein (H1), known as a linker

• Essential for packaging DNA for mitosis/meiosis

• Involved in gene regulation

Page 7: Topic 7 Nucleic Acids and Proteins. DNA Structure

DNA Folding

Page 8: Topic 7 Nucleic Acids and Proteins. DNA Structure

DNA Folding

Page 9: Topic 7 Nucleic Acids and Proteins. DNA Structure

Repetitive Sequences

• Repetitive base sequences that are not translated

• Sometimes called satellite DNA• Sequences between 5-300 bp• May be repeated as much as 10,000x• Constitute 10-40% of euk. genomes• Function unknown• A vey small portion of euk. DNA is single

copy/unique genes

Page 10: Topic 7 Nucleic Acids and Proteins. DNA Structure

Introns and Exons


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