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(실습)

상용 프로그램을 이용한 생물학 네트워크 분석(IPA) – 실습(Recipe내용)

관심있는 Gene Set에서 시작하는 일반적인 네트워크 분석(MONGKIE 이용)

Seeding : Gene set(DEGs, Mutation Gene list, Fusion Gene list)

Expanding Network Visualization

Network Clustering

Sub-network annotation

Q & A

Contents

상용 프로그램을 이용한 생물학 네트워크 분석(IPA)

Does my drug target affect genes and proteins associated with a specific disease? Explore connections between a target and a disease.

IL1B

Macular degeneration

My Drug Target

A Specific Disease

Genes

Build Path Explorer

Help Legend

How to find associations between two diseases or cellular functions?

Muscle pain

Disease A

Genes

depression

Genes

Disease B

File New Compare…

Build Connect Overlay

What are the alternative indications for the drug/clinical candidate to my target gene XYZ?

Known Drug Targets Alternative Indication

Build Connect

Overlay Function & Disease

Overlay Drug

Build Grow

Path Designer